USBiological 4 - Products
Worldwide
Our biochemicals, antibodies, recombinant proteins, cell culture media and molecular biology kits are used in virtually all scientific applications.From affordable research quantities to larger bulk amounts.
| Product | Description | |
|---|---|---|
| Clasto-Lactacystin beta-lactone (Omuralide) | In vitro lactacystin does not react with the proteasome. It rather undergoes a spontaneous conversion (lactonization) to the active metabolite clasto-lactacystin beta-lactone. Potent and selective irreversible and cell permeable proteasome inhibitor. Inhibits the chymotrypsin-like, trypsin-like and caspase-like peptidase activity of the proteasome. The active metabolite of lactacystin with higher potency since it does not require hydrolysis in order to become cell permeable. Calpain and cathepsin inhibitor. Apoptosis inducer. Anticancer compound. Induces differentiation and inhibits cell cycle progression in several tumor cell lines. Induces neuritogenesis. Autophagy inducer. Group: Biochemicals. Grades: Highly Purified. CAS No. 154226-60-5. Pack Sizes: 100ug. Molecular Formula: C10H15NO4, Molecular Weight: 213.2. US Biological Life Sciences. |  Worldwide |
| Clindamycin-13C,D3 | Clindamycin-13C,D3 is the labeled analog of Clindamycin (C580000, HCl salt), a semi-synthetic antibiotic prepared from Lincomycin. Antibacterial. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 5mg. Molecular Formula: C1713CH30D3ClN2O5S, Molecular Weight: 428.99. US Biological Life Sciences. | Worldwide |
| Cloperastine Hydrochloride | Cloperastine Hydrochloride is an anti-tussive drug as an over-the-counter cold medicine. Group: Biochemicals. Grades: Highly Purified. CAS No. 14984-68-0. Pack Sizes: 10g, 25g. Molecular Formula: C20H24ClNO HCl, Molecular Weight: 329.863646. US Biological Life Sciences. | Worldwide |
| CMPDA (N,N'-1,4-Phenylenedi-2,1-ethanediyl bis-2-propanesulfonamide) | CMPDA (N,N'-1,4-Phenylenedi-2,1-ethanediyl bis-2-propanesulfonamide). Group: Biochemicals. Grades: Highly Purified. CAS No. 380607-77-2. Pack Sizes: 10mg. Molecular Formula: C16H28N2O4S2, Biological Activity: Positive allosteric modulator of GluR2 receptors (EC50 values are 45.4 and 63.4 nM at GluR2i and GluR2o respectively, in a calcium influx screening assay). Binds at the modulator binding pocket located at the interdimer interface and the clamshell hinges. US Biological Life Sciences. | Worldwide |
| c-Myc Inhibitor III, Mycro2 (5- (Thiophen-2-yl) -N- (thiophen-2-ylmethyl) -7- (trifluoromethyl) pyrazolo[1, 5-a]pyrimidine-2-carboxamide) | A cell-permeable pyrazolopyrimidine-carboxamide that selectively inhibits c-Myc-Max dimer DNA binding activity (IC50=23uM) by preventing c-Myc-Max heterodimer formation, while affecting Max, Jun, C/EBPa homodimers, or Jun-Fos heterodimer DNA binding only at much higher concentrations (IC50=>54uM). Shown to selectively inhibit c-Myc-Max-dependent transcription (by 77% against E-Box promoter-driven reporter transcription at 10uM), cancer proliferation, and anchorage-independent colony formation (Effective conc. 10-20uM). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| CNQX (6-Cyano-7-nitroquinoxaline-2,3-dione, 6-Cyano-2,3-dihydroxy-7-nitro-quinoxaline) | A potent and competitive antagonist for AMPA/kainate receptors (Ki = 0.6-2.11uM for GluA1-4 and Ki = 1.3-5.3uM for different subtypes of Kainate receptors) and a negative allosteric modulator atnMDA receptor glycine binding site. Widely used for assessing the functional roles of neurotransmission mediated by glutamate receptors in both normal and abnormal brain functions. Group: Biochemicals. Grades: Highly Purified. CAS No. 115066-14-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| CNS-1102 (N-(3-Ethylphenyl)-N-methyl-N'-1-naphthalenylguanidine Hydrochloride, Cerestat, Aptiganel Hydrochloride, NMDA Antagonist V) | A non-competitive, subunit non-selective, potent antagonist fornMDA receptors (IC50 = 0.13, 0.068, 0.087, and 0.14uM for NR2A - D, respectively). Widely used as neuroprotective agent after acute traumatic brain injury and stroke in animal researches. Group: Biochemicals. Grades: Highly Purified. CAS No. 137159-92-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Cocamidopropyl Betaine (~30% aqueous solution) | Cocamidopropyl Betaine is a medium strength surfactant. Group: Biochemicals. Grades: Highly Purified. CAS No. 86438-79-1. Pack Sizes: 5g, 10g. Molecular Formula: C19H38N2O3. US Biological Life Sciences. | Worldwide |
| Compound 112254 (4- (tert-Butyl) -N- (3- (4- (4-methoxybenzyl) piperazin-1-yl) -3-oxopropyl) benzamide) | Adiponectin receptor (AdipoR) agonist. Binds to AdipoR1 and AdipoR2 less potent than AdipoRon. Activates 5'-adenosine monophosphate-activated protein kinase (AMPK) in cultured mammalian cells. Improves diabetes, glucose and lipid metabolism and insulin sensitivity in cultured cells and in mice by AdipoR-dependent mechanisms. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Compound W (CW, 3,5-Bis(4-nitrophenoxy)benzoic acid) | Compound W is a y-secretase inhibitor that has been shown to lower the levels of secreted Ab42 and Nb25. Group: Biochemicals. Grades: Highly Purified. CAS No. 173550-33-9. Pack Sizes: 50mg, 250mg. US Biological Life Sciences. | Worldwide |
| Concanamycin A (Olimycin, Antibiotic TAN 1323B, Antibiotic X4357B) (High Purity) | Antibiotic. More potent and specific H+-ATPase inhibitor than bafilomycin A1. Inhibits acidification of organelles such as lysosomes and the Golgi apparatus. Blocks cell surface expression of viral glycoproteins without affecting their synthesis. Cytotoxic in a number of cell lines in a cell viability assay. Induces nitric oxide (NO) production. Autophagy inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 80890-47-7. Pack Sizes: 25ug, 100ug, 1mg. US Biological Life Sciences. | Worldwide |
| Concanamycin B (High Purity) (8-Deethyl-8-methylconcanamycin A) | Antibiotic. Exhibits similar activity as concanamycin A and concanamycin C. Specific vacuolar-type H+-ATPase inhibitor. Inhibitor of autophagic degradation by rising lysosomal pH and thus inactivating the lysosomal acid hydrolases. Suppresses bone resorption. Inhibits proliferation of mouse splenic lymphocytes. Antifungal and larvicidal. Group: Biochemicals. Grades: Highly Purified. CAS No. 81552-33-2. Pack Sizes: 25ug, 100ug, 500ug. US Biological Life Sciences. | Worldwide |
| Concanamycin C (4'-O-De (aminocarbonyl) concanamycin A) (High Purity) | Antibiotic. Vacuolar-type H+-ATPase inhibitor. Inhibitor of autophagic degradation by rising lysosomal pH and thus inactivating the lysosomal acid hydrolases. Anti-osteoporotic. Antiviral. Immunosuppressive. Antifungal and anti-yeast. Group: Biochemicals. Grades: Highly Purified. CAS No. 81552-34-3. Pack Sizes: 25ug, 100ug, 500ug. US Biological Life Sciences. | Worldwide |
| Copper Acetoarsenite (Technical Grade) | Copper Acetoarsenite has been used as a rodenticide and insecticide, and also as a pigment, despite its toxicity. It is also used as a blue colorant for fireworks. Group: Biochemicals. Grades: Purified. CAS No. 12002-03-8. Pack Sizes: 100mg, 1g. Molecular Formula: Cu (C2H3O2)2·3Cu (AsO2)2, Molecular Weight: 1013.79. US Biological Life Sciences. | Worldwide |
| Copper(II) Nitrate Hemipentahydrate | Copper(II) Nitrate Hemipentahydrate, may be employed as copper precursor for the preparation of thin film of Cu2ZnSnS4 (CZTS). Group: Biochemicals. Grades: Highly Purified. CAS No. 19004-19-4. Pack Sizes: 50g, 100g. Molecular Formula: Cu(NO3)2 · 2.5H2O, Molecular Weight: 232.59. US Biological Life Sciences. | Worldwide |
| Cortisol (Hydrocortisone) | Cortisol, or Hydrocortisone, is a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism. Group: Molecular Biology. Alternative Names: (11 β)-11,17,21-Trihydroxy-pregn-4-ene-3,20-dione; Cortisol; 11 β,17,21-Trihydroxypregn-4-ene-3,20-dione; 17-Hydroxycorticosterone; 17α-Hydroxycorticosterone; NSC 10483. Grades: Highly Purified. CAS No. 50-23-7. US Biological Life Sciences. | Worldwide |
| CP-101,606 (Traxoprodil, CP-101606, (1S,2S)-1-(4-hydroxy-phenyl)-2-(4-hydroxy-4-phenylpiperidino)-1-propanol, NMDA Antagonist VI) | A highly selective antagonist for NR2B subunit containing nMDA receptors (IC50 = 0.039uM for NR2B and >100uM for NR2A, NR2C, and NR2D). Widely used as neuroprotective, analgesic, antidepressant, and anti-Parkinsonian agent in research. Group: Biochemicals. Grades: Highly Purified. CAS No. 134234-12-1. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| CPCCOEt ((E)-Ethyl 1, 1a, 7, 7a-tetrahydro-7- (hydroxyimino) cyclopropa[b]chromene-1a-carboxylate, mGlu1 Antagonist, CPCCOEt) | A potent, negative allosteric modulator selective for mGlu1 receptors (IC50 = 6.5uM). No effect on other mGlu subtype receptors and ionotropic glutamate receptors at concentrations less than 100uM. Acts by inhibiting an intramolecular interaction between the agonist-bound extracellular domain and the transmembrane domain. Widely used for studies related to peripheral pain and central pain pathways. Group: Biochemicals. Grades: Highly Purified. CAS No. 179067-99-3. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| C-Peptide (Hyperproinsulinemia, Insulin Precursor, Proinsulin), Positive Control | C-Peptide (Hyperproinsulinemia, Insulin Precursor, Proinsulin), Positive Control. Group: Molecular Biology. Pack Sizes: 15ul. US Biological Life Sciences. | Worldwide |
| CRAC Channel Inhibitor III, Pyr6 (N-(4-(3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl)phenyl)-3-fluoroisonicotinamide) | A cell-permeable pyrazole derivative that acts as a selective blocker of Stim1 and Orai1-coupled CRAC (Ca2+ release-activated Ca2+) channel-mediated SOCE (store-operated Ca2+ entry) in RBL-2H3 cells (IC50 = 490nM by Fura-2), while exhibiting much reduced potency against the transient receptor potential cation channel TRPC3-medated ROCE (receptor-operated Ca2+ entry) upon carbachol stimulation in TRPC3-expressing HEK293 cells (IC50 = 18.46uM; by Fura-2). A great complement to Pyr2, Pyr3, and Pyr10 in Ca2+ signaling studies. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H?F?N?O, Primary Target: Orai3. US Biological Life Sciences. | Worldwide |
| Creatine-(methyl-d3) Monohydrate | Creatine-(methyl-d3) Monohydrate is an isotopic analog of Creatine Monohydrate (6020-87-7), which is a nitrogenous organic acid that occurs naturally in vertebrates. Its main role is to facilitate recycling of Adenosine Triphosphate (ATP), the energy currency of the cell, primarily in muscle and brain tissue. Group: Biochemicals. Grades: Highly Purified. CAS No. 284664-86-4. Pack Sizes: 25mg, 50mg. Molecular Formula: C4H6D3N3O2 H2O. US Biological Life Sciences. | Worldwide |
| Cripto, FRL1, Cryptic Family 1 (CFC1) Recombinant, Human, Unstained Protein Molecular Weight Marker | Cripto, FRL1, Cryptic Family 1 (CFC1) Recombinant, Human, Unstained Protein Molecular Weight Marker. Group: Molecular Biology. Grades: Highly Purified. Pack Sizes: 15ul. US Biological Life Sciences. | Worldwide |
| CRM1 Inhibitor III (Chromosome Region Maintenance 1 Protein Inhibitor III, (Z)-But-2-enedioic acid (4-bromophenyl)amide (3-chlorophenyl)amide, Exportin 1 Inhibitor III, XPO1 Inhibitor III) | A cell-permeable butenediamide compound that acts as a potent, active site cysteine reactive irreversible inhibitor of CRM1/exportin 1. Shown to selectively repress agonist-mediated nuclear export of HDAC4/5, Rev and NFAT proteins in neonatal rat ventricular myocytes (NRVMs; EC50=2.2 and 3.5nM for GFP-HDAC5 and GFP-HIV Rev) and suppress hypertrophic growth of NRVMs (EC50=52nM for ANF expression inhibition) with negligible effect either on the phosphorylation of HDAC5 or on the kinase activities of P and CaMKII at 1uM. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??BrClN?O?. US Biological Life Sciences. | Worldwide |
| CRM1 Inhibitor IV, KPT-251 (KPT251, (Z) -2- (2- (3- (3, 5-bis (trifluoromethyl) phenyl) -1H-1, 2, 4-triazol-1-yl) vinyl) -1, 3, 4-oxadiazole, Exportin 1 Inhibitor IV, Chromosome Region Maintenance 1 Protein Inhibitor IV, CRM1 Inhibitor IV, XPO1 Inhibitor IV) | A cell-permeable, irreversible, triazole-containing heterotricyclic CRM1 inhibitor that effectively blocks CRM1-mediated nuclear export (4h 1uM in U2OS cells) via covalent interaction with CRM1 NES- (nuclear export signal) binding groove cysteine (Cys528 in human). Exhibits antileukemic activity against primary human CD19+ CLL (IC50 <500nM) via apoptosis induction even in the presence of stroma cells or other known CLL survival stimuli, while exhibiting little cytotoxicity toward CD56+ NK cells from healthy donors (1uM; up to 72h). Reported to prolong the survival of SCID mice (75mg/kg p.o.) engrafted with murine E-mu-TCL1 or human MV4-11 leukemia in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C??H?F?N?O. US Biological Life Sciences. | Worldwide |
| CTAP (Mu Opioid Receptor Antagonist, CTAP) | A highly potent octapeptide that acts as a selective and brain penetrating bioavailable u opioid receptor antagonist (IC50 = 3.5nM). Used in studies of reward systems and additions. Group: Biochemicals. Grades: Highly Purified. CAS No. 103429-32-9. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| CTOP (Mu Opioid Receptor Antagonist, CTOP) | A potent antagonist highly selective for Mu opioid receptor (Ki = 0.96nM for u receptor and > 10,000nM for delta receptors). Often used for studying the functional roles of Mu opioid receptors in both central and peripheral nervous systems. Group: Biochemicals. Grades: Highly Purified. CAS No. 103429-31-8. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Cubenol | Cubenol was used for biological study of antioxidant and antimicrobial activity and comparison of cinnamon leaf and bark essential oils and oleoresins. Cubenol was one of the major components of essential oils isolated from the aerial parts of Artemisia absinthium, Artemisia santonicum and Artemisia spicigera. Group: Biochemicals. Grades: Highly Purified. CAS No. 21284-22-0. Pack Sizes: 10mg, 50mg. Molecular Formula: C15H26O, Molecular Weight: 222.37. US Biological Life Sciences. | Worldwide |
| CUDC-101 (7-((4-((3-ethynylphenyl)amino)-7-methoxyquinazolin-6-yl)oxy)-N-hydroxyheptanamide) | A potent multitargeted inhibitor of histone deacetylase (HDAC) and the receptor kinases epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), with IC?? values of 4.4, 2.4, and 15.7nm, respectively. Displays potent antiproliferative and proapoptotic activities against cultured and implanted tumor cells that are sensitive or resistant to several approved single-targeted drugs. Group: Biochemicals. Grades: Highly Purified. CAS No. 1012054-59-9. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. | Worldwide |
| Curvulin (Ethyl 2- (2-acetyl-3, 5-dihydroxyphenyl) acetate) | Phytotoxin. Microtubule assembly inhibitor. Similar to curvularin. Group: Biochemicals. Grades: Highly Purified. CAS No. 19054-27-4. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Cuspin-1 ( (5-Bromo-3-pyridinyl) (4-methylphenyl) methanone, Survival Motor Neuron Protein Upregulator, Cuspin-1) | A cell-permeable pyridinylphenyl-methanone compound that is reported to effectively upregulate SMN (survival of motor neuron) protein level in 3 out of 4 SMA (spinal muscular atrophy) patient-derived fibroblast lines (by 71% to 93% increase in 48h; 5ug/ml), but not HT1080, 293T, A549, two human ESC-MN lines, MEF, mESC-MN, rat PC12, or rat ST14A cells. Shown to preferentially stimulate cellular Erk (Thr202/Tyr204) over Akt (Ser473) phosphorylation in SMA fibroblast line 9677 in a time-dependent manner (tmax = 24h; 10ug/ml), indicative of Ras-Raf-MEK signaling pathway activation. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. Molecular Formula: C??H??BrNO. US Biological Life Sciences. | Worldwide |
| CX546 (AMPA Positive Allosteric Modulator, CX546, CX-546, CX 546) | A positive allosteric modulator selective for the AMPA receptors. Used in studies related to Schizophrenia, neuroplasticity, Autism and neuronal differentiation. Group: Biochemicals. Grades: Highly Purified. CAS No. 215923-54-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| CXCR2 Antagonist, Cpd 19 (CXCR2 Inhibitor, 3-(2-(cyclopentylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide) | A cell-permeable, cyclobutenedione derivative that acts as a potent antagonist of chemokine receptor CXCR2 (IL8RB) (IC50 = 8nM). Reported to inhibit CXCR2-mediated chemotaxis in a CXCR2 expressing cell line (IC50 = 145nM). Exhibits good stability in human and rat liver microsomal preparations (>50% remaining after 30 min at 37°C). Group: Biochemicals. Grades: Highly Purified. CAS No. 473728-67-5. Pack Sizes: 2mg. US Biological Life Sciences. | Worldwide |
| CXCR3 Antagonist (GPR9 Antagonist, 4-cyano-N- (3-fluoro-4- (1H-tetrazol-5-yl) benzyl) -N- (2-fluorobenzyl) benzenesulfonamide, AS612568, CD183 Antagonist) | An arylsulfonamide derivative that acts as a CXCR3 antagonist (IC50 = 192nM against CXCL10-induced chemotaxis of hCXCR3-overexpressing L1.2 cells) with good aqueous solubility (>100uM at pH 7.4). Shown to be orally available in mice (83% bioavailability; t1/2 = 1h; 10mg/kg p.o.) in vivo and display a medium intrinsic clearance (CIint = 17uL/min/mg) in in vitro mouse liver microsome stability test. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C??H??F?N6O?S. US Biological Life Sciences. | Worldwide |
| CXCR4 Antagonist III (Fusin Antagonist III, N2- (4- ( (3- (Cyclohexylamino) propylamino) methyl) benzyl) -N4- (piperidin-4-yl) quinazoline-2,4-diamine, 2HCl) | A cell-permeable quinazoline compound that acts as a potent and reversible CXCR4 antagonist (IC50=36.2nM for SDF-1/CXCL12 binding to hCXCR4-transfected HEK293 membrane) with selectivity over closely related human chemokine receptors CXCR2, CCR2, CCR4 and CCR5 (IC50 >10uM). Shown to inhibit CXCL12-induced Ca2+-mobilization and cell migration in hCXCR4-HEK293 cells (IC50=100.1 and 41nM, respectively), and rapidly mobilize CXCR4+, CD34+ and CD133+ stem cells from bone marrow in C57BL/6 male mice (6mg/kg, s.c). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| CXCR4 Antagonist IV, TF14016 (Fusin Antagonist IV) | A 14-aa internally disulfide-bonded peptide that potently competes against SDF-1alpha/CXCL12 for CXCR4 binding (IC50 = 0.91nM; [SDF-1] = 100nM) and protects MT-4 cells against X4-HIV strain HIV-1IIIB infection (EC50 = 4nM in 5 d; MOI = 0.01) with no significant cytotoxicity (CC50 = 56uM; 5 d). Inhibits SDF-1-induced Ca2+ mobilization (IC50 = 4.5nM; [SDF-1] = 30nM; CXCR4-expressing CHO cells) in vitro and effectively prevents CXCR4-dependent 5BC-5 metastasis in NK-depleted SCID mice in vivo (10mg/kg i.p.) in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2mg. Molecular Formula: C???H???FN??O??S?. xH?O, Sequence: N alpha-4-fluorobenzoyl-Arg-Arg-Nal-Cys4-Tyr-Cit-Lys-D-Lys-Pro-Tyr-Arg-Cit-Cys¹3-Arg-NH2 (Disulfide bond: 4 ? 13; Nal = L-3-(2-naphthyl)alanine; Cit = L-citrulline). US Biological Life Sciences. | Worldwide |
| Cyanocobalamin-b-carboxylic Acid | Cyancobalamin-b-carboxylic Acid is a Vitamin B12 (V676005) derivative, which is a water-soluble vitamin with a key role in the normal functioning of the brain and nervous system, and for the formation of blood. Group: Biochemicals. Grades: Highly Purified. CAS No. 38218-77-8. Pack Sizes: 250ug, 1mg. Molecular Formula: C63H87CoN13O15P. US Biological Life Sciences. | Worldwide |
| Cyclo [3-? (2-? naphthalenyl) ? -? L-? alanylglycyl-? D-? tyrosyl-? L-? arginyl-? L-? arginyl] | Cyclo [3-? (2-? naphthalenyl) ? -? L-? alanylglycyl-? D-? tyrosyl-? L-? arginyl-? L-? arginyl] is a CXCR4 antagonist with anti-HIV properties. Group: Biochemicals. Grades: Highly Purified. CAS No. 606968-52-9. Pack Sizes: 1mg, 5mg. Molecular Formula: C36H47N11O6, Molecular Weight: 729.83. US Biological Life Sciences. | Worldwide |
| Cyclopamine-KAAD (3-Keto-N-aminoethyl-aminocaproyldi hydrocinnamoyl cyclopamine, Shh Signaling Antagonist II) | A potent, cell-permeable analog of Cyclopamine that specifically inhibits the Hedgehog (Hh) signaling with similar or lower toxicity (IC50 = 20nM in Shh-LIGHT2 assay; 50nM in p2Ptch-/-cells; 500nM in SmoA1-LIGHT cells). Binds to SmoA1 and promotes its exit from the endoplasmic reticulum. Suppresses both the ShhNp-induced pathway activity and SmoA1-induced reporter activity. Shown to sensitize human glioma cells to TRAIL-induced apoptosis. Group: Biochemicals. Grades: Purified. CAS No. 306387-90-6. Pack Sizes: 100ug. Molecular Formula: C??H??N?O?, Primary Target: Hh signaling in Shh-light2 assay. US Biological Life Sciences. | Worldwide |
| Cyclopenol | Antimicrobial. Phytotoxic. Group: Biochemicals. Grades: Highly Purified. CAS No. 20007-85-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Cyclotetrakis(1,4-butylene Terephthalate) | Cyclotetrakis(1,4-butylene terephthalate) is a cyclic trimer of poly(butylene terephthalate), a thermoplastic engineering polymer. Group: Biochemicals. Alternative Names: 3, 8, 15, 20, 27, 32, 39, 44-Octaoxapentacyclo[44. 2. 2. 210, 13. 222, 25. 234, 37]hexapentaconta-10, 11, 12, 22, 23, 24, 34, 35, 36, 46, 48, 49-dodecaene-2, 9, 14, 21, 26, 33, 38, 45-octone; 3, 8, 15, 20, 27, 32, 39, 44-Octaoxapentacyclo[44. 2. 2. 210, 13. 222, 25. 234, 37]hexapentaconta-10, 12, 22, 24, 34, 36, 46, 48, 49, 51, 53, 55-dodecaene-2, 9, 14, 21, 26, 33, 38, 45-octone; Terephthalic acid, tetramol. cyclic tetramethylene ester; 1,4-Butanediol, tetramol. cyclic terephthalate. Grades: Highly Purified. CAS No. 29278-72-6. Pack Sizes: 1mg. Molecular Formula: C??H??O??, Molecular Weight: 880.89. US Biological Life Sciences. | Worldwide |
| Cypermethrin (Phenoxy-d5) Isomeric Mixture | Cypermethrin (Phenoxy-d5) Isomeric Mixture is the deuterated version of Cypermethrin (C989000), which is synthetic pyrethroid insecticide that usully exists as a mixture of isomers. Ectoparasiticide. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C22H14D5Cl2NO3, Molecular Weight: 421.33. US Biological Life Sciences. | Worldwide |
| Cyt387 (CYT11387) | Cyt387 is an ATP-competitive inhibitor of JAK1 and JAK2 with IC50 values of 11nM and 18nM, respectively. Inhibits JAK3 at much higher concentrations (IC50 = 155nM). Group: Biochemicals. Alternative Names: N- (cyanomethyl) -4- (2- (4-morpholinophenylamino) pyrimidin-4-l) -benzamide. Grades: Highly Purified. CAS No. 1056634-68-4. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| (-)-Cytisine | A potent agonist selective for neuronal nAChRs (Ki = 2, 5890, 480, 329, and 492nM at alpha4beta2, alpha7, alpha3beta4, alpha6/alpha4beta4, alpha1beta1upsilon-delta, respectively). Clinically used as a smoking cessation medicine and often used in addiction studies.CAS No.485-35-8. Group: Biochemicals. Alternative Names: nAChR Agonist, (-)-Cytisine, Nicotinic Acetylcholine Receptor Agonist, (-)-Cytisine, Baptitoxine, Sophorine. Grades: Highly Purified. CAS No. 485-35-8. Pack Sizes: 10mg. Molecular Formula: C??H??N?O. US Biological Life Sciences. | Worldwide |
| Cytoplasmic Dynein Inhibitor, Ciliobrevin D (2- (7-chloro-4-oxo-3, 4-dihydroquinazolin-2 (1H)-ylidene)-3- (2, 4-dichlorophenyl)-3-oxopropanenitrile) (AAA+ ATPase Motor Cytoplasmic Dynein Inhibitor) | A cell-permeable benzoyl dihydroquinazolinone derivative that acts as a reversible and specific blocker of AAA+ ATPase motor cytoplasmic dynein and disrupts spindle pole focusing, cold-stable microtubule formation, kinetochore-microtubule attachment, and melanosome aggregation in a dose-dependent manner (~10-40uM). Shown to perturb protein trafficking within the primary cilia and cause a significant increase in intraflagellar transport protein 88 (IFT88) levels at the distal tip of primary cilia. Reported to disrupt primary cilium-dependent Gli regulation and block Hedgehog signaling. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Cytosine 99+% (HPLC) | Cytosine (C) is one of the four main bases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA). It is a pyrimidine derivative, with a heterocyclic aromatic ring and two substituents attached (an amine group at position 4 and a keto group at position 2). The nucleoside of cytosine is cytidine. In Watson-Crick base pairing, it forms three hydrogen bonds with guanine. Group: Biochemicals. Alternative Names: 4-Amino-2-hydroxypyrimidine; 4-Amino-2-oxo-1,2-dihydropyrimidine. Grades: Highly Purified. CAS No. 71-30-7. Pack Sizes: 25g, 100g, 250g. US Biological Life Sciences. | Worldwide |
| Cytostatin (5,6-Dihydro-6-(6-hydroxy-1,5-dimethyl-4-(phosphonooxy)-7,9,11-tridecatrienyl)-5-methyl-2H-pyran-2-one) | Potent and selective protein phosphatase 2A (PP2A) inhibitor. Cell adhesion inhibitor. Inhibits the adhesion of B16 melanoma cells to laminin and collagen type IV in a dose dependent manner but not to fibronectin. Antitumor agent. Antimetastatic. Apoptosis inducer. Group: Biochemicals. Grades: Purified. CAS No. 156856-30-3. Pack Sizes: 250ug. US Biological Life Sciences. | Worldwide |
| d-1, 3, 5(10), 6, 8-ESTRAPENTAEN-3, 17α-DIOL 3-SULPHATE SODIUM SALT | d-1, 3, 5(10), 6, 8-ESTRAPENTAEN-3, 17α-DIOL 3-SULPHATE SODIUM SALT. Group: Biochemicals. Alternative Names: 17α-DIHYDROEQUILENIN SULPHATE. CAS No. 56086-66-9. US Biological Life Sciences. | Worldwide |
| Dafadine-A ( (5- ( (2, 6-Dimethylphenoxy) methyl) isoxazol-3-yl) (4- (pyridin-4-yl) piperidin-1-yl) methanone, 4- (1- ( (5- ( (2, 6-Dimethylphenoxy) methyl) -3-isoxazolyl) carbonyl) -4-piperidinyl) pyridine, DAF-9 Cytochrome P450 Inhibitor, Dafadine-A) | A cell-permeable isoxazoloamide compound that specifically inhibits DAF-9 activity in C. elegans (~20uM) without affecting the activity of DAF-12 and sterol- and oxysterol-metabolizing P450s. Reversibly targets the catalytic heme iron of DAF-9 cytochrome p450 and induce a constitutive dauer (Daf-c), distal-tip cell migration (Mig) and protruding vulval (Pvl) phenotypes in wild-type C. elegans (at ~25uM). Also, shown to be one of the most potent inhibitors of CYP27A1, the mammalian ortholog of DAF-9. Robustly promotes dauer formation (non-aging stress-resistant alternative third larval stage) only in wild type C. elegans and extends their life span by about 29%. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. Molecular Formula: C??H??N?O?. US Biological Life Sciences. | Worldwide |
| D-Amino Acid Oxidase Inhibitor III, AS057278 (5-methyl-1H-pyrazole-3-carboxylic Acid, DAAO Inhibitor III) | A cell-permeable pyrazolocarboxylic acid that acts as a selective D-amino acid oxidase (DAO/DAAO/DAMOX/OXDA) inhibitor (IC50 = 910nM against human DAO; [D-ser] = 10mM) and effectively protects DAO overexpressing cultures from oxidative stress-induced cell death upon D-Ser (50mM) exposure (ED50 ≤3.95uM), while exhibiting little affinity toward nMDAR glycine binding site or inhibitory activity against D-aspartate oxidase (DDO/DSOX). Reported to be orally available and blood-brain barrier-permeant in rats and effectively prevent PCP (phencyclidine) from suppressing PPI (prepulse inhibition) response in mice (single 80mg/kg or 56X 20mg/kg/12h b.i.d. oral dosages) in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 402-61-9. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| Daptomycin Impurity B1-I | Daptomycin Impurity B1-1 is an impurity of Daptomycin (D193350), cyclic lipopeptide antibiotic derived from a fermentation product of Streptomyces roseosporus; disrupts plasma membrane function in gram-positive bacteria. Antibacterial. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C44H66N10O15; (C2HF3O2). US Biological Life Sciences. | Worldwide |
| D-Asparagine | D-Asparagine is an isomer of L-Asparagine (A790005) and is used by bacteria (such as Saccharomyces cerevisiae) as a sole nitrogen source for replication. L-Asparagine is also a competitive inhibitor of staphylococcal L-asparaginase and is used as a reagent to synthesize peptide antibiotics. Group: Biochemicals. Grades: Highly Purified. CAS No. 2058-58-4. Pack Sizes: 10g, 25g. Molecular Formula: C4H8N2O3, Molecular Weight: 132.12. US Biological Life Sciences. | Worldwide |
| DBZ (N-[(1S)-2-[[(7S)-6,7-Dihydro-5-meth yl-6-oxo-5H-dibenz[b,d]azepin-7-yl]amino]-1-methyl -2-oxoethyl] -3, 5-difluoro Benzene acetamide) | DBZ (N-[(1S)-2-[[(7S)-6,7-Dihydro-5-meth yl-6-oxo-5H-dibenz[b,d]azepin-7-yl]amino]-1-methyl -2-oxoethyl] -3, 5-difluoro Benzene acetamide) . Group: Biochemicals. Grades: Highly Purified. CAS No. 209984-56-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Decarestrictine D (Tuckolide, (4S,5S,8S,10R,E)-4,5,8-Trihydroxy-10-methyl-3,4,5,8,9,10-hexahydro-2H-oxecin-2-one) | Hypolipidemic and cholesterol biosynthesis inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 127393-89-9. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Decatone | Decatone is used in the synthesis of 6-Isopropyl-2-decahydronaphthalenol, which is a fragrance raw material, used in the perfumery industry. Group: Biochemicals. Grades: Highly Purified. CAS No. 34131-98-1. Pack Sizes: 10mg, 50mg. Molecular Formula: C13H22O, Molecular Weight: 194.31. US Biological Life Sciences. | Worldwide |
| Decoyinine (Angustmycin A, U-7984, 9-(6-Deoxy-D-beta-erythro-hex-5-en-2-ulofuranosyl)-adenine) | Nucleoside antibiotic. Antitumor compound. Xanthosine monophosphate (XMP) aminase inhibitor. RNA synthesis inhibitor. Specific GMP synthase inhibitor. Reduces intracellular GTP levels. Group: Biochemicals. Grades: Highly Purified. CAS No. 2004-4-8. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Decylubiquinone (2,3-Dimethoxy-5-methyl-6-decyl-1,4-benzoquinone) | A synthetic substrate of cytochrome and mitochondrial permeability transition pore (MPTP) inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 55486-00-5. Pack Sizes: 1mg, 10mg. US Biological Life Sciences. | Worldwide |
| Dehydroxytramadol Hydrochloride | Dehydroxytramadol Hydrochloride is an impurity of Tramadol Hydrochloride (T712500), an analgesic. Group: Biochemicals. Grades: Highly Purified. CAS No. 66170-32-9. Pack Sizes: 10mg, 100mg. Molecular Formula: C16H23NO; (HCl), Molecular Weight: 245.363645999999. US Biological Life Sciences. | Worldwide |
| δ-1,2,3,4,5,6-Hexachlorocyclohexane | δ-1,2,3,4,5,6-Hexachlorocyclohexane. Group: Biochemicals. Alternative Names: (1α, 2α, 3α, 4 β,5α,6 β)-1,2,3,4,5,6-Hexachlorocyclohexane; Delta-BHC; δ-1,2,3,4,5,6-Hexachlorocyclohexane; δ-666; δ-BHC; δ-Benzene hexachloride; δ-HCH; δ-Hexachlorocyclohexane; δ-Lindane. Grades: Highly Purified. CAS No. 319-86-8. Pack Sizes: 100mg. Molecular Formula: C6H6Cl6, Molecular Weight: 290.83. US Biological Life Sciences. | Worldwide |
| Δ1-Androstenedione | Δ1-Androstenedione as a prodrug of Δ1-Testosterone. Group: Biochemicals. Grades: Highly Purified. CAS No. 571-40-4. Pack Sizes: 10mg, 100mg. Molecular Formula: C19H26O2. US Biological Life Sciences. | Worldwide |
| Δ2-Cefditoren Pivoxil | Δ2-Cefditoren Pivoxil. Group: Biochemicals. Alternative Names: (6R, 7R) -7-[[ (2Z) - (2-Amino-4-thiazolyl) (methoxyimino) acetyl]amino]-3-[ (1Z) -2- (4-methyl-5-thiazolyl) ethenyl]-8-oxo-5-thia-1-azabicyclo[4. 2. 0]oct-3-ene-2-carboxylic Acid (2,2-Dimethyl-1-oxopropoxy)methyl Ester. Grades: Highly Purified. CAS No. 148774-47-4. Pack Sizes: 5mg. Molecular Formula: C25H28N6O7S3, Molecular Weight: 620.72. US Biological Life Sciences. | Worldwide |
| Δ2-Cefuroxime Methyl Ester | Δ2-Cefuroxime Methyl Ester is a potentially related compound in cephalosporin antibacterial compounds. Group: Biochemicals. Alternative Names: (6R, 7R) -3-[[ (Aminocarbonyl) oxy]methyl]-7-[[ (2Z) -2- (2-furanyl) -2- (methoxyimino) acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4. 2. 0]oct-3-ene-2-carboxylic Acid Methyl Ester. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Δ4-Cholesten-3-one | Δ4-Cholesten-3-one. Group: Biochemicals. Alternative Names: (+)-4-Cholesten-3-one; (17 β)-17-Octylandrost-4-en-3-one; 3-Oxocholest-4-ene; Δ4-Cholestenone; 4-Cholesten-3-one; 4-Cholestenone; Cholesterone; NSC 134926; NSC 63000. Grades: Highly Purified. CAS No. 601-57-0. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Δ4-Pregnene-3,20-diol | Intermediate in the preparation of Pregnenolone and its derivatives. Group: Biochemicals. Alternative Names: 3-Hydroxy-4-pregnen-20-ol; 3,20-Dihydroxypregn-4-ene. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Δ5(10),6,8(9)-D-(-)-Norgestrel | Δ5(10),6,8(9)-D-(-)-Norgestrel. Group: Biochemicals. Alternative Names: Levonorgestrel Impurity W. Grades: Highly Purified. CAS No. 155683-59-3. Pack Sizes: 5mg. Molecular Formula: C22H26O, Molecular Weight: 306.44. US Biological Life Sciences. | Worldwide |
| δ-Carboline | δ-Carboline. Group: Biochemicals. Alternative Names: 5H-Pyrido[3,2-b]indole. Grades: Highly Purified. CAS No. 245-08-9. Pack Sizes: 50mg. Molecular Formula: C11H8N2, Molecular Weight: 168.19. US Biological Life Sciences. | Worldwide |
| δ-Valerolactone-d4 | δ-Valerolactone-d4. Group: Biochemicals. Alternative Names: 1-Oxacyclohexan-2-one-d4; 2-Oxotetrahydropyran-d4; 5-Hydroxypentanoic Acid Lactone-d4; 5-Hydroxypentanoic acid δ-lactone-d4; 5-Valerolactone-d4; NSC 6247-d4; Pentan-5-olide-d4; 5-Hydroxypentanoic Acid δ-Lactone-d4; Tetrahydro-2-pyranone-d4; Tetrahydro-2H-pyran-2-one-d4; δ-Valeryllactone-d4. Grades: Highly Purified. CAS No. 42932-61-6. Pack Sizes: 10mg. Molecular Formula: C5H4D4O2, Molecular Weight: 104.14. US Biological Life Sciences. | Worldwide |
| Deoxycholic Acid-d5 3-O-Sulfate Disodium Salt | Deoxycholic Acid-d5 3-O-Sulfate Disodium Salt is a labelled impurity of Cholic Acid (C432600), it is produced and isolated from liver cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C24H33D5Na2O7S, Molecular Weight: 521.63. US Biological Life Sciences. | Worldwide |
| Deoxymanumycin A | Derivative of the farnesyltransferase inhibitor Manumycin A. This compound has not yet been thoroughly tested for its biological activity. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Depudecin (4,5:8,9-Dianhydro-1,2,6,7,11-pentadeoxy-D-threo-D-ido-undeca-1,6-dienitol) | A fungal metabolite that acts as a potent HDAC inhibitor (IC50 = 4.7uM for HDAC1). It reverts ras- and src-transformed NIH3T3 cells to a flat phenotype (1ug/ml). Group: Biochemicals. Grades: Highly Purified. CAS No. 139508-73-9. Pack Sizes: 100ug. US Biological Life Sciences. | Worldwide |
| Descyano-[(E)-methyl 3-methoxyacrylate] Azoxystrobin | Descyano-[(E)-methyl 3-methoxyacrylate] Azoxystrobin is an impurity of the drug Azoxystrobin (A965150). Azoxystrobin (A965150) is a strobilurin fungicide. It inhibits mitochondrial respiration by blocking electron transfer between cytochromes b and c1; agricultural fungicide. Group: Biochemicals. Grades: Highly Purified. CAS No. 131860-85-0. Pack Sizes: 5mg, 10mg. Molecular Formula: C26H24N2O8, Molecular Weight: 492.48. US Biological Life Sciences. | Worldwide |
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