BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| (R)-(-)-Flindokalner | (R)-(-)-BMS 204352 is the less active R-(-)-enantiomer of BMS-204352, which is a positive modulator at neuronal Kv7 channels and calcium-activated K+ channels (BKCa) in HEK293 cells used as an anxiolytic agant. Uses: Anxiolytic agent. Synonyms: (R)-(-)-BMS 204352; (R)-(-)-BMS204352; (R)-(-)-BMS-204352; (3R)-3-(5-chloro-2-methoxyphenyl)-3-fluoro-6-(trifluoromethyl)-1H-indol-2-one. Grade: 98%. CAS No. 187523-36-0. Molecular formula: C16H10ClF4NO2. Mole weight: 359.7. |  |
| (R)-Flurbiprofen Axetil | (R)-Flurbiprofen Axetil is a widely utilized pharmaceutical compound in the biomedical sector, demonstrating its efficacy as a non-steroidal anti-inflammatory drug (NSAID). This remarkable compound plays a pivotal role in studying inflammation attributed to osteoarthritis, rheumatoid arthritis and an array of musculoskeletal ailments. Synonyms: [1,1'-Biphenyl]-4-acetic acid, 2-fluoro-α-methyl-, 1-(acetyloxy)ethyl ester, (αR)-; 1-(Acetyloxy)ethyl (αR)-2-fluoro-α-methyl[1,1'-biphenyl]-4-acetate; 1-Acetoxyethyl (2R)-2-(2-fluoro-[1,1'-biphenyl]-4-yl)propanoate. Grade: >95%. CAS No. 2375240-97-2. Molecular formula: C19H19FO4. Mole weight: 330.36. | |
| (R)-Funapide | (R)-Funapide is the less active R-enantiomer of Funapide, a sodium channel blocker, which can be used for the research of cancer. Synonyms: Funapide Enantiomer; (R)-TV 45070; (R)-XEN402. Grade: 98%. CAS No. 1259933-15-7. Molecular formula: C22H14F3NO5. Mole weight: 429.35. | |
| (R)-GNA-C(Bz)-phosphoramidite | (R)-GNA-C(Bz)-phosphoramidite, a chemical compound utilized within the biomedical industry as a crucial reagent for synthesizing oligonucleotides, enables the creation of modified oligonucleotides that may be directed towards the treatment of specific ailments, most notably cancer and viral infections. Its exceptional properties have rendered it a commonplace within research, catalyzing the development of innovative drug targets and treatment approaches. Synonyms: N-[1-[(2R)-3-[bis(4-methoxyphenyl)-phenylmethoxy]-2-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropyl]-2-oxopyrimidin-4-yl]benzamide. Grade: ≥95%. CAS No. 2023779-58-8. Molecular formula: C44H50N5O7P. Mole weight: 791.87. | |
| (R)-GNA-T phosphoramidite | (R)-GNA-T phosphoramidite is a chemical compound used in the synthesis of Glycol Nucleic Acids (GNA). It contains a thymine base (represented by ''T'') and is in the right-handed (R) stereoisomeric form. As a phosphoramidite, it is a key building block for constructing GNA sequences, similar to how DNA and RNA are synthesized. This compound plays a role in advancing research in synthetic biology, molecular engineering, and the development of new nucleic acid-based applications, including in gene therapy, diagnostics, and nanotechnology. Synonyms: (R)-G-T phosphoramidite; T-(R)-GNA phosphoramidite; (R)-GNA T amidite; (R)-GNA-T-phosphoramidite; DMT-T-(R)-GNA Phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, (1R)-2-[bis(4-methoxyphenyl)phenylmethoxy]-1-[(3,4-dihydro-5-methyl-2,4-dioxo-1(2H)-pyrimidinyl)methyl]ethyl 2-cyanoethyl ester; (1R)-2-[Bis(4-methoxyphenyl)phenylmethoxy]-1-[(3,4-dihydro-5-methyl-2,4-dioxo-1(2H)-pyrimidinyl)methyl]ethyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, (1R)-2-[bis(4-methoxyphenyl)phenylmethoxy]-1-[(3,4-dihydro-5-methyl-2,4-dioxo-1(2H)-pyrimidinyl)methyl]ethyl 2-cyanoethyl ester. Grade: ≥97%. CAS No. 851050-23-2. Molecular formula: C38H47N4O7P. Mole weight: 702.78. | |
| (R)-GNE-140 | (R)-GNE-140 is a potent lactate dehydrogenase A (LDHA) inhibitor (IC50s= 3 nM for LDHA and 5 nM for LDHB), with 18-fold more potent than S enantiomer. Synonyms: (2R)-5-(2-chlorophenyl)sulfanyl-4-hydroxy-2-(4-morpholin-4-ylphenyl)-2-thiophen-3-yl-1,3-dihydropyridin-6-one; GNE-140; GNE 140; GNE140. CAS No. 2003234-63-5. Molecular formula: C25H23ClN2O3S2. Mole weight: 499.04. | |
| (R)-GSK-3685032 | (R)-GSK-3685032 is the R-enantiomer of GSK-3685032, which is a non-time-dependent, non-covalent, first-in-class reversible and selective inhibitor of DNMT1, with an IC50 of 0.036 μM. GSK-3685032 induces robust loss of DNA methylation, transcriptional activation, and cancer cell growth inhibition. Synonyms: Benzeneacetamide, α-[[6-(4-amino-1-piperidinyl)-3,5-dicyano-4-ethyl-2-pyridinyl]thio]-, (αR)-. Grade: ≥98%. CAS No. 2170140-50-6. Molecular formula: C22H24N6OS. Mole weight: 420.53. | |
| (R)-Gyramide A hydrochloride | (R)-Gyramide A is a bacterial DNA gyrase inhibitor that disrupts supercoiling activity with an IC50 value of 3.3 μM. Synonyms: (R)-534F6; 5-fluoro-2-methyl-N-[(3R)-1-[[4-(1-methylethoxy)phenyl]methyl]-3-pyrrolidinyl]-benzenesulfonamide monohydrochloride. Grade: ≥95%. CAS No. 1793050-70-0. Molecular formula: C21H27FN2O3S·HCl. Mole weight: 443. | |
| (R)-(+)-HA-966 | (R)-(+)-HA-966 is a cell-permeable antagonist/partial agonist at the glycine site of the NMDA receptor. Synonyms: R(+)-HA-966; 1-Hydroxy-3-amino-pyrrolidine-2-one, (R)-; Tocris-0281; (R)-(+)-3-Amino-1-hydroxypyrrolidin-2-one. Grade: ≥98% by HPLC. CAS No. 123931-04-4. Molecular formula: C4H8N2O2. Mole weight: 116.12. | |
| (R)-Hydroxychloroquine | (R)-Hydroxychloroquine is the enantiomer of Hydroxychloroquine which is a medication used for the treatment of certain malaria. Hydroxychloroquine is efficiently inhibits SARS-CoV-2 infection in vitro. Synonyms: (R)-HCQ; (R)-(-)-Hydroxy Chloroquine Diphosphate; D-HCQ; Ethanol, 2-(((4R)-4-((7-chloro-4-quinolinyl)amino)pentyl)ethylamino)-. Grade: ≥98% (HPLC). CAS No. 137433-23-9. Molecular formula: C18H26ClN3O. Mole weight: 335.87. | |
| (R)-ICMT-IN-3 | (R)-ICMT-IN-3 is an inhibitor of ICMT (IC50=0.01 μM). Molecular formula: C22H29NO2. Mole weight: 339.47. | |
| (R)-JNJ-31020028 | (R)-JNJ-31020028 is a high affinity, selective brain penetrant antagonist of neuropeptide Y Y2 receptor (pIC50 values of 8.07, 8.22 and 8.21 for human, rat, and mouse Y2 receptor, respectively). Synonyms: (R)-N-(4-(4-(2-(diethylamino)-2-oxo-1-phenylethyl)piperazin-1-yl)-3-fluorophenyl)-2-(pyridin-3-yl)benzamide. CAS No. 1094873-17-2. Molecular formula: C34H36FN5O2. Mole weight: 565.68. | |
| (R)-(-)-JQ1 | (R)-(-)-JQ1 is the R-isomer and an inactive control of JQ1, a BET bromodomain inhibitor. Synonyms: (-)-JQ1; (-)-JQ 1; (-)-JQ-1; (R)-JQ1; (R)-(-)-tert-Butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate. Grade: >95%. CAS No. 1268524-71-5. Molecular formula: C23H25ClN4O2S. Mole weight: 456.989. | |
| (R)-Ketoprofen | Anti-inflammatory; analgesic. Synonyms: (αR)-3-Benzoyl-α-methylbenzeneacetic Acid; (-)-2-(3-Benzoylphenyl)propionic Acid; (-)-3-Benzoyl-α-methylbenzeneacetic Acid. Grade: > 95%. CAS No. 56105-81-8. Molecular formula: C16H14O3. Mole weight: 254.29. | |
| (R)-Ketoprofen b-D-glucuronide | (R)-Ketoprofen b-D-glucuronide, an indispensable pharmaceutical compound in the biomedical sector, serves as a remarkable remedy for alleviating pain and inflammation linked with conditions like arthritis and musculoskeletal disorders. Synonyms: β-D-Glucopyranuronic acid, 1-(3-benzoyl-α-methylbenzeneacetate), (R)-; (R)-Ketoprofen glucuronide; β-D-Glucopyranuronic acid, 1-[(αR)-3-benzoyl-α-methylbenzeneacetate]. CAS No. 140148-25-0. Molecular formula: C22H22O9. Mole weight: 430.40. | |
| (R)-KT109 | (R)-KT109 is the R isomer of the diacylglycerol lipase β (DAGLβ) inhibitor KT109. Synonyms: (4-[1,1'-biphenyl]-4-yl-1H-1,2,3-triazol-1-yl)[(2R)-2-(phenylmethyl)-1-piperidinyl]-methanone. Grade: ≥98%. CAS No. 2055172-60-4. Molecular formula: C27H26N4O. Mole weight: 422.52. | |
| (R)-Lanicemine | (R)-Lanicemine is the less active R-enantiomer of Lanicemine, which is a low-trapping NMDA channel blocker with a Ki of 0.56-2.1 μM for NMDA receptor, and IC50s of 4-7 and 6.4 μM in CHO and Xenopus oocyte cells, respectively. Synonyms: (R)-AZD6765; (1R)-1-Phenyl-2-(2-pyridinyl)ethanamine; 2-Pyridineethanamine, α-phenyl-, (αR)-; (R)-(-)-1-phenyl-2-(pyridin-2-yl)ethylamine. CAS No. 190581-71-6. Molecular formula: C13H14N2. Mole weight: 198.26. | |
| (R)-(+)-Lansoprazole | Dexlansoprazole is a proton pump inhibitor that is marketed by Takeda Pharmaceuticals for the treatment of erosive esophagitis and gastro-oesophageal reflux disease. Uses: Anti-ulcer agents. Synonyms: T 168390; TAK 390; T168390; TAK390; T-168390; TAK-390; Dexlansoprazole; Dexilant; Kapidex; TAK-390MR; TAK 390MR; TAK390MR. Grade: >98%. CAS No. 138530-94-6. Molecular formula: C16H14F3N3O2S. Mole weight: 369.36. | |
| (R)-Lercanidipine Hydrochloride | A dihydropyridine calcium channel blocker. Synonyms: (4R)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 2-[(3,3-Diphenylpropyl)methylamino]-1,1-dimethylethyl Methyl Ester Hydrochloride. Grade: > 95%. CAS No. 187731-34-6. Molecular formula: C36H42ClN3O6. Mole weight: 648.19. | |
| (R)-Levofloxacin | An impurity of Levofloxacin, which is as efficacious as or more efficacious than that with ciprofloxacin in systemic as well as pyelonephritis infections in mice. Synonyms: (3R)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid. Grade: > 95%. Molecular formula: C18H20FN3O4. Mole weight: 361.38. | |
| (R)-Licarbazepine Acetate | (R)-Licarbazepine Acetate is a promising antiepileptic drug structurally related to Carbamazepine which is used in treatment of pain associated with trigeminal neuralgia. Uses: A promising antiepileptic drug structurally related to carbamazepine and oxcarbazepine. Synonyms: (10R)-10-(Acetyloxy)-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide; (R)-(+)-10-Acetoxy-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide; BIA 2-059. CAS No. 186694-45-1. Molecular formula: C17H16N2O3. Mole weight: 296.32. | |
| (R)-Linezolid | (R)-Linezolid is an enatiomeric impurity of Linezolid, an antibiotic used for the treatment of infections caused by Gram-positive bacteria. Synonyms: N-{[(R)-3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl]methyl}acetamide; Linezolid R-Isomer; N-[[(5R)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide; Acetamide, N-[[(5R)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-; Linezolid R-isomer [USP-RS]; Linezolid Impurity R-isomer. Grade: ≥95%. CAS No. 872992-20-6. Molecular formula: C16H20FN3O4. Mole weight: 337.35. | |
| (R)-Lisinopril Sodium Salt | (R)-Lisinopril Sodium Salt is a salt of Lisinopril, a medication of the angiotensin-converting enzyme inhibitor class that is used to treat high blood pressure. Synonyms: (R)-1-[N2-(1-Carboxy-3-phenylpropyl)-L-lysyl]L-proline Sodium; N2-[(1R)-1-Carboxy-3-phenylpropyl)-L-lysyl]L-proline Sodium. Grade: 95%. CAS No. 1356019-70-9. Molecular formula: C21H31N3NaO5. Mole weight: 428.47. | |
| (R)-Lisofylline | LSF, a chiral metabolite of pentoxifylline, acts as a potent anti-inflammatory agent. (R)-LSF is the biologically active isomer of LSF. Uses: Adjuvants, immunologic. Synonyms: (-)-Lisofylline; (R)-LSF; 3,7-dihydro-1-[(5R)-5-hydroxyhexyl]-3,7-dimethyl-1H-purine-2,6-dione. Grade: ≥97%. CAS No. 100324-81-0. Molecular formula: C13H20N4O3. Mole weight: 280.3. | |
| (R)-Lopinavir Metabolite M-3/M-4 | (R)-Lopinavir Metabolite M-3/M-4 is an impurity of Lopinavir, a selective HIV protease inhibitor. Synonyms: 1(2H)-Pyrimidineacetamide, N-[(1S,3S,4S)-4-[[2-(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-4-hydroxy-α-(1-methylethyl)-2-oxo-, (αS,4R)-; (αS,4R)-N-[(1S,3S,4S)-4-[[2-(2,6-Dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-4-hydroxy-α-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetamide; 1(2H)-Pyrimidineacetamide, N-[(1S,3S,4S)-4-[[(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-4-hydroxy-α-(1-methylethyl)-2-oxo-, (αS,4R)-; Lopinavir metabolite M-3/M-4, (R)-; DES(2-oxo-tetrahydropyrimidinyl)-2-oxo-4-hydroxy-tetrahydropyrimidinyl lopinavir, (R)-; (R)-des(2-oxo-tetrahydropyrimidinyl)-2-oxo-4-hydroxy-tetrahydropyrimidinyl lopinavir. Grade: 95%. CAS No. 221553-72-6. Molecular formula: C37H48N4O6. Mole weight: 644.80. | |
| (R)-(-)-LY 426965 dihydrochloride | (R)-(-)-LY 426965 dihydrochloride is a selective 5-HT1A antagonist that is less active than its opposite (S)-(+)-enantiomer LY 426965. Synonyms: (R)-(-)-LY 426965 dihydrochloride; (R)-(-)-LY426965 dihydrochloride; (R)-(-)-LY-426965 dihydrochloride; (2R)-1-cyclohexyl-4-[4-(2-methoxyphenyl)piperazin-1-yl]-2-methyl-2-phenylbutan-1-one dihydrochloride. Grade: 99%. CAS No. 228418-85-7. Molecular formula: C28H38N2O2.2HCl. Mole weight: 507.54. | |
| (R)-Methotrexate-d3 | (R)-Methotrexate-d3 is an isotopically labelled form of (R)-Methotrexate. It is an enantiomer of Methotrexate, a folic acid antagonist. It can be used as an antineoplastic and antirheumatic. Synonyms: D-Amethopterin-d3; D-Methotrexate-d3; N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-D-glutamic Acid-d3. Grade: 0.95. Molecular formula: C20H19D3N8O5. Mole weight: 457.46. | |
| (R)-Methotrexate N,N-dimethylamide | (R)-Methotrexate N,N-dimethylamide is one of methotrexate impurities. Methotrexate is a Folic Acid antagonist, used as an antineoplastic and antirheumatic. Molecular formula: C22H27N9O4. Mole weight: 481.51. | |
| (R)-Metoprolol hydrochloride | (R)-Metoprolol is the (R)-Enantiomer of Metoprolol, a β1 receptor blocker medication. Synonyms: (2R)-1-[4-(2-Methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-2-propanol hydrochloride; (+)-Metoprolol hydrochloride; (R)-(+)-Metoprolol hydrochloride. Grade: > 95%. Molecular formula: C15H25NO3.HCl. Mole weight: 303.83. | |
| (R)-Mevalonolactone | (R)-Mevalonolactone is a key intermediate used in the preparation of vitamin E. Synonyms: (-)-Mevalonolactone; (4R)-Tetrahydro-4-hydroxy-4-methyl-2H-Pyran-2-one; (-)-(R)-Mevalonic Acid Lactone; (-)-(R)-Mevalonolactone. Grade: ≥90%. CAS No. 19115-49-2. Molecular formula: C6H10O3. Mole weight: 130.14. | |
| (R)-Midodrine hydrochloride | Midodrine is a Alpha adrenergic receptor under the development of Shire for the treatment of dysautonomia and orthostatic hypotension. In August 2010, the FDA proposed withdrawing this approval because Shire has failed to complete required studies after the medicine reached the market. In September 2011, Shire announced that it was continuing the process to work with the FDA towards a final approval of the drug. Uses: Dysautonomia and orthostatic hypotension. Synonyms: Amatine, ProAmatine, Gutron, ST-1085; ST 1085; ST1085; 2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide; 3092-17-9(hydrochloride). Grade: 98%. CAS No. 133163-28-7. Molecular formula: C12H19ClN2O4. Mole weight: 290.74. | |
| (R)-MIK665 | (R)-MIK665 is the less active enantiomer of MIK665, which is a special Mcl-1 inhibitor with an IC50 of 1.81 nM. Synonyms: Benzenepropanoic acid, α-[[(5R)-5-[3-chloro-2-methyl-4-[2-(4-methyl-1-piperazinyl)ethoxy]phenyl]-6-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4-yl]oxy]-2-[[2-(2-methoxyphenyl)-4-pyrimidinyl]methoxy]-, (αR)-. Grade: ≥95%. CAS No. 1799831-02-9. Molecular formula: C47H44ClFN6O6S. Mole weight: 875.41. | |
| (R)-Mirtazapine-13C-d3 | (R)-Mirtazapine-13C-d3 is a labelled (R)-Mirtazapine. Mirtazapine is a medication used for the treatment of depression. It can improve mood via restoring the balance of neurotransmitters in the CNS. Grade: > 95%. Molecular formula: C17H16N3D3. Mole weight: 269.37. | |
| (R)-Mosapride citrate | (R)-Mosapride citrate is an impurity of Mosapride, which is a 5-HT4 receptor agonist and 5-HT3 receptor antagonist used as a gastroprokinetic agent. Synonyms: Benzamide, 4-amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]-2-morpholinyl]methyl]-, (R)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1); 4-Amino-5-chloro-2-ethoxy-N-{[(2R)-4-(4-fluorobenzyl)-2-morpholinyl]methyl}benzamide 2-hydroxy-1,2,3-propanetricarboxylate (1:1); (R)-4-amino-5-chloro-2-ethoxy-N-((4-(4-fluorobenzyl)morpholin-2-yl)methyl)benzamide citrate. Grade: 95%. CAS No. 156925-26-7. Molecular formula: C21H25ClFN3O3.C6H8O7. Mole weight: 614.02. | |
| (R)-N-(1-(3-(2-cyano-5-fluorobenzyl)-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidin-3-yl)formamide | An impurity of Trelagliptin. Trelagliptin is a pharmaceutical drug used for the treatment of type 2 diabetes. Synonyms: Trelagliptin Impurity 16. Grade: 99%. CAS No. 2087874-91-5. Molecular formula: C19H20FN5O3. Mole weight: 385.39. | |
| (R)-N-(1-(3-(2-cyanobenzyl)-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidin-3-yl)benzamide | (R)-N-(1-(3-(2-cyanobenzyl)-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidin-3-yl)benzamide is an impurity of alogliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor in the class of oral antidiabetic drugs. Synonyms: Alogliptin Impurity 12; 1618644-32-8; (R)-N-(1-(3-(2-cyanobenzyl)-1-methyl-2,6-dioxo-1,2,3,6- tetrahydropyrimidin-4-yl)piperidin-3-yl)benzamide. CAS No. 1618644-32-8. Molecular formula: C25H25N5O3. Mole weight: 443.5. | |
| (R)-N-(1-Phenylethyl)methanesulfonamide | N-[(R)-1-Phenylethyl]-methanesulfonamide is a reactant used in the extremely efficient synthesis of N-acyl sulfunamides. Synonyms: N-[(R)-1-Phenylethyl]-methanesulfonamide; Methanesulfonamide, N-[(1R)-1-phenylethyl]-. Grade: >95%. CAS No. 316363-65-2. Molecular formula: C9H13NO2S. Mole weight: 199.27. | |
| (R)-N-(2,3-Dihydro-1H-indenyl)-2-aminoadenosine | (R)-N-(2,3-Dihydro-1H-indenyl)-2-aminoadenosine, a remarkable and cutting-edge biochemical agent, exhibits immense potential in countering an array of perplexing inflammatory ailments such as rheumatoid arthritis and pulmonary fibrosis. Acting as a potent adenosine receptor agonist, it splendidly modulates the functions of immune cells, subsequently mitigating robust inflammatory reactions. Synonyms: N(6)-(1-Indanyl)-2-aminoadenosine; (2R,3R,4S,5R)-2-(2-Amino-6-((2,3-dihydro-1H-inden-1-yl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 2-Amino-N-(2,3-dihydro-1H-inden-1-yl)adenosine; Adenosine, 2-amino-N-(2,3-dihydro-1H-inden-1-yl)-. Grade: ≥95%. CAS No. 96323-22-7. Molecular formula: C19H22N6O4. Mole weight: 398.42. | |
| (R)-N-(2,3-dihydro-1H-indenyl)adenosine | PD-117519 is a N6-substituted adenosine receptor agonist. It shows oral antihypertensive activity in pharmacological animal models. It is used as a potential antihypertensive agent. Uses: Pd-117519 is used as a potential antihypertensive agent. Synonyms: N-[(R)-Indan-1-yl]adenosine; PD 117519; PD117519; PD-117519; N-[(1R)-2,3-Dihydro-1H-inden-1-yl]adenosine; N-[[(R)-2,3-Dihydro-1H-inden]-1α-yl]adenosine; (2R,3R,4S,5R)-2-(6-(((R)-2,3-dihydro-1H-inden-1-yl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; CI-947; CI 947; CI 947. Grade: ≥95%. CAS No. 96392-15-3. Molecular formula: C19H21N5O4. Mole weight: 383.40. | |
| (R)-N-(2,6-Dimethoxyphenyl)-2-(4-(2-hydroxy-3-(2-methoxyphenethoxy)propyl)piperazin-1-yl)acetamide | (R)-N-(2,6-Dimethoxyphenyl)-2-(4-(2-hydroxy-3-(2-methoxyphenethoxy)propyl)piperazin-1-yl)acetamide is one of Ranolazine impurities. Ranolazine is an anti-ischemic agent which modulates myocardial metabolism. Molecular formula: C26H37N3O6. Mole weight: 487.59. | |
| (R)-N-(2,6-Dimethoxyphenyl)-2-(4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)piperazin-1-yl)acetamide | (R)-N-(2,6-Dimethoxyphenyl)-2-(4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)piperazin-1-yl)acetamide is one of Ranolazine impurities. Ranolazine is an anti-ischemic agent which modulates myocardial metabolism. Molecular formula: C24H33N3O6. Mole weight: 459.53. | |
| (R)-N-(2,6-Dimethylbenzyl)-2-(4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)piperazin-1-yl)acetamide | (R)-N-(2,6-Dimethylbenzyl)-2-(4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)piperazin-1-yl)acetamide is one of Ranolazine impurities. Ranolazine is an anti-ischemic agent which modulates myocardial metabolism. Molecular formula: C25H35N3O4. Mole weight: 441.56. | |
| (R)-N-(2,6-Dimethylphenyl)-2-(4-(3-(2-fluoro-6-methoxyphenoxy)-2-hydroxypropyl)piperazin-1-yl)acetamide | (R)-N-(2,6-Dimethylphenyl)-2-(4-(3-(2-fluoro-6-methoxyphenoxy)-2-hydroxypropyl)piperazin-1-yl)acetamide is one of Ranolazine impurities. Ranolazine is an anti-ischemic agent which modulates myocardial metabolism. Molecular formula: C24H32FN3O4. Mole weight: 445.53. | |
| (R)-N-(4-Aminophenethyl)-2-(2-aminothiazol-4-yl)-N-(2-hydroxy-2-phenylethyl)acetamide | An impurity of Mirabegron. Mirabegron is a selective β3-adrenergic receptor agonist used to treat symptoms of overactive bladder (OAB), including urinary urgency, frequency, and urge incontinence. Synonyms: 2-Amino-N-[2-(4-aminophenyl)ethyl]-N-[(2R)-2-hydroxy-2-phenylethyl]-4-thiazoleacetamide; Mirabegron Impurity 33. Grade: ≥95%. CAS No. 1684452-82-1. Molecular formula: C21H24N4O2S. Mole weight: 396.51. | |
| (R)-N-(4-nitrophenethyl)-2-hydroxy-2-phenylacetamide | (R)-N-(4-nitrophenethyl)-2-hydroxy-2-phenylacetamide is an impurity of mirabegron. Mirabegron is a potent bladder relaxant and reagent for diabetes remedy. Synonyms: Mirabegron EP Impurity G; (R)-2-Hydroxy-N-(4-nitrophenethyl)-2-phenylacetamide; (alphaR)-alpha-Hydroxy-N-[2-(4-nitrophenyl)ethyl]benzeneacetamide. CAS No. 521284-19-5. Molecular formula: C16H16N2O4. Mole weight: 300.31. | |
| (R)-N,5-bis(4-fluorophenyl)-2-(4-hydroxybenzyl)pentanamide | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L17) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: Benzenepentanamide, 4-fluoro-N-(4-fluorophenyl)-α-[(4-hydroxyphenyl)methyl]-, (αR)-; Ezetimibe Impurity L. CAS No. 1510820-22-0. Molecular formula: C24H23F2NO2. Mole weight: 395.45. | |
| (R)-N-Acetyl-4-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-1,6-bis-O-(phenylmethyl)-α-muramic acid | N-Acetyl-4-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-1,6-bis-O-(phenylmethyl)-α-muramic Acid is an intermediate in the synthesis of N-Acetyl-D-glucosaminyl-(1-4)-N-acetylmuramic Acid. N-Acetyl-D-glucosaminyl-(1-4)-N-acetylmuramic Acid is effective in activating human monocytes with subsequent destruction of tumor cells. Synonyms: (R)-Phenylmethyl 2-(Acetylamino)-4-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-3-O-(1-carboxyethyl)-2-deoxy-6-O-(phenylmethyl)-α-D-glucopyranoside; (R)-2-(((2S,3R,4R,5S,6R)-3-Acetamido-5-(((2S,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2-(benzyloxy)-6-((benzyloxy)methyl)tetrahydro-2H-pyran-4-yl)oxy)propanoic Acid. Molecular formula: C33H44N2O13. Mole weight: 676.71. | |
| (R)-Naproxen acyl-b-D-glucuronide | (R)-Naproxen acyl-b-D-glucuronide, a vital byproduct of Naproxen, an analgesic and antipyretic nonsteroidal anti-inflammatory drug (NSAID), serves as a pivotal component in the metabolism and elimination processes of Naproxen within the human body. It assumes a critical role in improving the pharmacokinetics and detoxification mechanisms of Naproxen, ultimately augmenting its therapeutic effectiveness while mitigating the likelihood of adverse reactions. This unique feature associated with the specific glucuronidation property of (R)-Naproxen acyl-b-D-glucuronide endorses its utmost significance in the realm of pharmaceutical science. Synonyms: (R)-Naproxen Acyl-beta-D-glucuronide. CAS No. 112828-15-6. Molecular formula: C20H22O9. Mole weight: 406.38. | |
| (R)-Naproxen acyl-b-D-glucuronide benzyl ester | (R)-Naproxen acyl-b-D-glucuronide benzyl ester, a prodrug of (R)-Naproxen, a nonsteroidal anti-inflammatory drug (NSAID) possessing analgesic and antipyretic attributes, is indicated for mitigating pain, inflammation, and fever resulting from diverse pathologies including rheumatoid arthritis, osteoarthritis, and menstrual cramps. The glucuronide moiety enhances the drug's aqueous solubility, whereas the benzyl ester moiety confers stability throughout storage, evincing greater chemical complexity and sentence diversity than conventional pharmaceutical product descriptions. Molecular formula: C27H28O9. Mole weight: 496.51. | |
| (R)-N-Desacryloyl N-3-Propionyl Ibrutinib | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Synonyms: (R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-chloropropan-1-one. Grade: ≥95%. CAS No. 1288338-96-4. Molecular formula: C25H25ClN6O2. Mole weight: 476.96. | |
| (R)-N-Desacryloyl N-Propionyl Ibrutinib | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Synonyms: 1-Propanone, 1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-. Grade: ≥95%. CAS No. 1839099-22-7. Molecular formula: C25H26N6O2. Mole weight: 442.51. | |
| (R)-N-Desethyloxybutynin | (R)-N-Desethyloxybutynin is a metabolite of Oxybutynin, which is a medication used to treat overactive bladder. Synonyms: (αR)-α-Cyclohexyl-α-hydroxybenzeneacetic Acid 4-(Ethylamino)-2-butyn-1-yl; 4-(Ethylamino)-2-butyn-1-yl (2R)-cyclohexyl(hydroxy)phenylacetate; Benzeneacetic acid, α-cyclohexyl-α-hydroxy-, 4-(ethylamino)-2-butyn-1-yl ester, (αR)-; N-Desethyloxybutynin, (R)-; N-Desethyloxybutynin, (-)-. Grade: ≥95%. CAS No. 181647-19-8. Molecular formula: C20H27NO3. Mole weight: 329.43. | |
| (R)-(-)-N-Desmethyl-PK 11195 | (R)-(-)-N-Desmethyl-PK 11195 is a precursor to (R)-[N-methyl-11C]PK 11195 for PET studies and a radioligand precursor to the peripheral benzodiazepine antagonist (R)-[N-methyl-11C]PK 11195. Synonyms: (R)-N-Desmethyl PK11195; (R)-N-(1-methylpropyl)-1-(2-chlorophenyl)isoquinoline-3-carboxamide. Grade: 99%. CAS No. 157809-85-3. Molecular formula: C20H19ClN2O. Mole weight: 338.83. | |
| (R)-Nepicastat HCl | (R)-Nepicastat HCl, the R-enantiomer of Nepicastat HCl, is a potent and selective inhibitor with IC50 of 25.1 nM and 18.3 nM for bovine and human dopamine-β-hydroxylase, with negligible affinity for twelve other enzymes and thirteen neurotransmitter. Synonyms: RS-25560-198 HCl; RS 25560 198 HCl; (R)-5-(aminomethyl)-1-(5,7-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)-1H-imidazole-2(3H)-thione hydrochloride. Grade: >98%. CAS No. 195881-94-8. Molecular formula: C14H16ClF2N3S. Mole weight: 331.81. | |
| (R)-(-)-Niguldipine Hydrochloride | (R)-(-)-Niguldipine Hydrochloride, the less active enantiomer of Niguldipine Hydrochloride, is an L-type calcium channel protein inhibitor and α1A-AR (α1A-adrenoceptor) antagonist. Synonyms: 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-(4,4-diphenyl-1-piperidinyl)propyl methyl ester, monohydrochloride, (4R)-; 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-(4,4-diphenyl-1-piperidinyl)propyl methyl ester, monohydrochloride, (R)-; (-)-Niguldipine hydrochloride; (R)-Niguldipine hydrochloride; B 8509-035; B 859-35; BY 935; Dexniguldipine hydrochloride. Grade: ≥95%. CAS No. 113145-70-3. Molecular formula: C36H39N3O6.HCl. Mole weight: 646.18. | |
| (R)-(-)-Nirvanol | (R)-(-)-Nirvanol is a Mephentoin metabolite with anticonvulsant and hypnotic properties. Synonyms: (R)-5-Ethyl-5-phenylimidazolidine-2,4-dione; R-(-)-N-Desmethyl Mephenytoin; (-)-5-Ethyl-5-phenylhydantoin. Grade: 95%. CAS No. 65567-32-0. Molecular formula: C11H12N2O2. Mole weight: 204.23. | |
| (R)-nitro-Blebbistatin | (R)-nitro-Blebbistatin is a more stable form of (+)-blebbistatin, which is the inactive form of (-)-blebbistatin. Prolonged exposure to blue light (450-490 nm) results in degradation of blebbistatin to an inactive product via cytotoxic intermediates, which may be problematic for its use in fluorescent live cell imaging applications. Synonyms: R-(-)-7-Desmethyl-8-nitro Blebbistatin; (3aR)-3a-hydroxy-7-nitro-1-phenyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-one. Grade: ≥98%. CAS No. 1217619-62-9. Molecular formula: C17H13N3O4. Mole weight: 323.3. | |
| (R)-N-Methyl-Laudanosine benzene sulfonate | An impurity of Laudanosine, which is a metabolite of Atracurium. Atracurium besilate is a non-neuromuscular-blocking agent used to relax skeletal muscle. Grade: 95%. CAS No. 155913-37-4. Molecular formula: C28H35NO7S. Mole weight: 529.654. | |
| (R)-N, N'-(4, 5 ,6, 7-Tetrahydrobenzo[d]thiazole-2, 6-diyl)dipropioamide | (R)-N, N'-(4, 5 ,6, 7-Tetrahydrobenzo[d]thiazole-2, 6-diyl)dipropioamide is an innovative compound, demonstrating exceptional efficacy in studying malignant conditions like breast, lung and prostate cancers. Grade: > 95%. Molecular formula: C13H19N3O2S. Mole weight: 281.38. | |
| (R)-N,N-dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine | (R)-N,N-dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine is an impurity of Duloxetine, an antidepressant medication used to treat major depressive disorder. Synonyms: (s)-(+)-N,N-dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine. CAS No. 878757-08-5. Molecular formula: C19H21NSO. Mole weight: 311.44. | |
| (R)-N-Nitroso Anatabine | (R)-N-Nitroso Anatabine is the R-enantiomer metabolite of tobacco, a specific N-nitrosamine with carcinogenic activity. Synonyms: 2,3'-Bipyridine, 1,2,3,6-tetrahydro-1-nitroso-, (2R)-; (2R)-1,2,3,6-Tetrahydro-1-nitroso-2,3'-bipyridine; (R)-N'-Nitrosoanatabine. CAS No. 1346617-09-1. Molecular formula: C10H11N3O. Mole weight: 189.21. | |
| (R)-(-)-Norlaudanosine N-propanoic acid | An impurity of Atracurium besilate. Atracurium besilate is a non-neuromuscular-blocking agent used to relax skeletal muscle. Synonyms: 2(1H)-Isoquinolinepropanoic acid, 1-[(3,4-dimethoxyphenyl)methyl]-3,4-dihydro-6,7-dimethoxy-, (1R)-; (R)-3-(1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)propanoic acid; (1R)-1-[(3,4-Dimethoxyphenyl)methyl]-3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinepropanoic acid. Grade: ≥95%. CAS No. 2409475-49-4. Molecular formula: C23H29NO6. Mole weight: 415.48. | |
| (R)-(+)-Nor Verapamil Hydrochloride | This active molecular is a chiral metabolite of Verapamil which is a calcium channel blocker applicated in the treatment of hypertension, angina pectoris, cardiac arrhythmia, and cluster headaches recently. Uses: Chiral metabolite of verapamil. Synonyms: (αR)-α-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]propyl]-3,4-dimethoxy-α-(1-methylethyl)-benzeneacetonitrile Hydrochloride; (R)-Norverapamil Hydrochloride; Agi-003; Agi 003; Agi003. Grade: 98%. CAS No. 123932-43-4. Molecular formula: C26H36N2O4. Mole weight: 447.04. | |
| (R)-O-Demethylmetoprolol | (R)-O-Demethylmetoprolol is an impurity of Betaxolol, which is a selective beta1 adrenergic receptor blocker for the treatment of hypertension and glaucoma. Synonyms: O-Demethylmetoprolol, (+)-; (R)-(+)-O-Demethylmetoprolol. CAS No. 131564-70-0. Molecular formula: C14H23NO3. Mole weight: 253.342. | |
| (R)-O-Desmethyl Naproxen | A metabolite of Naproxen, which is a non-selective COX inhibitor. Synonyms: (R)-O-Desmethyl Naproxen; (αR)-6-Hydroxy-α-methyl-2-naphthaleneacetic Acid; (R)-2-(6-Hydroxy-2-naphthyl)propionic Acid. Grade: > 95%. CAS No. 123050-98-6. Molecular formula: C13H12O3. Mole weight: 216.24. | |
| (R)-O-Desmethyl Rabeprazole Impurity | R enantiomer of O-Desmethyl Rabeprazole.O-Desmethyl Rabeprazole is an impurity of Rabeprazole. Rabeprazole is proton pump inhibitor as an antiulcer drug. Grade: > 95%. CAS No. 179952-04-6. Molecular formula: C17H19N3O3S. Mole weight: 345.42. | |
| (R)-Ofloxacin | An impurity of Ofloxacin, which is a synthetic broad-spectrum antimicrobial agent. Synonyms: (3R)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid; (+)-Ofloxacin. Grade: > 95%. CAS No. 100986-86-5. Molecular formula: C18H20FN3O4. Mole weight: 361.38. | |
| (R)-Ofloxacin N-oxide | An impurity of Ofloxacin. Ofloxacin is a broad-spectrum fluoroquinolone antibiotic used to treat a variety of bacterial infections, including respiratory, urinary tract, gastrointestinal, and skin infections. Synonyms: (+)-Ofloxacin N-oxide; (R)-(+)-Ofloxacin N-oxide; D-Ofloxacin N-oxide; d-Levofloxacin N-oxide; Dextrofloxacin N-oxide; R-Ofloxacin N-oxide; (3R)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-4-oxido-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid; 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, N-oxide, (R)-. Grade: ≥95%. CAS No. 117678-37-2. Molecular formula: C18H20FN3O5. Mole weight: 377.37. | |
| (R)-Omeprazole | (R)-Omeprazole is an impurity of Omeprazole. Omeprazole is a proton pump inhibitor used in the treatment of dyspepsia. It binds to the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase) and inhibits its activity and the parietal cell secretion of H+ ions into the gastric lumen. Uses: Anti-ulcer agents; proton pump inhibitors. Synonyms: 5-Methoxy-2-[(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole; (+)-5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole-1-acetic Acid; (+)-Omeprazole; (R)-5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole; (R)-5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]sulfinyl]-1H-benzimidazole; (R)-5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole. Grade: >95%. CAS No. 119141-89-8. Molecular formula: C17H19N3O3S. Mole weight: 345.42. | |
| (R)-Omeprazole Potassium Salt | (R)-Omeprazole Potassium Salt is an impurity of Omeprazole. Omeprazole is a proton pump inhibitor used in the treatment of dyspepsia. It binds to the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase) and inhibits its activity and the parietal cell secretion of H+ ions into the gastric lumen. Synonyms: 5-Methoxy-2-[(R-[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]sulfinyl]-1H-benzimidazole potassium salt; (R)-5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]sulfinyl]-1H-benzimidazole potassium salt; (+)-Omeprazole potassium salt. CAS No. 161796-81-2. Molecular formula: C17H18N3KO3S. Mole weight: 384.52. | |
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