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(S)-(+)-Niguldipine hydrochloride
(S)-(+)-Niguldipine hydrochloride, the more active enantiomer of Niguldipine hydrochloride, acts as a potent, selective α1A-adrenoceptor antagonist (Ki = 0.16 nM), and also is a L-type Ca2+ channel blocker. Uses: Antihypertensive agents. Synonyms: 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-[3-(4,4-diphenyl-1-piperidinyl)propyl] 5-methyl ester, hydrochloride (1:1), (4S)-; 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-(4,4-diphenyl-1-piperidinyl)propyl methyl ester, monohydrochloride, (4S)-; 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-(4,4-diphenyl-1-piperidinyl)propyl methyl ester, monohydrochloride, (S)-; (+)-Niguldipine hydrochloride; (S)-Niguldipine hydrochloride; B 8509-034; BY 934; Niguldipine hydrochloride. Grade: ≥95%. CAS No. 113145-69-0. Molecular formula: C36H39N3O6.HCl. Mole weight: 646.18.
(S)-(+)-Nirvanol
(S)-(+)-Nirvanol is a Mephentoin metabolite with anticonvulsant and hypnotic properties. Uses: An anticonvulsant, hypnotic. a metabolite of mephentoin. Synonyms: (+)-5-Ethyl-5-phenylhydantoin; S-Nirvanol. CAS No. 65567-34-2. Molecular formula: C11H12N2O2. Mole weight: 204.23.
(S)-nitro-Blebbistatin
(S)-nitro-Blebbistatin is a more stable form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. Synonyms: S-(-)-7-Desmethyl-8-nitro Blebbistatin; (3aS)-3a-hydroxy-7-nitro-1-phenyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-one. Grade: ≥98%. CAS No. 856925-75-2. Molecular formula: C17H13N3O4. Mole weight: 323.3.
(S)-N,N-dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-3-yl)propan-1-amine is an impurity of Duloxetine, an antidepressant medication used to treat major depressive disorder. Synonyms: Duloxetine IMpurity 19. CAS No. 1384080-33-4. Molecular formula: C8H13NOS. Mole weight: 171.26.
An impurity of Dapoxetine. Dapoxetine is a selective serotonin reuptake inhibitor (SSRI) specifically designed to treat premature ejaculation (PE) in adult men. Synonyms: Benzenemethanamine, N,N-dimethyl-α-[2-(2-naphthalenyloxy)ethyl]-, hydrochloride (1:1), (αS)-; Dapoxetine hydrochloride Impurity-B; (S)-N,N-Dimethyl-1-phenyl-3-(1-naphthalenyloxy)propanamine hydrochloride; S-(+)-N,N-Dimethyl-a-[2-(naphthalenyloxy)ethyl] benzenemethanamine hydrochloride; Dapoxetine Impurity B hydrochloride. Grade: ≥95%. CAS No. 1135305-10-0. Molecular formula: C21H23NO.HCl. Mole weight: 341.88.
(S)-N-Nitroso Anabasine
(S)-N-Nitroso Anabasine is the S-enantiomer metabolite of tobacco, a specific N-nitrosamine with carcinogenic activity. Synonyms: (S)-3-(1-nitroso-2-piperidinyl)pyridine. Grade: 95%. CAS No. 1133-64-8. Molecular formula: C10H13N3O. Mole weight: 191.23.
(S)-N-Nitroso Anatabine
(S)-N-Nitroso Anatabine is the S-enantiomer metabolite of tobacco, a specific N-nitrosamine with carcinogenic activity. Synonyms: 2,3'-Bipyridine, 1,2,3,6-tetrahydro-1-nitroso-, (2S)-; N'-Nitrosoanatabine. Grade: 95%. CAS No. 71267-22-6. Molecular formula: C10H11 N3 O. Mole weight: 189.21.
(S)-Noradrenaline
(S)-Noradrenaline is the S-enantiomer of Noradrenaline, which is widely used as an injectable drug for the treatment of critically low blood pressure. Synonyms: (S)-4-(2-Amino-1-hydroxyethyl)pyrocatechol; (S)-Norepinephrine; (+)-Norepinephrine; D-Arterenol; D-Norepinephrine; 1,2-Benzenediol, 4-[(1S)-2-amino-1-hydroxyethyl]-; D-Noradrenaline; (+)-Noradrenaline; S-(+)-Norepinephrine; (+)-4-[(S)-2-Amino-1-hydroxyethyl]-1,2-benzenediol. Grade: 95%. CAS No. 149-95-1. Molecular formula: C8H11NO3. Mole weight: 169.18.
(S)-O-[2-(Acetylamino)-3-O-benzoyl-2-deoxy-4,6-O-benzylidene-α-D-galactopyranosyl]-N-9-Fmoc-L-serine Phenacyl Ester is a biochemical compound applied extensively in biomedical research as a key reagent in synthetic organic chemistry. It is vital in research to synthesize drugs for the treatment of various diseases such as cancer and infectious diseases. Uses: Intermediate in the preparation of stn epitope. Synonyms: (S)-O-[2-(Acetylamino)-3-O-benzoyl-2-deoxy-4,6-O-(phenylmethylene)-α-D-galactopyranosyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-serine 2-Oxo-2-phenylethyl Ester. CAS No. 171973-67-4. Molecular formula: C48H44N2O12. Mole weight: 840.87.
(S)-O-Demethylmetoprolol
(S)-O-Demethylmetoprolol is an impurity of Betaxolol, which is a selective beta1 adrenergic receptor blocker for the treatment of hypertension and glaucoma. Synonyms: O-Demethylmetoprolol, (-)-; (S)-(-)-O-Demethylmetoprolol. CAS No. 131564-69-7. Molecular formula: C14H23NO3. Mole weight: 253.342.
(S)-(-)-O-Desmethyl Carvedilol
(S)-(-)-O-Desmethyl Carvedilol is an optically active metabolite of Carvedilol, which is a medication used to treat high blood pressure, congestive heart failure (CHF), and left ventricular dysfunction in otherwise stable people. Synonyms: (S)-2-[2-[[3-(9H-Carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]phenol; (S)-(-)-O-Desmethylcarvedilol; Phenol, 2-[2-[[3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]-, (S)-. Grade: 95%. CAS No. 123372-13-4. Molecular formula: C23H24N2O4. Mole weight: 392.45.
(S)-O-Desmethyl Rabeprazole Impurity
S enantiomer of O-Desmethyl Rabeprazole.O-Desmethyl Rabeprazole is an impurity of Rabeprazole. Rabeprazole is proton pump inhibitor as an antiulcer drug. Grade: > 95%. CAS No. 179952-05-7. Molecular formula: C17H19N3O3S. Mole weight: 345.42.
(S)-(-)-Ofloxacin-d3(N-methyl-d3)
One of the isotopic labelled form of (S)-(-)-Ofloxacin, which could be used as an an antibiotic. Synonyms: Levofloxacin; (3S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-piperidino[1,2,3-d,e]-1,4-benzoxazine-6-carboxylic Acid. Grade: 95% by HPLC; 98% atom D. Molecular formula: C18H17D3FN3O4. Mole weight: 364.39.
(S)-Oxiracetam
An isomer of Oxiracetam which is a substance that belongs to the racetam family. Synonyms: (4S)-4-Hydroxy-2-oxo-1-pyrrolidineacetamide. Grade: > 95%. CAS No. 88929-35-5. Molecular formula: C6H10N2O3. Mole weight: 158.16.
(S)-Oxybutynin
(S)-Oxybutynin is an anticholinergic drug that inhibits muscarinic receptors in bladder smooth muscle and thus prevents the acetylcholine binding. Synonyms: Esoxybutynin; S-oxybutynin; 4-(diethylamino)but-2-ynyl (2S)-2-cyclohexyl-2-hydroxy-2-phenylacetate. CAS No. 119618-22-3. Molecular formula: C22H31NO3. Mole weight: 357.494.
(S)-Oxybutynin HCl
(S)-Oxybutynin HCl is a salt form of (S)-Oxybutynin that inhibits muscarinic receptors in bladder smooth muscle and thus prevents the acetylcholine binding. Synonyms: (S)-Oxybutynin hydrochloride; Esoxybutynin Chloride; (s)-oxybutynin chloride. CAS No. 230949-16-3. Molecular formula: C22H32ClNO3. Mole weight: 393.952.
(S)-p38 MAPK Inhibitor III
(S)-p38 MAPK inhibitor III is a methylsulfanylimidazole that inhibits p38 MAP kinase (IC50 = 0.90 μM in vitro). It is cell-permeable, potently blocking the release of TNF-α and IL-1β from human peripheral blood mononuclear cells (IC50s = 0.37 and 0.044 μM, respectively). Synonyms: (S)-p38 MAP Kinase Inhibitor III; 4-[5-(4-fluorophenyl)-2-(methylthio)-1H-imidazol-4-yl]-N-[(1S)-1-phenylethyl]-2-pyridinamin; (S)-p38 Mitogen-activated Protein Kinase Inhibitor III. Grade: ≥98%. CAS No. 581098-48-8. Molecular formula: C23H21FN4S. Mole weight: 404.5.
(S)-(-)-Pantoprazole
An impurity of Pantoprazole which is a prescription drug used as a short-term treatment for gastroesophageal reflux disease (GERD). Synonyms: (-)-Pantoprazole; Zosecta; L-Pantoprazole; 142678-35-1; S-(-)-Pantoprazole; S-Pantoprazole; SX78SGO2TV; Pantoprazole, S-; UNII-SX78SGO2TV; 1H-Benzimidazole, 6-(difluoromethoxy)-2-((S)-((3,4-dimethoxy-2-pyridinyl)methyl)sulfinyl)-; 6-(difluoromethoxy)-2-[(S)-(3,4-dimethoxypyridin-2-yl)methylsulfinyl]-1H-benzimidazole; (S)-(-)-Pantoprazole; PANTOPRAZOLE, (S)-; SCHEMBL29466; CHEMBL3526697; S-PANTOPRAZOLE [WHO-DD]; IQPSEEYGBUAQFF-SANMLTNESA-N; DTXSID201015709; PD119113; Q27289440. Grade: > 95%. CAS No. 142678-35-1. Molecular formula: C16H15F2N3O4S. Mole weight: 383.38.
(S)-Pantoprazole-d6
A deuterated labelled of Pantoprazole which is used to treat erosive esophagitis (damage to the esophagus from stomach acid), and other conditions involving excess stomach acid such as Zollinger-Ellison syndrome. Grade: > 95%. Molecular formula: C16H9F2N3O4SD6. Mole weight: 389.41.
(S)-PFI 2 hydrochloride
(S)-PFI 2 hydrochloride, a negative control of (R)-PFI 2 hydrochloride which a potent, cell-permeable inhibitor of SET7/9 (IC50 = 2 nM), shows 500-fold lower activity in a SETD7 enzymatic assay (IC50 = 1 μM) compared to the active enantiomer. Synonyms: (S)-PFI 2 hydrochloride; (S)-PFI2 hydrochloride; (S)-PFI-2 hydrochloride; (1S)-1-[[3-(Trifluoromethyl)phenyl]methyl]-2-oxo-2-(1-pyrrolidinyl)ethyl]1,2,3,4-tetrahydro-6-isoquinolinesulfonamide hydrochloride. Grade: ≥97% by HPLC. CAS No. 1627607-88-8. Molecular formula: C23H25F4N3O3S.HCl. Mole weight: 535.98.
(S)-Phenprocoumon
An isomer of Phenprocoumon which is used as an oral anti-coagulant. Synonyms: (S)-Phenprocoumon; 3770-63-6; Phenprocoumon, (S)-; UNII-3DM685514V; 2H-1-Benzopyran-2-one, 4-hydroxy-3-(1-phenylpropyl)-, (S)-; 3DM685514V; 4-hydroxy-3-[(1S)-1-phenylpropyl]chromen-2-one; (-)-PHENPROCOUMON; S-(-)-PHENPROCOUMON; SCHEMBL414250; CHEMBL3589649; SCHEMBL24500477; Coumarin, 3-(.alpha.-ethylbenzyl)-4-hydroxy-, S-(-)-; DTXSID20191141; PD132288; EN300-25607520; Q27257083; 4-hydroxy-3-[(1S)-1-phenylpropyl]-2H-chromen-2-one; 2H-1-BENZOPYRAN-2-ONE, 4-HYDROXY-3-((1S)-1-PHENYLPROPYL)-. Grade: > 95%. CAS No. 3770-63-6. Molecular formula: C18H16O3. Mole weight: 280.33.
(S)-Phenylephrine-d3 Hydrochloride
An impurity of Phenylephrine which is a decongestant that shrinks blood vessels in the nasal passages. Synonyms: (αS)-3-Hydroxy-α-[(methylamino)methyl]benzenemethanol-d3 Hydrochloride (1:1); (+)-m-Hydroxy-α-[(methylamino)methyl]-benzyl Alcohol-d3; (+)-Phenylephrine-d3 Hydrochloride. Grade: > 95%. Molecular formula: C9H10NO2D3·HCl. Mole weight: 206.69.
(S)-Phenylephrine HCl
An impurity of Phenylephrine which is an oral selective α1-adrenergic receptor agonist. Synonyms: 939-38-8; (+)-Phenylephrine hydrochloride; (S)-Phenylephrine Hydrochloride; UNII-95T627AGR395T627AGR3. Grade: > 95%. CAS No. 939-38-8. Molecular formula: C9H13NO2.HCl. Mole weight: 203.67.
(S)-Phenylglycine-d5
(S)-Phenylglycine-d5 is a labelled (S)-Phenylglycine. (R)-Phenylglycine is a derivative of glycine. Synonyms: L-Phenylglycine-d5; (S)-2-Amino-2-phenylacetic acid-d5; L-(+)-alpha-Phenylglycine-d5; L-2-Phenylglycine-d5. Grade: 95% by HPLC; 98% atom D. Molecular formula: C8H4D5NO2. Mole weight: 156.20.
(S)-PI3Kα-IN-4
(S)-PI3Kα-IN-4 is a potent, selective inhibitor of PI3Kα with an IC50 of 2.3 nM. It can be used for the research of cancer. Grade: 99%. CAS No. 2322293-84-3. Molecular formula: C25H23ClFN5O5S. Mole weight: 560.00.
(S)-(-)-Pindolol
(S)-(-)-Pindolol, the more active enantiomer of pindolol, is 5-HT1A/1B receptor antagonist, with roughly equal affinity for each subtype. Synonyms: (S)-1-(1H-indol-4-yloxy)-3-[(1-methylethyl)amino]-2-propanol; AGI-001; MT-102; AGI001; MT102; AGI 001; MT 102; Espindolol; (S)-(-)-Pindolol. Grade: ≥99% by HPLC. CAS No. 26328-11-0. Molecular formula: C14H20N2O2. Mole weight: 248.32.
(S)-Pomalidomide
The S isometric form of Pomalidomide which inhibits lipopolysaccharide (LPS) stimulated TNF-alpha release in human PBMC and in human whole blood with IC50 values of 13 nM and 25 nM, respectively. Synonyms: (S)-pomalidomide; 202271-89-4; S-Pomalidomide; Pomalidomide, (S)-; Pomalidomide, (-)-; 2EE4M42K6G; (S)-CC-4047; 4-AMINO-2-[(3S)-2,6-DIOXOPIPERIDIN-3-YL]ISOINDOLE-1,3-DIONE; (S)-4-Amino-2-(2,6-dioxo-3-piperidinyl)isoindole-1,3-dione; (s)-4-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione; 1H-Isoindole-1,3(2H)-dione, 4-amino-2-((3S)-2,6-dioxo-3-piperidinyl)-; 1H-Isoindole-1,3(2H)-dione, 4-amino-2-(2,6-dioxo-3-piperidinyl)-, (S)-; 1H-Isoindole-1,3(2H)-dione, 4-amino-2-((3S)-2,6-dioxo-3-piperidinyl)-, (-)-; Y70; 4ci3; UNII-2EE4M42K6G; SCHEMBL563317; CHEMBL2093113; PD132344; Q27254625; 4-amino-2-[(3S)-2,6-dioxopiperidin-3-yl]-1H-isoindole-1,3(2H)-dione. Grade: > 95%. CAS No. 202271-89-4. Molecular formula: C13H11N3O4. Mole weight: 273.25.
(S)-Posenacaftor sodium
(S)-Posenacaftor sodium is the S-enantiomer of Posenacaftor. Posenacaftor is a cystic fibrosis transmembrane regulator (CFTR) protein modulator that corrects the folding and trafficking of CFTR protein. It is used in cystic fibrosis (CF) studies. Synonyms: (S)-PTI-801 sodium; Sodium 8-methyl-2-(3-methyl-1-benzofuran-2-yl)-5-[(1S)-1-(tetrahydro-2H-pyran-4-yl)ethoxy]-4-quinolinecarboxylate; 4-Quinolinecarboxylic acid, 8-methyl-2-(3-methyl-2-benzofuranyl)-5-[(1S)-1-(tetrahydro-2H-pyran-4-yl)ethoxy]-, sodium salt (1:1). CAS No. 2095064-09-6. Molecular formula: C27H26NNaO5. Mole weight: 467.49.
(S)-PPHT hydrochloride
(S)-PPHT hydrochloride is a potent and selective D2 agonist. Uses: Dopamine agonists. Synonyms: (6S)-6-[2-phenylethyl(propyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride. Grade: 98%. CAS No. 159795-62-7. Molecular formula: C21H27NO.HCl. Mole weight: 345.91.
(S)-Pramipexole-d7 2HCl (N-propyl-d7)
One of the isotopic labelled form of (S)-Pramipexole HCl, which is a dopamine-D2 receptor agonist and could be used as an antiparkinsonian agent. Synonyms: (S)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole 2HCl. Grade: 95% by HPLC; 98% atom D. Molecular formula: C10H10D7N3S?2HCl. Mole weight: 291.29.
(S)-Prasugrel Thiolactone
(S)-Prasugrel Thiolactone is an impurity of Prasugrel, which is a platelet inhibitor used to prevent formation of blood clots. Synonyms: Thieno[3,2-c]pyridin-2(4H)-one, 5-[(1S)-2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-5,6,7,7a-tetrahydro-; 5-[(1S)-2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one; (S)-2-Oxo-Prasugrel; 5-((S)-2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one. CAS No. 2747961-46-0. Molecular formula: C18H18FNO2S. Mole weight: 331.41.
(S)-Praziquantel
S configuration of Praziquantel.Praziquantel can be used for the treatment of a number of types of parasitic worm infections. Specifically it is used for schistosomiasis, clonorchiasis, opisthorchiasis, tapeworm infections, cysticercosis, hydatid disease, and other fluke infections. Grade: > 95%. CAS No. 57452-97-8. Molecular formula: C19H24N2O2. Mole weight: 312.42.
(S)-Primaquine carbamoyl-β-D-glucuronide
(S)-Primaquine carbamoyl-β-D-glucuronide is a metabolite of Primaquine. Primaquine is an antimalarial drug primarily used to treat and prevent malaria caused by Plasmodium parasites, particularly for its effectiveness against the liver stages of Plasmodium vivax and Plasmodium ovale, which helps prevent relapses. Synonyms: (4S)-N4-(6-Methoxy-8-quinolinyl)-1,4-pentanediamine carbamoyl-β-D-glucuronide; (+)-Primaquine carbamoyl-β-D-glucuronide; (S)-(+)-Primaquine carbamoyl-β-D-glucuronide; d-Primaquine carbamoyl-β-D-glucuronide; (2S,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-((((S)-4-((6-methoxyquinolin-8-yl)amino)pentyl)carbamoyl)oxy)tetrahydro-2H-pyran-2-carboxylic acid. Grade: ≥98%. CAS No. 2189731-58-4. Molecular formula: C22H29N3O9. Mole weight: 479.48.
(S)-Propranolol β-D-Glucuronide Sodium Salt
A metabolite of Propranolol. Propranolol is Beta 1 adrenergic receptor antagonist. It can be used for the treatment of high blood pressure, a number of types of irregular heart rate, thyrotoxicosis, capillary hemangiomas, performance anxiety, and essential tremors. Synonyms: (S)-1-[[(1-Methylethyl)amino]methyl]-2-(1-naphthalenyloxy)ethyl b-D-glucopyranosiduronic acid monosodium salt; (-)-Propranolol glucuronide sodium; (S)-Propranolol glucuronide sodium. Grade: > 95%. CAS No. 87144-73-8. Molecular formula: C22H28NNaO8. Mole weight: 457.45.
(S)-Propranolol glucuronide
(S)-Propranolol glucuronide is the metabolite formed in vivo upon the administration of Propranololan efficacious beta-blocker that features in the treatment of hypertension, angina, and arrhythmias. This glucuronide is inactivated and subsequently renally cleared via the urinary tract. The relatively low molecular weight of (S)-Propranolol glucuronide, which permits facile urine excretion, belies its significance as a marker for assessing the pharmacokinetics of Propranolol. Synonyms: (S)-Propranolol-O-beta-D-glucuronide; (1S)-1-[[(1-Methylethyl)amino]methyl]-2-(1-naphthalenyloxy)ethyl β-D-glucopyranosiduronic acid; β-D-Glucopyranosiduronic acid, 1-[[(1-methylethyl)amino]methyl]-2-(1-naphthalenyloxy)ethyl, (S)-; (-)-Propranolol glucuronide. CAS No. 58657-78-6. Molecular formula: C22H29NO8. Mole weight: 435.47.
(S)-Pro-xylane
(S)-Pro-xylane can be used to improve skin elasticity and alleviate skin aging, medical and beauty chemicals, cosmetic active raw materials. Synonyms: 1,5-Anhydro-6,8-dideoxy-L-glycero-L-gluco-octitol; (2S,3R,4S,5R)-2-((S)-2-Hydroxypropyl)tetrahydro-2H-pyran-3,4,5-triol; (S)-Hydroxypropyl tetrahydropyrantriol. Grade: >95%. CAS No. 868156-46-1. Molecular formula: C8H16O5. Mole weight: 192.21.
(S)-Prunasin
It is useful to the synthesis of cyanogen glycoside, a component contains in antiperspirants, deodorants, body soaps, shampoos, hair rinses, and hair, which inhibits volatile steroid formation by resident bacteria. Uses: Used in the synthesis of cyanogen glycoside. a component contains in antiperspirants, deodorants, body soaps, shampoos, hair rinses, and hair. Synonyms: (αS)-α-(β-D-Glucopyranosyloxy)benzeneacetonitrile; L-Prunasin; Sambunigrin; (2S)-Sambunigrin. Grade: 95%. CAS No. 99-19-4. Molecular formula: C14H17NO6. Mole weight: 295.29.
(S)-Prunasin Tetraacetate
(S)-Prunasin Tetraacetate, a formidable biomedicine, has emerged as a frontrunner in cancer therapy. Leveraging its unparalleled chemical composition, it diligently antagonizes tumor expansion and enforces cell death via apoptosis induction. Notably, by selectively targeting malignant cells and disrupting their intricate growth cascades, this exceptional marvel confronts cancer head-on. Furthermore, it seamlessly synergizes with concurrent anticancer interventions, augmenting their potency while mitigating unwarranted adversities. Synonyms: (S)-α-[(2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl)oxy]benzeneacetonitrile; Benzeneacetonitrile, α-[(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)oxy]-, (S)-; Sambunigrin tetraacetate. CAS No. 60981-44-4. Molecular formula: C22H25NO10. Mole weight: 463.43.
(S)-Quarfloxin
(S)-Quarfloxin is a fluoroquinolone derivative that targets the inhibition of RNA pol I activity and has antitumor activity. Synonyms: 3H-Benzo[b]pyrido[3,2,1-kl]phenoxazine-2-carboxamide, 5-fluoro-N-[2-[(2S)-1-methyl-2-pyrrolidinyl]ethyl]-3-oxo-6-[(3S)-3-(2-pyrazinyl)-1-pyrrolidinyl]-; 3H-Benzo[b]pyrido[3,2,1-kl]phenoxazine-2-carboxamide, 5-fluoro-N-[2-[(2S)-1-methyl-2-pyrrolidinyl]ethyl]-3-oxo-6-[(3S)-3-pyrazinyl-1-pyrrolidinyl]-; 5-Fluoro-N-[2-[(2S)-1-methyl-2-pyrrolidinyl]ethyl]-3-oxo-6-[(3S)-3-(2-pyrazinyl)-1-pyrrolidinyl]-3H-benzo[b]pyrido[3,2,1-kl]phenoxazine-2-carboxamide; 5-fluoro-N-(2-((S)-1-methylpyrrolidin-2-yl)ethyl)-3-oxo-6-((S)-3-(pyrazin-2-yl)pyrrolidin-1-yl)-3H-benzo[b]pyrido[3,2,1-kl]phenoxazine-2-carboxamide; Quarfloxin, (S)-; Itarnafloxin, (S)-. Grade: ≥95%. CAS No. 783364-52-3. Molecular formula: C35H33FN6O3. Mole weight: 604.67.
(S)-Quinuclidin-3-amine
(S)-Quinuclidin-3-amine is an intermediate in the synthesis of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Synonyms: (3S)-Aminoquinuclidine; (S)-1-Azabicyclo[2.2.2]oct-3-ylamine; (S)-3-Amino-1-azabicyclo[2.2.2]octane; (S)-3-Aminoquinuclidine; (S)-(-)-3-Aminoquinuclidine; (S)-1-Azabicyclo[2.2.2]octan-3-amine. Grade: 95%. CAS No. 120570-05-0. Molecular formula: C7H14N2. Mole weight: 126.20.
(S)-Rabeprazole Sodium Salt
S enantiomer of Rabeprazole Sodium Salt. Rabeprazole is proton pump inhibitor as an antiulcer drug. Uses: Anti-ulcer agents. Synonyms: 2-[(S)-[[4-(3-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole Sodium Salt; S-(-)-Rabeprazole Sodium Salt. Grade: > 95%. CAS No. 171440-19-0. Molecular formula: C18H23N3O3S. Na. Mole weight: 384.46.
(S)-Ramosetron
S enantiomer of Ramosetron.Ramosetron is a serotonin 5-HT3 receptor antagonist for the treatment of nausea and vomiting. Synonyms: (S)-Ramosetron; 132036-90-9; (1-methylindol-3-yl)-[(5S)-4,5,6,7-tetrahydro-3H-benzimidazol-5-yl]methanone; SCHEMBL9048395; DTXSID601130426; 5-[(1-Methylindole-3-yl )carbonyl]-4,5,6,7-Tetrahydro-1H-bezimidazole; (S)-(1-methyl-1H-indol-3-yl)(4,5,6,7-tetrahydro-1H-benzo[d]imidazol-6-yl)methanone; Methanone, (1-methyl-1H-indol-3-yl)(4,5,6,7-tetrahydro-1H-benzimidazol-5-yl)-, (S)-. Grade: > 95%. CAS No. 132036-90-9. Molecular formula: C17H17N3O. Mole weight: 279.34.
(S)-Ranolazine
(S)-Ranolazine is the S-isomer of Ranolazine, which is a medication used to treat heart-related chest pain. Synonyms: 1-Piperazineacetamide, N-(2,6-dimethylphenyl)-4-[(2S)-2-hydroxy-3-(2-methoxyphenoxy)propyl]-; N-(2,6-Dimethylphenyl)-2-{4-[(2S)-2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazinyl}acetamide; (-)-Ranolazine. Grade: ≥95%. CAS No. 114246-81-0. Molecular formula: C24H33N3O4. Mole weight: 427.54.
(S,R)-Bortezomib Hydroxyisopentyl Amide Analog
(S,R)-Bortezomib Hydroxyisopentyl Amide Analog is an isomer of Bortezomib. It has been demonstrated to inhibit serine proteases shown to lower cellular Aβ concentrations, associated with Alzheimer's or hypertension. Synonyms: N-((S)-1-(((R)-1-Hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide; (R)-Hydroxy Des(boric Acid) Bortezomib; Bortezomib Hydroxy Impurity (1R,2S)-Isomer. Grade: 98% by HPLC. CAS No. 289472-78-2. Molecular formula: C19H24N4O3. Mole weight: 356.43.
(S,R)-Palonosetron Acid
(S,R)-Palonosetron Acid is an impurity of Palonosetron, which is a potent, single stereoisomeric 5-HT3 receptor antagonist developed to prevent chemotherapy-induced nausea and vomiting. Synonyms: (S)-8-(((R)-quinuclidin-3-ylamino)methyl)-5,6,7,8-tetrahydronaphthalene-1-carboxylic acid. Molecular formula: C19H26N2O2. Mole weight: 314.42.
(S,R)-Palonosetron HCl
An impurity of Palonosetron which is 5-HT3 receptor blocker and works by blocking the action of serotonin in certain parts of the brain and nervous system so helps reduce or prevent nausea and vomiting. Uses: Antiemetics. Synonyms: Palonosetron (S,R)-Isomer (HCl Salt); (3aS)-2-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-1H-benz[de]isoquinolin-1-one HCl. Grade: > 95%. CAS No. 135729-76-9. Molecular formula: C19H24N2O.HCl. Mole weight: 332.86.
(S, R)-Reboxetine
A stereoisomer of Reboxetine.Reboxetine is a norepinephrine reuptake inhibitor. It can be used for the treatment of unipolar depression, although it has also been used off-label for panic disorder and ADHD. Grade: > 95%. CAS No. 868686-70-8. Molecular formula: C19H23NO3. Mole weight: 313.4.
(S,R,R,R)-Orlistat
An impurity of Orlistat. Orlistat is a pancreatic lipase inhibitor that aids in weight loss by blocking the absorption of dietary fats in the gastrointestinal tract. Synonyms: N-Formyl-L-leucine (1R)-1-[[(2R,3R)-3-Hexyl-4-oxo-2-oxetanyl]methyl]dodecyl Ester; [2R-[2α(R*),3β]]-N-Formyl-L-leucine 1-[(3-Ηexyl-4-oxo-2-oxetanyl)methyl]dodecyl Ester. Grade: > 95%. CAS No. 111466-61-6. Molecular formula: C29H53NO5. Mole weight: 495.75.
(S,R,S,S) Orlistat
An impurity of Orlistat. Orlistat is a pancreatic lipase inhibitor that aids in weight loss by blocking the absorption of dietary fats in the gastrointestinal tract. Synonyms: [2S-[2α(S*),3β]]-N-Formyl-L-leucine 1-[(3-Hexyl-4-oxo-2-oxetanyl)methyl]dodecyl Ester. Grade: > 95%. CAS No. 111466-63-8. Molecular formula: C29H53NO5. Mole weight: 495.75.
(S)-Ruxolitinib
Ruxolitinib S enantiomer, the chirality of INCB018424, is a potent and selective small-molecule Janus kinase 1 (JAK1) and JAK2 inhibitor to enter the clinic. It was initially developed to target the constitutive activation of the JAK-STAT pathway. It maintains its anti-JAK activity by competitive inhibition of the ATP-binding catalytic site of the kinase domain. It is well absorbed at above 95%. Synonyms: Ruxolitinib (S enantiomer); (S)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile. Grade: 95%. CAS No. 941685-37-6. Molecular formula: C17H18N6. Mole weight: 306.37.
(S)-Ruxolitinib Phosphate
(S)-Ruxolitinib Phosphate is an impurity of Ruxolitinib phosphate. Ruxolitinib phosphate is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM, >130-fold selectivity for JAK1/2 versus JAK3. Synonyms: Ruxolitinib (S)-Isomer Phosphate; (S)-3-(4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile Phosphate. Grade: 95%. CAS No. 2703484-89-1. Molecular formula: C17H21N6O4P. Mole weight: 404.37.
(S,S)-(-)-1,4-Dimethoxy-2,3-butanediol
(S,S)-(-)-1,4-Dimethoxy-2,3-butanediol, an intriguing chemical compound renowned for its multifaceted biomedical potential, assumes a pivotal role in synthesizing an extensive range of formidable pharmaceutical intermediates. Synonyms: (-)-1,4-Di-O-methyl-L-threitol. CAS No. 50622-10-1. Molecular formula: C6H14O4. Mole weight: 150.17.
(S,S)-3-Hydroxy Lovastatin
(S,S)-3-Hydroxy Lovastatin is a metabolite of Lovastatin. Synonyms: [1S-[1α(2R*,3R*),3α,7β,8β(2S*,4S*),8aβ]]-3-Hydroxy-2-methylbutanoic Acid 1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran- 2-yl)ethyl]-1-naphthalenyl Ester. Grade: > 95%. CAS No. 127910-58-1. Molecular formula: C24H36O6. Mole weight: 420.54.
(S,S)-Adenosyl-L-Methionine
(S,S)-Adenosyl-L-Methionine is a paramount compound harnessed within the research of the pernicious afflictions of depression, osteoarthritis and liver diseases. Functioning as a proficient methyl donor, it diligently participates in an array of metabolic pathways, thereby facilitating the synthesis of neurotransmitters and proteins. Grade: > 95%. Molecular formula: C15H22N6O5S. Mole weight: 398.44.
(S)-Salbutamol hydrochloride
(S)-Salbutamol is an isomer of Salbutamol. Salbutamol is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart. Synonyms: 1,3-Benzenedimethanol, α1-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-, hydrochloride (1:1), (α1S)-; 1,3-Benzenedimethanol, α-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-, hydrochloride, (αS)-; 1,3-Benzenedimethanol, α1-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-, hydrochloride, (S)-; (+)-Salbutamol hydrochloride; (S)-Albuterol hydrochloride; (+)-Albuterol hydrochloride; (S)-(+)-Salbutamol hydrochloride. Grade: >95%. CAS No. 50293-91-9. Molecular formula: C13H21NO3.HCl. Mole weight: 275.78.
(S)-Salsolidine
(S)-Salsolidine is a weak monoamine oxidase (MAO) inhibitor with a Ki of 63 μM. Synonyms: Salsolidine; (S)-6,7-Dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline. CAS No. 493-48-1. Molecular formula: C12H17NO2. Mole weight: 207.27.
(S,S)-Asenapine Maleate
A metabolite of Asenapine. Uses: Antipsychotic agents. Synonyms: S,S-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7] oxepino[4,5-c]pyrrole Maleate. Grade: > 95%. CAS No. 135883-08-8. Molecular formula: C17H16ClNO. C4H4O4. Mole weight: 285.78 116.07.
(S,S)-Formoterol
(S,S)-Formoterol is a powerful and meticulously targeted β2-adrenergic receptor agonist, successfully harnessed in the research of asthma and chronic obstructive pulmonary disease (COPD). Uses: Antiasthmatic. Synonyms: Formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, [S-(R*,R*)]-; N-[2-Hydroxy-5-[(S)-1-hydroxy-2-[[(S)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]formamide. Grade: > 95%. CAS No. 67346-48-9. Molecular formula: C19H24N2O4. Mole weight: 344.41.
(S)-SHA 68
(S)-SHA 68 is the S enantiomer of SHA 68, which is a selective neuropeptide S receptor (NPSR) antagonist. Grade: >98%. CAS No. 847555-75-3. Molecular formula: C26H24FN3O3. Mole weight: 445.49.
(S)-Silodosin (Silodosin Impurity 4)
A stereoisomer of silodosin. Silodosin is an α1-adrenoceptor antagonist for the treatment of benign prostatic hypertrophy. Synonyms: (S)-1-(3-Hydroxypropyl)-5-(2-((2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethyl)amino)propyl)indoline-7-carboxamide. Grade: > 95%. Molecular formula: C25H32F3N3O4. Mole weight: 495.55.
(S,S)-Iso Valganciclovir Hydrochloride-d8
(S,S)-Iso Valganciclovir Hydrochloride-d8 is the isotope labelled analog of (S,S)-Iso Valganciclovir Hydrochloride. It is an impurity of valganciclovir, which is a prodrug of ganciclovir, used in the treatment of retroviruses. Synonyms: (2S)-3-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-L-valine 2-Hydroxypropyl Ester Hydrochloride-d8. Molecular formula: C14H15D8ClN6O5. Mole weight: 398.87.
(S,S)-Metalaxyl Metabolite CGA 226048
(S,S)-Metalaxyl Metabolite CGA 226048 is a metabolite of Metalaxyl. Metalaxyl is an acylalanine fungicide. Synonyms: (S)-2-[(2,6-Dimethyl-phenyl)-2-methoxyacetyl amino] propionic acid-(S)-1-methoxycarbonyl ethyl ester.
(S)-SNAP 5114
(S)-SNAP 5114 is a GABA transport inhibitor, displaying selectivity for GAT-3 and GAT-2 (IC50 = 5, 21 and 388 μM for hGAT-3, rGAT-2 and hGAT-1, respectively). (S)-SNAP 5114 was shown to increase thalamic GABA levels, and acts as an anticonvulsant following systemic administration in vivo. Uses: Anticonvulsant. Synonyms: SNAP-5114; SNAP 5114; SNAP5114; (S)-SNAP 5114; 1-[2-[tris(4-methoxyphenyl)methoxy]ethyl]-(S)-3-piperidinecarboxylic acid; (3S)-1-[2-[tris(4-methoxyphenyl)methoxy]ethyl]piperidine-3-carboxylic acid. Grade: ≥98% by HPLC. CAS No. 157604-55-2. Molecular formula: C30H35NO6. Mole weight: 505.61.
(S)-SNA-T Phosphoramidite
(S)-SNA-T Phosphoramidite is a serinol nucleic acid (SNA) analog featuring a thymine base attached to a serinol-derived backbone with (S)-stereochemistry. This structure replaces the natural ribose sugar with a serinol moiety, providing enhanced nuclease resistance and structural stability. The phosphoramidite group at the 3'-position allows for its efficient incorporation into oligonucleotides during automated synthesis. The unique backbone chemistry of SNA improves the hybridization properties of the oligonucleotides, making them highly suitable for antisense, siRNA, and other nucleic acid-based therapeutic applications, as well as for studying nucleic acid interactions in research settings. Synonyms: Phosphoramidous acid, N,N-bis(1-methylethyl)-, (2S)-3-[bis(4-methoxyphenyl)phenylmethoxy]-2-[[2-(3,4-dihydro-5-methyl-2,4-dioxo-1(2H)-pyrimidinyl)acetyl]amino]propyl 2-cyanoethyl ester; SNA T amidite. Grade: ≥98%. CAS No. 179472-04-9. Molecular formula: C40H50N5O8P. Mole weight: 759.83.
(S,S)-Palonosetron Acid
An impurity of Palonosetron which is 5-HT3 receptor blocker and works by blocking the action of serotonin in certain parts of the brain and nervous system so helps reduce or prevent nausea and vomiting. Grade: > 95%. Molecular formula: C19H26N2O2. Mole weight: 314.43.
(S,S)-Palonosetron Diethylamide Dihydrochloride
(S,S)-Palonosetron Diethylamide Dihydrochloride is an intermediate in the synthesis of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Molecular formula: C23H37Cl2N3O. Mole weight: 442.46.
(S,S)-Reboxetine
A stereoisomer of Reboxetine.Reboxetine is a norepinephrine reuptake inhibitor. It can be used for the treatment of unipolar depression, although it has also been used off-label for panic disorder and ADHD. Synonyms: [S-(R*,R*)]-2-[(2-Ethoxyphenoxy)phenylmethyl]-morpholine; (S,S)-(+)-Reboxetine; Esreboxetine; (2S)-2-[(S)-(2-Ethoxyphenoxy)phenylmethyl]-morpholine. Grade: > 95%. CAS No. 98819-76-2. Molecular formula: C19H23NO3. Mole weight: 313.4.
(S,S)-Reboxetine-d5
An isotope lablled stereoisomer of Reboxetine.Reboxetine is a norepinephrine reuptake inhibitor. It can be used for the treatment of unipolar depression, although it has also been used off-label for panic disorder and ADHD. Grade: 95% by HPLC; 98% atom D. Molecular formula: C19H18NO3D5. Mole weight: 318.43.
(S,S)-Ritalinic Acid-d5 TFA Salt
(S,S)-Ritalinic Acid-d5 TFA Salt is a labelled impurity of Ritalinic Acid. Ritalinic Acid is a metabolite of the psychostimulant drugs methylphenidate and ethylphenidate. Grade: 95% by HPLC; 98% atom D. Molecular formula: C13H12D5NO2·C2HF3O2. Mole weight: 338.33.
(S,S,R,R)-Orlistat
An impurity of Orlistat. Orlistat is a pancreatic lipase inhibitor that aids in weight loss by blocking the absorption of dietary fats in the gastrointestinal tract. Synonyms: [2R-[2α(S*),3β]]-N-Formyl-L-leucine 1-[(3-Hexyl-4-oxo-2-oxetanyl)methyl]dodecyl Ester. Grade: > 95%. CAS No. 111466-62-7. Molecular formula: C29H53NO5. Mole weight: 495.75.