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| Product | Description | |
|---|---|---|
| 8-AET-c-diAMP-Agarose | 8-AET-c-diAMP-Agarose is the bacterial second messenger c-diAMP immobilized on agarose by an aminoethylthio spacer, which possibly can be used in affinity chromatography of c-diAMP-responsive proteins. Synonyms: 8- (2- Aminoethylthio)- cyclic diadenosine monophosphate, immobilized on agarose gel. |  |
| 8-AET-c-diGMP | 8-AET-c-diGMP is an analogue of c-diGMP, the bacterial second messenger, which can be used as a ligand for affinity chromatography or for coupling of labelling structures such as fluorophores. Synonyms: 8- (2- Aminoethylthio)- cyclic diguanosine monophosphate, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C22H29N11O14P2S (free acid). Mole weight: 765.6 (free acid). | |
| 8-AET-c-diGMP-Agarose | 8-AET-c-diGMP-Agarose is the bacterial second messenger c-diGMP immobilized on agarose by an aminoethylthio spacer, which possibly can be used in affinity chromatography of c-diGMP-responsive proteins. Synonyms: 8- (2- Aminoethylthio)- cyclic diguanosine monophosphate, immobilized on agarose gel. | |
| 8-AET-cGMP | 8-AET-cGMP is a ligand in affinity chromatography and can be modified with fluorophores or other markers. Synonyms: 8- (2- Aminoethylthio)guanosine- 3', 5'- monophosphate. Grades: ≥ 98% by HPLC. CAS No. 115974-70-4. Molecular formula: C12H17N6O7PS. Mole weight: 420.4. | |
| 8-AET-cGMP-Agarose | 8-AET-cGMP-Agarose is the second messenger cGMP immobilized on agarose by an aminoethylthio spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. Synonyms: 8- (2- Aminoethylthio)guanosine- 3', 5'- cyclic monophosphate; immobilized on agarose gel. | |
| 8-AET-GTP | 8-AET-GTP is a ligand in affinity chromatography and can be modified with fluorophores and other markers. Synonyms: 8-(2-Aminoethylthio)guanosine-5'-O-triphosphate, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C12H21N6O14P3S (free acid). Mole weight: 598.3 (free acid). | |
| 8-AHA-2-Cl-cAMP | 8-AHA-2-Cl-cAMP is a selective cAMP analogue that has a preference for side B I of PKA. Synonyms: 8- (6- Aminohexylamino)- 2- chloroadenosine- 3', 5'- cyclic monophosphate. Grades: ≥ 98% by HPLC. Molecular formula: C16H25ClN7O6P. Mole weight: 477.8. | |
| 8-AHA-2'-O-Me-cAMP | 8-AHA-2'-O-Me-cAMP is a ligand in affinity chromatography of cAMP binding proteins that do not require an intact 2'-OH group, such as the exchange protein activated by cAMP (Epac) and certain phosphodiesterases. Synonyms: 8- (6- Aminohexyl)amino- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate. Grades: ≥ 98% by HPLC. Molecular formula: C17H28N7O6P. Mole weight: 457.4. | |
| 8-AHA-2'-O-Me-cAMP-Agarose | 8-AHA-2'-O-Me-cAMP-Agarose is the second messenger cAMP with a methylated ribose 2'-hydroxy group immobilized on agarose by an aminohexylamino spacer, which can be used in affinity chromatography of cAMP-responsive proteins such as the exchange protein activated by cyclic AMP (Epac) and certain phosphodiesterases. Synonyms: 8- (6- Aminohexylamino)- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate; immobilized on agarose gel. | |
| 8-AHA-cAMP | 8-AHA-cAMP is a selective cAMP analogue preferring site B of R I of cAMP-dependent protein kinase. It can be active to site A of R I and site B of R II combining with 8-PIP-cAMP. Synonyms: 8- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphate. Grades: ≥ 98% by HPLC. CAS No. 39824-30-1. Molecular formula: C16H26N7O6P. Mole weight: 443.4. | |
| 8-AHA-cAMP-Agarose | 8-AHA-cAMP-Agarose is the second messenger cAMP immobilized on agarose by an aminohexylamino spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. Synonyms: 8- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphate; immobilized on agarose gel. | |
| 8-AHT-GTP | 8-AHT-GTP is a ligand in affinity chromatography and can be modified with fluorophores and other markers. Synonyms: 8-(6-Aminohexylthio)guanosine-5'-O-triphosphate, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H29N6O14P3S (free acid). Mole weight: 654.4 (free acid). | |
| 8-Allyloxy-2'-deoxyguanosine | 8-Allyloxy-2'-deoxyguanosine, a remarkable biomedicine, exhibits immense potential for therapeutic applications in diverse medical conditions. Meticulous investigations have shed light on its profound impact in combatting cancer, viral infections, and genetic disorders, rendering it a focal point of research. By delicately manipulating intricate cellular pathways and precisely targeting molecular processes, this compound showcases its capabilities as a formidable treatment strategy. Grades: ≥ 90%. CAS No. 869354-71-2. Molecular formula: C13H17N5O5. Mole weight: 323.20. | |
| 8-(Allyloxy)guanosine | A guanosine derivative as an immunostimulant. Synonyms: 8-Allyloxyguanosine; 8-(2-Propenyloxy)guanosine; Guanosine, 8-(2-propen-1-yloxy)-; 8-(Allyloxy)-2-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one. Grades: ≥95%. CAS No. 126138-81-6. Molecular formula: C13H17N5O6. Mole weight: 339.30. | |
| 8-Allyloxy-N2-isobutyryl-2'-deoxyguanosine | 8-Allyloxy-N2-isobutyryl-2'-deoxyguanosine is a novel compound with potential biomedical applications. It exhibiting antiviral properties and may be used in the development of drugs to research viral infections, such as herpes simplex virus. Synonyms: N-[9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-oxo-8-prop-2-enoxy-1H-purin-2-yl]-2-methylpropanamide. Grades: ≥ 90%. CAS No. 869354-75-6. Molecular formula: C17H23N5O6. Mole weight: 393.40. | |
| 8-Allylthioguanosine | 8-Allylthioguanosine is an exceptional compound, showcasing its remarkable efficacy in research of a wide array of viral infections. It exerts its inhibitory prowess by perturbing the intricate process of viral nucleic acid enhancement, thereby impeding the replication and dissemination of notorious viruses such as herpes simplex virus and human immunodeficiency virus (HIV). Synonyms: 8-(2-propenylthio)guanosine; 8-(2-propenylmercapto)guanosine; 8-Allylsulfanyl-2-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1,9-dihydro-purin-6-one; 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-prop-2-enylsulfanyl-1H-purin-6-one; 8-(Allylsulfanyl)guanosine; Guanosine, 8-(2-propen-1-ylthio)-. Grades: ≥95%. CAS No. 126092-30-6. Molecular formula: C13H17N5O5S. Mole weight: 355.37. | |
| 8-Amino-2'-deoxyadenosine | 8-Amino-2'-deoxyadenine is an antineoplastic compound manifesting proficiency in hampering the enhancement of DNA and RNA. Synonyms: 6,8-Diamino-9-(2-deoxy-β-D-erythro-pentofuranosyl)-9H-purine; NSC 101167; (2R,3S,5R)-5-(6,8-diamino-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol. Grades: ≥95%. CAS No. 13389-09-8. Molecular formula: C10H14N6O3. Mole weight: 266.26. | |
| 8-Amino-2'-deoxy-N6,N8-di-DMF-5'-O-DMT-adenosine 3'-CE phosphoramidite | 8-Amino-2'-deoxy-N6,N8-di-DMF-5'-O-DMT-adenosine 3'-CE phosphoramidite is a vital component used in the research and development of oligonucleotides for drug discovery. It offers efficient coupling to ensure accurate incorporation of adenosine nucleotides during the solid-phase research and development process. Synonyms: 5'-Dimethoxytrityl-N6,N8-bis(dimethylaminomethylidine)-8-amino-2'-deoxyAdenosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 8-Amino-dA-CE Phosphoramidite; 8-Amino-2'-deoxy-D-adenosine 3'-CE phosphoramidite. CAS No. 211676-21-0. Molecular formula: C46H59N10O6P. Mole weight: 879.01. | |
| 8-Amino Adenosine | The purine nucleoside analog; has role in induction of apoptosis in multiple myeloma. Uses: The purine nucleoside analog. Synonyms: 8-Aminoadenosine; 6,8-Diamino-9-β-D-ribofuranosyl-9H-purine; NSC 90394; (2R,3R,4S,5R)-2-(6,8-diamino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 8-Amino-D-adenosine. Grades: ≥95%. CAS No. 3868-33-5. Molecular formula: C10H14N6O4. Mole weight: 282.26. | |
| 8-Aminoadenosine-5'-triphosphate lithium salt | 8-Aminoadenosine-5'-triphosphate lithium salt is a pivotal biochemical compound characteristically employed in cellular research to investigate the mechanisms elucidating the varied roles of ATP, encompassing signal transduction and energy transfer. Its diverse derivatives, owing to their ability to modulate the activity of an array of ion channels and transporters, display a promising potential in battling afflictions like hypertension, arrhythmia, as well as cancer. Synonyms: 8-Amino-ATP. Molecular formula: C10H17N6O13P3·xLi. Mole weight: 522.20 (free acid). | |
| 8-Aminoguanosine | A potent inhibitor of purine nucleoside phosphorylase. Uses: A potent inhibitor of purine nucleoside phosphorylase. Synonyms: 2,8-Diaminoinosine; NSC 90390. Grades: 98%. CAS No. 3868-32-4. Molecular formula: C10H14N6O5. Mole weight: 298.26. | |
| 8-APT-cGMP | 8-APT-cGMP is an isozyme-selective stimulator of cGMP-dependent protein kinase I a with a prenference for type I a over I by a factor of 200. Synonyms: 8- (2- Aminophenylthio)guanosine- 3', 5'- monophosphate, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 144509-87-5. Molecular formula: C16H16N6O7PS · Na. Mole weight: 490.4. | |
| 8-Aza-2'-beta-C-methylguanosine | 8-Aza-2'-beta-C-methylguanosine: One compound, with a rather intricate name - 8-Aza-2'-beta-C-methylguanosine, finds significant application in the biomedical sector for research and development. In fact, scientists readily exploit its synthetic forerunner role while manufacturing a range of antiviral medications targeting RNA viruses, an area of paramount importance. Its unmatched constitution and characteristics render it an indispensable asset in the realm of drug exploration and medicinal chemistry, fostering the battle against debilitating viral afflictions. Grades: ≥95%. Molecular formula: C10H14N6O5. Mole weight: 298.26. | |
| 8-Aza-5'-AMP | 8-Aza-5'-AMP, a nucleoside analog, has been widely employed in exploring the activity of purine nucleoside phosphorylase (PNP) and its role in immune system functionality. Moreover, it maintains immense potential for conducting experiments on T-cell depletion and treating severe ailments like autoimmune diseases and cancer. Synonyms: 8- Azaadenosine- 5'- O- monophosphate. Molecular formula: C9H13N6O7P (free acid). Mole weight: 348.2 (free acid). | |
| 8-Aza-7-deaza-2'-deoxy-N2-DMF-5'-O-DMT-guanosine 3'-CE phosphoramidite | 8-Aza-7-deaza-2'-deoxy-N2-DMF-5'-O-DMT-guanosine 3'-CE phosphoramidite is a remarkably efficient phosphoramidite building block employed in solid-phase research and development, facilitating the generation of modified RNA or DNA oligonucleotides. Through its incorporation, 8-aza-7-deaza modifications are introduced. Synonyms: 5'-Dimethoxytrityl-N-dimethylformamidine-8-aza-7-deaza-2'-deoxyGuanosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 7-Deaza-8-aza-dG-CE Phosphoramidite (PPG). Grades: 95%. CAS No. 500891-26-9. Molecular formula: C43H53N8O7P. Mole weight: 824.91. | |
| 8-Aza-ATP | 8-Aza-ATP, a powerful and discriminating activator of the P2Y1 receptor, plays a critical role in an array of physiological processes, including platelet aggregation and neuroprotection. Its therapeutic uses have been explored in a litany of conditions, ranging from stroke and traumatic brain injury to glaucoma, and even hold promise for treating cancer via its potent antiproliferative and antitumor qualities. Synonyms: 8-Azaadenosine-5'-Triphosphate. Grades: ≥90% by AX-HPLC. Molecular formula: C9H15N6O13P3. Mole weight: 508.1. | |
| 8-Azaguanosine | It is a substrate of purine nucleoside phosphorylase (PNP)?. Synonyms: Azaguanosine; NSC 46788; NSC 130283; 7H-1,2,3-Triazolo(4,5-d)pyrimidin-7-one, 5-amino-3,4-dihydro-3-beta-D-ribofuranosyl-; 5-Amino-3,6-dihydro-3-β-D-ribofuranosyl-7H-1,2,3-triazolo[4,5-d]pyrimidin-7-one. Grades: ≥95%. CAS No. 2133-80-4. Molecular formula: C9H12N6O5. Mole weight: 284.23. | |
| 8-Azido-2'-deoxyadenosine | 8-Azido-2'-deoxyadenosine is a potent nucleoside analogue extensively for its ability to selectively inhibit DNA enhancement. This versatile compound finding application in the research of various diseases, including cancers and viral infections. Synonyms: (2R,3S,5R)-5-(6-amino-8-azido-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol; Adenosine, 8-azido-2'-deoxy-. Grades: ≥95%. CAS No. 131265-35-5. Molecular formula: C10H12N8O3. Mole weight: 292.17. | |
| 8-Azido-adenosine | 8-Azido-adenosine, a highly versatile compound employed extensively in the realm of biomedical research, serves as an invaluable vehicle for investigating intricate nucleotide metabolism and underlying biological processes. Renowned for its prowess as a tool compound, it ensures precise nucleoside labeling, facilitates comprehensive enzymatic studies, and facilitates the unmasking of intricate protein-protein interactions. The azido functional group it harbors empowers researchers to venture into the realm of bioorthogonal chemistry, enabling thorough exploration of diverse drug targets and mechanisms intricately tied to the realm of disease. Synonyms: 8-Azidoadenosine; (2R,3R,4S,5R)-2-(6-amino-8-azido-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 8-Azido Adenosine. Grades: ≥95% by HPLC. CAS No. 4372-67-2. Molecular formula: C10H12N8O4. Mole weight: 308.25. | |
| 8-Azidoadenosine-5'-Triphosphate | 8-Azidoadenosine-5'-Triphosphate is a crucial tool in compound for studying ATP-dependent processes. With its azido group, it enables selective photo-crosslinking to ATP-binding proteins and subsequent identification. Widely used in drug discovery and proteomics, it aids in investigating ATP-dependent diseases like cancer and neurodegenerative disorders. Uses: Affinity labels. Synonyms: 8-Azido-ATP. Grades: ≥90% by AX-HPLC. CAS No. 53696-59-6. Molecular formula: C10H15N8O13P3. Mole weight: 548.19. | |
| 8-Azido-ADP | 8-Azido-ADP is a renowned nucleotide analogue, profoundly disrupting a spectrum of enzymes engaged in DNA replication and repair. Synonyms: 8-Azido-adenosine-5'-diphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H14N8O10P2 (free acid). Mole weight: 468.21 (free acid). | |
| 8-Azido-AMP | 8-Azido-AMP is also known as 8-Azidoadenosine monophosphate, facilitating the meticulous examination of intricate protein functionality, intricate protein-protein associations is and intricate enzymatic behavior. Additionally, it profoundly contributes to the elucidation and understanding of complex drug-target relationships and the enlightenment of promising therapeutic candidates targeting a wide spectrum of ailments. Synonyms: 8-Azido-adenosine-5'-monophosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H13N8O7P (free acid). Mole weight: 388.23 (free acid). | |
| 8-Azido-ATP | 8-Azido-ATP is a synthetic form of ATP that contains an azide group. This molecule has been used extensively in chemical biology to study ATP-binding proteins and enzymes. By introducing an azide group into the ATP molecule, researchers can use click chemistry to attach probes or tags to specific sites in the ATP-binding pocket. This has been useful for identifying new drug targets and studying the mechanism of ATP-dependent processes. Synonyms: 8-Azido-adenosine-5'-triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 81380-25-8. Molecular formula: C10H15N8O13P3 (free acid). Mole weight: 548.19 (free acid). | |
| 8-Benzyloxy-2'-deoxyguanosine | 8-Benzyloxy-2'-deoxyguanosine is a synthetic compound inhibiting the replication of viruses, including Herpes Simplex Virus (HSV). This compound has shown potential in the research of viral infections by specifically targeting the replication process. Synonyms: 2'-Deoxy-8-(phenylmethoxy)guanosine; 8-(benzyloxy)deoxyguanosine; 8-Benzyloxy-2'-deoxy-D-guanosine. Grades: ≥95%. CAS No. 96964-90-8. Molecular formula: C17H19N5O5. Mole weight: 373.36. | |
| 8-Benzyloxy-3'-deoxy-3'-fluoroguanosine | 8-Benzyloxy-3'-deoxy-3'-fluoroguanosine, a highly significant compound utilized in the field of biomedicine, assumes a pivotal function in combating diverse viral infections and cancers. Its unique mechanism involves the inhibition of specific viruses, thereby showcasing potent antiviral characteristics. Moreover, its exceptional potential as an agent against cancer lies in its capacity to impede the growth and proliferation of malignant cells. Synonyms: 2-amino-9-[(2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-phenylmethoxy-1H-purin-6-one. Grades: ≥95%. CAS No. 2389988-61-6. Molecular formula: C17H18FN5O5. Mole weight: 391.35. | |
| 8-Benzyloxy-3'-deoxyguanosine | 8-Benzyloxy-3'-deoxyguanosine, an extensively studied biomedicine, stands as a beacon of hope in combating viral infections, especially within the realm of antiviral therapeutics. Notably, this remarkable compound unveils an impressive repertoire, showcasing its potent antiviral prowess against an array of DNA and RNA viruses. Lending credence to its potential for drug development, it boasts a mechanism of action centered around inhibiting viral replication. Synonyms: Guanosine, 3'-deoxy-8-(phenylmethoxy)-; 2-amino-9-[(2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-phenylmethoxy-1H-purin-6-one. Grades: ≥95%. CAS No. 2389988-57-0. Molecular formula: C17H19N5O5. Mole weight: 373.36. | |
| 8-Benzyloxy-9-(b-D-xylofuranosyl)guanine | 8-Benzyloxy-9-(b-D-xylofuranosyl)guanine, a formidable antiviral compound widely utilized in the biomedical sector, boasts a remarkable repertoire of vital functions. Its exceptional potency enables the efficacious extermination of herpes simplex virus (HSV) and varicella-zoster virus (VZV) infections, cementing its significance in combating viral afflictions. Unraveling its dynamic mechanism of action reveals an intricate disruption of viral DNA replication, debilitating the pernicious proliferation of these malevolent entities. Synonyms: 2-amino-9-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-phenylmethoxy-1H-purin-6-one. Grades: ≥95%. Molecular formula: C17H19N5O6. Mole weight: 389.36. | |
| 8-Benzyloxyadenosine | 8-Benzyloxyadenosine is a key compound in biomedicine used for its potential therapeutic benefits in treating various diseases. It acts as an adenosine receptor agonist, primarily targeting A1 and A3 receptors. This unique property makes it an essential tool in studying the role of adenosine receptors in conditions such as cardiovascular diseases, cancer, and neurodegenerative disorders. Synonyms: Adenosine, 8-(phenylmethoxy)-; (2R,3R,4S,5R)-2-(6-Amino-8-(benzyloxy)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. Grades: ≥95%. CAS No. 131265-29-7. Molecular formula: C17H19N5O5. Mole weight: 373.36. | |
| 8-(Benzyloxy)guanosine | 8-(Benzyloxy)guanosine is a vital bioactive compound exhibiting potential in studying various diseases, such as cancer. With its inhibition abilities, it targets specific cellular pathways. Synonyms: 8-(Phenylmethoxy)guanosine; NSC 90391; 8-Benzyloxyguanosine; 2-Amino-8-(benzyloxy)-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one. Grades: ≥95%. CAS No. 3868-36-8. Molecular formula: C17H19N5O6. Mole weight: 389.36. | |
| 8-Benzyloxy-N2-isobutyryl-2'-deoxyguanosine | 8-Benzyloxy-N2-isobutyryl-2'-deoxyguanosine is an antiviral compound, holding immense potential in the development of antiviral therapeutics. Synonyms: N-[9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-oxo-8-phenylmethoxy-1H-purin-2-yl]-2-methylpropanamide; 8-BENZYLOXY-N2-ISOBUTYRYL-2/'-DEOXYGUANOSINE;8-(Benzyloxy)-2'-deoxy-N-(2-methylpropanoyl)guanosine; N-(8-(benzyloxy)-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide. Grades: ≥ 90%. CAS No. 136859-75-1. Molecular formula: C21H25N5O6. Mole weight: 443.46. | |
| 8-Biotin-11-cAMP | 8-Biotin-11-cAMP is a biochemical compound used in biomedicine research to investigate cAMP-mediated cellular signaling pathways. It is commonly used in molecular pharmacology and drug discovery to characterize the effects and pharmacokinetics of various drugs related to cAMP. Additionally, 8-Biotin-11-cAMP is used as a tool to study and target certain diseases, such as cancer and metabolic disorders, where cAMP signaling plays a role in their pathophysiology. Grades: ≥ 98% by HPLC. Molecular formula: C28H41N9O9PS2 · Na. Mole weight: 765.8. | |
| 8-Biotin-11-c-diAMP | 8-Biotin-11-c-diAMP is an analogue of c-diAMP, the bacterial second messenger. It is a potential tracer in immunoassays and commonly used for affinity chromatography and pull-down assays. Grades: ≥ 95% by HPLC. Molecular formula: C38H54N14O15P2S2 (free acid). Mole weight: 1073 (free acid). | |
| 8-Biotin-11-c-diGMP | 8-Biotin-11-c-diGMP is an analogue of c-diGMP, the bacterial second messenger. It is a potential tracer in immunoassays and commonly used for affinity chromatography and pull-down assays. Grades: ≥ 95% by HPLC. Molecular formula: C38H54N14O17P2S2 (free acid). Mole weight: 1105 (free acid). | |
| 8-Biotin-11-cGMP | 8-Biotin-11-cGMP, a cyclic guanosine monophosphate (cGMP) analog, boasts extensive use within scientific research wherein protein kinases and physiological processes, including smooth muscle relaxation and platelet activation, are studied. Studies have also hinted at the prospect of employing 8-Biotin-11-cGMP in combating diseases characterized by hypertension and erectile dysfunction. Grades: ≥ 98% by HPLC. Molecular formula: C28H41N9O10PS2·Na. Mole weight: 781.8. | |
| 8-Br-2',3',6'-TAc-Guo | 8-Br-2',3',6'-TAc-Guo is a bioactive compound, used for studying bacterial and viral afflictions by impeding the proliferation of malignant cells. CAS No. 16717-46-0. Molecular formula: C16H18N6O8Br. Mole weight: 488.6. | |
| 8-Br-2'-O-Me-cAMP-AM | 8-Br-2'-O-Me-cAMP-AM is a precursor of 8-Br-2'-O-Me-cAMP, the specific Epac agonist. 8-Br-2'-O-Me-cAMP is released after the metabolism of 8-Br-2'-O-Me-cAMP-AM by esterases. Synonyms: 8- Bromo- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate, acetoxymethyl ester. Grades: ≥ 97% by HPLC for mixture of isomers. Molecular formula: C14H17BrN5O8P. Mole weight: 494.2. | |
| 8-Br-2'-O-Me-cGMP | 8-Br-2'-O-Me-cGMP is an analogue of cGMP that does not activate both protein kinase G and Epac. It is often used as an inactive control versus 8-Br-cGMP. Synonyms: 8- Bromo- 2'- O- methylguanosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. Molecular formula: C11H12BrN5O7P · Na. Mole weight: 460.1. | |
| 8-Br-cAMP | 8-Br-cAMP, a synthetic cyclic adenosine monophosphate (cAMP) analog, demonstrates versatile potential in medical and biological sciences. From inhibiting platelet aggregation and inducing cellular differentiation, to regulating gene expression and advancing therapeutic research - its applications span across cancer, cardiovascular, and endocrine disorders. Its potential for enhancing cellular signaling and invigorating treatment research sets it apart as a tool for shaping the future of life sciences. Uses: Reprogramming. Synonyms: 8-Br-cAMP; BCAMP; 8-Bromo-cyclic AMP; 8-Bromoadenosine 3',5'-cyclic monophosphate; 8-bromo-cAMP; 8-Bromo-cyclic 3',5'-AMP; 8-Bromoadenosine cyclic 3',5'-phosphate; Cyclic 8-bromoadenosine 3',5'-monophosphate; 8-BROMO CYCLIC ADENOSINE MONOPHOSPHATE; 8-Bromoadenosine 3',5'-monophosphate; 8-bromo-3',5'-cyclic AMP; Cyclic AMP, 8-bromo; 5QO1UW05Q5; CHEBI:64211; MFCD00075580; Adenosine, 8-bromo-, cyclic 3',5'-(hydrogen phosphate); 8-bromoadenosine 3',5'-(hydrogen phosphate); (4AR,6R,7R,7aS)-6-(6-amino-8-bromo-9H-purin-9-yl)-2,7-dihydroxytetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine 2-oxide1111. Grades: 0.98. CAS No. 23583-48-4. Molecular formula: C10H11BrN5O6P. Mole weight: 408.1. | |
| 8-Br-c-diGMP | 8-Br-c-diGMP is an analogue of c-diGMP, the bacterial second messenger, which can be used for binding studies and precursor for further modifications with spacers or labels. Synonyms: 8- Bromo- cyclic diguanosine monophosphate, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C20H23BrN10O14P2 (free acid). Mole weight: 769.3 (free acid). | |
| 8-Br-dA-CE Phosphoramidite | 8-Br-dA-CE Phosphoramidite is a valuable compound used in compound for the research and development of DNA and RNA oligonucleotides. It acting as a building block during the solid-phase research and development of modified DNA and RNA strands, enabling the incorporation of the 8-bromodeoxyadenosine (8-Br-dA) nucleoside. These modified nucleotides find applications in various research areas, including drug discovery, genetic engineering is and diagnostics. Synonyms: 5'-Dimethoxytrityl-N6-dimethylaminomethylidene-8-bromo-2'-deoxyAdenosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Grades: 95%. CAS No. 207906-54-5. Molecular formula: C43H52N8O6PBr. Mole weight: 887.81. | |
| 8-Bromo-2',3',5'-tri-O-acetyladenosine | 8-Bromo-2',3',5'-tri-O-acetyladenosine is a potent and selective inhibitor to study the role of adenosine receptors in various diseases, such as cancer, cardiovascular disorders and inflammatory conditions. It has the ability to modulate adenosine signaling pathways. Synonyms: 8-Bromo-adenosine 2',3',5'-Triacetate; 2',3',5'-Tri-O-acetyl-8-bromoadenosine; NSC 79212. Grades: 95%. CAS No. 31281-86-4. Molecular formula: C16H18BrN5O7. Mole weight: 472.25. | |
| 8-Bromo-2',3',5'-tri-O-acetylguanosine | 8-Bromo-2',3',5'-tri-O-acetylguanosine is an exquisitely intricate and exceptionally useful biochemical compound, tailored with intrinsic antiviral capabilities. It is revered for its profound potential in dissecting the intricate dynamics of viral RNA-dependent RNA polymerases. Synonyms: 8-Bromo-guanosine 2',3',5'-Triacetate; 2',3',5'-Tri-O-acetyl-8-bromoguanosine; NSC 174056; NSC 79210. Grades: 98%. CAS No. 15717-45-0. Molecular formula: C16H18BrN5O8. Mole weight: 488.25. | |
| 8-Bromo-2',5'-pAp | 8-Bromo-2',5'-pAp, a nucleotide analog, is widely applied as a substrate in enzymatic assays to explore RNA polymerase and RNA ligase abilities. Its versatility extends to the development of modified RNA molecules that serve as valuable tools in numerous biomedical fields. These applications include gene therapy for malignancies and genetic dysfunctions. Synonyms: (8Br-2',5'-pAp); 8-Bromo-adenosine-2',5'-bisphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H14BrN5O10P2 (free acid). Mole weight: 506.10 (free acid). | |
| 8-Bromo-2'-deoxyadenosine | It is a brominated DNA adduct produced by human DNA polymerases. Synonyms: 8-Bromo-9-(2'-deoxyribofuranosyl)adenine; 8-Bromodeoxyadenosine; NSC 79220; (2R,3S,5R)-5-(6-Amino-8-bromo-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol; 2'-Deoxy-8-bromoadenosine. Grades: ≥98% by HPLC. CAS No. 14985-44-5. Molecular formula: C10H12BrN5O3. Mole weight: 330.14. | |
| 8-Bromo-2'-deoxyguanosine | 8-Bromo-2'-deoxyguanosine is a fundamental constituent in compound assuming a crucial role in the exploration and development of antivirals. this compound serves as an elemental building block for nucleoside analogues employed in studying an array of ailments such as herpes, hepatitis B and human immunodeficiency virus (HIV). Synonyms: 8-Bromo-2'-deoxy-guanosine; NSC 105830; 2-Amino-8-bromo-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 8-Bromo-2'-dG; 8-Br-2'-dG; 8-Bromodeoxyguanosine; 8-Bromo-2'-deoxy-D-guanosine. Grades: ≥98% by HPLC. CAS No. 13389-03-2. Molecular formula: C10H12BrN5O4. Mole weight: 346.14. | |
| 8-Bromo-2'-deoxy-N2-DMF-5'-O-DMT-guanosine 3'-CE phosphoramidite | 8-Bromo-2'-deoxy-N2-DMF-5'-O-DMT-guanosine 3'-CE phosphoramidite is a cutting-edge synthetic compound based on guanosine, effectively incorporating 8-bromo modification and DMF-5'-O-DMT protection into guanosine residuals while carrying out oligonucleotide research and development. Synonyms: 5'-Dimethoxytrityl-N2-dimethylaminomethylidene-8-bromo-2'-deoxyGuanosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 8-Br-dG-CE Phosphoramidite; 8-Bromo-N2-DMF-5'-O-DMT-2'-deoxyguanosine 3'-CE phosphoramidite. CAS No. 198080-37-4. Molecular formula: C43H52N8O7PBr. Mole weight: 903.9. | |
| 8-Bromo-2'-deoxy-N6-DMF-5'-O-DMT-adenosine 3'-CE phosphoramidite | 8-Bromo-2'-deoxy-N6-DMF-5'-O-DMT-adenosine 3'-CE phosphoramidite is an imperative compound, serving as an indispensable phosphorylation recompound engendering the amalgamation of oligonucleotides. Its pervasive utilization in the research of pharmacological exploration, primarily within the domain of nucleotide-based therapeutics spanning antisense oligonucleotides and siRNA. Synonyms: 8-Bromo-2'-deoxy-N6-DMF-5'-O-DMT-D-adenosine 3'-CE phosphoramidite; 8-Bromo-N6-DMF-5'-O-DMT-2'-deoxyadenosine 3'-CE phosphoramidite. Molecular formula: C43H52BrN8O6P. Mole weight: 887.82. | |
| 8-Bromo-3'-deoxy-3'-fluoroguanosine | 8-Bromo-3'-deoxy-3'-fluoroguanosine, an intriguing biomedical compound, holds immense potential in the realm of antiviral drug research and development. Its proven efficacy against formidable viruses such as herpes simplex and human immunodeficiency virus (HIV) fuels scientific curiosity. By delving into the enzymatic activities, mechanisms, and inhibition of viral replication, this compound serves as a vital tool driving progress in the field of antiviral therapeutics. Synonyms: 2-amino-8-bromo-9-[(2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one. Grades: ≥95%. CAS No. 847649-50-7. Molecular formula: C10H11BrFN5O4. Mole weight: 364.13. | |
| 8-Bromo-3'-deoxyguanosine | 8-Bromo-3'-deoxyguanosine is a remarkable and robust antiviral compound, finding extensive application in research of viral infections, especially those of DNA origin. Synonyms: 2-amino-8-bromo-9-[(2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one. Grades: ≥95%. CAS No. 847649-68-7. Molecular formula: C10H12BrN5O4. Mole weight: 346.14. | |
| 8-Bromo-5'-O-[(4-cyanophenyl)methyl]-2',3'-di-O-(1-methylethylidene)adenosine | 8-Bromo-5'-O-[(4-cyanophenyl)methyl]-2',3'-di-O-(1-methylethylidene)adenosine is a remarkable pharmaceutical compound with anti-inflammatory and immunomodulatory attributes. Potential applications include the research of various inflammatory ailments like rheumatoid arthritand asthma. Synonyms: 8-Bromo-5'-O-(4-cyanobenzyl)-2',3'-di-O-isopropylidene adenosine; 4-[[(3aR,4R,6R,6aR)-4-(6-amino-8-bromopurin-9-yl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]methoxymethyl]benzonitrile; Adenosine, 8-bromo-5'-O-[(4-cyanophenyl)methyl]-2',3'-O-(1-methylethylidene)-. Grades: ≥95%. CAS No. 1134156-53-8. Molecular formula: C21H21BrN6O4. Mole weight: 501.33. | |
| 8-Bromo-5'-O-(dimethoxytrityl)-N6-(dimethylaminomethylidene)-2'-deoxyadenosine | 8-Bromo-5'-O-(dimethoxytrityl)-N6-(dimethylaminomethylidene)-2'-deoxyadenosine, a chemical compound utilized in the production of antiviral and anticancer drugs, has been found to selectively impede the replication of herpes simplex virus and stunt the expansion of cancer cells by hindering their DNA synthesis. Its specificity in targeting these entities makes it a valuable player in the medical field. Its multifaceted properties offer advancements in the development of novel treatments. CAS No. 207906-53-4. Molecular formula: C34H35BrN6O5. Mole weight: 687.60. | |
| 8-Bromo-9-(b-D-xylofuranosyl)guanine | 8-Bromo-9-(b-D-xylofuranosyl)guanine is an extraordinary antiviral compound bestowed with remarkable potentiality for research of viral infections, specifically focused on herpes viruses. By selectively concentrating on the viral DNA polymerase, it effectively restrains viral DNA enhancement. Synonyms: 6H-Purin-6-one, 2-amino-8-bromo-1,9-dihydro-9-β-D-xylofuranosyl-; 2-amino-8-bromo-9-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one; 8-bromguanosine; 2-Amino-8-bromo-9-(β-D-xylofuranosyl)-1,9-dihydro-6H-purin-6-one. Grades: ≥95%. CAS No. 1212650-12-8. Molecular formula: C10H12BrN5O5. Mole weight: 362.14. | |
| 8-Bromoadenosine | It is an adenosine binding inhibitor. Synonyms: 6-Amino-8-bromopurine Riboside; NSC 79213; 8-Bromo Adenosine; (2R,3R,4S,5R)-2-(6-Amino-8-bromo-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; Bromoadenosine; 8-Bromo-adenosine; 8-Bromoadenine-9-β-D-ribofuranoside. Grades: ≥ 95 %. CAS No. 2946-39-6. Molecular formula: C10H12BrN5O4. Mole weight: 346.14. | |
| 8-Bromoadenosine 5'-Triphosphate Sodium Salt | 8-Bromoadenosine 5'-Triphosphate Sodium Salt is a reagent required for the characterization (stoichiometry, geometry, and stability constant) of ATP:Fe(II) complex. Synonyms: 8-Bromo-adenosine 5'-(Tetrahydrogen triphosphate) Sodium Salt. CAS No. 81035-56-5. Molecular formula: C10H15BrN5O13P3 x(Na). Mole weight: 586.08. | |
| 8-Bromo-AP2 (Nic) | 8-Bromo-AP2 (Nic) unlocks the potential for therapeutic intervention in multiple neurological disorders, including Alzheimer's disease and nicotine addiction, thanks to its potent and selective inhibitory effects on the nicotinic acetylcholine receptor. In addition to its clinical applications, this compound serves as a research tool for the in-depth study of nicotinic receptors within the complex biological framework of the brain. Synonyms: (8Br-AP2(Nic)); Nicotinamide 8-bromo-adenine dinucleotide, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C21H26BrN7O14P2 (free acid). Mole weight: 742.32 (free acid). | |
| 8-Bromo-AppNHp | 8-Bromo-AppNHp, a coveted biochemical compound, brimming with potential, is considered an integral tool in the unprecedented scientific endeavors to unravel the mysteries of signal transduction and protein activation pathways. Its significance lies in its extraordinary ability to emulate adenosine triphosphate (ATP), lending an unfiltered glimpse into the functional intricacies of G-proteins and adenylate cyclases. Its presence has revolutionized the world of medicinal research, opening new horizons in the quest to tackle both neurological disorders and cardiovascular diseases. Synonyms: (8Br-AppNHp, 8Br-AMPPNP); 8-Bromo-adenosine-5'-[(β,γ)-imido]triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H16N6O12P3Br (free acid). Mole weight: 585.09 (free acid). | |
| 8-Bromo-cAMP | 8-Bromo-cAMP is a cell-permeable cAMP analog that activates PKA. It inhibits cell growth, decreases proliferation, increases differentiation and induces apoptosis. Synonyms: (8Br-cAMP); 8-Bromo-adenosine-3',5'-cyclic monophosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 76939-46-3. Molecular formula: C10H11N5O6PBr (free acid). Mole weight: 408.10 (free acid). | |
| 8-Bromo-GDP | 8-Bromo-GDP is an exemplary and formidable analogue of guanosine diphosphate (GDP), facilitating the research of GTP-binding proteins and the mechanisms of signaling pathways, protein enmeshment and GTPase activity. Synonyms: (8Br-GDP); 8-Bromo-guanosine-5'-diphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H14N5O11P2Br (free acid). Mole weight: 522.09 (free acid). | |
| 8-Bromo-GMP | 8-Bromo-GMP is a compound used in biomedicine to study the effects of G protein-coupled receptor signaling and phosphodiesterase activity. It has also been studied for its anticancer properties due to its ability to induce cell death in various cancer cell lines. Additionally, 8-Bromo-GMP has been used to mimic the effects of nitric oxide signaling in biological processes. Synonyms: (8Br-GMP); 8-Bromo-guanosine-5'-monophosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H13N5O8PBr (free acid). Mole weight: 442.11 (free acid). | |
| 8-Bromo-GppNHp | 8-Bromo-GppNHp, a biochemical known for its role in investigating the signaling pathways of G proteins, is gaining notoriety in the field of biomedical research. Primarily, the product is utilized to study G protein-coupled receptors (GPCRs) and their downstream effectors. Beyond that, the research community has found it to be instrumental in studies related to various diseases -- among them cancer, cardiovascular afflictions, and diabetes. As the product continues to prove its worth, it is sure to remain an increasingly important tool for those in the field of biomedical science. Synonyms: (8Br-GppNHp, 8Br-GMPPNP); 8-Bromo-guanosine-5'-[(β,γ)-imido]triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H16N6O13P3Br (free acid). Mole weight: 601.09 (free acid). | |
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