BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
5-Deoxy-L-ribose phenylhydrazone, an intriguing compound, has been the subject of numerous biomedical research studies, aimed at elucidating its impact on cellular metabolism, specifically glucose transport and metabolism. Additionally, this multifaceted compound has ignited significant interest due to its potential to treat diverse maladies, including cancer, owing to its tumor growth-inhibiting properties and apoptosis-inducing abilities. Synonyms: 5-deoxy-L-ribose phenylhydrazone; L-Ribose, 5-deoxy-, phenylhydrazone; 123168-30-9; (1E,2R,3S,4S)-1-(phenylhydrazinylidene)pentane-2,3,4-triol; SCHEMBL9501969; L-Ribose,5-deoxy-,phenylhydrazone; AMY18688; A890850. CAS No. 123168-30-9. Molecular formula: C11H16N2O3. Mole weight: 224.26.
5'-DMT-2'-O-TBDMS-PseudoUridine-CE-Phosphoramidite is a valuable compound primarily employed for the research and development of RNA molecules required for diagnostic purposes or therapeutic interventions. This compound plays a crucial role in the development of drugs targeting specific diseases and disorders, such as cancers or viral infections. It facilitates efficient nucleotide incorporation and ensures accurate development of RNA sequences. Synonyms: 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-pseudoUridine 3'-CE phosphoramidite; PseudoUridine-CE Phosphoramidite; Pseudouridine CEP; 5-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-beta-D-ribofuranosyl]-2,4(1H,3H)-pyrimidinedione. Grades: ≥95%. CAS No. 163496-23-9. Molecular formula: C45H61N4O9PSi. Mole weight: 861.05.
5-Dodecyldihydro-2(3H)-Furanone
5-Dodecyldihydro-2(3H)-Furanone, a chemically synthesized organic compound, exhibits remarkable antibacterial, antifungal, and antiviral activities. This exceptionally versatile compound has been the subject of in-depth research for its potential therapeutic application in combating drug-resistant bacterial infections and mitigating biofilm formation in diverse microbial communities, imparting outstanding promise for numerous industrial and healthcare applications. Synonyms: gamma-Palmitolactone; 2(3H)-Furanone, 5-dodecyldihydro-; 5-Dodecyldihydro-2(3H)-furanone. CAS No. 730-46-1. Molecular formula: C16H30O2. Mole weight: 254.41.
5-Ethyluridine
5-Ethyluridine, a remarkable biomedicine, occupies a pivotal position in the scientific realm, facilitating extensive exploration of pharmacological realms. Notably, this compound finds widespread employment in the synthesis and formulation of antiviral agents, with a particular focus on countering the perilous human immunodeficiency virus (HIV). Synonyms: Uridine, 5-ethyl-; 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-ethylpyrimidine-2,4(1H,3H)-dione. Grades: ≥95%. CAS No. 25110-76-3. Molecular formula: C11H16N2O6. Mole weight: 272.25.
5-Formyl-dC
5-Formyl-dC, an indispensable reagent in the biomedicine field, occupies a pivotal position owing to its unparalleled characteristics. Its significance lies in facilitating the synthesis of tailored nucleic acids, thereby facilitating in-depth exploration of various research domains. Remarkably, this compound imparts unprecedented opportunities for the discovery of novel therapeutic agents and diagnostic instruments targeting a broad spectrum of ailments spanning cancer and hereditary anomalies. Synonyms: fdC; 5-Formyl-2'-deoxycytidine. Grades: ≥ 95% by HPLC. CAS No. 137017-45-9. Molecular formula: C10H13N3O5. Mole weight: 255.23.
5-Hydroxy-2-adamantanone
Idramantone, an immune agonist, can be used to prepare adamantane substituted guanylhydrazones. Synonyms: 5-hydroxyadamantan-2-one. CAS No. 20098-14-0. Molecular formula: C10H14O2. Mole weight: 166.22.
5-Hydroxy-Clethodim Sulfone
5-Hydroxy-clethodim Sulfone is an impurity of Clethodim, a post-emergent herbicide. Synonyms: 2-[1-[[(3-Chloro-2-propen-1-yl)oxy]imino]propyl]-5-[2-(ethylsulfonyl)propyl]-3,5-dihydroxy-2-cyclohexen-1-one. Grades: > 95%. CAS No. 111031-11-9. Molecular formula: C17H26ClNO6S. Mole weight: 407.91.
5-Hydroxy-Clethodim Sulfoxide
5-Hydroxy-clethodim Sulfoxide is an impurity of Clethodim, a post-emergent herbicide. Synonyms: 2-[1-[[(3-Chloro-2-propen-1-yl)oxy]imino]propyl]-5-[2-(ethylsulfinyl)propyl]-3,5-dihydroxy-2-cyclohexen-1-one. Grades: > 95%. CAS No. 111031-08-4. Molecular formula: C17H26ClNO5S. Mole weight: 391.91.
5-Hydroxydopamine hydrochloride
5-Hydroxydopamine hydrochloride (CAS# 5720-26-3 ) is a useful research chemical. Synonyms: 5-(2-aminoethyl)benzene-1,2,3-triol;hydrochloride. CAS No. 5720-26-3. Molecular formula: C8H12ClNO3. Mole weight: 205.64.
5-Hydroxyisophthalic acid
5-Hydroxyisophthalic acid is used as a reagent in the synthesis of silver carboxylate metal organic framework (MOF) complexes. 5-Hydroxyisophthalic Acid is also used as the starting material in the synthesis of N,N'-Bis(2,3-dihydroxypropyl)-5-[(N-(2-hydroxyethyl)carbamoyl)methoxy]-2,4,6-triiodoisophthalamide. It is a compound related to Ioversol which is a nonionic, low osmolality, radiographic contrast agent. Synonyms: 5-Oxyisophthalic acid; 1,3-Benzenedicarboxylic acid, 5-hydroxy-. Grades: 97 %. CAS No. 618-83-7. Molecular formula: C8H6O5. Mole weight: 182.13.
5-Hydroxymethyldeoxyuridylate
5-Hydroxymethyldeoxyuridylate is a pivotal nucleotide in DNA bioresearch and repair, emerging as a substrate indispensable for diverse enzymes implicated in DNA methylation and demethylation cascades. Synonyms: 5-hydroxymethyluridine-2'-deoxy-5'-phosphate; 5-hydroxymethyl-dUMP. CAS No. 5238-86-8. Molecular formula: C10H15N2O9P. Mole weight: 338.21.
5-(Hydroxymethyl)dihydrofuran-2(3H)-one
5-(Hydroxymethyl)dihydrofuran-2(3H)-one is a paramount precursor in the construction of pharmaceuticals and natural products. It has been adeptly employed in the generation of prodrugs and as a ligand in transition metal catalyzed reactions. Moreover, its congeners have demonstrated encouraging bioactivities against diverse ailments, such as cancer and neurodegenerative disorders. Synonyms: 5-(hydroxymethyl)dihydrofuran-2(3H)-one; 5-(Hydroxymethyl)dihydro-2(3H)-furanone; 5-Hydroxymethyl-dihydro-furan-2-one. Grades: 95%. CAS No. 10374-51-3. Molecular formula: C5H8O3. Mole weight: 116.11.
5-Hydroxytoluene-2,4-disulfonic acid
5-Hydroxytoluene-2,4-disulfonic acid, a chemical compound extensively utilized in the pharmaceutical sector as an intermediary for the synthesis of several drugs, comprising dapsone and sulfoxone, attracts increasing interest due to its prospective employment as an antioxidant in cosmetic and food applications. Synonyms: 4-Hydroxy-6-methylbenzene-1,3-disulfonic acid. CAS No. 15509-33-8. Molecular formula: C7H8O7S2. Mole weight: 268.3.
5'-Iodo-2',3'-dideoxycytidine
It can be used as an antibiotic, and it is particularly effective against mycobacteria. Synonyms: 2',3'-dideoxy-5-iodocytidine; 5'-Iddc; 4-Amino-1-((2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodopyrimidin-2(1H)-one; IddC; 5-Iodo-2',3'-Dideoxy-D-Cytidine. Grades: ≥95%. CAS No. 114748-57-1. Molecular formula: C9H12IN3O3. Mole weight: 337.11.
5-Iodo-2'-deoxytubercidin
It is a derivative of 7-Iodo-7-deazadenine and is designed to be incorporated into DNA by using Vent(exo-) polymerase primers extension. Uses: Pharmaceutical intermediates. Synonyms: 4-Amino-5-iodo-7-(2-deoxy-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine; 2'-Deoxy-7-fluorotubercidin; 7-Iodo-7-deaza-2'-deoxyadenosine; 7-Deaza-2'-deoxy-7-iodoadenosine; 7-Iodo-2'-deoxy-7-carbaadenosine; (2R,3S,5R)-5-(4-Amino-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol; 7-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-4-amine. Grades: ≥95%. CAS No. 166247-63-8. Molecular formula: C11H13IN4O3. Mole weight: 376.15.
5-Methoxycarbonylmethyluridine
5-Methoxycarbonyl methyl uridine is a nucleoside constituent of yeast transfer RNA. 5-Methoxycarbonyl methyl uridine is also a derivative of 5-carboxymethyluridine, a carboxyl-containing nucleoside that was isolated from transfer RNA of Baker's Yeast. Synonyms: 5-(Methoxycarbonyl)methyluridine (MCM5U); Uridine 5-acetic acid methyl ester; 1,2,3,4-Tetrahydro-2,4-dioxo-1-beta-D-ribofuranosyl-5-pyrimidineacetic acid methyl ester; 5-(2-methoxy-2-oxoethyl)uridine; 5-Mcmu; Methyl 2-(1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetate. Grades: ≥95%. CAS No. 29428-50-0. Molecular formula: C12H16N2O8. Mole weight: 316.26.
5-methoxyflavone
5-methoxyflavone is a novel DNA polymerase-beta inhibitor and neuroprotective agent against beta-amyloid toxicity. Synonyms: 4H-1-Benzopyran-4-one, 5-methoxy-2-phenyl-; 5-Methoxy-2-phenyl-4H-1-benzopyran-4-one; Flavone, 5-methoxy-. Grades: ≥98%. CAS No. 42079-78-7. Molecular formula: C16H12O3. Mole weight: 252.26.
5-methoxyuridine
5-Methoxyuridine is an analog of Uridine and is used as a reagent in the synthesis of 5-OMe-UDP, a potent and selective P2Y6-receptor agonist. Synonyms: Uridine, 5-methoxy-; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methoxypyrimidine-2,4(1H,3H)-dione; 5-Methoxyuridine. Grades: ≥95%. CAS No. 35542-01-9. Molecular formula: C10H14N2O7. Mole weight: 274.23.
5-methyl-2'-deoxycytidine-5'-monophosphate
5-methyl-2'-deoxycytidine-5'-monophosphate is a crucial compound in biomedicine used for various applications. As a modified nucleotide analogue, it plays a vital role in DNA methylation processes, making it fundamental for epigenetic studies and research. Additionally, this product is involved in the regulation of gene expression and has potential therapeutic significance in treating diseases such as cancer, neurodegenerative disorders, and viral infections. Synonyms: 5-Me-2'-dCMP; 2'-Deoxy-5-methylcytidine-5'-monophosphate; 5-MedCMP; 2'-deoxy-5-methylcytidine 5'-(dihydrogen phosphate); 2'-deoxy-5-methyl-5'-cytidylic acid; 5-Methyl dCMP. Grades: ≥95% by HPLC. CAS No. 2498-41-1. Molecular formula: C10H16N3O7P. Mole weight: 321.22.
5-Methyl-2'-Fluoro-U Phosphoramidite
5-Methyl-2'-Fluoro-U Phosphoramidite, a pivotal compound with paramount significance in the domain of biomedicine, assumes the role of a fundamental constituent within the intricate framework of synthesized nucleic acids. Its exceptional utility lies in its indispensable contribution to the progressive advancement of antisense oligonucleotide development. Notably, this phosphoramidite possesses an intrinsic capacity to effectively combat a myriad of ailments encompassing viral infections and genetic disorders, by selectively targeting specified genes or RNA sequences. Synonyms: 2'-Fluoro-dT Phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-2'-fluoro-5-methyluridine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Grades: 95%. CAS No. 182700-06-7. Molecular formula: C40H48FN4O8P. Mole weight: 762.8.
An impurity of Olmesartan, which is a specific angiotensin II type 1 (AT1) receptor antagonist with antihypertensive effect. CAS No. 1040405-56-8. Molecular formula: C49H46N6O6. Mole weight: 814.93.
An impurity of Edaravone, a medication for the recovery from stroke. Synonyms: 3,3'-dimethyl-1,1'-diphenyl-1h,1'h-4,4'-bipyrazole-5,5'-diol. CAS No. 177415-76-8. Molecular formula: C20H18N4O2. Mole weight: 346.39.
5-methylaminomethyl-2-thiouridine
5-methylaminomethyl-2-thiouridine, an indispensable compound in biomedicine, serves as a linchpin for scientific advancements. With widespread application in the exploration of antiviral agents and remedies for diverse ailments, this compound assumes a pivotal function. By enhancing the effectiveness of therapeutic interventions against viral infections, it unravels intricate mechanisms underlying drug action. Synonyms: 5-(Methylaminomethyl)-2-thiouridine; 2-Thio-5-(N-methylaminomethyl)uridine; 5-N-Methylaminomethyl-2-thiouridine; 2-Thio-5-methylaminomethyluridine; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-((methylamino)methyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one; 5-[(Methylamino)methyl]-1-(β-D-ribofuranosyl)-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone. Grades: ≥95%. CAS No. 32860-54-1. Molecular formula: C11H17N3O5S. Mole weight: 303.34.
5-[Methylidene]thiazolidine-2,4-dione
5-[Methylidene]thiazolidine-2,4-dione, a thiazolidinedione derivative, exhibits remarkable pharmaceutical potential in tackling diabetes via targeting the PPAR-γ protein responsible for maintaining glucose homeostasis. The efficacious drug candidate has demonstrated promising outcomes in ameliorating insulin resistance and alleviating hyperglycemia in diverse diabetes animal models, thus rendering it a potential therapeutic agent for diabetes management. Synonyms: 5-(2-nitrobenzylidene)-1,3-thiazolidine-2,4-dione. CAS No. 36140-65-5. Molecular formula: C10H6N2O4S. Mole weight: 250.228.
5-(N,N-dimethyl)-amiloride hydrochloride
Cas No. 2235-97-4.
5-(N,N-Hexamethylene)-amiloride
5-(N,N-Hexamethylene)-amiloride derives from an amiloride and is a potent Na+/H+ exchanger inhibitor, which decreases the intracellular pH (pHi) and induces apoptosis in leukemic cells. It is also an inhibitor of the HIV-1 Vpu virus ion channel and inhibits mouse hepatitis virus (MHV) replication and human coronavirus 229E (HCoV229E) replication in cultured L929 cells with EC50s of 3.91 μM and 1.34 μM, respectively. Synonyms: Hexamethylene amiloride; HMA. Grades: 0.98. CAS No. 1428-95-1. Molecular formula: C12H18ClN7O. Mole weight: 311.77.
5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-2'-fluorouridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite (CAS# 146954-75-8) is a useful research chemical. Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-2'-fluorouridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite; 2'-F-dU Phosphoramidite; DMT-2'Fluoro-dU Phosphoramidite; 5'-O-Dimethoxytrityl-2'-fluoro-2'-deoxyuridine 3'-CE phosphoramidite; 2'-Deoxy-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-fluorouridine 3-CE phosphoramidite; DMT-2'-Fluoro-dU amidite. Grades: ≥ 98 %. CAS No. 146954-75-8. Molecular formula: C39H46FN4O8P. Mole weight: 748.78.
5-(Octadecyloxy)isophthalic acid
The chemical compound, 5-(Octadecyloxy)isophthalic acid, holds significant promise for its therapeutic effects in cancer treatment. Its potent antiproliferative properties have demonstrated inhibitory effects on the growth of tumor cells and offer a prospective avenue for the treatment of diverse forms of cancer. Synonyms: 1,3-Benzenedicarboxylicacid, 5-(octadecyloxy)-; 5-octadecoxybenzene-1,3-dicarboxylic Acid; 5-Stearyloxyisophthalic acid. CAS No. 143294-86-4. Molecular formula: C26H42O5. Mole weight: 434.617.
5-O-Desmethyl Omeprazole
5-O-Desmethyl Omeprazole is an impurity of Omeprazole. Omeprazole is a proton pump inhibitor used in the treatment of dyspepsia. It binds to the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase) and inhibits its activity and the parietal cell secretion of H+ ions into the gastric lumen. Uses: A metabolite of omeprazole, an antiulcerative. Synonyms: 1H-Benzimidazol-6-ol, 2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-; 1H-Benzimidazol-5-ol, 2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-; 2-[[(4-Methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazol-6-ol; 5-O-Desmethylomeprazole. Grades: >90%. CAS No. 151602-49-2. Molecular formula: C16H17N3O3S. Mole weight: 331.39.
5'-O-DMT-2'-deoxyuridine-3'-CE Phosphoramidite
5'-O-DMT-2'-deoxyuridine-3'-CE Phosphoramidite stands as an indispensable entity within the realm of biomedicine, wherein its applications for the synthesis of nucleic acids in investigative capacities hold paramount significance. DNA and RNA oligonucleotides rely on this product as their cornerstone, as it seamlessly integrates 2'-deoxyuridine into nucleic acid sequences with exacting efficiency. Aiding the progression of pharmaceutical innovation, gene therapy, and genetic exploration, it emerges as an invaluable instrument that propels advancements in the remediation of diverse medical afflictions. Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine-3'-O-[O-(2-cyanoethyl)-N,N'-diisopropylphosphoramidite]; 2'-Deoxy-5'-O-DMT-uridine 3'-CE Phosphoramidite; DMT-dU Phosphoramidite; 5-O-(4,4'-dimethoxytrityl)-3-O-(diisopropylamino-2-cyanoethoxyphosphanyl)-1,2-dideoxy-1-uracil-1-yl-beta-D-erythro-pentofuranose; 3'-O-[(Diisopropylamino)(2-cyanoethoxy)phosphino]-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyuridine. Grades: ≥ 98%. CAS No. 109389-30-2. Molecular formula: C39H47N4O8P. Mole weight: 730.8.
5'-O-DMT-2'-fluoro-N2-isobutyryl-2'-Deoxy-guanosine 3'-CE phosphoramidite is a novel nucleoside analog for the incorporation of 2-fluoro-modified ribose-G nucleobases within oligonucleotides. Synonyms: 2'-Deoxy-5'-O-DMT-2'-fluoro-N2-isobutyrylguanosine 3'-CE phosphoramidite; 2'-F-iBu-G-CEP; 5'-O-[bis(4-methoxyphenyl)?phenylmethyl]?-2'-deoxy-2'-fluoro-N-(2-methyl-1-oxopropyl)?-Guanosine 3'-[2-cyanoethyl N,?N-bis(1-methylethyl)?phosphoramidite]; DMT-2'Fluoro-dG(ib) Phosphoramidite. Grades: 95%. CAS No. 144089-97-4. Molecular formula: C44H53FN7O8P. Mole weight: 857.91.
5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine 3'-CE phosphoramidite can introduce uridine units into the building blocks of non-natural DNA and RNA chains. Synonyms: 5'-O-(4,4'-Dimethoxytriphenylmethyl)-2'-O-(2-methoxyethyl)-5-methyluridin-3'-yl]-2-cyanoethyl-N,N'-diisopropylphosphoramidite; 5'-O-DMT-2'-MOE-thymidine 3'-CE phosphoramidite; DMT-2'-O-MOE-T-CEP; 5-Me-DMT-2'-O-MOE-U-CE P. Grades: ≥98% by HPLC. CAS No. 163878-63-5. Molecular formula: C43H55N4O10P. Mole weight: 818.89.
5'-O-DMT-2'-O-TBDMS-2-Thiouridine 3'-CE phosphoramidite is a phosphoramidite derivative used for the solid-phase research and development of modified RNA sequences. With its 5'-O-DMT protection, 2'-O-TBDMS modification and 2-thiouridine incorporation, it enables the controlled research and development of RNA molecules for studying RNA-protein interactions and RNA-based therapeutics targeting diseases like cancer and viral infections. Synonyms: Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-2-thio-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-2-thio-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]. CAS No. 163496-21-7. Molecular formula: C45H61N4O8PSSi. Mole weight: 877.11.
5'-O-DMT-2'-O-tBDMS-N1-Methyl-N6-chloroacetyl-adenosine 3'-CE phosphoramidite, an essential instrument employed in scientific inquiry and pharmaceutical exploration, exhibits an exceptionally intricate nature. Primarily, this remarkable compound facilitates the creation of tailored DNA fragments, thereby accommodating a diverse range of research endeavors involving gene therapy and pharmaceutical conveyance mechanisms. Notably, our product assumes a pivotal role in the design and fabrication of nucleotide analogs, which serve as targeted interventions for critical maladies, including malignancies, viral infestations, and hereditary abnormalities. Molecular formula: C49H65ClN7O8PSi. Mole weight: 974.59.
5'-O-DMT-5-Fluoro-2'-deoxyuridine-3'-CE Phosphoramidite is a highly potent reagent for the synthesis of 5-fluorouracil (5-FU) containing oligonucleotides, with potential applications in the treatment of cancer. By boosting the selectivity and efficacy of 5-FU, a well-established chemotherapy drug for different forms of cancer, this compound constitutes a promising avenue to enhance the therapeutic options available to patients. Synonyms: Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-fluoro-, 3'-[2-cyanoethylbis(1-methylethyl)phosphoramidite]; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-fluoro-uridine 3'-[2-cyanoethylbis(1-methylethyl)phosphoramidite]; FdU-amidite; NSC-729744. Grades: ≥98% by HPLC. CAS No. 142246-63-7. Molecular formula: C39H46FN4O8P. Mole weight: 748.78.
5'-O-DMT-N2-DMF-2'-deoxyguanosine 3'-CE phosphoramidite, an indispensable constituent in the biomedical sector, finds extensive application in the synthesis of oligonucleotides for diagnostics and research studies. Its pivotal role encompasses the progress of nucleic acid-centered therapies and drug exploration, with a primary focus on combatting a wide range of diseases, encompassing cancer, genetic disorders, and viral infections. Synonyms: 5'-O-DMT-N2-(dimethylamino)-2'-Deoxy Guanosine Phosphoramidite; DMF-dG CEP; 5'-Dimethoxytrityl-N-dimethylformamidine-2'-deoxyGuanosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Dmf-dG-CE Phosphoramidite; 2'-Deoxy-N2-DMF-5'-O-DMT-guanosine 3'-CE phosphoramidite; 5'-O-[bis(4-methoxyphenyl)?phenylmethyl]?-2'-deoxy-N-[(dimethylamino)?methylene]?-Guanosine 3'-[2-cyanoethyl N,?N-bis(1-methylethyl)?phosphoramidite]. Grades: ≥98% by HPLC. CAS No. 330628-04-1. Molecular formula: C43H53N8O7P. Mole weight: 824.93.
5'-O-DMT-N2-isobutyryl-2'-O-methoxyethylguanosine 3'-CE phosphoramidite is used to incorporate 2'-O-methoxyethyl-modified G into oligonucleotides, which is useful for antisense RNA. Synonyms: 5'-O-DMTr-N2-iBu-2'-O-MOE-guanosine-3'-CED phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-N2-iso-butyroyl-2'-O-(2-methoxyethyl)guanosine-3'-O-[(2-cyanoethyl)(N,N-diisopropyl)]phosphoramidite; 2'-MOE-G(iBu)-3'-phosphoramidite; DMT-2M-O-Me-rG(ib) amidite; N2-isobutyryl-5'-O-DMT-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite; N-Isobutyryl-2'-O- (2-methoxyethyl)-3'-O-[2-cyanoethoxy (diisopropylamino)phosphino]-5'-O- (4, 4'-dimethoxytrityl)guanosine; 5'-O-[Bis (4-methoxyphenyl) (phenyl)methyl]-3'-O-[ (2-cyanoethoxy) (diisopropylamino)phosphino]-N-isobutyryl-2'-O- (2-methoxyethyl)guanosine. Grades: ≥95%. CAS No. 251647-55-9. Molecular formula: C47H60N7O10P. Mole weight: 913.99.
5'-O-DMT-N2-isobutyrylguanosine
5'-O-DMT-N2-isobutyrylguanosine is a biomedicine product commonly used in the field of nucleic acid research. This compound is a modified form of guanosine and is often utilized as a substrate to study various enzymatic reactions related to DNA and RNA synthesis. It plays a crucial role in investigating the functions of guanine derivatives, offering insights into potential therapeutic approaches for diseases involving nucleic acid metabolism. Synonyms: N2-iso-Butyryl-5'-O-(4,4'-dimethoxytrityl)guanosine; 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-guanosine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-N-(2-methyl-1-oxopropyl)-guanosine; N-[9-[(2R,3R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3,4-dihydroxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide. Grades: ≥95%. CAS No. 81246-83-5. Molecular formula: C35H37N5O8. Mole weight: 655.70.
5'-O-DMT-N4-Acetyl-2'-fluoro-2'-deoxy-cytidine 3'-CE phosphoramidite is a phosphoramidite compound used to introduce 2-fluoro-modified nucleotides into oligonucleotides. Synonyms: N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine 3'-CE phosphoramidite; 2'-F-Ac-dC CE phosphoramide; 2'-F-Ac-dC Phosphoramidite; Dmt-2'-f-dc(ac) amidite; DMT-2'Fluoro-dC(ac) Phosphoramidite. Grades: ≥98% by HPLC. CAS No. 159414-99-0. Molecular formula: C41H49FN5O8P. Mole weight: 789.83.
5'-O-DMT-N4-Benzoyl-5-Methy-2'-O-(2-methoxyethyl)cytidine 3'-CE phosphoramidite is used to incorporate methyl-C modified with 2'-O-methoxyethyl into oligonucleotides, which is useful for anti-sense RNA. Synonyms: N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine 3'-CE phosphoramidite; 2'-O-MOE-N4-Bz-5-Me-C Phosphoramidite; 5-Me-DMT-2'-O-MOE-C(Bz)-CEP; N4-Benzoyl-5-methyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyl-cytidine-3'-cyanoethyl phosphoramidite; N-Benzoyl-5'-O-[bis (4-methoxyphenyl) (phenyl)methyl]-3'-O-[ (2-cyanoethoxy) (diisopropylamino)phosphino]-2'-O- (2-methoxyethyl)-5-methyl-3, 4-dihydrocytidine. Grades: ≥98% by HPLC. CAS No. 163759-94-2. Molecular formula: C50H60N5O10P. Mole weight: 922.01.
5'-O-DMT-N6-Benzoyl-2'-deoxyadenosine 3'-CE phosphoramidite, an indispensable biomolecular tool, profoundly impacts the dynamic biomedical sphere. Its paramount significance lies in its pivotal role as a reagent for nucleoside or oligonucleotide synthesis, revolutionizing the study of DNA-protein interactions, gene expression, and research in molecular biology. Synonyms: N6-Benzoyl-5'-O-DMT-2'-deoxyadenosine 3'-CE phosphoramidite; dA(Bz) CEP; 5'-Dimethoxytrityl-N-benzoyl-2'-deoxyAdenosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)?phenylmethyl]?-2'-deoxy-adenosine 3'-[2-cyanoethyl N,?N-Bis(1-methylethyl)?phosphoramidite]; DMT-dA(bz) Phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-deoxyadenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite. Grades: ≥98% by HPLC. CAS No. 98796-53-3. Molecular formula: C47H52N7O7P. Mole weight: 857.93.
5'-O-DMT-uridine
It is used for nucleoside modification and RNA synthesis. Synonyms: 5'-O-DMT uridine; 5'-O-(4,4'-Dimethyltrityl)uridine; 5'-O-DMT-D-uridine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]uridine; 1- ( (2R, 3R, 4S, 5R)-5- ( (bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-3, 4-dihydroxytetrahydrofuran-2-yl)pyrimidine-2, 4 (1H, 3H)-dione. Grades: ≥98% by HPLC. CAS No. 81246-79-9. Molecular formula: C30H30N2O8. Mole weight: 546.57.
5S rRNA modificator
5S rRNA modificator is a suitable electrophile for 2'-hydroxyl acylation on structured RNA molecules, yielding accurate structural information comparable to that obtained with existing probes; 5S rRNA RNA modification. Synonyms: 5S rRNA modificator. Grades: >98%. CAS No. 1415238-77-5. Molecular formula: C9H8N2O2. Mole weight: 176.17.
5'-Thymidylic acid, disodium salt
5'-Thymidylic acid, disodium salt is a paramount biomedical compound, playing the role of a nucleotide analog. It exerts its inhibitory prowess on viral DNA replication, thereby impeding the rampant multiplication of the virus. Synonyms: Thymidine-5'-monophosphate disodium salt; sodium ((2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl phosphate. Grades: ≥97% by HPLC. CAS No. 33430-62-5. Molecular formula: C10H13N2Na2O8P. Mole weight: 366.17.
5-Trans Bimatoprost
5-Trans Bimatoprost is the trans-isomer used in the improved process for the production and purification of Bimatoprost. Synonyms: (5E)-BiMatoprost; 5-trans-17-phenyl trinor Prostaglandin F2α ethyl amide; (5E)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-N-ethyl-5-heptenaMide. Grades: > 95%. CAS No. 1163135-95-2. Molecular formula: C25H37NO4. Mole weight: 415.58.
6, 13-Bis (triisopropylsilylethynyl)pentacene
6, 13-Bis (triisopropylsilylethynyl)pentacene is a multifaceted organic semiconductor that demonstrates exceptional efficacy within electronic devices. This particular compound has received immense attention due to its capacity to remarkably enhance the operation of various devices, including field-effect transistors, photovoltaic cells, and organic light-emitting diodes. Over the years, it has proven to be quite useful within research expeditions concerned with materials science and analytical chemistry alike. Synonyms: TIPS pentacene. Grades: 95%. CAS No. 373596-08-8. Molecular formula: C44H54Si2. Mole weight: 639.07.
6-[(3R,4R)-3-(Acetyloxy)-N,4-dimethyl-6-oxo-L-norleucine] Cyclosporin A
6-[(3R,4R)-3-(Acetyloxy)-N,4-dimethyl-6-oxo-L-norleucine] Cyclosporin A is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: (2S, 5R, 8S, 11S, 14S, 17S, 20S, 26S, 29S, 32S)-8, 11, 26, 32-Tetraisobutyl-20-ethyl-14, 29-diisopropyl-2, 5, 7, 10, 13, 16, 22, 25, 31-nonamethyl-17-[(1R, 2R)-1-acetoxy-2-methyl-4-oxobutyl]-1, 4, 7, 10, 13, 16, 19, 22, 25, 28, 31-undecaazacyclotritriacontane-3, 6, 9, 12, 15, 18, 21, 24, 27, 30, 33-undecaone; Cyclosporine EP Impurity A; Cyclosporin A, 6-[(3R,4R)-3-(acetyloxy)-N,4-dimethyl-6-oxo-L-norleucine]-; Acetyl Cyclosporin A aldehyde. Grades: 98%. CAS No. 121584-52-9. Molecular formula: C62H109N11O14. Mole weight: 1232.59.
6-(4-((5-amino-5-oxopentyl)amino)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide is a metabolite of Apixaban, a direct factor Xa inhibitor used as an anticoagulant for the prevention of venous thromboembolism and stroke in atrial fibrillation. Synonyms: 6-{4-[(5-Amino-5-oxopentyl)amino]phenyl}-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide; Des(2-oxo-1-piperidinyl)6-(4-(5-Amino-5-oxopentyl))Apixaban. CAS No. 2187409-01-2. Molecular formula: C25H28N6O4. Mole weight: 476.53.
666-15
666-15 is a potent and selective inhibitor of CREB-mediated gene transcription (IC50 = 81 nM) with efficacious in vitro and in vivo anti-breast cancer activity without harming normal cellular homeostasis. Synonyms: 66615; 666 15; 666-15; 3-(3-aminopropoxy)-N-[2-[3-[(4-chloro-2-hydroxyphenyl)carbamoyl]naphthalen-2-yl]oxyethyl]naphthalene-2-carboxamide;hydrochloride. CAS No. 1433286-70-4. Molecular formula: C33H31Cl2N3O5. Mole weight: 620.52.
6,7-Dihydro-1H,5H-pyrrolo[2,3-c]azepine-4,8-dione
6,7-Dihydro-1H,5H-pyrrolo[2,3-c]azepine-4,8-dione, an organic compound of petite stature, finds widespread employment as a fundamental constituent in the production of diverse healing agents. Its competence as an anticonvulsant is well-documented and it serves as a propitious precursor in the construction of topoisomerase inhibitors and neuroprotective remedies. Synonyms: Aldisin; 6,7-dihydropyrrolo[2,3-c]azepine-4,8(1H,5H)-dione; Pyrrolo[2,3-c]azepine-4,8(1H,5H)-dione, 6,7-dihydro-; 1H,4H,5H,6H,7H,8H-pyrrolo[2,3-c]azepine-4,8-dione. Grades: ≥95%. CAS No. 72908-87-3. Molecular formula: C8H8N2O2. Mole weight: 164.16.
6,7-Dimethyltetrahydropterin hydrochloride
6,7-Dimethyltetrahydropterin is a non-competitive inhibitor of GTP cyclohydrolase I exhibiting an IC50 of 76-112 μM. Synonyms: 2-Amino-6,7-dimethyl-5,6,7,8-tetrahydropteridin-4-ol hydrochloride. Grades: ≥99%. CAS No. 167423-51-0. Molecular formula: C8H13N5O·HCl. Mole weight: 231.7.
680C91
680C91 is a potent and selective inhibitor of TDO (Ki = 51 nM). Synonyms: (E)-3-(2-(1H-TETRAZOL-5-YL)VINYL)-6-FLUORO-1H-INDOLE. Grades: > 98%. CAS No. 163239-22-3. Molecular formula: C15H11FN2. Mole weight: 238.26.
6-Acetamidohexanoic acid
6-Acetamidohexanoic acid is used in inhibiting the Gastrointestinal disease like gastric ulcer or small bowel inflammation. It is often used after some oral administration of ZAC(zinc acexamate), an antiulcer agent. Uses: 6-acetamidohexanoic acid is used in inhibiting the gastrointestinal disease like gastric ulcer or small bowel inflammation. Synonyms: 6-(Acetylamino)hexanoic Acid; 6-Acetamidocaproic Acid; Acemin; Acetaminocaproic Acid; Acexamic Acid; CY 153; N-Acetyl-6-aminohexanoic Acid; AACA; N-Acetyl-ε-aminocaproic Αcid; NSC 12945; ε-Acetamidocaproic Acid. Grades: > 97%. CAS No. 57-08-9. Molecular formula: C8H15NO3. Mole weight: 173.21.
6-Aldehydoisoophiopogonanone A
6-Aldehydoisoophiopogonanone A is a compound of the flavonoid class found in the Ophiopogon japonicus. Synonyms: 6-Formylophiopogonanone A; 3-(1,3-benzodioxol-5-ylmethyl)-5,7-dihydroxy-8-methyl-4-oxo-2,3-dihydrochromene-6-carbaldehyde. Grades: >98%. CAS No. 116291-82-8. Molecular formula: C19H16O7. Mole weight: 356.33.
6α-Methylprednisolone 21-Hemisuccinate Sodium Salt
6α-Methylprednisolone 21-hemisuccinate, a derivative of prednisolone, is a kind of glucocorticoids. It has been developed for having longer half-life than that of Prednisolone and the potential anti-inflammatory effects. Uses: 6α-methylprednisolone 21-hemisuccinate is a kind of glucocorticoids and has been found to have potential anti-inflammatory effects. Synonyms: (6α,11β)-21-(3-Carboxy-1-oxopropoxy)-11,17-dihydroxy-6-methyl-pregna-1,4-diene-3,20-dione, Monosodium Salt; 11β,17,21-trihydroxy-6α-methyl-, 21-(hydrogen succinate)pregna-1,4-diene-3,20-dione Monosodium Salt; 11β,17,21-trihydroxy-6α-methyl-pregna-1,4-diene-3,20-dione 21-(Hydrogen Succinate) Sodium Salt; 6-Methylprednisolone Sodium Succinate; 6α-Methylprednisolone 21-Sodium Hemisuccinate; 6α-Methylprednisolone 21-Sodium Succinate; 6α-Methylprednisolone Sodium Hemisuccinate; 6α-Methylprednisolone Sodium Succinate; 6α-Methylpregnisolone 21-Sodium Succinate; Methylprednisolone Hemisuccinate Sodium; Methylprednisolone sodium succinate; Methylprednisolone succinate sodium; Metypred; NSC 48989; Sodium Methylprednisolone Succinate; Solu-Medrol; Solu-Medrone; U 9088; Urbason Solubile. Grades: ≥95%. CAS No. 2375-3-3. Molecular formula: C26H33NaO8. Mole weight: 496.53.
6α-Methyl Prednisone 21-Acetate
6α-Methyl Prednisone 21-Acetate is an impurity of Prednisone, which is a synthetic anti-inflammatory glucocorticoid used to treat inflammatory or immune-mediated responses, as well as endocrine or neoplastic diseases. Synonyms: 2-((6S,8S,9S,10R,13S,14S,17R)-17-hydroxy-6,10,13-trimethyl-3,11-dioxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta; (6α)-17-Hydroxy-6-methyl-3,11,20-trioxopregna-1,4-dien-21-yl acetate; Methylprednisolone Acetate EP Impurity K. Grades: 95%. CAS No. 115321-98-7. Molecular formula: C24H30O6. Mole weight: 414.49.
6-Amidino-2-Naphthol Methanesulfonic Acid
6-Amidino-2-naphthol methanesulfonic acid, a marvelously potent biological stain. It is oft harnessed for the powerful detection of arginine in amino acid sequences, affording scientists an unparalleled level of inquiry into the fundamental intricacies of protein structures. Notably, it facilitates a detailed exploration of the multifaceted functionality of arginine residues in such complex molecular ensembles. Synonyms: 6-Amidino-2-naphthol methanesulfonate; 6-Hydroxynaphthalene-2-carboxamidine mesylate; 6-Hydroxy-2-naphthimidamide methanesulfonate salt; 2-Naphthalenecarboximidamide, 6-hydroxy-, methanesulfonate (1:1) (salt). Grades: 95%. CAS No. 82957-06-0. Molecular formula: C12H14N2O4S. Mole weight: 282.32.
6-Amino-1,3-Naphthalenedisulfonic Acid Disodium Salt
An impurity of Pazopanib, which is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms. Synonyms: 2H-Indazol-6-amine, 2,3-dimethyl-, hydrochloride (1:1); 2H-Indazol-6-amine, 2,3-dimethyl-, monohydrochloride; 2,3-Dimethyl-2H-indazol-6-amine hydrochloride; 2,3-Dimethyl-6-amino-2H-indazole hydrochloride. Grades: ≥95%. CAS No. 635702-60-2. Molecular formula: C9H12ClN3. Mole weight: 197.66.
6-Aminoquinoline-N-hydroxy-succinimidyl carbamate
6-Aminoquinoline-N-hydroxy-succinimidyl carbamate is suitable for amino acid or protein sequence analysis by HPLC with fluorescence detection. Uses: 6-aminoquinoline-n-hydroxy-succinimidyl carbamate is used as derivatization regent for detecting hydrogen cyanamide in fruit. Synonyms: 2,5-Dioxopyrrolidin-1-yl quinolin-6-ylcarbamate; AQC; AHC reagent; AccQ.Fluor; AccQ·Tag. Grades: 95%. CAS No. 148757-94-2. Molecular formula: C14H11N3O4. Mole weight: 285.25.
6-Aza-2-thiothymine
6-Aza-2-thiothymine, a nucleoside analog widely utilized in cancer research, is profoundly effective in inhibiting thymidylate synthase; hence, it's active against several cancer cell lines. Furthermore, the compound's promising potential as a radiosensitizer renders it an excellent option for the management of solid tumors. This ground-breaking analog with unparalleled efficacy and versatility is a definitive focal point of modern-day cancer research. Synonyms: 2-Thio-6-azathymine; 6-Azathiothymine; 6-Methyl-3-thioxo-3,4-dihydro-1,2,4-triazin-5(2H)-one; 3-mercapto-6-methyl-1,2,4-triazin-5(4H)-one; 6-Methyl-3-thioxo-3,4-dihydro-2H-[1,2,4]triazin-5-one; 1,2,4-Triazin-5(2H)-one, 3,4-dihydro-6-methyl-3-thioxo-; NSC 1609; NSC 38618; 3-Mercapto-6-methyl-as-triazin-5-ol; NSC 102906; 3,4-Dihydro-6-methyl-3-thioxo-1,2,4-triazin-5(2H)-one; 6-Methyl-3-thio-as-triazine-3,5(2H,4H)-dione. CAS No. 615-76-9. Molecular formula: C4H5N3OS. Mole weight: 143.17.
6-Azidohexanoic acid NHS ester
A noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: N3-C5-NHS ester. Grades: ≥ 95% (HPLC). CAS No. 866363-70-4. Molecular formula: C10H14N4O4. Mole weight: 254.24.
6-(Benzyloxy)-4-(3-chloro-4-fluorophenylamino)-7-methoxy-quinazoline (CAS# 913819-12-2 ) is a useful research chemical. Synonyms: N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(phenylmethoxy)-4-quinazolinamine. Grades: 95 %. CAS No. 913819-12-2. Molecular formula: C22H17ClFN3O2. Mole weight: 409.84.
6-Bromohexylamine Hydrobromide
6-Bromohexylamine Hydrobromide, a prominent chemical compound utilized in biochemical research, serves as a key ingredient in the synthesis of multiple compounds such as 7-bromo-1-heptanol, 6-bromo-1-hexanol, and 7-bromo-1-heptylamine. With its innate capability to act as a primary raw material, it seeks extensive usage in the preparation of various biologically active agents, including N-(6-bromohexyl)propionamide and other medicinal drugs. Synonyms: 6-bromo-1-Hexanamine, Hydrobromide; 6-Bromohexylamine, Hydrobromide. Grades: 95%. CAS No. 14502-76-2. Molecular formula: C6H15Br2N. Mole weight: 261.0.