BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| 8-Bromo-guanosine | 8-Bromo-guanosine, an extensively studied chemical entity, manifests remarkable potency in the realm of biomedicine owing to its ability to obstruct viral RNA synthesis. Synonyms: 8-Bromoguanosine; 2-Amino-8-bromo-6-hydroxypurine Riboside; NSC 174257; NSC 79211; 2-amino-8-bromo-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 8-Bromo-D-guanosine; 8-Bromo-9-β-D-ribofuranosylguanine. Grades: ≥98% by HPLC. CAS No. 4016-63-1. Molecular formula: C10H12BrN5O5. Mole weight: 362.14. |  |
| 8-Bromoinsine | 8-Bromoinsine is a remarkably powerful and bioactive compound, embodied within its molecular structure lies a potent antiviral potential, holding great application in restraining the proliferation of diverse viral strains. Synonyms: (2R,3R,4S,5R)-2-(8-bromo-6-hydroxy-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. Grades: 95%. CAS No. 55627-73-1. Molecular formula: C10H11BrN4O5. Mole weight: 347.12. | |
| 8-Bromo-N2-(dimethylaminomethylidene)-2'-deoxyguanosine | 8-Bromo-N2-(dimethylaminomethylidene)-2'-deoxyguanosine is a highly prized compound, holding immense value due to its noteworthy potential in studying tumors and viral drugs. This compound can be used to delve into the intricate repercussions of DNA impairment and the subsequent mechanisms involved in its reparation. Grades: ≥ 90%. CAS No. 717876-75-0. Molecular formula: C13H17BrN6O4. Mole weight: 401.21. | |
| 8-Bromo-N6-(dimethylaminomethylidene)-2'-deoxyadenosine | 8-Bromo-N6-(dimethylaminomethylidene)-2'-deoxyadenosine is an exceptionally powerful and discriminatory inhibitor, aiding through precise research within distinct enzymatic mechanisms. F. Synonyms: 8-BROMO-N6-(DIMETHYLAMINOMETHYLIDENE)-2'-DEOXYADENOSINE; N'-[8-bromo-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]-N,N-dimethylmethanimidamide. Grades: ≥ 95%. CAS No. 207906-52-3. Molecular formula: C13H17BrN6O3. Mole weight: 385.21. | |
| 8-Br-PET-cGMP Sodium Salt | 8-Br-PET-cGMP Sodium Salt is a pkG cell-permeable activator. Synonyms: 2-Bromo-3,4-dihydro-6-phenyl-3-(3,5-O-phosphinico-β-D-ribofuranosyl)-9H-imidazo[1,2-a]purin-9-one Sodium Salt. CAS No. 185246-29-1. Molecular formula: C18H14BrN5NaO7P. Mole weight: 546.2. | |
| 8-Br-Xao | 8-Br-Xao, the intriguing research chemical, has gained traction in the biomedical industry for investigating its potential for treating cancer and inflammation. With promising results, it appears to be able to tamper with the activity of crucial enzymes and pathways involved in progressing diseases. Therefore, this compound holds intrigue as a potential drug for treating relevant conditions and is expected to involve further study and development. CAS No. 3001-46-6. Molecular formula: C10H11BrN4O6. Mole weight: 363.1. | |
| 8-CEA-Ado | 8-CEA-Ado is a reactive precursor for immobilisation. Synonyms: 8- Carboxyethylaminoadenosine. Grades: ≥ 97 % by HPLC. CAS No. 1161916-63-8. Molecular formula: C13H18N6O6. Mole weight: 364.3. | |
| 8-Chloro-2'-beta-C-methylinosine | 8-Chloro-2'-beta-C-methylinosine, a remarkable compound in the biomedical industry, serves as a powerful antiviral agent. Its efficacy knows no bounds, effectively thwarting the replication of RNA viruses like Zika virus and Hepatitis C. By skillfully targeting viral RNA synthesis and translation, this compound proves its inhibitory potential. Grades: ≥95%. CAS No. 1106012-39-8. Molecular formula: C11H13ClN4O5. Mole weight: 316.70. | |
| 8-Chloro-2'-deoxy-2'-fluoroinosine | 8-Chloro-2'-deoxy-2'-fluoroinosine is a renowned pharmaceutical compound extensively utilized in the biomedical sector, showcasing profound antiviral attributes. Its dominant application pertains to studying the scourge of viral infections induced by the notorious herpes simplex virus, varicella-zoster virus and Epstein-Barr virus. Grades: ≥95%. Molecular formula: C10H10ClFN4O4. Mole weight: 304.66. | |
| 8-Chloro-2'-deoxyadenosine | 8-Chloro-2'-deoxyadenosine is an extensively researched synthetic compound, prominently finding application in studying chronic lymphocytic leukemia (CLL). Operating via its profound interference with the replication process, this remarkable compound exhibits inhibition in restraining the pernicious proliferation of cancerous cells. Synonyms: (2R,3S,5R)-5-(6-amino-8-chloro-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol; Adenosine, 8-chloro-2'-deoxy-; 8-Chloro-2'-deoxy-D-adenosine; 8-Cl-d-Ado. Grades: ≥95%. CAS No. 85562-55-6. Molecular formula: C10H12ClN5O3. Mole weight: 285.69. | |
| 8-Chloro-2'-O-methylinosine | 8-Chloro-2'-O-methylinosine, an essential compound for the advancement of antiviral medications, plays a pivotal role in combating diverse viral infections including hepatitis C and respiratory syncytial virus (RSV). By impeding viral replication and leveraging its robust antiviral capabilities, this compound effectively aids in the management of these ailments. Grades: ≥95%. Molecular formula: C11H13ClN4O5. Mole weight: 316.70. | |
| 8-Chloroadenosine | 8-Chloroadenosine is an analog of adenosine. It is metabolized in vivo to 8-Chloro-ATP. It depletes ATP and inhibits tumor growth in hematological malignancies. It also inhibits tumor growth in lung and breast cancer cell lines. It incorporates into RNA during transcription and inhibits RNA synthesis. It mitotics catastrophe and induces G2/M cell cycle arrest in A549 and H1299 cells. It is a useful research chemical and has cytotoxicity effects. Synonyms: 6-Amino-8-chloropurine riboside; 8-Cl-Ado; 8-Chloro-adenosine; (2R,3R,4S,5R)-2-(6-amino-8-chloro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 8-Chloro-D-adenosine. Grades: ≥98% by HPLC. CAS No. 34408-14-5. Molecular formula: C10H12ClN5O4. Mole weight: 301.69. | |
| 8-Chloroadenosine 3',5'-Cyclic Monophosphate | 8-Chloroadenosine 3',5'-Cyclic Monophosphate is a cAMP analog with high selectivity for PKA I. Used in anti-cancer treatments. Uses: Antineoplastic agents. Synonyms: 8-Chloro-cAMP; 8-Chloro-cyclic AMP; 8-Chloroadenosine 3',5'-Cyclic Monophosphate; 8-Chloroadenosine 3',5'-Cyclic Phosphate; Adenazole; NSC 284751; NSC 614491; Tocladesine. Grades: 95%. CAS No. 41941-56-4. Molecular formula: C10H11ClN5O6P. Mole weight: 363.65. | |
| 8-Chloroinosine | A major metabolite of 8-Chloroadenosine. Synonyms: 8-Chloro-inosine; 8-Cl-I; (2R,3R,4S,5R)-2-(8-Chloro-6-hydroxy-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 8-Chloro-D-inosine; 9H-Purin-6-ol, 8-chloro-9-β-D-ribofuranosyl-. Grades: ≥95%. CAS No. 116285-77-9. Molecular formula: C10H11ClN4O5. Mole weight: 302.67. | |
| 8-Cl-2'-FDA-AEC-cAMP | 8-Cl-2'-FDA-AEC-cAMP is an extraordinary cyclic AMP analogue, emerging as an exquisite research tool within the biomedical sphere. Its versatile nature leads to unravelling the enigmatic cAMP-dependent signalling pathways and illuminating the intricate world of signal transduction. Synonyms: 8- Chloro- 2'- O- (fluoresceindiacetate- (2- aminoethylcarbamoyl))adenosine- 3', 5'- cyclic monophosphate. | |
| 8-Cl-Ado | 8-Cl-Ado is a cytotoxic metabolite of 8-chloro cyclic AMP. Synonyms: 8- Chloroadenosine. Grades: ≥ 98% by HPLC. CAS No. 34408-14-6. Molecular formula: C10H12ClN6O4. Mole weight: 301.7. | |
| 8-Cl-ATP | 8-Cl-ATP is a corresponding triphosphate form for research on 8-chloro cAMP and 8-Cl-adenosine. Synonyms: 8- Chloroadenosine- 5'- triphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 185341-71-3. Molecular formula: C10H15ClN5O13P3 (free acid). Mole weight: 541.6 (free acid). | |
| 8-Cl-cAMP | 8-Cl-cAMP is a selective cAMP analogue preferring protein kinase A type I. 8-Cl-cAMP has already been in several clinical trials to identify its inhibitory effect of growth and differentiation in cultured cancer cell lines. Synonyms: 8- Chloroadenosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 124705-03-9. Molecular formula: C10H10ClN5O6P · Na. Mole weight: 385.6. | |
| 8-Cl-cAMP-AM | 8-Cl-cAMP-AM is a precursor of 8-Cl-cAMP, the PKA activator. The polar active analogue is released after the metabolism of 8-Cl-cAMP-AM by esterases. Synonyms: 8- Chloroadenosine- 3', 5'- cyclic monophosphate, acetoxymethyl ester. Grades: ≥ 97% by HPLC for mixture of isomers. Molecular formula: C13H15ClN5O8P. Mole weight: 435.7. | |
| 8-Cl-c-diAMP | 8-Cl-c-diAMP is an analogue of c-diAMP, the bacterial second messenger, which is used for binding studies and precursor for further modifications with spacers or labels. Synonyms: 8- Chloro- cyclic diadenosine monophosphate, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C20H23ClN10O12P2 (free acid). Mole weight: 692.9 (free acid). | |
| 8-Cl-dAdo | 8-Cl-dAdo is a formidable and discriminating inhibitory compound, enthralling the enzyme ribonucleotide reductase. Synonyms: 8- Chloro- 2'- deoxyadenosine. Grades: ≥ 96% by HPLC. CAS No. 86662-66-6. Molecular formula: C10H12ClN6O3. Mole weight: 286.7. | |
| 8-Cl-dGuo | 8-Cl-dGuo, an anti-RNA virus crusader, is a nucleoside of robust antiviral power. Employed in treating life-threatening hepatitis C and coronavirus, it exercises the incredible ability of obstructing viral RNA replication. With a track record of reining in multiple viral strains, 8-Cl-dGuo, thanks to its singular structural features, is a forerunner in directing medicines to infected cells, shielding healthy tissues from toxicity. Synonyms: 8- Chloro- 2'- deoxyguanosine. Grades: ≥ 96% by HPLC. CAS No. 437716-62-3. Molecular formula: C10H12ClN6O4. Mole weight: 301.7. | |
| 8-Cl-Ino | 8-Cl-Ino is the potential metabolite of 8-chloro cyclic AMP and 8-chloroadenosine. Synonyms: 8- Chloroinosine. Grades: ≥ 98% by HPLC. CAS No. 116286-77-9. Molecular formula: C10H11ClN4O6. Mole weight: 302.7. | |
| 8-CPT-cAMP | 8-CPT-cAMP is an activator of cAMP- and cGMP-dependent protein kinase and of Epac. It has an improved membrane permeability, phosphodiesterase stability and selectivity for site B of cAK type II. Uses: Enzyme inhibitors. Synonyms: 8- (4- Chlorophenylthio)adenosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 93882-12-3. Molecular formula: C16H14ClN5O6PS · Na. Mole weight: 493.8. | |
| 8-[DY-547]-AET-2'-O-Me-cAMP | 8-[DY-547]-AET-2'-O-Me-cAMP is a fluorescent activator (λexc557 nm, λem574 nm) of the exchange protein activated by cAMP (Epac) or cAMP-GEF. Synonyms: 8-(2-[DY-547]-aminoethylthio)-2'-O-methyladenosine-3',5'-cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. Molecular formula: C43H51N8Na2O13PS3. Mole weight: 1061.1. | |
| 8-[DY-547]-AET-cAMP | 8-[DY-547]-AET-cAMP is a fluorescent cAMP analogue (λexc 557 nm, λem 574 nm). It can be used for research focussed on activation studies of HCN2 channels and other cAMP-responsive binding proteins detailed technical information available. Synonyms: 8-(2-[DY-547]-aminoethylthio)adenosine-3',5'-cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. Molecular formula: C42H49N8Na2O13PS3. Mole weight: 1047.1. | |
| 8-[DY-547]-AET-cGMP | 8-[DY-547]-AET-cGMP is a fluorescent cGMP analogue (λexc557 nm, λem574 nm). It can be used for kinetic studies of CNG ion channels and other cGMP-reponsive binding proteins. Synonyms: 8-(2-[DY-547]-aminoethylthio)guanosine-3',5'-cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. Molecular formula: C42H49N8Na2O14PS3. Mole weight: 1063. | |
| 8-[DY-647]-AET-cGMP | 8-[DY-647]-AET-cGMP is a fluorescent cGMP analogue (λexc649 nm, λem666 nm). It can be used for kinetic studies of CNG ion channels and other cGMP-reponsive binding proteins. Synonyms: 8-(2-[DY-647]-aminoethylthio)guanosine-3',5'-cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. Molecular formula: C44H51N8Na2O14PS3. Mole weight: 1089.1. | |
| 8-[Fluo]-AHT-PET-cGMP | 8-[Fluo]-AHT-PET-cGMP is a fluorescent cGMP analogue (λexc494 nm, λem517 nm), which can be used for receptor studies. It has the potential to be a CNG channel inhibitor. Synonyms: 8-(6-[Fluoresceinyl]aminohexylthio)-β-phenyl-1,N2-ethenoguanosine-3',5'-cyclic monophosphate, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C45H39N7NaO12PS2. Mole weight: 987.9. | |
| 8-[Fluo]-cGMP | 8-[Fluo]-cGMP is a fluorescent cGMP analogue (λexc494 nm, λem517 nm). Synonyms: 8- (2-[Fluoresceinyl]aminoethylthio) guanosine-3', 5'-cyclic monophosphate, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C33H27N7NaO12PS2. Mole weight: 831.7. | |
| 8-Fluoroadenosine | 8-Fluoroadenosine is an extraordinary compound, acting as a highly selective inhibitor of S-adenosylhomocysteine hydrolase (SAHH) within the dynamic realm of cellular biochemistry. Synonyms: 8-fluoro-adenosine; (2R,3R,4S,5R)-2-(6-Amino-8-fluoro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. CAS No. 23205-67-6. Molecular formula: C10H12FN5O4. Mole weight: 285.23. | |
| 8-HA-cAMP | 8-HA-cAMP is a selective analogue of cAMP preferring site B of PKA I. It has high membrane permeability and superior stability towards phosphodiesterases. Synonyms: 8- Hexylaminoadenosine- 3', 5'- monophosphate, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 59212-44-1. Molecular formula: C16H24N6O6P · Na. Mole weight: 450.4. | |
| 8-Hydroxy-3'-deoxy-3'-fluoroguanosine | 8-Hydroxy-3'-deoxy-3'-fluoroguanosine is a profoundly potent antiviral compound widely applied in the biomedical domain, exbiting formidable inhibitory attributes in research of viral infections, encompassing influenza and herpes. Its intrinsic mechanism revolves around perturbing viral replication processes. Grades: ≥95%. Molecular formula: C10H12FN5O5. Mole weight: 301.23. | |
| 8-Hydroxy-3'-deoxyguanosine | 8-Hydroxy-3'-deoxyguanosine, a vital biomarker in the field of biomedicine, assumes a pivotal role in the investigation of oxidative DNA damage. Renowned for its applicability in assessing and diagnosing ailments associated with oxidative stress, including cancer, cardiovascular diseases, neurodegenerative disorders, and aging, this product proves invaluable. Grades: ≥95%. Molecular formula: C10H13N5O5. Mole weight: 283.24. | |
| 8-Hydroxyguanine | A crucial nucleotide derivative, 8-Hydroxyguanine, reigns supreme in the biomedical industry for its multifaceted functions. Serving as a DNA damage biomarker for several human diseases, including cancer, it plays a significant role in furthering our understanding of complicated cellular mechanisms. Moreover, its use in research facilitates the evaluation of the efficacy of certain chemotherapy drugs, greatly assisting the development of effective cancer treatments. A product of immense importance, 8-Hydroxyguanine is the key to unlocking the mysteries of DNA repair mechanisms and expanding the frontiers of medical science. Uses: An 8-oxo-guanine repair pathway coordinated by mutyh glycosylase and dna polymerase &lambda. Synonyms: 2-Amino-6,8-purinediol; 8-Oxo-7,8-dihydroguanine; NSC 22720; 2-Amino-6,8-dihydroxypurine; 7,8-dihydro-8-oxoguanine; 2-Aminopurine-6,8-diol; 2-amino-7,9-dihydro-3H-purine-6,8-dione. Grades: ≥95% by HPLC. CAS No. 5614-64-2. Molecular formula: C5H5N5O2. Mole weight: 167.13. | |
| 8-Hydroxymethylguanosine | 8-Hydroxymethylguanosine is a potent biomedical compound, exhibiting immense promise in studying neurodegenerative adversaries such as the notorious Alzheimer's and Parkinson's diseases. Synonyms: Guanosine, 8-(hydroxymethyl)-. Grades: ≥95%. CAS No. 54898-41-8. Molecular formula: C11H15N5O6. Mole weight: 313.27. | |
| 8-Hydroxy-xyloguanosine | 8-Hydroxy-xyloguanosine is a biomedically important compound widely used in the research and development of various pharmaceutical drugs. It serves as a key intermediate for synthesizing nucleotide analogs that target viral diseases, such as hepatitis C and respiratory syncytial virus. Its unique structure makes it a crucial component for studying antiviral agents and designing potential therapeutics to combat these infectious diseases effectively. Synonyms: 2-amino-9-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-(hydroxy)-1H-purin-6-one. Grades: ≥95%. Molecular formula: C10H13N5O6. Mole weight: 299.24. | |
| 8-Iodoadenosine | 8-Iodoadenosine, a biomedical product, has emerged as a pivotal intervention for diverse ailments and medical circumstances. This compound exhibits exceptional prospects in oncological investigations, particularly pertaining to the innovation of avant-garde anticancer modalities. Profoundly impeding cellular mechanisms, it manifests as a strong suppressor of cancerous cell propagation whilst concurrently instigating apoptosis. Synonyms: 8-Indoo adenosine. Grades: 97%. CAS No. 31281-88-6. Molecular formula: C10H12IN5O4. Mole weight: 393.14. | |
| 8-Iodo-ADP | 8-Iodo-ADP is a remarkable biomedical compound unlocking the enigmatic realm of purinergic receptors, unraveling their binding mechanics and activating potential. Synonyms: (8I-ADP); 8-Iodo-adenosine-5'-diphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H14N5O10P2I (free acid). Mole weight: 553.10 (free acid). | |
| 8-Iodo-AppNHp | 8-Iodo-AppNHp - a renowned biochemical reagent - finds widespread usage in the G protein-coupled receptor (GPCR) study arena. Its non-hydrolyzable analog of GTP ensures sturdy receptor-G protein complexes, enabling downstream signaling pathway investigations. Apart from resolving cardiovascular illnesses and cancer investigations, it has contributed to various other GPCR studies. Synonyms: (8I-AppNHp, 8I-AMPPNP); 8-Iodo-adenosine-5'-[(β,γ)-imido]triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H16N6O12P3I (free acid). Mole weight: 632.09 (free acid). | |
| 8-Iodo-ATP | 8-Iodo-ATP is a potent and specific agonist for P2X receptors, which are involved in various pathophysiological processes such as pain perception and inflammation. It is widely used in the biomedical industry to study the function and regulation of P2X receptors and to develop new drugs targeted at these receptors for the research of chronic pain, neuroinflammatory disorders and other conditions. Synonyms: (8I-ATP); 8-Iodo-adenosine-5'-triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 82049-15-8. Molecular formula: C10H15N5O13P3I (free acid). Mole weight: 633.08 (free acid). | |
| 8-Iodo-GDP | 8-Iodo-GDP, a nucleotide analog, facilitates in the study of molecular mechanisms of signal transduction with promising applications in cancer therapies. Along with its ability to inhibit assembly and disassembly of the microtubule network,it has also garnered significant attention for its potential in treating neurological diseases, including Alzheimer's and Huntington's. Synonyms: (8I-GDP); 8-Iodo-guanosine-5'-diphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H14N5O11P2I (free acid). Mole weight: 569.10 (free acid). | |
| 8-Iodo-GppNHp | 8-Iodo-GppNHp, a chemical compound employed in biomedicine to inquire into G-protein signaling pathways, often functions as a non-hydrolyzable GTP analog, providing a means of exploring the activity of G-protein coupled receptors and their associated downstream effectors and target proteins. Its application has examined various afflictions, such as cancer and neurological disorders, advancing our understanding of these conditions. Synonyms: (8I-GppNHp, 8I-GMPPNP); 8-Iodo-guanosine-5'-[(β,γ)-imido]triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H16N6O13P3I (free acid). Mole weight: 648.09 (free acid). | |
| 8-Iodo-GTP | 8-Iodo-GTP, a modified nucleotide, serves as a guanine nucleotide-binding proteins (G proteins) substrate for biochemical research. Its highly selective incorporation into G proteins allows for the investigation of their interactions with enzymes and receptors. Furthermore, researchers have studied its potential efficacy in the treatment of cancer. Synonyms: (8I-GTP); 8-Iodo-guanosine-5'-triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 1071796-43-4. Molecular formula: C10H15N5O14P3I (free acid). Mole weight: 649.07 (free acid). | |
| 8-Iodo-guanosine | 8-Iodo-guanosine, a chemical compound used in biomedical research, has proven instrumental in studying the impacts of purine nucleoside analogs on cancers and viral infections. As an iodine-substituted guanosine derivative, it exhibits the potential to act as an inhibitor of RNA viruses like HIV and hepatitis C. Synonyms: 8-iodoguanosine; 8-I-rG; 2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-8-iodo-1H-purin-6(9H)-one; 8-iodocoumarin. Grades: ≥97% by HPLC. CAS No. 18438-99-8. Molecular formula: C10H12IN5O5. Mole weight: 409.14. | |
| 8-MABA-cAMP | 8-MABA-cAMP is a fluorescent cAMP analogue (λexc352 nm, λem436 nm). Synonyms: 8- (4- [N- Methylanthraniloyl]aminobutylamino) adenosine- 3', 5'- monophosphate, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 909782-76-9. Molecular formula: C22H28N8O7P · Na. Mole weight: 570.5. | |
| 8-MA-cAMP | 8-MA-cAMP is a selective cAMP analogue that has affinity to site B of protein kinase A type I and II. Site A activity is developed when 8-MA-cAMP acts synergistically together with other analogues. Synonyms: 8- Methylaminoadenosine- 3', 5' cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 33823-18-6. Molecular formula: C11H14N6O6P · Na. Mole weight: 380.2. | |
| 8-MBT-cAMP | 8-MBT-cAMP is a cAMP analogue used for immobilization as an affinity ligand or for coupling of labelling structures such as fluorophores. Synonyms: 8- (4- Mercaptobutylthio)adenosine- 3', 5' cyclic monophosphate, triethyl ammonium salt. Grades: ≥ 98% by HPLC. CAS No. 1033893-75-2. Molecular formula: C14H20N5O6PS2 (free acid). Mole weight: 449.4 (free acid). | |
| 8-Methyaminoadenosine | 8-Methyaminoadenosine is a potent purinergic receptor agonist that is used in the biomedical industry for the treatment of various neurological disorders including Parkinson's disease and epilepsy. It acts as a neurotransmitter and modulates the release of dopamine, reducing motor symptoms associated with Parkinson's disease. Synonyms: 9H-Purine, 6-amino-8-(methylamino)-9-β-D-ribofuranosyl-; Adenosine, 8-(methylamino)-; (2R,3R,4S,5R)-2-(6-amino-8-(methylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 8-(methylamino)adenosine. Grades: ≥95%. CAS No. 13389-13-4. Molecular formula: C11H16N6O4. Mole weight: 296.28. | |
| 8-Methyl-2'-deoxyadenosine | 8-Methyl-2'-deoxyadenosine is an intricately engineered derivative of adenosine, unveiling prodigious potential in obstructing the unrelenting growth of neoplastic cells, thereby holding promise in research of specific cancers. Synonyms: Adenosine, 2'-deoxy-8-methyl-; 2'-deoxy-8-methyladenosine; (2R,3S,5R)-5-(6-Amino-8-methyl-purin-9-yl)-2-hydroxymethyl-tetrahydro-furan-3-ol. Grades: ≥95%. CAS No. 85562-60-3. Molecular formula: C11H15N5O3. Mole weight: 265.27. | |
| 8-Methyl-2'-deoxyguanosine | 8-Methyl-2'-deoxyguanosine is an invaluable compound assuming a pivotal function in the amalgamation of curative substances catering to the research of viral ailments such as hepatitis C and HIV. Synonyms: Guanosine, 2'-deoxy-8-methyl-; 2'-Deoxy-8-methylguanosine; 2-Amino-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-8-methyl-1H-purin-6(9H)-one. Grades: ≥95%. CAS No. 85819-69-8. Molecular formula: C11H15N5O4. Mole weight: 281.27. | |
| 8-Methyladenosine | 8-Methyladenosine, a nucleoside present in diverse organisms' RNAs, holds significance in multiple biological processes, such as gene expression, mRNA stability, and translation regulation. Studies indicate that 8-Methyladenosine's aberrant expression associates with numerous ailments like viral infection, neurodegenerative disorders, and cancer, expediting the development of newer therapies. Synonyms: 8-Methyl Ado; 8-Methyl adenosine; Adenosine, 8-methyl-; (2R,3R,4S,5R)-2-(6-Amino-8-methyl-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. Grades: ≥95%. CAS No. 56973-12-7. Molecular formula: C11H15N5O4. Mole weight: 281.27. | |
| 8-Methylguanosine | 8-Methylguanosine is a crucial compound in biomedicine used for research purposes. It serves as a building block in the synthesis of nucleic acids and is commonly used in studies investigating RNA metabolism and epitranscriptomics. Synonyms: monomethylguanosine; 2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-8-methyl-1H-purin-6(9H)-one. Grades: ≥95%. CAS No. 36799-17-4. Molecular formula: C11H15N5O5. Mole weight: 297.27. | |
| 8-Morpholinyl-GTP | 8-Morpholinyl-GTP, a biochemical known for its role in G protein signaling, has gained popularity in scientific research to examine the etiology of several ailments. Studies exploring Parkinson's, Huntington's, and Alzheimer's diseases and cancer have utilized this compound due to its unique composition and performance. Researchers find its presence instrumental in determining molecular mechanisms of these diseases and uncovering effective treatment options. Synonyms: 8-Morpholinyl-guanosine-5'-triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C14H23N6O15P3 (free acid). Mole weight: 608.28 (free acid). | |
| 8-N3-6-Biotin-10-cAMP | 8-N3-6-Biotin-10-cAMP is an analogue in photoaffinity labelling of cAMP binding proteins which can be immobilized by UV light. Grades: ≥ 98% by HPLC. Molecular formula: C28H40N12O9PS · Na. Mole weight: 774.7. | |
| 8-N3-6-[DY-547]-AE-cAMP | 8-N3-6-[DY-547]-AE-cAMP is a photosensitive analogue for photoaffinity labelling. It can be immobilized by irradiation of UV light. Synonyms: 8-Azido-N6-(2-[DY-547]-aminoethyl)adenosine-3',5'-cyclic monophosphate, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C42H48N11Na2O13PS2. Mole weight: 1056. | |
| 8-N3-cAMP | 8-N3-cAMP is an analogue of cAMP binding proteins used for photoaffinity labelling. Uses: Affinity labels. Synonyms: 8- Azidoadenosine- 3', 5'-cyclic monophosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 31966-52-6. Molecular formula: C10H10N8O6P · Na. Mole weight: 392.2. | |
| 8-N3-ε-ADP | 8-N3-ε-ADP is a 8-N3-ADP analogue with photosensitive activity and a ε-ADP analogue with fluorescent property, which is used for photoaffinity labelling of ADP binding proteins and subsequent detection of the fluorescent label (λexc285 nm, λem410 nm). Synonyms: 8- Azido- 1, N6- ethenoadenosine- 5'- O- diphosphate, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C12H15N8O10P2 (free acid). Mole weight: 493.3 (free acid). | |
| 8-N3-ε-ATP | 8-N3-ε-ATP is a photosensitive analogue of 8-N3-ATP as well as a fluorescent analogue of ε-ATP, which can be used for photoaffinity labelling of ATP binding proteins and subsequent detection of the fluorescent label (λexc285 nm, λem412 nm). Synonyms: 8- Azido- 1, N6- ethenoadenosine- 5'- O- triphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 66895-05-4. Molecular formula: C12H15N8O13P3 (free acid). Mole weight: 572.2 (free acid). | |
| 8-Nitroguanosine | A highly reactive redox-active nucleic acid derivative that is formed in cellular RNA as biomarker of exposure to reactive nitrogen species. Recent studies suggest that it might contribute to the pathogenesis of inflammation-associated carcinogenesis. Synonyms: 8-Nitro-D-guanosine; 2-imino-8-nitro-9-(beta-D-ribofuranosyl)-3,9-dihydro-2H-purin-6-ol; 2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-8-nitro-1H-purin-6(9H)-one. Grades: ≥95%. CAS No. 337536-53-5. Molecular formula: C10H12N6O7. Mole weight: 328.24. | |
| 8-(N,N-Dimethylaminomethyl)guanosine | 8-(N,N-Dimethylaminomethyl)guanosine is a profound compound, aiding in studying the unparalleled menace of herpes simplex virus (HSV) and human cytomegalovirus (HCMV). Grades: ≥95%. Molecular formula: C13H20N6O5. Mole weight: 340.34. | |
| 8-NO2-Guo | 8-NO2-Guo is used for analysis of hydrolysates of RNA stressed by nitric oxide/superoxide and peroxynitrite. Synonyms: 8- Nitroguanosine. Grades: ≥ 98% by HPLC. CAS No. 337636-63-6. Molecular formula: C10H12N6O7. Mole weight: 328.3. | |
| 8-OH-2'-O-Me-cAMP | 8-OH-2'-O-Me-cAMP is an activator of the exchange protein activated by cAMP (Epac) or cAMP-GEF, which does not activate protein kinase A. It can be used in patch clamp applications. Synonyms: 8- Hydroxy- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. Molecular formula: C11H13N5O7P · Na. Mole weight: 381.2. | |
| 8-OH-Ado | 8-OH-Ado is used for analysis of oxidative/radioactive stress RNA hydrolysates. Synonyms: 8- Hydroxyadenosine. Grades: ≥ 97% by HPLC. CAS No. 29861-67-8. Molecular formula: C10H13N6O6. Mole weight: 283.3. | |
| 8-OH-cAMP | 8-OH-cAMP is a polar analogue of cAMP used for the study of extracellular cAMP receptors. When applied by patch clamp techniques, 8-OH-cAMP remains trapped inside the cell. It exhibits a resistant effect of mammalian cyclic nucleotide-dependent phosphodiesterases. Synonyms: 8- Hydroxyadenosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 31356-95-3. Molecular formula: C10H11N5O7P · Na. Mole weight: 367.2. | |
| 8-Oxo-2'-deoxyguanosine | 8-Oxo-2'-deoxyguanosine is a crucial biomarker to evaluate oxidative DNA damage in research of related diseases such as cancer and neurodegenerative disorders. It is an oxidized nucleoside known for its ability to accurately measure the level of oxidative stress. Synonyms: 8-Oxo-dG; 8-Hydroxy-2'-deoxyguanosine; 8-Hydroxydeoxyguanosine. Grades: ≥ 98%. CAS No. 88847-89-6. Molecular formula: C10H13N5O5. Mole weight: 283.24. | |
| 8-Oxoadenosine | It is an anticancer antibiotic, oxidized nucleic acid adduct and phosmidosine precursor (P-prodrug). It can be used to treat hemochromatosis. Synonyms: NSC 102240; NSC 90396; 7,8-Dihydro-8-oxoadenosine; 8-Hydroxyadenosine; 8-Oxo-7,8-dihydroadenosine; 6-Amino-7,9-dihydro-9-β-D-ribofuranosyl-8H-purin-8-one; 6-amino-9-(beta-D-ribofuranosyl)purin-8-(7H)-one; (2R,3R,4S,5R)-2-(6-amino-8-hydroxy-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 8-Hydroxyadenosine. Grades: ≥95%. CAS No. 29851-57-8. Molecular formula: C10H13N5O5. Mole weight: 283.24. | |
| 8-Oxo-dATP | 8-Oxo-dATP is a nucleotide analog mainly acting as a substrate for DNA polymerase during DNA enhancement and repair. 8-Oxo-dATP is involved in cellular processes related to oxidative stress and DNA damage. It can be used to study the effects of oxidative DNA damage and its association with diseases such as cancer and neurodegenerative disorders. Synonyms: 8-Oxo-2'-deoxyadenosine-5'-Triphosphate; 8-Hydroxy-2'-deoxyadenosine 5'-triphosphoric acid. Grades: ≥ 95% by HPLC. Molecular formula: C10H16N5O13P3 (free acid). Mole weight: 507.18 (free acid). | |
| 8-oxo-dG-CE Phosphoramidite | 8-oxo-dG-CE Phosphoramidite is an indispensable compound assuming a pivotal role in oligonucleotide research and development. Its contributes to the exploration of therapeutic drugs aimed at DNA repair and ailments associated with oxidative stress. Synonyms: 5'-Dimethoxytrityl-N2-isobutyryl-8-oxo-deoxyGuanosine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Grades: 95%. CAS No. 143060-53-1. Molecular formula: C44H54N7O9P. Mole weight: 855.93. | |
| 8-Oxo-dGDP | 8-Oxo-dGDP, a nucleotide analog, serves as a substrate for DNA polymerases and as a regulator for those enzymes associated with DNA repair in biochemical studies. Furthermore, it is employed to explore the involvement of oxidative stress in cancer and neurodegenerative diseases, such as Alzheimer's and Parkinson's. Synonyms: 8-Oxo-2'-deoxyguanosine-5'-diphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H15N5O11P2 (free acid). Mole weight: 443.20 (free acid). | |
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