BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: 2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(methylamino)-, (2E)-; Afatinib Impurity YJA. Grade: ≥95%. CAS No. 2413212-13-0. Molecular formula: C23H23ClFN5O3. Mole weight: 471.91.
(S)-Enzaplatovir
(S)-Enzaplatovir is the S-enantiomer of Enzaplatovir. It shows antiviral activities with an EC50 of 56 nM for respiratory syncytial viral (RSV). Synonyms: (S)-BTA-C585. Grade: 99%. CAS No. 1323077-88-8. Molecular formula: C20H19N5O3. Mole weight: 377.40.
[Ser(tBu)4]-Cetrorelix
[Ser(tbu)4]-Cetrorelix is a derivative of Cetrorelix, a gonadotropin-releasing hormone antagonist that can be used in the treatment of prostate and breast cancers. Synonyms: Ac-D2Nal-D4Cpa-D3Pal-Ser(tBu)-Tyr-DCit-Leu-Arg-Pro-DAla-NH2; Ser(tBu)4-Cetrorelix; Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser(tBu)-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2; Ser4(tBu)-Cetrorelix; N-Acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-O-tert-butyl-L-seryl-L-tyrosyl-D-citrullyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide; [tert-butyl-Ser4]-Cetrorelix. Grade: ≥95%. Molecular formula: C74H100ClN17O14. Mole weight: 1487.17.
(S)-Esmolol Acid
(S)-Esmolol Acid is an impurity of Esmolol. Esmolol is a cardioselective β-blocker which has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic or membrane stabilizing activities at recommended therapeutic doses. Synonyms: 4-[(2S)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzenepropanoic Acid. CAS No. 910651-36-4. Molecular formula: C15H23NO4. Mole weight: 281.35.
(S)-Esmolol Hydrochloride
(S)-Esmolol Hydrochloride is an impurity of Esmolol. Esmolol is a cardioselective β-blocker which has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic or membrane stabilizing activities at recommended therapeutic doses. Uses: The s-enantiomer of esmolol (e668000). Synonyms: 4-[(2S)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzenepropanoic Acid Methyl Ester Hydrochloride; (-)-Esmolol Hydrochloride. Grade: >95%. CAS No. 112923-91-8. Molecular formula: C16H25NO4.HCl. Mole weight: 331.83.
(S)-Etodolac
An isomer of Etodolac. Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2. Synonyms: (1S)-1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic Acid. Grade: > 95%. CAS No. 87249-11-4. Molecular formula: C17H21NO3. Mole weight: 287.36.
(S)-Fesoterodine HCl
An impurity of Fesoterodine Fumarate. Fesoterodine Fumarate is an antimuscarinic agent and is rapidly de-esterified to its active metabolite 5-hydroxymethyl tolterodine that is a muscarinic receptor antagonist. Synonyms: 2-Methylpropanoic Acid 2-[(1S)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl] -4-(hydroxymethyl)phenyl Ester HCl. Grade: > 95%. CAS No. 1294517-14-8. Molecular formula: C26H37NO3. HCl. Mole weight: 411.59 36.46.
(S)-Flurbiprofen
(S)-Flurbiprofen is the S-isomer of Flurbiprofen. Synonyms: Dexflurbiprofen; Esflurbiprofen; S-(+)-Flurbiprofen; d-Flurbiprofen; (+)-(S)-Flurbiprofen; (+)-Flurbiprofen; (2S)-2-(2-Fluoro-1,1'-biphenyl-4-yl)propanoic Acid; (2S)-2-(2-Fluoro-4-biphenyl)propanoic Acid. Grade: > 95%. CAS No. 51543-39-6. Molecular formula: C15H13FO2. Mole weight: 244.27.
(S)-Flurbiprofen Axetil (Mixture of Diastereomers)
(S)-Flurbiprofen Axetil (Mixture of Diastereomers) showcases its significant presence within the biomedical industry as a medicinal composition. Merging (S)-flurbiprofen axetil with its diastereomer, this pharmaceutical formulation serves as a robust NSAID. Synonyms: (S)-Flurbiprofen Axetil; [1,1'-Biphenyl]-4-acetic acid, 2-fluoro-α-methyl-, 1-(acetyloxy)ethyl ester, (αS)-; 1-(Acetyloxy)ethyl (αS)-2-fluoro-α-methyl[1,1'-biphenyl]-4-acetate; 1-Acetoxyethyl (2S)-2-(2-fluoro-[1,1'-biphenyl]-4-yl)propanoate. Grade: >95%. CAS No. 1401087-64-6. Molecular formula: C19H19FO4. Mole weight: 330.36.
(S)-Frovatriptan-d3 Succinate
One of the isotopic labelled isomers of Frovatriptan, which has been found to be a serotonin 5-HT1B/1D receptor agonist. Synonyms: (S)-2,3,4,9-Tetrahydro-3-(methylamino)-1H-carbazole-6-carboxamide Butanedioic Acid-d3. Molecular formula: C14H14N3OD3. C4H6O4. Mole weight: 364.42.
(S)-Frovatriptan Succinate
(S)-Frovatriptan Succinate is a potent selective serotonin receptor agonist used in the biomedical industry for the research of acute migraine attacks, derived from the succinate salt form. Grade: > 95%. Molecular formula: C18H23N3O5. Mole weight: 361.40.
(S)-gama-amino-5-(dimethylamino)-2-thiophenepropanol is a pharmaceutical compound extensively employed in the biomedical domain, playing a pivotal role in studying numerous endocrine irregularities, encompassing maladies such as diabetes and hormonal imbalances. Grade: > 95%. CAS No. 1213343-71-5. Molecular formula: C9H16N2OS. Mole weight: 200.30.
(S)-GNE-987
(S)-GNE-987, the GNE-987 (a chimeric BET degrader) hydroxy-proline epimer, abrogates binding to von Hippel-Lindau and does not degrade BRD4 protein. It binds to the BRD4 BD1 and BD2 bromodomains with IC50s of 4 and 3.9 nM, respectively. It can be used to design PROTAC-Antibody Conjugate (PAC). Synonyms: N-{11-[({7-(3,5-Difluoro-2-pyridinyl)-2-methyl-10-[(methylsulfonyl)methyl]-3-oxo-3,4,6,7-tetrahydro-2H-2,4,7-triazadibenzo[cd,f]azulen-9-yl}carbonyl)amino]undecanoyl}-3-methyl-L-valyl-(4S)-4-hydroxy-N-[4-(4-methyl-1,3-thiazol-5-yl)benzyl]-L-prolinamide; L-Prolinamide, N-[11-[[[7-(3,5-difluoro-2-pyridinyl)-3,4,6,7-tetrahydro-2-methyl-10-[(methylsulfonyl)methyl]-3-oxo-2H-2,4,7-triazadibenz[cd,f]azulen-9-yl]carbonyl]amino]-1-oxoundecyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4S)-. Molecular formula: C56H67F2N9O8S2. Mole weight: 1096.31.
(S)-Gossypol acetic acid
(S)-Gossypol acetic acid, a Bcl-2 inhibitor, could effectively induce the death of Jurkat cells in which Bcl-2 or Bcl-xL is overexpressed. IC50: 18.1μM and 22.9μM for Bcl-2 and Bcl-xL respectively. Uses: (s)-gossypol acetic acid is a bcl-2 inhibitor that could effectively induce the death of jurkat cells in which bcl-2 or bcl-xl is overexpressed. Synonyms: (S)-(+)-Gossypol acetic acid. Grade: 98%. CAS No. 1189561-66-7. Molecular formula: C32H34O10. Mole weight: 578.61.
(S)-H-1152 dihydrochloride
(S)-H-1152 dihydrochloride is a Rho-kinase inhibitor and cell permeable inhibitor of ROCK (Ki = 1.6 nM). Uses: Rho-kinase inhibitor. Synonyms: 4-Methyl-5-{[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl}isoquinoline dihydrochloride; 4-Methyl-5-{[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl}isoquinoline dihydrochloride. Grade: ≥98%. CAS No. 451462-58-1. Molecular formula: C16H21N3O2S. Mole weight: 319.42.
(S)-(-)-HA-966
(S)-(-)-HA-96 is an NMDA antagonist/partial agonist and possesses potent sedative and ataxic action. It causes disruption of striatal dopaminergic mechanisms. Synonyms: (S)-(-)-HA-966; (S)-(-)-HA 966; (S)-(-)-HA966; (S)-(-)-3-Amino-1-hydroxypyrrolidin-2-one; (3S)-3-Amino-1-hydroxypyrrolidin-2-one. Grade: ≥98% by HPLC. CAS No. 111821-58-0. Molecular formula: C4H8N2O2. Mole weight: 116.12.
(S)-HexylHIBO
(S)-HexylHIBO is a Group I mGlu receptor antagonist (Kb = 30 and 61 μM at mGlu1a and mGlu5a receptors, respectively). Synonyms: (S)-hexylhomoibotenic acid; (αS)-α-Amino-4-hexyl-2,3-dihydro-3-oxo-5-isoxazolepropanoic acid. Grade: ≥99% by HPLC. CAS No. 334887-48-8. Molecular formula: C12H20N2O4. Mole weight: 256.3.
(S)-Hydroxychloroquine
Hydroxychloroquine is a synthetic antimalarial drug, which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Synonyms: (S)-HCQ; (S)-(+)-Hydroxychloroquine; (S)-2-((4-((7-Chloroquinolin-4-yl)amino)pentyl)(ethyl)amino)ethanol. Grade: ≥98% (HPLC). CAS No. 137433-24-0. Molecular formula: C18H26ClN3O. Mole weight: 335.87.
(S)-Ibrutinib
(S)-Ibrutinib is a highly selective Bruton's tyrosine kinase (Btk) irreversible inhibitor. Synonyms: 1-[(3S)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-propen-1-one; (S)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one. Grade: > 95%. CAS No. 936563-97-2. Molecular formula: C25H24N6O2. Mole weight: 440.51.
(S)-ICMT-IN-3
(S)-ICMT-IN-3 is an inhibitor of ICMT (IC50=0.23 μM). Molecular formula: C22H29NO2. Mole weight: 339.47.
(S)-Indacaterol
An isomerous impurity of Indacaterol. Indacaterol is an ultra-long-acting β-adrenoceptor agonist used as an oral inhaled bronchodilator. It is indicated for the treatment of patients with chronic obstructive pulmonary disease (COPD). Synonyms: 5-[(1S)-2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxy-2(1H)-quinolinone. Grade: 95%. CAS No. 1235445-80-3. Molecular formula: C24H28N2O3. Mole weight: 392.499.
(S)-Isotimolol
The S-enantiomer of Ticlopidine which is an adrenergic beta-receptor blocking agent. Synonyms: Timolol Impurity B; (S)-3-[(1,1-Dimethylethyl)amino]-2-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-1-propanol. Grade: > 95%. CAS No. 158636-96-5. Molecular formula: C13H24N4O3S. Mole weight: 316.43.
(S)-Ketoprofen
(S)-Ketoprofen is a non-selective, non-steroidal, anti-inflammatory drug exhibiting IC50 values of 0.5 and 2.33 μM for human recombinant COX-1 and COX-2, respectively. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: (S)-(+)-3-Benzoyl-α-methylbenzeneacetic acid, (S)-2-(3-Benzoylphenyl)propionic acid. Grade: > 95%. CAS No. 22161-81-5. Molecular formula: C16H14O3. Mole weight: 254.29.
(S)-Ketoprofen b-D-glucuronide
(S)-Ketoprofen b-D-glucuronide is a derivative of Ketoprofen, exhibiting commendable anti-inflammatory attributes. This product has potential applications in reducing inflammation caused by arthritis or cyclic menstrual discomfort. Synonyms: β-D-Glucopyranuronic acid, 1-[(αS)-3-benzoyl-α-methylbenzeneacetate]; β-D-Glucopyranuronic acid, 1-(3-benzoyl-α-methylbenzeneacetate), (S)-; (S)-Ketoprofen glucuronide. CAS No. 140148-26-1. Molecular formula: C22H22O9. Mole weight: 430.40.
(S)-(+)-Ketoprofen-d3
An isotop labelled Ketoprofen. Ketoprofen is an analgesic drug of the nonsteroidal anti-inflammatory drug (NSAID) class used for inflammations. Synonyms: 2-(3-Benzoyl-phenyl)-propionic acid-d3. Grade: > 95%. Molecular formula: C16H11O3D3. Mole weight: 257.31.
(S)-Ketoprofen Tromethamine Salt (Dexketoprofen Trometamol)
(S)-Ketoprofen Tromethamine Salt, a modified non-selective COX inhibitor, is a non-steroidal anti-inflammatory drug used for the treatment of mild to moderate pain. Synonyms: Dexketoprofen trometamol; Benzeneacetic acid, 3-benzoyl-α-methyl-, compd. with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1), (αS)-; 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-, (S)-3-benzoyl-α-methylbenzeneacetate (salt); 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-, (αS)-3-benzoyl-α-methylbenzeneacetate (salt); Benzeneacetic acid, 3-benzoyl-α-methyl-, (S)-, compd. with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1); Benzeneacetic acid, 3-benzoyl-α-methyl-, (αS)-, compd. with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1); (S)-Ketoprofen trometamol; Dexketoprofen Tromethamine salt; Enantyum; S-(+)-Ketoprofen trometamol. Grade: ≥95%. CAS No. 156604-79-4. Molecular formula: C20H25NO6. Mole weight: 375.42.
(S)-Ketorolac
(S)-Ketorolac is a non-selective COX inhibitor and non-steroidal anti-inflammatory drug (NSAID; IC50s = 0.1 and 2.7 μM for COX-1 and COX-2, respectively). Synonyms: (-)-Ketorolac; (1S)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. Grade: ≥98%. CAS No. 66635-92-5. Molecular formula: C15H13NO3. Mole weight: 255.3.
(S)-KT109
(S)-KT109 is the S isomer of the diacylglycerol lipase β (DAGLβ) inhibitor KT109. Synonyms: (4-[1,1'-biphenyl]-4-yl-1H-1,2,3-triazol-1-yl)[(2S)-2-(phenylmethyl)-1-piperidinyl]-methanone; [(2S)-2-benzylpiperidin-1-yl]-[4-(4-phenylphenyl)triazol-1-yl]methanone. Grade: ≥98%. CAS No. 2055172-61-5. Molecular formula: C27H26N4O. Mole weight: 422.52.
(S)-Lansoprazole
The S-enantiomer of Lansoprazole; a gastric proton pump inhibitor. Synonyms: 2-[(S)-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole. Grade: > 95%. CAS No. 138530-95-7. Molecular formula: C16H14F3N3O2S. Mole weight: 369.37.
(S)-Linagliptin tert-Butyl Ester is an impurity of Linagliptin. Linagliptin is an inhibitor of dipeptidyl peptidase-4 (DPP-4) that is a medication used to treat type 2 diabetes in conjunction with exercise and diet. Synonyms: [(3S)-1-[7-(2-Butynyl)-2,3,6,7-tetrahydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-2,6-dioxo-1H-purin-8-yl]-3-piperidinyl]carbamic Acid 1,1-Dimethylethyl Ester. CAS No. 668273-74-3. Molecular formula: C30H36N8O4. Mole weight: 572.66.
(S)-Lisinopril Diethyl Ester
(S)-Lisinopril Diethyl Ester is an impurity of (S)-Lisinopril, a medication of the angiotensin-converting enzyme inhibitor class that is used to treat high blood pressure. Synonyms: N2-[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]-L-lysyl-L-proline Ethyl Ester. CAS No. 877865-60-6. Molecular formula: C25H39N3O5. Mole weight: 461.59.
(S)-Lisinopril Dimer
(S)-Lisinopril Dimer is a (S)-Lisinopril impurity. Synonyms: (S)-Lisinopril Dimer; 1356839-89-8; Lisinopril Dimer; Lisinopril EP Impurity G; Lisinopril Dimer, (S)-; AN8FVS94FZ; SCHEMBL21145466; LISINOPRIL DIHYDRATE IMPURITY G [EP IMPURITY]; (2S)-1-[(2S)-6-amino-2-{[(1S)-1-{[(5S)-5-{[(1S)-1-carboxy-3-phenylpropyl]amino}-6-[(2S)-2-carboxypyrrolidin-1-yl]-6-oxohexyl]carbamoyl}-3-phenylpropyl]amino}hexanoyl]pyrrolidine-2-carboxylic acid. Grade: > 95%. CAS No. 1356839-89-8. Molecular formula: C42H60N6O9. Mole weight: 792.96.
(S)-Lisinopril Dimer Diethyl Methyl Ester
(S)-Lisinopril Dimer Diethyl Methyl Ester is an impurity of (S)-Lisinopril, a medication of the angiotensin-converting enzyme inhibitor class that is used to treat high blood pressure. Molecular formula: C47H70N6O9. Mole weight: 863.09.
(S)-Lisinopril Methyl Ester
(S)-Lisinopril Methyl Ester is an impurity of (S)-Lisinopril, a medication of the angiotensin-converting enzyme inhibitor class that is used to treat high blood pressure. Molecular formula: C22H33N3O5. Mole weight: 419.51.
(S)-Lisofylline
(S)-Lisofylline, a chiral metabolite of pentoxifylline, acts as a potent anti-inflammatory agent. (S)-Lisofylline can interconversion with pentoxifylline. Synonyms: (S)-Lisophylline; 1-[(5S)-5-hydroxyhexyl]-3,7-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione. CAS No. 100324-80-9. Molecular formula: C13H20N4O3. Mole weight: 280.32.
(S)-Luliconazole
(S)-Luliconazole is the S-enantiomer of Luliconazole, an azole antifungal drug. Luliconazole was found to interfere with ergosterol biosynthesis in cell-free extracts of Candida albican, while no interference due to (S)-Luliconazole was found. Synonyms: (αE)-α-[(4S)-4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene]-1H-imidazole-1-acetonitrile. Grade: > 95%. CAS No. 256424-63-2. Molecular formula: C14H9Cl2N3S2. Mole weight: 354.28.
(S)-Luliconazole-Z-Isomer
(S)-Luliconazole-Z-Isomer is a potent pharmaceutical compound used in the research of fungal infections, specifically those caused by dermatophytes. It exhibits antifungal activity by inhibiting lanosterol 14α-demethylase is a key enzyme involved in ergosterol synthesis. Grade: > 95%. Molecular formula: C14H9Cl2N3S2. Mole weight: 354.28.
(S)-Mapracorat
(S)-Mapracorat is a selective and less active agonist of glucocorticoid receptor. Synonyms: (S)-ZK-245186; (S)-BOL-303242X; 7-Benzofuranpropanol, 5-fluoro-2,3-dihydro-γ,γ-dimethyl-α-[[(2-methyl-5-quinolinyl)amino]methyl]-α-(trifluoromethyl)-, (αS)-; (2S)-1,1,1-Trifluoro-4-(5-fluoro-2,3-dihydro-1-benzofuran-7-yl)-4-methyl-2-{[(2-methyl-5-quinolinyl)amino]methyl}-2-pentanol. Grade: ≥95%. CAS No. 887375-15-7. Molecular formula: C25H26F4N2O2. Mole weight: 462.48.
(S)-MCPG
(S)-MCPG, the active isomer of (RS)-MCPG, is a non-selective group I/group II mGluR antagonist. Synonyms: (S)-α-Methyl-4-carboxyphenylglycine; (+)-MCPG; 4-[(1S)-1-amino-1-carboxyethyl]benzoic acid. Grade: ≥99% by HPLC. CAS No. 150145-89-4. Molecular formula: C10H11NO4. Mole weight: 209.2.
(S)-(+)-Mephenytoin
(S)-(+)-Mephenytoin is an S-isomer of Mephenytoin, which is known to target sodium channel protein type 5 subunit alpha. Mephenytoin is a hydantoin-derivative anticonvulsant used to control various partial seizures. It is a substrate of the cytochrome P450 (CYP) isoform CYP2C19. It can be used to screen for such mutations by assaying its metabolites in urine. Synonyms: (S)-5-Ethyl-3-methyl-5-phenylhydantoin; (+)-Mephenytoin; (5S)-5-Ethyl-3-methyl-5-phenyl-2,4-imidazolidinedione. Grade: > 95%. CAS No. 70989-04-7. Molecular formula: C12H14N2O2. Mole weight: 218.26.
(S)-Methyl 1-((S)-2-(((S)-1-(Benzyloxy)-1-oxo-4-phenylbutan-2-yl)amino)-6-(((benzyloxy)carbonyl)amino)hexanoyl)pyrrolidine-2-carboxylate is an intermediate in the synthesis of Lisinopril, which is an angiotensin-converting enzyme inhibitor used in the treatment of hypertension, congestive heart failure, and heart attacks. Synonyms: Methyl N6-[(benzyloxy)carbonyl]-N2-[(2S)-1-(benzyloxy)-1-oxo-4-phenyl-2-butanyl]-L-lysyl-L-prolinate; L-Proline, N6-[(phenylmethoxy)carbonyl]-N2-[(1S)-3-phenyl-1-[(phenylmethoxy)carbonyl]propyl]-L-lysyl-, methyl ester. Molecular formula: C37H45N3O7. Mole weight: 643.77.
(S)-methyl 2-(2-chlorophenyl)-2-(2-(hydroxymethyl)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate is an impurity of Clopidogrel, an antithrombotic agent. Synonyms: Clopidogrel Bisulfate Impurity 29. CAS No. 1346231-35-3. Molecular formula: C17H18ClNO3S. Mole weight: 351.85.
An impurity of Valsartan. Valsartan is an antagonist of angiotensin II receptor mainly used for the treatment of high blood pressure and congestive heart failure. Synonyms: L-Valine, N-[(2'-cyano[1,1'-biphenyl]-4-yl)methyl]-, methyl ester; N-[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]-L-valine methyl ester; N-[(2'-Cyano-(1,1'-biphenyl)-4-yl)methyl)]valine methyl ester; Valsartan impurity D. Grade: ≥95%. CAS No. 137863-89-9. Molecular formula: C20H22N2O2. Mole weight: 322.41.
An impurity of Valsartan. Valsartan is an antagonist of angiotensin II receptor mainly used for the treatment of high blood pressure and congestive heart failure. Synonyms: L-Valine, N-[(2'-cyano[1,1'-biphenyl]-4-yl)methyl]-, methyl ester, hydrochloride (1:1); L-Valine, N-[(2'-cyano[1,1'-biphenyl]-4-yl)methyl]-, methyl ester, monohydrochloride; N-[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]-L-valine methyl ester hydrochloride (1:1); N-[2'-Cyanobiphenyl-4-yl-methyl]-(L)-valine methyl ester hydrochloride. Grade: ≥95%. CAS No. 482577-59-3. Molecular formula: C20H23ClN2O2. Mole weight: 358.86.
(S)-Methyl 3-amino-4-(2,4,5-trifluorophenyl)butanoate Tartaric acid salt
(S)-Methyl 3-amino-4-(2,4,5-trifluorophenyl)butanoate Tartaric acid salt is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: Benzenebutanoic acid, β-amino-2,4,5-trifluoro-, methyl ester, (βR)-, (2R,3R)-2,3-dihydroxybutanedioate (1:1); Sitagliptin Impurity 85. CAS No. 1384431-02-0. Molecular formula: C15H18F3NO8. Mole weight: 397.30.
(S)-Metoprolol
(S)-Metoprolol is the (S)-Enantiomer of Metoprolol, a β1 receptor blocker medication. Synonyms: (2S)-1-[4-(2-Methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-2-propanol; (-)-Metoprolol; (S)-(-)-Metoprolol. Grade: > 95%. CAS No. 81024-42-2. Molecular formula: C15H25NO3. Mole weight: 267.36.
(S)-Mirtazapine-13C-d3
(S)-Mirtazapine-13C-d3 is a labelled (S)-Mirtazapine. Mirtazapine is a medication used for the treatment of depression. It can improve mood via restoring the balance of neurotransmitters in the CNS. Grade: > 95%. Molecular formula: C17H16N3D3. Mole weight: 269.37.
(S)-Mosapride citrate
(S)-Mosapride citrate is an impurity of Mosapride. Mosapride is a 5-HT4 receptor agonist and 5-HT3 receptor antagonist. It is used as a gastroprokinetic agent. Synonyms: Benzamide, 4-amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]-2-morpholinyl]methyl]-, (S)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1); 4-Amino-5-chloro-2-ethoxy-N-{[(2S)-4-(4-fluorobenzyl)-2-morpholinyl]methyl}benzamide 2-hydroxy-1,2,3-propanetricarboxylate (1:1); (S)-4-amino-5-chloro-2-ethoxy-N-((4-(4-fluorobenzyl)morpholin-2-yl)methyl)benzamide citrate. Grade: ≥95%. CAS No. 156925-25-6. Molecular formula: C21H25ClFN3O3.C6H8O7. Mole weight: 614.02.
(S)-Mycophenolic acid lactone
An impurity of Mycophenolate Mofetil. Mycophenolate Mofetil is an immunosuppressive agent used primarily to prevent organ rejection in patients who have undergone kidney, liver, or heart transplants. Uses: A degradation product of mycophenolic acid. ep impurity h. Synonyms: (S)-7-Hydroxy-5-methoxy-4-methyl-6-(2-(2-methyl-5-oxotetrahydrofuran-2-yl)ethyl)isobenzofuran-1(3H)-one. CAS No. 79081-87-1. Molecular formula: C17H20O6. Mole weight: 320.34.
(S)-N-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)acetamide is an impurity of Apremilast, which is an oral phosphodiesterase 4 inhibitor used for treating psoriatic arthritis. Synonyms: (S)-N-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)acetamide; SCHEMBL15198848; 2097600-16-1. CAS No. 2097600-16-1. Molecular formula: C14H21NO5S. Mole weight: 315.38.
(S)-N-(2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-5-yl)acetamide is an impurity of Apremilast, which is an oral phosphodiesterase 4 inhibitor used for treating psoriatic arthritis. CAS No. 2201974-01-6. Molecular formula: C22H24N2O7S. Mole weight: 460.50.
(S)-N-[2-[2,3-Dihydro-6-hydroxy-7-(2-hydroxyethyl)-1H-inden-1-yl]ethyl]propanamide is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Uses: Intermediate in the production of ramelteon. Synonyms: N-[2-[(1S)-2,3-Dihydro-6-hydroxy-7-(2-hydroxyethyl)-1H-inden-1-yl]ethyl]propanamide; (S)-N-[2-(6-Hydroxy-7-(2-hydroxyethyl)-2,3-dihydro-1H-iden-1-yl)ethyl]propionamide. Grade: >95%. CAS No. 196597-88-3. Molecular formula: C16H23NO3. Mole weight: 277.36.
(S)-N-[2-(2,3-Dihydro-6-methoxy-1H-inden-1-yl)ethyl]propanamide is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Uses: Intermediate in the production of ramelteon. Synonyms: N-[2-[(1S)-2,3-Dihydro-6-methoxy-1H-inden-1-yl]ethyl]propanamide. CAS No. 178678-16-5. Molecular formula: C15H21NO2. Mole weight: 247.33.
(S)-N-[2-(5-Bromo-2,3-dihydro-6-hydroxy-1H-inden-1-yl)ethyl]propanamide is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Uses: Intermediate in the production of ramelteon. Synonyms: (S)-N-[2-(5-bromo-6-hydroxyindan-1-yl)ethyl]propionamide. CAS No. 196597-84-9. Molecular formula: C14H18BrNO2. Mole weight: 312.2.
(S)-N-[2-(5-Bromo-2,3-dihydro-6-methoxy-1H-inden-1-yl)ethyl]propanamide is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Synonyms: (S)-N-[2-(5-bromo-6-methoxyindan-1-yl)ethyl]propionamide; N-[2-[(1S)-5-Bromo-2,3-dihydro-6-methoxy-1H-inden-1-yl]ethyl]propanamide; Propanamide, N-[2-[(1S)-5-bromo-2,3-dihydro-6-methoxy-1H-inden-1-yl]ethyl]-; Propanamide, N-[2-(5-bromo-2,3-dihydro-6-methoxy-1H-inden-1-yl)ethyl]-, (S)-. Grade: ≥95%. CAS No. 196597-83-8. Molecular formula: C15H20BrNO2. Mole weight: 326.23.
(S)-N-[2-[6-Allyloxy-5-bromo-2,3-dihydro-1H-inden-1-yl]ethyl]propanamide is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Synonyms: N-[2-[(1S)-5-Bromo-6-(ethenyloxy)-2,3-dihydro-1H-inden-1-yl]ethyl]propanamide. CAS No. 1246820-28-9. Molecular formula: C16H20BrNO2. Mole weight: 338.24.
(S)-N-(2,6-Dimethylphenyl)-2-(4-(2-hydroxy-3-((2-methoxyphenyl)amino)propyl)piperazin-1-yl)acetamide is one of Ranolazine impurities. Ranolazine is an anti-ischemic agent which modulates myocardial metabolism. Molecular formula: C24H34N4O3. Mole weight: 426.55.
(S)-N-[2-[7-Allyl-5-bromo-2,3-dihydro-6-hydroxy-1H-inden-1-yl]ethyl]propanamide is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Uses: Intermediate in the production of ramelteon. Synonyms: (S)-N-[2-[5-Bromo-2,3-dihydro-6-hydroxy-7-(2-propenyl)-1H-inden-1-yl]ethyl]propanamide; (S)-N-[2-(7-allyl-5-bromo-6-hydroxyindan-1-yl)ethyl] propionamide. CAS No. 196597-86-1. Molecular formula: C17H22BrNO2. Mole weight: 352.27.
(S)-N-[2-[7-Allyl-5-bromo-6-benzyloxy-2,3-dihydro-1H-inden-1-yl]ethyl]propanamide is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Synonyms: (S)-N-(2-(7-allyl-6-(benzyloxy)-5-bromo-2,3-dihydro-1H-inden-1-yl)ethyl)propionamide. CAS No. 1246820-29-0. Molecular formula: C24H28BrNO2. Mole weight: 442.39.
(S)-N-((3-(3-fluoro-4-(2H-1,4-oxazin-4(3H)-yl)phenyl)-2-oxooxazolidin-5-yl)methyl)acetamide is an impurity of Linezolid, an oxazolidinone antimicrobial that is used to treat infections against gram-positive bacteria, especially those that are drug-resistant. Linezolid works by inhibiting bacterial protein synthesis. Synonyms: Acetamide, N-[[(5S)-3-[4-(2,3-dihydro-4H-1,4-oxazin-4-yl)-3-fluorophenyl]-2-oxo-5-oxazolidinyl]methyl]-; Linezolid Impurity 39. CAS No. 1997296-64-6. Molecular formula: C16H18FN3O4. Mole weight: 335.33.
(S)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)propionamide is an impurity of Linezolid, an oxazolidinone antimicrobial that is used to treat infections against gram-positive bacteria, especially those that are drug-resistant. Linezolid works by inhibiting bacterial protein synthesis. Synonyms: Linezolid Impurity 08. CAS No. 216869-17-9. Molecular formula: C17H22FN3O4. Mole weight: 351.37.
An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: 4,6-Quinazolinediamine, N4-(4-fluorophenyl)-7-[[(3S)-tetrahydro-3-furanyl]oxy]; Afatinib Impurity P. Grade: ≥95%. CAS No. 2413212-07-2. Molecular formula: C18H17FN4O2. Mole weight: 340.35.
(S)-N-[6-Benzyloxy-5-bromo-7-(2-hydroxyethyl)-2,3-dihydro-1H-inden-1-ylidene)ethyl]propanamide is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Synonyms: N-[2-[(1S)-5-Bromo-2,3-dihydro-7-(2-hydroxyethyl)-6-(phenylmethoxy)-1H-inden-1-yl]ethyl]propanamide. Grade: >95%. CAS No. 1246820-32-5. Molecular formula: C23H28BrNO3. Mole weight: 446.38.
(S)-Naproxen acyl-b-D-glucuronide benzyl ester
(S)-Naproxen acyl-b-D-glucuronide benzyl ester is a potent biomedicine used in the treatment of inflammation, pain, and various forms of arthritis. It exhibits anti-inflammatory and analgesic activities by inhibiting cyclooxygenase enzymes. This product acts as a prodrug, converting into active Naproxen within the body. It is commonly used in pharmaceutical research and development to study the metabolism and pharmacokinetics of Naproxen derivatives. Synonyms: β-D-Glucopyranuronic acid, phenylmethyl ester, 1-[(αS)-6-methoxy-α-methyl-2-naphthaleneacetate]; Naproxen acyl-β-D-glucuronide benzyl ester. CAS No. 946517-36-8. Molecular formula: C27H28O9. Mole weight: 496.51.
(S)-Naproxen Iso-acyl-β-D-glucuronide
(S)-Naproxen Iso-acyl-β-D-glucuronide is the metabolite of Naproxen, which is a non-selective COX inhibitor used for the treatment of rheumatoid arthritis and gout. Synonyms: β-D-Glucopyranuronic acid, 4-[(αS)-6-methoxy-α-methyl-2-naphthaleneacetate]; 4-((αS)-6-Methoxy-α-methyl-2-naphthaleneacetate) β-D-glucopyranuronic acid; (2S,3S,4R,5R,6R)-4,5,6-Trihydroxy-3-(((S)-2-(6-methoxynaphthalen-2-yl)propanoyl)oxy)tetrahydro-2H-pyran-2-carboxylic acid; Naproxen Iso-acyl-β-D-glucuronide. Grade: ≥98%. CAS No. 219476-92-3. Molecular formula: C20H22O9. Mole weight: 406.38.
(S)-N-Desethyl N-Benzyl Oxybutynin
(S)-N-Desethyl N-Benzyl Oxybutynin is an impurity of oxybutynin, which is an inhibitor of proliferation and supresses gene expression in bladder smooth muscle cells. Synonyms: (S)-4-(Benzyl(ethyl)amino)but-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate. Molecular formula: C27H33NO3. Mole weight: 419.55.
(S)-N-Desmethyl Duloxetine Hydrochloride
(S)-N-Desmethyl Duloxetine Hydrochloride is an impurity of Duloxetine, which is a serotonin-norepinephrine reuptake inhibitor used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, neuropathic pain and central sensitization. Synonyms: (γS)-γ-(1-Naphthalenyloxy)-2-thiophenepropanamine Hydrochloride; (S)-γ-(1-Naphthalenyloxy)-2-thiophenepropanamine Hydrochloride; (3S)-3-(1-Naphthyloxy)-3-(2-thienyl)-1-propanamine hydrochloride (1:1); 2-Thiophenepropanamine, γ-(1-naphthalenyloxy)-, (γS)-, hydrochloride (1:1). CAS No. 1798887-69-0. Molecular formula: C17H18ClNOS. Mole weight: 319.85.
(S)-N-Didemethyl Dapoxetine
(S)-N-Didemethyl Dapoxetine is an impurity of Dapoxetine. Dapoxetine HCl is a novel short-acting selective serotonin reuptake inhibitor. Uses: The (s)-metabolite of dapoxetine (d185700). selective serotonin reuptake inhibitor antidepressant. Synonyms: (S)-α-[2-(1-Naphthalenyloxy)ethyl]benzenemethanamine. CAS No. 147199-40-4. Molecular formula: C19H19NO. Mole weight: 277.36.