BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| (E)-2-(7-methoxy-3,4-dihydronaphthalen-1(2H)-ylidene)ethan-1-amine | (E)-2-(7-methoxy-3,4-dihydronaphthalen-1(2H)-ylidene)ethan-1-amine is an impurity of agomelatine, an atypical antidepressant used to treat major depressive disorder. Synonyms: (2E)-2-(7-Methoxy-3,4-dihydro-1(2H)-naphthalenylidene)ethanamine. CAS No. 1371535-54-4. Molecular formula: C13H17NO. Mole weight: 203.28. |  |
| (E)-2-Decenoic acid | trans-2-Decenoic Acid is isolated along with 10-hydroxy-trans-2-decenoic acid, a fatty acid unique to royal jelly.(E)-2-decanoic acid(trans-2-Decenoic Acid) and 10-hydroxy-trans-2-decenoic acid are both described to demonstrate estrogenic activity, where the fatty acids demonstrate inhibition of 17β-estradiol binding to estrogen receptor-β. Synonyms: trans-2-Decenoic acid. Grade: >98%. CAS No. 334-49-6. Molecular formula: C10H18O2. Mole weight: 170.25. | |
| (E)-2-ethoxy-1-methoxy-4-(2-(methylsulfonyl)vinyl)benzene | (E)-2-ethoxy-1-methoxy-4-(2-(methylsulfonyl)vinyl)benzene is an impurity of Apremilast, which is an oral phosphodiesterase 4 inhibitor used for treating psoriatic arthritis. Synonyms: 1831833-38-5; 2-Ethoxy-1-methoxy-4-(2-methylsulfonylethenyl)benzene; DS-018767. Grade: 95%. CAS No. 1831833-38-5. Molecular formula: C12H16O4S. Mole weight: 256.32. | |
| (E)-2-hydroxy-3-(phenyldiazenyl)benzoic acid | (E)-2-hydroxy-3-(phenyldiazenyl)benzoic acid is an impurity of mesalamine. Mesalamine is the active metabolite of Sulfasalazine. Synonyms: Mesalamine Impurity 06. Grade: ≥95%. CAS No. 136819-59-5. Molecular formula: C13H10N2O3. Mole weight: 242.23. | |
| (E)-2-hydroxy-4-(phenyldiazenyl)benzoic acid | (E)-2-hydroxy-4-(phenyldiazenyl)benzoic acid is an impurity of mesalamine. Mesalamine is the active metabolite of Sulfasalazine. Synonyms: Mesalamine Impurity 04. Grade: 99%. CAS No. 40038-46-8. Molecular formula: C13H10N2O3. Mole weight: 242.23. | |
| (E)-2-(phenyldiazenyl)phenol | (E)-2-(phenyldiazenyl)phenol is an impurity of mesalamine. Mesalamine is the active metabolite of Sulfasalazine. Synonyms: Benzolazophenol; hydroxyazobenzene; 1-(phenylazo)-2-hydroxybenzene; Azobenzen-2-ol; 2-[(E)-Phenylazo]phenol; Mesalamine Impurity 05. CAS No. 2362-57-4. Molecular formula: C12H10N2O. Mole weight: 198.22. | |
| (E)-2-(Trityloxyimino)-2-[2-(tritylamino)thiazol-4-yl]acetic Acid | (E)-2-(Trityloxyimino)-2-[2-(tritylamino)thiazol-4-yl]acetic Acid is an intermediate in the preparation of Cefdinir, which is a semi-synthetic and broad-spectrum antibiotic used for soft tissue infections and respiratory tract infections. Synonyms: (E)-α-[(Triphenylmethoxy)imino]-2-[(triphenylmethyl)amino]-4-thiazoleacetic Acid; [2-(Trityl-amino)-thiazol-4-yl]-[(E)-trityloxyimino]-acetic acid. Grade: ≥95%. CAS No. 69689-81-2. Molecular formula: C43H33N3O3S. Mole weight: 671.80. | |
| (E)-3-(1-Ethyl-3-(4-fluorophenyl)-1H-indol-2-yl)acrylaldehyde | An impurity of Fluvastatin. Fluvastatin is a statin medication primarily used to treat high cholesterol and reduce the risk of cardiovascular events. Synonyms: (E)-3-[1-Ethyl-3-(4-fluorophenyl)-1H-indol-2-yl]-2-propenal; 2-Propenal, 3-[1-ethyl-3-(4-fluorophenyl)-1H-indol-2-yl]-, (E)-; Fluvastatin Impurity 17. Grade: ≥95%. CAS No. 93937-37-2. Molecular formula: C19H16FNO. Mole weight: 293.33. | |
| (E)-3-(4-((1H-imidazol-1-yl)methyl)phenyl)-1-(1H-imidazol-1-yl)prop-2-en-1-one | (E)-3-(4-((1H-imidazol-1-yl)methyl)phenyl)-1-(1H-imidazol-1-yl)prop-2-en-1-one is an impurity of Ozagrel, an antiplatelet drug that acts as a thromboxane A2 synthesis inhibitor. Synonyms: (E)-3-(4-((1H-imidazol-1-yl)methyl)phenyl)-1-(1H-imidazol-1-yl)prop-2-en-1-one; 2452215-05-1. CAS No. 2452215-05-1. Molecular formula: C16H14N4O. Mole weight: 278.32. | |
| (E)-3-O-Methyl Entacapone | An impurity of Entacapone. Entacapone is a medication commonly used in combination with other medications for the treatment of Parkinson's disease. Synonyms: (2E)-2-Cyano-N,N-diethyl-3-(4-hydroxy-3-methoxy-5-nitrophenyl)-2-propenamide. Grade: > 95%. CAS No. 857629-78-8. Molecular formula: C15H17N3O5. Mole weight: 319.32. | |
| (E)-3-(phenyldiazenyl)benzoic acid | (E)-3-(phenyldiazenyl)benzoic acid is an impurity of mesalamine. Mesalamine is the active metabolite of Sulfasalazine. Synonyms: Benzoic acid, 3-(phenylazo)-; azobenzen-3-carboxylic acid; Mesalamine Impurity 02. CAS No. 14474-22-7. Molecular formula: C13H10N2O2. Mole weight: 226.23. | |
| (E)-3-(phenyldiazenyl)phenol | (E)-3-(phenyldiazenyl)phenol is an impurity of mesalamine. Mesalamine is the active metabolite of Sulfasalazine. Synonyms: 3-Hydroxy-azobenzol; Mesalamine Impurity 03. CAS No. 2437-11-8. Molecular formula: C12H10N2O. Mole weight: 198.22. | |
| (E)-4-(2-(1-(p-tolyl)ethylidene)hydrazinyl)benzenesulfonamide | An impurity of Celecoxib, which is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits COX-2. Synonyms: 4-(2-(1-(p-Tolyl)ethylidene)hydrazinyl)benzenesulfonamide; Celecoxib Impurity 7. CAS No. 1061214-06-9. Molecular formula: C15H17N3O2S. Mole weight: 303.38. | |
| (E)-4-(2-(2,5-Dioxopyrrolidin-1-yl)ethoxy)-4-oxobut-2-enoic acid | An impurity of Diroximel Fumarate. Diroximel Fumarate is a prodrug of monomethyl fumarate, used primarily to treat relapsing forms of multiple sclerosis (MS), including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease in adults and children aged 10 years and older. Synonyms: 2-Butenedioic acid (2E)-, 1-[2-(2,5-dioxo-1-pyrrolidinyl)ethyl] ester; 1-[2-(2,5-Dioxo-1-pyrrolidinyl)ethyl] (2E)-2-butenedioate; (2E)-4-[2-(2,5-Dioxopyrrolidin-1-yl)ethoxy]-4-oxobut-2-enoic acid; Diroximel Fumarate Impurity 1; Diroximel Acid. Grade: ≥95%. CAS No. 2101811-41-8. Molecular formula: C10H11NO6. Mole weight: 241.20. | |
| (E)-4-Acetoxy Tamoxifen | A derivative of Tamoxifen. Tamoxifen is a selective estrogen receptor modulator (SERM) widely used in breast cancer treatment and prevention, particularly for estrogen receptor-positive (ER+) tumors. It works by competitively blocking estrogen receptors in breast tissue, inhibiting cancer cell growth. Synonyms: Phenol, 4-[(1E)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]-, acetate (ester); (E)-4-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol 1-Acetate; 4-[(1E)-1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol; Phenol, 4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]-, acetate (ester), (E)-; Tamoxifen (E)-4-Acetoxy Impurity; Tamoxifen Citrate Impurity 14. Grade: ≥95%. CAS No. 76117-70-9. Molecular formula: C28H31NO3. Mole weight: 429.55. | |
| (E)-4-Hydroxycrotonoic Acid Ethyl Ester | (E)-4-Hydroxycrotonoic Acid Ethyl Ester is an intermediate used to prepare unusual amino acids that are potential Michael acceptor-based anti-plasmodium and anti-trypanosomal cysteine protease inhibitors. Synonyms: Ethyl trans-4-Hydroxy-2-butenoate; (2E)-4-Hydroxy-2-butenoic Acid Ethyl Ester; 2-Butenoic acid, 4-hydroxy-, ethyl ester, (2E)-. Grade: 95%. CAS No. 10080-68-9. Molecular formula: C6H10O3. Mole weight: 130.14. | |
| (E)-4-Hydroxy-N-desmethyl tamoxifen | Endoxifen E-isomer, an active metabolite of Tamoxifen, has strong ER binding ability, can block the growth of estrogen-stimulated breast cancer cells, and has the maximum inhibitory effect on the expression of estrogen responsive genes in ER pos. human breast cancer cell line. Synonyms: E-Endoxifen; Endoxifen (E-isomer); 4-[(1E)-1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol; Tamoxifen 4-Hydroxy N-Desmethyl trans-Isomer. Grade: 95%. CAS No. 114828-90-9. Molecular formula: C25H27NO2. Mole weight: 373.49. | |
| (E)-4-Hydroxytamoxifen | (E)-4-Hydroxytamoxifen, a metabolite of Tamoxifen and the less active isomer of (Z)-4-hydroxytamoxifen, is an estrogen receptor modulator. Uses: Antineoplastic agents. Synonyms: (E)-Afimoxifene; (E)-4-(1-(4-(2-(Dimethylamino)ethoxy)phenyl)-2-phenylbut-1-en-1-yl)phenol; 4-[(1E)-1-{4-[2-(Dimethylamino)ethoxy]phenyl}-2-phenyl-1-buten-1-yl]phenol. Grade: ≥95%. CAS No. 174592-47-3. Molecular formula: C26H29NO2. Mole weight: 387.51. | |
| (E)-(4S,6S)-8-Methyl-6-((S)-3-methyl-2-{(S)-2-[(5-methyl-isoxazole-3-carbonyl)-amino]-propionylamino}-butyrylamino)-5-oxo-4-((R)-2-oxo-pyrrolidin-3-ylmethyl)-non-2-enoic acid benzyl ester | A SARS-CoV inhibitor. Synonyms: Benzyl (E,4S)-4-[[(2S)-4-methyl-2-[[(2S)-3-methyl-2-[[(2S)-2-[(5-methyl-1,2-oxazole-3-carbonyl)amino]propanoyl]amino]butanoyl]amino]pentanoyl]amino]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate. Molecular formula: C35H48N6O8. Mole weight: 680.8. | |
| (E)-5-(2-Carbomethoxyvinyl)-2'-deoxyuridine | (E)-5-(2-Carbomethoxyvinyl)-2'-deoxyuridine is a synthetic nucleoside analogue and antiviral agent. This product primarily treats Hepatitis B virus infections by inhibiting the replication of the virus's genetic material within the host cells. Synonyms: (E)-5-(2-carbomethoxyvinyl)-2'-deoxyuridine; 86163-17-9; methyl (E)-3-[1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]prop-2-enoate; E-5-(2-Carbomethoxyvinyl)-2'-deoxyuridine; (E)-Methyl 3-(1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acrylate; SCHEMBL1172165; SCHEMBL1807058; CHEMBL3144377; RKTRMSPWWLPPAY-YJCWOPNRSA-N; MFCD01631044; CS-0459211; E-5-(2-Carbomethoxyvinyl)-2'-deoxy-D-uridine; (E)-3-[4-Hydroxy-1-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-2-oxo-1,2-dihydro-pyrimidin-5-yl]-acrylic acid methyl ester. Grade: ≥ 97%. CAS No. 86163-17-9. Molecular formula: C13H16N2O7. Mole weight: 312.28. | |
| (E)-5-(2-Carbomethoxyvinyl)uridine | (E)-5-(2-Carbomethoxyvinyl)uridine is a biomedical product used in the treatment of viral infections, specifically targeting RNA viruses. It exhibits antiviral activity by inhibiting viral replication and relieving symptoms caused by viral diseases such as hepatitis and influenza. Grade: ≥ 97%. CAS No. 58931-19-4. Molecular formula: C13H16N3O8. Mole weight: 328.28. | |
| (E)-5-(2-Carboxyvinyl)-2'-deoxyuridine | (E)-5-(2-Carboxyvinyl)-2'-deoxyuridine is a novel synthetic compound used in biomedical research for the treatment of viral infections, specifically HIV. This product interferes with the virus's ability to hijack host DNA, inhibiting replication and progression of the disease. Synonyms: (E)-5-(2-carboxyvinyl)-2'-deoxyuridine; 74131-06-9; E-5-(2-Carboxyvinyl)-2'-deoxyuridine; (E)-3-(1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acrylic acid; (E)-3-[1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]prop-2-enoic acid; SCHEMBL535680; SCHEMBL887786; YWQZUENVQOQEHJ-PIXDULNESA-N; AKOS015856199; (2E)-3-{1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl}prop-2-enoic acid; (E)-3-(1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acrylicacid. Grade: ≥ 97%. CAS No. 74131-06-9. Molecular formula: C12H14N2O7. Mole weight: 298.25. | |
| (E)-5-(2-Carboxyvinyl)-2'-deoxyuridineN-Hydroxysuccinimide Ester | (E)-5-(2-Carboxyvinyl)-2'-deoxyuridine N-Hydroxysuccinimide Ester is a chemical compound catalyzing the synthesis of nucleoside surrogates. Such surrogates manifest paramount application in deciphering and combating virulent infections and neoplastic diseases. Grade: ≥ 97%. CAS No. 869355-24-8. Molecular formula: C16H17N3O9. Mole weight: 395.30. | |
| (E)-5-(2-Carboxyvinyl)uridine | (E)-5-(2-Carboxyvinyl)uridine is a powerful biochemical agent generally used in research related to RNA metabolism and modification. It's especially instrumental in studying diseases related to RNA alterations, such as certain genetic disorders and cancers. Synonyms: (E)-3-(1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acrylic acid; 3-(1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acrylic acid. Grade: 95%. CAS No. 99394-52-2. Molecular formula: C12H14N2O8. Mole weight: 314.26. | |
| (E)-5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzylidene)thiazolidine-2,4-dione | (E)-5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzylidene)thiazolidine-2,4-dione is an impurity of Pioglitazone, a PPAR agonist that has antidiabetic activity in patients with type 2 diabetes mellitus. Synonyms: 2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methylene]-, (5E)-; (5E)-5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methylene]-2,4-thiazolidinedione; 2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methylene]-, (E)-. Grade: 98%. CAS No. 136401-70-2. Molecular formula: C19H18N2O3S. Mole weight: 354.42. | |
| (E)-5-((4-(((Carboxymethyl)amino)carbonyl)phenyl)azo)-2-hydroxybenzoic acid | (E)-5-((4-(((Carboxymethyl)amino)carbonyl)phenyl)azo)-2-hydroxybenzoic acid, a biomedical compound, exhibits immense promise instudying diverse ailments like cancer. Synonyms: Benzoic acid, 5-[[4-[[(carboxymethyl)amino]carbonyl]phenyl]azo]-2-hydroxy-, (E)-; (E)-p-((3-Carboxy-4-hydroxyphenyl)azo)hippuric acid; (E)-3-(2-(4-((carboxymethyl)carbamoyl)phenyl)hydrazono)-6-oxocyclohexa-1,4-diene-1-carboxylic acid. Grade: ≥95%. CAS No. 80573-03-1. Molecular formula: C16H13N3O6. Mole weight: 343.29. | |
| (E)-[6]-Dehydroparadol | (E)-[6]-Dehydroparadol is an oxidative metabolite of [6]-Shogaol and it is a potent Nrf2 activator. (E)-[6]-Dehydroparadol inhibits the growth and induces the apoptosis of human cancer cells. Synonyms: Dehydroparadol; 1-Decen-3-one, 1-(4-hydroxy-3-methoxyphenyl)-, (1E)-; (6)-Dehydroparadol. Grade: ≥95%. CAS No. 878006-06-5. Molecular formula: C17H24O3. Mole weight: 276.37. | |
| (E)-8-Methyl-6-nonenoic acid | (E)-8-Methyl-6-nonenoic acid is a thermal degradant of Capsaicin. Synonyms: 8-methylnonenoate; 8-Methyl-6-nonenoic acid; (E)-8-methylnon-6-enoic acid. Grade: >95%. CAS No. 59320-77-3. Molecular formula: C10H18O2. Mole weight: 170.25. | |
| (E)-9-Oxononyl4-((2S,3R,4R,5S)-3,4-dihydroxy-5-((3-hydroxy-4,5-dimethyltetrahydrofuran-2-yl)methyl)tetrahydro-2H-pyran-2-yl)-3-methylbut-2-enoate | 9-oxononyl (E)-4-((2S,3R,4R,5S)-3,4-dihydroxy-5-((3-hydroxy-4,5-dimethyltetrahydrofuran-2-yl)methyl)tetrahydro-2H-pyran-2-yl)-3-methylbut-2-enoate is an impurity of Mupirocin, which is a carboxylic acid bacteriostatic/bactericidal antibiotic. Synonyms: Mupirocin USP Impurity 4; 9-((E)-4-((2S,3R,4R,5S)-3,4-dihydroxy-5-((3-hydroxy-4,5-dimethyltetrahydrofuran-2-yl)methyl)tetrahydro-2H-pyran-2-yl)-3-methylbut-2-enoyloxy)nonanoic Acid. Grade: 98%. Molecular formula: C26H44O8. Mole weight: 484.62. | |
| (E)-Akt inhibitor-IV | (E)-Akt inhibitor-IV ((E)-AKTIV) is a PI3K-Akt inhibitor, with potent cytotoxic. AKT Inhibitor IV promotes hyperphosphorylation of Akt (Protein kinase B), decreases phosphorylation of Akt substrates, and inhibits FOXO1a nuclear export (IC50 = 625 nM in PTEN-null cells). Synonyms: 6-(2-Benzothiazolyl)-1-ethyl-2-[(1E)-2-(methylphenylamino)ethenyl]-3-phenyl-1H-benzimidazolium iodide. Grade: ≥98%. CAS No. 959841-49-7. Molecular formula: C31H27IN4S. Mole weight: 614.54. | |
| (E)-Cefdinir | Cefdinir impurity. The E-isomer of Cefdinir. Synonyms: (6R,7R)-7-[[(2E)-(2-Amino-4-thiazolyl)(hydroxyimino)acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid. Grade: > 95%. CAS No. 178601-88-2. Molecular formula: C14H13N5O5S2. Mole weight: 395.42. | |
| (E)-Cefdinir Trifluoroacetic Acid Salt Hydrate | (E)-Cefdinir Trifluoroacetic Acid Salt Hydrate is one of Cefdinir impurities. Cefdinir is a semi-synthetic, broad-spectrum antibiotic, used for soft tissue infections and respiratory tract infections. Synonyms: (6R,7R)-7-[[(2E)-(2-Amino-4-thiazolyl)(hydroxyimino)acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Trifluoroacetic Acid Salt Hydrate; Cefdinir EP Impurity R Trifluoroacetic Acid Salt Hydrate. Molecular formula: C14H13N5O5S2.xC2HF3O2.xH2O. Mole weight: 395.41 (free base). | |
| (E)-Cefetamet Pivoxil | The E-isomer of Cefetamet Pivoxil. Synonyms: (6R,7R)-7-[[(2E)-2-(2-Amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-methyl -8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid (2,2-Dimethyl-1- oxopropoxy)methyl Ester Hydrochloride. Grade: > 95%. CAS No. 1705612-82-3. Molecular formula: C20H25N5O7S2. Mole weight: 511.58. | |
| (E)-Cefodizime | an isomer of cefodizime. Uses: Anti-bacterial agents. Synonyms: Cefodizime; 69739-16-8; Cefodizima; Cefodizimum; CDZM; CEFODIZIME DISODIUM; HR 221; HR-221; Neucef; CHEBI:63214; HR 221 [AS SODIUM]; THR 221 [AS SODIUM]; Z31298J4HQ; Cefodizime (INN); (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; Modivid; S 77 1221 B [AS SODIUM]; THR-221; CEFODIZIME [INN]; 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-, (6R,7R)-; 7-[[(2E)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; Cefodizime Sodium [JAN]. Grade: > 95%. CAS No. 97180-26-2. Molecular formula: C20H20N6O7S4. Mole weight: 584.67. | |
| (E)-Ceftibuten | isomer of ceftibuten. Synonyms: [6R-[6α,7β(E)]]-7-[[2-(2-Amino-4-thiazolyl)-4-carboxy-1-oxo-2-butenyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Dihydrate. Grade: > 95%. CAS No. 97519-40-9. Molecular formula: C15H14N4O6S2. Mole weight: 410.43. | |
| (E)-Ceftriaxone | An impurity of Ceftriaxone, a cephalosporin antibiotic for the treatment of various bacterial infections. Uses: The e-isomer of ceftriaxone (c245000), a third-generation cephalosporin. Synonyms: (6R,7R)-7-[[(2E)-2-(2-Amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; Ro 15-2254; Ceftriaxone EP Impurity A; Ceftriaxone E-isomer. CAS No. 92143-31-2. Molecular formula: C18H18N8O7S3. Mole weight: 554.58. | |
| (E)-Cefuroxime axetil | (E)-Cefuroxime axetil is the (E)-isomer of cefuroxime axetil, a prodrug form of the second-generation cephalosporin antibiotic cefuroxime. The E configuration refers to the stereochemistry of the oxime group on the β-lactam core, which is in the trans orientation. This isomer is the therapeutically active form, contributing to its antibacterial efficacy. Cefuroxime axetil improves the oral bioavailability of cefuroxime by utilizing the acetoxyethyl ester as a prodrug, which is hydrolyzed in vivo to release the active drug. It acts by inhibiting bacterial cell wall synthesis via binding to penicillin-binding proteins (PBPs). This compound is effective against a wide range of Gram-positive and Gram-negative bacteria and is commonly used to treat respiratory tract infections, urinary tract infections, and skin infections. Synonyms: 1-Acetoxyethyl (6R,7R)-3-((carbamoyloxy)methyl)-7-((E)-2-(furan-2-yl)-2-(methoxyimino)acetamido)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; Cefuroxime Axetil E-Isomer Impurity 1; 1-(Acetyloxy)ethyl (6R,7R)-3-[[(aminocarbonyl)oxy]methyl]-7-[[(2E)-2-(2-furanyl)-2-(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-c. Grade: ≥95%. CAS No. 97232-96-7. Molecular formula: C20H22N4O10S. Mole weight: 510.47. | |
| (E,E)-6-α-Ionylidene-4-methylpyran-2-one | (E,E)-6-α-Ionylidene-4-methylpyran-2-one is a renowned chemical compound in the biomedical industry, aiding in effectively impeding the proliferation of specific malignant cells, thereby paving the way for its application as an anti-cancer medication. Furthermore, its multifaceted nature unveils outstanding anti-inflammatory attributes. Uses: Intermediate in the preparation of retinoic acid derivatives. Synonyms: (E,E)-4-Methyl-6-[2-methyl-4-(2,6,6-trimethyl-1-cyclohexen-1-yl)-1,3-butadienyl]-2H-pyran-2-one; 4-Methyl-6-[(1E,3E)-2-methyl-4-(2,6,6-trimethyl-1-cyclohexen-1-yl)-1,3-butadien-1-yl]-2H-pyran-2-one; 2H-Pyran-2-one, 4-methyl-6-[(1E,3E)-2-methyl-4-(2,6,6-trimethyl-1-cyclohexen-1-yl)-1,3-butadien-1-yl]-. Grade: ≥95%. CAS No. 87424-83-7. Molecular formula: C20H26O2. Mole weight: 298.42. | |
| (E,E)-Bis(2-hydroxybenzylidene)acetone | (E,E)-Bis(2-hydroxybenzylidene)acetone is a synthetic analogue of Curcumin, which is a phenolic pigment used as a herbal supplement, cosmetics ingredient, food flavoring, and food coloring. Synonyms: (1E,4E)-1,5-Bis(2-hydroxyphenyl)-1,4-pentadien-3-one; 2-HBA; (E,E)-1,5-Bis(2-hydroxyphenyl)-1,4-pentadien-3-one. Grade: ≥90%. CAS No. 131359-24-5. Molecular formula: C17H14O3. Mole weight: 266.29. | |
| (E, E, E)-2,4,6-Nonatrienal | (2E,4E,6E)-2,4,6-Nonatrienal is an unsaturated aldehyde that is a natural volatile constituent of aggregation pheromones produced by male flea beetles. Synonyms: (2E,4E,6E)-2,4,6-Nonatrienal; (E,E,E)-2,4,6-Nonatrienal; (E,E,E)-Nona-2,4,6-trienal; trans,trans,trans-Nona-2,4,6-trienal. Grade: > 95%. CAS No. 57018-53-8. Molecular formula: C9H12O. Mole weight: 136.2. | |
| (E,E)-Farnesyl Thioacetate | (E,E)-Farnesyl Thioacetate, an acetate derivative of (E,E)-Farnesyl Thiol, has inhibitory activity against human isoprenylcysteine carboxyl methyltransferase (Icmt) protein. Synonyms: Ethanethioic Acid S-[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrien-1-yl] Ester; Ethanethioic Acid S-[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrienyl] Ester; S-[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrien-1-yl] ethanethioate. Grade: ≥95%. CAS No. 340701-35-1. Molecular formula: C17H28OS. Mole weight: 280.47. | |
| (E)-Ethyl 4-(8-chloro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11(6H)-ylidene)-3,4-dihydropyridine-1(2H)-carboxylate | An impurity of Loratadine, which is a histamine H1 receptor antagonist used to treat allergies. Synonyms: 1(2H)-Pyridinecarboxylic acid, 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-3,4-dihydro-, ethyl ester, (4E)-; Dehydro Loratadine Isomer A (E-isomer); Ethyl (4E)-4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-3,4-dihydro-1(2H)-pyridinecarboxylate; Ethyl (E)-4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-3,4-dihydropyridine-1(2H)-carboxylate. Grade: 95%. CAS No. 2471971-95-4. Molecular formula: C22H21ClN2O2. Mole weight: 380.87. | |
| (E)-FeCP-oxindole | (E)-FeCP-oxindole is a human vascular endothelial cell growth factor receptor 2 (VEGFR-2) inhibitor (IC50 = 214 nM). (E)-FeCP-oxindole exhibits anticancer activity (IC50< 1 μM against B16 murine melanoma lines). Synonyms: (E)-3-Ferrocenylmethylidene-1,3-dihydro-2H-indol-2-one. CAS No. 884338-18-5. Molecular formula: C19H15FeNO. Mole weight: 329.17. | |
| (E)-GABAB receptor antagonist 1 | (E)-GABAB receptor antagonist 1, a trans-GABAB receptor antagonist 1, reduces the maximum effect of agonist GABA-induced IP3 (inositol trisphosphate) production (IC50 = 37.9 μM) in HEK293 cells overexpressing GABAB receptors and Gqi9 proteins without altering EC50. Synonyms: 3-Butenoic acid, 4-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-2-oxo-, (3E)-; (3E)-4-(3,5-di-tert-butyl-4-hydroxyphenyl)-2-oxobut-3-enoic acid. Grade: ≥95%. CAS No. 1611483-29-4. Molecular formula: C18H24O4. Mole weight: 304.38. | |
| (E)-KPT330 | (E)-Kpt-330 is an E-isomer of Kpt-330, also known as Selinexor, which is an orally available inhibitor of CRM1 with potential antineoplastic activity. Synonyms: (E)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-N'-(pyrazin-2-yl)acrylohydrazide; Selinexor trans-isomer; KPT-330, (E)-; UNII-MVY2AE6R24; MVY2AE6R24; KPT330,(E)-; 2-Propenoic acid, 3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-, 2-(2-pyrazinyl)hydrazide, (2E)-; 1421923-86-5 (E-isomer); KPT330Selinexor; O=C(NNC1=NC=CN=C1)/C=C/N2N=C(C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)N=C2; 2-Propenoic acid, 3-[3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-, 2-(2-pyrazinyl)hydrazide, (2E)-; (E)-3-[3-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-triazol-1-yl]-N'-pyrazin-2-ylprop-2-enehydrazide. Grade: ≥95%. CAS No. 1421923-86-5. Molecular formula: C17H11F6N7O. Mole weight: 443.3. | |
| (E)-N-[2-(2,3-Dihydro-6-methoxy-1H-inden-1-ylidene)ethyl]propanamide | (E)-N-[2-(2,3-Dihydro-6-methoxy-1H-inden-1-ylidene)ethyl]propanamide is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Uses: Intermediate in the preparation of ramelteon. Synonyms: N-[(2E)-2-(2,3-Dihydro-6-methoxy-1H-inden-1-ylidene)ethyl]propanamide. Grade: >95%. CAS No. 196597-82-7. Molecular formula: C15H19NO2. Mole weight: 245.32. | |
| (E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-hydroxyquinazolin-6-yl)-4-(dimethylamino)but-2-enamide | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: Afatinib Impurity L. Grade: ≥95%. CAS No. 2223677-61-8. Molecular formula: C20H19ClFN5O2. Mole weight: 415.85. | |
| (E)-N'-(9-((2R,3R,4R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-((tert-butyldimethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-N,N-dimethylformimidamide | (E)-N'-(9-((2R,3R,4R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-((tert-butyldimethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-N,N-dimethylformimidamide, a novel molecule with potential applications in cancer therapy, has been shown to act by selectively inhibiting certain proteins critical to cancer cell proliferation and survival. Studies performed in preclinical models demonstrated promising results, and efforts to further develop this compound are currently underway. Defining a precise mechanism of action will require more detailed studies of this complex therapeutic candidate. Synonyms: Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-N-[(dimethylamino)methylene]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-, (4ξ)-; (4ξ)-5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-N-[(dimethylamino)methylen]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]guanosine. Grade: 98%. Molecular formula: C40H50N6O7Si. Mole weight: 754.95. | |
| (E)-N'-(9-((2R,3R,4R,5R)-3-((tert-Butyldimethylsilyl)oxy)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-N,N-dimethylformimidamide | (E)-N'-(9-((2R,3R,4R,5R)-3-((tert-Butyldimethylsilyl)oxy)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-N,N-dimethylformimidamide is a remarkable pharmaceutical compound that functions as a potent and selective inhibitor of DPP-4, a crucial regulator in glucose metabolism. This characteristic identifies it as a potential therapeutic candidate for treating type 2 diabetes, offering a new avenue of hope to those affected by the condition. Despite its complexity and formidable composition, this product demonstrates unparalleled efficacy and promises to make a significant impact in the field of diabetes care. Synonyms: CS-0046519; (E)-N'-(9-((2R,3R,4R,5R)-3-((tert-Butyldimethylsilyl)oxy)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-N,N-dimethylformimidamide. Molecular formula: C19H32N6O5Si. Mole weight: 452.58. | |
| (E)-N'-(9-((2R,3R,4R,5R)-4-(Bis(4-methoxyphenyl)(phenyl)methoxy)-3-((tert-butyldimethylsilyl)oxy)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-N,N-dimethylformimidamide | (E)-N'-(9-((2R,3R,4R,5R)-4-(Bis(4-methoxyphenyl)(phenyl)methoxy)-3-((tert-butyldimethylsilyl)oxy)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-N,N-dimethylformimidamide, a powerful anticancer drug, effectively targets cancer cells by disrupting DNA replication. By inhibiting DNA polymerase, it interrupts the essential process of cell division, thus making it an effective chemotherapy drug against various tumors. This compound displays immense potential as a potent antineoplastic agent and holds significant promise for advanced cancer treatment. Synonyms: (E)-N'-(9-((2R,3R,4R,5R)-4-(bis(4-methoxyphenyl)(phenyl)methoxy)-3-((tert-butyl Dimethylsilyl)oxy)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-N,N-dimethyl formamidine. Grade: 98%. Molecular formula: C40H50N6O7Si. Mole weight: 754.95. | |
| (E)-Nitrofural | (E)-Nitrofural is the E-isomer of Nitrofural, a topical antibiotic ointment that is effective against both Gram-positive and Gram-negative bacteria and can be used to treat trypanosomiasis. Synonyms: Hydrazinecarboxamide, 2-[(5-nitro-2-furanyl)methylene]-, (2E)-; (2E)-2-[(5-Nitro-2-furanyl)methylene]hydrazinecarboxamide; Hydrazinecarboxamide, 2-[(5-nitro-2-furanyl)methylene]-, (E)-; (E)-2-((5-nitrofuran-2-yl)methylene)hydrazine-1-carboxamide; (E)-Nitrofurazone. Grade: ≥90%. CAS No. 112574-44-4. Molecular formula: C6H6N4O4. Mole weight: 198.14. | |
| (E)-O-(2-Acetamido-2-deoxy-D-glucopyranosylidene)amino N-phenyl carbamate | (1E)-2-(Acetylamino)-2-deoxy-N-[[(phenylamino)carbonyl]oxy]-D-gluconimidic acid, δ-lactone stands as a remarkable biomedical innovation with promising prospects in combating malignant tumors and cancerous ailments. It manifests an extraordinary capacity to impede the proliferation of cancer cells while inducing programmed cell death, thus exhibiting substantial antitumor activity. Synonyms: D-Gluconimidic acid, 2-(acetylamino)-2-deoxy-N-[[(phenylamino)carbonyl]oxy]-, δ-lactone, (1E)-; (E)-PugNAc; (1E)-2-(Acetylamino)-2-deoxy-N-[[(phenylamino)carbonyl]oxy]-D-gluconimidic acid, δ-lactone; (E)-O-(2-Acetamido-2-deoxy-D-glucopyranosylidene)amino N-Phenylcarbamate; N-acetylglucosaminono-1,5-lactone O-(phenylcarbamoyl)oxime; O-(2-Acetamido-2-deoxy-D-glucopyranosylidene)amino N-phenyl carbamate. CAS No. 872611-16-0. Molecular formula: C15H19N3O7. Mole weight: 353.33. | |
| (E)-Olopatadine | (E)-Olopatadine is an isomer of Olopatadine, a histamine blocker and mast cell stabilizer. Synonyms: Olopatadine, (E)-; Olopatadine (E)-Isomer. CAS No. 113806-06-7. Molecular formula: C21H23NO3. Mole weight: 337.4. | |
| (E)-Olopatadine fumarate salt | An impurity of Olopatadine, which is a histamine blocker and mast cell stabilizer. Synonyms: Dibenz[b,e]oxepin-2-acetic acid, 11-[3-(dimethylamino)propylidene]-6,11-dihydro-, (11E)-, (2E)-2-butenedioate (1:1); Dibenz[b,e]oxepin-2-acetic acid, 11-[3-(dimethylamino)propylidene]-6,11-dihydro-, (E)-, (E)-2-butenedioate (1:1); (11E)-11-[3-(Dimethylamino)propylidene]-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid fumarate salt. Grade: ≥95%. CAS No. 113836-21-8. Molecular formula: C21H23NO3.C4H4O4. Mole weight: 453.49. | |
| (E)-Olopatadine Hydrochloride | (E)-Olopatadine Hydrochloride is an impurity of Olopatadine, a histamine blocker and mast cell stabilizer. Synonyms: 2-[(11E)-11-[3-(dimethylamino)propylidene]-6H-benzo[c][1]benzoxepin-2-yl]ethanoic acid hydrochloride; Olopatadine (E)-Isomer. CAS No. 949141-22-4. Molecular formula: C21H24ClNO3. Mole weight: 373.9. | |
| (E)-Ozagrel hydrochloride | Ozagrel HCl is a selective thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral ischaemia. Uses: Enzyme inhibitors. Synonyms: ozagrel hydrochloride; OKY-046 hydrochloride. Grade: >98%. CAS No. 78712-43-3. Molecular formula: C13H13ClN2O2. Mole weight: 264.71. | |
| (E)-PAC-1 | (E)-PAC-1 is the isomer of PAC-1, the first procaspase activating compound that selectively induces apoptosis, or cell suicide, in cancerous cells. Synonyms: 1-Piperazineacetic acid, 4-(phenylmethyl)-, (2E)-2-[[2-hydroxy-3-(2-propen-1-yl)phenyl]methylene]hydrazide; 4-(Phenylmethyl)-1-piperazineacetic acid (2E)-2-[[2-hydroxy-3-(2-propen-1-yl)phenyl]methylene]hydrazide; (E)-N'-(3-allyl-2-hydroxybenzylidene)-2-(4-benzylpiperazin-1-yl)acetohydrazide. Grade: 95%. CAS No. 1044929-62-5. Molecular formula: C23H28N4O2. Mole weight: 392.49. | |
| (E)-RPL-554 | (E)-RPL-554 is an isomer of RPL-554, a potent and selective PDE3/4 inhibitor for respiratory diseases, particularly in patients with asthma. Synonyms: Ensifentrine; N-(2-{(2E)-9,10-dimethoxy-4-oxo-2-[(2,4,6-trimethylphenyl)imino]-6,7-dihydro-2H-pyrimido[6,1-a]isoquinolin-3(4H)-yl}ethyl)urea; RPL 554; VMX 554. Grade: 98%. CAS No. 1884461-72-6. Molecular formula: C26H31N5O4. Mole weight: 477.56. | |
| (E)-(S)-4-[(S)-4-Methyl-2-((S)-3-methyl-2{(S)-2-[(5-methyl-isoxazole-3- carbonyl)-amino]-propionylamino}-butyrylamino)-pentanoylamino]-5-((S)-2- oxo-pyrrolidin-3-yl)-pent-2-enoic acid ethyl ester | A SARS-CoV Mpro inhibitor. Synonyms: ethyl (E,4S)-4-[[(2S)-4-methyl-2-[[(2S)-3-methyl-2-[[(2S)-2-[(5-methylisoxazole-3-carbonyl)amino]propanoyl]amino]butanoyl]amino]pentanoyl]amino]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate. Molecular formula: C30H46N6O8. Mole weight: 618.7. | |
| (E)-SIS3 | An E enantiomer of Smad3 Inhibitor SIS3, an inhibitor of SMAD3, which is a receptor-regulated intracellular protein that functions downstream of TGF-β as well as activin receptors and mediates their signaling. SIS3 plays an important role in cell proliferation, apoptosis, differentiation and formation of extracellular matrix. SIS3 is a cell-permeable pyrrolopyridine compound that selectively inhibits TGF-β1-dependent Smad3 phosphorylation and Smad3-mediated cellular signaling. SIS3 has been shown to reduce TGF-β1-induced type 1 procollagen expression and myofibroblast differentiation in normal dermal fibroblasts as well as scleroderma fibroblasts. Synonyms: SIS3; Smad3 inhibitor SIS3; (E)-1-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)prop-2-en-1-one. Grade: 98%. CAS No. 521985-36-4. Molecular formula: C28H27N3O3. Mole weight: 453.53. | |
| (E)-Tamoxifen | An impurity of Tamoxifen. Tamoxifen is a selective estrogen receptor modulator (SERM) widely used in breast cancer treatment and prevention, particularly for estrogen receptor-positive (ER+) tumors. It works by competitively blocking estrogen receptors in breast tissue, inhibiting cancer cell growth. Synonyms: Tamoxifen EP Impurity A; 2-[4-[(E)-1,2-Diphenylbut-1-en-1-yl]phenoxy]-N,N-dimethylethan-1-amine ((E)-isomer); cis-Tamoxifen; 2-[4-[(1E)-1,2-Diphenyl-1-buten-1-yl]phenoxy]-N,N-dimethyl-ethanamine; (E)-2-[p-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine; cis-N,N-Dimethyl-2-(p-(1,2-diphenyl-1-butenyl)phenoxy)ethylamine; cis-1-(p-(2-(N,N-Dimethylamino)ethoxy)phenyl)-1,2-diphenylbut-1-ene; Tamoxifen Citrate EP Impurity A; Tamoxifen Impurity A. Grade: >95%. CAS No. 13002-65-8. Molecular formula: C26H29NO. Mole weight: 371.53. | |
| (E)-Tetrachlorvinphos | It is an organophosphate cholinesterase inhibitor that is used as an insecticide. Synonyms: Phosphoric acid, (1E)-2-chloro-1-(2,4,5-trichlorophenyl)ethenyl dimethyl ester; (1E)-2-Chloro-1-(2,4,5-trichlorophenyl)ethenyl dimethyl phosphate; Phosphoric acid, 2-chloro-1-(2,4,5-trichlorophenyl)ethenyl dimethyl ester, (E)-; Phosphoric acid, 2-chloro-1-(2,4,5-trichlorophenyl)vinyl dimethyl ester, (E)-; SD 13462; trans-Tetrachlorvinphos. CAS No. 22350-76-1. Molecular formula: C10H9Cl4O4P. Mole weight: 365.96. | |
| (E,Z)-2-propyl-2-Pentenoic Acid | (E,Z)-2-propyl-2-Pentenoic acid is a bioactive metabolite of valproic acid that exhibits the same profile and potency of anticonvulsant activity in animal models as its parent compound without any observed teratogenicity and hepatotoxicity. Uses: Teratogens. Synonyms: 2-propyl-2-pentenoate; 2-propylpenten-2-oic acid; 2-ene-VPA; 2-en-valproic acid. Grade: ≥98%. CAS No. 60218-41-9. Molecular formula: C8H14O2. Mole weight: 142.2. | |
| (E/Z)-AG490 | (E/Z)-AG490 is a racemic compound of (E)-AG490 and (Z)-AG490 isomers. (E)-AG490 is a tyrosine kinase inhibitor that inhibits EGFR, Stat-3 and JAK2/3. Uses: A potent and specific inhibitor of the jak-2 tyrosine kinase. in acute lymphoblastic leukemia (all) cells which abundantly express jak-2, ag-490 dose-dependently inhibited dna synthesis, blocked cell growth and induced apoptosis. ag-490 does not signific. Synonyms: (E/Z)-Tyrphostin AG490; (E/Z)-Tyrphostin B42; 2-Cyano-3-(3,4-dihydroxyphenyl)-N-(phenylmethyl)-2-propenamide; alpha-Cyano-(3,4-dihydroxy)-N-benzylcinnamide; N-Benzyl-2-cyano-3-(3,4-dihydroxyphenyl)acrylamide; 2-Cyano-3-(3,4-dihydroxyphenyl)-N-(benzyl)-2-propenamide. Grade: 95%. CAS No. 134036-52-5. Molecular formula: C17H14N2O3. Mole weight: 294.30. | |
| (E/Z)-BCI | (E/Z)-BCI is an inhibitor of dual specific phosphatase 1/6 (DUSP1/DUSP6) and mitogen-activated protein kinase with EC50 of 13.3 μM and 8.0 μM for DUSP6 and DUSP1 in cells, respectively. Synonyms: BCI; NSC 150117; 2-benzylidene-3-(cyclohexylamino)-2,3-dihydro-1h-inden-1-one. CAS No. 15982-84-0. Molecular formula: C22H23NO. Mole weight: 317.42. | |
| (E/Z)-BIO-acetoxime | (E/Z)-BIO-acetoxime, a potent and selective GSK-3α/β inhibitor, with an IC50 of 10 nM, shows more than 200-fold selectivity over CDK5/p25, CDK2/cyclin A and CDK1/cyclin B with IC50s of 2.4, 4.3, 63 μM, respectively. Synonyms: GSK-3 Inhibitor X; 2H-Indol-2-one, 3-[3-[(acetyloxy)imino]-1,3-dihydro-2H-indol-2-ylidene]-6-bromo-1,3-dihydro-; [2-(6-bromo-2-oxo-2,3-dihydro-1H-indol-3-ylidene)-2H-indol-3-yl]amino acetate. Grade: ≥95%. CAS No. 740841-15-0. Molecular formula: C18H12BrN3O3. Mole weight: 398.21. | |
| (E/Z)-CP-724714 | (E/Z)-CP-724714 is a racemic compound of (E)-CP-724714 and (Z)-CP-724714 isomers. CP-724714 is a potent, selective and orally active ErbB2 (HER2) inhibitor with IC50 of 10 nM, and shows >640-fold selectivity against EGFR, InsR, IRG-1R, PDGFR, VEGFR2, Abl, Src, c-Met etc. Synonyms: 2-Methoxy-N-{3-[4-({3-methyl-4-[(6-methyl-3-pyridinyl)oxy]phenyl}amino)-6-quinazolinyl]-2-propen-1-yl}acetamide; Acetamide, 2-methoxy-N-[3-[4-[[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]phenyl]amino]-6-quinazolinyl]-2-propen-1-yl]-. Grade: >98%. CAS No. 537705-08-1. Molecular formula: C27H27N5O3. Mole weight: 469.53. | |
| (E/Z)-Curcumin | (E/Z)-Curcumin is an isomer of Curcumin, which is a phenolic pigment used as a herbal supplement, cosmetics ingredient, food flavoring, and food coloring. Synonyms: 1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxy-3-methoxyphenyl)-; 1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione; 1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadien-3,5-dione. Grade: ≥95%. CAS No. 94875-80-6. Molecular formula: C21H20O6. Mole weight: 368.38. | |
| (E/Z)-DMU2139 | (E/Z)-DMU2139 is a mixture of E- and Z-DMU2139, a potent and specific CYP1B1 inhibitor with IC50 of 9 nM and 795 nM for CYP1B1 and CYP1A1, respectively. Synonyms: 2-Propen-1-one, 1-(6-methoxy-2-naphthalenyl)-3-(3-pyridinyl)-. CAS No. 104890-70-2. Molecular formula: C19H15NO2. Mole weight: 289.33. | |
| (E/Z)-Endoxifen | One of the impurities of Tamoxifen, which is an estrogen response modifier as well as protein kinase C inhibitor. Synonyms: 4-Hydroxy-N-Desmethyl Tamoxifen; N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture); 4-[1-[4-[2-(Methylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol. Grade: > 95%. CAS No. 110025-28-0. Molecular formula: C25H27NO2. Mole weight: 373.50. | |
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