BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
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TDP-a-D-glucose ammonium salt
TDP-a-D-glucose ammonium salt, a versatile reagent for research, elucidates the intricacies of glycosylation processes and the carbohydrate metabolism systems. Its multifaceted applications extend to investigating correlations between these processes and an array of debilitating health conditions, including but not limited to cancer, diabetes, and neurodegenerative disorders. Furthermore, it serves as a substrate in the biosynthesis pathways of bacterial extracellular polymeric substances, adding to its already impressive repertoire of uses. Molecular formula: C16H32N4O17P2. Mole weight: 614.39.
TDP-b-L-rhamnose ammonium salt
TDP-b-L-rhamnose ammonium salt is a key intermediate product utilized in the synthesis of rhamnose-containing antibiotics. This compound is essential in the production of drugs like the aminoglycoside antibiotics; neomycin, paromomycin, and lividomycin. Its main role is to catalyze the formation of the rhamnose sugar moiety in these antibiotics, essential for their antibiotic activity. Molecular formula: C16H32N4O16P2. Mole weight: 598.39.
TDSP5
TDSP5, a low molecular weight protamine as a nontoxic heparin/low molecular weight heparin antidote, is a homogeneous 1880-d peptide fragment derived directly from protamine by enzymatic digestion of protamine with thermolysin. TDSP5 neutralizes the anticoagulant effects of heparin and commercial low molecular-weight heparin preparations. TDSP5 shows significantly reduced crossreactivity toward mouse sera containing antiprotamine antibodies. TDSP5 exhibits a decrease in its potential in activating the complement system. Synonyms: LMWP-TDSP5; Low molecular weight protamine-TDSP5.
Telbivudine
Telbivudine is an antiviral drug used in the treatment of hepatitis B infection. It is marketed by Swiss pharmaceutical company Novartis under the trade names Sebivo (Europe) and Tyzeka (United States). Clinical trials have shown it to be significantly more effective than lamivudine or adefovir, and less likely to cause resistance. Uses: Antiviral agents. Synonyms: LDT 600; LD-T600; LDT600; Telbivudine; Tyzeka; Epavudine. Grades: 98%. CAS No. 3424-98-4. Molecular formula: C10H14N2O5. Mole weight: 242.23.
Telomerare Reverse Transcriptase (hTRT) (653-661)
Human telomerase reverse transcriptase is a catalytic subunit of the enzyme telomerase, which, together with the telomerase RNA component (TERC), comprises the most important unit of the telomerase complex. Synonyms: hTRT (653-661).
tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate (CAS# 112741-49-8) is a reactant used in the preparation of (-)-Jorumycin, (-)-Renieramycin G, 3-epi-Jorumycin, and 3-epi-Renieramycin G and collagen cross-link pyridinolines. Synonyms: (5S,6R)-N-Boc-5,6-diphenyl-2-morpholinone. Grades: 98 %. CAS No. 112741-49-8. Molecular formula: C21H23NO4. Mole weight: 353.4.
tert-Butyl N-{9-[(3aR,4R,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyl-tetrahydro-2H-furo[3,4-d][1,3]dioxol-4-yl]-9H-purin-6-yl}-N-[(tert-butoxy)carbonyl]carbamate (CAS# 1152172-19-4) is used as a reactant in the synthesis of siderophore biosynthesis inhibitors for M. tuberculosis. Synonyms: N,N-bis[(1,1-dimethylethoxy)carbonyl]-2',3'-O-(1-methylethylidene)-adenosine. CAS No. 1152172-19-4. Molecular formula: C23H33N5O8. Mole weight: 507.54.
Tertiapin-Q
Tertiapin-Q, a derivative of the bee venom toxin tertiapin, is a high affinity blocker of inward-rectifier K+ channels. Tertiapin-Q binds to ROMK1 (Kir1.1) and GIRK1/4 (Kir3.1/3.4) channels (Ki = 1.3 and 13.3 nM, respectively) with selectivity over Kir2.1 channels. Synonyms: L-Lysinamide, L-alanyl-L-leucyl-L-cysteinyl-L-asparaginyl-L-cysteinyl-L-asparaginyl-L-arginyl-L-isoleucyl-L-isoleucyl-L-isoleucyl-L-prolyl-L-histidyl-L-glutaminyl-L-cysteinyl-L-tryptophyl-L-lysyl-L-lysyl-L-cysteinylglycyl-L-lysyl-, cyclic (3?14),(5?18)-bis(disulfide); Tertiapin Q; L-alanyl-L-leucyl-L-cysteinyl-L-asparagyl-L-cysteinyl-L-asparagyl-L-arginyl-L-isoleucyl-L-isoleucyl-L-isoleucyl-L-prolyl-L-histidyl-L-glutaminyl-L-cysteinyl-L-tryptophyl-L-lysyl-L-lysyl-L-cysteinyl-glycyl-L-lysyl-L-lysinamide (3->14),(5->18)-bis(disulfide); H-Ala-Leu-Cys-Asn-Cys-Asn-Arg-Ile-Ile-Ile-Pro-His-Gln-Cys-Trp-Lys-Lys-Cys-Gly-Lys-Lys-NH2 (Disulfide bridge: Cys3-Cys14, Cys5-Cys18). Grades: ≥95%. CAS No. 910044-56-3. Molecular formula: C106H175N35O24S4. Mole weight: 2452.01.
Tetrabenzyl Thymidine-3',5'-diphosphate
Tetrabenzyl Thymidine-3',5'-diphosphate is a crucial compound widely used in biomedicine. With its ability to inhibit DNA polymerase, it plays a significant role as a potential antiviral drug, specifically in the treatment of viral diseases such as HIV and hepatitis. Its binding affinity and specificity make it an essential tool in understanding viral replication mechanisms and developing effective therapeutic interventions. Molecular formula: C38H40N2O11P2. Mole weight: 762.68.
Tetracaine EP Impurity A
4-Aminobenzoic acid, also known as PABA, is a B vitamin derivative with UV absorption and antifibrotic properties. 4-Aminobenzoic acid can be generated by some intestinal bacteria, and acts as an intermediate in the synthesis of folate (vitamin B9). It is used in the treatment of fibrotic skin disorder, also can be used as a supplement for fatigue, irritability, depression, etc. Nutritional supplement in health care products. Synonyms: Benzocaine EP Impurity G; p-Aminobenzoic Acid; Bacterial Vitamin H1; p-Carboxyaniline; p-Carboxyphenylamine; Actipol; Amben; PABA; Pabacyd; Pabafilm; Trichochromogenic Factor; Vitamin BX; Vitamin H'. Grades: ≥98.5% by assay. CAS No. 150-13-0. Molecular formula: C7H7NO2. Mole weight: 137.14.
Texas Red-5-dUTP Triammonium Monosodium Salt
As a fluorescence-labelled nucleotide analog, Texas Red-5-dUTP is used diagnostically for detection of rearranged SS18 in formalin-fixed, paraffin-embedded synovial sarcoma. Synonyms: 9-[4-[[[3-[1-[2-Deoxy-5-O-[hydroxy[[hydroxy (phosphonooxy) phosphinyl]oxy]phosphinyl]-β -D-erythro-pentofuranosyl]-1, 2, 3, 4-tetrahydro-2, 4-dioxo-5-pyrimidinyl]-2-propynyl]amino]sulfonyl]-2-sulfophenyl]-2, 3, 6, 7, 12, 13, 16, 17-octahydro-1H, 5H, 11H, 15H-xantheno[2, 3, 4-ij: 5, 6, 7-i'j']diquinolizin-18-ium Inner Salt Triammonium Monosodium Salt. Grades: 85%. Molecular formula: C43H54N8NaO20P3S2. Mole weight: 1182.97.
Tezacitabine
Tezacitabine is a synthetic purine nucleoside analogue with potential antineoplastic activity. Phosphorylated by cellular kinases, tezacitabine is converted into its active diphosphate and triphosphate metabolites. Tezacitabine diphosphate binds to and irreversibly inhibits the activity of the enzyme ribonucleotide reductase (RNR), which may result in the inhibition of DNA synthesis in tumor cells and tumor cell apoptosis. Tezacitabine triphosphate acts as a substrate for DNA polymerase, further compromising DNA replication. This agent is relatively resistant to metabolic deactivation by cytidine deaminase. RNR catalyzes the conversion of ribonucleoside 5'-diphosphates to deoxyribonucleoside 5'-diphosphates necessary for DNA synthesis and is overexpressed in many tumor types. Uses: Enzyme inhibitors. Synonyms: MDL 101731; FMdC; KW 2331; MDL 101731; KW2331; MDL101731; Tezacitabine; MDL 101,731; FMdC. CAS No. 130306-02-4. Molecular formula: C10H12FN3O4. Mole weight: 257.221.
TFA-aa-dC
TFA-aa-dC, a profound biomedicine marvel, takes center stage in combating select malignancies. Captivatingly, this ingenious trifluoroacetic acid derivative, bearing resemblance to adenosine, displays a potent affinity for cancerous cells. Through its remarkable prowess, it exhibits profound inhibitory effects on the relentless proliferation of these abhorrent entities, while also inducing their inevitable demise through apoptosis. Notably, within the realms of scientific exploration, TFA-aa-dC aptly finds its niche as a vital tool for comprehending the intricate fabric of cancer biology and facilitating the development of groundbreaking therapeutic approaches. Synonyms: 5-TFA-aa-2'-Deoxycytidine; 5-[(E)-3-(Trifluoroacetylamino)-1-propenyl]-2'-deoxycytidine; 5-TFA-aa-dC; Cytidine, 2'-deoxy-5-[3-[(2,2,2-trifluoroacetyl)amino]-1-propen-1-yl]-; 2'-Deoxy-5-{(1E)-3-[(trifluoroacetyl)amino]-1-propen-1-yl}cytidine. Grades: ≥98% by HPLC. CAS No. 96102-27-1. Molecular formula: C14H17F3N4O5. Mole weight: 378.30.
TFA-aa-dUPhosphoramidite
TFA-aa-dUPhosphoramidite is a crucial compound extensively used in the biomedical industry. This phosphoramidite derivative plays a vital role in synthesis for the generation of modified DNA/RNA sequences. It aids in the production of advanced nucleotide analogs applicable in diverse therapeutic areas, including antiviral and anticancer drug research and development. Molecular formula: C44H51N5O9P. Mole weight: 824.88.
TFA-aha-dC
TFA-aha-dC is a potent nucleoside containing trifluoroacetic acid (TFA). This product plays a crucial role as a protected nucleoside during solid-phase DNA synthesis. It is commonly utilized in research involving the study of DNA structure, epigenetics and the development of therapeutic drugs targeting cancer and viral diseases. Molecular formula: C20H28F3N5O6. Mole weight: 491.46.
TFA-ap-dC
TFA-ap-dC, a nucleoside analog, is a potent agent utilized in oligonucleotide synthesis for antisense therapy. With impressive efficacy in combating viral infections and cancer by inhibiting gene expression, TFA-ap-dC stands out with unparalleled stability and compatibility with solid-phase synthesis protocols, thus vastly benefitting biomedicine industries. Synonyms: 5-TFA-ap-dC; 5-TFA-ap-2'-Deoxycytidine. CAS No. 115899-38-2. Molecular formula: C14H15F3N4O5. Mole weight: 376.29.
TFA-ap-dU
2'-Deoxy-5-[3-[(2,2,2-trifluoroacetyl)amino]-1-propyn-1-yl]uridine is an intermediate in the synthesis of fluorescent labeling compounds of cyclooctyne-modified deoxyuridine triphosphates in DNA. Synonyms: 5-TFA-ap-2'-Deoxyuridine; Uridine, 2'-deoxy-5-[3-[(trifluoroacetyl)amino]-1-propynyl]-. Grades: 96%. CAS No. 115899-40-6. Molecular formula: C14H14F3N3O6. Mole weight: 377.27.
TFFYGGSRGKRNNFKTEEYC
TFFYGGSRGKRNNFKTEEYC is a peptide, which can be used for glioma targeted therapy. Grades: 98%. CAS No. 906480-09-9. Molecular formula: C107H154N30O32S. Mole weight: 2404.6.
TfR-T12
TfR-T12 is a BBB-penetrated transferrin receptor (TfR) binding peptide. CAS No. 344618-30-0. Molecular formula: C71H99N19O15S. Mole weight: 1490.73.
TGF-beta receptor type-2 (131-139)
TGF-beta receptor type-2 (131-139) is a truncated fragment of TGF-beta receptor type-2. TGF-beta receptor type-2 is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with TGF-beta receptor type-1, and binds TGF-beta. Synonyms: Transforming Growth Factor Beta Receptor 2 (131-139); TGF-Beta Type II Receptor (131-139).
Thiazole Orange NHS Ester
Thiazole Orange NHS Ester is a fluorescent labeling reagent used in biomedical research to selectively label DNA and RNA in living cells. It has also been used to monitor the function of lysosomes and to identify amyloid-beta plaques in Alzheimer's disease. Synonyms: N-(5-carboxypentyl)-2-[(1,4-dihydro-1-methylquinolin-4-ylidene)methyl]benzothiazol-3-ium chloride N-hydroxysuccinimide ester. Molecular formula: C28H28ClN3O4S. Mole weight: 538.06.
Thieno-CTP
Thieno-CTP, an innovative nucleotide analog, thwarts the replication of RNA viruses such as influenza or respiratory syncytial virus by targeting the RNA polymerase enzyme essential for their propagation. With numerous potential therapeutic values, Thieno-CTP assumes an indispensable role in the management of viral respiratory infections. Synonyms: Thienocytidine-5'-Triphosphate; thCTP; 4-Aminothieno[3,4-d]pyrimidin-2(1H)-one 1-β-D-ribofuranoside 5'-Triphosphate. Grades: ≥95% by AX-HPLC. Molecular formula: C11H16N3O14P3S. Mole weight: 539.25.
Thieno-UTP
Thieno-UTP is an extensively utilized compound, standing as a pivotal component for drug synthesis. Its indispensable role encompasses the research of medical afflictions, comprising cancer, viral infections, along with neurological disorders. Synonyms: Thienouridine-5'-Triphosphate; thUTP; Thieno[3,4-d]pyrimidine-ribonucleoside-5'-Triphosphate. Grades: ≥95% by AX-HPLC. Molecular formula: C11H15N2O15P3. Mole weight: 540.2.
Thiol-Modifier C3 S-S CE Phosphoramidite
Thiol-Modifier C3 S-S CE Phosphoramidite, a highly esteemed reagent, holds immense importance in modifying thiol groups for bioconjugation. This essential tool's significance lies in peptide and oligonucleotide synthesis for diseases such as cancer, HIV, and Alzheimer's disease. Moreover, Thiol-Modifier C3 S-S CE Phosphoramidite's utilization in drug discovery research facilitates the development of novel therapeutic agents. Undoubtedly, Thiol-Modifier C3 S-S CE Phosphoramidite plays a crucial role in biomedicine research and development. Grades: >95% by HPLC. Molecular formula: C36H49N2O5PS2. Mole weight: 684.89.
Thiol-Modifier C6 S-S
BOC RNA provides the most complete Thiol-Modifier C6 S-S, which can be used to introduce 3'- or 5'-thiol bonds. Synonyms: 1-O-Dimethoxytrityl-hexyl-disulfide, 1'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Thiol-Modifier C6 S-S CE Phosphoramidite. Grades: >95% by HPLC. CAS No. 148254-21-1. Molecular formula: C42H61N2O5S2P. Mole weight: 769.05.
Thiostrepton
Thiostrepton, a kind of natural peptide thiazole antibiotic, has been found to be effective in restraining the protein synthesis and could also influence the cell cycle and lead to apoptosis in breast cancer cells. It is also resistant to gram-positive bacteria and mycobacteria. Uses: Thiostrepton is a kind of natural peptide thiazole antibiotic that has been found to be effective in restraining the protein synthesis and could also influence the cell cycle and leat to apoptosis in breast cancer cells. Synonyms: Bryamycin; Thiactin. Grades: 98%. CAS No. 1393-48-2. Molecular formula: C72H85N19O18S5. Mole weight: 1664.9.
Thymidine-2',3'-didehydro-5'-phosphonyl-L-alanine Ditriethylamine Salt
As a metabolite of Stampidine, Thymidine-2',3'-didehydro-5'-phosphonyl-L-alanine Ditriethylamine Salt is an antiretroviral (ARV) which is a nucleoside reverse transcriptase inhibitor (NRTI) as a candidate for preexposure prophylaxis against sexually transmitted HIV/AIDS. Synonyms: Ala-d4T-MP Ditriethylamine Salt; (2R) -2- ( (Hydroxy ( ( (2S, 5R) -5- (5-methyl-2, 4-dioxo-3, 4-dihydropyrimidin-1 (2H) -yl) -2, 5-dihydrofuran-2-yl) methoxy) phosphoryl) amino) propanoic Acid Ditriethylamine Salt. Molecular formula: C25H48N5O8P. Mole weight: 577.65.
Thymidine 3',5'-Diphosphate Disodium Salt
As a metabolite of Thymidine, Thymidine-3',5'-diphosphate (pTp) can be used as a model compound for studies of reactions leading to strand breaks in DNA. Synonyms: 3'-Thymidylic Acid 5'-(Dihydrogen Phosphate) Disodium Salt; 2'-Deoxythymidine 3',5'-Diphosphate Disodium; 3',5'-Bisphospho-2'-deoxythymidine Disodium; 3',5'-TDP Disodium; Deoxythymidine 3',5'-Diphosphate Disodium; PTP Disodium; Thymidine 3',5'-Bisphosphate Disodium. Grades: 95%. CAS No. 386229-77-2. Molecular formula: C10H14N2Na2O11P2. Mole weight: 446.15.
Thymidine-3',5'-tetrabenzyldiphosphate
Thymidine-3',5'-tetrabenzyldiphosphate is a pivotal compound extensively utilized assuming a crucial role in the investigative study of DNA synthesis and replication. It serves as an invaluable substrate analogue for the meticulous examination of numerous enzymes intricately involved in DNA metabolism. Synonyms: Tetrabenzyl-D-thymidine-3',5'-diphosphate; D-Thymidine 3',5'-tetrabenzyldiphosphate. Molecular formula: C38H40N2O11P2. Mole weight: 762.68.
Thymidine 3'-O-L-valinyl ester
Thymidine-5'-diphosphate-2-deoxy-D-glucose disodium salt
Thymidine-5'-diphosphate-2-deoxy-D-glucose disodium salt is an indispensable compound extensively employed within the biomedical field, serving as a pivotal precursor in diverse biological processes pertaining to DNA synthesis. It aids in nucleoside metabolism disorder research, mitigation of viral infections and development of cancer-affiliated therapeutics. Molecular formula: C16H24N2O15P2Na2. Mole weight: 592.29.
Thymidine-5'-diphosphate-4-keto-6-deoxy-D-glucose disodium salt
Thymidine-5'-diphosphate-4-keto-6-deoxy-D-glucose disodium salt is a consequential molecular compound extensively embraced in the realm of biomedical investigation, manifesting itself as a pivotal instrument in the R&D of novel antiviral drugs targeting afflictions like HIV and herpes. Grades: ≥ 85% (HPLC). CAS No. 16752-71-9. Molecular formula: C16H22N2O15P2Na2. Mole weight: 590.28.
Thymidine-5'-diphosphate-6-deoxy-D-allose
Thymidine-5'-diphosphate-b-L-fucose
Thymidine-5'-diphosphate-b-L-fucose is a pivotal compound within the realm of glycobiology research, acting as an invaluable substrate for pivotal fucosylation-related enzymes.It seamlessly facilitates extensive exploration of fucosylated compound biosynthesis, fucosyltransferase functionalities and the intricate implications surrounding pathologies associated with fucose-deficient glycoproteins. Synonyms: TDP-Fucose.
Thymidine 5'-Monophosphate Disodium Salt Hydrate
A nucleoside monophosphate derived from phosphorylation of Thymidine, Which is converted to Thymidine diphosphate by Thymidylate kinase (TMPK), and it's a nucleoside monophosphate kinase. It's also a constituent of Deoxyribonucleic Acid. Synonyms: 5'-Thymidylic Acid Disodium Salt Hydrate; Disodium 5'-dTMP Hydrate; Disodium TMP Hydrate. Grades: 97%. Molecular formula: C10H13N2Na2O8P xH2O. Mole weight: 366.17.
Thymidine-5'-O-(1-thiotriphosphate) lithium salt
Thymidine-5'-O-(1-thiotriphosphate) lithium salt is a valuable compound widely utilized in the biomedical industry serving as a crucial component in numerous biochemical studies, specifically in the fields of DNA sequencing, nucleic acid labeling and various molecular biology techniques. This product plays a vital role in studying DNA replication and repair mechanisms, gene expression and exploring therapeutic targets for diseases like cancer and genetic disorders. Synonyms: a-Thio-TTP. Grades: ≥ 98% (HPLC). Molecular formula: C10H17N2O13P3S·xLi. Mole weight: 498.23 (free acid).
5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2-thiothymidine, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a vital chemical compound used to synthesis modified nucleosides and nucleotides. It is well-suited for nucleic acid exploration, specifically the research of potential antiviral drugs and nucleic acid-based therapeutics. Synonyms: Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2-thio-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI). CAS No. 125258-63-1. Molecular formula: C40H49N4O7PS. Mole weight: 760.88.
Thymidine 5'-triphosphate-3'-monophosphate
Thymidine 5'-triphosphate-3'-monophosphate, renowned for its indispensable role in DNA synthesis and DNA-based applications, assumes a paramount position within the biomedical sector. Revered as a pivotal precursor of DNA, this product proficiently facilitates a myriad of molecular biology techniques, including but not limited to PCR amplification, DNA sequencing, and cloning. Furthermore, it engenders invaluable assistance in unraveling the complexities of DNA replication, repair, and transcription, thereby contributing significantly to the realm of genetic disease and cancer investigations and therapeutics. CAS No. 1015762-49-8. Molecular formula: C10H18N2O17P4. Mole weight: 562.15.
Thymidine 5'-triphosphate lithium salt
Thymidine 5'-triphosphate lithium salt is an indispensable compound widely employed, holding immense significance in diverse applications for studying viral infections, genetic anomalies and neoplastic ailments. This paramount component assumes the role of a nucleotide foundational unit, indispensably participating in the replication and mending mechanisms of DNA. Synonyms: dTTP Li. Grades: ≥ 99% (HPLC). Molecular formula: C10H17N2O14P3·xLi. Mole weight: 482.17 (free acid).
Thymidine-5'-triphosphate sodium salt
dTTP could be used in the studies of DNA labeling reactions, polymerase chain reaction and sequencing/cycle sequencing analysis. Synonyms: 2'-Deoxythymidine-5'-triphosphate trisodium salt; dTTP trisodium salt; Thymidine-5'-triphosphoric acid trisodium salt; sodium ((2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl hydrogentriphosphate; Thymidine 5'-(Tetrahydrogen Triphosphate) Sodium Salt. Grades: ≥95% by HPLC. CAS No. 27821-54-1. Molecular formula: C10H14N2O14P3.3Na. Mole weight: 548.11.
Thymidylyl-(3'-5')-2'-deoxyadenosine
Thymidylyl-(3'-5')-2'-deoxyadenosine is an indispensable constituent harnessed by the biomedical realm assuming myriad roles encapsulating the scientific exploration of DNA's intricate framework and operations. Furthermore, its application prospects encompass developing therapeutic modalities aimed at ameliorating cancer, studying viral invasions and studying genetic aberrations. Synonyms: 3'-O-(2'-Deoxy-5'-adenylyl)thymidine; dTpdA DNA Dinucleotide (5'-3'). Grades: ≥95% by AX-HPLC. Molecular formula: C20H26N7O10P. Mole weight: 555.40.
Thymidylyl-(3',5')-2'-deoxyguanosine
Thymidylyl-(3',5')-2'-deoxyguanosine, a vital biochemical, is extensively employed in biomedical research as a fundamental substrate for enzymes implicated in DNA synthesis, repair, and recombination. Scientists also employ it to fashion innovative antiviral drugs while fighting hard against the scourge of breast, colon, and lung cancer. Its versatile utility makes it an indispensable component of the modern biomedical arsenal. Synonyms: dTpdG DNA Dinucleotide (5'-3'); d(Tpg); Thymidylyl phosphate deoxyguanosine. Grades: ≥95% by AX-HPLC. CAS No. 4251-20-1. Molecular formula: C20H26N7O11P. Mole weight: 571.40.
Thymidylyl-(3'-5')-deoxycytidine
Thymidylyl-(3'-5')-deoxycytidine, the indispensable nucleotide within the burgeoning biomedical industry, plays an elemental role in the intricate processes of DNA and RNA synthesis. Its paramount significance transpires during cell division and the sacrosanct realm of genetic replication. With extensive adoption within multifarious realms of research studies and pharmaceutical applications, this prodigious entity burgeons with its invaluable contribution towards DNA synthesis, repair, and replication. Synonyms: dTpdC DNA Dinucleotide (5'-3'); Thymidylyl-3',5',2'-deoxycytidine; 5'-d[TC]-3'; dTpdC. Grades: ≥95% by AX-HPLC. CAS No. 5178-19-8. Molecular formula: C19H26N5O11P. Mole weight: 531.40.
Thymidylyl-3'-5'-thymidine ammonium salt
Thymidylyl-3'-5'-thymidine ammonium salt is a vital reagent in biomedical research. It plays a crucial role in the development of therapies targeting DNA synthesis-related disorders, including certain genetic diseases and cancer. This product facilitates the investigation of nucleotide metabolism and enables the design of innovative drugs aimed at modulating DNA replication and repair mechanisms. Synonyms: TpT; D-Thymidylyl-3'-5'-thymidine ammonium salt. Grades: ≥ 98% (HPLC). CAS No. 1969-54-6. Molecular formula: C20H27N4O12P·NH3. Mole weight: 563.45.
Thymosin b4 (16-38)
Thymosin b4 (16-38) is a fragment of Thymosin beta-4, which is a protein encoded by the TMSB4X gene in humans. CAS No. 113318-05-1. Molecular formula: C118H204N32O41. Mole weight: 2727.06.
Thymus factor X
Thymus factor X, an aqueous extract from the thymus of juvenile calf, is a natural stimulator of lymphocyte function. Synonyms: TFX-Jelfa. Grades: ≥98%. CAS No. 78310-77-7.
TIP 39, Tuberoinfundibular Neuropeptide
It is a neuropeptide and parathyroid hormone 2 receptor (PTH2R) agonist. Synonyms: Ser-Leu-Ala-Leu-Ala-Asp-Asp-Ala-Ala-Phe-Arg-Glu-Arg-Ala-Arg-Leu-Leu-Ala-Ala-Leu-Glu-Arg-Arg-His-Trp-Leu-Asn-Ser-Tyr-Met-His-Lys-Leu-Leu-Val-Leu-Asp-Ala-Pro; TIP 39 (39 mer); L-seryl-L-leucyl-L-alanyl-L-leucyl-L-alanyl-L-alpha-aspartyl-L-alpha-aspartyl-L-alanyl-L-alanyl-L-phenylalanyl-L-arginyl-L-alpha-glutamyl-L-arginyl-L-alanyl-L-arginyl-L-leucyl-L-leucyl-L-alanyl-L-alanyl-L-leucyl-L-alpha-glutamyl-L-arginyl-L-arginyl-L-histidyl-L-tryptophyl-L-leucyl-L-asparagyl-L-seryl-L-tyrosyl-L-methionyl-L-histidyl-L-lysyl-L-leucyl-L-leucyl-L-valyl-L-leucyl-L-alpha-aspartyl-L-alanyl-L-proline. Grades: ≥95% by HPLC. CAS No. 277302-47-3. Molecular formula: C202H325N61O54S. Mole weight: 4504.17.
TLQP 21
TLQP 21 is a VGF-derived peptide. TLQP 21 has been shown to protect cerebellar granule cells (CGCs) from serum and potassium deprivation-induced apoptosis. TLQP 21 has the potential for the prevention of early phase diet-induced diabetes. Synonyms: TLQP 21; TLQP21; TLQP-21. Grades: ≥95%. CAS No. 869988-94-3. Molecular formula: C107H170N40O26. Mole weight: 2432.7.
TMP-CP
TMP-CP is a non-hydrolytic analogue of thymidine-5'-diphosphate and an inhibitor of thymidine kinase. It is also used as a starting structure in the synthesis of α/β hydrolysis-resistant tri- and polyphosphates. Synonyms: Thymidine- 5'- O- (α, β- methylene)diphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 55065-40-2. Molecular formula: C11H18N2O10P2 (free acid). Mole weight: 400.2 (free acid).
Topoisomerase II-alpha-b (828-836)
Topoisomerase II-alpha-b (828-836) is a peptide derived from Topoisomerase II-alpha-b. Topoisomerase II-alpha is an enzyme that controls and alters the topologic states of DNA during transcription. Human topoisomerase II enzymes are targets for a number of widely used anticancer agents.
Tos-Gly-Pro-Arg-ANBA-IPA
A chromogenic peptide substrate. CAS No. 99700-50-2. Molecular formula: C30H41N9O8S. Mole weight: 687.77.
Tos-Gly-Pro-Arg-ANBA-IPA acetate
Tos-Gly-Pro-Arg-ANBA-IPA acetate is the acetate of Tos-Gly-Pro-Arg-ANBA-IPA which is a chromogenic peptide substrate. Synonyms: tos-GPR-ANBA-IPA acetate. CAS No. 2070009-46-8. Molecular formula: C32H45N9O10S. Mole weight: 747.82.
Tosyllysine chloromethyl ketone hydrochloride
Tosyllysine chloromethylketone (TLCK) is an inhibitor of serine proteinases. It inhibits mitochondrial damage and cell death. Uses: Serine proteinase inhibitors. Synonyms: 1-Chloro-3-Toxylamide-7-Amino-L-2-Heptanone hydrochloride; TLCK hydrochloride; TLCK HCl; (S)-N-(7-Amino-1-chloro-2-oxoheptan-3-yl)-4-methylbenzenesulfonamide hydrochloride; (3S)-1-Chloro-3-tosylamido-7-amino-2-heptanone hydrochloride. Grades: ≥98%. CAS No. 4272-74-6. Molecular formula: C14H21ClN2O3S·HCl. Mole weight: 369.3.
Tosyl phenylalanyl chloromethyl ketone
Tosyl phenylalanyl chloromethyl ketone (TPCK) is an irreversible inhibitor of chymotrypsin-like proteases. It also inhibits some cysteine proteases such as caspase, papain, bromelain or ficin. Uses: Alkylating agents. Synonyms: Nα-Tosyl-L-Phenylalanine Chloromethyl Ketone; TPCK; Tos-Phe-CH2Cl. Grades: ≥98%. CAS No. 402-71-1. Molecular formula: C17H18ClNO3S. Mole weight: 351.8.
Tousled-like kinase 1
The Tousled-like kinases (Tlk) are serine/threonine kinases that are evolutionarily conserved in both animals and plants. Synonyms: TLK1.
TP508
TP508, also known as Chrysalin (OrthoLogic, Tempe, Arizona), is a 23 amino acid synthetic peptide representing residues 508-530 of human prothrombin. TP508 is a regenerative peptide drug representing a natural part of human thrombin that is released upon tissue injury to initiate a healing cascade. TP508 has demonstrated safety and potential efficacy in non-clinical and in human clinical tissue repair trials. Synonyms: TP508; TP 508; TP-508. Molecular formula: C97H146N28O36S. Mole weight: 2312.44.
TPA: ovochymase precursor (314-332)
TPI HLA-DR1
A peptide used in the research on the treatment of melanoma.