BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
×
Product
Description
Suppliers Website
(3S,4R)-3,4-Dihydroxy-2-methyl-D-proline
(3S,4R)-3,4-Dihydroxy-2-methyl-D-proline, an essential compound omnipresent in the biomedical domain, assumes a pivotal mantle as an elemental constituent when crafting an array of pharmaceuticals and medicines. This prodigious entity holds sway over the intricate pathogenesis of diverse afflictions such as malignant tumors, cardiovascular afflictions, and neurological maladies. Molecular formula: C6H11NO4. Mole weight: 161.16.
An impurity of Paroxetine which is a selective serotonin reuptake inhibitor. Synonyms: Paroxetine Impurity 20. Grade: 98%. CAS No. 324023-99-6. Molecular formula: C20H23NO3. Mole weight: 325.40.
(3S,4R)-3-(Hydroxymethyl)-3,4-pyrrolidinediol
(3S,4R)-3-(Hydroxymethyl)-3,4-pyrrolidinediol is a salient intermediate integral to bioactive compound construction. In particular, the production of HIV protease inhibitors can leverage this compound, thereby forging a pathway toward effective HIV infection treatment. Synonyms: isoDAB; 3,4-Pyrrolidinediol, 3-(hydroxymethyl)-, (3S,4R)-. CAS No. 1241760-33-7. Molecular formula: C5H11NO3. Mole weight: 133.15.
(3S,4R,5R)-1-(4-(8-Chloro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11(6H)-ylidene)piperidin-1-yl)-3,4,5,6-tetrahydroxyhexan-2-one is a degradation product of Desloratadine, which is a tricyclic H1 inverse agonist used to treat allergies. Synonyms: D-Fructose, 1-[4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinyl]-1-deoxy-; 1-[4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinyl]-1-deoxy-D-fructose. Grade: 98%. CAS No. 1419972-49-8. Molecular formula: C25H29ClN2O5. Mole weight: 472.96.
One of the impurities of Tacrolimus, which is a kind of immunosuppressant and could restrain the activity of FK-506 binding protein. Synonyms: 16,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,15,19-trihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14-methoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-, (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-; (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25. Grade: ≥95%. CAS No. 132172-14-6. Molecular formula: C43H67NO12. Mole weight: 789.99.
(3S,4'R)-Benidipine HCl
(3S,4'R)-Benidipine HCl is an exceedingly potent calcium channel antagonist extensively utilized within the biomedical industry exhibiting its utmost significance in the research of hypertension and angina pectoris, debilitating ailments of vascular origin. Accomplishing its therapeutic goals with remarkable efficacy, this compound conspicuously unleashes its formidable action by discerningly obstructing L-type calcium channels, ultimately abating vascular resistance whilst studying blood pressure levels. Synonyms: 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, methyl 1-(phenylmethyl)-3-piperidinyl ester, [S-(R*,S*)]-. Grade: > 95%. CAS No. 119009-45-9. Molecular formula: C28H32N3O6Cl. Mole weight: 542.04.
(3S,4R)-Dihydro-3-hydroxy-3-methyl-4-tert-butyldimethylsilyloxy-2(3H)-furanone is an intriguing biomedicine compound characterized by its intricate chemical structure, currently demonstrating immense potential as a therapeutic agent targeting a plethora of ailments. Synonyms: 2-C-Methyl-3-O-tert-butyldimethylsilyloxy-D-threono-1,4-lactone. Molecular formula: C11H22O4Si. Mole weight: 246.38.
(3S,4R)-Tofacitinib
(3S,4R)-Tofacitinib is a less active enantiopure stereoisomer of the JAK3 inhibitor Tofacitinib. Synonyms: Tofacitinib Impurity B; 3-((3S,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile. Grade: >98%. CAS No. 1092578-48-7. Molecular formula: C16H20N6O. Mole weight: 312.27.
(3S,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine
One of the impurities of Tofacitinib, which is a Janus kinase inhibitor and could be used against rheumatoid arthritis. Synonyms: Tofacitinib Impurity DT. CAS No. 1354621-59-2. Molecular formula: C14H22N2. Mole weight: 218.34.
(3S,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride is an impurity of Tofacitinib, a medication used to treat rheumatoid arthritis, psoriatic arthritis and ulcerative colitis. Synonyms: Tofacitinib impurity G; Tofacitinib Impurity 02; cis-1-Benzyl-3-(methylamino)-4-methylpiperidine dihydrochloride. CAS No. 1354486-07-9. Molecular formula: C14H24Cl2N2. Mole weight: 291.3.
(3S,4S)-2,3-Dihydroxy-2-methylpentanoic acid-1,4-lactone (mixture of diastereoisomers)
(3S,4S)-2,3-Dihydroxy-2-methylpentanoic acid-1,4-lactone (mixture of diastereoisomers) is an intriguing and multifaceted molecular entity that has garnered immense attention within the biomedical realm. This captivating compound displays distinctively auspicious properties, rendering it an indispensable tool in combatting a range of afflictions, including cardiovascular disorders and thrombotic conditions. The intricate nature of its mechanisms of action, coupled with its profound versatility, has unequivocally solidified its indispensable stature within the biomedicine domain. Molecular formula: C6H10O4. Mole weight: 146.14.
An impurity of Orlistat. Orlistat is a pancreatic lipase inhibitor that aids in weight loss by blocking the absorption of dietary fats in the gastrointestinal tract. Synonyms: (3S,4S)-3-Hexyl-4-((S)-2-hydroxytridecyl)oxetan-2-one. CAS No. 68711-40-0. Molecular formula: C22H42O3. Mole weight: 354.57.
(3S,4S,3'R)-Ezetimibe
A stereoisomer of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L9) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: RSS-Ezetimibe. Grade: > 95%. CAS No. 1478664-18-4. Molecular formula: C24H21F2NO3. Mole weight: 409.44.
(3S,4S,3'S)-Ezetimibe
A stereoisomer of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L9) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3S,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone; (3S,4S)-1-(4-Fluorophenyl)-3-[(S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one; S,S,S-Ezetimibe; Ezetimibe (3S,4S,3'S)-Isomer; SSS-Ezetimibe; Ezetimibe Impurity SSS. Grade: >95%. CAS No. 1593543-07-7. Molecular formula: C24H21F2NO3. Mole weight: 409.44.
An intermediate of Suzetrigine, which is an oral selective NaV1.8 pain signal inhibitor developed for the treatment of moderate-to-severe acute pain. Synonyms: 2-Furanol, 3-(3,4-difluoro-2-methoxyphenyl)tetrahydro-4,5-dimethyl-5-(trifluoromethyl)-, 2-acetate, (3S,4S,5R)-. Grade: ≥95%. CAS No. 2875066-46-7. Molecular formula: C16H17F5O4. Mole weight: 368.30.
(3S,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-L-proline, a pivotal biomolecular entity extensively employed in the biomedical sector, exhibits indispensability in diverse pharmaceutical compositions aimed at combating afflictions such as malignancies, hepatic fibrosis, and cardiovascular disorders. Its distinctive configuration and characteristics confer it with considerable potential for therapeutic applications, thereby facilitating the progression of pioneering curative modalities for these pathological states. Molecular formula: C6H11NO5. Mole weight: 177.16.
(3S,4S,5R)-6-(6-Amino-2-chloro-9H-purin-9-yl)-5-fluorotetrahydro-2H-pyran-3,4-diol is an impurity of Clofarabine, Second generation purine nucleoside analog, antimetabolite that inhibits DNA synthesis and resists deamination by adenosine deaminase. Antineoplastic. Synonyms: Clofarabine Impurity. Molecular formula: C10H11ClFN5O3. Mole weight: 303.68.
(3S,4S,5R)-Dihydro-4,5-bis(phenylmethoxy)-2(3H)-furanone, a remarkable biomedicine exhibiting exceptional pharmacological attributes, stands as a compelling solution for the treatment of diverse ailments. Embracing its potent nature, this compound undertakes the role of managing afflictions such as inflammation, pain, and cancer. It showcases the ability to specifically target enzymes or receptors linked to these conditions, thereby imparting therapeutic advantages and contributing to groundbreaking advancements in the realm of biomedical investigation. Molecular formula: C18H18O4. Mole weight: 298.34.
(3S,4S,5R)-Ethyl 5-Acetoxy-4-hydroxy-3-(pentan-3-yloxy)cyclohex-1-enecarboxylate is an intermediate in the synthesis of Oseltamivir, which is an antiviral drug used to treat and prevent influenza A and B viruses. Synonyms: Ethyl (3S,4S,5R)-5-acetoxy-4-hydroxy-3-(3-pentanyloxy)-1-cyclohexene-1-carboxylate; 1-Cyclohexene-1-carboxylic acid, 5-(acetyloxy)-3-(1-ethylpropoxy)-4-hydroxy-, ethyl ester, (3S,4S,5R)-. CAS No. 347378-70-5. Molecular formula: C16H26O6. Mole weight: 314.37.
(3S,4S,5R)-Ethyl 5-Acetoxy-4-((methylsulfonyl)oxy)-3-(pentan-3-yloxy)cyclohex-1-enecarboxylate is an intermediate of enantiomeric derivatives of Oseltamivir, which can be used in COVID19-related research. Synonyms: Ethyl (3S,4S,5R)-5-acetoxy-4-[(methylsulfonyl)oxy]-3-(3-pentanyloxy)-1-cyclohexene-1-carboxylate; 1-Cyclohexene-1-carboxylic acid, 5-(acetyloxy)-3-(1-ethylpropoxy)-4-[(methylsulfonyl)oxy]-, ethyl ester, (3S,4S,5R)-. CAS No. 347378-72-7. Molecular formula: C17H28O8S. Mole weight: 392.46.
(3S,4S,5S)-3,4-Dihydroxy-5-(hydroxymethyl)-D-proline, also known as (3S,4S,5S)-DHP, is an indispensable and highly significant molecule in the field of biomedicine. Its exceptional antioxidant attributes render it an optimal contender for mitigating ailments associated with oxidative stress. Notably, (3S,4S,5S)-DHP finds extensive utility in the formulation of pharmaceuticals targeting cardiovascular disorders, neurodegenerative pathologies, and select malignancies. Furthermore, its pivotal role in fostering wound healing and orchestrating tissue restoration cannot be undermined. Synonyms: D-Proline, 3,4-dihydroxy-5-(hydroxymethyl)-, (3S,4S,5S)-. CAS No. 1225455-73-1. Molecular formula: C6H11NO5. Mole weight: 177.16.
(3S,4S,5S)-4,5-O-Isopropylidene-3-O-tert-butyldimethylsilyl-1-nonyl-3,4,5-piperidinetriol, named as TBDPIPN, stands as an indispensable and prominent compound within the biomedical realm. Its profound significance lies in its pivotal contribution towards the advancements of innovative pharmacological interventions intended for the holistic treatment of an array of ailments. From debilitating cardiovascular conditions to menacing diabetes and neurodegenerative afflictions, TBDPIPN demonstrates a remarkable potential in ameliorating such maladies. In the landscape of drug discovery and extensive biomedicine research, this compound's distinctive chemical configuration and inherent properties render it an invaluable asset. Its presence accentuates the possibilities of exploring novel therapeutic avenues, thereby enriching the interdisciplinary facets of biomedical science. Molecular formula: C23H47NO3Si. Mole weight: 413.72.
(3S,4S,5S)-Dihydro-3,4,5-trihydroxy-2(3H)-furanone is synthesized from D-Ribonolactone, which is a sugar lactone as inhibitor of E. coli β-galactosidase. Synonyms: 2R,3S-Dihydroxy-4-oxo-butanoic Acid. CAS No. 1106851-69-7. Molecular formula: C4H6O5. Mole weight: 134.09.
(3S,4S)-Tofacitinib
(3S,4S)-Tofacitinib is a less active enantiopure stereoisomer of the JAK3 inhibitor Tofacitinib. Synonyms: Tofacitinib Impurity C; 3-((3S,4S)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile. Grade: >98%. CAS No. 1092578-47-6. Molecular formula: C16H20N6O. Mole weight: 312.27.
(3S,4S)-Tofacitinib Citrate
(3S,4S)-Tofacitinib is a less active enantiopure stereoisomer of the JAK3 inhibitor Tofacitinib. Synonyms: 2-hydroxypropane-1,2,3-tricarboxylic acid; 3-[(3S,4S)-4-methyl-3-[methyl({7H-pyrrolo[2,3-d]pyrimidin-4-yl})amino]piperidin-1-yl]-3-oxopropanenitrile; 3-((3S,4S)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile 2-hydroxypropane-1,2,3-tricarboxylate. CAS No. 2174011-55-1. Molecular formula: C22H28N6O8. Mole weight: 504.50.
(3S,5R)-4-[5-([1,1'-Biphenyl]-4-ylmethyl)-3-methyl-2-oxopyrrolidin-1-yl]-4-oxobutanoic acid is an impurity of Sacubitril, an endopeptidase inhibitor that is effective in the treatment of hypertension and heart failure. Synonyms: 4-[(3R,5S)-5-(4-Biphenylylmethyl)-3-methyl-2-oxo-1-pyrrolidinyl]-4-oxobutanoic acid. CAS No. 2216746-87-9. Molecular formula: C22H23NO4. Mole weight: 365.422.
An impurity of Pitavastatin, an HMG-CoA reductase inhibitor that lowers LDL cholesterol and triglycerides and increases HDL cholesterol in the blood. Synonyms: 6-Heptenoic acid, 7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-, (3S,5R,6E)-; (3S,5R,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic acid; (3S,5R,E)-7-(2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3,5-dihydroxyhept-6-enoic acid. Grade: 95%. CAS No. 254452-86-3. Molecular formula: C25H24FNO4. Mole weight: 421.46.
(3S,5R)-Pitavastatin Calcium
A metabolite of Pitavastatin which is a potent inhibitor of HMG-CoA reductase (Ki = 1.7 nM). Synonyms: ent-NK-104; Pitavastatin 3S,5R-Isomer Calcium Salt; (3S,5R,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Calcium Salt. Grade: > 95%. CAS No. 254452-88-5. Molecular formula: C25H23FNO4.1/2Ca. Mole weight: 440.86.
(3S,5R)-Rosuvastatin Methyl Ester
An impurity of Rosuvastatin.Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Synonyms: (3S,5R)-Rosuvastatin Methyl Ester. Grade: > 95%. CAS No. 1112048-62-0. Molecular formula: C23H30FN3O6S. Mole weight: 495.57.
(3S,5R)-Rosuvastatin Sodium Salt
An impurity of Rosuvastatin.Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Grade: > 95%. Molecular formula: C22H27FN3O6S. Na. Mole weight: 503.53.
(3S,5R)-tert-Butyl Pitavastatin
A metabolite of Pitavastatin which is a chemically synthesized statin used for hypercholesterolaemia (elevated cholesterol) and for the prevention of cardiovascular disease. Grade: > 95%. Molecular formula: C29H32FNO4. Mole weight: 477.58.
(3S,5S)-1-Isopropyl-3,4,5-piperidinetriol
(3S,5S)-1-Isopropyl-3,4,5-piperidinetriol, a novel chemical entity, exhibits tremendous potential as a therapeutic agent in the management of numerous pathologies. With its distinctive molecular makeup, this compound precisely modulates intricate intracellular cascades implicated in the advancement of diverse ailments. Robust investigations have substantiated its commendable effectiveness against select malignancies, heart conditions, and neurodegenerative afflictions. Considering its multifaceted characteristics, this compound emerges as an auspicious avenue necessitating comprehensive scholarly inquiry and advancement within the biomedical domain. Molecular formula: C8H17NO3. Mole weight: 175.23.
(3S,5S)-1-Nonyl-3,4,5-piperidinetriol
(3S,5S)-1-Nonyl-3,4,5-piperidinetriol, an indispensable compound in the biomedical sector, demonstrates its prominence in the development of therapeutic medications targeting numerous ailments such as neurological disorders and cardiovascular afflictions. Its exceptional molecular composition not only enhances the potency of pharmaceuticals but also ameliorates patient prognosis. Synonyms: 3,4,5-Piperidinetriol, 1-nonyl-, (3S,5S)-. CAS No. 875766-14-6. Molecular formula: C14H29NO3. Mole weight: 259.39.
(3S,5S,2S,3R)-Posaconazole
(3S,5S,2S,3R)-Posaconazole is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: 4-(4-(4-(4-(((3S,5S)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluoro phenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2S,3R)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one. CAS No. 2243785-98-8. Molecular formula: C37H42F2N8O4. Mole weight: 700.79.
(3S,5S)-Atorvastatin sodium salt
Atorvastatin is an HMG-CoA reductase inhibitor (IC50 = 154 nM) that is effective against hypercholesterolemia and certain dyslipidemias. Synonyms: 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid, monosodium salt; 3S,5S-Atorvastatin Sodium; sodium (3S,5S)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate. Grade: ≥98%. CAS No. 1428118-38-0. Molecular formula: C33H34FN2O5·Na. Mole weight: 580.6.
(3S, 5S)-Dihydroxy Simvastatin
An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: Butanoic acid, 2,?2-dimethyl-, 1,?2,?3,?4,?6,?7,?8,?8a-octahydro-4,?6-dihydroxy-3,?7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)?ethyl]?-1-naphthalenyl ester, [1S-[1α,?3α,?4β,?6α,?7β,?8β(2S*,?4S*)?,?8aβ]?]?- (9CI). Grade: > 95%. CAS No. 159143-77-8. Molecular formula: C25H40O7. Mole weight: 452.58.
(3S,5S)-Fluvastatin Sodium Salt
(3S,5S)-Fluvastatin Sodium Salt is an analogue of Fluvastatin (F601250). Synonyms: (S,S)-Fluvastatin Sodium Salt; [S-[R*,R*-(E)]]-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic Acid Monosodium Salt. Grade: > 95%. CAS No. 194935-01-8. Molecular formula: C24H25FNO4Na. Mole weight: 433.46.
(3S,5S)-Pitavastatin Calcium Salt
A metabolite of Pitavastatin which has a potent cholesterol-lowering action. Synonyms: 3-Epi-NK-104; Pitavastatin 3S,5S-Isomer Calcium Salt; (3S,5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Calcium Salt. Grade: > 95%. CAS No. 254452-92-1. Molecular formula: C25H23FNO4.1/2Ca. Mole weight: 440.5.
(3S,5S) Rosuvastatin Calcium Salt
An impurity of Rosuvastatin.Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Grade: > 95%. Molecular formula: C44H54F2N6O12S2. Ca. Mole weight: 1001.16.
(3S,5S)-Rosuvastatin Methyl Ester
An impurity of Rosuvastatin.Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Grade: > 95%. Molecular formula: C23H30FN3O6S. Mole weight: 495.57.
(3S,5S)-Rosuvastatin Sodium Salt
An impurity of Rosuvastatin salt.Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Synonyms: Rosuvastatin (3S,5S)-Isomer Sodium ; (3S, 5S)-Rosuvastatin Sodium ; Enantiomer of (3R,5R)-Rosuvastatin Sodium ; (3S,5S,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl (methyl sulfonyl) amino]-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic acid sodium salt. Grade: > 95%. Molecular formula: C22H27FN3O6S. Na. Mole weight: 503.53.
It is an impurity of paricalcitol, an analogue of vitamin D2. Paricalcitol is a medication used for the treatment of secondary hyperparathyroidism. Synonyms: Paricalcitol Impurity J. CAS No. 1192803-39-6. Molecular formula: C39H72O3Si2. Mole weight: 645.16.
An impurity of cyclosporin. Cyclosporin is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Molecular formula: C62H111N11O12. Mole weight: 1202.64.
(3S,8R,13R,18S)-1,20-Bis(1,1-dimethylethoxy)-1,6,15,20-tetraoxo-10,11-dithia-2,7,14,19-tetraazaeicosane-3,8,13,18-tetracarboxylic Acid 3,8,13,18-Tetrakis(1,1-dimethylethyl) Ester is an intermediate in the synthesis of L-γ-Glutamyl-(S)-Allyl-Cysteine, which is an extract from garlic used in the production of inflammatory mediators. Synonyms: (6S,11R,16R,21S)-Tetra-tert-butyl 2,2,25,25-Tetramethyl-4,9,18,23-tetraoxo-3,24-dioxa-13,14-dithia-5,10,17,22-tetraazahexacosane-6,11,16,21-tetracarboxylate; 10,11-Dithia-2,7,14,19-tetraazaeicosane-3,8,13,18-tetracarboxylic acid, 1,20-bis(1,1-dimethylethoxy)-1,6,15,20-tetraoxo-, 3,8,13,18-tetrakis(1,1-dimethylethyl) ester, (3S,8R,13R,18S)-; Tetrakis(2-methyl-2-propanyl) (6S,11R,16R,21S)-2,2,25,25-tetramethyl-4,9,18,23-tetraoxo-3,24-dioxa-13,14-dithia-5,10,17,22-tetraazahexacosane-6,11,16,21-tetracarboxylate. CAS No. 2112809-05-7. Molecular formula: C42H74N4O14S2. Mole weight: 923.18.
(3S)-Aminoquinuclidine Dihydrochloride
(3S)-Aminoquinuclidine Dihydrochloride is an intermediate in the synthesis of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Uses: Palonosetron intermediate. Synonyms: (S)-quinuclidin-3-amine dihydrochloride; (3S)-1-Azabicyclo[2.2.2]octan-3-amine Hydrochloride (1:2); (3S)-3-Amino-1-azabicyclo[2.2.2]octane Dihydrochloride; (3S)-quinuclidin-3-amine Dihydrochloride; 1-Azabicyclo[2.2.2]octan-3-amine, (3S)-, hydrochloride (1:2). Grade: ≥95%. CAS No. 119904-90-4. Molecular formula: C7H16Cl2N2. Mole weight: 199.12.
(3'S)-ent-Ezetimibe
A stereoisomer of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L9) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: S,S,R-Ezetimibe; (3S,4R)-1-(4-Fluorophenyl)-3-[(S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one; (3S,4R)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone; EZTRC-10 (SSR Isomer); Ezetimibe (3S,4R,3'S)-Isomer; (3S,4R,3'S)-Ezetimibe; Ezetimibe (SSR)-Isomer. Grade: >95%. CAS No. 1593543-00-0. Molecular formula: C24H21F2NO3. Mole weight: 409.44.
(3S)-Hydroxperoxy Simvastatin
An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: Butanoic acid, 2,?2-dimethyl-, (1S,?3S,?7S,?8S,?8aR)?-1,?2,?3,?7,?8,?8a-hexahydro-3-hydroperoxy-3,?7-dimethyl-8-[2-[(2R,?4R)?-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]?ethyl]?-1-naphthalenyl ester. Grade: > 95%. CAS No. 1092716-44-3. Molecular formula: C25H38O7. Mole weight: 450.57.
(3S)-N-[[(1S)-1,2,3,4-Tetrahydro-1-naphthalenyl]methyl]-1-azabicyclo[2.2.2]octan-3-amine is an intermediate of Palonosetron. Palonosetron (INN, trade name Aloxi) is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Uses: Palonosetron intermediate. Synonyms: [S-(R*,R*)]-N-[(1,2,3,4-Tetrahydro-1-naphthalenyl)methyl]-1-azabicyclo[2.2.2]octan-3-amine; (S)-N-(((S)-1,2,3,4-tetrahydronaphthalen-1-yl)methyl)quinuclidin-3-amine; Palonosetron Impurity 5. Grade: ≥95%. CAS No. 177793-80-5. Molecular formula: C18H26N2. Mole weight: 270.41.
(3S)-N-Methyl-γ-(1-naphthalenyloxy)-3-thiophenepropanamine is an impurity of Duloxetine, which is a serotonin-norepinephrine reuptake inhibitor used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, neuropathic pain and central sensitization. Synonyms: DLX-ISO 3; Duloxetine EP Impurity F; (γS)-N-Methyl-γ-(1-naphthalenyloxy)-3-thiophenepropanamine; (3S)-N-Methyl-3-(1-naphthyloxy)-3-(3-thienyl)-1-propanamine; 3-Thiophenepropanamine, N-methyl-γ-(1-naphthalenyloxy)-, (γS)-; (S)-N-Methyl-3-(naphthalen-1-yloxy)-3-(thiophen-3-yl)propan-1-amine. Grade: ≥95%. CAS No. 959392-22-4. Molecular formula: C18H19NOS. Mole weight: 297.41.
(3S)-Ondansetron
(3S)-Ondansetron is a highly effective antiemetic compound commonly used to study nausea and vomiting caused by chemotherapy, radiotherapy and surgery. It acts by blocking serotonin receptors in the brain and gastrointestinal tract, thereby preventing the initiation of vomiting signals. Synonyms: (3S)-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-2,3,4,9-tetrahydro-1H-carbazol-4-one; S-Ondansetron; (+)-Ondansetron; Ondansetron (base and/or unspecified salts); 4H-Carbazol-4-one, 1,2,3,9-tetrahydro-9-methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-, (3S)-. Grade: 95%. CAS No. 99614-58-1. Molecular formula: C18H19N3O. Mole weight: 293.36.
(3Z)-17-Desacetyl Norgestimate
(3Z)-17-Desacetyl Norgestimate is a metabolite of Norgestimate, which is a progestin medication used in birth control pills for women and in menopausal hormone therapy. Uses: Contraceptive agents, hormonal. Synonyms: syn-Norelgestromin; Z-17-Deacetylnorgestimate; (8R,9S,10R,13S,14S,17R,Z)-13-Ethyl-17-ethynyl-17-hydroxy-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one Oxime; (17α)-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one Oxime; 17-Deacetylnorgestimate; 18-Methylnorethindrone oxime; BRN 4202099; D-Norgestrel 3-Oxime; Levonorgestrel 3-Oxime; RWJ 10553; Norelgestromin. Grade: ≥95%. CAS No. 74183-54-3. Molecular formula: C21H29NO2. Mole weight: 327.46.
An impurity of Nintedanib, a receptor tyrosine kinase (RTK) inhibitor that binds to vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Nintedanib is used as a medication for the treatment of idiopathic pulmonary fibrosis. Synonyms: Nintedanib Impurity U. Grade: ≥95%. CAS No. 2102162-79-6. Molecular formula: C22H22N2O3. Mole weight: 362.42.
An impurity of Methotrexate, an antimetabolite and immunosuppressant used in chemotherapy and auto-immune diseases. Grade: 95%. CAS No. 1217459-90-9. Molecular formula: C19H22N8O6. Mole weight: 458.4.
An impurity of Amiodarone, an antiarrhythmic medication used to treat ventricular tachycardia or ventricular fibrillation. Synonyms: (4-(2-(Diethylamino)ethoxy)-3-iodophenyl)(2-(1-hydroxybutyl)benzofuran-3-yl)methanone. Grade: 95%. CAS No. 318267-28-6. Molecular formula: C25H30INO4. Mole weight: 535.41.
[4-(4-Phenylpiperazin-1-yl)oxan-4-yl]methanamine is a partial agonist of serotonin and dopamine receptors and has potential as a candidate for the treatment of psychiatric disorders such as depression and schizophrenia. Synonyms: (4-(4-Phenylpiperazin-1-yl)tetrahydro-2H-pyran-4-yl)methanamine; 2H-Pyran-4-methanamine, tetrahydro-4-(4-phenyl-1-piperazinyl)-; Tetrahydro-4-(4-phenyl-1-piperazinyl)-2H-pyran-4-methanamine; C-[4-(4-Phenylpiperazin-1-yl)tetrahydropyran-4-yl]methylamine; 1-[4-(4-phenylpiperazin-1-yl)oxan-4-yl]methanamine. Grade: 95%. CAS No. 1157013-41-6. Molecular formula: C16H25N3O. Mole weight: 275.39.
(4,9-13C2, 7-15N) Adenosine-3',5'-cyclic Monophosphate is the isotope labelled analog of Adenosine-3',5'-cyclic Monophosphate, which is an Adenosine derivative useful as an anticancer agent. Synonyms: Adenosine Cyclic-13C2,15N 3',5'-(Hydrogen Phosphate); 3',5'-AMP-13C2,15N; Adenosine-13C2,15N 3',5'-Phosphoric Acid; Cyclic 3',5'-AMP-13C2,15N; Cyclic 3',5'-Adenosine-13C2,15N Monophosphate; Cyclic AMP-13C2,15N; cAMP-13C2,15N. Molecular formula: C8[13C]2H12N4[15N]O6P. Mole weight: 332.18.
(4α,?5α)?-Formestane
(4α,?5α)?-Formestane is an isomer of Formestane. Formestane is a type I, steroidal, selective aromatase inhibitor that is used in the treatment of estrogen receptor-positive breast cancer in postmenopausal women. Formestane is an analogue of androstenedione. It is also used to inhibit the estrogen production. Synonyms: 4-Hydroxyandrostane-3,17-dione; 4-hydroxy-10,13-dimethyl-2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthrene-3,17-dione. CAS No. 848-35-1. Molecular formula: C19H28O3. Mole weight: 304.43.
(4-Aminophenyl)methyl b-D-thiocellobiose
(4-Aminophenyl)methyl b-D-thiocellobiose, a remarkable biomedicine, exhibits its efficacy in the treatment of a myriad of diseases. Acting as an inhibitor for select enzymes implicated in disease progression, this extraordinary compound manifests its potential by selectively targeting and obstructing aberrant cellular proliferation, hence augmenting the therapeutic efficacy. Synonyms: APTC; (2S,3R,4S,5S,6R)-2-(((2R,3S,4R,5R,6S)-6-((4-Aminobenzyl)thio)-4,5-dihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol; (4-Aminophenyl)methyl 4-O-β-D-glucopyranosyl-1-thio-β-D-glucopyranoside; (4-Aminophenyl)methyl 4-O-β-D-glucopyranosyl-β-D-thioglucopyranoside. CAS No. 68636-49-7. Molecular formula: C19H29NO10S. Mole weight: 463.50.
(4aS,4bS,10aR,10bS,11S,12aS)-1,11-Dihydroxy-1-(hydroxymethyl)-10a,12a-dimethyl-4,4a,4b,5,6,10a,10b,11,12,12a-decahydrochrysene-2,8(1H,3H)-dione is a derivative of Prednisolone, which is a glucocorticoid and an anti-inflammatory drug used to treat central nervous system disorders. Molecular formula: C21H28O5. Mole weight: 360.44.
(4aS,4bS,10aR,10bS,11S,12aS)-2',11-Dihydroxy-10a,12a-dimethyl-4,4a,4b,5,6,10a,10b,11,12,12a-decahydro-2H-spiro[chrysene-1,4'-[1,3,2]dioxaphospholane]-2,8(3H)-dione 2'-Oxide is a derivative of Prednisolone, which is a glucocorticoid and an anti-inflammatory drug used to treat central nervous system disorders. Grade: 90%. Molecular formula: C21H27O7P. Mole weight: 422.41.
(4E,15E)-Bilirubin acyl-b-D-glucuronide
Bilirubin acyl-b-D-glucuronide, an amalgamation of monoglucuronides, serves as an indispensable tool within the biomedical realm, facilitating in-depth exploration of bilirubin metabolism and its associated ailments. Its profound significance lies in the elucidation of therapeutic agents and methodologies tailored to combat conditions such as jaundice, hepatic disorders, and impairments linked to the eradication of bilirubin. Synonyms: Bilirubin acyl-b-D-glucuronide (Mixture of monoglucuronides); 21H-Biline-8,12-dipropanoic acid, 2,17-diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-, α8-β-D-glucopyranuronosyl ester, (4E,15E)-; (4E,15E)-Bilirubin IXα acyl-β-D-glucuronide; E,E-bilirubin acyl-β-D-glucuronide; E,E-Bilirubin IXα acyl-β-D-glucuronide; Bilirubin acyl-b-D-glucuronide. CAS No. 874448-90-5. Molecular formula: C39H44N4O12. Mole weight: 760.79.
(4E)-SUN9221
A potent dual antagonist of α1-adrenergic receptor and 5-HT2 receptor. Synonyms: (4E)-SUN9221; (4E)-SUN 9221; (4E)-SUN-9221; (4E)-1-[4-[4-(4-fluorobenzoyl)piperidin-1-yl]butyl]-4-hydroxyimino-7-methyl-5,6-dihydropyrrolo[2,3-c]azepin-8-one. CAS No. 222318-55-0. Molecular formula: C25H31FN4O3. Mole weight: 454.54.
(4-ethylcarbamoyl-butyl)triphenylphosphonium bromide is one of bimatoprost impurities. Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Synonyms: Bimatoprost Impurity 7. Grade: ≥ 98%. CAS No. 1201226-16-5. Molecular formula: C25H29BrNOP. Mole weight: 470.38.
[4-Hydroxy-1-methyl-4-(2-thienyl)-3-piperidinyl]-2-thienylmethanone Hydrochloride is an impurity of Duloxetine, which is a serotonin-norepinephrine reuptake inhibitor used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, neuropathic pain and central sensitization. Synonyms: Methanone, [4-hydroxy-1-methyl-4-(2-thienyl)-3-piperidinyl]-2-thienyl-, monohydrochloride; Methanone, [4-hydroxy-1-methyl-4-(2-thienyl)-3-piperidinyl]-2-thienyl-, hydrochloride (1:1). CAS No. 494221-40-8. Molecular formula: C15H18ClNO2S2. Mole weight: 343.89.
[4-L-Glutamic acid]desmopressin
An impurity of Desmopressin. Desmopressin is a synthetic analogue of the hormone vasopressin, used to treat conditions such as central diabetes insipidus, nocturnal enuresis (bedwetting), and certain bleeding disorders like hemophilia A and von Willebrand disease. Synonyms: Mpr-Tyr-Phe-Glu-Asn-Cys-Pro-DArg-Gly-NH2(Mpr1&Cys6 bridge); Mpr-YFENCP-DArg-G-NH2(Mpr1&Cys6 bridge); Desmopressin EP Impurity B; deamino-Cys-Tyr-Phe-Glu-Asn-Cys-Pro-D-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); Deamino-cysteinyl-L-tyrosyl-L-phenylalanyl-L-alpha-glutamyl-L-asparagyl-L-cysteinyl-L-prolyl-D-arginyl-glycinamide (1->6)-disulfide; Glu4-Desmopressin; [Glu4]-Desmopressin; Glu(4)-Desmopressin; Glycinamide, N-(3-mercapto-1-oxopropyl)-L-tyrosyl-L-phenylalanyl-L-α-glutamyl-L-asparaginyl-L-cysteinyl-L-prolyl-D-arginyl-, cyclic (1→5)-disulfide; Mpa-L-tyrosyl-L-phenylalanyl-L-glutamyl-L-aspartyl-L-cysteinyl-L-prolyl-D-arginyl-glycinamide] (disulphide bridges between Mpa1-Cys6); [L-Glu(4)]-Desmopressin. Grade: ≥95%. Molecular formula: C46H63N13O13S2. Mole weight: 1070.21.
(4-Methoxyphenyl)methylbeta-D-glucopyranoside
(4-Methoxyphenyl)methylbeta-D-glucopyranoside is a key compound used in the biomedical industry for various applications. This product is primarily utilized in the development of pharmaceutical drugs targeting specific diseases, particularly those related to glucoside metabolism or associated with glucosidase deficiencies. Its unique chemical structure confers potential therapeutic benefits, making it an indispensable component in biomedical research and drug discovery processes. Synonyms: (4-Methoxyphenyl)methyl beta-D-glucopyranoside. Grade: 95%. CAS No. 81381-72-8. Molecular formula: C14H20O7. Mole weight: 300.30.