BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Abz-Gly-Ile-Val-Arg-Ala-Lys(Dnp)-OH | Abz-Gly-Ile-Val-Arg-Ala-Lys(Dnp)-OH is a very efficient and selective FRET substrate for human cathepsin B (Km = 5.9 μM, kcat = 43 s-1, kcat/Km = 7288 mM-1s-1), with kcat/Km values of 133.3, 100, 32, 17, and 75 mM-1s-1 for cathepsin K, L, V, X, and cruzain, respectively. Synonyms: H-2Abz-Gly-Ile-Val-Arg-Ala-Lys(Dnp)-OH; Abz-GIVRAK(Dnp); L-Lysine, N-(2-aminobenzoyl)glycyl-L-isoleucyl-L-valyl-L-arginyl-L-alanyl-N6-(2,4-dinitrophenyl)-; N-(2-Aminobenzoyl)glycyl-L-isoleucylvalyl-L-arginyl-L-alanyl-N6-(2,4-dinitrophenyl)-L-lysine. Grades: ≥95%. CAS No. 827044-38-2. Molecular formula: C41H61N13O12. Mole weight: 928.02. |  |
| Abz-LFK(Dnp)-OH trifluoroacetate salt | Abz-LFK(Dnp)-OH trifluoroacetate salt is an angiotensin-converting enzyme (ACE) fluorescent peptide substrate that binds specifically to the C domain of ACE. It has been used to investigate the development of novel antibacterial calixarene derivatives, as well as the efficacy and toxicity of antimicrobial peptide M33 as a possible antimicrobial agent for lung infections and sepsis. Synonyms: O-Aminobenzoic acid-Leu-Phe-Lys(DNP)-OH trifluoroacetate salt; Abz-Leu-Phe-Lys-DNP trifluoroacetate salt; (2-aminobenzoyl)-L-leucyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-L-lysine trifluoroacetic acid; N-(2-Aminobenzoyl)-L-leucyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-L-lysine trifluoroacetate (1:1); L-Lysine, N-(2-aminobenzoyl)-L-leucyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-, compd. with 2,2,2-trifluoroacetic acid (1:1); (2S)-2-[[(2S)-2-([(2S)-2-[(2-Aminobenzoyl)amino]-4-methylpentanoyl]amino)-3-phenylpropanoyl]amino]-6-(2,4-dinitroanilino)hexanoic acid trifluoroacetate. Grades: ≥97% by HPLC. CAS No. 1217437-31-4. Molecular formula: C34H41N7O9.C2HF3O2. Mole weight: 805.76. | |
| Abz-Ser-Pro-3-nitro-Tyr-OH | Abz-Ser-Pro-3-nitro-Tyr-OH, a selective internal quenching fluorescence (FRET) substrate for angiotensin-converting enzyme 2 (ACE2), has potential application in the high-throughput screening of ACE2 inhibitors (Km = 23 μM, kcat/Km = 3.5·104 M-1s-1). Synonyms: H-2Abz-Ser-Pro-Tyr(3-NO2)-OH; (2-aminobenzoyl)-L-seryl-L-prolyl-3-nitro-L-tyrosine; L-Tyrosine, N-(2-aminobenzoyl)-L-seryl-L-prolyl-3-nitro-. Grades: ≥95%. CAS No. 553644-01-2. Molecular formula: C24H27N5O9. Mole weight: 529.51. | |
| AC 186 | AC 186, also called GTPL8897, a diphenyl substituted cyclohexane derivatives, decreases Aβ levels in combination with ACP-105 in a rat model of Alzheimer's disease. Uses: Anti-alzheimer agents; amyloid-β inhibitor. Synonyms: 4-[4,4-difluoro-1-(2-fluorophenyl)cyclohexyl]phenol; GTPL8897; SCHEMBL14672438; AC-186; AC 186; AC186; AKOS025147323; 4-[4,4-difluoro-1-(2-fluorophenyl)cyclohexyl]phenol; AC 186|4-[4,4-Difluoro-1-(2-fluorophenyl)cyclohexyl]phenol. CAS No. 1421854-16-1. Molecular formula: C18H17F3O. Mole weight: 306.32. | |
| AC 187 acetate | AC 187 acetate is a potent amylin receptor antagonist (IC50 = 0.48 nM) displaying 38- and 400-fold selectivity over calcitonin and CGRP receptors respectively. It inhibits amyloid β-induced neurotoxicity by attenuating the activation of initiator and effector caspases in vitro. It increases glucagon secretion, accelerates gastric emptying, alters plasma glucose levels, and increases food intake in vivo. Synonyms: Ac-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Asn-Thr-Tyr-NH2.CH3CO2H; N-acetyl-L-valyl-L-leucyl-glycyl-L-lysyl-L-leucyl-L-seryl-L-glutaminyl-L-alpha-glutamyl-L-leucyl-L-histidyl-L-lysyl-L-leucyl-L-glutaminyl-L-threonyl-L-tyrosyl-L-prolyl-L-arginyl-L-threonyl-L-asparagyl-L-threonyl-glycyl-L-seryl-L-asparagyl-L-threonyl-L-tyrosinamide acetic acid. Grades: ≥95%. Molecular formula: C129H209N37O42. Mole weight: 2950.26. | |
| AC1903 | AC1903 is an inhibitor of transient receptor potential canonical channel 5 (TRPC5; IC50 = 14.7 μM). Synonyms: 1-benzyl-N-(furan-2-ylmethyl)benzimidazol-2-amine. Grades: ≥95%. CAS No. 831234-13-0. Molecular formula: C19H17N3O. Mole weight: 303.4. | |
| AC260584 | AC260584 is a potent and selective muscarinic M1 receptor allosteric agonist (pEC50 = 7.6). Studies indicated that AC260584 has a behavioral profile consistent with antipsychotic-like efficacy with the potential to improve cognitive performance and shows reduced liability for extrapyramidal symptoms. Synonyms: 4-[3-(4-butylpiperidin-1-yl)propyl]-7-fluoro-1,4-benzoxazin-3-one; 4-(3-(4-butylpiperidin-1-yl)propyl)-7-fluoro-4H-benzo(1,4)oxazin-3-one; AC 260584; AC-260584; AC260584. CAS No. 560083-42-3. Molecular formula: C20H29FN2O2. Mole weight: 348.45. | |
| AC 265347 | AC 265347 is a CaSR biased allosteric modulator (pEC50 = 7.8-8.1) that bias signaling towards the accumulation of PERK1/2 and IP1. AC 265347 stimulates CaSR signaling in cellular proliferation and phosphatidyl inositol (PI) hydrolysis assays. It significantly activates human GABAB or type I PTH receptors. Synonyms: AC 265347; AC-265347; AC265347; α-(2,4-Dimethylphenyl)-α-methyl-2-benzothiazolemethanol; 1-(1,3-benzothiazol-2-yl)-1-(2,4-dimethylphenyl)ethanol. Grades: ≥99% by HPLC. CAS No. 1253901-26-6. Molecular formula: C17H17NOS. Mole weight: 283.39. | |
| Ac(2-9) Leuprolide | Ac(2-9) Leuprolide is an impurity of Leuprolide, which is a synthetic nonapeptide analog of gonadotropin-releasing hormone used as an antineoplastic agent, a gonadotropin-releasing hormone agonist, and an anti-estrogen. Synonyms: Ac-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt; Acetyl-L-histidyl-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide; Ac-His Leuprolide(2-9). Molecular formula: C56H81N15O11. Mole weight: 1140.36. | |
| AC 4 | AC 4 is a photoswitchable TRPV1 channel blocker (IC50 = 3.1 μM) that converts TRPV1 channels into photoreceptors. Synonyms: AC 4; AC4; AC-4; 1, 3, 4, 5-Tetrahydro-7, 8-dihydro-N-[2-[4-[2-[4- (trifluoromethyl) phenyl]diazenyl]phenyl]ethyl]-2H-2-benzazepine-2-carbothioamide. Grades: ≥98% by HPLC. CAS No. 1459809-09-6. Molecular formula: C26H25F3N4O2S. Mole weight: 514.56. | |
| AC410 | AC410 is a Janus kinase 2 (JAK2) inhibitor with Kd of 0.18 nM. AC410 is selective for JAK2 and Kd is 2.5 nM for JAK1 and 5nM for JAK3. Phase I for the treatment of Autoimmune disorders and Inflammation is on-going. Uses: Autoimmune disorders; inflammation. Synonyms: AC410; AC 410; AC-410; (S)-(4-fluorophenyl)(4-((5-methyl-1H-pyrazol-3-yl)amino)quinazolin-2-yl)methanol;1361415-86-2 (HCl). Grades: 98%. CAS No. 1361415-84-0. Molecular formula: C19H16FN5O. Mole weight: 349.40. | |
| Ac4ManDBCO | Ac4ManDBCO could metabolically label LS174T colon cancer cells with DBCO groups and subsequently mediate the targeted internalization of azido-/Cy5-NCs via Click chemistry in vitro. In vivo PET/CT and fluorescence dual-modal imaging studies further verified that labeling of LS174T tumors with Ac4ManDBCO could significantly enhance the tumor accumulation of azido-modified silica NCs. Molecular formula: C33H34N2O11. Mole weight: 634.22. | |
| AC 55649 | AC 55649 is a potent and isoform-selective RARβ2 receptor agonist (pEC50 = 6.9, 5.7 and 5.6 at RARβ2, RARβ1 and RARα, respectively). It causes inhibition of proliferation in breast cancer cell line MCF-7. Synonyms: AC 55649; AC-55649; AC55649; 4'-Octyl-[1,1'-biphenyl]-4-carboxylic acid; 4-(4-Octylphenyl)benzoic acid. Grades: ≥99% by HPLC. CAS No. 59662-49-6. Molecular formula: C21H26O2. Mole weight: 310.44. | |
| AC-90179 hydrochloride | AC-90179 hydrochloride is a selective inverse agonist of the 5-HT2A receptor and is used as an atypical antipsychotic to alleviate vasoconstriction induced by hallucinogens. Synonyms: 2-(4-Methoxyphenyl)-N-(4-methylbenzyl)-N-(1-methylpiperidin-4-yl)acetamide hydrochloride; Benzeneacetamide, 4-methoxy-N-[(4-methylphenyl)methyl]-N-(1-methyl-4-piperidinyl)-, hydrochloride (1:1); Benzeneacetamide, 4-methoxy-N-[(4-methylphenyl)methyl]-N-(1-methyl-4-piperidinyl)-, monohydrochloride; 2-(4-Methoxyphenyl)-N-(4-methylbenzyl)-N-(1-methylpiperidin-4-yl)acetamide hydrochloride; AC-90179 HCl; AC 90179 hydrochloride; AC90179 hydrochloride. Grades: ≥95%. CAS No. 359878-19-6. Molecular formula: C23H31ClN2O2. Mole weight: 402.96. | |
| Ac9-25 acetate | Ac9-25 acetate is an N-terminal peptide of Annexin I (AI/Lipocortin I) that inhibits leukocyte extravasation. It stimulates neutrophil NADPH oxidase activation by acting as a formyl peptide receptor 1 (FPR1) ligand. Synonyms: L-Lysine, N2-acetyl-L-glutaminyl-L-alanyl-L-tryptophyl-L-phenylalanyl-L-isoleucyl-L-α-glutamyl-L-asparaginyl-L-α-glutamyl-L-α-glutamyl-L-glutaminyl-L-α-glutamyl-L-tyrosyl-L-valyl-L-glutaminyl-L-threonyl-L-valyl-, acetate; N2-Acetyl-L-glutaminyl-L-alanyl-L-tryptophyl-L-phenylalanyl-L-isoleucyl-L-α-glutamyl-L-asparaginyl-L-α-glutamyl-L-α-glutamyl-L-glutaminyl-L-α-glutamyl-L-tyrosyl-L-valyl-L-glutaminyl-L-threonyl-L-valyl-L-lysine acetate; Ac-Gln-Ala-Trp-Phe-Ile-Glu-Asn-Glu-Glu-Gln-Glu-Tyr-Val-Gln-Thr-Val-Lys-OH acetate. Grades: ≥95%. Molecular formula: C101H147N23O35. Mole weight: 2243.38. | |
| Ac-AAVALLPAVLLALLAP-DEVD-CHO trifluoroacetate salt | Ac-AAVALLPAVLLALLAP-DEVD-CHO is a composite of Ac-DEVD-CHO, a peptide inhibitor of caspase-3 and -7, and a cell-permeable hydrophobic sequence derived from K-FGF. Synonyms: Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Asp-Glu-Val-Asp-CHO; Ac-AAVALLPAVLLALLAP-DEVD-aldehyde; Ac-AAVALLPAVLLALLAPDEVD-CHO; ?Caspase-3 Inhibitor I; DEVD-CHO-CPP 32. Grades: ≥95%. Molecular formula: C94H158N20O27·xCF3COOH. Mole weight: 2000.42. | |
| Ac-AAVALLPAVLLALLAP-IETD-CHO trifluoroacetate salt | Ac-AAVALLPAVLLALLAP-IETD-CHO is a composite of Ac-IETD-CHO, a peptide inhibitor of caspase-8, and a cell-permeable hydrophobic sequence derived from K-FGF. Synonyms: Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Ile-Glu-Thr-Asp-CHO; Caspase-8 Inhibitor I. Grades: ≥95%. Molecular formula: C95H162N20O26·xCF3COOH. Mole weight: 2000.40. | |
| Ac-AAVALLPAVLLALLAP-VAD-CHO trifluoroacetate salt | Ac-AAVALLPAVLLALLAP-VAD-CHO is a composite of Ac-VAD-CHO, a non-selective caspase inhibitor, and a cell-permeable hydrophobic sequence derived from K-FGF. Synonyms: Caspase Inhibitor II; Ac-AAVALLPAVLLALLAP-VAD-aldehyde; Ac-AAVALLPAVLLALLAPVAD-CHO. Grades: ≥95%. Molecular formula: C88H151N19O22·xCF3COOH. Mole weight: 1827.3. | |
| Ac-Abu-Tle-Leu-Gln-AMC | Ac-Abu-Tle-Leu-Gln-AMC is a fluorogenic substrate targeting the SARS-CoV and SARS-CoV-2 Main Protease (Mpro). Synonyms: Acetyl-L-α-aminobutyroyl-L-tert-leucyl-L-leucyl-L-glutamine α-(4-methylcoumaryl-7-amide). Grades: ≥95%. Molecular formula: C33H48N6O8. Mole weight: 656.77. | |
| Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Ile-Glu-Thr-Asp-aldehyde | Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Ile-Glu-Thr-Asp-aldehyde, a potent and reversible caspase-8 inhibitor, enables cell permeability by linking to a nonpolar CPP corresponding to the Kaposi fibroblast growth factor (FGF) signaling peptide sequence. Synonyms: Caspase-8 Inhibitor I, Cell Permeable; N-Acetyl-L-alanyl-L-alanyl-L-valyl-L-alanyl-L-leucyl-L-leucyl-L-prolyl-L-alanyl-L-valyl-L-leucyl-L-leucyl-L-alanyl-L-leucyl-L-leucyl-L-alanyl-L-prolyl-L-isoleucyl-L-α-glutamyl-N-[(2S)-1-carboxy-3-oxo-2-propanyl]-L-threoninamide; N-Acetyl-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Ile-Glu-Thr-Asp-al; L-Threoninamide, N-acetyl-L-alanyl-L-alanyl-L-valyl-L-alanyl-L-leucyl-L-leucyl-L-prolyl-L-alanyl-L-valyl-L-leucyl-L-leucyl-L-alanyl-L-leucyl-L-leucyl-L-alanyl-L-prolyl-L-isoleucyl-L-α-glutamyl-N-[(1S)-2-carboxy-1-formylethyl]-. Grades: ≥95%. CAS No. 886462-83-5. Molecular formula: C95H162N20O26. Mole weight: 2000.42. | |
| Acanthopanaxoside B | Acanthopanaxoside B is a triterpenoid isolated from Acanthopanax senticosus. Grades: 0.98. CAS No. 915792-03-9. Molecular formula: C61H98O27. Mole weight: 1263.43. | |
| Acarbose EP Impurity A | An impurity of Acarbose, a medication used for the treatment of diabetes mellitus type 2. Synonyms: O-4,6-dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-enyl]amino]-α-Dglucopyranosyl-(1?4)-O-α-D-glucopyranosyl-(1?4)-Darabino-hex-2-ulopyranose; Acarbose Impurity A. Molecular formula: C26H43NO18. Mole weight: 645.60. | |
| Acarbose EP Impurity B | An impurity of Acarbose, a medication used for the treatment of diabetes mellitus type 2. Synonyms: (1R,4R,5S,6R)-4,5,6-trihydroxy-2-(hydroxymethyl)cyclohex-2-enyl 4-O-[4,6-dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-enyl]amino]-α-D-glucopyranosyl]-α-D-glucopyranoside; Acarbose Impurity B. Molecular formula: C26H43NO17. Mole weight: 641.62. | |
| Acarbose EP Impurity E | An impurity of Acarbose, a medication used for the treatment of diabetes mellitus type 2. Synonyms: O-4,6-dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-enyl]amino]-α-Dglucopyranosyl-(1?4)-O-α-D-glucopyranosyl-(1?4)-O-α-D-glucopyranosyl-(1?4)-D-arabino-hex-2-ulopyranose; 4-O-α-acarbosyl-D-fructopyranose; Acarbose Impurity E. Molecular formula: C31H53NO23. Mole weight: 807.75. | |
| Ac-Arg-Ala-Asp-Ala-Asp-Ala-Asp-Ala-Arg-Ala-Asp-Ala-Asp-Ala-Asp-Ala-NH2 | Grades: ≥95%. Molecular formula: C62H99N23O29. Mole weight: 1630.59. | |
| AC-ARG-ARG-PRO-TYR-ILE-LEU-OH | Synonyms: Acetylneurotensin (8-13); N-Acetyl-neurotensin-(8-13); L-Leucine, N-(N-(N-(1-(N2-(N2-acetyl-L-arginyl)-L-arginyl)-L-prolyl)-L-tyrosyl)-L-isoleucyl)-. CAS No. 74853-69-3. Molecular formula: C40H66N12O9. Mole weight: 859.03. | |
| Ac-Arg-Cys-Met-5-aminopentanoyl-Arg-Val-Tyr-5-aminopentanoyl-Cys-NH2, (Disulfide bond) | Ac-Arg-Cys-Met-5-aminopentanoyl-Arg-Val-Tyr-5-aminopentanoyl-Cys-NH2 is a full competitive MCH-1 receptor antagonist and has no agonist effect on human MCH-1 receptor even at micromolar concentrations (Kb = 3.6 nM). Synonyms: Ac-Arg-Cys-Met-Ava-Arg-Val-Tyr-Ava-Cys-NH2 (Disulfide bridge: Cys2-Cys9); L-Cysteinamide, N2-acetyl-L-arginyl-L-cysteinyl-L-methionyl-5-aminopentanoyl-L-arginyl-L-valyl-L-tyrosyl-5-aminopentanoyl-, cyclic (2?9)-disulfide. Grades: ≥95%. CAS No. 353487-64-6. Molecular formula: C49H82N16O11S3. Mole weight: 1167.49. | |
| Ac-Arg-Gly-Lys-AMC | Ac-Arg-Gly-Lys-AMC is a control for the two step histone deacetylase assay with Ac-Arg-Gly-Lys(Ac)-AMC. It corresponds to the product of the deacetylase reaction, which is subsequently cleaved by trypsin. Synonyms: Ac-RGK-AMC; N2-Acetyl-L-arginylglycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-Lysinamide; N2-Acetyl-L-arginylglycyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-lysinamide; (S)-2-(2-((S)-2-acetamido-5-guanidinopentanamido)acetamido)-6-amino-N-(4-methyl-2-oxo-2H-chromen-7-yl)hexanamide. Grades: ≥95%. CAS No. 660846-99-1. Molecular formula: C26H38N8O6. Mole weight: 558.64. | |
| Ac-Arg-Leu-Arg-AMC | Ac-Arg-Leu-Arg-AMC is a fluorogenic substrate for the determination of the trypsin-like activity of purified proteasomes (Km = 78 μM). Synonyms: Ac-RLR-AMC; N2-Acetyl-L-arginyl-L-leucyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-argininamide; L-Argininamide, N2-acetyl-L-arginyl-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-. Grades: ≥95%. CAS No. 929903-87-7. Molecular formula: C30H46N10O6. Mole weight: 642.76. | |
| Ac-Arg-NH2 | Synonyms: Ac-Arg-Nh2 Salt; N-acetylarginamide; N-alpha-Acetyl-L-arginine amide; (S)-2-acetamido-5-guanidinopentanamide. CAS No. 64365-27-1. Molecular formula: C8H17N5O2. Mole weight: 215.25. | |
| Ac-Asp(5)-AVP | Ac-Asp(5)-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: Ac-Asp(5)-Vasopressin; N-Ac-Asp(5)-AVP; [Cys(Ac)1-Asp(5)]-Argipressin; Ac-Cys-Tyr-Phe-Gln-Asp-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); Acetyl-L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-aspartyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide. CAS No. 2594426-06-7. Molecular formula: C48H66N14O14S2. Mole weight: 1127.26. | |
| Ac-Asp-Glu-Val-Asp-pNA | Ac-Asp-Glu-Val-Asp-pNA is the caspase-3 chromogenic substrate, and its cleavage can be monitored at 405 nm. Synonyms: Ac-DEVD-pNA; N-acetyl-L-alpha-aspartyl-L-alpha-glutamyl-L-valyl-N4-(4-nitrophenyl)-L-asparagine; L-α-Asparagine, N-acetyl-L-α-aspartyl-L-α-glutamyl-L-valyl-N-(4-nitrophenyl)-; (2S,5S,8S,11S)-8-(2-carboxyethyl)-11-(carboxymethyl)-5-isopropyl-2-(2-((4-nitrophenyl)amino)-2-oxoethyl)-4,7,10,13-tetraoxo-3,6,9,12-tetraazatetradecan-1-oic acid. Grades: ≥95%. CAS No. 189684-50-2. Molecular formula: C26H34N6O13. Mole weight: 638.59. | |
| Ac-AVP | Ac-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: Vasopressin, N-acetyl-8-L-arginine-; Vasopressin, 1-(N-acetyl-L-cysteine)-8-arginine; Vasopressin, 8-acetylarginine; 1-Acetylcysteine-8-arginine-vasopressin; N-Acetyl-Vasopressin; N-acetyl-L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide; Ac-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); Ac-Vasopressin; N-Acetyl-8-L-argininevasopressin. CAS No. 38106-69-3. Molecular formula: C48H67N15O13S2. Mole weight: 1126.28. | |
| ACBC | ACBC has been found to be a NMDA receptor partial agonist and could probably affect the signal transmission in the CNS. Synonyms: 1-Aminocyclobutane-1-carboxylic acid. Grades: ≥98% by HPLC. CAS No. 22264-50-2. Molecular formula: C5H9NO2. Mole weight: 115.13. | |
| ACBI1 | ACBI1 is a potent PROTAC degrader of BAF ATPase subunits SMARCA2 and SMARCA4, also degrades the polybromo-associated BAF (PBAF) complex member PBRM1, with DC50s of 6 nM, 11 nM and 32 nM for SMARCA2, SMARCA4 and PBRM1 in MV-4-11 cells, respectively. ACBI1 is composed of a bromodomain ligand, a linker, and the E3 ubiquitin ligase VHL. ACBI1 can induce anti-proliferative effects and apoptosis. Synonyms: ACBI 1; ACBI-1; (2S,4R)-N-(2-(2-(4-((4-(3-amino-6-(2-hydroxyphenyl)pyridazin-4-yl)piperazin-1-yl)methyl)phenoxy)ethoxy)-4-(4-methylthiazol-5-yl)benzyl)-1-((S)-2-(1-fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxamide. CAS No. 2375564-55-7. Molecular formula: C49H58FN9O7S. Mole weight: 936.12. | |
| Ac-DEVD-AMC | Ac-DEVD-AMC is a fluorogenic substrate for caspase-3. Caspase activity can be quantified by fluorescent detection of free AMC (7-amino-4-methylcoumarin), which is excited at 340-360 nm and emits at 440-460 nm. Synonyms: N-Acetyl-Asp-Glu-Val-Asp-7-amido-4-Methylcoumarin; N-acetyl-L-α-aspartyl-L-α-glutamyl-L-valyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-α-asparagine. Grades: ≥95%. CAS No. 169332-61-0. Molecular formula: C30H37N5O13. Mole weight: 675.64. | |
| Ac-DEVD-CHO | Ac-DEVD-CHO is a potent aldehyde inhibitor of Group II caspases with Ki values of 0.2 nM and 0.3 nM for for caspase-3 and caspase-7, respectively. Weak inhibition for caspase-2. Uses: Cysteine proteinase inhibitors. Synonyms: N-acetyl-asp-glu-val-asp-al; Ac-Asp-Glu-Val-Asp-Aldehyde; L-Valinamide,N-acetyl-L-a-aspartyl-L-a-glutamyl-N-(2-carboxy-1-formylethyl)-. Grades: 95 %. CAS No. 169332-60-9. Molecular formula: C20H30N4O11. Mole weight: 502.47. | |
| Ac-DEVD-CHO acetate | Ac-DEVD-CHO acetate is a specific inhibitor of Caspase-3. Synonyms: Caspase-3 Inhibitor I; N-acetyl-asp-glu-val-asp-al acetate; Ac-Asp-Glu-Val-Asp-al acetate; Ac-DEVD-al.CH3CO2H; L 761191 acetate; MF 191 acetate; N-acetyl-L-alpha-aspartyl-L-alpha-glutamyl-L-valyl-L-aspart-1-al acetate; N-Acetyl-L-α-aspartyl-L-α-glutamyl-N-[(1S)-2-carboxy-1-formylethyl]-L-valinamide acetate. Grades: ≥95%. Molecular formula: C22H34N4O13. Mole weight: 562.52. | |
| Ac-DEVD-CMK | Ac-DEVD-CMK is a cell-permeable, and irreversible inhibitor of caspase-3 as well as caspase-6, -7, -8, and -10. It is commonly used at concentrations up to 100 μM to examine the role of caspase-3-dependent apoptosis in biological systems. Synonyms: Ac-Asp-Glu-Val-Asp-chloromethylketone; Caspase-3 Inhibitor III; N-acetyl-Asp-Glu-Val-Asp-chloromethylketone; N-Acetyl-L-α-aspartyl-L-α-glutamyl-N-[(2S)-1-carboxy-4-chloro-3-oxo-2-butanyl]-L-valinamide; (2S,5S,8S,11S)-8-(2-carboxyethyl)-11-(carboxymethyl)-2-(2-chloroacetyl)-5-isopropyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazatetradecane-1-carboxylic acid. Grades: ≥98%. CAS No. 285570-60-7. Molecular formula: C21H31ClN4O11. Mole weight: 550.95. | |
| Ac-dG Phosphoramidite | Cas No. 2417251-95-5. Molecular formula: C42H50N7O8P. Mole weight: 811.88. | |
| Ac-DMQD-CHO trifluoroacetate salt | Ac-DMQD-CHO is a peptide inhibitor of caspase-3 (IC50 = 39 nM). It is selective for caspase-3 over caspase-1 and caspase-8 (IC50s = 148 and 1,100 nM, respectively). Ac-DMQD-CHO inhibits apoptosis induced by camptothecin in immortalized human T/C 28a4 chondrocytes and primary human chondrocytes. In vivo, Ac-DMQD-CHO (1 mg/kg, i.v.) reduces the number of apoptotic cells, cavitation, and demyelination in a rat model of traumatic injury to the spinal cord. Synonyms: Ac-Asp-Met-Gln-Asp-CHO; Caspase-3 Inhibitor. Grades: ≥95%. Molecular formula: C20H31N5O10S·xCF3COOH. Mole weight: 533.6. | |
| Ac-DNLD-AMC | Ac-DNLD-AMC is a fluorogenic substrate for caspase-3. It is cleaved by caspase-3 to release the fluorescent moiety 7-amino-4-methylcoumarin (AMC), which can be used to quantify caspase-3 activity. Synonyms: N-Acetyl-Asp-Asn-Leu-Asp-7-amido-Methylcoumarin; N-acetyl-L-α-aspartyl-L-asparaginyl-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-α-asparagine. Grades: ≥95%. CAS No. 958001-92-8. Molecular formula: C30H38N6O12. Mole weight: 674.7. | |
| ACDPP hydrochloride | The hydrochloride salt form of ACDPP, which has been found to be a mGluR-5 antagonist. Synonyms: 3-Amino-6-chloro-5-dimethylamino-N-2-pyridinylpyrazinecarboxamide hydrochloride. Grades: ≥99% by HPLC. CAS No. 37804-11-8. Molecular formula: C12H13ClN6O.HCl. Mole weight: 329.19. | |
| ACe-1 | Ac-1 is a modified ceramide with azophenyl groups used for optical control of N-acyl chains. Ceramide is a pro-apoptotic sphingolipid. Ceramide's generation can regulate the structure of the lipid rafts. Synonyms: N-[ (E) -4- (4- ( (4-butylphenyl) diazenyl) phenyl) butanoyl]-D-erythro-sphingosine; Benzenebutanamide, 4-[(1E)-2-(4-butylphenyl)diazenyl]-N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-; 4-(4-((E)-(4-butylphenyl)diazenyl)phenyl)-N-((2S,3R,E)-1,3-dihydroxyoctadec-4-en-2-yl)butanamide. Grades: >99%. CAS No. 2260670-55-9. Molecular formula: C38H59N3O3. Mole weight: 605.89. | |
| ACEA | ACEA is a selective cannabinoid receptor 1 (CB1R) agonist (Ki = 1.4 nM) with much higher affinity over CB2R. CB1 receptors are mainly expressed in the central and peripheral nervous system. Synonyms: N-(2-chloroethyl)icosa-5,8,11,14-tetraenamide; 5,8,11,14-Eicosatetraenamide,N-(2-chloroethyl)-, (5Z,8Z,11Z,14Z); (5Z,8Z,11Z,14Z)-N-(2-Chloroethyl)-5,8,11,14-eicosatetraenamide; Arachidonyl-2'-chloroethylamide. CAS No. 220556-69-4. Molecular formula: C22H36ClNO. Mole weight: 365.986. | |
| Aceanthrenequinone | Aceanthrenequinone (CAS# 6373-11-1) is a useful research chemical. Synonyms: aceanthrylene-1,2-dione. CAS No. 6373-11-1. Molecular formula: C16H8O2. Mole weight: 232.23. | |
| Acebutolol hydrochloride | Acebutolol is a β-adrenergic receptors antagonist used in the treatment of hypertension, angina pectoris and cardiac arrhythmias. Synonyms: Acebutolol hydrochloride. Grades: >98%. CAS No. 34381-68-5. Molecular formula: C18H28N2O4.HCl. Mole weight: 372.89. | |
| Aceclidine | Aceclidine is an agent that is used for treating glaucoma by reducing intraocular pressure. Aceclidine is a modulator of M3 muscarinic acetylcholine receptor. Synonyms: Quinuclidin-3-yl acetate; 3-Acetoxyquinuclidine; Glaucostat; 3-Quinuclidinol acetate (ester); NSC 657843. CAS No. 827-61-2. Molecular formula: C9H15NO2. Mole weight: 169.22. | |
| Aceclidine hydrochloride | Aceclidine is an agonist of muscarinic receptors. Synonyms: Aceclidine HCl; 3-Acetoxyquinuclidine hydrochloride; Glaucostat. Grades: ≥95%. CAS No. 6109-70-2. Molecular formula: C9H15NO2·HCl. Mole weight: 205.7. | |
| Acein | Acein is a high-affinity angiotensin-converting enzyme (ACE) ligand with a Kd of 2.79 nM. It potentiates NMDA+ D-serine-induced dopamine release from the striatum in vivo and striatal slices in vitro. Synonyms: L-Alanine, L-prolyl-L-prolyl-L-threonyl-L-threonyl-L-threonyl-L-lysyl-L-phenylalanyl-L-alanyl-; L-Prolyl-L-prolyl-L-threonyl-L-threonyl-L-threonyl-L-lysyl-L-phenylalanyl-L-alanyl-L-alanine; H-Pro-Pro-Thr-Thr-Thr-Lys-Phe-Ala-Ala-OH. Grades: ≥95%. CAS No. 2022202-76-0. Molecular formula: C43H68N10O13. Mole weight: 933.06. | |
| Acein acetate | Acein acetate is a high-affinity angiotensin-converting enzyme (ACE) ligand with a Kd of 2.79 nM. It potentiates NMDA+ D-serine-induced dopamine release from the striatum in vivo and striatal slices in vitro. Synonyms: H-Pro-Pro-Thr-Thr-Thr-Lys-Phe-Ala-Ala-OH.CH3CO2H; L-prolyl-L-prolyl-L-threonyl-L-threonyl-L-threonyl-L-lysyl-L-phenylalanyl-L-alanyl-L-alanine acetate. Grades: ≥95%. Molecular formula: C45H72N10O15. Mole weight: 993.11. | |
| Acenaphthenequinone | Acenaphthenequinone (CAS# 82-86-0) is used in the synthesis of AChE inhibitory agents. Also used in the synthesis of turn-on sensors for cysteine/homocysteine and its application in bioimaging. Synonyms: acenaphthylene-1,2-dione. Grades: 98+ %. CAS No. 82-86-0. Molecular formula: C12H6O2. Mole weight: 182.17. | |
| Acenaphthylene | Polycyclic aromatic hydrocarbons as carcinogenic agents. Uses: Used in insecticides and fungicides and in the manufacture of dyes and plastics; present in crude oil and coal tar; produced during combustion (including natural fires), petroleum refining, and coal tar distillation; has been detected in the atmosphere of a lumber creosote impregnation plant, at the coal preparation area of a solvent refined coal pilot plant, in an aluminum plant, and in smokehouses; used as an intermediate for resins. Synonyms: acenaphthylene. Grades: 95 %. CAS No. 208-96-8. Molecular formula: C12H8. Mole weight: 152.19. | |
| Ac-Endothelin-1 (16-21), human acetate | Ac-Endothelin-1 (16-21), human acetate, the principal peptide of the endothelin family, has been shown to have a variety of biological activities in both vascular and nonvascular tissues, including the heart, the kidney, and the central nervous system. Synonyms: Ac-His-Leu-Asp-xiIle-xiIle-Ala(indol-2-yl)-OH.CH3CO2H; N-acetyl-L-histidyl-L-leucyl-L-alpha-aspartyl-(3xi)-L-isoleucyl-(3xi)-L-isoleucyl-3-indol-2-yl-L-alanine acetic acid. Grades: ≥95%. Molecular formula: C43H63N9O12. Mole weight: 898.01. | |
| aceprometazine | Aceprometazine is a Histamine H1 receptor antagonist as an approved drug. It can be used in combination with meprobamate for the treatment of sleep disorders such as Insomnia. Uses: Insomnia. Synonyms: Mepronizine; Acepromethazine; Aceprometazine; Aceprometazina; Aceprometazinum; Aceprometazinum; Aceprometazina;1-[10-[2-(Dimethylamino)propyl]-10H-phenothiazin-2-yl]ethanone;Acepromethazine. Grades: 95%. CAS No. 13461-01-3. Molecular formula: C19H22N2OS. Mole weight: 326.46. | |
| ACET | ACET, a potent and selective GluR5-containing kainate receptor antagonist, has been found to exhibit activities in blocking induction of NMDA receptor-independent long term potentiation (LTP) at some extent. Synonyms: (S)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxy-5-phenylthiophene-3-yl-methyl)-5-methylpyrimidine-2,4-dione. Grades: ≥98% by HPLC. CAS No. 936095-50-0. Molecular formula: C20H19N3O6S. Mole weight: 429.45. | |
| Acetamide,2-[(4-methoxyphenyl)amino]-2-thioxo- | Acetamide,2-[(4-methoxyphenyl)amino]-2-thioxo- (CAS# 71369-81-8 ) is a useful research chemical. Synonyms: 2-((4-Methoxyphenyl)amino)-2-thioxoacetamide; 2-(4-Methoxyphenylamino)-2-thioxoacetamide; 2-Thioxo-2-(4-methoxyanilino)acetamide; 2-(4-Methoxyanilino)-2-thioxo-acetamide; 1-[ (4-Methoxyphenyl) carbamothioyl]formamide. CAS No. 71369-81-8. Molecular formula: C9H10N2O2S. Mole weight: 210.25. | |
| Acetamidine hydrochloride | Acetamidine hydrochloride (CAS# 124-42-5) is a compound useful in organic synthesis. Synonyms: ethanimidamide;hydrochloride. Grades: > 95.0 %T. CAS No. 124-42-5. Molecular formula: C2H7ClN2. Mole weight: 94.54. | |
| Acethydrazide | Acethydrazide (CAS# 1068-57-1) is a metabolite of Isoniazid (I821450) an antibiotic for treatment of Mycobacterium tuberculosis, inhibits mycolic acid biosynthesis. Synonyms: acetohydrazide. Grades: 97 %. CAS No. 1068-57-1. Molecular formula: C2H6N2O. Mole weight: 74.08. | |
| Acetic acid calcium salt | Acetic acid calcium salt is used as a preservative in oral and topical preparations. Oral calcium acetate is used as a complexing agent for hyperphosphatemia in dialysis patients. It is also used as a stabilizer, buffer and sequestrant in the food industry. Synonyms: Calcium Acetate; Brown Acetate; Calcium Diacetate; E 263; Gray Acetate; Lime Acetate; Lime Pyrolignite; PhosLo; Royen; Sanopan; Sorbo-Calcion; Teltozan. Grades: 98%. CAS No. 62-54-4. Molecular formula: C4H6CaO4. Mole weight: 158.17. | |
| Acetogenin | Acetogenin is an extensively utilized natural compound aiding in the research of cancer. It is adept in impeding the proliferation of diverse tumor cells. Synonyms: Isodesaacetyluvaricin. Grades: 95%. CAS No. 136033-39-1. Molecular formula: C37H66O6. Mole weight: 606.91. | |
| Acetone azine | Acetone Azine acts as a general reagent used in the synthesis of pharmaceutically active agents such as dihydropyridazine-3(2H)-ones. Synonyms: N-(propan-2-ylideneamino)propan-2-imine. CAS No. 627-70-3. Molecular formula: C6H12N2. Mole weight: 112.17. | |
| Acetone oxime | Acetone Oxime was one of the reagents used as a part of preparation of arylbenzoxazoles as potent and selective estrogen receptor-β ligands. Synonyms: N-propan-2-ylidenehydroxylamine. Grades: Techincal grade. CAS No. 127-06-0. Molecular formula: C3H7NO. Mole weight: 73.09. | |
| Acetonyltriphenylphosphonium chloride | Acetonyltriphenylphosphonium chloride (CAS# 1235-21-8 ) is a useful research chemical. Synonyms: acetonyltriphenyl-phosphoniuchloride; (2-OXOPROPYL)-TRIPHENYLPHOSPHONIUM CHLORIDE; ACETONYLTRIPHENYLPHOSPHONIUM CHLORIDE; AURORA KA-1148; ACETONYLTRIPHENYLPHOSPHONIUM CHLORIDE, 9 8%; Acetonyltriphenylphosphonium chloride,99%. Grades: > 98.0 % (T). CAS No. 1235-21-8. Molecular formula: C21H20ClOP. Mole weight: 354.81. | |
| Acetophenone | Acetophenone is used for fragrance in soaps and perfumes, as a flavoring agent in foods, and as a solvent for plastics and resins. Synonyms: 1-Feniletanone; 1-Phenyl-1-ethanone; 1-Phenylethanone; Acetophenon; Acetylbenzene; Hypnon; Hypnone; Methyl Phenyl Ketone; NSC 7635; NSC 98542; Phenyl Methyl Ketone. Grades: ≥95%. CAS No. 98-86-2. Molecular formula: C8H8O. Mole weight: 120.15. | |
| Acetophenone oxime | Acetophenone oxime (CAS# 613-91-2) is a useful research chemical compound. Synonyms: (NE)-N-(1-phenylethylidene)hydroxylamine. Grades: 98 %. CAS No. 613-91-2. Molecular formula: C8H9NO. Mole weight: 135.16. | |
| Acetoxyacetic acid | Acetoxyacetic acid (CAS# 13831-30-6) is a versatile organic building block, used in the synthesis of pharmaceutical compounds, including inhibitors and therapeutic agents. It can be used for the synthesis of analogs of 5-Aminolevulinic Acid, which are potential inhibitors of ALA dehydratase (porphobilinogen synthase), an early enzyme of tetrapyrrole biosynthesis. Synonyms: 2-acetyloxyacetic acid. CAS No. 13831-30-6. Molecular formula: C4H6O4. Mole weight: 118.09. | |
| Acetoxyacetone | Acetoxyacetone (CAS# 592-20-1) is an building block in the synthesis of various pharmaceutical and organic compounds. Synonyms: 2-oxopropyl acetate. Grades: Practical. CAS No. 592-20-1. Molecular formula: C5H8O3. Mole weight: 116.12. | |
| Acetoxyacetyl chloride | Acetoxyacetyl chloride (CAS# 13831-31-7) is a compound useful in organic synthesis. Synonyms: (2-chloro-2-oxoethyl) acetate. Grades: 95 %. CAS No. 13831-31-7. Molecular formula: C4H5ClO3. Mole weight: 136.53. | |
| Acetylaconitine | Acetylaconitine is a diterpenoid alkaloid isolated from the roots of Aconitum kusnezoffii Reichb. It is used in analgesia in rats for the treatment of chronic pain and rheumatoid arthritis. Uses: Acetylaconitine is used in analgesia in rats for the treatment of chronic pain and rheumatoid arthritis. Synonyms: Aconitine 3-acetate; (16beta)-3,8-bis(acetyloxy)-20-ethyl-13,15-dihydroxy-1,6,16-trimethoxy-4-(methoxymethyl)aconitan-14-yl benzoate. Grades: >98%. CAS No. 77181-26-1. Molecular formula: C36H49NO12. Mole weight: 687.77. | |
Our database is helping our users find suppliers everyday.
