USBiological 4 - Products
Worldwide
Our biochemicals, antibodies, recombinant proteins, cell culture media and molecular biology kits are used in virtually all scientific applications.From affordable research quantities to larger bulk amounts.
| Product | Description | |
|---|---|---|
| Cadmium Fluoride | Cadmium fluoride is used as an insulator for ultra high speed mass telecommunications equipment. It is also used to prepare glass ceramics with desirable optical properties. Group: Biochemicals. Grades: Highly Purified. CAS No. 7790-79-6. Pack Sizes: 25g, 50g. Molecular Formula: CdF2, Molecular Weight: 150.41. US Biological Life Sciences. |  Worldwide |
| Calcioic Acid | Calcioic Acid is the end product of metabolism of Calcifediol (C125700), which is a metabolite of Vitamin D. Calcifedio is the main circulating form of vitamin D3, formed in the liver by hydroxylation at C-25. Group: Biochemicals. Grades: Highly Purified. CAS No. 76794-34-8. Pack Sizes: 100ug, 250ug. Molecular Formula: C23H34O3, Molecular Weight: 358.51. US Biological Life Sciences. | Worldwide |
| Calcium-activated Chloride Channel Inhibitor, CaCCinh-A01 | An aminothiophene that inhibits Calcium-activated Chloride Channel (CaCC) current influx induced by multiple calcium-elevating agonists (IC50=10uM) without inhibiting calcium elevation, and CaMKII and CFTR activity. Inhibits CaCC chloride response following agonist stimulation in human bronchial and intestinal epithelial cells. Also demonstrates an inhibitory effect on TMEM16A channels (IC50=2.1uM). Group: Biochemicals. Alternative Names: ANO Blocker I, Anoctamin Blocker I, TMEM16 Blocker I, 6-tert-butyl-2- (furan-2-carboxamido) -4, 5, 6, 7-tetrahydrobenzo [b]thiophene-3-carboxylic acid, CaCC Blocker I. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??NO?S, Molecular Weight: 347.43. US Biological Life Sciences. | Worldwide |
| Calcium Citrate Tetrahydrate | Calcium Citrate Tetrahydrate is used as the carbon source in the preparation of porous carbon without an activation process. Group: Biochemicals. Grades: Highly Purified. CAS No. 5785-44-4. Pack Sizes: 5g, 25g. Molecular Formula: C12H24Ca3O18, Molecular Weight: 576.54. US Biological Life Sciences. | Worldwide |
| Calcium Phenylpyruvate | Calcium Phenylpyruvate is synthesized by carbonylation of benzyl chloride via a multi-phase-catalyzed reaction and a useful compound to monitor the kinetics of carbonylation of benzyl chloride. It can also be used to investigate pepsin activity in vitro. Group: Biochemicals. Grades: Highly Purified. CAS No. 54865-40-6. Pack Sizes: 100ug, 250ug. Molecular Formula: C18H14Ca2O6, Molecular Weight: 406.46. US Biological Life Sciences. | Worldwide |
| Calcium Sulfate Hemihydrate | Calcium Sulfate Hemihydrate is prepared from the utilization and recycling byproduct, phosphogypsum (PG) as raw material. Group: Biochemicals. Alternative Names: Sulfuric acid calcium salt hemihydrate; Plaster of Paris. Grades: Highly Purified. CAS No. 10034-76-1. Pack Sizes: 50g, 100g, 250g, 500g. Molecular Formula: CaSO4 1/2H2O, Molecular Weight: 145.14. US Biological Life Sciences. | Worldwide |
| Calphostin C (UCN 1028C, PKF115-584, Cal-C) | Potent and highly specific cell permeable protein kinase C (PKC) inhibitor. The inhibition of PKC is light-dependent. PKA, PKG, DAG kinase, phospholipase D1 and D2, myosin light chain kinase and c-Src inhibitor. Anticancer compound. Inhibits cell proliferation and strongly induces apoptosis in vitro. Inducer of endoplasmic reticulum ER-stress. Shown to directly and potently block L-type Ca channels. Calphostin C specifically inhibits contraction-stimulated glucose transport but not insulin-stimulated glucose transport in skeletal muscle. Wnt/beta-catenin/lef-1 signaling inhibitor. beta-catenin/TCF antagonist. Inhibits Wnt-activated genes in a dose-dependent fashion. Source:Cladosporium cladosporioides sp. Group: Biochemicals. Grades: Highly Purified. CAS No. 121263-19-2. Pack Sizes: 100ug, 1mg. Molecular Formula: C44H38O14 , Molecular Weight: ~790.8. US Biological Life Sciences. | Worldwide |
| CaMKII Inhibitor XII (Ca2+/Calmodulin-Dependent Protein Kinase II Inhibitor XII) | A pyrimidinyl sulfonamide compound that acts as a potent, reversible and CaM non-competitive inhibitor of CaMKII activities (IC50 = 0.063uM) with excellent selectivity over several kinases (IC50 = >60, 36, 11, 30 and 21uM for CaMKIV, MLCK, p38alpha, Akt1 and PKC, respectively). Shown to exhibit ~25-fold greater potency towards CaMKII than the CaM-competitive inhibitor KN-93. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| cAMP (Cyclic Adenosine Monophosphate, Cyclic AMP, Adenosine 3'5'-cyclic Monophosphate) 99+% (HPLC) | Cyclic adenosine monophosphate (cAMP, cyclic AMP or 3'-5'-cyclic adenosine monophosphate) is a second messenger important in many biological processes. cAMP is derived from adenosine triphosphate (ATP) and used for intracellular signal transduction in many different organisms, conveying the cAMP-dependent pathway. Group: Biochemicals. Alternative Names: Cyclic AMP-3',5'; Adenosine-3':5'-cyclic monophosphoric acid; Adenosine 3',5'-cyclophosphoric acid. Grades: Highly Purified. CAS No. 60-92-4. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
| Cancer Hydrolase KIAA1363 Inhibitor, JW480 (2-Isopropylphenyl-2- (2-naphthyl) ethylcarbamate, AADACL1 Inhibitor, Arylacetamide Deacetylase-Like 1 Inhibitor, NCEH1 Inhibitor, Neutral Cholesterol Ester Hydrolase 1 Inhibitor) | A membrane-permeable, highly potent and selective inhibitor against the 2-acetyl MAGE (monoakylglycerol ether) hydrolase KIAA1363/AADACL1 of both human (IC50=12nM; PC3 lysate) and murine (IC50=20nM; brain membrane samples) origin, with no significant effect toward other PC3 or murine brain serine hydrolase activities, including HSL, FAAH, and AChE. Readily crosses blood-brain barrier in mice and effectively suppresses PC3-derived tumor growth in mice in vivo (by 56% on day 33; 80mg/kg/day; o.g.). Also inhibits blood carboxylesterase. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Carbazotic Acid | Picric Acid and other nitroaromatic compounds can be detected on surfaces and in seawater by using photoluminescent polysiloles. Group: Biochemicals. Grades: Highly Purified. CAS No. 88-89-1. Pack Sizes: 5g, 50g. Molecular Formula: C6H3N3O7, Molecular Weight: 229.1. US Biological Life Sciences. | Worldwide |
| Carbonic Anhydrase IX/XII Inhibitor (CAIX Inhibitor) | A cell permeable benzenesulfonamide Carbonic Anhydrase (CA) inhibitor that is selective for human hCA IX and hCA XII (Ki = 0.9nM and 5.7nM, respectively) against two other physiologically relevant hCA isoforms (Ki = 23.4nM and 15nM for hCA I and hCA II, respectively), as compared with another CA inhibitor AAZ (Ki = 250nM, 12nM, 25nM, and 5.7nM for hCA I, hCA II, hCA IX, and hCA XII, respectively). It is shown to effectively inhibit the formation of metastases by 4T1 breast cancer cells in a mouse model dose-dependently at pharmacologic concentrations of 15-45mg/kg. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Carbonic Anhydrase IX/XII Inhibitor II, U-104 (CAIX Inhibitor II) | A cell permeable ureido-sulfonamide Carbonic Anhydrase (CA) inhibitor that is selective for human hCA IX and hCA XII (KiEnM and 4.5nM, respectively) against two other physiologically relevant hCA isoforms (KiP80nM and 9640nM for hCA I and hCA II, respectively). It elicits anti-tumor growth effects dose-dependently from 19 to 38mg/kg in a mouse tumor growth model implanted with MDA-MB-231 LM2-4Luc+ cells, and demonstrates metastasis inhibition in a mouse metastasis model injected with 4T1 cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Carfentanil Citrate-d5 | Isotope labelled Carfentanil Citrate is a Fentanyl (F275000) analogue, an opioid receptor agonist. Analgesic agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 5mg. Molecular Formula: C30H33D5N2O10, Molecular Weight: 591.66. US Biological Life Sciences. | Worldwide |
| CARM1 Inhibitor (1-Benzyl-3, 5-bis- (3-bromo-4-hydroxybenzylidene) piperidin-4-one, 3,5-bis(3-Bromo-4-hydroxybenzylidene)-1-benzylpiperidin-4-one, Coactivator-Associated Arginine Methyltransferase 1 Inhibitor, PRMT Inhibitor V) | A cell-permeable (bis-benzylidene) piperidinone compound that acts as a selective inhibitor against CARM1/PRMT4 arginine methyltransferase activity (IC50=7.1uM with PABP1 as substrate). It inhibits PRMT3 only at much higher concentrations (by 70% and 62% with 100uM inhibitor using NPL3 or rpS2 as substrate, respectively), exhibiting little activity against PRMT1, PRMT5, PRMT6 (IC50>100uM), or four HKMTs (<20% inhibition against DOTL1, G9a, SET7, or Suv39H1 with 100uM inhibitor). Shown to inhibit PSA promoter-mediated reporter transcription in LNCaP cells in a dose-dependent manner (by 74% and 97%, respectively, with 4 and 6uM inhibitor). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Carnosic Acid (4aR,10aS)-5,6-Dihydroxy-7-isopropyl-1,1-dimethyl-1,3,4,9,10,10a-hexahydro-2H-phenanthrene-4a-carboxylic Acid, CA) | Carnosic acid is a diterpene compound exhibiting antioxidative, anticancer, anti-angiogenic, anti-inflammatory, anti-metabolic disorder, and hepatoprotective and neuroprotective activities. It modulates Akt/IKK/NF-B signaling by PP2A and induces intrinsic and extrinsic pathway mediated apoptosis in human prostate carcinoma PC-3 cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 25mg. Molecular Formula: C20H28O4, Molecular Weight: ~332.43. US Biological Life Sciences. | Worldwide |
| Casein Kinase II Inhibitor VIII (4- (2- (4-Methoxybenzamido) thiazol-5-yl) benzoic acid, CK2 Inhibitor VIII, DYRK1B Inhibitor, Flt-3 Inhibitor VII) | A cell-permeable thiazolamide compound that acts as a potent, reversible, and ATP-competitive inhibitor against casein kinase-2/CK2 (IC50=32 and 46nM against CK2a and CK2a', respectively), as well as DYRK1B and FLt-3 (82% and 76% inhibition, respectively, at 30nM), while diplaying reduced or little potency toward other targets in a 70-kinase panel selectivity profile study. Shown to effectively block the proliferation of a variety of cancer cells (IC50=2.6, 1.6, and 2.4uM, in A549, HCT116, and MCF-7 cultures, respectively). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Casein Kinase II Inhibitor XII, TBBz (4, 5, 6, 7-Tetra bromobenzimidazole, CYP24A1 inhibitor, TBBz, CK2 Inhibitor, TBBz) | A cell-permeable halogenated benzimidazole compound that acts as a selective and ATP competitive inhibitor of casein kinase II (CK2, Ki = 70nM for the active hetero-tetrameric form). However, its effect on free CK2a and CK2a' subunits is significantly reduced (Ki = 510 and 400nM, respectively). Reported to reduce viability and proliferation in HeLa, Jurkat, and HL-60 cells (at 25uM). Also shown to disrupt the promoter activity of CYP24A1 and down-regulates its endogenous and 1, 25-Vitamin D3 (1,25-D3)-induced expression in PC3 cells. Synergistically enhances the anti-tumor effect of 1, 25-D3 in a PC3 xenograft murine model. CAS No:577779-57-8. Group: Biochemicals. Grades: Highly Purified. CAS No. 577779-57-8. Pack Sizes: 20mg. Molecular Formula: C?H?Br?N?, Primary Target: CK2. US Biological Life Sciences. | Worldwide |
| Casein Kinase I Inhibitor III, PF-4800567 (CKI Inhibitor III, PF-4800567)(3-(3-Chlorophenoxymethyl)-1-(tetrahydropyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine, HCl) | A cell-permeable pyrazolopyrimidinyl amino compound that acts as a potent, ATP-competitive and reversible inhibitor of CKle with ~22-fold greater potency over CKld (IC50=32 and 711nM, respectively) and displays excellent selectivity among 50-kinases, with the only exception of EGFR (69% inhibition at 1uM). Shown to preferentially block PER3 (PERIOD3) nuclear translocation in COS7-GFP-PER3-CKle cells over CKld-transfected cells (IC50=0.13 and 2.65uM, respectively), and PER2 degradation in COS7-GFP-PER2-CKle cells. Unlike Casein Kinase I Inhibitor II, PF-670462, PF-4800567 exerts only marginal effect on circadian clock under similar conditions. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Casein Kinase I Inhibitor V, LH846 (N-(5-Chloro-6-methyl-1,3-benzothiazol-2-yl)-2-phenylacetamide)(N-(5-Chloro-6-methylbenzo[d]thiazol-2-yl)-2-phenylacetamide) | A cell-permeable benzothiazolo compound that acts a potent, selective, and reversible inhibitor of CKIg (IC50=290nM). Exhibits much reduced potency towards CKle and CKla isoforms (IC50=1.3 and 2.5uM, respectively). Does not affect the activity of CK2 or other kinases in a 59-protein kinase panel. Shown to block CKld-dependent period protein PER1 phosphorylation and diminish its proteasomal degradation in a dose-dependent manner. Also, shown to lengthen the circadian period in U2OS cells (10h at 8uM) without significantly affecting the amplitude of Per2-dLuc and Bmal1-dLuc rhythms. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Caspase-8 Inhibitor, Q-IETD-OPh (Q-IE(OMe)-TD(OMe)-OPh, Quinolyl-Ile-Glu(OMe)-Thr-Asp(OMe)-OPh) | A second-generation capase-8 inhibitor that is potent, cell permeable, irreversible and nontoxic. Group: Biochemicals. Grades: Purified. Pack Sizes: 3mg. US Biological Life Sciences. | Worldwide |
| Caspase-9 Inhibitor, Q-LEHD-OPh (Q-LE(OMe)-HD(OMe)-OPh, Quinolyl-Leu-Glu(OMe)-His-Asp(OMe)-OPh) | A second-generation capase-9 inhibitor that is potent, cell permeable, irreversible and nontoxic. Group: Biochemicals. Grades: Purified. Pack Sizes: 3mg. US Biological Life Sciences. | Worldwide |
| Caspase Family Group I, Active, Recombinant Set (Caspases-1,4,5), Caspase-1 | Caspase Family Group I, Active, Recombinant Set (Caspases-1,4,5), Caspase-1. Group: Molecular Biology. Pack Sizes: 25 units. US Biological Life Sciences. | Worldwide |
| Caspase Family Group I, Active, Recombinant Set (Caspases-1,4,5), Caspase-4 | Caspase Family Group I, Active, Recombinant Set (Caspases-1,4,5), Caspase-4. Group: Molecular Biology. Pack Sizes: 25 units. US Biological Life Sciences. | Worldwide |
| Caspase Family Group I, Active, Recombinant Set (Caspases-1,4,5), Caspase-5 | Caspase Family Group I, Active, Recombinant Set (Caspases-1,4,5), Caspase-5. Group: Molecular Biology. Pack Sizes: 25 units. US Biological Life Sciences. | Worldwide |
| CB1 Antagonist AM251 (N-(Piperidin-1-yl)-5-(4-iodophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide, AM 251) | A potent and highly selective antagonist for cannabinoid subtyre 1 (CB1) receptor. Affinity for CB1 (IC50 = 8nM, Ki = 7.49nM) is more than 306-fold higher than that for CB2 receptors. Has been used in a study to determine its interaction with hippocampal neurons to enhance spatial memory in mice. Group: Biochemicals. Grades: Highly Purified. CAS No. 183232-66-8. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| CB2 Agonist, JWH 015 ((2-Methyl-1-propyl-1H-indol-3-yl)-1-naphthalenylmethanone, JWH-015, JWH 015) | A potent and highly selective agonist for cannabinoid subtye 2 (CB2) receptor. Affinity for CB2 (Ki = 13.8nM) is more than 28-fold higher than that for CB1 (Ki = 383nM) receptors. Group: Biochemicals. Grades: Highly Purified. CAS No. 155471-08-2. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| CB2 Inverse Agonist, SR 144528 (5- (4- chloro- 3- methylphenyl)- 1- [(4- methylphenyl)methyl]- N- [(1S, 2S, 4R)- 1, 3, 3- trimethylbicyclo[2. 2. 1]hept- 2- yl]- 1H- pyrazole-3) | A selective inverse agonist for peripheral cannabinoid (CB2) receptors (Ki = 0.6nM and 400nM for CB2 and CB1 receptors, respectively). Has been used in studies related to control of pain initiation, suppression of inflammation, and immune activation. Group: Biochemicals. Grades: Highly Purified. CAS No. 192703-06-3. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| CBF beta-Runx1 Inhibitor II, Ro5-3335 ([7-chloro-5-(2-pyrryl)-3H-1,4 benzodiazapin-2-(H)-one], Ro53335, CBFalpha-CBFbeta Inhibitor II) | A cell-permeable benzodiazepine that suppresses CBFalpha/Runx1-CBFbeta transactivation activity (25uM; 293-0 cells) via direct bindings to both subunits of the heterodimeric transcription factor complex. Shown to inhibit oncogenic fusion CBFB-MYH11-, TEL-RUNX1-, and RUNX1-ETO-, dependent leukemia cells proliferation (IC50 = 1.1 to 21.7uM) in vitro and more effectively reduce peripheral blood c-kit+ population (300mg/kg/d via animal feed) than Cytarabine in a murine Cbfb-MYH11 leukemia model in vivo. Comparing to CBFbeta-Runx1 Inhibitor I, Ro5-3335 modulates the Runx1-CBFbeta heterodimer formation without completely disrupting the subunits interaction. Group: Biochemicals. Grades: Highly Purified. CAS No. 30195-30-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Cdc25 Inhibitor IV, NSC 95397 (2,3-Bis(2-hydroxyethylthio)-1,4-naphthalenedione, PTP Inhibitor XXIX) | A cell-permeable, para-naphthoquinone that has been reported to inhibit protein tyrosine phosphatase activity, including Cdc25 dual specificity phosphatase (Ki=32nM, 96nM, and 40nM for Cdc25A, -B, and -C, respectively) and blocks G2M transition in murine carcinoma cells. In addition, it is shown to inhibit S100A4 binding to myosin-IIA via covalent modification of cysteine residues, Cys81 and Cys86, in the target binding cleft (IC50=1.8uM). It demonstrates inhibitory activity against S100A4-mediated depolymerization of myosin-IIA filaments. Group: Biochemicals. Grades: Highly Purified. CAS No. 93718-83-3. Pack Sizes: 10mg. Molecular Formula: C??H??O?S?, Molecular Weight: 310.4. US Biological Life Sciences. | Worldwide |
| Cdc2-Like Kinase Inhibitor IV, KH-CB19 ((E)-Ethyl-3-(2-amino-1-cyanovinyl)-6,7-dichloro-1-methyl-1H-indole-2-carboxylate) | A cell-permeable N-methylindolyl-enaminonitrile compound that acts as a potent, non-ATP mimetic binding and reversible inhibitor of Clk1 and Dyk1A (IC50=19.7 and 55.2nM, respectively) with moderate to excellent selectivity over Clk3 (IC50=530nM) and against 71-kinases. Shown to suppress phosphorylation of Ser/Arg-rich (SR) proteins, regulate alternative splicing and lower both full-length and alternatively spliced human tissue factor isoforms much more efficiently than Cdc2-Like Kinase Inhibitor, TG003 in HMEC-1 cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??Cl?N?O?, Molecular Weight: 338.2. US Biological Life Sciences. | Worldwide |
| CDDO-Me (NSC 713200, Bardoxolone Methyl, BARD, Methyl-2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oate) | A cell-permeable, bioavailable synthetic oleanane triterpenoid compound with anti-inflammatory, anti-tumor and cytoprotective properties. Shown to significantly reduce the expression of several inflammatory mediators, including IL-6, IL-10, IL-12, TNFalpha, Mip1alpha and others. Reverses high fat diet-induced type 2 diabetes in C57BL/6 mice (3mg/kg) and improves glucose homeostasis and insulin sensitivity. Down-regulates lipogenic gene expression in hepatocytes. Exhibits anti-proliferative activity in osteosarcoma cells (IC50 = 800, 150, 330, and 170nM in HOB-c, KHOS, KHOSR2, and U2OS cells, respectively). Enhances the effectiveness of chemotherapeutic agents by inducing intrinsic mitochondrial-dependent apoptotic pathway. Reported to interact with multi cellular targets, namely, Nrf2-Keap1, IKK, JAK-STAT, PPARg, ErbB2, PTEN, mTOR and Arp3 and covalently modify active site Cys residue via Michael addition. Group: Biochemicals. Grades: Highly Purified. CAS No. 218600-53-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Cdk4 Inhibitor V (4-(((4-Hydroxy-5-propoxy-pyridin-2-ylmethyl)-amino)-methylene)-6-iodo-4H-isoquinoline-1,3-dione) | A cell-permeable pyridinylmethylamino-isoquinoline dione compound that acts as a potent, ATP-binding site targeting and reversible inhibitor of Cdk4/D1 activity with selectivity over Cdk2/E and Cdk1/B (IC50=0.03, 1.6 and 25.3uM, respectively). Shown to block the phosphorylation of Rb and induce growth arrest in HCT116 and MCF-7 cells (IC50=0.73 and 0.88uM). Displays desirable metabolic stability in rat liver microsomes and in the presence of NADPH and UDPGA cofactors (t1/2 > 30mins). Group: Biochemicals. Grades: Highly Purified. CAS No. 943746-57-4. Pack Sizes: 5mg. Molecular Formula: C??H??IN?O?. US Biological Life Sciences. | Worldwide |
| Cefotaxime, Sodium Salt, High Purity, Cell Culture-Tested | Potent beta-lactamase-resistant antibiotic of cephalosporin class. Active against Gram-positive and Gram-negative organisms, including Gram-negative anaerobes. Inhibits cell wall synthesis. Group: Biochemicals. Alternative Names: (6R, 7R) -3-[ (Acetyloxy) methyl]-7-[[ (2Z) -2- (2-amino-4-thiazolyl) -2- (methoxyimino) acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4. 2. 0]oct-2-ene-2-carboxylic Acid Sodium Salt; Cefotax; HR 756; Pretor; Tolycar. Grades: Cell Culture Grade. CAS No. 64485-93-4. Pack Sizes: 1g, 5g. US Biological Life Sciences. | Worldwide |
| Cell Proliferation Inducer, WS3 (N- (6- (4- (3- (4- ( (4- methyl piperazin-1-yl) methyl ) -3- (trifluoro methyl ) phenyl) ureido) phenoxy) pyrimidin-4-yl) cyclopropane carboxamide Hydrochloride) | A cell-permeable, diarylurea analog that can reversibly induce cell proliferation of primary retinal pigment epithelial (RPE) cells from rodents and from fetal and adult human donors (~25nM). Its action suggested to be mediated through Erb3 binding protein 1 (Ebp1). Non-proliferating RPE cells at passage 6 appear to respond well to WS3 treatment, whereas actively proliferating cells in passage 1 to 4 do not exhibit any increase in proliferation. These cells can differentiate into functional monolayer following WS3 withdrawal. However, WS3-expanded adult human RPE cells differentiate less effectively when compared to stem cell-derived RPE cells. The expanded RPE cells are shown to preserve vision when transplanted into rodent models of retinal degeneration. Also shown to induce proliferation of mouse R7T1 beta cells (EC50 = 74nM). Not reported to induce any genetic changes or tumorigenic events. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??F?N?O? HCl. US Biological Life Sciences. | Worldwide |
| Ceranib-2 (3- (3- (4-methoxyphenyl) acryloyl) -4-phenylquinolin-2 (1H) -one, Ceranib 2, Ceranib2) | A cell-permeable, potent inhibitor of ceramidase (IC50=28mM) with anti-proliferative and proapoptotic properties. Shown to block the proliferation of SKVO3, ovarian adenocarcinma cells (IC50=730nM) in the G2/M phase. When used in combination with paclitaxel, it increases tumor chemosentitvity and exhibits additive chemotherapeutic effects. Reduces tumor burden in Balb/c mice when administered intraperitoneally (20-50mg/kg) without affecting the total body weight. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??NO?, Molecular Weight: 381.4. US Biological Life Sciences. | Worldwide |
| Cetirizine Lactose Ester Hydrochloride Salt (Technical Grade). (α/ β-mixture, mixture of diastereomers) | Cetirizine Lactose Ester is a lactose adduct of Cetirizine (C281100). Group: Biochemicals. Grades: Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C33H45ClN2O13.HCl. US Biological Life Sciences. | Worldwide |
| CFTR Activator, Cact-A1 | A cell-permeable, non-toxic aminopyrazolocarbonitr i le compound that acts as a potent, selective, reversible and cAMP-independent activator of CFTR-dependent Cl- channel in airway epithelial cells (EC50 = 1.6uM in CFTR-expressing Fisher rat thyroid cells). Also shown to activate deltaF508-CFTR in primary CF-HBE cell cultures (EC50 = 3.5uM). Reported to directly bind to the same site as CFTRinh-172. Does neither elevate intracellular cAMP levels nor appear to have any requirement for cAMP agonist, such as forskolin. Shown to additively potentiate the G551D-CFTR Cl- current activated by forskolin with CFTR potentiator, VX-770. Exerts no effect on either Ca2+-activated Cl- channel (TMEM16A) or intracellular Ca2+ levels. Group: Biochemicals. Alternative Names: Cystic Fibrosis Transmembrane Conductance Regulator Activator, Cact-A1, 5-((Z)-2-(2-(Allyloxy)phenyl)-1-cyanovinyl)-3-amino-1H-pyrazole-4-carbonitrile, (Z)-3-(2-(2-(Allyloxy)phenyl)-1-cyanovinyl)-5-amino-1H-pyrazole-4-carbonitrile. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??N?O. US Biological Life Sciences. | Worldwide |
| CFTR Inhibitor-172 (CFTRinh-172, 3-[ (3-Trifluoromethyl) phenyl]-5-[ (4-carboxyphenyl) methylene]-2-thioxo-4-thiazolidinone) | A cell-permeable 2-thio-4-thiazolidinone compound that acts as a potent, reversible, rapid, and voltage-independent inhibitor of CFTR (cystic fibrosis transmembrane conductance regulator)-mediated Cl- transport in human airway cells (Ki ~300nM). It does not prevent elevation of cellular cAMP, nor does it inhibit non-CFTR Cl- channels, MDR-1, ATP-sensitive K+ channels, or a series of other transporters even at concentrations as high as 5uM. Shown to block cholera toxin-induced intestinal fluid secretion in mice. May be also useful for reducing intestinal fluid loss in other secretory diarrheas. Group: Biochemicals. Grades: Highly Purified. CAS No. 307510-92-5. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| CGP 35348 (GABAB Receptor Antagonist, CGP 35348, CGP35348, CGP-35348) | A selective antagonist of post-synaptic GABAB receptors (IC50 = 34uM) that can permeate the blood brain barrier. Exhibits about 10-fold lower affinity for pre-synaptic receptors. Blocks K+-evoked glycine exocytosis in mouse spinal cord and hippocampal nerve endings. Shown to antagonize the potentiating effect of L-baclofen on noradrenaline-induced stimulation of adenylate cyclase in rat cortex slices. Group: Biochemicals. Grades: Highly Purified. CAS No. 123690-79-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| CGP 37849 ((E)-(±)-2-Amino-4-methyl-5-phosphono-3-pentenoic Acid) | A highly potent competitive antagonist selective fornMDA receptors (Ki = 35nM). Biologically viable admitted orally or systematically. Widely used in studies of epilepsy, schizophrenia, depression, stress and anxiety related mental disorders. Group: Biochemicals. Grades: Highly Purified. CAS No. 127910-31-0. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| CGP 7930 (GABA B Receptor Antagonist, CGP7930, CGP 7930, CGP-7930) | A blood brain barrier permeable, positive allosteric modulator of the metabotropic GABAB receptor. Shown to modulate GABAB receptor in the high affinity state and thereby increases agonist affinity for the receptor. Also enhances agonist potency and efficacy even on recombinant GABAB receptors. Exhibits anxiolytic effects in rodents. Group: Biochemicals. Grades: Highly Purified. CAS No. 57717-80-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Chaetoglobosin A (NSC366739, BRN1097707) | Antibiotic. Cytochalasin analog with anti-fungal activity. Phytotoxic and anti-bacterial activity. Exhibits cytotoxic effects against human cancer cell lines. Enhances fibrinolytic activity of bovine aortic endothelial cells. Mycotoxin. Group: Biochemicals. Grades: Highly Purified. CAS No. 50335-03-0. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| Chaetoviridin A (CCRIS 7226) | Azaphilone antibiotic. Antifungal compound (phytopathogenic fungi). Cholesteryl ester transfer protein (CETP) inhibitor. Improves blood lipid levels. Monoamine oxidase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 128252-98-2. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| Chalcomycin (Aldgamycin D, NSC 150439) | 16-membered macrolide antibiotic. Broad spectrum antimicrobial. Antibacterial and antifungal. Protein biosynthesis inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 20283-48-1. Pack Sizes: 500ug, 1mg. US Biological Life Sciences. | Worldwide |
| Chartreusin (Lambdamycin) | Antibiotic. Antitumor compound. Topoisomerase II inhibitor. Induces single-strand scission in DNA in the presence of reducing agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 6377-18-0. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Chitin | Chitin. Group: Molecular Biology. CAS No. 1398-61-4. Pack Sizes: 25g, 250g. Molecular Formula: C30H50N4O19. US Biological Life Sciences. | Worldwide |
| Chitosan(200-600mPa.s, 0.5% in 0.5% Acetic Acid at 20deg C) | Chitosan(200-600mPa.s, 0.5% in 0.5% Acetic Acid at 20deg C). Group: Molecular Biology. CAS No. 9012-76-4. Pack Sizes: 25g, 500g. US Biological Life Sciences. | Worldwide |
| Chlorendic Anhydride | Chlorendic Anhydride is a chlorinated hydrocarbon used in the synthesis of unsaturated polyester resins. It is also an environmental pollutant. Chlorinated Reactive flame retardant Intermediate. Group: Biochemicals. Grades: Highly Purified. CAS No. 115-27-5. Pack Sizes: 100g, 500g. Molecular Formula: C9H2Cl6O3, Molecular Weight: 370.83. US Biological Life Sciences. | Worldwide |
| Chlorodibromoacetalde hyde (>90%) | Chlorodibromoacetalde hyde is used analytical studies in determining carbon, chlorine, and bromine content in chlorinated drinking water and humic acid via gas chromatography. Group: Biochemicals. Grades: Highly Purified. CAS No. 64316-11-6. Pack Sizes: 50mg, 250mg. Molecular Formula: C2HBr2ClO; (H2O). US Biological Life Sciences. | Worldwide |
| Chloro-methyl-phenyl-vinylsilane | Chloro-methyl-phenyl-vinylsilane is a reagent in the preparation of α-silylcarboxylic acids, and photosensitive benzocyclobutene-functionalized siloxane thermosets. Group: Biochemicals. Grades: Highly Purified. CAS No. 17306-05-7. Pack Sizes: 250mg, 1g. Molecular Formula: C9H11ClSi, Molecular Weight: 182.72. US Biological Life Sciences. | Worldwide |
| Chlorophenol Red Sodium Salt | Chlorophenol Red sodium salt is a pH indicator with a transition interval from 4.8 - 6.4 (yellow to red). It can also be used in analytical reagent use and analytical study of entrapped indicators; effect of ionic liquid entrapment on chemical performance of pH indicator dopants in xerogel films. Group: Biochemicals. Grades: Highly Purified. CAS No. 123333-64-2. Pack Sizes: 10g, 25g. Molecular Formula: C19H12Cl2NaO5S, Molecular Weight: 446.26. US Biological Life Sciences. | Worldwide |
| Chlorpropham | Chlorpropham. Group: Biochemicals. Grades: Highly Purified. CAS No. 101-21-3. Pack Sizes: 250mg, 1g. Molecular Formula: C10H12ClNO2, Molecular Weight: 213.66. US Biological Life Sciences. | Worldwide |
| Choline Hydroxide in Methanol Solution | Choline Hydroxide acts as an efficient catalyst for the synthesis of trans-2,3-dihydrofuro[3,2-c]coumarins. Also, it is used to prepare aqueous two-phase systems (ATPS) with polypropylene glycol. Efficient basic ionic liquid catalyst for the synthesis of α-hydroxyphosphonates. Group: Biochemicals. Grades: Highly Purified. CAS No. 123-41-1. Pack Sizes: 10g, 25g. Molecular Formula: C5H15NO2, Molecular Weight: 121.18. US Biological Life Sciences. | Worldwide |
| Choline Kinase-a Inhibitor, CK37 (CK37, N-(3,5-dimethyl-dimethylphenyl)-2-[[5-(4-ethylphenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetamide) | A cell-permeable, non-Hemicholinium-3 derivative and choline-competitive choline kinase-a inhibitor. It is demonstrated to inhibit endogenous choline kinase activity, dose-dependently, between 1-10uM, and dose-dependently decrease phosphocholine concentrations, as well as levels of downstream choline metabolites, including phosphatidylcholine and phosphatidic acid in HeLa cells. At 10uM, it is also shown to attenuate MAPK and PI3K/AKT signaling, and disrupt the actin cytoskeleton and membrane ruffling, consistent with siRNA choline kinase-a transfection. This compound exhibits dose-dependent suppression of cell growth in six tumor cell lines (IC50=5-10uM), in vitro. Furthermore, it is shown to suppress tumor growth in a mouse model by 48% at 0.08mg/g daily dose for 8 days without obvious toxicity, in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 1001478-90-5. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Chromium Picolinate | Chromium Picolinate is used as a supplement in the treatment in diabetes, with a claimed ability to improve glucose metabolism. Group: Biochemicals. Grades: Highly Purified. CAS No. 14639-25-9. Pack Sizes: 2.5g, 5g. Molecular Formula: C18H12CrN3O6, Molecular Weight: 418.3. US Biological Life Sciences. | Worldwide |
| Chrysomycin A (Chrysomycin V, Virenomycin V) | Antibiotic. Topoisomerase II inhibitor. Mediates a unique cross-linking reaction between DNA and histidine H3. Anti-neoplastic. Photosensitizing compound. Antitumor compound against human cell lines. Group: Biochemicals. Grades: Highly Purified. CAS No. 82196-88-1. Pack Sizes: 250ug, 1mg. US Biological Life Sciences. | Worldwide |
| Chrysomycin B (Chrysomycin M, Virenomycin M) | Antibiotic. Topoisomerase II inhibitor. Mediates a unique cross-linking reaction between DNA and histidine H3. Anti-neoplastic. Photosensitizing compound. Antitumor compound against human cell lines. Less potent than chrysomycin A. Group: Biochemicals. Grades: Highly Purified. CAS No. 83852-56-6. Pack Sizes: 250ug, 1mg. US Biological Life Sciences. | Worldwide |
| CI-994 (4-(Acetylamino)-N-(2-aminophenyl)benzamide, Acetyldinaline, Gö 5549, PD 123654) | Cell-permeable. A histone deacetylase (HDAC) inhibitor (Ki values are 0.41, 0.75, >100 and >100um for HDAC1, HDAC3, HDAC6 and HDAC8 respectively). Displays significant antitumor activity in vitro and in vivo against a broad spectrum of murine and human tumor models. Group: Biochemicals. Grades: Highly Purified. CAS No. 112522-64-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Cinnabarinic Acid (2-Amino-3-oxo-3H-phenoxazine-1,9-dicarboxylic acid) | A partial, low-potency agonist highly selective for mGlu4 receptors (EC50 >100uM, no effect on other mGlu subtype receptors). Used in assessing the functional roles of mGlu4 receptors in a variety of research areas, such as excitotoxic cell death, apoptosis, neuroinflammation, inflammation, and neuroimmune communication. Group: Biochemicals. Grades: Highly Purified. CAS No. 606-59-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Cinnamtannin B-1 (Epicatechin- (4beta?8, 2beta?O?7)-epicatechin- (4alpha?8)-epicatechin, Cinnamtannin B1, CB1) | A-Type proanthocyanidine. Selective cytotoxic agent. Potent antioxidant. Lipid peroxidation inhibitor. Antidiabetic, with similar effects to insulin activity in adipogenesis. Free radical scavenger. Antithrombotic. Inhibits platelet aggregation. Apoptosis inhibitor. Reduces intracellular Ca(2+) overload and ROS production. Antibacterial. Cyclooxygenase-2 (COX-2) inhibitor in vitro. LDL oxidation inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 88082-60-4. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Cinnamylamine Hydrochloride | Cinnamylamine Hydrochloride, can be used for the preparation of Tranylcypromine, a drug that acts as a nonselective and irreversible inhibitor of the enzyme monoamine oxidase (MAO), and is used as an antidepressant and anxiolytic agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 5586-89-0. Pack Sizes: 25mg, 100mg. Molecular Formula: C9H12ClN, Molecular Weight: 169.65. US Biological Life Sciences. | Worldwide |
| CIQ ((3-Chlorophenyl) [3, 4-dihydro-6, 7-dimethoxy-1- [ (4-methoxyphenoxy) methyl] -2 (1H) -isoquinolinyl] methanone) | A positive allosteric modulator selective for NR2C/D containingnMDA receptors (EC50 = 2.7 and 2.8uM for NR2C and NR2D, respectively). Increases channel opening frequency of recombinant NR2C/D containingnMDA receptors by two-fold without altering mean open time or EC50 values for glutamate or glycine bindings. No effect on NR2A or NR2B subtypes. Group: Biochemicals. Grades: Highly Purified. CAS No. 486427-17-2. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| cis-4-Heptenal | cis-4-Heptenal is an unsaturated aldehyde that possesses a fishy aroma. cis-4-Heptenal is a product of oxidative breakdown of fats in fish, and is naturally found in fish oils. Group: Biochemicals. Grades: Highly Purified. CAS No. 6728-31-0. Pack Sizes: 5g, 25g. Molecular Formula: C7H12O. US Biological Life Sciences. | Worldwide |
| Cisatracurium-d6-20-methyl Dibenzenesulfonate | Cisatracurium-d6-20-methyl Dibenzenesulfonate is the labeled analog of Cisatracurium-20-methyl Dibenzenesulfonate (C496705), an impurity of Cisatracurium (C496700), an enantiomer of Atracurium Besylate (A794500), a neuromuscular blocking agent. It could be used in liver transplant patient with safety. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C66H78D6N2O18S2, Molecular Weight: 1263.54. US Biological Life Sciences. | Worldwide |
| cis-Nerolidol | cis-Nerolidol is one of the main component in the essential oils from fresh aerial parts of Thymus ciliatus (Lamiaceae). Also, it is a terpene that displays high potency on the contractility of cardiac muscle in guinea pig left atrium. A potential and effective treatment for malaria. Group: Biochemicals. Grades: Highly Purified. CAS No. 3790-78-1. Pack Sizes: 1ml, 2.5ml. Molecular Formula: C15H26O, Molecular Weight: 222.37. US Biological Life Sciences. | Worldwide |
| cis-Zeatin | cis-Zeatin is a member of the cytokinin family. Group: Biochemicals. Grades: Highly Purified. CAS No. 32771-64-5. Pack Sizes: 10mg, 25mg. Molecular Formula: C10H13N5O, Molecular Weight: 219.24. US Biological Life Sciences. | Worldwide |
| CJ-21058 ((5R, Z)-3-(Hydroxy((1R, 2S, 6S, 8aS)-1, 3, 6-trimethyl-2-((E)-prop-1-en-1-yl)-1, 2, 4a, 5, 6, 7, 8, 8a-octahydro-naphthalen-1-yl)methylene)-5-(hydroxymethyl)-1-methylpyrrolidine-2, 4-dione) | Antibiotic. SecA inhibitor. Antibacterial and antifungal. Cytotoxic. Methyl analog of equisetin. Group: Biochemicals. Grades: Highly Purified. CAS No. 405072-57-3. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| CL316243 Hydrate (Disodium 5- [ (2R) -2- [ [ (2R) -2- (3-Chlorophenyl) -2-hydroxyethyl] amino] propyl] -1, 3-benzodioxole-2, 2-dicarboxylate Hydrate) | A very potent agonist highly selective for beta-3 adrenoceptors (EC50 = 3nM). Widely used to assess the functional roles of beta-3 adrenoceptors in glucose homeostasis, thermogenesis, obesity, cardiac functions, retinal neurotoxicity, and tissue inflammation. Group: Biochemicals. Grades: Highly Purified. CAS No. 138908-40-4. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Cladospirone Bisepoxide (Palmarumycin C13, Diepoxin zeta, Antibiotic Sch53514) | Antibiotic. Antibacterial and antifungal. Antitumor compound. Germination inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 152607-03-9, 155866-40-3. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
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