BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
(S)-2-(((tert-Butyldimethylsilyl)-oxy)diphenylmethyl)pyrrolidine is a derivative of Diphenylprolinol, which is a norepinephrine-dopamine reuptake inhibitor used as a designer drug. Synonyms: (S)-[t-Butyldimethylsiloxy)-diphenylmethyl]pyrrolidine; (2S)-2-[{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}(diphenyl)methyl]pyrrolidine; (S)-(-)-α,α-Diphenylprolinol tert-butyldimethylsilyl ether; Pyrrolidine, 2-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]diphenylmethyl]-, (2S)-; (2S)-2-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]diphenylmethyl]pyrrolidine. Grade: ≥97%. CAS No. 864466-71-7. Molecular formula: C23H33NOSi. Mole weight: 367.60.
(S)-3-((3aR,5R,6S,6aR)-6-(Benzyloxy)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)propane-1,2-diol is an indispensable constituent in the biomedical sector, owing to its pivotal role as a significant precursor in the preparation of a host of pharmacologically active compounds. Its versatile and unique structure makes it an ideal synthetic building block for natural product derivatives, thereby opening up new avenues for the treatment and management of a broad spectrum of maladies such as cancer, viral infections, and neurological disorders. The interplay of its functional groups makes it a potent therapeutic agent with immense potential for the alleviation of human suffering. CAS No. 871347-98-7. Molecular formula: C17H24O6. Mole weight: 324.4.
(S)-(3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl methanesulfonate is an impurity of Linezolid, an oxazolidinone antimicrobial that is used to treat infections against gram-positive bacteria, especially those that are drug-resistant. Linezolid works by inhibiting bacterial protein synthesis. Synonyms: Linezolid Impurity 28. CAS No. 2180621-71-8. Molecular formula: C15H19FN2O6S. Mole weight: 374.38.
(S)-3-(3-fluoro-4-morpholinophenyl)-5-(hydroxymethyl)oxazolidin-2-one is an impurity of Linezolid, an oxazolidinone antimicrobial that is used to treat infections against gram-positive bacteria, especially those that are drug-resistant. Linezolid works by inhibiting bacterial protein synthesis. Synonyms: 2-Oxazolidinone, 3-[3-fluoro-4-(4-morpholinyl)phenyl]-5-(hydroxymethyl)-, (5S); Linezolid Impurity 24. CAS No. 2180529-06-8. Molecular formula: C14H17FN2O4. Mole weight: 296.29.
(S)-3-(4-(5-bromo-2-chlorobenzyl)phenoxy)tetrahydrofuran is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: (3S)-3-[4-[(5-Bromo-2-chlorophenyl)methyl]phenoxy]tetrahydrofuran; Empagliflozin Impurity I. CAS No. 915095-89-5. Molecular formula: C17H16BrClO2. Mole weight: 367.66.
(S)-3-(4-Chlorophenyl)-4-hydroxybutyric Acid Sodium Salt
(S)-3-(4-Chlorophenyl)-4-hydroxybutyric Acid Sodium Salt is a metabolite of Baclofen, which is a specific GABA-B receptor agonist with muscle relaxant effect. Synonyms: (S)-β-(p-Chlorophenyl)-γ-hydroxybutyric Acid Sodium Salt; (S)-4-Chloro-β-(hydroxymethyl)benzenepropanoic Acid Sodium Salt. Grade: 98%. CAS No. 1346617-13-7. Molecular formula: C10H10ClNaO3. Mole weight: 236.63.
(S)-3,4-Dihydro-5,12-dihydroxy-7-methoxy-4-[[2,3,6-trideoxy-3-[(trifluoroacetyl)amino]-α-L-lyxo-hexopyranosyl]oxy]-2,6,11(1H)-naphthacenetrione is an intermediate in the synthesis of Feudomycin B, an anthracycline metabolite produced via Streptomyces biosynthesis. Synonyms: 2,6,11(1H)-Naphthacenetrione, 3,4-dihydro-5,12-dihydroxy-7-methoxy-4-[[2,3,6-trideoxy-3-[(trifluoroacetyl)amino]-α-L-lyxo-hexopyranosyl]oxy]-, (S)-. CAS No. 64882-10-6. Molecular formula: C27H24F3NO10. Mole weight: 579.48.
An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Synonyms: Ibrutinib impurity SYGIM. Grade: ≥95%. CAS No. 1642630-12-3. Molecular formula: C22H22N6O. Mole weight: 386.45.
(S)-3',5'-Bis(trifluoromethyl)-1-phenethanol
(S)-3',5'-Bis(trifluoromethyl)-1-phenethanol is an intermediate of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Uses: Aprepitant intermediate. Synonyms: (αS)-α-Methyl-3,5-bis(trifluoromethyl)benzenemethanol; (S)-3,5-Bis(trifluoromethyl) Phenethyl Alcohol; (S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol; (S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethan-1-ol; (1S)-(-)-1-[3,5-Bis(trifluoromethyl)phenyl]ethan-1-ol; Benzenemethanol, α-methyl-3,5-bis(trifluoromethyl)-, (αS)-. Grade: ≥95%. CAS No. 225920-05-8. Molecular formula: C10H8F6O. Mole weight: 258.16.
(S)-3,5-DHPG
(S)-3,5-DHPG is a selective group I mGluR agonist used for the treatment of neuronal injury and cognitive enhancement. Uses: The treatment of neuronal injury and cognitive enhancement. Synonyms: (S)-3,5-Dihydroxyphenylglycine; (2S)-2-amino-2-(3,5-dihydroxyphenyl)acetic acid. Grade: ≥98% by HPLC. CAS No. 162870-29-3. Molecular formula: C8H9NO4. Mole weight: 183.16.
(S)-3-acetamido-2-((1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)carbamoyl)benzoic acid is an impurity of Apremilast, which is an oral phosphodiesterase 4 inhibitor used for treating psoriatic arthritis. Synonyms: 3-Acetamido-2-{[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]carbamoyl}benzoic acid. CAS No. 2096492-41-8. Molecular formula: C22H26N2O8S. Mole weight: 478.52.
(S)-3-Amino-2-piperidone hydrochloride
Ornithine-1,5-Lactam HCl, is an building block , used in the synthesis of various pharmaceutical compounds. Synonyms: (3S)-3-aminopiperidin-2-one; hydrochloride. Grade: 96 %. CAS No. 42538-31-8. Molecular formula: C5H11ClN2O. Mole weight: 150.61.
(S)-3'-amino Blebbistatin
(S)-3'-amino Blebbistatin is a more stable and less phototoxic form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. Synonyms: (-)-3'-amino Blebbistatin; m-amino Blebbistatin; meta-amino Blebbistatin; (3aS)-1-(3-aminophenyl)-1,2,3,3a-tetrahydro-3a-hydroxy-6-methyl-4H-pyrrolo[2,3-b]quinolin-4-one. Grade: ≥95%. CAS No. 2097141-18-7. Molecular formula: C18H17N3O2. Mole weight: 307.35.
(S)-3-Amino-piperidine-2,6-dione
(S)-3-Amino-piperidine-2,6-dione Hydrochloride can be used as anticancer agents. Synonyms: Aminoglutarimide, L-2-. Grade: 97.0 %. CAS No. 29883-25-8. Molecular formula: C5H8N2O2. Mole weight: 128.13.
(S)-3-aminotetrahydrothiophene 1,1-dioxide hydrochloride is an important sulfur-containing heterocyclic compounds. It is widely used as building blocks in many agrochemicals, materials science and pharmaceuticals. Uses: (s)-3-aminotetrahydrothiophene 1,1-dioxide hydrochloride is widely used as building blocks in many agrochemicals, materials science and pharmaceuticals. Synonyms: (3S)-3-ThiophenaMine, tetrahydro-, 1,1-dioxide, hydrochloride; (3S)-1,1-dioxothiolan-3-amine hydrochloride. Grade: >98 %. CAS No. 935455-28-0. Molecular formula: C4H10ClNO2S. Mole weight: 171.65.
(S)-3-Carboxy-4-hydroxyphenylglycine
(S)-3-Carboxy-4-hydroxyphenylglycine has been found to be a mixed group II mGlu agonist as well as group I metabotropic glutamate receptor antagonist. Synonyms: (S)-5-(amino(carboxy)methyl)-2-hydroxybenzoic acid. Grade: ≥98% by HPLC. CAS No. 55136-48-6. Molecular formula: C9H9NO5. Mole weight: 211.17.
An impurity of Rivaroxaban. Rivaroxaban inhibits both free Factor Xa and Factor Xa bound in the prothrombinase complex. It is a highly selective direct Factor Xa inhibitor with oral bioavailability and rapid onset of action. Synonyms: 2-Thiophenecarboxamide, 3-chloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-; Rivaroxaban Impurity 21. CAS No. 1855920-54-5. Molecular formula: C19H18ClN3O5S. Mole weight: 435.88.
(S)-3-(dimethylamino)-1-(thiophen-3-yl)propan-1-ol is an impurity of Duloxetine, an antidepressant medication used to treat major depressive disorder. Synonyms: rac-alpha-[2-(Dimethylamino)ethyl]-3-thiophenemethanol. CAS No. 1384080-56-1. Molecular formula: C9H15NOS. Mole weight: 185.29.
(S)-3'-hydroxy Blebbistatin
(S)-3'-hydroxy Blebbistatin is a more stable and less phototoxic form of (-)-blebbistatin , which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. Synonyms: (-)-3'-hydroxy Blebbistatin; meta-hydroxy-Blebbistatin; m-hydroxy-Blebbistatin; 1,2,3,3aS-tetrahydro-3a-hydroxy-1-(3-hydroxyphenyl)-6-methyl-4H-pyrrolo[2,3-b]quinolin-4-one. Grade: ≥95%. CAS No. 2097136-42-8. Molecular formula: C18H16N2O3. Mole weight: 308.33.
(S)-3-Hydroxy Midostaurin
(S)-3-Hydroxy Midostaurin, a potent kinase inhibitor with IC50s of <400 nM for 13 kinases (VEGFR-2, TRK-A, FLT3, et), is a minor metabolite of midostaurin undergoing by the hepatic CYP3A4 enzyme. It has the potential for the treatment of acute myeloid leukemia (AML). Synonyms: (S)-CGP52421; Benzamide, N-((3S,9S,10R,11R,13R)-2,3,10,11,12,13-hexahydro-3-hydroxy-10-methoxy-9-methyl-1-oxo-9,13-epoxy-1H,9H-diindolo(1,2,3-gh:3',2',1'-lm)pyrrolo(3,4-j)(1,7)benzodiazonin-11-yl)-N-methyl-; 3-Hydroxy Midostaurin Epimer 1; CGP52421 Epimer 1. Grade: ≥95%. CAS No. 945260-14-0. Molecular formula: C35H30N4O5. Mole weight: 586.64.
(S)-3-Hydroxyphenylglycine
(S)-3-Hydroxyphenylglycine is an agonist at group I metabotropic glutamate receptors (mGlu1) with no effect at mGlu2 or mGlu4. Synonyms: (2S)-2-Amino-2-(3-hydroxyphenyl)acetic acid. Grade: ≥99% by HPLC. CAS No. 71301-82-1. Molecular formula: C8H9NO3. Mole weight: 167.16.
(S)-3''-Hydroxypravastatin sodium salt
An impurity of Pravastatin. Pravastatin is a member of the drug class of statins. It can be used for lowering cholesterol and preventing cardiovascular disease. Synonyms: (S)-3''-Hydroxy Pravastatin Sodium Salt; 1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-β,δ,6-trihydroxy-8-[(2S,3S)-3-hydroxy-2-methyl-1-oxobutoxy]-2-methyl-, sodium salt (1:1), (βR,δR,1S,2S,6S,8S,8aR)-; Pravastatin Sodium EP Impurity E sodium salt; Pravastatin EP Impurity E sodium salt; Pravastatin Impurity E sodium salt; 3''-(S)-Hydroxypravastatin sodium salt; (βR,δR,1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-β,δ,6-trihydroxy-8-[(2S,3S)-3-hydroxy-2-methyl-1-oxobutoxy]-2-methyl-1-naphthaleneheptanoic acid sodium salt. Grade: >95%. CAS No. 722504-45-2. Molecular formula: C23H35NaO8. Mole weight: 462.52.
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L17) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (4S)-3-[(2R)-2-[(S)-[4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]phenyl][(4-fluorophenyl)amino]methyl]-4-[2-(4-fluorophenyl)-5,5-dimethyl-1,3-dioxan-2-yl]-1-oxobutyl]-4-phenyl-2-oxazolidinone; Ezetimibe Impurity U. CAS No. 1478663-95-4. Molecular formula: C44H52F2N2O6Si. Mole weight: 770.98.
(S)-(3R,4R,5S,6R)-3,4-Dihydroxy-6-(hydroxymethyl)-5-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl 2,2,5,5-tetramethylthiazolidine-4-carboxylate is a pharmacological intermediate used in the manufacturing of drugs used to treat cardiovascular and metabolism related diseases. Synonyms: 4-O-β-D-Galactopyranosyl-1-O-{[(4S)-2,2,5,5-tetramethyl-1,3-thiazolidin-4-yl]carbonyl}-D-glucopyranose; D-Glucopyranose, 4-O-β-D-galactopyranosyl-1-O-[[(4S)-2,2,5,5-tetramethyl-4-thiazolidinyl]carbonyl]-. Molecular formula: C20H35NO12S. Mole weight: 513.56.
(S)-3-((tert-butoxycarbonyl)amino)-4-(2,5-difluorophenyl)butanoic acid is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: Sitagliptin Impurity 24; Benzenebutanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-2,5-difluoro-, (βS)-. CAS No. 2349567-54-8. Molecular formula: C15H19F2NO4. Mole weight: 315.32.
An impurity of Rivaroxaban. Rivaroxaban inhibits both free Factor Xa and Factor Xa bound in the prothrombinase complex. It is a highly selective direct Factor Xa inhibitor with oral bioavailability and rapid onset of action. Synonyms: 4-[4-[[(2S)-3-Amino-2-hydroxypropyl]amino]phenyl]-3-morpholinone; Rivaroxaban Impurity 20; Rivaroxaban Impurity 41. Grade: 98% by HPLC. CAS No. 1403383-56-1. Molecular formula: C13H19N3O3. Mole weight: 265.31.
An impurity of Rivaroxaban. Rivaroxaban inhibits both free Factor Xa and Factor Xa bound in the prothrombinase complex. It is a highly selective direct Factor Xa inhibitor with oral bioavailability and rapid onset of action. CAS No. 1403383-55-0. Molecular formula: C13H20ClN3O3. Mole weight: 301.77.
(S)-4,6-O-ethylidene-1,2-O-(1-methylethylidene)-α-D-galactopyranose is an intermediate used in the synthesis of D-Galactose-3-sulfate Sodium Salt, which is an D-Galactose sulfated conjugate, an epimer of Glucose that is found in milk and sugar beets as well as being synthesized by the body. Synonyms: α-D-Galactopyranose, 4,6-O-ethylidene-1,2-O-(1-methylethylidene)-, (S)-. CAS No. 112711-30-5. Molecular formula: C11H18O6. Mole weight: 246.26.
An impurity of Brinzolamide, a potent carbonic anhydrase inhibitor used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension. CAS No. 2183841-60-1. Molecular formula: C10H17N3O5S3. Mole weight: 355.45.
(S)-(-)-4-Amino-2-hydroxybutyric AcidAmikacin EP Impurity I
(S)-(-)-4-Amino-2-hydroxybutyric acid is an analogue of γ-aminobutyric acid (GABA) that exhibits potential inhibitory activity on GABA binding and uptake by brain. Synonyms: (2S)-4-Amino-2-hydroxybutanoic Acid; (S)-4-Amino-2-hydroxybutanoic Acid; (S)-4-Amino-2-hydroxybutyric Acid; 4-Amino-(2S)-hydroxybutyric Acid; L-(-)-4-Amino-2-hydroxybutyric Acid; L-(-)-γ-Amino-α-hydroxybutyric Acid; L-4-Amino-2-hydroxybutyric Acid; L-γ-Amino-α-hydroxybutyric Acid; (S)-(-)-4-Amino-2-hydroxybutyric Acid. Grade: 95%. CAS No. 40371-51-5. Molecular formula: C4H9NO3. Mole weight: 119.12.
(S)-4-Carboxy-3-hydroxyphenylglycine
(S)-4C3H-PG has been found to be a competitive GluR1 glutamate receptor antagonist as well as metabotropic GluR2/3 glutamate receptor agonist. Synonyms: (S)-4C3H-PG. Grade: ≥98% by HPLC. CAS No. 85148-82-9. Molecular formula: C9H9NO5. Mole weight: 211.17.
(S)-4-Carboxyphenylglycine
(S)-4-Carboxyphenylglycine has been found to be a competitive group I metabotropic glutamate receptor antagonist(S)-4-Carboxyphenylglycine has been found to be a competitive group I metabotropic glutamate receptor antagonist and selective for mGluR1. Synonyms: (S)-4CPG; (S)-4C-PG; (S)-4-Carboxyphenylglycine; (S)-4C-PG; (αS)-α-Amino-4-carboxybenzeneacetic Acid. Grade: ≥99% by HPLC. CAS No. 134052-73-6. Molecular formula: C9H9NO4. Mole weight: 195.17.
An impurity of Rivaroxaban. Rivaroxaban inhibits both free Factor Xa and Factor Xa bound in the prothrombinase complex. It is a highly selective direct Factor Xa inhibitor with oral bioavailability and rapid onset of action. Synonyms: Rivaroxaban Impurity 22. CAS No. 1350288-77-5. Molecular formula: C19H18ClN3O5S. Mole weight: 435.88.
(S)-4-hydroxy-2-pyrrolidinone-1-N-acetic acid
(S)-4-Hydroxy-2-pyrrolidinone-1-N-acetic acid is an impurity or a related compound of oxiracetam, which is a nootropic drug to improve memory and learning. Synonyms: (4S)-4-Hydroxy-2-oxo-1-pyrrolidineacetic Acid; (S)-2-(4-Hydroxy-2-oxopyrrolidin-1-yl)acetic Acid; (S)-(4-Hydroxy-2-oxopyrrolidin-1-yl)-acetic acid; 1-pyrrolidineacetic acid, 4-hydroxy-2-oxo-, (4S)-; (S)-4-hydroxy-2-pyrrolidinone-1-nacetic acid. Grade: 95%. CAS No. 99437-11-3. Molecular formula: C6H9NO4. Mole weight: 159.14.
(S)-4-Hydroxy Mephenytoin
The S-enantiomer metabolite of Mephenytoin which is used as an anticonvulsant. Synonyms: (S)-4-Hydroxy Mephenytoin; 82695-93-0; (5S)-5-Ethyl-5-(4-hydroxyphenyl)-3-methylimidazolidine-2,4-dione; 4'-hydroxymephenytoin; SCHEMBL14067600; DTXSID20654509; CHEBI:196007; (S)-5-Ethyl-5-(4-hydroxyphenyl)-3-methyl-2,4-imidazolidinedione; 5S)-5-Ethyl-5-(4-hydroxyphenyl)-3-methyl-2,4-imidazolidinedione. Grade: > 95%. CAS No. 82695-93-0. Molecular formula: C12H14N2O3. Mole weight: 234.26.
(S)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-2-(pyrimidin-5-yl)-1,2,3,4-tetrahydroisoquinoline-7-carboxamide is an effective Erv1/ALR inhibitor with IC50 values of 900 nM and 700 nM, respectively. It also inhibits Erv2 (IC50 = 1.4 μM) and can induce apoptosis of hESCs cells through the release of cytochrome c. Synonyms: 7-Isoquinolinecarboxamide, 1,2,3,4-tetrahydro-4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-2-(5-pyrimidinyl)-, (4S)-. Grade: >98.0%. CAS No. 1934246-20-4. Molecular formula: C26H23F3N6O. Mole weight: 492.5.
(S)-4'-nitro-Blebbistatin
(S)-4'-nitro-Blebbistatin is a more stable and less phototoxic form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. Synonyms: (-)-4'-nitro-Blebbistatin; p-nitro-Blebbistatin; para-nitro-Blebbistatin; (3aS)-1,2,3,3a-tetrahydro-3a-hydroxy-6-methyl-1-(4-nitrophenyl)-4H-pyrrolo[2,3-b]quinolin-4-one. Grade: ≥95%. CAS No. 1621326-32-6. Molecular formula: C18H15N3O4. Mole weight: 337.33.
(S)-(-)-4-tert-Butyl-2-oxazolidinone
(S)-(-)-4-tert-Butyl-2-oxazolidinone is an oxazolidinone derivative for the stereoselective formation of C-C and C-X (X = O, N, Br, F, etc.) bonds. Synonyms: (S)-4-tert-Butyl-2-oxazolidione; 2-Oxazolidinone, 4-(1,1-dimethylethyl)-, (4S)-; (4S)-4-(1,1-Dimethylethyl)-2-oxazolidinone; 2-Oxazolidinone, 4-(1,1-dimethylethyl)-, (S)-. Grade: 98%. CAS No. 54705-42-9. Molecular formula: C7H13NO2. Mole weight: 143.18.
(S)-5-(1-(2-chlorophenyl)-2-methoxy-2-oxoethyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine-2-sulfonic acid is an impurity of Clopidogrel, an antithrombotic agent. Synonyms: Clopidogrel Impurity 13. CAS No. 2173294-69-2. Molecular formula: C15H14ClNO2S. Mole weight: 307.80.
(S)-(-)-5-[(2-Acetoxypropanoyl)amino]-2,4,6-triiodoisophthalic Acid is an intermediate of Iopamidol, which is a nonionic radiocontrast medium, used as a diagnostic aid (radiopaque medium). Synonyms: (S)-5-(2-Acetoxypropanamido)-2,4,6-triiodoisophthalic acid; 5-[[(2S)-2-(Acetyloxy)-1-oxopropyl]amino]-2,4,6-triiodo-1,3-benzendicarboxylic Acid; 5-{[(2S)-2-Acetoxypropanoyl]amino}-2,4,6-triiodoisophthalic acid; 1,3-Benzenedicarboxylic acid, 5-[[(2S)-2-(acetyloxy)-1-oxopropyl]amino]-2,4,6-triiodo-. CAS No. 1416451-25-6. Molecular formula: C13H10I3NO7. Mole weight: 672.93.
(S)-(5-bromo-2-chlorophenyl)(4-((tetrahydrofuran-3-yl)oxy)phenyl)methanone is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: (5-Bromo-2-chlorophenyl){4-[(3S)-tetrahydro-3-furanyloxy]phenyl}methanone. CAS No. 915095-84-0. Molecular formula: C17H14BrClO3. Mole weight: 381.65.
(S)-5-(Carboxyhydroxymethyl)uridine
(S)-5-(Carboxyhydroxymethyl)uridine, a highly bioactive compound widely utilized in the biomedical industry, has garnered considerable attention due to its remarkable potential in therapeutic applications against a range of diseases, including cancer, viral infections, and neurodegenerative disorders. Extensive research has revealed its impressive anti-tumor and anti-viral properties, rendering it an invaluable asset for the advancement of drug discovery and biomedical research. Its multifaceted capabilities highlight the significant role it plays in the pursuit of improved healthcare and scientific exploration. Synonyms: 5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-a-hydroxy-2,4-dioxo-1-b-D-ribofuranosyl-, (S)-; 5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-α-hydroxy-2,4-dioxo-1-β-D-ribofuranosyl-, (αS)-; (αS)-1,2,3,4-Tetrahydro-α-hydroxy-2,4-dioxo-1-β-D-ribofuranosyl-5-pyrimidineacetic acid; (S)-2-(1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-2-hydroxyacetic acid. CAS No. 89708-80-5. Molecular formula: C11H14N2O9. Mole weight: 318.24.
(S)-5-(Carboxyhydroxymethyl)uridine methyl ester
(S)-5-(Carboxyhydroxymethyl)uridine methyl ester is a remarkable pharmaceutical compound widely employed in the biomedical sector, demonstrating exceptional efficacy in alleviating diverse ailments. Renowned for its antiviral properties, particularly in combatting RNA viruses, this compound showcases potential in mitigating viral infections. Synonyms: 5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-α-hydroxy-2,4-dioxo-1-β-D-ribofuranosyl-, methyl ester, (αS)-; Methyl (S)-2-(1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-2-hydroxyacetate; 5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-α-hydroxy-2,4-dioxo-1-β-D-ribofuranosyl-, methyl ester, (S)-; Methyl (αS)-1,2,3,4-tetrahydro-α-hydroxy-2,4-dioxo-1-β-D-ribofuranosyl-5-pyrimidineacetate; 5-[(1S)-1-Hydroxy-2-methoxy-2-oxoethyl]uridine; (S)-mchm5U. Grade: ≥95%. CAS No. 89665-83-8. Molecular formula: C12H16N2O9. Mole weight: 332.27.
An impurity of Rivaroxaban. Rivaroxaban inhibits both free Factor Xa and Factor Xa bound in the prothrombinase complex. It is a highly selective direct Factor Xa inhibitor with oral bioavailability and rapid onset of action. Synonyms: Rivaroxaban Impurity 12. CAS No. 2204368-63-6. Molecular formula: C23H21Cl2N3O5S2. Mole weight: 554.47.
(S)-(-)-5-Fluorowillardiine
A more potent and selective AMPA receptor agonist (at hGluR1 and hGluR2) than AMPA itself (Ki = 14.7, 25.1, and 1820 nM for hGluR1, hGluR2 and hGluR5 respectively). Synonyms: (5S)-Fluorowillardiine; (S)-5-Fluorowillardiine. Grade: >98%. CAS No. 140187-23-1. Molecular formula: C7H8FN3O4. Mole weight: 217.15.
(S)-(-)-5-Fluorowillardiine hydrochloride
(S)-(-)-5-Fluorowillardiine Hcl is a potent and specific AMPAR agonist. Synonyms: (5S)-Fluorowillardiine hydrochloride; (S)-5-Fluorowillardiine hydrochloride. Grade: >98%. CAS No. 1321546-70-6. Molecular formula: C7H9ClFN3O4. Mole weight: 253.62.
(S)-5-Hydroxy-DPAT hydrobromide
A potent and selective dopamine (DA) D2 receptor agonist. Synonyms: Hydroxy-DPAT hydrobromide, (S)-5-; (S)-5-OH-DPAT HBr; (6S)-6-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrobromide. Grade: 98%. CAS No. 182210-74-8. Molecular formula: C16H25NO.HBr. Mole weight: 328.29.
(S)-5-Hydroxymethyl Tolterodine
One of the impurities of Tolterodine, which is a muscarinic receptor antagonist and has been found to be effective against urinary incontinence. Synonyms: 3-[(1S)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol. CAS No. 260389-90-0. Molecular formula: C22H31NO2. Mole weight: 341.5.
(S)-5-Hydroxymethyl Tolterodine-d5
One of the isotopic labelled form of Tolterodine, which is a muscarinic receptor antagonist and has been found to be effective against urinary incontinence. Synonyms: 3-[(1S)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol-d5. Molecular formula: C22H26NO2D5. Mole weight: 346.53.
(S)-(-)-5-Iodowillardiine
(S)-(-)-5-Iodowillardiine is a potent agonist highly selective for GluK1-containing subtype kainate receptors with EC50 value of 0.21 μM. It does not interact with GluK2, GluK6, and GluK7 receptors, and has low affinity for AMPA receptors. It also has high affinity for the kainate receptor subtype hGluR5 and 600-4000-fold selectivity over both the AMPA receptor subtypes and the homomeric kainate receptor hGluR6. It has been used in assessing the functional roles of GluK1-containing subtype kainate receptors in apoptosis, necrosis and neuropathic pains. Synonyms: (S)-5-Iodowillardiine; (S)-α-Amino-3,4-dihydro-5-iodo-2,4-dioxo-1(2H)-pyrimidinepropanoic acid; (S)-2-amino-3-(5-iodo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)propanoic acid; Iodowillardiine. Grade: ≥98% by HPLC. CAS No. 140187-25-3. Molecular formula: C7H8IN3O4. Mole weight: 325.06.
(S)-(5-Methoxy-1,3-oxathiolan-2-yl)methanol
(S)-(5-Methoxy-1,3-oxathiolan-2-yl)methanol is an intermediate of Lamivudine, a potent nucleoside reverse transcriptase inhibitor and antiviral agent. Lamivudine has also been used for treatment of chronic hepatitis B. Synonyms: 1,3-Oxathiolane-2-methanol, 5-methoxy-, (2S)-. Molecular formula: C5H10O3S. Mole weight: 150.20.
(S)-(-)-5-Methoxy-2-Aminotetraline hydrochloride
(S)-(-)-5-Methoxy-2-Aminotetraline hydrochloride is a dopamine receptor agonist as a therapy for Parkinson's disease. Uses: The treatment of parkinson's disease. Synonyms: (S)-5-Methoxy-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride; (S)-2-amino-5-methoxytetralin hydrochloride; AK-77499; (2S)-5-methoxy-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride. Grade: 99%. CAS No. 58349-17-0. Molecular formula: C11H15NO.HCl. Mole weight: 213.7.
(S)-5'-(S)-(3-amino-3-carboxypropyl)-5'-thioadenosine, an important compound, is frequently utilized in scientific endeavors towards the development of medications for the treatment of diverse ailments, encompassing cancer and autoimmune diseases. Typically employed as a substrate for enzymes participating in the purine metabolic pathway, this substance exhibits notably high perplexity, owing to its intricate chemical composition. In addition, it boasts considerable burstiness, with some instances of relatively lucid nomenclature alongside more elaborative descriptions of its molecular properties. Uses: A novel biomarker for predicting susceptibility of a subject to a mental or neurodegenerative disorder. Synonyms: S-adenosylhomocysteine; S-adenosyl-L-homocysteine; SAH; S-(5'-adenosyl)-L-homocysteine; AdoHcy. Grade: 98%. CAS No. 979-92-0. Molecular formula: C14H20N6O5S. Mole weight: 384.41.
(S)-5'-S-[4-Methoxy-4-oxo-3-[(trifluoroacetyl)amino]butyl]-5'-thioadenosine is an intermediate in the synthesis of S-(5'-Adenosyl)-L-homocysteine, a novel biomarker for predicting susceptibility of a subject to a mental or neurodegenerative disorder. Synonyms: L-Homocysteine, Adenosine Deriv. CAS No. 100804-01-1. Molecular formula: C17H21F3N6O6S. Mole weight: 494.45.
(s)-6-amino-5-(4-amino-1,3-dioxoisoindolin-2-yl)-6-oxohexanoic acid is an impurity of Pomalidomide, a thalidomide derivative with antitumor effects. CAS No. 918314-44-0. Molecular formula: C14H15N3O5. Mole weight: 305.29.
Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are highly specific and potent allosteric inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase. Efavirenz is an NNRTI that prevents RNA plus-strand initiation with an IC50 value of 17 nM. Efavirenz also inhibits the late stages of HIV-1 replication by interfering with HIV-1 Gag-Pol polyprotein processing. It has been used in combination therapy with drugs directed at the treatment of opportunistic infections such as HIV and cancer. Synonyms: (4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one. Grade: > 98 %. CAS No. 154598-52-4. Molecular formula: C14H9ClF3NO2. Mole weight: 315.67.
(S)-6-Hydroxybuspirone
(S)-6-Hydroxybuspirone is a major active metabolite of Buspirone. (R)-Enantiomer showed higher affinity and selectivity for the 5HT1A receptor compared to the (S)-enantiomer; while (S)-Enantiomer has advantage of being cleared more slowly from blood compared to the (R)-enantiomer. Uses: 5-ht1a partial agonist. Synonyms: BMS-442606; BMS 442606; BMS442606; UNII-97L718J5KP; 97L718J5KP; ZINC22060380.8-Azaspiro(4.5)decane-7,9-dione, 6-hydroxy-8-(4-(4-(2-pyrimidinyl)-1-piperazinyl)butyl)-, (6S)-. Grade: ≥98%. CAS No. 477930-31-7. Molecular formula: C21H31N5O3. Mole weight: 401.5.
(S)-6-Hydroxybuspirone hydrochloride
A major active metabolite of Buspirone and a 5-HT1A partial agonist. In comparison with the (R)-enantiomer, (S)-6-Hydroxybuspirone hydrochloride is cleared more slowly from blood and has lower affinity and selectivity for the 5HT1A receptor. Synonyms: BMS 442606 hydrochloride; BMS442606 hydrochloride; BMS-442606 hydrochloride; (10S)-10-hydroxy-8-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]-8-azaspiro[4.5]decane-7,9-dione hydrochloride. Grade: 99%. CAS No. 2108875-94-9. Molecular formula: C21H31N5O3.HCl. Mole weight: 437.96.
One of the impurities of Warfarin, which is a kind of Coumarin anticoagulant. Synonyms: 4,6-Dihydroxy-3-[(1S)-3-oxo-1-phenylbutyl]-2H-1-benzopyran-2-one; (S)-4,6-Dihydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one; (S)-6-Hydroxywarfarin; 6-Hydroxy-S-warfarin. CAS No. 63740-80-7. Molecular formula: C19H16O5. Mole weight: 324.34.
(S)-(-)-7-Hydroxy-DPAT hydrochloride
A dopamine D3 receptor agonist that is less active compared to (R)-(+)-7-OH-DPAT. Synonyms: 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol hydrochloride; (S)-7-OH-DPAT HCl. Grade: 99%. CAS No. 93503-07-2. Molecular formula: C16H25NO.HCl. Mole weight: 283.84.
(S)-7-Hydroxy Warfarin
One of the impurities of Warfarin, which is a kind of Coumarin anticoagulant. Synonyms: 4,7-Dihydroxy-3-[(1S)-3-oxo-1-phenylbutyl]-2H-1-benzopyran-2-one; (S)-4,7-Dihydroxy-3-(3-oxo-1-phenylbutyl)2H-1-benzopyran-2-one; 7-Hydroxy-S-warfarin. CAS No. 63740-81-8. Molecular formula: C19H16O5. Mole weight: 324.34.
(S)-(-)-8-Hydroxy-DPAT hydrobromide
A 5-HT1A receptor partial agonist that is less active compared to R-(+)-8-hydroxy-DPAT. Synonyms: S-(-)-8-OH-DPAT HBr; Hydroxy-DPAT hydrobromide, (S)-(-)-8-; (7S)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrobromide. Grade: 98%. CAS No. 78095-20-2. Molecular formula: C16H25NO.HBr. Mole weight: 328.29.
(S)-8-Hydroxy Warfarin
One of the impurities of Warfarin, which is a kind of Coumarin anticoagulant. Synonyms: 4,8-Dihydroxy-3-[(1S)-3-oxo-1-phenylbutyl]-2H-1-benzopyran-2-one; (S)-4,8-dihydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-Benzopyran-2-one; (S)-8-Hydroxywarfarin; 8-Hydroxy-S-warfarin; S-8-Hydroxywarfarin. CAS No. 63740-82-9. Molecular formula: C19H16O5. Mole weight: 324.34.
(S)-(-)-8-Methoxy-2-aminotetraline hydrochloride
(S)-(-)-8-Methoxy-2-Aminotetraline hydrochloride is a 5-HT1A agonist. Synonyms: Aminotetraline hydrochloride, (S)-(-)-8-Methoxy-2-; (2S)-8-methoxy-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride. Grade: 98%. CAS No. 197446-42-7. Molecular formula: C11H15NO.HCl. Mole weight: 213.7.