BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| BAY-850 | BAY-850 is a potent isotype-selective ATPase family AAA domain protein 2 (ATAD2) inhibitor with IC50 of 166 nM and can be used as a probe. Grades: 98%. CAS No. 2099142-76-2. Molecular formula: C38H44ClN5O3. Mole weight: 654.2. |  |
| BAY-985 | BAY-985 is a highly effective, orally active and selective TANK-binding kinase 1 (TBK1) and IκB kinase ε dual inhibitor, with anti-tumor activity. Synonyms: BAY985; GTPL10597; EX-A3294. Grades: ≥98% by HPLC. CAS No. 2409479-29-2. Molecular formula: C27H30F3N9O. Mole weight: 553.6. | |
| BayCysLT2 | BayCysLT2 is a potent and selective antagonist for the CysLT2R, which attenuates exacerbation of infarction damage to the myocardium caused by endothelial CysLT2R overexpression. CysLT2R can influence myocardial damage post-ischemia/reperfusion by mediating leukocyte adhesion and infiltration. CysLT2R can further blockade post-infarction maintains its protective properties, indicating a possible therapeutic role for CysLT2R antagonism. BayCysLT2 inhibits radioligand binding of LTD4 to CysLT2 and CysLT1 receptor cell lines with IC50 values of 35 and >10,000 nM, respectively. Synonyms: CAY10633; 3-[[(3-carboxycyclohexyl)amino]carbonyl]-4-[3-[4-(4-phenoxybutoxy)phenyl]propoxy]-benzoic acid. Grades: ≥95%. CAS No. 712313-33-2. Molecular formula: C34H39NO8. Mole weight: 589.7. | |
| Bayogenin 3-O-β-D-glucopyranoside | Bayogenin 3-O-β-D-glucopyranoside is a triterpenoid saponin isolated from the aerial parts of Polygala japonica Houtt. Synonyms: 2beta,23-Dihydroxy-3beta-(beta-D-glucopyranosyloxy)oleana-12-ene-28-oic acid. Grades: >98%. CAS No. 104513-86-2. Molecular formula: C36H58O10. Mole weight: 650.85. | |
| BAY-u 9773 | BAY-u 9773 is a non-selective cysteinyl leukotriene receptor antagonist displaying equal affinity for both CysLT1 and CysLT2 receptors (pKB = 6.8 and 6.5, respectively). BAY-u 9773 was investigated to inhibit bronchial and venous muscle contractions in human muscle preparations. BAY-u 9773 also acts as a competitive antagonist of LTC4- and LTE4-induced contractions of the guinea pig trachea. Synonyms: BAYu9773; BAY-u9773; BAY u9773. 4-[[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-Carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraen-1-yl]thio]benzoic acid; 6(R)-(4-Carboxyphenylthio)-5(S)-hydroxy-7(E),9(E),11(E),14(Z)-eicosatetraenoic acid. CAS No. 154978-38-8. Molecular formula: C27H36O5S. Mole weight: 472.64. | |
| BAZ2-ICR | BAZ2-ICR is a bromodomain inhibitor with IC50 of 130 nM for BAZ2A and IC50 of 180 nM for BAZ2B. It demonstrates 15-fold selectivity for binding BAZ2A/B over CECR2 and >100-fold selectivity over all other bromodomains. Synonyms: 4-(4-(1-methyl-1H-pyrazol-4-yl)-1-(2-(1-methyl-1H-pyrazol-4-yl)ethyl)-1H-imidazol-5-yl)benzonitrile; BAZ2ICR. Grades: ≥98%. CAS No. 1665195-94-7. Molecular formula: C20H19N7. Mole weight: 357.41. | |
| Bazedoxifene acetate | Bazedoxifene acetate, also called as TSE424 or WAY-140424, is a selective nonsteroidal estrogen receptor modulator (SERM) with antiosteoporotic activity (ERα: IC50= 26 nM; ERβ= 99 nM). Uses: Bone density conservation agents. Synonyms: TSE 424; TSE-424; TSE424; WAY-140424; WAY 140424; WAY140424. Grades: 95%. CAS No. 198481-33-3. Molecular formula: C32H38N2O5. Mole weight: 530.66. | |
| BC 11 hydrobromide | BC 11 hydrobromide is a selective urokinase (uPA) inhibitor (IC50 = 8.2 μM) with no activity at 8 other related enzymes. BC 11 inhibits clot lysis displaying no effect on clot formation. It also decreases viability of MDA-MB231 breast cancer cells in vitro. Synonyms: BC11 hydrobromide; BC-11 hydrobromide; BC 11 hydrobromide; BC-11 HBr Carbamimidothioic acid (4-boronophenyl)methyl ester hydrobromide; [4- (carbamimidoylsulfanylmethyl) phenyl]boronic acid hydrobromide. CAS No. 443776-49-6. Molecular formula: C8H11BN2O2S.HBr. Mole weight: 290.97. | |
| BC-1215 | BC-1215 is an inhibitor of F-box protein 3 (FBXO3) with an IC50 of 0.9 μg/mL for IL-1β release. It acts by antagonizing Fbxo3 in TRAF cell signaling and displays a low IC50 in vitro. BC-1215 can be used for inflammation research. Synonyms: N1,N2-bis[[4-(2-pyridinyl)phenyl]methyl]-1,2-ethanediamine. Grades: ≥98%. CAS No. 1507370-20-8. Molecular formula: C26H26N4. Mole weight: 394.51. | |
| BCATc Inhibitor 2 | BCATc Inhibitor 2 is a sulfonyl hydrazide that inhibits BCATc with IC50s of 0.81 for human and IC50 s of 0.2 μM for rat. It is 15-fold selectivity over BCATm. It has also been used to block calcium influx into neurons with IC50 of 4.8 μM following inhibition of glutamate uptake and to demonstrate neuroprotective efficacy in an in vivo rat model of neurodegeneration. Synonyms: Cytosolic Branched-Chain Amino Acid Transferase Inhibitor 2. Grades: ≥98%. CAS No. 406191-34-2. Molecular formula: C16H10ClF3N2O4S. Mole weight: 418.8. | |
| BCH | BCH is an inhibitor of L-type amino acid transporter (LAT1), which is a therapeutic target for human esophageal squamous cell carcinoma. BCH inhibits growth and induces apoptosis via activation of caspases in KB, Saos2 and C6 cancer cell lines. Synonyms: 2-Aminobicyclo[2.2.1]heptane-2-carboxylic acid. CAS No. 20448-79-7. Molecular formula: C8H13NO2. Mole weight: 155.2. | |
| BCI | BCI is an allosteric inhibitor of dual-specificity phosphatases (DUSP). BCI treatment of DUSP6-Myc-transfected cells suppresses DUSP6 or DUSP1 activity. BCI induces expansion of myocardial progenitors that ultimately increases heart size in zebrafish embryos via inhibiting DUSP6. BCI also inhibits lung cancer and uveal melanoma cells viability (IC50 = 0.1 to 90 μM). DUSP6 functions a feedback regulator of fibroblast growth factor (FGF) signaling to limit the activity of extracellular signal-regulated kinases (ERKs) 1 and 2. Synonyms: (E)-2-benzylidene-3-(cyclohexylamino)-2,3-dihydro-1H-inden-1-one; (2E)-2-Benzylidene-3-(cyclohexylamino)-1-indanone. Grades: 99%. CAS No. 1245792-51-1. Molecular formula: C22H23NO. Mole weight: 317.42. | |
| BCI hydrochloride | BCI hydrochloride is an allosteric inhibitor of Dusp6, acting within the phosphatase domain to prevent the catalytic stimulation of phosphatase activity induced by ERK2 substrate binding. BCI also inhibits lung cancer and uveal melanoma cells viability (IC50 values ranging from 0.1 to 90 μM). It prevents pERK2 dephosphorylation induced by Dusp6 in vitro. It is selective for Dusp6 and Dusp1 over Dusp3/VHR, Cdc25B, and PTP1B, for which it has no activity. Synonyms: 2-Benzylidene-3-(cyclohexylamino)-2,3-dihydro-1H-inden-1-one hydrochloride. Grades: ≥95%. CAS No. 95130-23-7. Molecular formula: C22H23NO·HCl. Mole weight: 353.9. | |
| BDY FL, SE | BODIPY dyes are used to generate fluorescent conjugates of proteins, nucleotides, oligonucleotides and dextrans, as well as to prepare fluorescent enzyme substrates, fatty acids, phospholipids, lipopolysaccharides, receptor ligands and polystyrene microspheres. Synonyms: 3-(3-((2,5-dioxopyrrolidin-1-yl)oxy)-3-oxopropyl)-5,5-difluoro-7,9-dimethyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide; 7-(3-((2,5-Dioxopyrrolidin-1-yl)oxy)-3-oxopropyl)-5,5-difluoro-1,3-dimethyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide; 4,4-Difluoro-5,7-Dimethyl-4-Bora-3a,4a-Diaza-s-Indacene-3-Propionic Acid, Succinimidyl Ester; BDP FL NHS ester. Grades: NMR 1H, HPLC-MS (95+%). CAS No. 146616-66-2. Molecular formula: C18H18BF2N3O4. Mole weight: 389.166. | |
| BEC | BEC, also known as S-(2-boronoethyl)-L-cysteine, is a slow-binding competitive inhibitor of recombinant rat liver arginase I with Ki values of 0.4-0.6 μM from kinetic analyses. It significantly enhances NO-dependent relaxation of human penile corpus canvernosum smooth muscle in vitro at concentrations between 0.1-1.0 mM. BEC does not inhibit NO synthase, and effectively prevented ACh tolerance in aortic and mesenteric artery preparations. Synonyms: S-(2-boronoethyl)-L-cysteine. Grades: ≥98%. CAS No. 63107-40-4. Molecular formula: C5H12BNO4S. Mole weight: 193. | |
| Beclamide | Beclamide is a chlorinated benzylpropanamide that possesses anticonvulsant activity, has been used for the treatment of tonic-clonic seizyres and has sedative properties. Uses: Anticonvulsan. Synonyms: N-Benzyl-3-chloropropionamide; N-benzyl-3-chloropropanamide. Grades: ≥98%. CAS No. 501-68-8. Molecular formula: C10H12ClNO. Mole weight: 197.66. | |
| Belcesiran | Belcesiran is an alpha-1-antitrypsin synthesis reducer. Synonyms: Dcr-a1at; all-P-ambo-2'-O-methyl-P-thioadenylyl-(3'?5')-2'-O-methyladenylyl-(3'?5')-2'-deoxy-2'-fluoroadenylyl-(3'?5')-2'-O-methylcytidylyl-(3'?5')-2'-O-methylcytidylyl-(3'?5')-2'-O-methylcytidylyl-(3'?5')-2'-O-methyluridylyl-(3'?5')-2'-deoxy-2'-fluorouridylyl-(3'?5')-2'-deoxy-2'-fluorouridylyl-(3'?5')-2'-deoxy-2'-fluoroguanylyl-(3'?5')-2'-O-methyluridylyl-(3'?5')-2'- deoxy-2'-fluorocytidylyl-(3'?5')-2'-deoxy-2'-fluorouridylyl-(3'?5')-2'-O-methyluridylyl-(3'?5')-2'-O-methylcytidylyl- (3'?5') -2'-O-methyluridylyl- (3'?5') -2'-deoxy-2'-fluorouridylyl- (3'?5') -2'-O-methyladenylyl- (3'?5') -2'-O-methyladenylyl- (3'?5') -2'-O-methyladenylyl- (3'?5') -2'-O-methylguanylyl- (3'?5') -2'-O-methylcytidylyl- (3'?5') -2'-O-methyladenylyl- (3'?5') -2'-O-methylguanylyl- (3'?5') -2'-O-methylcytidylyl- (3'?5') -2'-O-methylcytidylyl- (3'?5') -2'-O-{[2- (2-{5-[ (2-acetamido-2-deoxy-β -D-galactopyranosyl) oxy]pentan-amido}ethoxy) ethoxy]methyl}guanylyl- (3'?5') -2'-O-{[2- (2-{5-[ (2-acetamido-2-deoxy-β -D-. CAS No. 2375562-54-0. Molecular formula: C666H877F15N231O417P57S6. Mole weight: 21033.47. | |
| Belinostat | Belinostat is a hydroxamic acid-type histone deacetylase (HDAC) inhibitor. Belinostat targets HDAC enzymes to inhibit tumor cell proliferation and angiogenesis, induce apoptosis and promote cellular differentiation. Uses: Antineoplastic agents. Synonyms: Belinostat; PXD 101; Beleodaq; PDX101; PX 105684; PXD-101; PXD101; (E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2-enamide. CAS No. 414864-00-9. Molecular formula: C15H14N2O4S. Mole weight: 318.347. | |
| Belnacasan | Belnacasan is a potent and selective inhibitor of caspase-1 with Ki of 0.8 nM. Belnacasan inhibits interlukin-1β biosynthesis. Synonyms: VX 765, VX765, VX-765, Belnacasan; (2S)-1-[(2S)-2-[(4-amino-3-chlorobenzoyl)amino]-3,3-dimethylbutanoyl]-N-[(2R,3S)-2-ethoxy-5-oxooxolan-3-yl]pyrrolidine-2-carboxamide. Grades: ≥98%. CAS No. 273404-37-8. Molecular formula: C24H33ClN4O6. Mole weight: 509. | |
| Bendamustine | Bendamustine, a lbenzimidazol derivative, has been found to be an alkylating agent that acts through restraining DNA synthesis so that could be useful as an antineoplastic agent. Uses: Antineoplastic; bendamustine hydrochloride. Synonyms: 5-(Bis(2-chloroethyl)amino)-1-methyl-2-benzimidazolebutyric acid;5-[Bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid;Bendamustine. Grades: 98%. CAS No. 16506-27-7. Molecular formula: C16H21Cl2N3O2. Mole weight: 358.26. | |
| Bendamustine Chloro Dimer Impurity | Bendamustine Chloro Dimer Impurity is an impurity of Bendamustine, a chemotherapy medication indicated for the treatment of chronic lymphocytic leukemia, multiple myeloma, and non-Hodgkin's lymphoma. Synonyms: Bendamustine Dimer Impurity; 5-[bis(2-Chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic Acid 2-[[2-(3-Carboxypropyl)-1-methyl-1H-benzimidazol-5-yl](2-chloroethyl)amino]ethyl Ester. Grades: > 95%. CAS No. 1228551-91-4. Molecular formula: C32H41Cl3N6O4. Mole weight: 680.08. | |
| Benoxafos | insecticide. Synonyms: Benoxafos. Grades: >98%. CAS No. 16759-59-4. Molecular formula: C12H14Cl2NO3PS2. Mole weight: 386.25. | |
| Benserazide HCl | Cas No. 14919-77-8. | |
| Benzamide, N-[4-methyl-3-[[4-(6-methyl-3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-4-[(4-methyl-1-piperazinyl)methyl]- | This product is a kinase inhibitor used in the treatment of certain types of cancer, including non-small cell lung cancer and pancreatic cancer. It works by inhibiting specific enzymes involved in cell growth and proliferation, ultimately leading to tumor regression. Synonyms: N-[4-methyl-3-[[4-(6-methylpyridin-3-yl)pyrimidin-2-yl]amino]phenyl]-4-[(4-methylpiperazin-1-yl)methyl]benzamide; CHEMBL1079113; 1032314-85-4; SCHEMBL11939618; BDBM50313640; ZINC49018631. Grades: 95%. CAS No. 1032314-85-4. Molecular formula: C30H33N7O. Mole weight: 507.63. | |
| Benzamidine hydrochloride | Benzamidine is a reversible inhibitor of serine proteases, including trypsin, plasmin, and thrombin (Kis = 35, 350, and 220 μM, respectively). Benzamidine inhibits the autoactivation of human blood coagulation factor VII, useful as a tool for studying the interactions between this and other relevant growth factors. Uses: Serine proteinase inhibitors. Synonyms: Benzenecarboximidamide, hydrochloride (1:1); Benzamidine, monohydrochloride; Benzenecarboximidamide, monohydrochloride; Amidinobenzene hydrochloride; Benzamidinium chloride; Benzimidamide hydrochloride. Grades: ≥98%. CAS No. 1670-14-0. Molecular formula: C7H8N2.HCl. Mole weight: 156.61. | |
| Benzcyclane | Benzcyclane, also called as Bencyclane or Benzcyclan, is a platelet aggregation inhibitor and used as a vasodilator effective. Uses: Calcium channel blockers. Synonyms: BENCYCLANE; benzcyclane; 2179-37-5; Bencyclane [INN]; Bencyclane; Benzcyclan; 3-(1-benzylcycloheptyl)oxy-N,N-dimethylpropan-1-amine; Benzcyclan; DTXSID0022646; Bencyclane (INN); 3-((1-Benzylcycloheptyl)oxy)-N,N-dimethylpropylamin; 6I97Z6S135; 1-Propanamine, N,N-dimethyl-3-((1-(phenylmethyl)cycloheptyl)oxy)-; Bencyclanum [INN-Latin]; 3-[(1-Benzylcycloheptyl)oxy]-N,N-dimethylpropylamine; Benciclano [INN-Spanish]; Benciclano; Bencyclanum; Bencyclan; 3-((1-BENZYLCYCLOHEPTYL)OXY)-N,N-DIMETHYLPROPYLAMINE; 1-Propanamine, N,N-dimethyl-3-[[1-(phenylmethyl)cycloheptyl]oxy]-; EINECS 218-547-0; BENCYCLANE [MI]; BENCYCLANE [WHO-DD]; SCHEMBL64881; DTXCID002646; CHEMBL2110767; UNII-6I97Z6S135; CHEBI:135205; FYJJXENSONZJRG-UHFFFAOYSA-N; Tox21_113690; HY-U00134; AKOS040732567; CS-7171; DB13488; NCGC00249914-01; CAS-2179-37-5; D07500; Q723117; N-(3-[(1-Benzylcycloheptyl)oxy]propyl)-N,N-dimethylamine #; N,N-dimethyl-3-{[1-(phenylmethyl)cycloheptyl]oxy}propan-1-amine. CAS No. 2179-37-5. Molecular formula: C19H31NO. Mole weight: 289.46. | |
| Benzo[ghi]perylene | Benzo[ghi]perylene is an environmental pollutant. Uses: An n-channel organic semiconductor. Synonyms: hexacyclo[12.8.0.02, 11.03, 8.04, 21.017, 22]docosa-1(14), 2(11), 3(8), 4, 6, 9, 12, 15, 17(22), 18, 20-undecaene. Grades: 95 %. CAS No. 191-24-2. Molecular formula: C22H12. Mole weight: 276.33. | |
| Benzoic acid, 2-(3-methyl-1-oxobutyl)- | Benzoic acid, 2-(3-methyl-1-oxobutyl)- is an impurity of Butylphthalide, an anti-cerebral-ischemia drug. Synonyms: 2-(3-methylbutanoyl)benzoic acid. CAS No. 152567-80-1. Molecular formula: C12H14O3. Mole weight: 206.241. | |
| Benzoylhypacoitine | Benzoylhypacoitine is extracted from the roots of Aconitum carmichaeli Debx. It might be the principal active components which affect mitochondrial growth by Fuzi and its processed products. Uses: Might be the principal active components which affect mitochondrial growth by fuzi and its processed products. Synonyms: Benzoylhypaconine; Deacetylhypaconitine. Grades: >98%. CAS No. 63238-66-4. Molecular formula: C31H43NO9. Mole weight: 573.68. | |
| Benzoylmesaconine | Benzoylmesaconine is the most abundant component of Wutou decoction, which is widely used in China because of its therapeutic effect on rheumatoid arthritis. Synonyms: Mesaconine 14-benzoate. Grades: >98%. CAS No. 63238-67-5. Molecular formula: C31H43NO10. Mole weight: 589.67. | |
| Benzoylmesaconine-7-Palmitate | Benzoylmesaconine-7-Palmitate is an alkaloid isolated from aconitum carmichaeli Debx. Benzoylmesaconine has powerful antinociceptive, antiarrhythmic and properties due to their ability to blockade voltage-dependent sodium channels, but has less toxic monoesters than aconitine and mesaconitine. Grades: > 98%. Molecular formula: C47H73NO11. Mole weight: 828.08. | |
| Benzyl 2,3,4-Tri-O-benzyl-α-D-glucopyranoside | Benzyl 2,3,4-Tri-O-benzyl-α-D-glucopyranoside, a widely employed compound within the biomedical sector, showcases a plethora of pharmacological attributes, rendering it efficacious in addressing select illnesses. Researchers fervently investigate this exceptional specimen's capacity to engender curative medications targeting distinct pathways linked to metabolic infirmities and contagions. Synonyms: Benzyl 2,3,4-Tri-O-benzyl-|A-D-glucopyranoside; Benzyl 2-O,3-O,4-O-tribenzyl-alpha-D-glucopyranoside. Grades: 98%. CAS No. 59935-49-8. Molecular formula: C34H36O6. Mole weight: 540.6. | |
| Benzyl (4-hydroxyphenyl)carbamate | Benzyl (4-hydroxyphenyl)carbamate, a crucial pharmaceutical intermediate, synergizes diverse drug synthesis. Capable of potentiating anti-neoplastic responses in conjunction with antioxidant activities, this molecular entity encapsulates immense therapeutic potential. Notably, investigations are underway to examine its efficacy as a prospective therapeutic agent for neurodegenerative conditions including Alzheimer's and Parkinson's diseases. Synonyms: 4-(benzyloxycarbonylamino)phenol; (4-hydroxy-phenyl)-carbamic acid benzyl ester. CAS No. 7107-59-7. Molecular formula: C14H13NO3. Mole weight: 243.26. | |
| Bepotastine Besylate | Bepotastine is a histamine H1 receptor antagonist. Bepotastine has been approved in Japan for the treatment of allergic rhinitis and uriticaria/puritus. Synonyms: Bepotastine besylate; Bepreve; Betotastine besilate; Talion; 4-[(S)-(4-chlorophenyl)-2-pyridinylmethoxy]-1-piperidinebutanoic acid, monobenzenesulfonate. Grades: >98%. CAS No. 190786-44-8. Molecular formula: C27H31ClN2O6S. Mole weight: 547.063. | |
| Berbamine Hydrochloride | Berbamine is a calcium channel blocker which is isolated from the roots of Cocculus orbiculatus (L.) DC. It can block the calcium-induced contraction of depolarized pig coronary artery strips. It was indicated that Berbamine hydrochloride may competitively antagonize the action of calcium. Synonyms: 6,6',7-trimethoxy-2,2'-dimethylberbaman-12-ol dihydrochloride. Grades: >98%. CAS No. 6078-17-7. Molecular formula: C37H42Cl2N2O6. Mole weight: 681.65. | |
| Berberine chloride hydrate | The plant-based alkaloid berberine has potential therapeutic applications for breast cancer, although a better understanding of the genes and cellular pathways regulated by this compound is needed to define the mechanism of its action in cancer treatment. In this review, the molecular targets of berberine in various cancers, particularly breast cancer, are discussed. Berberine was shown to be effective in inhibiting cell proliferation and promoting apoptosis in various cancerous cells. Some signaling pathways affected by berberine, including the MAP (mitogen-activated protein) kinase and Wnt/β-catenin pathways, are critical for reducing cellular migration and sensitivity to various growth factors. Treatment with BBR(Berberine) in rats on the atherogenic diet reduced plasma total cholesterol and nonHDL cholesterol levels by 29%-33% and 31%-41%, respectively, with no significant differences being observed among the three doses. Berberine induced both apoptotic and autophagic death of HepG2 cells, which was associated with a significant activation of AMPK and an increased expression of the inactive form of acetyl-CoA carboxylase (ACC). Berberine did not show major effects on viability of HEK-293 embryonic kidney and HCT116 colon carcinoma cells and was not toxic in concentrations up to 20 μM. Berberine inhibited β-catenin transcriptional activity and attenuated anchorage-independent growth. As a result of berberine treatment, cellular levels of active β-catenin were reduced concomitant with an increase in the expression of E-cadherin. Synonyms: Natural Yellow 18. Grades: >98%. CAS No. 141433-60-5. Molecular formula: C20H18ClNO4. Mole weight: 371.81. | |
| Berberine hydrochloride | Berberine hydrochloride is an isoqinoline alkaloid and acts as a COX-2 inhibitor that exhibits chemopreventive activity against colon tumor formation. Study in humans and hamsters shows that berberine reduces total cholesterol, low-density lipoprotein (LDL) cholesterol, and triglycerides. It also inhibits c-Jun and suppresses inflammation and cancers. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: Berberine chloride; Natural Yellow 18; Benzodioxide; Berberinium chloride. Grades: ≥ 98%. CAS No. 633-65-8. Molecular formula: C20H18ClNO4. Mole weight: 371.817. | |
| Bernardioside A | Bernardioside A is a triterpenoid saponin found in the Bellis perennis. Synonyms: 3-O-beta-D-Glucopyranosyl polygalacic acid; Polygalacic acid 3-O-beta-D-glucopyranoside. Grades: >98%. CAS No. 121368-52-3. Molecular formula: C36H58O11. Mole weight: 666.849. | |
| Besifovir | Besifovir is an orally available phosphonate nucleotide for the potential treatment of hepatitis B virus infection was well tolerated and also had a good clinical safety profile. Uses: Dna-directed dna polymerase inhibitors; hepatitis b virus replication inhibitors. Synonyms: LB 80380; LB80380; LB-80380; (1- ( (2-Amino-9H-purin-9-yl) methyl) cyclopropoxy) methylphosphonic acid;P-[[[1-[(2-amino-9H-purin-9-yl)methyl]cyclopropyl]oxy]methyl]-phosphonic acid. Grades: ≥98%. CAS No. 441785-25-7. Molecular formula: C10H14N5O4P. Mole weight: 299.22. | |
| Bestatin | Bestatin is a specific aminopeptidase B inhibitor produced by Streptomyces olivoreticuli. Bestatin is a potent aminopeptidase-B and leukotriene (LT) A4 hydrolase inhibitor used in the treatment of acute myelocytic leukemia. It exhibits potential immunomodulatory and antitumor activities. Uses: The treatment of acute myelocytic leukemia. Synonyms: Ubenimex. Grades: >98%. CAS No. 58970-76-6. Molecular formula: C16H24N2O4. Mole weight: 308.37. | |
| β-Amyloid (1-40) | Amyloid β-Peptide (1-40) (human) is a 40-residue protein fragment of the C-terminal portion of the β-amyloid protein, which is found in plaques in the brains of patients with Alzheimer's disease. It is neurotrophic and neurotoxic in vivo and in vitro in human and rat neuronal cell cultures. It prevented neuronal cell death by inhibiting fibril formation when administered concurrently with Aβ (1-42) in rat cortical cultures at 3 μM. It prevented neuronal damage when injected into rat entorhinal cortex with Aβ (1-42) both at 400 μM. Synonyms: Amyloid β Protein Fragment 1-40; Aβ40. Grades: 95%. CAS No. 131438-79-4. Molecular formula: C194H295N53O58S. Mole weight: 4329.8599999999997. | |
| β-ANGELICA LACTONE | Synonyms: BETA-ANGELICA LACTONE; 2-Penten-4-olide; 2-Pentenoic acid, 4-hydroxy-, gamma-lactone; 4-hydroxy-2-pentanoicacigamma-lactone; 4-Hydroxy-2-pentenoic acid gamma-lactone; 4-hydroxy-2-pentenoicacidgamma-lactone. Grades: 95%. CAS No. 591-11-7. Molecular formula: C5H6O2. Mole weight: 98.1. | |
| β-Apo-13-carotenone | β-Apo-13-carotenone, also known as D'Orenone, a naturally occurring β-apocarotenoid, is an antagonist of RXR&alpha. Synonyms: (3E,5E,7E)-6-methyl-8-(2,6,6-trimethylcyclohexen-1-yl)octa-3,5,7-trien-2-one; beta-apo-13-carotenone. CAS No. 17974-57-1. Molecular formula: C18H26O. Mole weight: 258.4. | |
| β-Apo-13-carotenone D3 | The deuterium labeled β-Apo-13-carotenone which is an antagonist of RXR&alpha. Synonyms: 3,?5,?7-Octatrien-2-one-1,?1,?1-d3, 6-methyl-8-(2,?6,?6-trimethyl-1-cyclohexen-1-yl)?-, (E,?E,?E)?- (9CI). CAS No. 86530-28-1. Molecular formula: C18H23D3O. Mole weight: 261.42. | |
| βARK1 Inhibitor | βARK1 inhibitor is an inhibitor of G protein-coupled receptor kinase 2/β-adrenergic receptor kinase 1 (GRK2/βARK1) with IC50 value of 126 μM. It has been shown to decrease systolic blood pressure in ob/ob and nicotinamide plus streptozotocin-induced mouse models of type 2 diabetes when administered at a dose of 200 μg/kg. Synonyms: betaARK1 Inhibitor; Methyl 5-[2-(5-nitro-2-furyl)vinyl]-2-furoate; GRK2 Inhibitor. Grades: ≥95% (mixture of isomers). CAS No. 24269-96-3. Molecular formula: C12H9NO6. Mole weight: 263.2. | |
| β-chamigrenic acid | β-Chamigrenic acid is an extensively utilized natural compound used in studying inflammatory ailments like rheumatoid and arthritand inflammatory bowel disease. Synonyms: Spiro[5.5]?undec-2-ene-3-carboxylic acid, 7,?7-dimethyl-11-methylene-, (6S)?-. Grades: >98%. CAS No. 74042-14-1. Molecular formula: C15 H22 O2. Mole weight: 234.33. | |
| β-Cyclodextrin | β-cyclodextrin is a cyclic oligosaccharide produced from starch via enzymatic conversion. It is widely used in food, medicine, cosmetics, chemical and other industries. β-cyclodextrin is used as a complexing agent in drug delivery, increasing the water solubility, dissolution rate and bioavailability of poorly water-soluble drugs. β-Cyclodextrin is commonly used to produce HPLC columns that allow the separation of chiral enantiomers. Uses: Sequestering agents. Synonyms: Cycloheptaamylose; Adrabetadex; BCD; Betadex; BW 7 (polysaccharide); Cavamax W 7; Celdex N; Cibatex OC-CLD; Cyclodextrin Beta W 7M1.8; Cycloheptaglucan; Cycloheptaglucosan; Cyclomaltoheptaose; CYL 3190; Dexipar β-100; Dextrin, β-cyclo; Dexy Pearl 100; HP-β-CD; HRBS-Q 009; Kleptose; Kleptose B; Kleptose STD; NSC 269471; NSC 314334; Rhodocap N; Rindex B; Ringdex B; Ringdex BL; Schardinger β-dextrin; Stereoisomer of 5, 10, 15, 20, 25, 30, 35-heptakis(hydroxymethyl)-2, 4, 7, 9, 12, 14, 17, 19, 22, 24, 27, 29, 32, 34-tetradecaoxaoctacyclo[31.2.2.23, 6.28, 11.213, 16.218, 21.223, 26.228, 31]nonatetracontane-36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49-tetradecol; Trappsol Cyclo; VAR 200; VTS 270; β-Cycloamylose; β-Cycloheptaamylose; β-Dextrin. Grades: ≥95%. CAS No. 7585-39-9. Molecular formula: C42H70O35. Mole weight: 1134.98. | |
| β-D-Glucopyranoside, (3β, 6α, 16β, 20R, 24S)-3-[(3, 4-di-O-acetyl-β-D-xylopyranosyl)oxy]-20, 24-epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl | β-D-Glucopyranoside, (3β, 6α, 16β, 20R, 24S)-3-[(3, 4-di-O-acetyl-β-D-xylopyranosyl)oxy]-20, 24-epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl is extracted from roots of Astragalus membranaceus (Fisch.) Bunge. Synonyms: 3-O-3',4'-Diacetyl-beta-D-xylopyranosyl-6-O-beta-D-glucopyranosyl-cycloastragenol. Grades: >98%. CAS No. 1324005-51-7. Molecular formula: C45H72O16. Mole weight: 869. | |
| (+)-β-Dihydrotetrabenazine | (+)-β-Dihydrotetrabenazine is a potent inhibitor of vascular monoamine transporter 2 (VMAT2) and an agent of significant interest for therapeutic and molecular imaging applications. Synonyms: (2S,3R,11bR)-1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-ol; (2S,3R,11bR)-Dihydrotetrabe; Tetrabenazine Related Impurity 6(2S,3R,11bR). Grades: ≥95%. CAS No. 924854-60-4. Molecular formula: C19H29NO3. Mole weight: 319.44. | |
| β-Elemene | β-Elemene is a sesquiterpene compound found in C. sativa. It exhibits antineoplastic, antioxidant and antimicrobial properties. Synonyms: beta-Elemen; (-)-beta-Elemene; Levo-beta-elemene; (1S,2S,4R)-1-ethenyl-1-methyl-2,4-bis(prop-1-en-2-yl)cyclohexane. CAS No. 515-13-9. Molecular formula: C15H24. Mole weight: 204.35. | |
| β-Endorphin (bovine, camel, mouse) | β-Endorphin is an endogenous opioid neuropeptide. Uses: Neurotransmitter agents. Synonyms: beta-Endorphin (bovine, camel, mouse); beta-Endorphin (1-31); H-Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-His-Lys-Lys-Gly-Gln-OH. Grades: ≥98%. CAS No. 59887-17-1. Molecular formula: C155H250N42O44S. Mole weight: 3437.96. | |
| β-Endorphin (equine) | β-Endorphin is an endogenous opioid neuropeptide which has analgesic properties. Synonyms: beta-Endorphin (equine); H-Tyr-Gly-Gly-Phe-Met-Ser-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-His-Lys-Lys-Gly-Gln-OH. Grades: ≥98% by HPLC. CAS No. 79495-86-6. Molecular formula: C154H248N42O44S. Mole weight: 3423.94. | |
| (beta)-Estradiol 17-acetate | β-Estradiol 17-acetate is a metabolite of estradiol. Synonyms: 1,3,5(10)-Estratriene-3,17β-diol 17-acetate. Grades: >98%. CAS No. 1743-60-8. Molecular formula: C20H26O3. Mole weight: 314.42. | |
| β-Eudesmol | β-Eudesmol is a sesquiterpene found in a wide range of plants, including Cannabis, and has diverse biological activities. It acts as a non-competitive antagonist of nicotinic acetylcholine receptors (nAChRs). Synonyms: (+)-β-Eudesmol; beta-Eudesmol. Grades: ≥95%. CAS No. 473-15-4. Molecular formula: C15H26O. Mole weight: 222.37. | |
| β-Glycerophosphate sodium salt hydrate | β-Glycerophosphate is a protein phosphatase inhibitor that can be used as a phosphate group donor in matrix mineralization studies. Synonyms: Sodium 2-glycerophosphate pentahydrate; Sodium 1,3-dihydroxypropan-2-yl phosphate pentahydrate. Grades: ≥95%. CAS No. 13408-09-8. Molecular formula: C3H7O6P·2Na·5H2O. Mole weight: 306.1. | |
| Betahistine EP Impurity C | Betahistine EP Impurity C is structurally related to Betahistine and is a dimer of Betahistine. It is used as a reagent in the preparation of copper pyridylmethylethylenediamine dicyanamido polymeric complexes. Synonyms: Methylbis(2-pyridylethyl)amine; N-Methyl-N,N-bis(2-pyridylethyl)amine; NSC 19005. Grades: 98%. CAS No. 5452-87-9. Molecular formula: C15H19N3. Mole weight: 241.338. | |
| Beta-(-)-Hydrastine | Hydrastine is a natural alkaloid which is present in Hydrastis canadensis and other plants of the ranunculaceae family. Synonyms: (1R,9S)-(-)-beta-Hydrastine;Hydrastine base. Grades: 97 % (HPLC). CAS No. 118-08-1. Molecular formula: C21H21NO6. Mole weight: 383.39. | |
| Betaine hydrochloride | Betaine, which is isolated from the roots of Beta vulgaris, has been shown to protect internal organs, improve vascular risk factors, and enhance performance. Databases of betaine content in food are being developed for correlation with population health studies. The growing body of evidence shows that betaine is an important nutrient for the prevention of chronic disease. Administration of Betaine inhibited inflammatory cytokines such as TNF-α, IL-6, iNOS and COX-2. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: (carboxymethyl)trimethyl-ammoniuchloride; 1-carboxy-n,n,n-trimethyl-methanaminiuchloride; Achylin; Acidin; Acidine; Acidogeno; acidolhydrochloride; Acidol-Pepsin. Grades: >98%. CAS No. 590-46-5. Molecular formula: C5H12ClNO2. Mole weight: 153.6. | |
| β-Lapachone | β-Lapachone is a naturally occurring quinone obtained from the bark of the lapacho tree (Tabebuia avellanedae), exhibiting anti-inflammatory properties by suppressing the NF-κB activation by blocking IκBα degradation and downregulating the ERK, p38 mitogen-activated protein kinase and Akt pathway. Synonyms: ARQ501, ARQ 501, ARQ-501, beta lapachone; BETA-LAPACHONE; 3,4-DIHYDRO-2,2-DIMETHYL-2H-NAPHTHO[1,2-B]PYRAN-5,6-DIONE; 3,4-DIHYDRO-2,2-DIMETHYL-2H-NAPHTHOL[1,2-B]PYRAN-5,6-DIONE; 2-b)pyran-5,6-dione,3,4-dihydro-2,2-dimethyl-2h-naphtho(; b-Lapachone; B-LAPACHONE,2,2-DIMETHYL-3,4-DIHYDRO-2H-BENZO[H]CHROME. Grades: > 98%. CAS No. 4707-32-8. Molecular formula: C15H14O3. Mole weight: 242.27. | |
| Betamethasone EP Impurity D | Betamethasone EP Impurity D is an intrinsic impurity present in the pharmaceutical drug Betamethasone. Betamethasone serves a multitude of purposes, particularly catering to the therapy of inflammatory cutaneous ailments encompassing eczema and psoriasis. Synonyms: Betamethasone 21-(ethyl carbonate); Betamethasone, 21-(ethyl carbonate); UNII-26764AL880; 26764AL880; Betamethasone EP Impurity D; ethyl [2-[(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] carbonate; DTXSID10200599; Betamethasone 21-O-Ethyl Carbonate; BETAMETHASONE IMPURITY D [EP IMPURITY]; Q27254059; 9-FLUORO-11.BETA.,17-DIHYDROXY-16.BETA.-METHYL-3,20-DIOXOPREGNA-1,4-DIEN-21-YL ETHOXYCARBOXYLATE; PREGNA-1,4-DIENE-3,20-DIONE, 21-((ETHOXYCARBONYL)OXY)-9-FLUORO-11,17-DIHYDROXY-16-METHYL-, (11.BETA.,16.BETA.)-. Grades: > 95%. CAS No. 52619-05-3. Molecular formula: C25H33FO7. Mole weight: 464.54. | |
| β-NADPH tetra (cyclohexylammonium) salt | β-NADPH tetra(cyclohexylammonium), generating in vivio by the pentose phosphate pathway, is a a ubiquitous cofactor and biological reducing agent. Uses: β-nadph tetra(cyclohexylammonium) is a ubiquitous cofactor and biological reducing agent. Synonyms: β-NADPH, NADPH, TPNH, Triphosphopyridine nucleotide, reduced form. Grades: ≥95%. CAS No. 100929-71-3. Molecular formula: C21H30N7O17P3·4C6H13N. Mole weight: 1142.12. | |
| β-Nicotinamide Mononucleotide | β-Nicotinamide mononucleotide, a major product of extracellular NAMPT reaction, could ameliorate glucose intolerance and also increase hepatic insulin sensitivity and sorts of gene expression involved in inflammatory response, oxidative stress and so on. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: Nicotinamide Mononucleotide; NMN; β-NMN; β-Nicotinamide mononucleotide; BETA-NMN;BETA-NICOTINAMIDE MONONUCLEOTIDE;BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE;NMN;NICOTINAMIDE-1-IUM-1-BETA-D-RIBOFURANOSIDE 5'-PHOSPHATE;NICOTINAMIDE RIBOTIDE;NICOTINAMIDE MONONUCLEOTIDE;3-(aminocarbonyl)-1-(5-O-phosphonato-beta-D-ribofuranosyl)pyrid. Grades: ≥95%. CAS No. 1094-61-7. Molecular formula: C11H15N2O8P. Mole weight: 334.22. | |
| Bethanidine Sulfate | This active molecular is a guanidinium antihypertensive agent through adrenergic neuron-blocking. Uses: Betanidine is an adrenergic neuron-blocking drug. Synonyms: N,N'-Dimethyl-N''-(phenylmethyl)-guanidine Sulfate; 1-Benzyl-2,3-dimethyl-guanidine sulfate; 1-Benzyl-2,3-dimethylguanidine Sulfate; 1-Benzyl-2,3-dimethylguanidinium Sulfate; BW 467C60; Batel; Bendogen; Benzaidin; Benzanidin; Benzanidine; Betanidol; Betanidole; Bethanid; Bethanidine hemisulfate; Esbatal; Eusmanid; Hypersin; NSC 106563; Regulin; Tenathan, 55-73-2 free amine. Grades: 98%. CAS No. 114-85-2. Molecular formula: C20H32N6O4S. Mole weight: 452.57. | |
| Bethoxazin | Bethoxazin(Bethoguard) is a new broad spectrum industrial microbicide with applications in material and coating preservation. Synonyms: Bethogard; Bethoguard. Grades: >98%. CAS No. 163269-30-5. Molecular formula: C11H9NO2S2. Mole weight: 251.32. | |
| Betrixaban | A direct factor Xa inhibitor used as an oral anticoagulant drug. It has been prescribed as a venous thromboembolism (VTE) prophylactic for adult patients with moderate to severe restricted motility or with other risks for VTE. Uses: Factor xa inhibitors. Synonyms: PRT054021; PRT 054021; PRT-054021; MK-4448; MK 4448; MK4448; PRT-021; PRT 021; PRT021; MLN-1021; MLN 1021; MLN1021; Bevyxxa; N-(5-chloropyridin-2-yl)-2-[[4-(N,N-dimethylcarbamimidoyl)benzoyl]amino]-5-methoxybenzamide. CAS No. 330942-05-7. Molecular formula: C23H22ClN5O3. Mole weight: 451.91. | |
| Betulaprenol-7 | A polyprenyl alcohol with tumor cytotoxic activity. Uses: A polyprenyl alcohol with tumor cytotoxic activity. Synonyms: all-E-Heptaprenol; Heptaprenol; Heptaprenol (all trans). Grades: 85%. CAS No. 32304-16-8. Molecular formula: C35H58O. Mole weight: 494.848. | |
| Bevirimat | Bevirimat, also known as MPC-4326 and PA-457, is an anti-HIV drug derived from a betulinic acid-like compound, first isolated from Syzygium claviflorum, a Chinese herb. It is believed to inhibit HIV by a novel mechanism, so-called maturation inhibition. Like protease inhibitors, bevirimat and other maturation inhibitors interfere with protease processing of newly translated HIV polyprotein precursor, called gag. Bevirimat prevents this viral replication by specifically inhibiting cleavage of the capsid protein (CA) from the SP1 spacer protein. Synonyms: MPC4326; MPC 4326; MPC-4326; PA457; PA 457; PA-457; FH11327; FH-11327; FH 11327; YK FH312; Bevirimat; YKFH312. Grades: >98%. CAS No. 174022-42-5. Molecular formula: C36H56O6. Mole weight: 584.83. | |
| Bevurogant | Bevurogant is a retinoid-related orphan receptor-gamma t (RORγt) antagonist. Synonyms: 8-[(1S)-1-cyclopropylethyl]-2-(4-cyclopropyl-6-methylpyrimidin-5-yl)-6-({[5-(methanesulfonyl)pyridin-2-yl]methyl}amino)pteridin-7(8H)-one; 8-((S)-1-Cyclopropyl-ethyl)-2-(4-cyclopropyl-6-methyl-pyrimidin-5-yl)-6-[(5-methanesulfonyl-pyridin-2-ylmethyl)-amino]-8H-pteridin-7-one; (S)-2-(4-cyclopropyl-6-methylpyrimidin-5-yl)-8-(1-cyclopropylethyl)-6-(((5-(methylsulfonyl)pyridin-2-yl)methyl)amino)pteridin-7(8H)-one. CAS No. 1817773-66-2. Molecular formula: C26H28N8O3S. Mole weight: 532.62. | |
| BF 738735 | A potent and selective ATP-competitive phosphatidylinositol 4-kinase III beta (PI 4-KIIIβ) inhibitor (IC50 = 5.7 nM). Displays approximately 200-fold selectivity over PI 4-KIII&alpha. Broad spectrum enterovirus replication inhibitor. Synonyms: 2-Fluoro-4-[2-methyl-8-[[[3- (methylsulfonyl) phenyl]methyl]amino]imidazo[1, 2-a]pyrazin-3-yl]phenol; BF738735; BF-738735. Grades: ≥98%. CAS No. 1436383-95-7. Molecular formula: C21H19FN4O3S. Mole weight: 426.47. | |
| BF844 | BF844 is a CLRN1N48K stabilizer that can attenuate progressive hearing loss and deafness in an Usher syndrome type III (USH3) mouse model. Uses: Hearing loss therapy. Synonyms: BioFocus 844; BioFocus844; BioFocus-844; BF844; BF-844; BF 844; 4-Chloro-α,α-dimethyl-3,5-diphenyl-1H-pyrazolo[3,4-c]pyridazine-1-ethanol. Grades: 98%. CAS No. 1404506-35-9. Molecular formula: C21H19ClN4O. Mole weight: 378.85. | |
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