BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Ac-LETD-AFC | Ac-LETD-AFC is a fluorogenic substrate for caspase-8. Caspase activity can be quantified by fluorescent detection of free AFC (7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm. Synonyms: N-Acetyl-Leu-Glu-Thr-Asp-7-amino-4-Trifluoromethylcoumarin; N-acetyl-L-leucyl-L-α-glutamyl-L-threonyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine. Grades: ≥95%. CAS No. 210345-02-1. Molecular formula: C31H38F3N5O12. Mole weight: 729.7. |  |
| Ac-LEVD-CHO trifluoroacetate salt | Ac-LEVD-CHO is a caspase-4 inhibitor. It inhibits IL-1α expression and secretion and caspase-4 activation induced by the T. denticola periodontal pathogen surface protein Td92 in human gingival fibroblasts when used at a concentration of 30 μM. Synonyms: Ac-Leu-Glu-Val-Asp-CHO; Caspase-4 Inhibitor I. Grades: ≥95%. CAS No. 402832-01-3. Molecular formula: C22H36N4O9·xCF3COOH. Mole weight: 500.5. | |
| Aclidinium Bromide | Aclidinium Bromide(LAS 34273; LAS-W 330) is a long-acting, inhaled muscarinic antagonist as a maintenance treatment for chronic obstructive pulmonary disease (COPD). Synonyms: trade name: Eklira Genuair; Tudorza Genuair; Bretaris Genuair. Grades: 0.98. CAS No. 320345-99-1. Molecular formula: C26H30BrNO4S2. Mole weight: 564.553. | |
| Ac-Linaclotide | Ac-Linaclotide is an impurity of Linaclotide, which is a peptide agonist of guanylate cyclase 2C used for the treatment of abdominal pain in patients with irritable bowel syndrome (IBS) associated with constipation. Synonyms: Ac-L-cysteinyl-L-cysteinyl-L-alpha-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-aspargenyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonyl-glycyl-L-cysteinyl-L-tyrosine (1-6),(2-10),(5-13)-tris(disulfide); Ac-Cys-Cys-Glu-Tyr-Cys-Cys-Asn-Pro-Ala-Cys-Thr-Gly-Cys-Tyr-OH (disulfide bridges between 1-6, 2-10 and 5-13 Cysteines); N-Acetyl-linaclotide; L-Tyrosine, N-acetyl-L-cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-, cyclic (1?6),(2?10),(5?13)-tris(disulfide). CAS No. 1422389-17-0. Molecular formula: C61H81N15O22S6. Mole weight: 1568.76. | |
| Ac-Lys-AMC | Ac-Lys-AMC, also known as MAL, is a fluorescent substrate for histone deacetylases (HDACs). Synonyms: (S)-2-Acetamido-6-amino-N-(4-methyl-2-oxo-2H-chromen-7-yl)hexanamide; N2-Acetyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-lysinamide; Hexanamide, 2-(acetylamino)-6-amino-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-, (2S)-. Grades: ≥98%. CAS No. 156661-42-6. Molecular formula: C18H23N3O4. Mole weight: 345.40. | |
| Ac-Lys-D-Ala-D-lactic acid acetate | Grades: >99%. CAS No. 282729-62-8. Molecular formula: C16H29N3O8. Mole weight: 391.42. | |
| Ac-Lys-Gln-Leu-Arg-AFC | Ac-Lys-Gln-Leu-Arg-AFC is the optimal substrate for human Hepsin, because KQLR/VVNG corresponds to its cleavage site. Excitation at 395-400 nm, emission at 495-505 nm. Hepsin is a membrane-anchored serine protease that is overexpressed in ovarian, prostate cancer and renal cell carcinomas, and therefore can be used as a prognostic marker. Synonyms: Ac-KQLR-AFC; L-Argininamide, N2-acetyl-L-lysyl-L-glutaminyl-L-leucyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-; N2-Acetyl-L-lysyl-L-glutaminyl-L-leucyl-N-[2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl]-L-argininamide. Grades: ≥95%. CAS No. 1802078-38-1. Molecular formula: C35H51F3N10O8. Mole weight: 796.84. | |
| Acmella Oleracea Extract | Acmella Oleracea extract, a potent natural alternative to Botox, can be used in medical treatments and has anti-aging effects. The extract features analgesic alkylamides called Spilanthol. It has been used to treat skin diseases such as ringworm, athletes' foot, and nail infections. | |
| Ac-Nle-Pro-Nle-Asp-AMC | Ac-Nle-Pro-Nle-Asp-AMC is a substrate for proteasomes. It can be cleaved by the caspase-like site of proteasome, also known as postglutamyl peptide hydrolase (PGPH). AMC (7-amino-4-methylcoumarin) is released and produces the fluorescence utilized to quantify the caspase-like site activity. Ac-Nle-Pro-Nle-Asp-AMC also inhibits the chymotrypsin-like activity of the proteasome allosterically when bound to the caspase-like site. Synonyms: Ac-Nle-Pro-Nle-Asp-7-amido-4-Methylcoumarin; Ac-nLPnLD-AMC; N-acetyl-L-norleucyl-L-prolyl-L-norleucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-α-asparagine; L-α-Asparagine, N-acetyl-L-norleucyl-L-prolyl-L-norleucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-; (3S) -4-Hydroxy-3- ({ (2S) -1-hydroxy-2-[ (hydroxy{ (2S) -1-[N- (1-hydroxyethylidene) -L-norleucyl]-2-pyrrolidinyl}methylene) amino]hexylidene}amino) -4-[ (4-methyl-2-oxo-2H-chromen-7-yl) imino]butanoic acid. Grades: ≥98%. CAS No. 355140-49-7. Molecular formula: C33H45N5O9. Mole weight: 655.74. | |
| Ac-Octreotide | Ac-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: Ac-D-phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); N-Acetyl-Phe-Octreotide; L-Cysteinamide, N-acetyl-D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2?7)-disulfide; L-Cysteinamide, N-acetyl-D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2?7)-disulfide, [R-(R*,R*)]-; N-Acetyl-D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamide cyclic (2?7)-disulfide; D-Phe(Ac)-Octreotide; Ac-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-ol (Disulfide bridge: Cys2-Cys7). Grades: ≥95%. CAS No. 83795-61-3. Molecular formula: C51H68N10O11S2. Mole weight: 1061.28. | |
| Acolbifene | Acolbifene, also known as EM-652, or SCH-57068, is a selective estrogen receptor modulator (SERM). Acolbifene is currently being studied in the prevention of breast cancer in women at high risk of breast cancer. EM-652 is the compound having the highest affinity for the estrogen receptor, including estradiol. It has higher affinity for the ER than ICI 182780, hydroxytamoxifen, raloxifene, droloxifene and hydroxytoremifene. EM-652 was also the most potent inhibitor of the percentage of cycling cancer cells. Synonyms: EM-652; SCH 57068; (2S)-3-(4-Hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidinyl)ethoxy]phenyl]-2H-1-benzopyran-7-ol; (S)-3-(4-Hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidinyl)ethoxy]phenyl]-2H-1-benzopyran-7-ol; (S)-3-(4-hydroxyphenyl)-4-methyl-2-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-2H-chromen-7-ol. Grades: ≥98%. CAS No. 182167-02-8. Molecular formula: C29H31NO4. Mole weight: 457.57. | |
| Acorus gramineus, ext. | Acorus gramineus, ext. is a natural product isolated from Acorus gramineus. Grades: ≥95%. CAS No. 91745-11-8. | |
| Acotiamide hydrochloride trihydrate | Acotiamide, also known as YM-443 and Z-338, is a drug approved in Japan for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. Uses: Cholinesterase inhibitors. Synonyms: N-(2-(diisopropylamino)ethyl)-2-(2-hydroxy-4,5-dimethoxybenzamido)thiazole-4-carboxamide hydrochloride trihydrate; YM443; YM-443; YM 443; Z338; Z-338; Z 338; Acotiamide; Acotiamide hydrochloride trihydrate; Brand name: Acofide. Grades: 98%. CAS No. 773092-05-0. Molecular formula: C21H37ClN4O8S. Mole weight: 541.06. | |
| Ac-Oxytocin | Ac-Oxytocin is an impurity of Oxytocin, which is a mammalian neurohypophysial hormone used as a vasodilator agent. Synonyms: Acetyl-L-cystyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparginyl-L-cystyl-L-leucyl-L-prolyl-L-glycinamide (disulfide bridge between cysteines); Cys(Ac)-Oxytocin; Ac-Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (Disulfide bridge: Cys1-Cys6); Oxytocin, N-acetyl-; N(alpha)-Acetyloxytocin; N-Acetyloxytocin; Oxytocin, 1-(N-acetylcysteine). Grades: ≥95%. CAS No. 10551-48-1. Molecular formula: C45H68N12O13S2. Mole weight: 1049.23. | |
| Ac-PAL-AMC | Ac-PAL-AMC is a fluorogenic substrate for the β1i/LMP2 subunit of the 20S immunoproteasome. It can be cleaved to release the fluorescent moiety 7-amino-4-methylcoumarin (AMC), which can be used to quantify the activity of the β1i/LMP2 subunit of the 20S immunoproteasome. Synonyms: Acetyl-Pro-Ala-Leu-7-amino-4-Methylcoumarin; 1-acetyl-L-prolyl-L-alanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-leucinamide. Grades: ≥95%. CAS No. 1431362-79-6. Molecular formula: C26H34N4O6. Mole weight: 498.6. | |
| Ac-Phe-Gly-pNA | Synonyms: (S)-2-acetamido-N-(2-(4-nitrophenylamino)-2-oxoethyl)-3-phenylpropanamide. Grades: >99%. CAS No. 34336-99-7. Molecular formula: C19H20N4O5. Mole weight: 384.39. | |
| Ac-Pro-Leu-Gly-OH | Synonyms: Glycine, N-[N-(1-acetyl-L-prolyl)-L-leucyl]-; 2-((S)-2-((S)-1-Acetylpyrrolidine-2-carboxamido)-4-methylpentanamido)acetic acid. CAS No. 89626-38-0. Molecular formula: C15H25N3O5. Mole weight: 327.38. | |
| Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt | It is used as a substrate in a rapid, sensitive, continuous spectrophotometric assay for vertebrate collagenase, gelatinase A, and gelatinase B. Synonyms: Glycine, 1-acetyl-L-prolyl-L-leucylglycyl-2-mercapto-4-methylpentanoyl-L-leucyl-, ethyl ester. CAS No. 98992-65-5. Molecular formula: C31H53N5O8S. Mole weight: 655.85. | |
| ACPT-I | ACPT-I, a competitive antagonist for mGluRs, has been found to exhibit anticonvulsant activities. Synonyms: ACPT-1; ACPT 1; ACPT1; (1S,3R,4S)-1-Aminocyclopentane-1,3,4-tricarboxylic acid. Grades: ≥98% by HPLC. CAS No. 194918-76-8. Molecular formula: C8H11NO6. Mole weight: 217.18. | |
| ACPT-II | ACPT-II has been found to be a mGluR antagonist and could probably exhibit neuroprotective effects. Synonyms: (1R,3R,4S)-1-Aminocyclopentane-1,3,4-tricarboxylic acid. Grades: ≥98% by HPLC. CAS No. 195209-04-2. Molecular formula: C8H11NO6. Mole weight: 217.18. | |
| ACP-TMP | ACP-TMP is a derivative of Trimethoprim, which inhibits the enzyme dihydrofolate reductase. Synonyms: 3-Chloro-N- (17- (4- ( (2, 4-diaminopyrimidin-5-yl) methyl) -2, 6-dimethoxyphenoxy) -15-oxo-4, 7, 10-trioxa-14-azaheptadecyl) -4- ( (2- (2-methyl-2- ( (5- (trifluoromethyl) pyridin-2-yl) sulfonyl) propanamido) ethyl) thio) benzamide; Acp-tmp. Molecular formula: C45H58ClF3N8O11S2. Mole weight: 1043.57. | |
| ACR 16 hydrochloride | ACR 16 hydrochloride is a dopaminergic stabilizer (Ki values 17550 nM and 7521 for D2(low) and D2(high), respectively) that state-dependently stabilizes psychomotor activity by the dual actions of functional dopamine D2 receptor antagonism and strengthening of cortical glutamate functions in various settings of perturbed neurotransmission. ACR 16 hydrochloride is used for ameliorating several neurological and psychiatric disorders, including Huntington's disease. Uses: The treatment of neurological and psychiatric disorders. Synonyms: ACR 16 hydrochloride; ACR16 hydrochloride; ACR-16 hydrochloride; Pridopidine Hydrochloride; 4-(3-methylsulfonylphenyl)-1-propylpiperidine hydrochloride. Grades: 99%. CAS No. 882737-42-0. Molecular formula: C15H23NO2S.HCl. Mole weight: 317.87. | |
| Acridine homodimer | Acridine homodimer is a fluorescent nucleic acid stain. Synonyms: Bis-(6-chloro-2-methoxy-9-acridinyl)spermine. CAS No. 57576-49-5. Molecular formula: C38H42Cl2N6O2. Mole weight: 685.69. | |
| Acridine Orange 10-nonyl bromide | Acridine orange 10-nonyl is a metachromatic dye that is used to analyze mitochondria by flow cytometry, characterize multidrug resistance, and measure changes in mitochondrial mass during apoptosis in rat thymocytes. Synonyms: 10-nonyl Acridine Orange; Nonylacridine Orange; 3,6-bis(dimethylamino)-10-nonyl-acridinium bromide. Grades: ≥90%. CAS No. 75168-11-5. Molecular formula: C26H38BrN3. Mole weight: 472.5. | |
| Acridine Orange Base | Acridine orange is a cell-permeable fluorescent probe that stain nucleic acid. Acridine orange is widely used for cell cycle determination and detection of cellular autophagy. Synonyms: 3,6-Acridinediamine, N3,N3,N6,N6-tetramethyl-; N3,N3,N6,N6-tetramethyl-3,6-acridinediamine; Euchrysine; Waxoline Orange A; 3,6-Acridinediamine, N,N,N',N'-tetramethyl-; Acridine, 3,6-bis(dimethylamino)-; 3,6-Bis(dimethylamino)acridine; 3,6-Di(dimethylamino)acridine; Acridine orange free base; Brilliant Acridine Orange E; C.I. 46005B; C.I. Solvent Orange 15; NSC 194350; Solvent Orange 15; Acridine Orange Stain; Acridine Orange. Grades: ≥95%. CAS No. 494-38-2. Molecular formula: C17H19N3. Mole weight: 265.35. | |
| Acridine Orange compd. with zinc chloride | Acridine Orange compd. with zinc chloride is a prominently utilized fluorescent dye in the biomedical realm. Renowned for its intrinsic capacity to stain and visualize an array of cellular constituents ranging from DNA, RNA to acidic organelles, this multifaceted compound holds tremendous value in diagnostic procedures, cancer analysis, and identification of infectious diseases. Its prevalence and significance within these areas render it an indispensable tool of modern scientific inquiry. Synonyms: Basic Orange 14;3,6-Acridinediamine, N3,N3,N6,N6-tetramethyl-, hydrochloride, compd. with zinc chloride (ZnCl2) (1:1:x); 3,6-Acridinediamine, N,N,N',N'-tetramethyl-, monohydrochloride, compd. with zinc chloride; 3,6-Acridinediamine, N,N,N',N'-tetramethyl-, monohydrochloride, compd. with zinc chloride (ZnCl2); Acridine, 3,6-bis(dimethylamino)-, monohydrochloride, compd. with zinc chloride; Zinc chloride (ZnCl2), compd. with N,N,N',N'-tetramethyl-3,6-acridinediamine monohydrochloride; Zinc chloride, compd. with 3,6-bis(dimethylamino)acridine monohydrochloride; Zinc chloride, compd. with N,N,N',N'-tetramethyl-3,6-acridinediamine monohydrochloride; Euchrysine 3RX; N,N,N',N'-Tetramethylacridine-3,6-diamine monohydrochloride compd. with zinc dichloride. CAS No. 10127-02-3. Molecular formula: C17H19N3.xCl2Zn.HCl. Mole weight: 301.81 (free base). | |
| Ac-RLR-AMC trifluoroacetate salt | Ac-RLR-AMC is a fluorogenic substrate for the 26S proteasome. Ac-RLR-AMC is cleaved to release the fluorescent moiety 7-amino-4-methylcoumarin (AMC), which can be used to quantify the trypsin-like activity of 26S proteasomes. Synonyms: Ac-Arg-Leu-Arg-7-amino-4-methylcoumarin; (S)-2-acetamido-5-guanidino-N-((S)-1-(((S)-5-guanidino-1-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-1-oxopentan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)pentanamide, 2,2,2-trifluoroacetate salt. Grades: ≥98%. Molecular formula: C30H46N10O6·CF3COOH. Mole weight: 756.8. | |
| Acrolein dimethyl acetal | Acrolein dimethyl acetal (CAS# 6044-68-4) is a useful research chemical. Synonyms: 3,3-dimethoxyprop-1-ene. CAS No. 6044-68-4. Molecular formula: C5H10O2. Mole weight: 102.13. | |
| Ac-RRRRRRRRRRAAAAAAEEEEEEEEEEEEEE-NH2 | Synonyms: Ac-10R-6A-14E-NH2; Ac-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Ala-Ala-Ala-Ala-Ala-Ala-Glu-Glu-Glu-Glu-Glu-Glu-Glu-Glu-Glu-Glu-Glu-Glu-Glu-Glu-NH2. Molecular formula: C150H253N61O59. Mole weight: 3855.04. | |
| Acrylic acid Polymers | Polyacrylic Acid (PAA) is innoxious and soluble in water, which can be used in situations of alkaline and high concentration without scale sediment. Uses: Paa can be used as scale inhibitor and dispersant in circulating cooling water systems in power plants, iron & steel factories, chemical fertilizer plants, refineries and air conditioning systems. dosage should be in accordance with water quality and equipment materials. when used alone, 1-15 mg/l is preferred. Synonyms: PAA; Carbopol; Carbomer 910; CARBOPOL(R) 940. CAS No. 9003-1-4. Molecular formula: (C3H4O2)n. | |
| Ac-RYYRIK-NH2 acetate | Ac-RYYRIK-NH2 acetate is a potent and partial agonist on ORL1 transfected in CHO cells (Kd = 1.5 nM). Ac-RYYRIK-NH2 is a specific antagonist for the activation of G protein and competitively antagonizes the stimulation of [35S]-GTPgS binding to G proteins by nociceptin/orphanin FQ (noc/OFQ) in membranes and sections of rat brain. Synonyms: Ac-Arg-Tyr-Tyr-Arg-Ile-Lys-NH2.CH3CO2H; N-acetyl-L-arginyl-L-tyrosyl-L-tyrosyl-L-arginyl-L-isoleucyl-L-lysinamide acetic acid. Grades: ≥95%. CAS No. 2863659-08-7. Molecular formula: C46H74N14O11. Mole weight: 999.17. | |
| Ac-RYYRWK-NH2 acetate | Ac-RYYRWK-NH2 acetate is a potent and selective partial agonist of the nociceptin receptor (NOP), which is the endogenous ORL1 receptor agonist. Synonyms: Ac-Arg-Tyr-Tyr-Arg-Trp-Lys-NH2.CH3CO2H; N-acetyl-L-arginyl-L-tyrosyl-L-tyrosyl-L-arginyl-L-tryptophyl-L-lysinamide acetic acid. Grades: ≥95%. CAS No. 2863657-54-7. Molecular formula: C51H73N15O11. Mole weight: 1072.22. | |
| Ac-RYYRWK-NH2 TFA | Ac-RYYRWK-NH2 is a potent and selective partial agonist for the nociceptin receptor (NOP). Synonyms: Ac-Arg-Tyr-Tyr-Arg-Trp-Lys-NH2.TFA; N-acetyl-L-arginyl-L-tyrosyl-L-tyrosyl-L-arginyl-L-tryptophyl-L-lysinamide trifluoroacetic acid; L-Lysinamide, N2-acetyl-L-arginyl-L-tyrosyl-L-tyrosyl-L-arginyl-L-tryptophyl-, mono(trifluoroacetate) (salt). Grades: ≥95%. CAS No. 408305-09-9. Molecular formula: C51H70F3N15O11. Mole weight: 1126.19. | |
| Ac-Ser-Ile-Tyr-Val-Ala-Thr-NH2 | Synonyms: Ac-L-Ser-L-Ile-L-Tyr-L-Val-L-Ala-L-Thr-NH2; acetyl-SIYVAT-NH2; N-acetyl-L-seryl-L-isoleucyl-L-tyrosyl-L-valyl-L-alanyl-L-threoninamide; (2S,3S)-2-((S)-2-acetamido-3-hydroxypropanamido)-N-((S)-1-(((S)-1-(((S)-1-(((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)amino)-1-oxopropan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)amino)-3-(4-hydroxyphenyl)-1-oxopropan-2-yl)-3-methylpentanamide; L-Threoninamide, N-acetyl-L-seryl-L-isoleucyl-L-tyrosyl-L-valyl-L-alanyl-. CAS No. 1401804-68-9. Molecular formula: C32H51N7O10. Mole weight: 693.80. | |
| Ac-Ser-Val-Val-Val-Arg-Thr-NH2 | Synonyms: (S)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-5-guanidino-2-((2S,5S,8S,11S)-11-(hydroxymethyl)-2,5,8-triisopropyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazatetradecanamido)pentanamide; Ac-L-Ser-L-Val-L-Val-L-Val-L-Arg-L-Thr-NH2; acetyl-SVVVRT-NH2; N-acetyl-L-seryl-L-valyl-L-valyl-L-valyl-L-arginyl-L-threoninamide; L-Threoninamide, N-acetyl-L-seryl-L-valyl-L-valyl-L-valyl-L-arginyl-. CAS No. 1401804-69-0. Molecular formula: C30H56N10O9. Mole weight: 700.84. | |
| AcS-PEG3-OH | AcS-PEG3-OH is a PEG linker containing a sulfur acetyl group and a hydroxyl group. The sulfur acetyl group can be removed to produce a thiol moiety. The hydroxyl group can react to further derivatize the compound. The hydrophilic PEG linkers increase the water solubility of the compound in aqueous media. Synonyms: S-acetyl-PEG3-alcohol; S-acetyl-PEG3-OH; Ethanethioic acid, S-[2-[2-(2-hydroxyethoxy)ethoxy]ethyl] ester; S-{2-[2-(2-Hydroxyethoxy)ethoxy]ethyl} ethanethioate; 1- ({2-[2- (2-hydroxyethoxy) ethoxy]ethyl}sulfanyl) ethan-1-one. Grades: ≥95%. CAS No. 153870-20-3. Molecular formula: C8H16O4S. Mole weight: 208.27. | |
| Acs-PEG4-propargyl | Acs-PEG4-propargyl is a PEG linker containing a sulfur acetyl group and a propargyl moiety. The sulfur acetyl group can be deprotected to produce a thiol compound. The propargyl group can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The hydrophilic PEG linker increases the water solubility of the compounds in the aqueous media. Synonyms: S-acetyl-PEG4-Propargyl; Acetylthio-PEG4-Alkyne; S-acetyl-PEG4-alkyne; S-(3,6,9,12-Tetraoxapentadec-14-yn-1-yl) ethanethioate; Ethanethioic acid, S-3,6,9,12-tetraoxapentadec-14-yn-1-yl ester. Grades: ≥95%. CAS No. 1422540-88-2. Molecular formula: C13H22O5S. Mole weight: 290.37. | |
| ACT 335827 | ACT 335827 has been found to be an orexin OX1 receptor antagonist and could probably exhibit anxiolytic effects in vivo. Synonyms: ACT-335827; ACT 335827; ACT335827; (aR,1S)-1-[(3,4-Dimethoxyphenyl)methyl]-3,4-dihydro-6,7-dimethoxy-N-(1-methylethyl)-a-phenyl-2(1H)-isoquinolineacetamide. Grades: ≥98% by HPLC. CAS No. 1354039-86-3. Molecular formula: C31H38N2O5. Mole weight: 518.64. | |
| ACT 462206 | ACT 462206 has been found to be a potent and selective dual orexin receptor antagonist and could exhibit anxiolytic-like activities. Synonyms: ACT-462206; ACT 462206; ACT462206; (2S)-N-(3,5-Dimethylphenyl)-1-[(4-methoxyphenyl)sulfonyl]-2-pyrrolidinecarboxamide. Grades: ≥99% by HPLC. CAS No. 1361321-96-1. Molecular formula: C20H24N2O4S. Mole weight: 388.48. | |
| ACTB-1003 | ACTB-1003 is an oral kinase inhibitor with multiple modes of action, targeting cancer mutations via FGFR inhibition FGFR1, angiogenesis through inhibition of VEGFR2, Tie-2, and induces apoptosis likely by targeting RSK and p70S6K. It is highly active with dose-dependent tumor growth inhibition in cell lines with FGFR genetic alterations - OPM2 human multiple myeloma and the murine leukemia Ba/F3-TEL-FGFR1. Synonyms: ACTB1003; ACTB 1003; ACTB-1003. Grades: >98%. CAS No. 939805-30-8. Molecular formula: C27H26F5N7O3. Mole weight: 591.53. | |
| ACTH 11-24 acetate | ACTH(11-24) is a fragment of the adrenocorticotropic hormone (ACTH) and an antagonist of the adrenocorticotropic hormone (ACTH) receptor that induces cortisol release. Synonyms: ACTH (11-24) acetate; Adrenocorticotropic Hormone (11-24) acetate. Molecular formula: C79H138N24O18. Mole weight: 1712.09. | |
| ACTH (1-13) (human, mouse, rat, porcine, bovine, ovine) trifluoroacetate salt | ACTH (1-13) is a peptide fragment of adrenocorticotropic hormone, a peptide hormone found in the brain that is involved in the biological stress response. Synonyms: SYSMEHFRWGKPV-OH. Grades: ≥98%. Molecular formula: C75H106N20O19S·xCF3COOH. Mole weight: 1623.83. | |
| ACTH (1-14) acetate | ACTH (1-14) acetate is a fragment of the adrenocorticotropic hormone that regulates the production of cortisol and androgens. Synonyms: Adrenocorticotropic Hormone Fragment 1-14 acetate; H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-OH.CH3CO2H; L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophyl-glycyl-L-lysyl-L-prolyl-L-valyl-glycine acetic acid; α1-14-Corticotropin acetate; α-Melanotropin (Rana catesbeiana) acetate; α-MSH (chicken) acetate; ACTH 1-14 acetate; α1-14-ACTH acetate. Grades: ≥95%. Molecular formula: C79H113N21O22S. Mole weight: 1740.96. | |
| ACTH (1-17) (human, mouse, rat, porcine, bovine, ovine) trifluoroacetate salt | ACTH (1-17) is a peptide fragment of adrenocorticotropic hormone, a peptide hormone found in the brain that is involved in the biological stress response. Synonyms: Adrenocorticotropic hormone (1-17); SYSMEHFRWGKPVGKKR-OH; Cortrophin; Corticotrophin. Grades: ≥98%. Molecular formula: C95H145N29O23S·xCF3COOH. Mole weight: 2093.42. | |
| ACTH (2-24) (human, bovine, rat) | ACTH (2-24) (human, bovine, rat) is an impurity of tetracosactide, a synthetic peptide analog of the human adrenocorticotropic hormone that stimulates cortisol production. Synonyms: Tetracosactide (2-24); H-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-OH; Corticotropin (2-24); L-tyrosyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophyl-glycyl-L-lysyl-L-prolyl-L-valyl-glycyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-prolyl-L-valyl-L-lysyl-L-valyl-L-tyrosyl-L-proline. Grades: ≥95%. CAS No. 67654-32-4. Molecular formula: C133H205N39O29S. Mole weight: 2846.36. | |
| ACTH (3-24) (human, bovine, rat) | ACTH (3-24) (human, bovine, rat) is an impurity of tetracosactide, a synthetic peptide analog of the human adrenocorticotropic hormone that stimulates cortisol production. Synonyms: Tetracosactide (3-24); H-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-OH; L-Seryl-L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-L-valylglycyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-prolyl-L-valyl-L-lysyl-L-valyl-L-tyrosyl-L-proline; ACTH (3-24), human, bovine, mouse, ovine, porcine, rabbit, rat. Grades: ≥95%. CAS No. 1036763-00-4. Molecular formula: C124H196N38O27S. Mole weight: 2683.19. | |
| ACTH (4-10) (human, mouse, rat, porcine, bovine, ovine) trifluoroacetate salt | Adrenocorticotropic hormone (ACTH) (4-10) is an endogenous peptide fragment of ACTH, a peptide hormone produced by the anterior pituitary gland that is involved in the biological stress response. Synonyms: Adrenocorticotropic hormone (4-10); Corticotropin (4-10); H-Met-Glu-His-Phe-Arg-Trp-Gly-OH. Grades: ≥95%. Molecular formula: C44H59N13O10S·xCF3COOH. Mole weight: 962.09. | |
| ACTH (4-10) Trifluoroacetate | ACTH (4-10) is a fragment of Adrenocorticotropic Hormone (ACTH), a melanocortin 4 (MC4R) receptor agonist. Synonyms: Adrenocorticotropic Hormone (ACTH) (4-10) TFA. Molecular formula: C46H60F3N13O12S. Mole weight: 1076.12. | |
| ACTH (6-24) (human, mouse, rat, porcine, bovine, ovine) trifluoroacetate salt | ACTH (6-24) is a peptide fragment of adrenocorticotropic hormone, a peptide hormone found in the brain that is involved in the biological stress response. Synonyms: HFRWGKPVGKKRRPVKVYP; Corticotropin-(6-24)-peptide. Grades: ≥95%. CAS No. 33512-65-1. Molecular formula: C111H175N35O21·xCF3COOH. Mole weight: 2335.8. | |
| Ac-Thr-Ile-Nle-psi(CH2NH)Nle-Gln-Arg-NH2 | Ac-Thr-Ile-Nle-psi(CH2NH)Nle-Gln-Arg-NH2 is an HIV-1 protease inhibitor whose sequence is derived from the cleavage site of the viral gag-pol poly-protein. Electron density studies have shown that this inhibitor binds to the active site of the HIV-1 protease. Synonyms: MVT-101; N-acetyl-Thr-Ile-Nle-psi(CH2-NH)-Nle-Gln-Arg-amide; N-acetyl-threonyl-isoleucyl-norleucyl-psi(CH2-NH)-norleucyl-glutaminyl-argininamide; N-{(2S)-2-[(N-Acetyl-L-threonyl-L-isoleucyl)amino]hexyl}-L-norleucyl-L-glutaminyl-L-argininamide; L-Argininamide, N-[(2S)-2-[[(2S,3S)-2-[[(2S,3R)-2-(acetylamino)-3-hydroxy-1-oxobutyl]amino]-3-methyl-1-oxopentyl]amino]hexyl]-L-norleucyl-L-glutaminyl-. Grades: 95%. CAS No. 128657-47-6. Molecular formula: C35H67N11O8. Mole weight: 769.98. | |
| Activated Charcoal | Activated Charcoal is commonly used to purify and decolorize starch-based sweeteners such as glucose syrup, dextrose and isoglucose. Synonyms: Carbon. Grades: > 99.0%. CAS No. 7440-44-0. Molecular formula: C. Mole weight: 12.011. | |
| Activated Protein C (390-404), human acetate | Activated Protein C (390-404) human, a peptide of the activated protein C (a vitamin K-dependent serine protease), effectively inhibits the anticoagulant activity of APC. Molecular formula: C93H134N22O25. Mole weight: 1960.19. | |
| Ac-Trp-Glu-His-Asp-AMC | Synonyms: AC-WEHD-AMC; Acetyl-L-Tryptophyl-L-Glutamyl-L-Histidyl-L-Aspartic Acid Alpha-(4-Methylcoumaryl-7-Amide); Caspase 1 (Ice) Substrate 3M, Fluorogenic; N-Acetyl-Trp-Glu-His-Asp-7-amino-4-methylcoumarin. CAS No. 189275-74-9. Molecular formula: C38H40N8O11. Mole weight: 784.77. | |
| Ac-Tyr-Val-Ala-Asp-AMC | Ac-Tyr-Val-Ala-Asp-AMC is a fluorogenic substrate for caspase-1 (ICE). Synonyms: Ac-YVAD-AMC; N-Acetyl-Tyr-Val-Ala-Asp-7-amido-4-methylcoumarin; 3-[2-[[2-[[2-acetamido-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]propanoylamino]-4-[(4-methyl-2-oxochromen-7-yl)amino]-4-oxobutanoic acid; acetyl-Tyr-Val-Ala-Asp-4-methylcoumaryl-7-amide. CAS No. 149231-65-2. Molecular formula: C33H39N5O10. Mole weight: 665.69. | |
| Ac-Tyr-Val-Ala-Asp-pNA | Ac-Tyr-Val-Ala-Asp-pNA is a substrate for caspase-1 and caspase-4. Synonyms: Ac-YVAD-pNA; N-Acetyl-Tyr-Val-Ala-Asp-p-nitroanilide; N-Acetyl-L-tyrosyl-L-valyl-L-alanyl-N-(4-nitrophenyl)-L-alpha-asparagine. CAS No. 149231-66-3. Molecular formula: C29H36N6O10. Mole weight: 628.63. | |
| Acumapimod | Acumapimod is a P38 mitogen-activated protein kinase inhibitor with IC50 value of less than 1 μM for p38&alpha. Phase II clinical trials for the treatment of Chronic obstructive pulmonary disease are on-going. Uses: Chronic obstructive pulmonary disease. Synonyms: BCT-197; BCT197; BCT 197; BCT197A2201; Acumapimod;3-(5-amino-4-(3-cyanobenzoyl)-1H-pyrazol-1-yl)-N-cyclopropyl-4-methylbenzamide. Grades: 98%. CAS No. 836683-15-9. Molecular formula: C22H19N5O2. Mole weight: 385.42. | |
| Ac-Val-Arg-Pro-Arg-AMC | Ac-Val-Arg-Pro-Arg-AMC is a fluorogenic substrate for Arabidopsis thaliana metacaspase-9 (AtMC9) (kcat/Km = 4.6·105 M-1s-1). Synonyms: 7-[(Ac-Val-Arg-Pro-Arg-)Amino]-4-methylcoumarin; Ac-VRPR-AMC; N-Acetyl-L-valyl-L-arginyl-L-prolyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-argininamide; (S)-1-((S)-2-((S)-2-acetamido-3-methylbutanamido)-5-guanidinopentanoyl)-N-((S)-5-guanidino-1-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-1-oxopentan-2-yl)pyrrolidine-2-carboxamide; L-Argininamide, N-acetyl-L-valyl-L-arginyl-L-prolyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-. Grades: ≥95%. CAS No. 919515-51-8. Molecular formula: C34H51N11O7. Mole weight: 725.85. | |
| Ac-Val-Asp-Val-Ala-Asp-aldehyde (pseudo acid) | Ac-VDVAD-CHO is an inhibitor of caspase-2, -3, and -7 (Kis = 3.5, 1, and 7.5 nM, respectively). Synonyms: Ac-VDVAD-CHO; N-acetyl-L-valyl-L-alpha-aspartyl-L-valyl-L-alanyl-L-aspart-1-al; N-Acetyl-L-valyl-L-α-aspartyl-L-valyl-N-[(2S)-1-carboxy-3-oxo-2-propanyl]-L-alaninamide; L-Alaninamide, N-acetyl-L-valyl-L-α-aspartyl-L-valyl-N-[(1S)-2-carboxy-1-formylethyl]-; Caspase-2 Inhibitor (Aldehyde). Grades: ≥95%. CAS No. 194022-51-0. Molecular formula: C23H37N5O10. Mole weight: 543.57. | |
| Ac-Val-Glu-Ile-Asp-aldehyde (pseudo acid) | Ac-VEID-CHO is an inhibitor of caspase-6 (IC50 = 16.2 nM). It is selective for caspase-6 over caspase-7 (IC50 = 162.1 nM) but can also inhibit caspase-3 (IC50 = 13.6 nM). Synonyms: N-acetyl-L-valyl-L-alpha-glutamyl-L-isoleucyl-L-aspart-1-al; N-acetyl-Val-Glu-Ile-Asp-aldehyde; N-Acetyl-L-valyl-L-alpha-glutamyl-N-[(2S)-1-carboxy-3-oxo-2-propanyl]-L-isoleucinamide; L-Isoleucinamide, N-acetyl-L-valyl-L-α-glutamyl-N-[(1S)-2-carboxy-1-formylethyl]-; N-Acetyl-Val-Glu-Ile-Asp-al; (4S,7S,10S,13S)-10-((S)-sec-butyl)-7-(2-carboxyethyl)-13-formyl-4-isopropyl-2,5,8,11-tetraoxo-3,6,9,12-tetraazapentadecan-15-oic acid; Caspase-6 Inhibitor; Ac-VEID-CHO. Grades: ≥95%. CAS No. 319494-39-8. Molecular formula: C22H36N4O9. Mole weight: 500.54. | |
| Ac-Val-Tyr-Lys-NH2 | Synonyms: Ac-VYK-NH2; N-acetyl-L-valyl-L-tyrosyl-L-lysinamide; (S)-2-((S)-2-((S)-2-acetamido-3-methylbutanamido)-3-(4-hydroxyphenyl)propanamido)-6-aminohexanamide. Grades: ≥95%. CAS No. 884009-99-8. Molecular formula: C22H35N5O5. Mole weight: 449.54. | |
| Ac-VDVAD-AFC | Ac-VDVAD-AFC is a fluorogenic substrate whose amino acids VDVAD have been shown to be a preferred cleavage site for caspase-2. Caspase activity can be quantified by fluorescent detection of free AFC (7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm. Synonyms: N-Acetyl-Val-Asp-Val-Ala-Asp-7-amino-4-Trifluoromethylcoumarin; N-acetyl-L-valyl-L-α-aspartyl-L-valyl-L-alanyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine. Grades: ≥95%. CAS No. 210344-94-8. Molecular formula: C33H41F3N6O12. Mole weight: 770.7. | |
| Ac-VDVAD-CHO trifluoroacetate salt | Cas No. 194022-51-0. | |
| Ac-VEID-AMC | Ac-VEID-AMC is a fluorogenic substrate for caspase-6 and related proteases including caspase-8. Caspase activity can be quantified by fluorescent detection of free AMC (7-amino-4-methylcoumarin), which is excited at 340-360 nm and emits at 440-460 nm. Synonyms: N-Acetyl-Val-Glu-Ile-Asp-7-amido-4-Methylcoumarin; N-acetyl-L-valyl-L-α-glutamyl-L-isoleucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-α-asparagine. Grades: ≥95%. CAS No. 219137-97-0. Molecular formula: C32H43N5O11. Mole weight: 673.7. | |
| Ac-VEID-CHO trifluoroacetate salt | Cas No. 319494-39-8. | |
| Ac-WLA-AMC | Ac-WLA-AMC is a fluorogenic substrate for the β5c subunit of the 20S proteasome. Ac-WLA-AMC is cleaved to release the fluorescent moiety 7-amino-4-methylcoumarin (AMC), which can be used to quantify the β5c subunit activity. Synonyms: Acetyl-Trp-Leu-Ala-7-amino-4-Methylcoumarin; N-acetyl-L-tryptophyl-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-alaninamide. Grades: ≥95%. CAS No. 1104011-59-7. Molecular formula: C32H37N5O6. Mole weight: 587.7. | |
| ACY-775 | ACY-775 is a selective Histone Deacetylase 6 (HDAC6) inhbiitor with low nanomolar potency and a selectivity of 60- to 1500-fold over class I HDACs. ACY-775 has the antidepressant-like properties of other HDAC inhibitors. Uses: Antidepressant. Synonyms: ACY-775; ACY 775; ACY775; 2-((1-(3-Fluorophenyl)cyclohexyl)amino)-N-hydroxypyrimidine-5-carboxamide. Grades: 95%. CAS No. 1375466-18-4. Molecular formula: C17H19FN4O2. Mole weight: 330.36. | |
| Acyline | Acyline is a novel GnRH antagonist found in animal studies to be a potent suppressor of circulating gonadotropin and testosterone (T) levels. Synonyms: MER-104; MER104; MER 104. CAS No. 170157-13-8. Molecular formula: C80H102ClN15O14. Mole weight: 1533.23. | |
| Ac-YVAD-AFC | Ac-YVAD-AFC is a fluorogenic substrate for caspase-1 and caspase-4. Caspase activity can be quantified by fluorescent detection of free AFC (7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm. Synonyms: Caspase-1 Substrate VI (Fluorogenic); Ac-Tyr-Val-Ala-Asp-7-amino-4-Trifluoromethlcoumarin; N-acetyl-L-tyrosyl-L-valyl-L-alanyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine. Grades: ≥95%. CAS No. 219137-85-6. Molecular formula: C33H36F3N5O10. Mole weight: 719.66. | |
| Ac-YVAD-CHO | Ac-YVAD-CHO is a selective inhibitor of interleukin-1β converting enzyme (ICE; Caspase-1). Uses: Cysteine proteinase inhibitors. Synonyms: Acetyl-tyrosyl-valyl-alanyl-aspartal; Ac-Tyr-Val-Ala-Asp-H; N-acetyl-Tyr-Val-Ala-Asp-aldehyde; (S)-N-Acetyl-L-tyrosyl-L-valyl-N-(2-carboxy-1-formylethyl)-L-alaninamide. Grades: ≥98%. CAS No. 143313-51-3. Molecular formula: C23H32N4O8. Mole weight: 492.52. | |
| AD57 | AD57 is a multikinase inhibitor that inhibits RET, BRAF, S6K and Src. It is used in cancer therapeutic. Synonyms: 1-(4-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)phenyl)-3-(3-(trifluoromethyl)phenyl)urea. Grades: >98.0%. CAS No. 1093380-42-7. Molecular formula: C22H20F3N7O. Mole weight: 455.45. | |
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