BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| 8-Oxo-dGMP | 8-Oxo-dGMP is a nucleotide derivative commonly used in research to study DNA damage and repair mechanisms. It is often used to detect and quantify oxidation damage to DNA induced by reactive oxygen species, as well as to investigate the role of 8-oxo-dG in mutagenesis and carcinogenesis. 8-Oxo-dGMP has potential therapeutic applications for the treatment of diseases associated with oxidative stress, such as cancer and neurodegenerative disorders. Synonyms: 8-Oxo-2'-deoxyguanosine-5'-monophosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H14N5O8P (free acid). Mole weight: 363.22 (free acid). |  |
| 8-Oxo-dGP4 | 8-Oxo-dGP4 is a chemical compound used in biomedical research for the study of DNA damage and repair mechanisms. It is a modified form of the nucleoside guanosine and is commonly utilized to identify and quantify oxidative damage to DNA caused by reactive oxygen species. Additionally, 8-Oxo-dGP4 has potential in the development and screening of drugs for the treatment of diseases related to DNA damage, such as cancer and neurodegenerative disorders. Synonyms: 8-Oxo-2'-deoxyguanosine-5'-tetraphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H17N5O17P4 (free acid). Mole weight: 603.16 (free acid). | |
| 8-Oxo-dGTP | 8-Oxo-dGTP can increase the rate of genetic mutation via interfering with the function of nucleic acids. A clastogen is a specific mutagen that causes breaks in chromosomes. Uses: 8-oxo-dgtp is an agent that increase the rate of genetic mutation. Synonyms: 8-Oxo-2'-deoxyguanosine-5'-Triphosphate; 8-Oxodeoxyguanosine triphosphate; 8-Oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate. Grades: ≥95% by AX-HPLC. CAS No. 139307-94-1. Molecular formula: C10H16N5O14P3 (free acid). Mole weight: 523.18 (free acid). | |
| 8-Oxo-GTP | 8-Oxo-GTP, a nucleotide with modifications, is a valuable tool in discovering RNA oxidative and repair mechanisms. Its versatile use also includes investigations into Alzheimer's and Parkinson's, as well as cancer. Its potential to provide antioxidant properties demonstrates promise for defending against oxidative stress in various disease states. Synonyms: 8-Oxoguanosine-5'-Triphosphate. Grades: ≥ 95% by HPLC. CAS No. 21238-36-8. Molecular formula: C10H16N5O15P3 (free acid). Mole weight: 539.18 (free acid). | |
| 8-Oxo-N2-isobutyryl-2'-deoxyguanosine | 8-Oxo-N2-isobutyryl-2'-deoxyguanosine is an exceptional biomedical compound, rendered as a discerning indicator for DNA impairment. It assumes an integral role as a substrate for DNA reparation. Its utilization propels extensive investigation into oxidative species-induced DNA lesions, thereby furnishing profound elucidation into an array of afflictions spanning cancer to neurodegenerative disorders. Synonyms: 8-HYDROXY-N2-ISOBUTRYL-2'-DEOXYGUANOSINE; 8-HYDROXY-N2-ISOBUTRYL-2/'-DEOXYGUANOSINE; N-[9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,8-dioxo-1,7-dihydropurin-2-yl]-2-methylpropanamide; DTXSID40721580; MFCD22373349; N2-Isobutyryl-8-oxo-2'-deoxyguanosine; 2'-Deoxy-N-(2-methylpropanoyl)-8-oxo-7,8-dihydroguanosine; N-(8-hydroxy-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide. Grades: ≥ 90%. CAS No. 136859-76-2. Molecular formula: C14H19N5O6. Mole weight: 353.33. | |
| 8-pCPT-2'-O-Me-5'-AMP | 8-pCPT-2'-O-Me-5'-AMP is a potential metabolite of 8-pCPT-2'-O-Me-cAMP, the specific Epac activator. Synonyms: 8-(4-Chlorophenylthio)-2'-O-methyladenosine-5'-O-monophosphate, sodium salt. Grades: ≥ 97% by HPLC. CAS No. 1187179-94-7. Molecular formula: C17H19ClN5O7PS (free acid). Mole weight: 503.85 (free acid). | |
| 8-pCPT-2'-O-Me-Ado | 8-pCPT-2'-O-Me-Ado is the potential metabolite of 8-pCPT-2'-O-Me-cAMP, a specific Epac activator. Synonyms: 8- (4- Chlorophenylthio)- 2'- O- methyladenosine. Grades: ≥ 98% by HPLC. CAS No. 1187179-96-9. Molecular formula: C17H18ClN6O4S. Mole weight: 423.9. | |
| 8-pCPT-2'-O-Me-cAMP-AM | 8-pCPT-2'-O-Me-cAMP-AM is a precursor of 8-pCPT-2'-O-Me-cAMP, the specific Epac agonist. 8-pCPT-2'-O-Me-cAMP is released after the metabolism of 8-pCPT-2'-O-Me-cAMP-AM by esterases. Synonyms: 8- (4- Chlorophenylthio)- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate, acetoxymethyl ester. Grades: ≥ 97% by HPLC for mixture of isomers. CAS No. 1152197-23-3. Molecular formula: C20H21ClN5O8PS. Mole weight: 557.9. | |
| 8-pCPT-2'-O-Me-cXMP | 8-pCPT-2'-O-Me-cXMP can be used as a control since it has no activated effect on protein kinase G or Epac. Synonyms: 8- (4- Chlorophenylthio)- 2'- O- methylxanthosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. Molecular formula: C17H15ClN4O8PS · Na. Mole weight: 524.8. | |
| 8-pCPT-2'-O-Me-Guo | 8-pCPT-2'-O-Me-Guo is the potential metabolite of the PKG- and Epac-inactive cGMP analogue8-pCPT-2'-O-Me-cGMP. Synonyms: 8- (4- Chlorophenylthio)- 2'- O- methylguanosine. Grades: ≥ 97 % by HPLC. CAS No. 966936-60-6. Molecular formula: C17H18ClN6O6S. Mole weight: 439.9. | |
| 8-pCPT-Ado | 8-pCPT-Ado is the potential metabolite of 8-CPT-cAMP. Synonyms: 8- (4- Chlorophenylthio)adenosine. Grades: ≥ 97 % by HPLC. CAS No. 86362-87-0. Molecular formula: C16H16ClN6O4S. Mole weight: 409.9. | |
| 8-pCPT-Guo | 8-pCPT-Guo, a remarkable agonist with potent effects on the adenosine receptors, specifically targeting adenosine A1R and A3R. Scientific research has found it instrumental in exploring the diverse physiological mechanisms of these receptors. Furthermore, the drug holds immense potential as a treatment option for a range of debilitating conditions such as inflammation, cancer, and neurological disorders. With its multidimensional qualities, 8-pCPT-Guo stands as a compelling player in the medical research landscape. Molecular formula: C16H16ClN6O6S. Mole weight: 426.9. | |
| 8-pCPT-PET-cGMP | 8-pCPT-PET-cGMP is an activator of cyclic GMP-dependent protein kinase as well as an inhibitor of the retinal type cGMP-gated ion channel, thus it can be used for distinction between kinase and ion channel mediated effects. It effects against mammalian cyclic nucleotide-dependent phosphodiesterases. Compared to 8-Br-PET-cGMP, 8-pCPT-PET-cGMP is much more lipophilic and membrane-permeant. Synonyms: 8- (4- Chlorophenylthio)- β- phenyl- 1, N2- ethenoguanosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. Molecular formula: C24H18ClN5O7PS · Na. Mole weight: 609.9. | |
| 8-[φ-450]-cAMP | 8-[φ-450]-cAMP can be used for studies with intact cells for its excellent lipophilicity and bright green fluorescence. Synonyms: 8-[Pharos-450]-adenosine-3',5'-cyclic monophosphate. Grades: ≥ 98% by HPLC. | |
| 8-[φ-450]-cGMP | 8-[φ-450]-cGMP can be used for studies with intact cells for its excellent lipophilicity and bright green fluorescence. Synonyms: 8-[Pharos-450]-guanosine-3',5'-cyclic monophosphate. Grades: ≥ 98% by HPLC. | |
| 8-[φ-575]-2'-O-Me-cAMP | 8-[φ-575]-2'-O-Me-cAMP can be used for studies with intact cells for its excellent lipophilicity and bright red fluorescence. Synonyms: 8-[Pharos-575]-2'-O-methyladenosine-3',5'-cyclic monophosphate. Grades: ≥ 98% by HPLC. Mole weight: 731. | |
| 8-[φ-575]-cAMP | 8-[φ-575]-cAMP can be used for studies with intact cells for its excellent lipophilicity and bright red fluorescence. A tiny hypsochromic shift would be developed while binding to PKA. Synonyms: 8-[Pharos-575]-adenosine-3',5'-cyclic monophosphate. Grades: ≥ 98% by HPLC. | |
| 8-[φ-575]-cGMP | 8-[φ-575]-cGMP is a fuorescent analogue of cGMP, which can be used for studies with intact cells on account of its high lipophilicity and bright red fluorescence. Synonyms: 8-[Pharos-575]-guanosine-3',5'-cyclic monophosphate. Grades: ≥ 98% by HPLC. Mole weight: 500.4. | |
| 8-pMeOPT-Ado | 8-pMeOPT-Ado is a remarkably potent and preferential activator of adenosine receptors, has established itself as an indispensable tool within the realm of biomedical investigation. This exquisite compound serving as an unrivaled agent for deciphering the intricate involvements of adenosine receptors in multifarious pathological states, encompassing cardiac afflictions, inflammatory cascades is as well as neurodegeneration. Synonyms: 8- (4- Methoxyphenylthio)adenosine. Grades: ≥ 97 % by HPLC. CAS No. 696674-66-8. Molecular formula: C17H19N6O6S. Mole weight: 406.4. | |
| 8-PT-Ado | 8-PT-Ado, a nucleoside analog employed for biomedical research, holds promise as an antiviral and anticancer drug. Notably, potency against leukemia and herpes simplex virus has been found. Engaging apoptosis induction, DNA synthesis inhibition, and DNA methyltransferase interference, 8-PT-Ado has also been seen to suppress the NF-κB pathway. This pathway is critical for the progression of inflammation and cancer. Synonyms: 8- Phenylthioadenosine. Grades: ≥ 97 % by HPLC. Molecular formula: C16H17N6O4S. Mole weight: 376.4. | |
| 8-Thioguanosine | 8-Thioguanosine is a significant compound exhibiting remarkable capabilities in studying viral infections and cancer. By proficiently curtailing viral RNA and DNA replication, it effectively subdues the menace of virulence, while concurrently impeding the enhancement of nucleic acids within cancerous cells. Uses: Adjuvants, immunologic. Synonyms: 8-Mercaptoguanosine; 8-SH-Guo; 2-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-8-mercapto-1H-purin-6(9H)-one; 7,8-Dihydro-8-thioxoguanosine; 8-Mercapto-7,8-dihydroguanosin; 8-Tio-Guanosine. Grades: ≥97% by HPLC. CAS No. 26001-38-7. Molecular formula: C10H13N5O5S. Mole weight: 315.31. | |
| 8-Trifluoromethyl-ADP | 8-Trifluoromethyl-ADP is a nucleoside diphosphate that plays a crucial role in energy metabolism. It serves as a substrate for enzymes involved in the synthesis of ATP, which is a key currency of cellular energy. Additionally, it is also used in research to study the regulation of various ion channels and transporters, as well as to investigate signal transduction pathways implicated in a variety of diseases such as cancer and neurological disorders. Synonyms: 8-Trifluoromethyl-adenosine-5'-diphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C11H14N5O10P2F3 (free acid). Mole weight: 495.20 (free acid). | |
| 9-(2',3',5'-Tri-O-benzyl-b-D-arabinofuranosyl)adenine | 9-(2',3',5'-Tri-O-benzyl-b-D-arabinofuranosyl)adenine, commonly known as TBA, is an immensely powerful antiviral compound that displays inhibitory efficacy in research of a wide array of malignancies such as leukemia, lymphoma and solid tumors. By obstructing the propagation of viral DNA and RNA, this pharmacological compound successfully impedes the proliferation and dissemination of malignant cells. Synonyms: 9-(2',3',5'-Tri-O-benzyl-b-D-arabinofuranosyl) adenine. CAS No. 3257-73-6. Molecular formula: C31H31N5O4. Mole weight: 537.61. | |
| 9-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-2,6-diaminopurine (FANA-DAP) | FANA-DAP, a nucleotide analogue, exhibits the capability to target selective immune cells; cytotoxic T lymphocytes and natural killer cells, and is effective in enhancing their activity against tumor cells. This unique immunomodulatory drug shows great potential as a therapeutic agent in combating various types of cancer, including melanoma, prostate cancer, and hepatocellular carcinoma. The complex structure and mechanism of FANA-DAP make it a potential candidate for advancing cancer treatment and is a promising area of research for future studies. Grades: ≥ 97%. Molecular formula: C10H15FN6O3. Mole weight: 286.2629. | |
| 9-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-6-thioguanine (FANA-thioG) | 9-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-6-thioguanine (FANA-thioG) is a remarkable and cutting-edge compound, exhibiting its profound impact in research of both antiviral and anticancer domains. By impeding the process of DNA enhancement, FANA-thioG effectively curbs the propagation of malignant cells and the replication of viruses. Grades: ≥ 97%. Molecular formula: C10H12FN5O3S. Mole weight: 301.2974. | |
| 9-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)adenine (2-FANA-A) | | |
| 9-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)guanine (2-FANA-G) | | |
| 9-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)hypoxantine (2-FANA-I) | | |
| 9-(2'-O-Acetyl-3',5'-di-O-benzoyl-3'-beta-C-methyl-beta-D-ribofuranosyl)-6-chloropurine | 9-(2'-O-Acetyl-3',5'-di-O-benzoyl-3'-beta-C-methyl-beta-D-ribofuranosyl)-6-chloropurine, a remarkable antiviral compound, exhibits exceptional potency against diverse viral infections. Its distinctive molecular composition facilitates precise targeting and subsequent inhibition of viral DNA or RNA replication. Consequently, vital viral replication mechanisms are impeded, resulting in the effective suppression of viral proliferation. Grades: ≥95%. Molecular formula: C27H23ClN4O7. Mole weight: 550.95. | |
| 9-(2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-beta-D-ribofuranosyl)-6-chloropurine | 9-(2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-beta-D-ribofuranosyl)-6-chloropurine is a formidable antiviral compound, exhibiting exceptional capabilities in research of various viral infections. Its mode of action involves repressing viral replication, DNA enhancement and viral nucleic acid enhancement. Synonyms: 9-(2-O-Acetyl-5-O-benzoyl-3-deoxy-β-D-erythro-pentofuranosyl)-6-chloro-9H-purine; ((2S,4R,5R)-4-Acetoxy-5-(6-chloro-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl benzoate; (5S,2R,3R)-2-(6-chloropurin-9-yl)-5-(phenylcarbonyloxymethyl)oxolan-3-yl acetate. Grades: ≥95%. CAS No. 1347118-41-5. Molecular formula: C19H17ClN4O5. Mole weight: 416.82. | |
| 9-(2'-O-Acetyl-5'-O-benzoyl-3'-O-methyl-beta-D-ribofuranosyl)-2,6-dichloropurine | 9-(2'-O-Acetyl-5'-O-benzoyl-3'-O-methyl-beta-D-ribofuranosyl)-2,6-dichloropurine, a remarkably powerful antiviral agent widely employed in the biomedical field, showcases its profound efficacy against a myriad of viral afflictions such as influenza, herpes, and hepatitis. Grades: ≥95%. CAS No. 2072145-40-3. Molecular formula: C20H18Cl2N4O6. Mole weight: 481.29. | |
| 9-(2'-O-Acetyl-5'-O-benzoyl-3'-O-methyl-beta-D-ribofuranosyl)-6-chloropurine | 9-(2'-O-Acetyl-5'-O-benzoyl-3'-O-methyl-beta-D-ribofuranosyl)-6-chloropurine, a highly intricate and multifaceted compound, occupies a pivotal role in the realm of biomedical science due to its profound pharmacological implications. Esteemed for its unrivaled prowess, this compound finds immense utility in combating an array of ailments, notably a diverse range of cancers. Grades: ≥95%. CAS No. 2072145-46-9. Molecular formula: C20H19ClN4O6. Mole weight: 446.84. | |
| 9-(2-O-Acetyl-5-O-(p-toluoyl)-3-deoxy-3-fluoro-beta-D-ribofuranosyl)-2-amino-6-chloro-9H-purine | 9-(2-O-Acetyl-5-O-(p-toluoyl)-3-deoxy-3-fluoro-beta-D-ribofuranosyl)-2-amino-6-chloro-9H-purine is a robust antiviral compound, exhibiting inhibitory efficacy in research of a wide array of viral infections, notably hepatitis B and C. By selectively antagonizing pivotal enzymes implicated in viral nucleotide research and development, this compound powerfully inhibits viral DNA replication. Synonyms: 9-[2-O-Acetyl-3-deoxy-3-fluoro-5-O-(4-methylbenzoyl)-β-D-ribofuranosyl]-6-chloro-9H-purin-2-amine; ((2R,3R,4S,5R)-4-Acetoxy-5-(2-amino-6-chloro-9H-purin-9-yl)-3-fluorotetrahydrofuran-2-yl)methyl 4-methylbenzoate; 9-(2-O-Acetyl-5-O-toluyl-3-deoxy-3-fluoro-beta-D-ribofuranosyl)-2-amino-6-chloro-9H-purine. Grades: ≥95%. CAS No. 1612192-25-2. Molecular formula: C20H19ClFN5O5. Mole weight: 463.85. | |
| 9-(2-O-Acetyl-5-O-(p-Toluoyl)-3-deoxy-3-fluoro-beta-D-ribofuranosyl)-6-chloro-9H-purine | 9-(2-O-Acetyl-5-O-(p-Toluoyl)-3-deoxy-3-fluoro-beta-D-ribofuranosyl)-6-chloro-9H-purine, a highly complex compound, exhibits remarkable efficacy as an antiviral agent within the biomedical sector. Synonyms: 5'-O-(p-Toluoyl)-2'-O-acetyl-3'-deoxy-3'-fluoro-6-chloroinosine; 2'-O-Acetyl-2-chloro-3'-deoxy-3'-fluoro-5'-O-toluoylinosine; ((2R,3R,4S,5R)-4-Acetoxy-5-(6-chloro-9H-purin-9-yl)-3-fluorotetrahydrofuran-2-yl)methyl 4-methylbenzoate; 9-(2-O-Acetyl-5-O-toluyl-3-deoxy-3-fluoro-beta-D-ribofuranosyl)-6-chloro-9H-purine; 9-[2-O-Acetyl-3-deoxy-3-fluoro-5-O-(4-methylbenzoyl)-β-D-ribofuranosyl]-6-chloro-9H-purine. Grades: ≥95%. CAS No. 1612192-06-9. Molecular formula: C20H18ClN4O5. Mole weight: 448.83. | |
| 9-[3-Deoxy-3-C-fluoro-β-D-ribofuranosyl]guanine | It is an antiviral agent. Synonyms: 3'-Deoxy-3'-fluoroguanosine; 2-Amino-9-((2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 3'-fluoro-3'-deoxyguanosine; 2-Amino-9-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)-9H-purin-6-ol. Grades: ≥95%. CAS No. 123402-21-1. Molecular formula: C10H12FN5O4. Mole weight: 285.23. | |
| 9-(3'-Deoxy-3'-fluoro-b-D-ribofuranosyl)-6-(thiophen-3-yl)purine | 9-(3'-Deoxy-3'-fluoro-b-D-ribofuranosyl)-6-(thiophen-3-yl)purine, a purine analog, has been established as an efficacious medication for cancer treatment, notably for leukemia and lymphoma. It inhibits DNA synthesis, thereby promoting cell death specifically in cancer cells. Moreover, combination with other chemotherapy agents has been demonstrated to enhance therapeutic effects. Extensive studies have validated its effectiveness, affording healthcare providers an option for treating cancer. Synonyms: 6-(Thiophen-3-yl)purine-beta-D-(3'-deoxy-3'-fluoro)riboside; 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(thiophen-3-yl)purine; (2R,3S,4S,5R)-4-fluoro-5-(hydroxymethyl)-2-(6-thiophen-3-ylpurin-9-yl)oxolan-3-ol; 9H-Purine, 9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)-6-(3-thienyl)-. Grades: ≥95%. CAS No. 1612191-90-8. Molecular formula: C14H13FN4O3S. Mole weight: 336.34. | |
| 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-2-chloro-6-(thiophen-3-yl)purine | 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-2-chloro-6-(thiophen-3-yl)purine is a formidable antiviral compound, extensively employed in studying select viral afflictions. Synonyms: 2-Chloro-6-(thiophen-3-yl)purine-beta-D-(3'-deoxy-3'-fluoro)riboside; 2-Chloro-9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)-6-(3-thienyl)-9H-purine; (2R,3S,4S,5R)-2-(2-chloro-6-thiophen-3-ylpurin-9-yl)-4-fluoro-5-(hydroxymethyl)oxolan-3-ol. Grades: ≥95%. CAS No. 1612192-01-4. Molecular formula: C14H12ClFN4O3S. Mole weight: 370.79. | |
| 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(5-phenylpyridin-3-yl)purine | 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(5-phenylpyridin-3-yl)purine, an exquisite compound widely employed in the biomedical field, exhibits remarkable potential as a selective and robust inhibitor against a spectrum of viral infections. By expertly targeting the viral polymerases, this inhibitor efficacy halts virus replication by meticulously impeding viral RNA synthesis. Consequently, it presents a highly promising avenue for combatting RNA virus-induced afflictions. Synonyms: (2R,3S,4S,5R)-4-fluoro-5-(hydroxymethyl)-2-[6-(5-phenylpyridin-3-yl)purin-9-yl]oxolan-3-ol. Grades: ≥95%. CAS No. 1612191-96-4. Molecular formula: C21H18FN5O3. Mole weight: 407.40. | |
| 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[5-(propyn-1-yl)pyridin-3-yl]purine | 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[5-(propyn-1-yl)pyridin-3-yl]purine, a noteworthy antiviral compound extensively employed in the biomedical sector, possesses the ability to combat diverse viral infections. It demonstrates exceptional potency against select viral strains by hindered replication and diffusion. The distinct molecular arrangement of this substance facilitates precise and focused interplay with viral enzymes, establishing its indispensable status as a therapeutic intervention in the war against viral pathogens. Synonyms: 9H-Purine, 9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)-6-[5-(1-propyn-1-yl)-3-pyridinyl]-; (2R,3S,4S,5R)-4-fluoro-5-(hydroxymethyl)-2-[6-(5-prop-1-ynylpyridin-3-yl)purin-9-yl]oxolan-3-ol. Grades: ≥95%. CAS No. 1612191-95-3. Molecular formula: C18H16FN5O3. Mole weight: 369.35. | |
| 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[6-(4-morpholinyl)pyridin-3-yl]purine | 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[6-(4-morpholinyl)pyridin-3-yl]purine, a remarkable antiviral agent extensively employed in the realm of biomedicine, showcases its efficacy in combating a wide array of viral infections encompassing hepatitis B and C, HIV, and herpes. By selectively impeding viral replication through intricate interactions with viral enzymes, this product stands out for its exceptional mechanism of action, offering compelling prospects for therapeutic interventions targeting viral diseases of diverse origins. Synonyms: 9H-Purine, 9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)-6-[6-(4-morpholinyl)-3-pyridinyl]-; (2R,3S,4S,5R)-4-fluoro-5-(hydroxymethyl)-2-[6-(6-morpholin-4-ylpyridin-3-yl)purin-9-yl]oxolan-3-ol. Grades: ≥95%. CAS No. 1612191-98-6. Molecular formula: C19H21FN6O4. Mole weight: 416.41. | |
| 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-methyl-9H-purine | 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-methyl-9H-purine is an exceptionally efficacious antiviral compound, indispensably employed in studying multifarious RNA viral infections such as influenza, hepatitis C and the pernicious human immunodeficiency virus (HIV). Executing its mechanism by impeding viral replication, it unequivocally diminishes viral burden. Synonyms: 6-Methylpurine-beta-D-(3-deoxy-3-fluoro)riboside; (2R,3S,4S,5R)-4-Fluoro-5-(hydroxymethyl)-2-(6-methyl-9H-purin-9-yl)tetrahydrofuran-3-ol. Grades: ≥95%. CAS No. 1612191-88-4. Molecular formula: C11H13FN4O3. Mole weight: 268.24. | |
| 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(naphthalen-1-yl)purine | 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(naphthalen-1-yl)purine is an exquisite antiviral compound harnessed for studying the treacherous menace of viral infections. Renowned for its ability to perturb viral nucleic acid enhancement and impede viral polymerases, this exceptional compound undeniably stifles viral replication. Synonyms: 9H-Purine, 9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)-6-(1-naphthalenyl)-; (2R,3S,4S,5R)-4-fluoro-5-(hydroxymethyl)-2-(6-naphthalen-1-ylpurin-9-yl)oxolan-3-ol. Grades: ≥95%. CAS No. 1612191-92-0. Molecular formula: C20H17FN4O3. Mole weight: 380.37. | |
| 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-phenylpurine | 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-phenylpurine, known for its potent antiviral properties, showcases remarkable efficacy in combating selected viral infections. By selectively inhibiting key enzymes crucial for viral RNA synthesis, this therapeutic agent effectively hampers viral replication. Groundbreaking results have been observed in the management of RNA virus-induced ailments like hepatitis C and influenza. Synonyms: 9H-Purine, 9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)-6-phenyl-; (2R,3S,4S,5R)-4-fluoro-5-(hydroxymethyl)-2-(6-phenylpurin-9-yl)oxolan-3-ol. Grades: ≥95%. CAS No. 1612191-91-9. Molecular formula: C16H15FN4O3. Mole weight: 330.31. | |
| 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(pyridine-4-yl)purine | 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(pyridine-4-yl)purine is a potent antiviral compound used in the research of viral infections, including certain strains of influenza and herpes viruses. It acts by inhibiting viral replication, thus reducing the severity and duration of the infection. Extensive research has shown promising results in its therapeutic efficacy against a range of viral diseases. Synonyms: 9H-Purine, 9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)-6-(4-pyridinyl)-; (2R,3S,4S,5R)-4-fluoro-5-(hydroxymethyl)-2-(6-pyridin-4-ylpurin-9-yl)oxolan-3-ol. Grades: ≥95%. CAS No. 1612191-93-1. Molecular formula: C15H14FN5O3. Mole weight: 331.30. | |
| 9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)purine | 9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)purine is an exceptionally potent biomedical agent extensively employed to combat viral infections. With remarkable precision, it aims at impeding viral replication and dissemination. This compound exhibits immense promise in the therapeutic management of a diverse array of viral afflictions, encompassing respiratory infections, herpes, and multiple forms of viral hepatitis. Mechanistically, it exerts its effects by obstructing crucial viral enzymes indispensable for the synthesis of viral DNA/RNA, thereby impeding their capacity to proliferate and induce further harm to the host organism. Synonyms: (2R,3S,4S,5R)-4-fluoro-5-(hydroxymethyl)-2-(9H-purin-9-yl)tetrahydrofuran-3-ol; 3-Fluoronebularine; 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-9H-Purine. Grades: ≥95%. CAS No. 124775-29-7. Molecular formula: C10H11FN4O3. Mole weight: 254.22. | |
| 9-(5'-O-Benzoyl-N4-benzoyl-2-deoxy-beta-D-threo-pentofuranosyl)adenine | 9-(5'-O-Benzoyl-N4-benzoyl-2-deoxy-beta-D-threo-pentofuranosyl)adenine, a highly potent antiviral agent utilized extensively in the biomedical sector, showcases its prowess in curbing viral infections. Its mode of action entails the suppression of viral DNA synthesis, rendering it efficacious against an array of viral ailments, such as HIV, hepatitis B, and herpes. Synonyms: [(2R,3R,5R)-5-(6-benzamidopurin-9-yl)-3-hydroxyoxolan-2-yl]methyl benzoate; N6-Benzoyl-9-(5-O-benzoyl-2-deoxy-beta-D-threo-pentofuranosyl)adenine; Benzamide, N-[9-(5-O-benzoyl-2-deoxy-β-D-threo-pentofuranosyl)-9H-purin-6-yl]-. Grades: ≥95%. Molecular formula: C24H21N5O5. Mole weight: 459.45. | |
| 9-(5(R)-C-Methyl-2,3,5-tri-O-benzoyl-b-D-ribofuranosyl)-6-chloropurine | 9-(5(R)-C-Methyl-2,3,5-tri-O-benzoyl-b-D-ribofuranosyl)-6-chloropurine, a remarkably robust antiviral compound, finds extensive application in combating viral infections, especially those triggered by DNA viruses. Its exquisite specificity enables it to effectively combat various strains of viruses such as herpes simplex virus types 1 and 2, varicella-zoster virus, as well as Epstein-Barr virus. Synonyms: [(2R,3R,4R,5R)-4-benzoyloxy-2-[(1R)-1-benzoyloxyethyl]-5-(6-chloropurin-9-yl)oxolan-3-yl] benzoate. Grades: ≥95%. Molecular formula: C32H25ClN4O7. Mole weight: 613.02. | |
| 9-(b-D-Xylofuranosyl)adenine | It is an anticancer agent. Synonyms: 9-beta-D-Xylofuranosyladenine; NSC 7359; 9-beta-D-Xylofuranosyl-9H-purine-6-amine; (2R,3R,4R,5R)-2-(6-Amino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; Adenine xyloside; Xylosyladenine; Xylosyl A. Grades: ≥95%. CAS No. 524-69-6. Molecular formula: C10H13N5O4. Mole weight: 267.24. | |
| 9-(b-D-Xylofuranosyl)guanine | 9-(β-D-Xylofuranosyl)guanine, a renowned biomedicine product, is widely recognized for its efficaciousness in combating viral infections, particularly those induced by herpes viruses. Functioning as an antiviral agent, this compound effectively hinders the proliferation of viral DNA, thereby mitigating viral burden and alleviating symptoms related to herpes virus infections. Synonyms: 6H-Purin-6-one, 1,9-dihydro-2-amino-9-beta-D-xylofuranosyl-; 2-Amino-9-(β-D-xylofuranosyl)-1,9-dihydro-6H-purin-6-one; 2-Amino-9-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one. Grades: ≥95%. CAS No. 27462-39-1. Molecular formula: C10H13N5O5. Mole weight: 283.24. | |
| 9-Deaza-2'-deoxyguanosine | 9-Deaza-2'-deoxyguanosine is a renowned compound in the biomedical sector, exhibiting profound versatility as a potent antiviral and antitumor compound. By virtue of its remarkable attributes, this compound showcases an exceptional potential for studying the detrimental consequences of viral infections and malignant neoplasms. Synonyms: 9-Deaza-2'-deoxyguanosine(2-amino-7-(beta-d-2-deoxyribofuranosyl)pyrrolo[3,2-d]pyrimidin-4-one). Grades: ≥ 97%. CAS No. 224946-77-4. Molecular formula: C11H14N4O4. Mole weight: 266.26. | |
| 9-Deazaguanosine | 9-Deazaguanosine is an antiviral compound, impeding viral replication and invigorating immune responses. Grades: ≥ 97%. CAS No. 102731-45-3. Molecular formula: C11H14N4O5. Mole weight: 282.26. | |
| 9-Ethylguanine | 9-Ethylguanine, a chemical compound utilized by the biomedical industry to probe the mechanisms of DNA repair, may also serve as a biomarker for carcinogenic effects caused by substances like tobacco smoke. Studies have indicated its potential involvement in the pathogenesis of bladder cancer and other malignancies. Synonyms: 2-Amino-9-ethyl-1,9-dihydro-6H-purin-6-one; NSC 22755; 2-amino-9-ethyl-1H-purin-6(9H)-one; 2-amino-9-ethyl-3H-purin-6-one; 2-Amino-9-ethyl-6-hydroxypurine; 6-Amino-9-ethyl-2-hydroxypurine; NSC 22755. Grades: ≥98% by HPLC. CAS No. 879-08-3. Molecular formula: C7H9N5O. Mole weight: 179.18. | |
| 9-Methyladenine | A receptor adenine derivative binding membrane brain animal cell line. Synonyms: N9-Methyladenine; 6-Amino-9-methylpurine; 9-Methyl Adenine; 9-Methyl-9H-purin-6-amine; NSC 7843; 9-Methyl-9H-adenine; 9-methyl-9H-purin-6-ylamine. Grades: ≥95% by HPLC. CAS No. 700-00-5. Molecular formula: C6H7N5. Mole weight: 149.15. | |
| 9-Ribofuranosyl-9H-Purine-6-thiol | 9-Ribofuranosyl-9H-Purine-6-thiol, utilized as an antiviral therapy to hinder viral replication, has been demonstrated to treat viral infections including, but not limited to, Hepatitis B and HIV. Its selectivity enables the targeted impact on infected CD4 T-helper cells, subsequently leading to a decrease of the viral load while simultaneously heightening the CD4 cell count. Synonyms: 9H-Purine-6-thiol, 9-ribofuranosyl-; 6H-Purine-6-thione, 3,9-dihydro-9-D-ribofuranosyl-; 6-Mercapto-9β-D-ribofuranosyl-9H-purine; 9-(D-Ribofuranosyl)-3,9-dihydro-6H-purine-6-thione; 9-(D-ribofuranosyl)-9H-purine-6-thiol. Grades: ≥97% by HPLC. CAS No. 4988-64-1. Molecular formula: C10H12N4O4S. Mole weight: 284.29. | |
| A 1070722 | A 1070722 is a potent glycogen synthase kinase-3 (GSK-3) inhibitor (Ki = 0.6 nM for GSK-3α and GSK-3β) with 50-fold selectivity over other protein kinases such as CDK. It decreases phosphorylation of microtubule-associated protein Tau in vitro. A 1070722 exhibits neuroprotective activity thus is identified as a therapeutic drug candidate for neurodegenerative and psychiatric disorders. Uses: Potential treatment of neurodegenerative disorders. Synonyms: A 1070722; A1070722; A-1070722; 1-(7-Methoxyquinolin-4-yl)-3-[6-(trifluoromethyl)pyridin-2-yl]urea. Grades: ≥99% by HPLC. CAS No. 1384424-80-9. Molecular formula: C17H13F3N4O2. Mole weight: 362.31. | |
| A-1165442 | A-1165442 is a potent, competitive and orally available modality-differentiated second-generation TRPV1 antagonist with good analgesic efficacy and a temperature-neutral profile (IC50 = 9 nM for human TRPV1). Synonyms: A1165442; A 1165442; A-1165442; 1-[(4R)-7-chloro-2,2-bis(fluoromethyl)-3,4-dihydrochromen-4-yl]-3-(3-methylisoquinolin-5-yl)urea; 1-(7-chloro-2,2-bis(fluoromethyl)chroman-4-yl)-3-(3-methylisoquinolin-5-yl)urea. CAS No. 1221443-94-2. Molecular formula: C22H20ClF2N3O2. Mole weight: 431.86. | |
| A1874 | A1874 is a nutlin-based and BRD4-degrading PROTAC which induces BRD4 degradation in cells. A1874 (A-1874) is a nutlin-based and BRD4-degrading PROTAC with DC50 of 32 nM (induce BRD4 degradation in cells); A1874 is more effective in inhibiting proliferation of many cancer cell lines with wild type p53 than was a corresponding VHL-utilizing PROTAC with similar potency and efficacy to degrade BRD4; demonstrates synergistic antiproliferative effect via simultaneous degradation of BRD4 and stabilization of p53. Synonyms: A1874; A 1874; A-1874; (2R,3S,4R,5S)-3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-N-(4-((1-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-2-oxo-6,9,12-trioxa-3-azatetradecan-14-yl)carbamoyl)-2-methoxyphenyl)-4-cyano-5-neopentylpyrrolidine-2-carboxamide. CAS No. 2064292-12-0. Molecular formula: C58H62Cl3F2N9O7S. Mole weight: 1173.59. | |
| A-205804 | A-205804 is a potent, selective and orally bioavailable lead inhibitor of E-selectin and ICAM-1 expression, with IC50s of 20 and 25 nM for E-selectin and ICAM-1, respectively. It can be used in the study of chronic inflammatory diseases. Synonyms: 4-(p-Tolylthio)thieno[2,3-c]pyridine-2-carboxamide; 4-[(4-methylphenyl)thio]thieno[2,3-c]pyridine-2-carboxamide; 4-(p-Tolylsulfanyl)thieno[2,3-c]pyridine-2-carboxamide. Grades: >98%. CAS No. 251992-66-2. Molecular formula: C15H12N2OS2. Mole weight: 300.40. | |
| A2AR antagonist 1 | A2AR antagonist 1 is a potent A2AR (Adenosine A2A Receptor) antagonist with Ki values of 4 nM and 264 nM for A2AR and A1R, respectively. Synonyms: 1-[(2-fluorophenyl)methyl]-4-(furan-2-yl)pyrazolo[3,4-d]pyrimidin-6-amine. Grades: ≥95%. CAS No. 443103-97-7. Molecular formula: C16H12FN5O. Mole weight: 309.30. | |
| A2-Iso5-2DC18 | A2-Iso5-2DC18 is a top-performing lipid for mRNA delivery in bone marrow-derived dendritic cells (BMDCs), BMDMs and HeLa cells. Synonyms: ethyl 5,5-di((z)-heptadec-8-en-1-yl)-1-(3-(pyrrolidin-1-yl)propyl)-2,5-dihydro-1h-imidazole-2-carboxylate. Molecular formula: C47H87N3O2. Mole weight: 726.21. | |
| A-317491 | A-317491 is a potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors stimulate the pronociceptive effects of ATP upon activation. Uses: P2x3 and p2x2/3 receptor antagonist. Synonyms: ABT 202; A-317491 sodium; ABT202; A317491 sodium; ABT-202; A 317491 sodium; 5-[(3-phenoxyphenyl)methyl-[(1S)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]benzene-1,2,4-tricarboxylic acid. Grades: ≥95%. CAS No. 475205-49-3. Molecular formula: C33H27NO8. Mole weight: 565.57. | |
| A 331440 dihydrochloride | A 331440 dihydrochloride is a histamine H3 receptor antagonist (Ki = 21.7 and 22.7 nM for rat and human H3 receptors, respectively). A 331440 reduces weight in a diet-induced obesity model. Synonyms: A-331440 dihydrochloride; A 331440 dihydrochloride; A331440 dihydrochloride; 4'-[3-[(3R)-3-(Dimethylamino)-1-pyrrolidinyl]propoxy]-[1,1'-biphenyl]-4-carbonitrile dihydrochloride. Grades: ≥98% by HPLC. CAS No. 1049740-32-0. Molecular formula: C22H27N3O.2HCl. Mole weight: 422.39. | |
| A-366833 | A-366833 is a an agonist at neural nicotinic acetylcholine receptors selective for the α4β2 subtype. Uses: Neural nicotinic acetylcholine receptors selective for the α4β2 subtype. Synonyms: A-366833; A 366833; A366833; 5-[(1R,5S)-3,6-diazabicyclo[3.2.0]heptan-6-yl]pyridine-3-carbonitrile. Grades: ≥98%. CAS No. 370882-41-0. Molecular formula: C11H12N4. Mole weight: 200.24. | |
| A37 | A37 is an aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitor (IC50 = 4.6 μM; Ki = 300 nM). It competitively binds to the aldehyde binding pocket of ALDH1A1, resulting in the disruption of spheroid formation and a decrease of cell viability in ovarian cancer cells in vitro. Synonyms: Ethyl 2-[[3, 4-dihydro-4-oxo-3-[3- (1-pyrrolidinyl) propyl][1]benzothieno[3, 2-d]pyrimidin-2-yl]thio]acetate; CM037; CM-037; CM 037; A37; A-37; A 37. Grades: ≥97% by HPLC. CAS No. 896795-60-1. Molecular formula: C21H25N3O3S2. Mole weight: 431.57. | |
| A-381393 | A-381393 is a potent and selective dopamine D4 receptor agonist. Synonyms: A 381393; CHEMBL127257. Grades: 98%. CAS No. 726174-00-1. Molecular formula: 20H24N4. Mole weight: 320.4. | |
| A 410099.1 amide-PEG2-amine-Boc | A 410099.1 amide-PEG2-amine-Boc is a functionalized IAP ligand containing an IAP ligand and a PEG linker of 2 O(CH2)2 units with Boc protected terminal amine, can be used to bind to the target protein ligand. CAS No. 2415256-16-3. Molecular formula: C38H60N6O8. Mole weight: 728.92. | |
| A 410099.1 amide-PEG3-amine-Boc | A 410099.1 amide-PEG3-amine-Boc is a functionalized IAP ligand containing an IAP ligand and a PEG linker of 3 O(CH2)2 units with Boc protected terminal amine, can be used to bind to the target protein ligand. CAS No. 2415256-19-6. Molecular formula: C40H64N6O9. Mole weight: 772.97. | |
| A 410099.1, amine-Boc hydrochloride | A 410099.1, amine-Boc hydrochloride is an IAP ligand that can be used in the synthesis of PROTAC, whose Boc protected terminal amine support to bind a target protein ligand. CAS No. 2374122-37-7. Molecular formula: C32H50ClN5O5. Mole weight: 620.22. | |
| A 412997 dihydrochloride | A 412997 dihydrochloride is a potent and selective agonist for the dopamine D4 receptor (Ki = 7.9 and 12.1 nM for human D4 and rat D4, receptors) with no activity for other dopamine receptors. Synonyms: A-412997 dihydrochloride; A412997 dihydrochloride; A-412997 dihydrochloride; N-(3-Methylphenyl)-4-(2-pyridinyl)-1-piperidineacetamide. Grades: ≥98% by HPLC. CAS No. 1347744-96-0. Molecular formula: C19H23N3O.2HCl. Mole weight: 382.33. | |
| A 419259 | A-419259 is a potent inhibitor of Src family kinases. IC50 values for src, lck, blk, csk, fyn and lyn range between 15 and 50 nM. Synonyms: A419259; A-419259; RK 20449; RK20449; RK-20449. Grades: >98%. CAS No. 364042-47-7. Molecular formula: C29H34N6O. Mole weight: 482.62. | |
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