MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Bismuth subcitrate potassium | Bismuth subcitrate potassium is a compound bismuth salt with oral activity. Bismuth subcitrate potassium has antibacterial activity and can inhibit the growth of Campylobacter pyloridis with a MIC 50 of 8 μg/mL. Bismuth subcitrate potassium can be used in the study of gastrointestinal diseases infected by Campylobacter pyloridis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 880149-29-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-16102. |  |
| Bisoctrizole | Bisoctrizole is a broad-spectrum UV absorber that absorbs UVB and UVA rays while reflecting and scattering UV rays. Uses: Scientific research. Group: Signaling pathways. CAS No. 103597-45-1. Pack Sizes: 100 mg; 500 mg. Product ID: HY-B0897. | |
| Bisoprolol | Bisoprolol is a potent, selective and orally active β1-adrenergic receptor blocker with little activity on β2-receptor. Bisoprolol has the potential for hypertension, coronary artery disease and stable ventricular dysfunction research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 66722-44-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129029. | |
| Bisoprolol hemifumarate | Bisoprolol hemifumarate is a potent, selective and orally active ?1-adrenergic receptor blocker with little activity on ?2-receptor. Bisoprolol hemifumarate has the potential for hypertension, coronary artery disease and stable ventricular dysfunction research[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 104344-23-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-B0076. | |
| Bis-PEG3-acid | Bis-PEG3-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 96517-92-9. Pack Sizes: 100 mg; 250 mg. Product ID: HY-126891. | |
| Bisphenol A | Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cancers, cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders [1] [2] [3] [4] [5] [6] [7] [8] [9]. Uses: Scientific research. Group: Natural products. CAS No. 80-05-7. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-18260. | |
| Bisphenol A-d16 | Bisphenol A-d 16 is the deuterium labeled Bisphenol A[1]. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders[2][3]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 96210-87-6. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18260S. | |
| Bisphenol A-d6 | Bisphenol A-d 6 is the deuterium labeled Bisphenol A. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders[1][2][3]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 86588-58-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-18260S1. | |
| Bisphenol A (Standard) | Bisphenol A (Standard) is the analytical standard of Bisphenol A. This product is intended for research and analytical applications. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 80-05-7. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18260R. | |
| Bisphenol B | Bisphenol B is a very close structural analog of Bisphenol A (HY-18260), an endocrine disrupting chemical (EDC) and a substance of very high concern (SVHC) in the European Union (EU) for both human health. Bisphenol B shows endocrine disruptive properties or other adverse effects on animal models [1]. Uses: Scientific research. Group: Natural products. CAS No. 77-40-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 1 g. Product ID: HY-W013935. | |
| Bis(pinacolato)diborane | Bis(pinacolato)diborane is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 73183-34-3. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-79444. | |
| Bispyribac sodium | Bispyribac sodium is a selective, systemic and post emergent herbicide used to eradicate grasses and broad leaf weeds. Bispyribac sodium is also an acetolactate synthase (ALS or known as AHAS) inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 125401-92-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B0869A. | |
| Bis-Tos-PEG4 | Bis-Tos-PEG4 (PROTAC Linker 16) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PROTAC Linker 16. CAS No. 37860-51-8. Pack Sizes: 50 g; 100 g. Product ID: HY-W004816. | |
| Bistrifluron | Bistrifluron has insecticidal effects on the larval stage, and also has an effect on adult longevity, reproduction, and hatchability. Bistrifluron is used for the control of a variety of Lepidopterous pests [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 201593-84-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-119902. | |
| Bis(trimethylsilyl)acetylene | Bis(trimethylsilyl)acetylene is a biochemical reagent that can be used as a biological material or organic compound for life science related research [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 14630-40-1. Pack Sizes: 5 g; 10 g. Product ID: HY-W016961. | |
| Bis-Tris | Bis-Tris is an amine buffer suitable for protein and nucleic acid systems with a pH buffer range of 5.8-7.2. Bis-Tris can also be mixed with HEPES and cacodylic acid buffer to create a pH 8 environment and monitor fluorescence emission intensity at 305 nm. Gels formulated with Bis-Tris also avoid protein degradation in samples prepared at higher pH (pH 8.5) [1] [2] [3]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 6976-37-0. Pack Sizes: 25 g; 50 g. Product ID: HY-D0856. | |
| Bis-Tris hydrochloride | Bis-Tris hydrochloride is a biological buffer , and can be used in gel electrophoresis separations, cell culture and bioprocessing applications [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 124763-51-5. Pack Sizes: 10 g; 25 g. Product ID: HY-W105681. | |
| Bis-tris propane | Bis-tris propane (BTP) is a water-soluble buffer substance. Bis-tris propane can be used as a suitable buffer for polymerase chain reaction (PCR). Bis-tris propane can enhance the stability or activity of restriction enzymes [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: BTP. CAS No. 64431-96-5. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g; 10 g. Product ID: HY-126399. | |
| Bis(tri-tert-butylphosphine)palladium(0) | Bis(tri-tert-butylphosphine)palladium(0) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 53199-31-8. Pack Sizes: 250 mg; 1 g. Product ID: HY-W010772. | |
| BIT-225 | BIT-225 is an inhibitor for Vpu protein through block of Vpu ion channel, and thus inhibits the release of HIV-1 , especially in monocyte-derived macrophages ( EC 50 is 2.25 μM), without significant cytotoxicity (TC 50 is 284 μM) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 917909-71-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106282. | |
| Bithionol | Bithionol is an antibacterial, anthelmintic, and algaecide agent. Bithionol is also a potent inhibitor of soluble adenylyl cyclase through binding to the allosteric activator site (IC 50 : 4 μM) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 97-18-7. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-17592. | |
| Bitolterol mesylate | Bitolterol mesylate (WIN 37284) is a diester-type agonist amine bronchodilator without significant cardiac side effects [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Win 32784; Bitolterol methanesulfonate; S-1540 mesylate. CAS No. 30392-41-7. Pack Sizes: 5 mg. Product ID: HY-16103. | |
| Bitopertin | Bitopertin is a potent, noncompetitive glycine reuptake inhibitor, inhibits glycine uptake at human GlyT1 with a concentration exhibiting IC50 of 25 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RG1678; RO4917838. CAS No. 845614-11-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10809. | |
| Bivalirudin | Bivalirudin, a peptide anticoagulant, is a direct thrombin inhibitor for anticoagulation in the setting of invasive cardiology, particularly percutaneous coronary intervention [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 128270-60-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P1929. | |
| Bivalirudin TFA | Bivalirudin TFA is a synthetic 20 residue peptide which reversibly inhibits thrombin. Uses: Scientific research. Group: Peptides. CAS No. 1191386-55-6. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15664. | |
| Bivamelagon | MC-4R Agonist 2 (Example 1) is a MC4R agonist. MC-4R Agonist 2 can be used in the study of obesity, diabetes, inflammation, and erectile dysfunction [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MC-4R Agonist 2. CAS No. 2641595-54-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-153660. | |
| Bivatuzumab | Bivatuzumab (Anti-CD44 Recombinant Antibody; BIWA 4) is a humanized monoclonal antibody directed against CD44v6. CD44v6 could acts as a sarcoma target for CAR-redirected CIK cells [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BIWA 4; Anti-CD44 Recombinant Antibody. CAS No. 214559-60-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99281. | |
| BIX-01294 | BIX-01294 is a reversible and highly selective G9a and GLP Histone Methyltransferase inhibitor, with IC50s of of 1.7 ?M and 0.9 ?M, respectively. BIX-01294 inhibits G9a/GLP by competing for binding with the amino acids N-terminal of the substrate lysine residue. BIX-01294, a (1H-1,4-diazepin-1-yl)-quinazolin-4-yl amine derivative, induces necroptosis and autophagy. BIX-01294 has antitumor activity in recurrent tumor cells[1][2][3][4][5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 935693-62-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-10587. | |
| BIX-01338 hydrate | BIX-01338 hydrate is a histone lysine methyltransferase inhibitor. Uses: Scientific research. Group: Signaling pathways. CAS No. 1228184-65-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12991A. | |
| BIX02189 | BIX02189 is a potent and selective MEK5 inhibitor with an IC50 of 1.5 nM. BIX02189 also inhibits ERK5 catalytic activity with an IC50 of 59 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1265916-41-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12056. | |
| BIX 02565 | BIX 02565 is a potent ribosomal S6 kinase 2 (RSK2) inhibitor with IC50 of 1.1 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1311367-27-7. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16104. | |
| Bixin | Bixin (BX), isolated from the seeds of Bixa orellana , is a carotenoid, possessing anti-inflammatory, anti-tumor and anti-oxidant activities. Bixin treatment ameliorated cardiac dysfunction through inhibiting fibrosis, inflammation and reactive oxygen species ( ROS ) generation [1]. Uses: Scientific research. Group: Natural products. CAS No. 6983-79-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N6884. | |
| BJE6-106 | BJE6-106 (B106) is a potent, selective 3rd generation PKC? inhibitor with an IC50 of 0.05 ?M and targets selectivity over classical PKC isozyme PKC? (IC50=50 ?M). BJE6-106 (B106) induces caspase-dependent apoptosis. BJE6-106 (B106) possesses tumor-specific effect. Uses: Scientific research. Group: Signaling pathways. Alternative Names: B106. CAS No. 1564249-38-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-117800. | |
| BL-1249 | BL-1249 is a nonsteroidal anti-inflammatory agent (NSAID) and a potassium channel activator. BL-1249 potently activates K2P2.1 (TREK-1) and K2P10.1 (TREK-2) with EC50 values of 5.5 ?M and 8.0 ?M, respectively. BL-1249 extracellular application activates all TREK subfamily members but has no effect on other K2P subfamilies. BL-1249 exhibits more selective for the bladder (EC50 of 1.26 ?M) than vascular tissue (EC50 of 21.0 ?M)[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 18200-13-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-108596. | |
| BL-918 | BL-918 is an orally active UNC-51-like kinase 1 (ULK1) activator with an EC50 of 24.14 nM. BL-918 exerts its cytoprotective autophagic effect by targeting ULK complex. BL-918 has the potential for Parkinsons disease (PD) treatment[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2101517-69-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-124729. | |
| Blarcamesine | Blarcamesine is an orally bioavailable Sigma-1 receptor agonist and muscarinic receptor modulator, with anticonvulsant, anti-amnesic, neuroprotective and antidepressant properties. Blarcamesine ameliorates neurologic impairments in a mouse model of Rett syndrome [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 195615-83-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105296. | |
| Blarcamesine hydrochloride | Blarcamesine hydrochloride (Anavex 2-73) is a Sigma-1 Receptor agonist with an IC 50 of 860 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Anavex 2-73. CAS No. 195615-84-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-101864. | |
| BL-B01D1 | BL-B01D1 is a bispecific ADC, which targets EGFR and HER3 through bispecific antibody Izalontamab (HY-P99676), and exhibits cytotoxicity against various cancer cells via inhibition of DNA replication and DNA synthesis by its ADC toxin ED04 (HY-153891)[1]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-164702. | |
| Blebbistatin | Blebbistatin is a selective non-muscle myosin II (NMII) inhibitor, promotes directional migration of corneal endothelial cells (CECs) and accelerates wound healing, and better preserves cell junctional integrity and barrier function. Blebbistatin blocks cell migration [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 674289-55-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13813. | |
| (-)-Blebbistatin | (-)-Blebbistatin is a selective inhibitor of the ATPase activity of non-muscle myosin II [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 856925-71-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13441. | |
| (+)-Blebbistatin | (+)-Blebbistatin is the inactive enantiomer of ( - )-Blebbistatin. ( - )-Blebbistatin is a selective inhibitor of myosin II ATPase [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1177356-70-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107657. | |
| Bleomycin hydrochloride | Bleomycin hydrochloride is a DNA synthesis inhibitor. Bleomycin hydrochloride is a DNA damaging agent. Bleomycin hydrochloride is an antitumor antibiotic [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 67763-87-5. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17565A. | |
| Bleomycin sulfate | Bleomycin sulfate is a DNA synthesis inhibitor. Bleomycin hydrochloride is a DNA damaging agent. Bleomycin sulfate is an antitumor antibiotic [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Bleomycin sulfate. CAS No. 9041-93-4. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-17565. | |
| Bleselumab | Bleselumab (ASKP 1240) is a human anti- CD40 monoclonal antibody (mAb). Bleselumab binds to human CD40 with high affinity ( K d : 0.24 nM). Bleselumab inhibits immune responses by blocking the interaction of CD40 with its ligand CD40L. Bleselumab prevents organ transplant rejection [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ASKP 1240; Anti-Human CD40 Recombinant Antibody. CAS No. 1453067-91-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99257. | |
| Bleximenib | Bleximenib (JNJ-75276617; Menin-MLL inhibitor 24) is a potent, selective and orally active menin-KMT2A protein-protein interaction inhibitor with IC 50 values of 0.1, 0.045, ≤0.066 nM for human, mouse, dog, respectively. Bleximenib shows antiproliferative activity and induces apoptosis. Bleximenib has the potential for the research of Acute myeloid leukemia (AML) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JNJ-75276617; Menin-MLL inhibitor 24. CAS No. 2654081-35-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-148669. | |
| Bleximenib oxalate | Bleximenib (JNJ-75276617; Menin-MLL inhibitor 24) oxalate is a potent, selective and orally active menin-KMT2A protein-protein interaction inhibitor with IC 50 values of 0.1, 0.045, ≤0.066 nM for human, mouse, dog, respectively. Bleximenib oxalate shows antiproliferative activity and induces apoptosis. Bleximenib oxalate has the potential for the research of Acute myeloid leukemia (AML) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JNJ-75276617 oxalate; Menin-MLL inhibitor 24 oxalate. CAS No. 2866179-95-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148669A. | |
| Blinatumomab | Blinatumomab (Anatumomab) is a bispecific monoclonal antibody with two binding sites, one for CD3E on T cells and one for CD19 on B cells. Blinatumomab can be used in research for acute lymphoblastic leukemia [1] [2] [3] [4]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anatumomab. CAS No. 853426-35-4. Pack Sizes: 100 μg; 500 μg; 1 mg; 5 mg. Product ID: HY-P9963. | |
| Bliretrigine | Bliretrigine is a sodium channel blocker. Bliretrigine has the effect of relieving pain [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1233229-75-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145558. | |
| Blonanserin | Blonanserin (AD-5423) is a potent and orally active 5-HT 2A ( K i =0.812 nM) and dopamine D2 receptor ( K i =0.142 nM) antagonist. Blonanserin is usually acts as an atypical antipsychotic agent and can be used for the research of extrapyramidal symptoms, excessive sedation, or hypotension [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AD-5423. CAS No. 132810-10-7. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13575. | |
| Blosozumab | Blosozumab (LY2541546) is an anti-Human sclerostin (SOST) antibody inhibitor. Blosozumab stimulates bone formation and reduces bone resorption. Blosozumab can be used in the research of Osteoporosis [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1132758-87-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99186. | |
| BLT-1 | BLT-1, a thiosemicarbazone copper chelator, is a selective scavenger receptor B, type 1 (SR-BI) inhibitor. BLT-1 inhibits the transfer of lipids between high-density lipoproteins (HDL) and cells mediated by SR-BI. BLT-1 is a potent HCV entry inhibitor[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Block lipid transport-1. CAS No. 321673-30-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-116767. | |
| BLU0588 | BLU0588 is an orally active, potent and selective PRKACA (protein kinase cAMP-activated catalytic subunit alpha) kinase inhibitor, with an IC50 of 1 nM and dissociation constant (Kd) of 4 nM. BLU0588 can be used for fibrolamellar carcinoma (FLC) research[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2810747-78-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-153967. | |
| BLU2864 | BLU2864 is an orally active, highly selective, ATP-competitive PRKACA inhibitor (IC50=0.3 nM). BLU2864 shows anti-tumor activity. BLU2864 can be used in cancer and polycystic kidney disease research[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2810747-89-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150076. | |
| BLU-945 | BLU-945 is a potent, highly selective, reversible and orally active epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKIs). BLU-945 can effectively inhibit EGFR with L858R and/or exon 19 deletion mutation, T790M mutation and C797S mutation. BLU-945 can be used for the research of lung cancer including non-small cell lung cancer (NSCLC) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZL-2313. CAS No. 2660250-10-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-144680. | |
| BLU9931 | BLU9931 is a potent, highly selective, and irreversible fibroblast growth factor receptor 4 (FGFR4) inhibitor with an IC50 of 3 nM and a Kd of 6 nM. BLU9931 has significant antitumor activity[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1538604-68-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-12823. | |
| Blumeatin | Blumeatin, isolated from Blumea balsamifera DC, could protect liver against injury induced by CCl4 and thioacetamide (TAA) [1]. Uses: Scientific research. Group: Natural products. CAS No. 118024-26-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N2358. | |
| BM-1244 | BM-1244 (APG-1252-M1) is a Bcl-xL/Bcl-2 inhibitor with Kis of 134 nM and 450 nM. BM-1244 has anti-tumor effects by inducing apoptosis and suppressing tumor growth. BM-1244 can induce cytochrome C and Smac release from mitochondria with caspase-3 and PARP cleavage. BM-1244 exhibits synergy with chemotherapy in vivo. BM-1244 can be studied in research for colorectal cancer, acute myeloid leukemia and gastric cancer[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: APG-1252-M1. CAS No. 1619923-32-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-138832. | |
| BM213 | BM213, a potent and selective agonist for C5aR1, shows antitumor activity in a mouse model of mammary carcinoma. Uses: Scientific research. Group: Peptides. CAS No. 2891606-02-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-145237. | |
| BM635 | BM635 is a MmpL3 inhibitor with outstanding anti-mycobacterial activity. BM635 has an MIC 50 of 0.12 μM against M. tuberculosis H37Rv. Uses: Scientific research. Group: Signaling pathways. CAS No. 1493762-74-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109587. | |
| BM-962 | BM-962 (Compound 31) is a potent small-molecule inhibitor of Bcl-2 with an IC 50 value of 4 nM ( K i =0.8 nM) and Bcl-xL with an IC 50 value of 3.9 nM ( K i <1 nM). BM-962 inhibits the cell growth in H1417 and H146 cell lines with IC 50 values of 9 and 13 nM, respectively. BM-962 is promising for research of cancers [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1391107-57-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-169925. | |
| BMF-219 | Menin-MLL inhibitor 21 (example 9) is a specific, irreversible inhibitor of Menin-MLL interaction, useful for the study of autoimmune diseases, heteroimmune diseases, cancer, and other diseases dependent on menin-MLL. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Menin-MLL inhibitor 21. CAS No. 2448172-22-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150105. | |
| BMH-21 | BMH-21 is a first-in-class DNA intercalator which inhibits RNA polymerase I ( Pol I ) transcription. BMH-21 possesses anticancer activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 896705-16-1. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-12484. | |
| BML-277 | BML-277 is a selective checkpoint kinase 2 (Chk2) inhibitor with an IC50 of 15 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Chk2 Inhibitor II. CAS No. 516480-79-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13946. | |
| BML-278 | BML-278 is a SIRT1 activator ( EC 150 : 1 μM). BML-278 increases H3K9 methylation and inhibits H3K9 acetylation in both the paternal and maternal pronucleus. BML-278 improves early embryonic development. BML-278 arrests the cell cycle at the G1/S phase, and reduces senescence in primary human mesenchymal cells. BML-278 reduces tubulin acetylation in U937 cells. BML-278 also increases mitochondrial density in murine C2C12 myoblasts [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 120533-76-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W025074. | |
| BML-284 | BML-284 is a potent and cell-permeable Wnt signaling activator. BML-284 induces TCF-dependent transcriptional activity with an EC50 of 700 nM[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 853220-52-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-19987. | |
| BMPO | BMPO (BocMPO) is a cell-permeable superior spin trap with favorable chemical and spectroscopic features. BMPO (BocMPO) can be used for detecting thiyl radicals, hydroxyl radicals, superoxide anions and glutathiyl radicals [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BocMPO. CAS No. 387334-31-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121137. | |
| BMPS | BMPS is a nonclaevable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Uses: Scientific research. Group: Signaling pathways. CAS No. 55750-62-4. Pack Sizes: 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-42146. | |
| BMP signaling agonist sb4 | BMP signaling agonist sb4 is a potent benzoxazole bone morphogenetic protein 4 (BMP4) signaling agonist with a EC50 value of 74 nM, activates BMP signaling by stabilizing intracellular p-SMAD-1/5/9. BMP signaling agonist sb4 activates BMP4 target genes (inhibitors of DNA binding,?Id1?and?Id3) canonical BMP signaling[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 100874-08-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-124697. | |
| BMS-1 | BMS-1 is an inhibitor of the PD-1/PD-L1 protein/protein interaction (IC50 between 6 and 100 nM)[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PD-1/PD-L1 inhibitor 1. CAS No. 1675201-83-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19991. | |
| BMS-1166 | BMS-1166 is a potent PD-1/PD-L1 immune checkpoint inhibitor. BMS-1166 induces dimerization of PD-L1 and blocks its interaction with PD-1, with an IC50 of 1.4 nM. BMS-1166 antagonizes the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1818314-88-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-102011. | |
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