BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
An impurity of Levofloxacin, which is as efficacious as or more efficacious than that with ciprofloxacin in systemic as well as pyelonephritis infections in mice. Synonyms: (2S)-6,7-difluoro-2-methyl-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid. Grade: > 95 %. CAS No. 100986-89-8. Molecular formula: C13H9F2NO4. Mole weight: 281.21.
(S)-9-(2,3-Dihydroxypropyl)-2-amino-6-chloropurine, a chemical compound commonly used in the biomedical industry, demonstrates the potential to impede viral DNA synthesis, rendering it a likely antiviral agent. Synonyms: (S)-3-(2-Amino-6-chloro-purin-9-yl)-propane-1,2-diol. Grade: ≥95%. CAS No. 885322-01-1. Molecular formula: C8H10ClN5O2. Mole weight: 243.65.
(S)-9-(2,3-Dihydroxypropyl)-guanine
(S)-9-(2,3-Dihydroxypropyl)-guanine, a pharmaceutical intermediate essential in the synthesis of Acyclovir, an antiviral drug used to combat a variety of viruses. This remarkable molecule showcases its ability to inhibit viral DNA replication, thereby shortening the duration of infections. It is one of the most potent antiviral agents currently available in the market and has been extensively researched and studied to successfully treat and alleviate viral infections. Synonyms: 9-(S)-(2,3-dihydroxypropyl)guanine; 6H-Purin-6-one, 2-amino-9-[(2S)-2,3-dihydroxypropyl]-1,9-dihydro-; (S)-2-amino-9-(2,3-dihydroxypropyl)-1,9-dihydro-6H-purin-6-one; 1-Deoxy-1-(2-amino-6-oxo-1,6-dihydro-9H-purine-9-yl)-D-glycerol. Grade: ≥95%. CAS No. 117143-84-7. Molecular formula: C8H11N5O3. Mole weight: 225.20.
(S)-9-[3-(4,4'-Dimethoxytrityloxy)-2-hydroxypropyl]-N2-isobutyrylguanine, a chemical employed in the realm of biomedicine, is of prime utility for combating viral infections by thwarting viral replication. Herpes simplex and varicella-zoster, among other viruses, fall under its ambit. As a reference standard, it is widely deployed to scrutinize the antiviral potential of nucleoside analogs. Synonyms: Propanamide, N-[9-[(2S)-3-[bis(4-methoxyphenyl)phenylmethoxy]-2-hydroxypropyl]-6,9-dihydro-6-oxo-1H-purin-2-yl]-2-methyl-; N-(9-{(S)-3-[Bis-(4-methoxy-phenyl)-phenyl-methoxy]-2-hydroxy-propyl}-6-oxo-6,9-dihydro-1H-purin-2-yl)-isobutyramide. Grade: ≥95%. CAS No. 182625-67-8. Molecular formula: C33H35N5O6. Mole weight: 597.66.
(S)-9-Hydroxy Risperidone ((S)-Paliperidone)
An impurirty of Risperidone,Risperidone is a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist. Synonyms: (9S)-3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro -9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one; (-)-9-Hydroxyrisperidone; 9-(S)-Paliperidone. Grade: > 95%. CAS No. 147663-01-2. Molecular formula: C23H27FN4O3. Mole weight: 426.5.
(S)-Acenocoumarol
Acenocoumarol is a short-lived oral anticoagulant, which, like warfarin, functions by inhibiting vitamin K epoxide reductase. It has higher intrinsic anticoagulant potency than warfarin and phenprocoumon, when evaluated in vitro. Synonyms: (S)-Acenocoumarin; (S)-Nicoumalone; (S)-(-)-Nicoumalone; 4-hydroxy-3-[(1S)-1-(4-nitrophenyl)-3-oxobutyl]chromen-2-one. Grade: ≥98%. CAS No. 66556-78-3. Molecular formula: C19H15NO6. Mole weight: 353.3.
(S)-(+)-AE 0047
(S)-(+)-AE 0047 is an isomer of Vatanidipine, which is a dihydropyridine (DHP)-type calcium channel blocker used as an antihypertensive agent. Synonyms: 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-[2-[4-[4-(diphenylmethyl)-1-piperazinyl]phenyl]ethyl] 5-methyl ester, hydrochloride (1:2), (4S)-; 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-[4-[4-(diphenylmethyl)-1-piperazinyl]phenyl]ethyl methyl ester, dihydrochloride, (S)-; (+)-AE 0047; (S)-AE 0047; 3-(4-(4-benzhydrylpiperazin-1-yl)phenethyl) 5-methyl (S)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate dihydrochloride; Watanidipine dihydrochloride. Grade: ≥95%. CAS No. 189624-85-9. Molecular formula: C41H42N4O6.2HCl. Mole weight: 759.72.
(S)-Alogliptin Benzoate Salt
(S)-Alogliptin Benzoate Salt is an impurity of alogliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor in the class of oral antidiabetic drugs. Synonyms: 2-[[6-[(3S)-3-Amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile Benzoate; (S)-2-((6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile benzoate. CAS No. 1638544-64-5. Molecular formula: C25H27N5O4. Mole weight: 461.51.
(S)-α-[3-[2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-4-methoxy-2-carboxylatebenzenepropanol Methyl Ester is an intermediate in the production of Montelukast, which is a leukotriene receptor antagonist indicated for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Synonyms: methyl (S,E)-2-(3-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-hydroxypropyl)-5-methoxybenzoate; Methyl 2-[(3S)-3-{3-[(E)-2-(7-chloro-2-quinolinyl)vinyl]phenyl}-3-hydroxypropyl]-5-methoxybenzoate; Benzoic acid, 2-[(3S)-3-[3-[(E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxypropyl]-5-methoxy-, methyl ester. Molecular formula: C29H26ClNO4. Mole weight: 487.97.
It is an impurity arising in the synthesis of Darifenacin. Synonyms: 3-(S)-(+)-(1-Carbamoyl-1,1-diphenylmethyl)pyrroloidine-L-(+)-tartarate; (3S)-α,α-Diphenyl-3-pyrrolidineacetamide (2R,3R)-2,3-Dihydroxybutanedioate; (S)-3-(1-Carbamoyl-1,1-diphenylmethyl)pyrrolidine L-Tartrate; 3-(S)-(1-Carbamoyl-1,1-diphenylmethyl)pyrrolidine Tartrate. Grade: ≥95%. CAS No. 134002-26-9. Molecular formula: C22H26N2O7. Mole weight: 430.45.
(S)-α,α-Diphenylprolinol Hydrochloride
(S)-α,α-Diphenylprolinol Hydrochloride is the (S)-enantiomer of Diphenylprolinol, which is a norepinephrine-dopamine reuptake inhibitor used as a designer drug. Synonyms: (S)-α,α-Diphenyl-2-pyrrolidinemethanol Hydrochloride; (S)-D2PM Hydrochloride; (2S)-α,α-Diphenyl-2-pyrrolidinemethanol Hydrochloride; α,α-Diphenyl-L-prolinol Hydrochloride. Grade: ≥95%. CAS No. 148719-90-8. Molecular formula: C17H20ClNO. Mole weight: 289.80.
(S)-alpha-cyclopropyl-5-ethyl-2-thiophenemethanamine is a compound of immense value, finding extensive application within the biomedical field, most notably those pertaining to the central nervous system. It serves as a potent agonist or antagonist to precise receptors. Grade: > 95%. CAS No. 1212863-08-5. Molecular formula: C10H15NS. Mole weight: 181.30.
(S)-(+)-α-Fluoromethylhistidine Dihydrochloride
(S)-(+)-α-Fluoromethylhistidine Dihydrochloride is a histidine carboxylase inhibitor. Synonyms: α-Fluoromethylhistidine Dihydrochloride; α-(Fluoromethyl)-L-histidine Dihydrochloride. Molecular formula: C7H12Cl2FN3O2. Mole weight: 260.09.
(S)-alpha-methyl-6-(dimethylamino)-3-pyridinemethanamine is a paramount compound, functioning as a potent agonist. This compound selectively interacts with designated receptors within the central nervous system, facilitating enhanced disease research strategies. Its exceptional effectiveness renders it indispensable in studying neurodegenerative conditions, including Alzheimer's disease and Parkinson's. Synonyms: 5-[(1S)-1-aminoethyl]-N,N-dimethylpyridin-2-amine; AKOS017515805; 1259881-59-8; EN300-1837321. Grade: > 95%. CAS No. 1259881-59-8. Molecular formula: C9H15N3. Mole weight: 165.24.
(S)-(+)-α-Methylhistamine dihydrobromide
(S)-(+)-α-Methylhistamine dihydrobromide is the less active enantiomer of histamine H3 receptor agonist R-(-)-α-methylhistamine, with 120-fold less potent than R-(-) at H3. Synonyms: (S)-(+)-α-Methyl-1H-imidazole-4-ethanamine dihydrobromide; (S)-a-Methyl-1H-imidazole-4-ethanamine; (aS)-a-Methyl-1H-imidazole-4-ethanamine (9CI); (aS)-a-Methyl-1H-imidazole-5-ethanamine; (S)-a-Methylhistamine; S-(+)-a-Methylhistamine. CAS No. 75614-93-6. Molecular formula: C6H11N3.2HBr. Mole weight: 287.
(S)-Amino-(2-chloro-phenyl)-acetic acid hydrochloride is an impurity of Clopidogrel, an antithrombotic agent. Synonyms: (S)-2-Amino-2-(2-chlorophenyl)acetic acid hydrochloride. Grade: 95%. CAS No. 225918-58-1. Molecular formula: C8H9Cl2NO2. Mole weight: 222.07.
(S)-Amlodipine Di-p-Toluoyl-D-tartrate
(S)-Amlodipine Di-p-Toluoyl-D-tartrate is an impurity of Amlodipine. Amlodipine is a long-acting dihydropyridine L-type calcium channel blocker. Amlodipine is used to lower blood pressure and prevent chest pain. Synonyms: (4S)-2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic Acid 3-Ethyl 5-Methyl Ester Di-p-Tolyoyl-D-tartrate; (-)-Amlodipine Di-p-Tolyoyl-D-tartrate; (S)-(+)-Amlodipine Di-p-Tolyoyl-D-tartrate. CAS No. 1215226-53-1. Molecular formula: C40H43ClN2O13. Mole weight: 795.23.
(S)-AMPA
(S)-AMPA is an active enantiomer of AMPA, which has been found to be a definitive agonist of the AMPA glutamatergic ionotropic receptor. Synonyms: (S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid. Grade: ≥99% by HPLC. CAS No. 83643-88-3. Molecular formula: C7H10N2O4. Mole weight: 186.17.
[Sar9,Met(O2)11]-Substance P acetate
A selective agonist of tachykinin NK1 receptor. Synonyms: 9-Sar-11-met(O2)-substance P acetate; 9-Sarcosyl-11-methionine(O2)-substance P acetate. Molecular formula: C67H106N18O17S. Mole weight: 1467.75.
[Sar9,Met(O2)11]-Substance P TFA
A selective agonist of tachykinin NK1 receptor. Grade: 99%. Molecular formula: C66H101N18F3O17S. Mole weight: 1507.68.
(S)-Aspartimide
(S)-Aspartimide is a bioactive byproduct formed during solid-phase peptide synthesis (SPPS) of aspartic acid-containing peptides. Aspartimide is formed by cyclization of aspartic acid during Fmoc removal or peptide coupling. Synonyms: L-3-aminosuccinimide; (S)-2-Aminosuccinimide. Grade: >95%. CAS No. 73537-92-5. Molecular formula: C4H6N2O2. Mole weight: 114.10.
(S)-(-)-Atenolol
(S)-(-)-Atenolol is the active enantiomer of (RS)-atenolol, which is a cardioselective β-adrenergic blocker. It has antihypertensive, antianginal, antiarrhythmic (class II) effects. Synonyms: (S)-Atenolol; 4-[(2S)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide; (-)-Atenolol; Esatenolol; (S)-(-)-4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide; (-)-4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide. Grade: ≥97% by HPLC. CAS No. 93379-54-5. Molecular formula: C14H22N2O3. Mole weight: 266.34.
(S)-ATP-beta-S
(S)-ATP-beta-S is a P2Y receptor agonist. In the scientific investigation encompassing purinergic neurotransmission, inflammatory processes, and blood platelet aggregation, its role is paramount. Synonyms: (S)-ATPβS. CAS No. 59261-36-8. Molecular formula: C10H16N5O12P3S. Mole weight: 523.25.
(S)-Azelastine HCl
(S)-Azelastine HCl is the S configuration of Azelastine HCl. Synonyms: (S)-Azelastine Hydrochloride; (S)-4-[(4-Chlorophenyl)methyl]-2-(hexahydro-1-methyl-1H-azepin-4-yl)-1(2H)-phthalazinone Hydrochloride; (+)-Azelastine Hydrochloride; 1(2H)-Phthalazinone, 4-[(4-chlorophenyl)methyl]-2-(hexahydro-1-methyl-1H-azepin-4-yl)-, monohy. Grade: > 95%. CAS No. 153408-27-6. Molecular formula: C22H25Cl2N3O. Mole weight: 418.36.
(S)-Azelastine N-Oxide
(S)-Azelastine N-Oxide is a metabolite of (S)-Azelastine. Synonyms: (S)-Azelastine N-Oxide (Mixture of Diastereomers); (S)-4-[(4-Chlorophenyl)methyl]-2-(hexahydro-1-methyl-1-oxido-1H-azepin-4-yl)-1(2H)-phthalazinone; (+)-Azelastine N-Oxide. Grade: > 95%. CAS No. 1346617-06-8. Molecular formula: C22H24ClN3O2. Mole weight: 397.91.
(S)-Baclofen
(S)-Baclofen is the S-enantiomer of Baclofen, which is a specific GABA-B receptor agonist and muscle relaxant (skeletal). It is primarily used to treat spasticity. Uses: S-enantiomer of baclofen. specific gaba-b receptor agonist. muscle relaxant (skeletal). Synonyms: (βS)-β-(Aminomethyl)-4-chlorobenzenepropanoic Acid; (+)-Baclofen; (S)-4-Amino-3-(4-chlorophenyl)butanoic Acid; (S)-4-Amino-3-(4-chlorophenyl)butyric Acid; (S)-Baclofen; L-(+)-Baclofen; L-Baclofen; S(+)-Baclofen; d-Baclofen. Grade: 98%. CAS No. 66514-99-6. Molecular formula: C10H12ClNO2. Mole weight: 213.66.
(S)-Bendroflumethiazide
(S)-Bendroflumethiazide is the S-enatiomer of the diuretic Bendroflumethiazide. Synonyms: (3S)-3,4-Dihydro-3-(phenylmethyl)-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-Dioxide. Grade: > 95%. CAS No. 1245935-40-3. Molecular formula: C15H14F3N3O4S2. Mole weight: 421.42.
(S)-beta-amino-5-methoxy-2-pyridineethanol
(S)-beta-amino-5-methoxy-2-pyridineethanol is a compound used in studying neurological disorders like Alzheimer's disease. This product has shown promise in inhibiting the activity of certain enzymes that contribute to the formation of amyloid plaques is a hallmark of Alzheimer's pathology. Synonyms: EN300-1868258; (2S)-2-amino-2-(5-methoxypyridin-2-yl)ethan-1-ol. Grade: > 95%. CAS No. 1213927-86-6. Molecular formula: C8H12N2O2. Mole weight: 168.20.
(S)-BI 665915
(S)-BI 665915 is an orally active inhibitor of 5-lipoxygenase-activating protein (FLAP) containing oxadiazole, with an IC50 of 1.7 nM for binding to FLAP. It inhibits the function of FLAP in human whole blood with an IC50 of 45 nM. It has excellent cross-species drug metabolism and pharmacokinetic (DMPK) properties, and has a dose-dependent inhibition of LTB4 production. Synonyms: 2-[4-(3-{(1S)-1-[4-(2-Amino-5-pyrimidinyl)phenyl]-1-cyclopropylethyl}-1,2,4-oxadiazol-5-yl)-1H-pyrazol-1-yl]-N,N-dimethylacetamide; 1H-Pyrazole-1-acetamide, 4-[3-[(1S)-1-[4-(2-amino-5-pyrimidinyl)phenyl]-1-cyclopropylethyl]-1,2,4-oxadiazol-5-yl]-N,N-dimethyl-. Grade: ≥95%. CAS No. 1360550-05-5. Molecular formula: C24H26N8O2. Mole weight: 458.52.
(S)-Bromoenol lactone
(S)-Bromoenol lactone is an irreversible inhibitor of iPLA2γ. Synonyms: (S)-BEL; 6E-(bromoethylene)tetrahydro-3S-(1-naphthalenyl)-2H-pyran-2-one. Grade: ≥98%. CAS No. 478288-94-7. Molecular formula: C16H13BrO2. Mole weight: 317.2.
(S)-Bromoenol lactone-d7
(S)-Bromoenol lactone-d7 ((S)-BEL-d7) contains seven deuterium atoms at the 2, 3, 4, 5, 6, 7, and 8 positions. It is intended for use as an internal standard for the quantification of (S)-BEL by GC- or LC-mass spectrometry (MS). Synonyms: (S)-BEL-d7; 6E-(bromoethylene)tetrahydro-3S-(1-naphthalenyl)-2H-pyran-2-one. Grade: ≥99% atom D. Molecular formula: C16H6BrD7O2. Mole weight: 324.2.
(S)-Bufuralol HCl
(S)-Bufuralol HCl is the S-Enantiomer of Bufuralol Hydrochloride. Synonyms: (S)-Bufuralol Hydrochloride; (αS)-α-[[(1,1-Dimethylethyl)amino]methyl]-7-ethyl-2-benzofuranmethanol; (-)-Bufuralol Hydrochloride; l-Bufuralol Hydrochloride. Grade: > 95%. CAS No. 57704-10-6. Molecular formula: C16H24NO2Cl. Mole weight: 297.83.
(S)-C33
(S)-C33 is a potent and selective PDE9 inhibitor (IC50 = 11 nM). Synonyms: PDE9-IN-(S)-C33; PDE9IN(S)C33; PDE9 IN (S) C33; (S)-C33; 49D; 6-[[(1S)-1-(4-Chlorophenyl)ethyl]amino]-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one. Grade: ≥98% by HPLC. CAS No. 2066488-39-7. Molecular formula: C18H20ClN5O. Mole weight: 357.84.
(S)-Carisbamate
(S)-Carisbamate was studied as adjunctive treatment of partial onset seizures in adults, and also exhibited neuroprotective and antiepileptogenic properties in rodent epilepsy models. Uses: Carisbamate is being developed for adjuvant treatment of partial onset epilepsy. carisbamate produces anticonvulsant effects in primary generalized, complex partial and absence-type seizure models, and exhibits neuroprotective and antiepileptogenic proper. Synonyms: JNJ-10234094; JNJ10234094; JNJ10234094; RWJ 333369; RWJ333369; RWJ-333369; YKP-509; YKP-509; YKP-509; Carisbamate. trade name Comfyde. 2-(2-CHLOROPHENYL)-2-HYDROXYETHYL CARBAMATE; Carisbamate; (S)-Carisbamate. Grade: >98%. CAS No. 194085-75-1. Molecular formula: C9H10ClNO3. Mole weight: 215.635.
(S)-CCG-1423
(S)-CCG-1423 is a stereoisomer of CCG-1423, a Rho inhibitor that blocks signaling through myocardin-related transcription factor A (MRTF-A) and serum response factor (SRF). Synonyms: (S)-N-((1-((4-chlorophenyl)amino)-1-oxopropan-2-yl)oxy)-3,5-bis(trifluoromethyl)benzamide. Grade: ≥98%. Molecular formula: C18H13ClF6N2O3. Mole weight: 454.8.
(S)-Ceralasertib
(S)-Ceralasertib is a potent and selective inhibitor of sulfoximine morpholinopyrimidine ATR with excellent preclinical physicochemical and pharmacokinetic (PK) characteristics. Synonyms: (S)-AZD6738; 4-{4-[(3R)-3-Methylmorpholin-4-yl]-6-[1-((S)-S-methylsulfonimidoyl)cyclopropyl]pyrimidin-2-yl}-1H-pyrrolo[2,3-b]pyridine. Grade: ≥95%. CAS No. 1352226-87-9. Molecular formula: C20H24N6O2S. Mole weight: 412.51.
A nonsedating type histamine H1-receptor antagonist. A major metabolite of Hydroxyzine. Pharmacological activity resides primarily in the (R)-isomer. Antihystaminic. Synonyms: (S)-[2-[4-[(4-Chlorophenyl)-phenylmethyl]-1-piperazinyl]ethoxy]acetic Acid Dihydrochloride; (+)-Cetirizine Dihydrochloride; Dextrocetirizine Dihydrochloride. Grade: > 95%. CAS No. 163837-48-7. Molecular formula: C21H25ClN2O3. 2 HCl. Mole weight: 388.90 2 36.46.
(S)-CFI-401870
CFI-401870, an azabicyclo derivative, has been found to be a TTK inhibitor that could be significant in anticancer studies. IC50 < 10 nM. Synonyms: CFI-401870; CFI 401870; CFI401870; N-((R)-cyclopropyl(pyridin-2-yl)methyl)-3-(4-((1R,3R,5S)-3-hydroxy-8-azabicyclo[3.2.1]octan-8-yl)phenyl)-1H-indazole-5-carboxamide. Grade: 98%. CAS No. 1599460-95-3. Molecular formula: C30H31N5O2. Mole weight: 493.61.
(S)-Cinacalcet hydrochloride
(S)-Cinacalcet hydrochloride is an impurity of Cinacalcet, which is a drug that acts as a calcimimetic, and is used to treat secondary hyperparathyroidism (elevated parathyroid hormone levels). Synonyms: ent-Cinacalcet Hydrochloride; (S)-N-(1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine hydrochloride. CAS No. 1217809-88-5. Molecular formula: C22H23ClF3N. Mole weight: 393.88.
(S)-Citadiol hemi-bis-4-toluoyl-D-tartrate
An impurity of Escitalopram. Escitalopram is a selective serotonin reuptake inhibitor (SSRI) used primarily to treat major depressive disorder and generalized anxiety disorder in adults and adolescents aged 12 years and older. Synonyms: Butanedioic acid, 2,3-bis[(4-methylbenzoyl)oxy]-, (2S,3S)-, compd. with 4-[(1S)-4-(dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile (1:2); Benzonitrile, 4-[4-(dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)-, (S)-, (2S,3S)-2,3-bis[(4-methylbenzoyl)oxy]butanedioate (2:1) (salt); (1S)-4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile hemi-(+)-di(p-toluoyl)tartrate; (S)-Citadiol D-DTTA Salt; (-)-4-(4-Dimethylamino)-1-(4-fluorophenyl)-1-(hydroxybuty)-3-hydroxymethyl)-benzonitrile hemi D-(+)-di-p-toloyltartaric acid salt. Grade: ≥95%. CAS No. 128173-53-5. Molecular formula: C20H23FN2O2.1/2C20H18O8. Mole weight: 1071.17.
(S)-Citalopram-d4 Oxalate
(S)-Citalopram-d4 Oxalate, is the labelled analogue of (S)-Citalopram Oxalate, which is an inhibitor of serotonin (5-HT) uptake, and an antidepressant agent. Synonyms: (1S)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile-d4 Ethanedioate; Escitalopram-d4 Oxalate; (S)-(+)-Citalopram-d4 Oxalate; Cipralex. Grade: > 95%. Molecular formula: C22H19FN2O5D4. Mole weight: 418.45.
(S)-Citalopram N-Oxide
(S)-Citalopram N-Oxide is an active metabolite of citalopram, a selective serotonin reuptake inhibitor (SSRI) commonly prescribed as an antidepressant. (S)-Citalopram N-Oxide assists in the research of depression and other related mood disorders by regulating the levels of serotonin, a neurotransmitter in the brain. Synonyms: (S)-1-[3-(Dimethyloxidoamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro -5-isobenzofurancarbonitrile; (S)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile N1-Oxide. Grade: > 95%. CAS No. 917482-45-2. Molecular formula: C20H21FN2O2. Mole weight: 340.39.
(S)-(+)-Clenbuterol
(S)-(+)-Clenbuterol is the (S)-Enantiomer of Clenbuterol and is used as a reagent in the synthesis of pyrazolopyridine derivatives as inhibitors of phosphodiesterase-4 (PDE-IV) and production of tumor necrosis factor-α (TNF-α). Uses: (s)-enantiomer of clenbuterol. substituted phenylethanolamine with β2 sympathomimetic activity. bronchodilator. Synonyms: (αS)-4-Amino-3,5-dichloro-α-[[(1,1-dimethylethyl)amino]methyl]benzenemethanol; (+)-Clenbuterol; (S)-Clenbuterol. Grade: 98%. CAS No. 50499-60-0. Molecular formula: C12H18Cl2N2O. Mole weight: 277.19.
(S)-Cloperastine
(S)-Cloperastine is used in the treatment of chronic non-productive cough. Synonyms: Levocloperastine; Privituss; 1-[2-[(S)-(4-Chlorophenyl)phenylmethoxy]ethyl]piperidine. Grade: > 95%. CAS No. 132301-89-4. Molecular formula: C20H24ClNO. Mole weight: 329.86.
(S)-Cloperastine Fendizoate
(S)-Cloperastine Fendizoate is the salt of (S)-Cloperastine, used in the treatment of chronic non-productive cough. Synonyms: Levocloperastine Fendizoate; 1-[2-[(4-Chlorophenyl)phenylmethoxy]ethyl]-piperidine (-)-, 2-[(6-Hydroxy[1,1'-biphenyl]-3-yl)carbonyl]benzoate; 2-[(6-Hydroxy[1,1'-biphenyl]-3-yl)carbonyl]benzoic Acid Compound With (-)-1-[2-[(4-Chlorophenyl)phenylmethoxy]eth. Grade: > 95%. CAS No. 220329-19-1. Molecular formula: C40H38ClNO5. Mole weight: 648.19.
(S)-(+)-Clopidogrel-d3 sulfate
(S)-(+)-Clopidogrel-d3 is intended for use as an internal standard for the quantification of (S)-(+)-clopidogrel by GC- or LC-MS. Synonyms: methyl-d3 (S)-2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate sulfate. Grade: ≥99% atom D. Molecular formula: C16H13ClD3NO2S·H2SO4. Mole weight: 422.9.
(S)-Cotinine N-Oxide
(S)-Cotinine N-Oxide is a major metabolite of Nicotine in humans. Synonyms: (5S)-1-Methyl-5-(1-oxido-3-pyridinyl)-2-pyrrolidinone; (-)-Cotinine N-oxide; 1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone N-Oxide. Grade: > 95%. CAS No. 36508-80-2. Molecular formula: C10H12N2O2. Mole weight: 192.21.
(S)-CPW 399
(S)-CPW 399 has been found to be a subtype-selective weakly desensitising AMPA agonist. Synonyms: (S)-CPW 399; (S)-CPW399; (S)-CPW-399; (S)-α-Amino-2,3,4,5,6,7-hexahydro-2,4-dioxo-1H-cyclopentapyrimidine-1-propanoic acid. Grade: ≥98% by HPLC. CAS No. 389888-02-2. Molecular formula: C10H13N3O4. Mole weight: 239.23.
(S)-crizotinib
(S)-crizotinib disrupts nucleotide pool homeostasis via MTH1 inhibition, induces an increase in DNA single-strand breaks, and activates DNA repair in human colon carcinoma cells. Synonyms: S-Crizotinib; ent-crizotinib. Grade: >98%. CAS No. 1374356-45-2. Molecular formula: C21H22Cl2FN5O. Mole weight: 450.34.
(S)-Desethyl oxybutynin
(S)-Desethyl oxybutynin is an impurity of (S)-oxybutynin that inhibits muscarinic receptors in bladder smooth muscle and thus prevents the acetylcholine binding. Synonyms: 4-(ethylamino)but-2-ynyl (2S)-2-cyclohexyl-2-hydroxy-2-phenylacetate. CAS No. 181646-98-0. Molecular formula: C20H27NO3. Mole weight: 329.44.
(S)-Desethyl Oxybutynin HCl
An impurity of Oxybutynin which is an inhibitor of proliferation and supresses gene expression in bladder smooth muscle cells. Synonyms: (S)-N-Desethyl Oxybutynin Hydrochloride; (αS)-α-Cyclohexyl-α-hydroxybenzeneacetic Acid 4-(Ethylamino)-2-butyn-1-yl Ester Hydrochloride. Grade: > 95%. CAS No. 181647-14-3. Molecular formula: C20H27NO3.HCl. Mole weight: 370.93.
(S)-Desmethylcitalopram
(S)-Desmethylcitalopram is a metabolite of Citalopram, which is an inhibitor of serotonin (5-HT) uptake used as an antidepressant. Synonyms: 5-Isobenzofurancarbonitrile, 1-(4-fluorophenyl)-1,3-dihydro-1-[3-(methylamino)propyl]-, (1S)-; (1S)-1-(4-Fluorophenyl)-1,3-dihydro-1-[3-(methylamino)propyl]-5-isobenzofurancarbonitrile; 5-Isobenzofurancarbonitrile, 1-(4-fluorophenyl)-1,3-dihydro-1-[3-(methylamino)propyl]-, (S)-; (S)-(+)-N-Demethylcitalopram; (S)-1-(3-Methylaminopropyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile; S-Desmethylcitalopram. Grade: ≥95%. CAS No. 144025-14-9. Molecular formula: C19H19FN2O. Mole weight: 310.37.
(S)-Desmethyl Citalopram-d4 Oxalate
(S)-Desmethyl Citalopram-d4 Oxalate is the labelled analogue of (S)-Citalopram Oxalate, which is an inhibitor of serotonin (5-HT) uptake, and an antidepressant agent. Grade: 98% HPLC. Molecular formula: C19H15FN2OD4·C2H2O4. Mole weight: 404.44.
(S)-Desmethyl Rabeprazole Sodium Salt
S enantiomer of Desmethyl Rabeprazole Sodium Salt. Desmethyl Rabeprazole Sodium Salt is a derivative of Rabeprazole. Rabeprazole is proton pump inhibitor as an antiulcer drug. Grade: > 95%. Molecular formula: C17H18N3O3S.Na. Mole weight: 367.41.
(S)-Didemethyl Citalopram Hydrochloride
(S)-Didemethyl Citalopram Hydrochloride is a metabolite of Citalopram, an inhibitor of serotonin (5-HT) uptake. It is used as an antidepressant. Synonyms: (1S)-1-(3-Aminopropyl)-1-(4-fluorophenyl)-1,3-dihydro- 5-isobenzofurancarbonitrile Hydrochloride; (+)-(S)-1-(3-Aminopropyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile Hydrochloride; (S)-Didesmethylcitalopram Hydrochloride. Grade: > 95%. Molecular formula: C18H18ClFN2O. Mole weight: 332.8.
(S)-(+)-Dimethindene
(S)-(+)-Dimethindene is a subtype-selective mAChR M2 antagonist and histamine H1 receptor antagonist. Synonyms: 1H-Indene-2-ethanamine, N,N-dimethyl-3-[(1S)-1-(2-pyridinyl)ethyl]-; 1H-Indene-2-ethanamine, N,N-dimethyl-3-[1-(2-pyridinyl)ethyl]-, (S)-; N,N-Dimethyl-3-[(1S)-1-(2-pyridinyl)ethyl]-1H-indene-2-ethanamine; (+)-Dimethindene; (S)-Dimethindene; (S)-N,N-dimethyl-2-(3-(1-(pyridin-2-yl)ethyl)-1H-inden-2-yl)ethan-1-amine. Grade: ≥95%. CAS No. 121367-05-3. Molecular formula: C20H24N2. Mole weight: 292.42.
(S)-(+)-Dimethindene Maleate
The maleate salt form of (S)-(+)-Dimethindene, which has been found to be a subtype-selective mAChR M2 antagonist and histamine H1 receptor antagonist. Synonyms: 1H-Indene-2-ethanamine, N,N-dimethyl-3-[(1S)-1-(2-pyridinyl)ethyl]-, (2Z)-2-butenedioate (1:1); 1H-Indene-2-ethanamine, N,N-dimethyl-3-[1-(2-pyridinyl)ethyl]-, (+)-, (Z)-2-butenedioate (1:1); N,N-Dimethyl-3-[(1S)-1-(2-pyridinyl)ethyl]-1H-indene-2-ethanamine maleate; (+)-Dimethindene maleate; (S)-Dimethindene maleate; (S)-N,N-dimethyl-2-(3-(1-(pyridin-2-yl)ethyl)-1H-inden-2-yl)ethan-1-amine maleate. Grade: ≥99% by HPLC. CAS No. 136152-65-3. Molecular formula: C20H24N2.C4H4O4. Mole weight: 408.50.
(S)-dimethyl 2-(4-(4-oxobutyl)benzamido)pentanedioate is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: Pemetrexed Impurity 10. CAS No. 1081974-98-2. Molecular formula: C18H23NO6. Mole weight: 349.38.
(S)-DMT-glycidol-A(Bz)
(S)-DMT-glycidol-A(Bz), a critical element in the creation of potential anticancer drugs, has proven effective by restraining tumor progression and stimulating apoptosis in different cancer cell lines such as those in the breast, lung, and pancreas. Its dynamic efficacy in inhibiting specific enzyme pathways at the core of cancer cell growth and survival establish it as a highly viable candidate for innovative cancer treatment measures with significant potential. Synonyms: Benzamide, N-[9-[(2S)-3-[bis(4-methoxyphenyl)phenylmethoxy]-2-hydroxypropyl]-9H-purin-6-yl]-; (S)-9-[3-(4,4'-Dimethoxytrityloxy)-2-hydroxypropyl]-N6-benzoyladenine; 3'-O-Bis(p-methoxyphenyl)phenylmethyl-9-(S)-(2,3-dihydroxypropyl)-N6-benzoyladenine; (S)-N-(9-(3-(Bis(4-methoxyphenyl)(phenyl)methoxy)-2-hydroxypropyl)-9h-purin-6-yl)benzamide. Grade: ≥95%. CAS No. 115196-70-8. Molecular formula: C36H33N5O5. Mole weight: 615.68.
(S)-DMT-glycidol-C(Bz)
(S)-DMT-glycidol-C(Bz), a vital pharmaceutical intermediate, finds its usage in the synthesis of an array of drugs. It is particularly deployed in antineoplastic agent formulations such as taxanes and camptothecin analogues. The role of (S)-DMT-glycidol-C(Bz) cannot be understated as it plays a crucial role in the production of drugs catering to cancer and curing other diseases. Synonyms: (S)-1-[3-(4,4'-Dimethoxytrityloxy)-2-hydroxypropyl]-N4-benzoylcytosine. Grade: ≥95%. CAS No. 127757-40-8. Molecular formula: C35H33N3O6. Mole weight: 591.65.
(S)-DMT-glycidol-T
(S)-DMT-glycidol-T is a potent biomedicine utilized to research various diseases. It demonstrates promising antimicrobial activity against multiple drug-resistant bacteria, making it a valuable compound for combating infections. Synonyms: (S)-1-[3-(4,4'-Dimethoxytrityloxy)-2-hydroxypropyl]thymine; (S)-1-(3-(Bis(4-methoxyphenyl)(phenyl)methoxy)-2-hydroxypropyl)-5-methylpyrimidine-2,4(1H,3H)-dione; 1-{(2S)-3-[Bis(4-methoxyphenyl)(phenyl)methoxy]-2-hydroxypropyl}-5-methyl-2,4(1H,3H)-pyrimidinedione. Grade: ≥95%. CAS No. 168332-12-5. Molecular formula: C29H30N2O6. Mole weight: 502.56.
(S)-DMT-glycidol-uracil
(S)-DMT-glycidol-uracil, an emerging biomedicine, exhibits promising prospects in combatting specific cancer types such as ovarian and endometrial cancer via the inhibition of cancerous cells and induction of apoptosis. Its specificity towards cancer cells significantly reduces the likelihood of injuring healthy cells, making it a viable alternative for cancer treatment. Synonyms: 2,4(1H,3H)-Pyrimidinedione, 1-[(2S)-3-[bis(4-methoxyphenyl)phenylmethoxy]-2-hydroxypropyl]-; (S)-1-[3-(4,4'-Dimethoxy trityloxy)-2-hydroxypropyl]uracil; 1-{(S)-3-[Bis-(4-methoxy-phenyl)-phenyl-methoxy]-2-hydroxy-propyl}-1H-pyrimidine-2,4-dione. Grade: ≥95%. CAS No. 494784-12-2. Molecular formula: C28H28N2O6. Mole weight: 488.53.
(S)-Dolaphenine hydrochloride
(S)-Dolaphenine hydrochloride is a useful componet for compound synthesis. Synonyms: (S)-Dolaphenine hydrochloride. Grade: >98%. CAS No. 135383-60-7. Molecular formula: C11H13ClN2S. Mole weight: 240.75.
(S)-Duloxetine Phtalamide
(S)-Duloxetine Phthalamide is an impurity of (S)-Duloxetine present with enteric polymer hydroxypropylmethylcellulose phthalate (HPMCP) in dosage formulations. Synonyms: 2-[[Methyl[(3S)-3-(1-naphthalenyloxy)-3-(2-thienyl)propyl]amino]carbonyl]benzoic Acid. Grade: > 95%. CAS No. 199191-67-8. Molecular formula: C26H23NO4S. Mole weight: 445.53.
(S,E)-2-(3-(1-((tert-Butyldimethylsilyl)oxy)-3-(2-(1-((tert-butyldimethylsilyl)oxy)vinyl)phenyl)propyl)styryl)-7-chloroquinoline is an impurity of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Molecular formula: C40H52ClN2Si2. Mole weight: 652.48.
An impurity of Efinaconazole, a triazole antifungal approved to treat fungal infections of the toenails as a topical solution. Synonyms: (2S,3E)-3-(2,4-Difluorophenyl)-4-(1H-1,2,4-triazol-1-yl)but-3-en-2-ol. Grade: 99%. CAS No. 2223129-33-5. Molecular formula: C12H11F2N3O. Mole weight: 251.24.
An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: Afatinib Impurity 18. Grade: ≥95%. CAS No. 2413212-25-4. Molecular formula: C24H26FN5O3. Mole weight: 451.50.
(S,E)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-5-hydroxyhept-2-enoic acid calcium(II) is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. CAS No. 1659317-57-3. Molecular formula: C66H64CaF2N4O8. Mole weight: 1119.33.
An impurity of Pramipexole which is an agonist of dopamine receptor D2, D3 and D4, especially used as D2-receptor agonist. Synonyms: rac N-Propyl-2-cyanimidopyrrolidine-5-acetic Acid Methyl Ester; Pramipexole Impurity 16. Grade: 99%. CAS No. 1373869-91-0. Molecular formula: C11H17N3O2. Mole weight: 223.27.
An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: 4-(Dimethylamino)but-2-enamide, (S,E)-N-(4-((3,4-difluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-; Afatinib Difluoro Analog; Afatinib Impurity SF. Grade: ≥95%. CAS No. 2223677-62-9. Molecular formula: C24H25F2N5O3. Mole weight: 469.48.