BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Sp-6-Phe-cAMPS | Sp-6-Phe-cAMPS is a selective and PDE-resistant stimulator of protein kinase A, which is used as an Epac-negative control. Grades: ≥ 98% by HPLC. CAS No. 169335-92-6. Molecular formula: C16H15N5O5PS · Na. Mole weight: 443.4. |  |
| Sp-8-AEA-cAMPS | Sp-8-AEA-cAMPS is a phosphodiesterase-resistant ligand for affinity chromatography of cAMP and cGMP binding proteins. It is often modified with fluorophores and other markers. Synonyms: 8- (2- Aminoethylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer. Grades: ≥ 98% by HPLC. CAS No. 221904-84-3. Molecular formula: C12H18N7O5PS. Mole weight: 403.4. | |
| Sp-8-AHA-cAMPS | Sp-8-AHA-cAMPS is a PDE-stable cAMP analogue used for immobilization as an affinity ligand or for coupling of labelling structures such as fluorophores. It is also a PDE-resistant analogue of 8-AHA-cAMP. Synonyms: 8- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer. Grades: ≥ 98% by HPLC. CAS No. 214272-03-4. Molecular formula: C16H26N7O5PS. Mole weight: 459.5. | |
| Sp-8-Br-2'-O-Me-cAMPS | Sp-8-Br-2'-O-Me-cAMPS is a anti-hydrolytic form of 8-Br-2'-O-Me-cAMP, a specific membrane-permeant stimulator of the exchange protein activated by cAMP (Epac) or cAMP-GEF. Synonyms: 8- Bromo- 2'- O- methyladenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 634208-34-7. Molecular formula: C11H12BrN5O5PS · Na. Mole weight: 460.2. | |
| Sp-8-Br-cGMPS | Sp-8-Br-cGMPS is an activator of protein kinase G I α and protein kinase A. It has a resistant effect against cyclic nucleotide phosphodiesterases. Compared to cGMP or Sp-cGMPS, it has more lipophilic and membrane-permeant properties. Synonyms: 8- Bromoguanosine- 3', 5'- monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 153660-03-8. Molecular formula: C10H10BrN5O6PS · Na. Mole weight: 462.2. | |
| Sp-8-Br-PET-cGMPS | Sp-8-Br-PET-cGMPS is an inhibitor of the retinal type cGMP-gated ion channel (cGMP antagonist) as well as a stimulator of cyclic GMP-dependent protein kinase I α and I ß (cGMP agonist), which is used for distinction between kinase and ion channel mediated effects. It effects against mammalian cyclic nucleotide-dependent phosphodiesterases. Synonyms: 8- Bromo- β- phenyl- 1, N2- ethenoguanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 172806-21-2. Molecular formula: C18H14BrN5O6PS · Na. Mole weight: 562.3. | |
| Sp-8-Cl-cAMPS | Sp-8-Cl-cAMPS is a resistant stimulator of protein kinase A, the cAMP agonist. Compared with 8-Cl-cAMP, it has the increased lipophilic and membrane-permeant properties. Synonyms: 8- Chloroadenosine- 3', 5'- monophosphorothioate, Sp- isomer. Grades: ≥ 99% by HPLC. CAS No. 142754-28-7. Molecular formula: C10H10ClN5O5PS · Na. Mole weight: 401.7. | |
| Sp-8-CPT-cAMPS | Sp-8-CPT-cAMPS is a selective activator of protein kinase A (cAMP agonist). It effects against mammalian cyclic nucleotide-dependent phosphodiesterases. Synonyms: 8- (4- Chlorophenylthio)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 129693-13-6. Molecular formula: C16H14ClN5O5PS2 · Na. Mole weight: 509.8. | |
| Sp-8-OH-cAMPS | Sp-8-OH-cAMPS is a polar analogue of Sp-cAMPS, the protein kinase A activator, with an antagonistic effect of mammalian cyclic nucleotide-dependent phosphodiesterases. It can be used for the study of extracellular cAMP receptors. Synonyms: 8- Hydroxyadenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 749843-87-6. Molecular formula: C10H11N5O6PS · Na. Mole weight: 383.3. | |
| Sp-8-pCPT-2'-O-Me-cAMPS | Sp-8-pCPT-2'-O-Me-cAMPS is an activator of the exchange protein activated by cAMP (Epac) or cAMP-GEF, which is inactive for protein kinase A. It is much more lipophilic and membrane permeant. Synonyms: 8- (4- Chlorophenylthio)- 2'- O- methyladenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 634208-37-0. Molecular formula: C17H16ClN5O5PS2 · Na. Mole weight: 523.9. | |
| Spadin | Spadin is a potent and brain penetrating TREK-1 channel blocker (IC50 = 71 nM) displaying antidepressant activity. Spadin enhances dorsal raphe nucleus 5-HT neurotransmission in mice and induces hippocampal CREB activation and neurogenesis in adult mice. Synonyms: Spadin; 1270083-24-3; Spadin (trifluoroacetate salt); HB5438; AKOS025293510; C96H142N26O22; S-1270083-24-3. CAS No. 1270083-24-3. Molecular formula: C96H142N26O22. Mole weight: 2012.34. | |
| Spaglumic Acid | Spaglumic Acid is a peptide neurotransmitter and the third-most-prevalent neurotransmitter in the mammalian nervous system. NAAG consists of N-acetylaspartic acid and glutamic acid coupled via a peptide bond. Spaglumic Acid alsp acts as an NMDA receptor activator and mGlu3 receptor agonist. Synonyms: N-Acetyl-L-aspartyl-L-glutamic acid; Isospaglumic acid; NAAG; N-Acetyl-Asp-Glu; N-acetylaspartylglutamate. Grades: ≥96% by HPLC. CAS No. 3106-85-2. Molecular formula: C11H16N2O8. Mole weight: 304.26. | |
| Sp-cAMPS-AM | Sp-cAMPS-AM is a precursor of Sp-cAMPS, the PDE-resistant protein kinase A stimulator. Sp-cAMPS is released after metabolism of Sp-cAMPS-AM by esterases. Synonyms: Adenosine- 3', 5'- monophosphorothioate acetoxymethyl ester, Sp- isomer. Grades: ≥ 97% by HPLC for mixture of the axial and equatorial isomer. CAS No. 152218-24-1. Molecular formula: C13H16N5O7PS. Mole weight: 417.3. | |
| Sp-cAMPS, sodium salt | Sp-cAMPS is an activator of protein kinase A (cAMP agonist). It exhibits high resistance against cyclic nucleotide phosphodiesterases and membrane permeability in organisms. Uses: Protein kinase inhibitors. Synonyms: Adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 71774-13-5. Molecular formula: C10H11N5O5PS · Na. Mole weight: 367.3. | |
| Sp-cAMPS, triethyl ammonium salt | Sp-cAMPS is a stimulator of protein kinase A, the cAMP agonist. It has higher resistance against cyclic nucleotide phosphodiesterases compared to dibutyryl- or 8-Br-cAMP and membrane permeability comparable to 8-Br-cAMP. Synonyms: Adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, triethyl ammonium salt. Grades: ≥ 98% by HPLC. CAS No. 93602-66-5. Molecular formula: C10H11N5O5PS · C6H16N. Mole weight: 446.5. | |
| Sp-cCMPS | Sp-cCMPS is a PDE-resistant cCMP, the potential second messenger, which may activate cCMP-binding proteins. Synonyms: Cytidine- 3', 5'- cyclic monophosphorothioate, Sp- isomer. Grades: ≥ 98% by HPLC. CAS No. 87063-81-8. Molecular formula: C9H11N3O6PS · Na. Mole weight: 343.2. | |
| Sp-dUTP-α-S | Sp-dUTP-α-S is an intriguing and invaluable nucleotide analog meticulously designed for elucidating the intricacies of molecular biology endeavors, unveiling its indispensable presence in the realm of DNA sequencing, polymerase chain reaction (PCR) and DNA labeling. Synonyms: 2'- Deoxyuridine- 5'- O- (1- thiotriphosphate), Sp-isomer. Grades: ≥ 95% by HPLC. CAS No. 876068-87-0. Molecular formula: C9H11N2O13P3S (free acid). Mole weight: 484.2 (free acid). | |
| Speract | Speract, a peptide associated with eggs of sea urchin, Lytechinus pictus, regulates sperm motility, also stimulates sperm mitochondrial metabolism. Synonyms: H-Gly-Phe-Asp-Leu-Asn-Gly-Gly-Gly-Val-Gly-OH; glycyl-L-phenylalanyl-L-alpha-aspartyl-L-leucyl-L-asparagyl-glycyl-glycyl-glycyl-L-valyl-glycine. CAS No. 76901-59-2. Molecular formula: C38H57N11O14. Mole weight: 891.92. | |
| Spermine Phosphoramidite | Spermine Phosphoramidite, a crucial component in synthesizing spermine-modified oligonucleotides, serves as a prime candidate for delving into DNA-protein interactions and cancer cell targeting, rendering itself a shining star in biomedical research. Uncovering new therapeutic avenues for neurodegenerative diseases and cancer is the cherry on top of this innovative product. Synonyms: N-[4-(4,4'-Dimethoxytrityloxy)butyl]-N,N4,N9,N-tetrakis(trifluoroacetyl)-spermine-N-butyl-4-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C56H73F12N6O9P. Mole weight: 1233.17. | |
| Sperm surface protein Sp17 (103-111) | Sperm surface protein Sp17 (103-111) is a truncated fragment of Sperm surface protein Sp17. Sperm surface protein Sp17 is a sperm surface zona pellucida binding protein which helps to bind spermatozoa to the zona pellucida with high affinity. Synonyms: Cancer/testis antigen 22 (103-111); Sp17-1 (103-111); Sperm autoantigenic protein 17 (103-111). | |
| Sp-GDP-α-S | Sp-GDP-α-S is a GDP binding proteins regulator with high stability, which is used for characterization of GDP-responsive receptors and determination of their stereospecificity. Synonyms: Guanosine- 5'- O- (1- thiodiphosphate), Sp- isomer, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 71481-45-3. Molecular formula: C10H15N5O10P2S (free acid). Mole weight: 459.3 (free acid). | |
| Spinorphin | Spinorphin is an endogenous neuropeptide that inhibits enkephalin-degrading enzymes (aminopeptidase, dipeptidyl aminopeptidase III, neprilysin) and angiotensin-converting enzyme. Spinorphin exhibits antinociceptive effects in mice. Synonyms: L-Threonine, N-(N-(1-(N-(N-(N-L-leucyl-L-valyl)-L-valyl)-L-tyrosyl)-L-prolyl)-L-tryptophyl)-. CAS No. 137201-62-8. Molecular formula: C45H64N8O10. Mole weight: 877.03. | |
| Splenopentin diacetate | Splenopentin diacetate is a synthetic immunomodulating peptide corresponding to the region 32-34 of a splenic product called splenin (SP) and the thymic hormone thymopoietin (TP) respectively. It can reproduce the biological activities of TP and SP respectively. Uses: Splenopentin diacetate can reproduce the biological activities of tp and sp respectively. Synonyms: Splenopentin Acetate; SP-5; Splenin pentapeptide (32-36); Thymopoietin III pentapeptide (32-36). Grades: >98%. CAS No. 105184-37-0. Molecular formula: C35H59N9O13. Mole weight: 813.90. | |
| (S)-(-)-Propranolol hydrochloride | The S-enantiomer of Propranolol.Propranolol is Beta 1 adrenergic receptor antagonist. It can be used for the treatment of high blood pressure, a number of types of irregular heart rate, thyrotoxicosis, capillary hemangiomas, performance anxiety, and essential tremors. Synonyms: (S)-1-Isopropylamino-3-(1-naphthyloxy)-2-propanol hydrochloride. Grades: ≥ 95% (NMR). CAS No. 4199-10-4. Molecular formula: C16H22ClNO2. Mole weight: 295.8. | |
| Sp-TTP-α-S | Sp-TTP-α-S is used for regulation of TTP-responsive receptors and determination of their stereospecificity. Compared to TTP, it is much more stable. Uses: Antiviral agents. Synonyms: Thymidine- 5'- O- (1-thiotriphosphate), Sp-isomer. Grades: ≥ 95% by HPLC. CAS No. 83199-32-0. Molecular formula: C10H17N2O13P3S (free acid). Mole weight: 498.2 (free acid). | |
| SSA protein SS-56 (55-64) | A peptide fragment of SSA protein SS-56. | |
| ß-L-LNA-G(iBu) Phosphoramidite | | |
| S-Sulfo-L-cysteine Sodium Salt | S-Sulfo-L-cysteine sodium salt is an EAA receptor agonist. It is also reported to be an agonist at mGlu1α and mGlu5a subtypes expressed in clonal RGT cell lines. Synonyms: L-Cysteine, Hydrogen Sulfate (Ester), Monosodium Salt (6CI,8CI); L-Cysteine, Hydrogen Sulfate (Ester), Monosodium Salt (9CI); NSC 344479; S-Sulfocysteine Monosodium Salt; S-Sulfocysteine Sodium Salt; Sodium Cysteine-S-sulfonate. Grades: 85%. CAS No. 7381-67-1. Molecular formula: C3H6NNaO5S2. Mole weight: 223.20. | |
| S Tag Peptide | S Tag Peptide, a 15 amino acid peptide derived from RNase A, is an oligopeptide used for improving protein solubility. Synonyms: Lys-Glu-Thr-Ala-Ala-Ala-Lys-Phe-Glu-Arg-Gln-His-Met-Asp-Ser; L-lysyl-L-alpha-glutamyl-(3xi)-L-threonyl-L-alanyl-L-alanyl-L-alanyl-L-lysyl-L-phenylalanyl-L-alpha-glutamyl-L-arginyl-L-glutaminyl-L-histidyl-L-methionyl-L-alpha-aspartyl-L-serine; S Tag. Grades: ≥95%. Molecular formula: C73H117N23O25S. Mole weight: 1748.91. | |
| Stavudine 5'-monophosphate sodium salt | Stavudine 5'-monophosphate sodium salt is an indispensable pharmaceutical compound in the research of HIV/AIDS, acting as a nucleoside reverse transcriptase inhibitor. Through intricate interference with the genetic material of the virus, it effectively obstructs viral replication. Synonyms: 2',3'-Didehydro-2',3'-dideoxythymidine-5'-monophosphate sodium salt. Molecular formula: C10H13N2O7P·xNa. Mole weight: 304.19 (free acid). | |
| Stavudine 5'-triphosphate sodium salt | Stavudine 5'-triphosphate sodium salt is a paramount constituent within the biomedical sector, aiding in studying viral infections instigated by the human immunodeficiency virus (HIV). Serving as an antiretroviral compound, it effectively hampers the HIV reverse transcriptase enzyme and thwarts viral reproduction. Synonyms: 2',3'-Didehydro-2',3'-dideoxy-thymidine-5'-triphosphate sodium salt. Molecular formula: C10H15N2O13P3·xNa. Mole weight: 464.15 (free acid). | |
| Stavudine 5'-triphosphate triethyammonium salt | Stavudine 5'-triphosphate triethyammonium salt is a vital bioactive constituent adopted within the research of human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS). By virtue of its potent action in disabling the reverse transcriptase enzyme associated with HIV, this invaluable compound imparts a noteworthy hampering effect on the viral replication process. Synonyms: 2',3'-Didehydro-2'-3'-dideoxythymidine 5'-triphosphate sodium salt. | |
| Stearyl Phosphoramidite | Stearyl Phosphoramidite, a pivotal chemical compound in oligonucleotide synthesis, has a reputation for stability and compatibility with everyday solvents. A must-have reagent in the production of nucleic acid derivatives, Stearyl Phosphoramidite is essential in targeted cancer therapies and genetic disease treatments with the added benefit of enhancing drug pharmacokinetics and biocompatibility. Synonyms: Octadecyl-1-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C27H55N2O2P. Mole weight: 470.71. | |
| STh | STh is a heat stable toxin of Escherichia coli. CAS No. 118447-40-8. Molecular formula: C79H112N22O30S6. Mole weight: 2042.25. | |
| St-Ht31 P | Negative control for st-Ht31. Synonyms: stearoyl-Asp-Leu-Ile-Glu-Glu-Ala-Ala-Ser-Arg-Pro-Val-Asp-Ala-Val-Pro-Glu-Gln-Val-Lys-Ala-Ala-Gly-Ala-Tyr-OH; N-stearoyl-L-alpha-aspartyl-L-leucyl-L-isoleucyl-L-alpha-glutamyl-L-alpha-glutamyl-L-alanyl-L-alanyl-L-seryl-L-arginyl-L-prolyl-L-valyl-L-alpha-aspartyl-L-alanyl-L-valyl-L-prolyl-L-alpha-glutamyl-L-glutaminyl-L-valyl-L-lysyl-L-alanyl-L-alanyl-glycyl-L-alanyl-L-tyrosine. Grades: >98%. CAS No. 252869-81-1. Molecular formula: C127H209N29O39. Mole weight: 2766.19. | |
| S-Trityl-L-cysteine | S-Trityl-L-cysteine is a cell-permeable, potent and selective inhibitor of mitotic kinesin Eg5, a protein required for establishing and maintaining a bipolar spindle. S-Trityl-L-cysteine inhibits basal and microtubule-activated ATPase activity of Eg5 (IC50 = 1 mM and 140 nM, respectively). S-Trityl-L-cysteine was shown to induce mitotic arrest in HeLa cells with an IC50 of 700 nM. Synonyms: S-(Triphenylmethyl)-L-cysteine. Grades: ≥ 98% (HPLC). CAS No. 2799-7-7. Molecular formula: C22H21NO2S. Mole weight: 363.47. | |
| Structure-specific endonuclease subunit SLX4 (603-615) | Structure-specific endonuclease subunit SLX4 (603-615) is a 13-aa peptide. SLX4 is required for recovery from alkylation-induced DNA damage and is involved in the resolution of DNA double-strand breaks. Synonyms: BTB/POZ domain-containing protein 12 (603-615). | |
| Substance P | Substance P, a neuropeptide, is a sensory neuropeptide and inflammatory mediator. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor,NK1R). Synonyms: Substance P Acetate. CAS No. 33507-63-0. Molecular formula: C63H98N18O13S. Mole weight: 1347.63. | |
| Suc-Ala-Ala-pNA | Synonyms: Succinyl-L-alanyl-L-alanine p-nitroanilide; Succinyl-alanyl-alanine-4-nitroanilide. CAS No. 61043-66-1. Molecular formula: C16H20N4O7. Mole weight: 380.36. | |
| Succinimidyl 4-(4-azidophenyl)butyrate | Synonyms: SAPB. Grades: ≥ 99% (NMR). CAS No. 441052-82-0. Molecular formula: C14H14N4O4. Mole weight: 302.29. | |
| Succinoadenosine 1,2-Dibenzyl Ester | Succinoadenosine 1,2-Dibenzyl Ester, an intermediate in the synthesis of Succinoadenosine, which is a biochemical marker of adenylosuccinase deficiency-the genetic defect of purine de novo synthesis. Molecular formula: C28H29N5O8. Mole weight: 563.56. | |
| Surface IgG (sA20-Ig) of A20 (106-114) | Surface IgG (sA20-Ig) of A20 (106-114) is a peptide corresponding to residues 106-114 of Surface IgG (sA20-Ig) of A20. Inoculation of the Id-peptide in A20-engrafted mice caused apoptosis of tumor cells and resulted in tumor growth inhibition and extended survival of diseased animals. Synonyms: Surface IgG (sA20-Ig) of A20 B-lymphoma cell line (106-114). | |
| Survivin (18-27) | A peptide fragment of Survivin. Survivin, also called BIRC5 , is a member of the apoptosis inhibitor protein family containing a baculovirus domain. Survivin is overexpressed in most human cancers but rarely expressed in normal differentiated adult tissues. Synonyms: Survivin (18-27)(modK); Sur18K10; Baculoviral IAP repeat-containing protein 5 (18-27). | |
| Survivin-3A (96-104) | Survivin-3A (96-104) is a 9-aa peptide. Survivin is the smallest member of the Inhibitor of apoptosis (IAP) family of proteins, involved in inhibition of apoptosis and regulation of cell cycle. | |
| Survivin (80-88) | A peptide fragment of Survivin. Survivin, also called BIRC5 , is a member of the apoptosis inhibitor protein family containing a baculovirus domain. Survivin is overexpressed in most human cancers but rarely expressed in normal differentiated adult tissues. Synonyms: Baculoviral IAP repeat-containing protein 5 (80-88). | |
| SV40 large T antigen NLS | SV40 large T antigen NLS, a hexamer protein generated from Large T antigen residue 47 to 55, enables protein import into cell nucleus. Synonyms: Cys-Gly-Gly-Gly-Pro-Lys-Lys-Lys-Arg-Lys-Val-Glu-Asp. Grades: ≥95%. Molecular formula: C58H104N20O18S. Mole weight: 1401.63. | |
| Symmetric Doubler Phosphoramidite | Symmetric Doubler Phosphoramidite is a reagent widely used in solid-phase synthesis for the preparation of double-stranded DNA and RNA molecules for biomedical research. It plays a vital role as a coupling agent in the creation of oligonucleotides for gene sequencing and gene therapy, as well as in the development of new drugs for the treatment of various diseases. Synonyms: 1, 3-bis-[5- (4, 4'-dimethoxytrityloxy) pentylamido]propyl-2-[ (2-cyanoethyl) - (N, N-diisopropyl) ]-phosphoramidite; N,N'-[2-[[(Diisopropylamino)2-cyanoethoxyphosphino]oxy]-1,3-propanediyl]bis[5-[(4,4'-dimethoxytrityl)oxy]pentanamide]. Molecular formula: C64H79N4O10P. Mole weight: 1095.32. | |
| Syntide 2 | Syntide 2, a synthetic peptide, is recognized as a substrate by Ca2+/calmodulin-dependent protein kinase II (CaMKII) (Ki= 12 μM) and protein kinase C (Km = 11 μM). Synonyms: Calmodulin-Dependent Protein Kinase Substrate; Pro-Leu-Ala-Arg-Thr-Leu-Ser-Val-Ala-Gly-Leu-Pro-Gly-Lys-Lys; L-prolyl-L-leucyl-L-alanyl-L-arginyl-L-threonyl-L-leucyl-L-seryl-L-valyl-L-alanyl-glycyl-L-leucyl-L-prolyl-glycyl-L-lysyl-L-lysine; Syntide-2; Syntide2. Grades: ≥97% by HPLC. CAS No. 108334-68-5. Molecular formula: C68H122N20O18. Mole weight: 1507.82. | |
| SYSMEHFRWGKPS | SYSMEHFRWGKPS is a peptide containing 13 amino acids. Synonyms: Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Ser. Grades: ≥95%. Molecular formula: C73H102N20O20S. Mole weight: 1611.81. | |
| Systemin | Systemin, an 18-amino acid peptide isolated from tomato leaves, is a powerful inducer of more than 15 defense genes. Synonyms: Ala-Val-Gln-Ser-Lys-Pro-Pro-Ser-Lys-Arg-Asp-Pro-Pro-Lys-Met-Gln-Thr-Asp; L-alanyl-L-valyl-L-glutaminyl-L-seryl-L-lysyl-L-prolyl-L-prolyl-L-seryl-L-lysyl-L-arginyl-L-alpha-aspartyl-L-prolyl-L-prolyl-L-lysyl-L-methionyl-L-glutaminyl-L-threonyl-L-aspartic acid. Grades: ≥95% by HPLC. CAS No. 137181-56-7. Molecular formula: C85H144N26O28S. Mole weight: 2010.28. | |
| SYT-SSX1 or -SSX2 fusion protein (402-410 (SYT)) | | |
| T7 Tag Peptide | T7 Tag Peptide, an epitope tag composed of an 11-residue peptide encoded from the leader sequence of the T7 bacteriophage gene10, and serves as a tag in many expression vectors that is based on the very efficient T7 RNA polymerase expression system. Synonyms: Met-Ala-Ser-Met-Thr-Gly-Gly-Gln-Gln-Met-Gly; L-methionyl-L-alanyl-L-seryl-L-methionyl-(3xi)-L-threonyl-glycyl-glycyl-L-glutaminyl-L-glutaminyl-L-methionyl-glycine. Grades: ≥95%. Molecular formula: C41H71N13O16S3. Mole weight: 1098.27. | |
| TAG-1 A2 (78-86) | | |
| TAG-2 (42-50) | | |
| Talin (777-785) | Talin (777-785) is a peptide derived from Talin which is a mechanosensitive protein. Its mechanical vulnerability and cellular position bridging integrin receptors and the actin cytoskeleton make it a fundamental protein in mechanotransduction. This peptide can be used in Ovarian carcinoma research. | |
| Taltirelin | Taltirelin is a thyrotropin-releasing hormone receptor (TRH-R) superagonist with an IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic Ca2+ concentration (Ca2+ release). Synonyms: N-[[(4S)-Hexahydro-1-methyl-2,6-dioxo-4-pyrimidinyl]carbonyl]-L-histidyl-L-prolinamide; (S)-N-[(Hexahydro-1-methyl-2,6-dioxo-4-pyrimidinyl)carbonyl]-L-histidyl-L-prolinamide; (4S)-Hexahydro-1-methyl-2,6-dioxo-4-pyrimidinecarbonyl-L-histidyl-L-prolinamide; Ceredist; TA 0910; (S)-N-((S)-1-((S)-2-Carbamoylpyrrolidin-1-yl)-3-(1H-imidazol-4-yl)-1-oxopropan-2-yl)-1-methyl-2,6-dioxohexahydropyrimidine-4-carboxamide; 1-methyl-(S)-4,5-dihydroorotyl-L-histidyl-L-prolinamide. Grades: >98%. CAS No. 103300-74-9. Molecular formula: C17H23N7O5. Mole weight: 405.41. | |
| TAMRA-β-Amyloid (1-42), human | TAMRA-β-Amyloid (1-42), human is the main component of amyloid plaque, which accumulates in neurons of the brain of Alzheimer's disease. Grades: ≥95%. CAS No. 1802087-80-4. Molecular formula: C228H331N57O64S. Mole weight: 4926.46. | |
| TAMRA-dT | TAMRA-dT - an ingenious fluorescently labeled nucleotide indispensable in diverse biochemical research applications for its versatility in nucleic acid labeling and detection. Its sophisticated features enable efficient complementary DNA (cDNA) production in powerful molecular biology techniques utilizing reverse transcriptase. Moreover, its unique properties facilitate the development of advanced nucleic acid probes for the diagnosis of life-threatening diseases such as cancer, HIV, and hepatitis B. Synonyms: 5'-Dimethoxytrityloxy-5-[N-((tetramethylrhodaminyl)-aminohexyl)-3-acrylimido]-2'-deoxyUridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C73H83N8O13P. Mole weight: 1311.48. | |
| Taspoglutide | Taspoglutide is a long-acting glucagon-like peptide 1 (GLP-1) receptor agonist (EC50 = 0.06 nM) under investigation for treatment of type 2 diabetes. Synonyms: (N-((N-(L-histidyl)-2-aminoisobutyryl)-L-alpha-glutamyl-glycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-alpha-glutamyl-glycyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-alpha-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-lysyl)-2-aminoisobutyryl)-L-argininamide; H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Aib-Arg-NH2. CAS No. 275371-94-3. Molecular formula: C152H232N40O45. Mole weight: 3339.71. | |
| TAT 14 | TAT 14 is an Nrf2 activator and inhibits Nrf2/Keap1 interaction with neuroprotective activity. TAT 14 has been shown to induce upregulation of Nrf2 pathway downstream gene expression including heme-oxygenase 1 and suppress LPS-induced TNF-α expression in THP-1 cells. Synonyms: TAT14; TAT-14; H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Leu-Gln-Leu-Asp-Glu-Glu-Thr-Gly-Glu-Phe-Leu-Pro-Ile-Gln-OH; L-tyrosyl-glycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginyl-L-leucyl-L-glutaminyl-L-leucyl-L-alpha-aspartyl-L-alpha-glutamyl-L-alpha-glutamyl-L-threonyl-glycyl-L-alpha-glutamyl-L-phenylalanyl-L-leucyl-L-prolyl-L-isoleucyl-L-glutamine; TAT 14 Peptide (Nrf2 Activator III). Grades: ≥95%. CAS No. 1362661-34-4. Molecular formula: C137H230N48O39. Mole weight: 3173.59. | |
| TAT-cyclo-CLLFVY | TAT-cyclo-CLLFVY has been found to be a HIF-1 dimerization inhibitor and could block protein-protein interaction of recombinant HIF-1&alpha. Synonyms: TAT-cyclo-CLLFVY; 1446322-66-2; AKOS027470216; PD079835. Grades: ≥95% by HPLC. CAS No. 1446322-66-2. Molecular formula: C111H188N42O24S2. Mole weight: 2559.10. | |
| TAT-Gap19 | TAT-Gap19 is a brain penetrating Cx43 hemichannel blocker (IC50 ~7 μM) with no significant affinity for gap junctions or Panx1 channels. Synonyms: H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Lys-Gln-Ile-Glu-Ile-Lys-Lys-Phe-Lys-OH; L-tyrosyl-glycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginyl-L-lysyl-L-glutaminyl-L-isoleucyl-L-alpha-glutamyl-L-isoleucyl-L-lysyl-L-lysyl-L-phenylalanyl-L-lysine. Grades: 97%. CAS No. 1507930-54-2. Molecular formula: C119H212N46O26. Mole weight: 2703.28. | |
| TC 14012 | TC 14012 is an antagonist of CXCR4. Synonyms: TC 14012; TC14012; TC-14012; L- arginyl- L- arginyl- 3- (2- naphthalenyl)- L- alanyl- L- cysteinyl- L- tyrosyl- N5- (aminocarbonyl)- L- ornithyl- L- lysyl- N5- (aminocarbonyl)- D- ornithyl- L- prolyl- L- tyrosyl- L- arginyl- N5- (aminocarbonyl)- L- ornithyl- L- cysteinyl- cyclic (4?1. Grades: >95%. CAS No. 368874-34-4. Molecular formula: C90H140N34O19S2. Mole weight: 2066.43. | |
| tC°-CE Phosphoramidite | tC°-CE Phosphoramidite, a chemical reagent essential in oligonucleotide synthesis for biomedical applications, boasts a thermally cleavable protecting group enabling streamlined purification and deprotection of the end product. Its widespread usage extends to the creation of RNA and DNA probes, utilized regularly in the diagnosis and treatment of maladies such as cancer and viral infections. Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-1'-(1,3-diaza-2-oxophenoxazin-1-yl)-2'-deoxy-ß-D-ribofuranosyl-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C45H50N5O8P. Mole weight: 819.88. | |
| tC-CE Phosphoramidite | tC-CE Phosphoramidite, a bioorganic compound vital to the biomedicine industry, plays a significant role in synthesizing oligonucleotides used for studying and diagnosing various diseases, ranging from cancer to genetic disorders. Through its unique fluorescent properties, it offers an unparalleled capability to detect and analyze DNA and RNA sequences, unveiling new horizons in the field of bioanalytics. Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-1'-(1,3-diaza-2-oxophenothiazin-1-yl)-2'-deoxy-ß-D-ribofuranosyl-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C45H50N5O7PS. Mole weight: 835.95. | |
| TC E3 5031 | TC E3 5031 is a proteolysis targeting chimeras which allows for the optical control of protein degradation. Synonyms: 2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetic acid; E3 ligase Ligand 3; Acetic acid, 2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-; Thalidomide-O-COOH; Thalidomide-Acid; SCHEMBL14085581; Thalidomide-O-COOH (Cereblon ligand 3); 2-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetic acid. Grades: ≥ 98%. CAS No. 1061605-21-7. Molecular formula: C15H12N2O7. Mole weight: 332.26. | |
| tCnitro-CE Phosphoramidite | tCnitro-CE Phosphoramidite, a reagent vital for the synthesis of oligonucleotides, features a promising nitro group situated at the 5'-end capable of introducing a modification or label. Its applications in nucleic acid-based technologies like gene editing and diagnostics research remain unparalleled. Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-1'-(7-nitro-1,3-diaza-2-oxophenothiazin-1-yl)-2'-deoxy-ß-D-ribofuranosyl-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C45H49N6O9PS. Mole weight: 880.94. | |
| tCnitroNucleoside | tCnitroNucleoside is a multifaceted biomedical compound used to study cancer, viral infections and genetically rooted ailments. Grades: ≥ 95%. CAS No. 1139889-25-0. Molecular formula: C15H14N4O6S. Mole weight: 378.36. | |
| TDFA | TDFA is a protein arginine deiminase 4 (PAD4) inhibitor (IC50 = 2.3, 8.5, 26 and 71 μM for PAD4, PAD1, PAD3 and PAD2, respectively) used for the treatment of autoimmune disorders. Synonyms: (3S)-3-[[(2S,3R)-2-acetamido-3-hydroxybutanoyl]amino]-4-[[(2S)-1-amino-5-[(1-amino-2-fluoroethylidene)amino]-1-oxopentan-2-yl]amino]-4-oxobutanoic acid. CAS No. 1345019-64-8. Molecular formula: C17H29FN6O7. Mole weight: 448.45. | |
| TDP-a-D-fucose ammonium salt | TDP-a-D-fucose ammonium salt, a biochemical with vast utility in the synthesis of fucosylated biomolecules, is a substrate analog with proven efficacy in measuring the activity of fucosyltransferases, central players in the biosynthesis of glycan structures found in glycoproteins and glycolipids. In addition, this product has been demonstrated to be of major significance in foundational research related to cancer, immune response, and host-pathogen interactions. Molecular formula: C16H32N4O16P2. Mole weight: 598.39. | |
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