BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
An isomer of Etodolac. Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2. Uses: The r-enantiomer of etodolac (e933090). anti-inflammatory; analgesic. Synonyms: 2-[(1R)-1,8-diethyl-4,9-dihydro-3H-pyrano[3,4-b]indol-1-yl]acetic acid; 2-[(1R)-1,8-diethyl-4,9-dihydro-3H-pyrano[3,4-b]indol-1-yl]acetic acid. Grade: > 95 %. CAS No. 87226-41-3. Molecular formula: C17H21NO3. Mole weight: 287.35.
(R)-(-)-1-Aminoindane
An intermediate for Rasagiline Mesylate.Rasagiline is an irreversible inhibitor of monoamine oxidase-B. It can be used as a monotherapy to treat symptoms in early Parkinson's disease or as an adjunct therapy in more advanced cases. Synonyms: (1R)-2,3-dihydro-1H-inden-1-amine; (1R)-2,3-dihydro-1H-inden-1-amine. Grade: > 95 %. CAS No. 10277-74-4. Molecular formula: C9H11N. Mole weight: 133.19.
(R)-1-Benzyl-4-((5,6-dimethoxy-1-oxo-2,3-dihydro-1H-inden-2-yl)methyl)pyridin-1-ium is an intermediate in the synthesis of Donepezil, which is a highly specific reversible acetylcholinesterase (AChE) inhibitor used to treat moderate to severe Alzheimer's disease. Synonyms: Donepezil impurity; (2R)-1-Benzyl-4-[(5,6-dimethoxy-1-oxo-2,3-dihydro-1H-inden-2-yl)methyl]pyridinium; Pyridinium, 4-[(2,3-dihydro-5,6-dimethoxy-1-oxo-1H-inden-2-yl)methyl]-1-(phenylmethyl)-, (R)-; (R)-1-Benzyl-4-(5,6-dimethoxy-1-oxo-indan-2-ylmethyl)-pyridinium. Molecular formula: C24H24NO3?. Mole weight: 374.45.
(R)-1-glycylpyrrolidine-2-carbonitrile, hydrochloride (1:1) is an impurity of Vildagliptin. It is an oral anti-hyperglycemic agent (anti-diabetic drug) of the dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Synonyms: Vildagliptin Impurity 53 HCl. Molecular formula: C7H12N3OCl. Mole weight: 189.65.
(R)-1-(Naphthalen-1-yl)ethanamine hydrochloride
(R)-1-(Naphthalen-1-yl)ethanamine hydrochloride is an impurity of Cinacalcet, a pharmaceutical drug employed for treating hyperparathyroidism among individuals afflicted by chronic renal disorders and parathyroid carcinoma. Synonyms: (R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride; (R)-1-(Naphthalen-1-yl)ethanamine HCl. Grade: 95%. CAS No. 82572-04-1. Molecular formula: C12H14ClN. Mole weight: 207.70.
(R)-1-(Naphthalen-1-yl)-N-(3-(trifluoromethyl)benzyl)ethanamine, is an impurity of Cinacalcet, which is a drug that acts as a calcimimetic, and is used to treat secondary hyperparathyroidism (elevated parathyroid hormone levels). Synonyms: 1-Naphthalenemethanamine, alpha-methyl-N-[[3-(trifluoromethyl)phenyl]methyl]-, (alphaR)-. CAS No. 1229512-52-0. Molecular formula: C20H18F3N. Mole weight: 329.36.
(R)-1-(Naphthalen-1-yl)-N-(3-(trifluoromethyl)benzyl)ethanamine hydrochloride, is an impurity of Cinacalcet, which is a drug that acts as a calcimimetic, and is used to treat secondary hyperparathyroidism (elevated parathyroid hormone levels). Synonyms: (αR)-α-Methyl-N-[[3-(trifluoromethyl)phenyl]methyl]-1-naphthalenemethanamine Hydrochloride; Cinacalcet Impurity 18. CAS No. 1229225-42-6. Molecular formula: C20H19ClF3N. Mole weight: 365.82.
(R)-1-phenyl-1-((S)-pyrrolidin-2-yl)ethanol
An impurity of Bisphenol A which is a structural component in polycarbonate beverage bottles. Synonyms: (5-Benzylidene-4-oxo-2-thioxo-thiazolidin-3-yl)-acetic acid. CAS No. 1133388-12-1. Molecular formula: C12H17NO. Mole weight: 191.27.
An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Synonyms: Ibrutinib Impurity BZDYH. Grade: ≥95%. CAS No. 2031255-25-9. Molecular formula: C25H24N6O3. Mole weight: 456.51.
(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde (CAS# 15186-48-8 ) is a useful research chemical. Synonyms: (4R)-2,2-dimethyl-1,3-dioxolane-4-carbaldehyde. CAS No. 15186-48-8. Molecular formula: C6H10O3. Mole weight: 130.14.
(R)-2-(2-Oxopyrrolidin-1-yl)butyric acid
An impurity of Levetiracetam, a medication indicated for the treatment of epilepsy. Uses: Used for proteomics research; anti-convulsing drug. Synonyms: 1-Pyrrolidineacetic acid, α-ethyl-2-oxo-, (αR)-; (αR)-α-Ethyl-2-oxo-1-pyrrolidineacetic acid; 1-Pyrrolidineacetic acid, α-ethyl-2-oxo-, (R)-. Grade: ≥95%. CAS No. 103833-72-3. Molecular formula: C8H13NO3. Mole weight: 171.19.
An impurity of Cephalexin. Cephalexin increases the activity of superficial mucous cells and orifice mucous cells of gastric glands, and inhibits the activity of cervix mucous cells. Synonyms: Cefalexin impurity 02. CAS No. 860011-30-9. Molecular formula: C16H17N3O4S. Mole weight: 347.39.
(R)-(2,3-dimethyl-3-((triethylsilyl)oxy)butyl)diphenylphosphine oxide is an intermediate of paricalcitol, an analogue of vitamin D2. Paricalcitol is a medication used for the treatment of secondary hyperparathyroidism. Synonyms: Phosphine oxide, [(2R)-2,3-dimethyl-3-[(triethylsilyl)oxy]butyl]diphenyl-. CAS No. 1227926-70-6. Molecular formula: C24H37O2PSi. Mole weight: 416.60.
(R)-2-(3-Phenyl-3-(o-tolyloxy)propyl)isoindoline-1,3-dione is an intermediate in the synthesis of Atomoxetine, which is a selective norepinephrine (NE) reuptake inhibitor for the treatment of attention-deficit hyperactivity disorder (ADHD). Molecular formula: C24H21NO3. Mole weight: 371.43.
(R)-2-(4-(2-Hydroxy-3-(2-methoxyphenoxy)propyl)piperazin-1-yl)-N-(o-tolyl)acetamide is one of Ranolazine impurities. Ranolazine is an anti-ischemic agent which modulates myocardial metabolism. Molecular formula: C23H31N3O4. Mole weight: 413.51.
(R)-2-(4-(3-(2,6-Dimethoxyphenoxy)-2-hydroxypropyl)piperazin-1-yl)-N-(2,6-dimethylphenyl)acetamide is one of Ranolazine impurities. Ranolazine is an anti-ischemic agent which modulates myocardial metabolism. Molecular formula: C25H35N3O5. Mole weight: 457.56.
(R)-2-(4-(3-(2-Chloro-6-methoxyphenoxy)-2-hydroxypropyl)piperazin-1-yl)-N-(2,6-dimethylphenyl)acetamide is one of Ranolazine impurities. Ranolazine is an anti-ischemic agent which modulates myocardial metabolism. Molecular formula: C24H32ClN3O4. Mole weight: 461.98.
(R)-2-(4-(3-(2-(tert-Butoxy)phenoxy)-2-hydroxypropyl)piperazin-1-yl)-N-(2,6-dimethoxyphenyl)acetamide is one of Ranolazine impurities. Ranolazine is an anti-ischemic agent which modulates myocardial metabolism. Molecular formula: C27H39N3O6. Mole weight: 501.61.
An impurity of Mirabegron. Mirabegron (formerly YM-178, trade name Myrbetriq) is a drug for the treatment of overactive bladder. It was developed by Astellas Pharma and was approved in the United States in July 2012. Mirabegron activates the β3 adrenergic receptor in the detrusor muscle in the bladder, which leads to muscle relaxation and an increase in bladder capacity. Synonyms: (alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride; Mirabegron Impurity B (Hydrochloride Salt). CAS No. 521284-22-0. Molecular formula: C16H21ClN2O. Mole weight: 292.80.
An impurity of Mirabegron. Mirabegron (formerly YM-178, trade name Myrbetriq) is a drug for the treatment of overactive bladder. It was developed by Astellas Pharma and was approved in the United States in July 2012. Mirabegron activates the β3 adrenergic receptor in the detrusor muscle in the bladder, which leads to muscle relaxation and an increase in bladder capacity. Synonyms: (R)-2-((2-(4-Nitrophenyl)-ethyl)amino)-1-phenylethanol monohydrochloride; Mirabegron Impurity F (Hydrochloride Salt). CAS No. 521284-21-9. Molecular formula: C16H19ClN2O3. Mole weight: 322.78.
An impurity of Trelagliptin. Trelagliptin is a pharmaceutical drug used for the treatment of type 2 diabetes. Synonyms: 4-Fluorobenzonitrile, (R)-2-((6-(3-((3-(2-cyano-5-fluorobenzyl)-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)amino)piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-; Trelagliptin Impurity I. Grade: 99%. CAS No. 1917324-13-0. Molecular formula: C31H32F2N8O4. Mole weight: 614.61.
An impurity of Trelagliptin. Trelagliptin is a pharmaceutical drug used for the treatment of type 2 diabetes. Synonyms: Benzamide, 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-4-fluoro-; Trelagliptin Impurity R. Grade: >95%. CAS No. 1938080-44-4. Molecular formula: C18H22FN5O3. Mole weight: 375.40.
An impurity of Trelagliptin. Trelagliptin is a pharmaceutical drug used for the treatment of type 2 diabetes. Synonyms: Trelagliptin Impurity S. CAS No. 1917324-15-2. Molecular formula: C18H23FN4O4. Mole weight: 378.41.
(R)-2-((6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzamide is an impurity of alogliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor in the class of oral antidiabetic drugs. Synonyms: Alogliptin Impurity 14; Alogliptin Carbamoyl Impurity. CAS No. 1820685-30-0. Molecular formula: C18H23N5O3. Mole weight: 357.41.
(R)-2-(Acetylamino)-2-deoxy-α-D-glucopyranose 1-(Dihydrogen phosphate) 3-(3-Hydroxytetradecanoate) is an intermediate in synthesizing UDP-3-O[R-3-Hydroxymyristoyl]-N-acetylglucosamine Tris Salt, a lipid A precursor for Escherichia coli. Synonyms: (R)-(2R,3R,4R,5S,6R)-3-Acetamido-5-hydroxy-6-(hydroxymethyl)-2-(phosphonooxy)tetrahydro-2H-pyran-4-yl 3-hydroxytetradecanoate; α-D-Glucopyranose, 2-(acetylamino)-2-deoxy-, 1-(dihydrogen phosphate) 3-(3-hydroxytetradecanoate), (R)-. CAS No. 109304-40-7. Molecular formula: C22H42NO11P. Mole weight: 527.54.
One of the impurities of Glutathione. Glutathione (GSH) is an endogenous antioxidant which plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst. Synonyms: Glycine, N-(N-D-γ-glutamyl-L-cysteinyl)-; Glutathione Impurity 08. CAS No. 108457-42-7. Molecular formula: C10H17N3O6S. Mole weight: 307.32.
(R)-2-Aminobutanamide hydrochloride
An impurity of Levetiracetam, a medication indicated for the treatment of epilepsy. Synonyms: (R)-2-Aminobutanamide Monohydrochloride; Butanamide, 2-amino-, monohydrochloride, (R)-; Levetiracetam Impurity K. CAS No. 103765-03-3. Molecular formula: C4H11ClN2O. Mole weight: 138.59.
One of the impurities of Tirofiban, which has been found to be a glycoprotein IIb/IIIa inhibitor and could be used as an antiplatelet agent. Synonyms: Tirofiban Impurity 12. CAS No. 1346918-32-8. Molecular formula: C9H12N2O. Mole weight: 299.39.
(R)-2-Propenyl O-4,6-O-(phenylmethylene)-α-D-glucopyranosyl-(1→4)-O-α-D-glucopyranosyl-(1→4)-β-D-glucopyranoside can be used as an intermediate in the synthesis of 6-α-D-Glucopyranosyl Maltotriose. Sugar composition of sake. Synonyms: β-D-Glucopyranoside, 2-propenyl O-4,6-O-(phenylmethylene)-α-D-glucopyranosyl-(1→4)-O-α-D-glucopyranosyl-(1→4)-, (R)-. CAS No. 171411-99-7. Molecular formula: C28H40O16. Mole weight: 632.61.
An impurity of Elagolix sodium, a medication indicated for the treatment of moderate to severe pain associated with endometriosis. Synonyms: (R)-3-(2-Amino-2-phenylethyl)-5-(2-fluoro-3-methoxyphenyl)-1-[2-fluoro-6-(trifluoromethyl)benzyl]-6-methylpyrimidine-2,4(1H,3H)-dione. Grade: 95%. CAS No. 830346-50-4. Molecular formula: C28H24F5N3O3. Mole weight: 545.5.
One of the impurities of Tedizolid, which has been found to be an antibacterial agent and could be effective in the treatment of bacterial skin infections. Synonyms: 2-Oxazolidinone, 3-(2-bromo-5-fluorophenyl)-5-(hydroxymethyl)-, (5R)-; Tedizolid Impurity 49. CAS No. 2044710-49-6. Molecular formula: C10H9BrFNO3. Mole weight: 290.09.
An intermediate of Suzetrigine, which is an oral selective NaV1.8 pain signal inhibitor developed for the treatment of moderate-to-severe acute pain. Synonyms: 2(5H)-Furanone, 3-(3,4-difluoro-2-methoxyphenyl)-4,5-dimethyl-5-(trifluoromethyl)-, (5R)-; (5R)-3-(3,4-Difluoro-2-methoxyphenyl)-4,5-dimethyl-5-(trifluoromethyl)-2(5H)-furanone; VX-548 intermediate; Suzetrigine intermediate. Grade: ≥95%. CAS No. 2875066-35-4. Molecular formula: C14H11F5O3. Mole weight: 322.23.
One of the impurities of Tedizolid, which has been found to be an antibacterial agent and could be effective in the treatment of bacterial skin infections. Synonyms: Tedizolid phosphate impurity; 3-[3-fluoro-4-[6-(1-methyl-1H-tetrazol-5-yl)-3-pyridinyl]phenyl]-5-[(phosphonooxy)methyl]-, (5R)-. CAS No. 856867-56-6. Molecular formula: C17H16FN6O6P. Mole weight: 450.32.
One of the impurities of Tedizolid, which has been found to be an antibacterial agent and could be effective in the treatment of bacterial skin infections. Synonyms: Butanoic acid [(5R)-3-[3-fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]-2-oxo-5-oxazolidinyl]methyl ester; Tedizolid Impurity 27. CAS No. 1700656-54-7. Molecular formula: C21H21FN6O4. Mole weight: 440.43.
One of the impurities of Tedizolid, which has been found to be an antibacterial agent and could be effective in the treatment of bacterial skin infections. Synonyms: Tedizolid Impurity 34; 1,2-Propanediol, 3-[[3-fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]amino]-, 1-(dihydrogen phosphate), (2R)-. Grade: 95%. CAS No. 2095200-69-2. Molecular formula: C16H18FN6O5P. Mole weight: 424.32.
One of the impurities of Tedizolid, which has been found to be an antibacterial agent and could be effective in the treatment of bacterial skin infections. Synonyms: Tedizolid Impurity 03. CAS No. 2044709-71-7. Molecular formula: C16H17FN6O2. Mole weight: 344.34.
One of the impurities of Tedizolid, which has been found to be an antibacterial agent and could be effective in the treatment of bacterial skin infections. Synonyms: (5R)-3-(3-fluorophenyl)-5-(hydroxymethyl)-2-oxazolidinone; (5R)-3-(3-fluorophenyl)-5-(hydroxymethyl)-1,3-oxazolidin-2-one. Grade: 98 %. CAS No. 149524-42-5. Molecular formula: C10H10FNO3. Mole weight: 211.19.
(R)-3-(4-(5-bromo-2-chlorobenzyl)phenoxy)tetrahydrofuran is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: (3R)-3-[4-(5-Bromo-2-chlorobenzyl)phenoxy]tetrahydrofuran. CAS No. 915095-90-8. Molecular formula: C17H16BrClO2. Mole weight: 367.66.
One of the impurities of Tedizolid, which has been found to be an antibacterial agent and could be effective in the treatment of bacterial skin infections. Synonyms: Tedizolid Impurity 08; 2-Oxazolidinone, 3-[3-fluoro-4-[6-(2H-tetrazol-5-yl)-3-pyridinyl]phenyl]-5-(hydroxymethyl)-, (5R)-. CAS No. 1771765-84-4. Molecular formula: C16H13FN6O3. Mole weight: 356.31.
(R)-3-(4-Chlorophenyl)-4-hydroxybutyric Acid Sodium Salt
(R)-3-(4-Chlorophenyl)-4-hydroxybutyric Acid Sodium Salt is a metabolite of Baclofen, which is a specific GABA-B receptor agonist with muscle relaxant effect. Synonyms: Sodium (R)-3-(4-chlorophenyl)-4-hydroxybutanoate; (R)-4-Chloro-β-(hydroxymethyl)-benzenepropanoic Acid Sodium Salt; (R)-β-(p-Chlorophenyl)-γ-hydroxybutyric Acid Sodium Salt. Grade: 98%. CAS No. 1346617-22-8. Molecular formula: C10H10ClNaO3. Mole weight: 236.63.
(R)-3,4-DCPG
(R)-3,4-DCPG is an AMPA receptor antagonist with weak activity at NMDA receptors and no activity at kainate receptors. Synonyms: (R)-3,4-Dicarboxyphenylglycine; 4-[(1R)-1-Amino-2-hydroxy-2-oxoethyl]phthalic acid. Grade: ≥96% by HPLC. CAS No. 201730-10-1. Molecular formula: C10H9NO6. Mole weight: 239.18.
(R)-(3-(4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl methanesulfonate is an impurity of Linezolid, an oxazolidinone antimicrobial that is used to treat infections against gram-positive bacteria, especially those that are drug-resistant. Linezolid works by inhibiting bacterial protein synthesis. Synonyms: 2-Oxazolidinone, 5-[[(methylsulfonyl)oxy]methyl]-3-[4-(4-morpholinyl)phenyl]-, (5R)-; Linezolid Impurity 26. CAS No. 556801-09-3. Molecular formula: C15H20N2O6S. Mole weight: 356.39.
(R)-3-Amino-N-((R)-4-oxo-1-phenyl-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-2-yl)-4-(2,4,5-trifluorophenyl)butanamide is an impurity of Sitagliptin. Sitagliptin is an dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Molecular formula: C26H26F6N6O2. Mole weight: 568.51.
(R)-3-Amino-piperidine-2,6-dione
(R)-3-Amino-piperidine-2,6-dione is a remarkable pharmaceutical compound, renowned for its applications in the research against an array of debilitating afflictions encompassing cancer, diabetes and neurodegenerative disorders. Synonyms: D-2-Aminoglutarimide. Grade: >95%. CAS No. 673485-72-8. Molecular formula: C5H8N2O2. Mole weight: 128.13.
(R)-3-Carboxy-4-hydroxyphenylglycine
(R)-3-Carboxy-4-hydroxyphenylglycine has been found to be an antagonist of NMDA and AMPA/kainate receptor. Synonyms: D-(3-Carboxy-4-hydroxyphenyl)glycine; (αR)-α-Amino-3-carboxy-4-hydroxybenzeneacetic Acid. Grade: ≥98% by HPLC. CAS No. 13861-03-5. Molecular formula: C9H9NO5. Mole weight: 211.17.
(R)-3-Hydroxy Midostaurin
(R)-3-Hydroxy Midostaurin, a potent kinases inhibitor, is a major metabolite of midostaurin undergoing by the hepatic CYP3A4 enzyme. It has the potential for the treatment of acute myeloid leukemia (AML). Synonyms: (R)-CGP52421; Benzamide, N-((3R,9S,10R,11R,13R)-2,3,10,11,12,13-hexahydro-3-hydroxy-10-methoxy-9-methyl-1-oxo-9,13-epoxy-1H,9H-diindolo(1,2,3-gh:3',2',1'-lm)pyrrolo(3,4-j)(1,7)benzodiazonin-11-yl)-N-methyl-; 3-Hydroxy Midostaurin Epimer 2; CGP52421 Epimer 2. Grade: ≥95%. CAS No. 155848-20-7. Molecular formula: C35H30N4O5. Mole weight: 586.64.
(R)-(-)-3-Quinuclidinol
An impurity of Solifenacin. Solifenacin is a muscarinic M3 receptor antagonist for treating contraction of overactive bladder with associated problems such as increased urination frequency and urge incontinence. Synonyms: (R)-Quinuclidin-3-ol; R-(-)-Azabicyclo[2.2.2]octane-3-ol; (R)-3-Hydroxyquinuclidine; (3R)-Quinuclidin-3-ol. Grade: 96 %. CAS No. 25333-42-0. Molecular formula: C7H13NO. Mole weight: 127.18.
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L17) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: Ezetimibe Impurity O; 3-[(5R)-(4-Fluorophenyl)-5-hydroxypentanoyl]-(4R)-phenyl-1,3-oxazolidin-2-one. CAS No. 1612153-32-8. Molecular formula: C20H20FNO4. Mole weight: 357.38.
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L17) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: 3-[(5S)-(4-Fluorophenyl)-5-hydroxypentanoyl]-(4R)-phenyl-1,3-oxazolidin-2-one; Ezetimibe Impurity N. CAS No. 404874-94-8. Molecular formula: C20H20FNO4. Mole weight: 357.38.
An impurity of Trelagliptin. Trelagliptin is a pharmaceutical drug used for the treatment of type 2 diabetes. Synonyms: 4-Oxobutanoic Acid, (R)-4-((1-(3-(2-cyano-5-fluorobenzyl)-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidin-3-yl)amino)-; Trelagliptin Impurity 11. CAS No. 2087874-92-6. Molecular formula: C22H24FN5O5. Mole weight: 457.45.
(R)-4-((3R,5R,8S,9S,10R,13R,14S,17R,Z)-6-ethylidene-3-hydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a] phenanthren-17-yl)pentanoic acid is an impurity of obeticholic acid, which is used in the treatment of primary biliary cholangitis and various liver diseases. Synonyms: (E)-3-hydroxy-6-ethylidene-7-keto-5-cholan-24-oic acid. CAS No. 1516887-34-5. Molecular formula: C26H40O4. Mole weight: 416.60.
An impurity of Elagolix sodium, a medication indicated for the treatment of moderate to severe pain associated with endometriosis. Synonyms: 4,4'-((2-(5-(2-Fluoro-3-methoxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-3,6-dihydropyrimidin-1(2H)-yl)-1-phenylethyl)azanediyl)dibutyric acid, (R)-; Butanoic acid, 4,4'-(((1R)-2-(5-(2-fluoro-3-methoxyphenyl)-3-((2-fluoro-6-(trifluoromethyl)phenyl)methyl)-3,6-dihydro-4-methyl-2,6-dioxo-1(2H)-pyrimidinyl)-1-phenylethyl)imino)bis-. Grade: 95%. CAS No. 2409132-60-9. Molecular formula: C36H36F5N3O7. Mole weight: 717.7.
(R)-4-Carboxyphenylglycine
(R)-4-Carboxyphenylglycine has been found to be a moderately potent NMDA receptor antagonist. Synonyms: (R)-4-(Amino(Carboxy)Methyl)Benzoic Acid. Grade: ≥98% by HPLC. CAS No. 134052-68-9. Molecular formula: C9H9NO4. Mole weight: 195.17.
(R)-4-Ethyl-4-hydroxy-7,8-dihydro-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione is an intermediate of Exatecan, which is a DNA topoisomerase I inhibitor used to study cancer. Synonyms: (R)-Exatecan Intermediate 1; (4R)-4-ethyl-4-hydroxy-1H,3H,4H,6H,7H,8H,10H-pyrano[3,4-f]indolizine-3,6,10-trione; (4R)-4-Ethyl-4-hydroxy-7,8-dihydro-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione. Grade: ≥95%. CAS No. 110351-91-2. Molecular formula: C13H13NO5. Mole weight: 263.25.
An impurity of Brinzolamide, a potent carbonic anhydrase inhibitor used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Synonyms: (R)-4-HYDROXY-2-(3-METHOXYPROPYL)-3,4-DIHYDRO-2H-THIENO[3,2-E][1,2]THIAZINE-6-SULFONAMIDE 1,1-DIOXIDE; (4R)-4-hydroxy-2-(3-methoxypropyl)-1,1-dioxo-3,4-dihydrothieno[3,2-e]thiazine-6-sulfonamide; SCHEMBL3576264; (R)-4-HYDROXY-2-(3-METHOXYPROPYL)-3,4-DIHYDRO-2H-THIENO[3,2-E][1,2]THIAZINE-6-SULFONAMIDE1,1-DIOXIDE. CAS No. 165117-54-4. Molecular formula: C10H16N2O6S3. Mole weight: 356.44.
(R)-(+)-4-Isopropyl-5,5-diphenyl-2-oxazolidinone
(R)-(+)-4-Isopropyl-5,5-diphenyl-2-oxazolidinone is an oxazolidinone derivative for the stereoselective formation of C-C and C-X (X = O, N, Br, F, etc.) bonds. Synonyms: (R)-4-Isopropyl-5,5-diphenyl-2-oxazolidinone; 2-Oxazolidinone, 4-(1-methylethyl)-5,5-diphenyl-, (4R)-; (4R)-4-(1-Methylethyl)-5,5-diphenyl-2-oxazolidinone; 2-Oxazolidinone, 4-(1-methylethyl)-5,5-diphenyl-, (R)-; (R)-4-Isopropyl-5,5-diphenyloxazolidin-2-one; (4R)-(+)-4-Isopropyl-5,5-diphenyl-2-oxazolidinone. Grade: ≥95%. CAS No. 191090-32-1. Molecular formula: C18H19NO2. Mole weight: 281.35.
(R)-4-Nitrophenyl quinuclidin-3-yl carbonate
An impurity of Solifenacin. Solifenacin is a muscarinic M3 receptor antagonist for treating contraction of overactive bladder with associated problems such as increased urination frequency and urge incontinence. Synonyms: Carbonic acid, (3R)?-1-azabicyclo[2.2.2]?oct-3-yl 4-nitrophenyl ester; (R)-4-Nitrophenyl Quinuclidin-3-yl Carbonate. Grade: > 95%. CAS No. 1243274-81-8. Molecular formula: C14H16N2O5. Mole weight: 292.29.
(R)-(+)-4-tert-Butyl-2-oxazolidinone
(R)-(+)-4-tert-Butyl-2-oxazolidinone is an oxazolidinone derivative for the stereoselective formation of C-C and C-X (X = O, N, Br, F, etc.) bonds. Synonyms: (R)-4-(tert-Butyl)oxazolidin-2-one; (R)-(+)-4-tert-butyloxazolidin-2-one. Grade: 98%. CAS No. 142618-93-7. Molecular formula: C7H13NO2. Mole weight: 143.18.
An impurity of Elagolix sodium, a medication indicated for the treatment of moderate to severe pain associated with endometriosis. Synonyms: 2,4(1H,3H)-Pyrimidinedione, 5-(2-fluoro-3-methoxyphenyl)-1-((2-fluoro-6-(trifluoromethyl)phenyl)methyl)-6-methyl-3-((2R)-2-(2-oxo-1-pyrrolidinyl)-2-phenylethyl)-. Grade: 95%. CAS No. 2248628-93-3. Molecular formula: C32H28F5N3O4. Mole weight: 613.6.
One of the impurities of Tedizolid, which has been found to be an antibacterial agent and could be effective in the treatment of bacterial skin infections. Synonyms: Tedizolid Impurity 39; (5R)-3-[3-Fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-1-oxido-3-pyridinyl]phenyl]-5-[(phosphonooxy)methyl]-2-oxazolidinone. CAS No. 2095200-68-1. Molecular formula: C17H16FN6O7P. Mole weight: 466.32.
One of the impurities of Tedizolid, which has been found to be an antibacterial agent and could be effective in the treatment of bacterial skin infections. Synonyms: (5R)-3-[3-Fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-1-oxido-3-pyridinyl]phenyl]-5-(hydroxymethyl)-2-oxazolidinone; Tedizolid Impurity 40. CAS No. 2095100-93-7. Molecular formula: C17H15FN6O4. Mole weight: 386.34.
One of the impurities of Tedizolid, which has been found to be an antibacterial agent and could be effective in the treatment of bacterial skin infections. Synonyms: Tedizolid Impurity 24; 2-Pyridinecarbonitrile, 5-[2-fluoro-4-[(5R)-5-(hydroxymethyl)-2-oxo-3-oxazolidinyl]phenyl]-. CAS No. 1597428-07-3. Molecular formula: C16H12FN3O3. Mole weight: 313.28.
An impurity of Rivaroxaban. Rivaroxaban inhibits both free Factor Xa and Factor Xa bound in the prothrombinase complex. It is a highly selective direct Factor Xa inhibitor with oral bioavailability and rapid onset of action. Synonyms: Rivaroxaban Impurity 26; 2-Thiophenecarboxamide, 5-chloro-N-[4-(3-oxo-4-morpholinyl)phenyl]-N-[[(5R)-2-oxo-5-oxazolidinyl]methyl]-. CAS No. 1879903-65-7. Molecular formula: C19H18ClN3O5S. Mole weight: 435.88.
(R)-5-Hydroxylansoprazole is an impurity of lansoprazole, a proton pump inhibitor (PPI) used to treat the symptoms of gastroesophageal reflux disease (GERD). Synonyms: 5-Hydroxy dexlansoprazole. Grade: 95%. CAS No. 220609-28-9. Molecular formula: C16H14F3N3O3S. Mole weight: 385.36.