BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Bromindione | Bromindione, an inandione derivative, could be used as an orally bioavaliable anticoagulant. Uses: Bromindione could be used as an orally bioavaliable anticoagulant. Synonyms: Bromindione;2-(4-Bromophenyl)-1H-indene-1,3(2H)-dione;2-(4-Bromophenyl)-2,3-dihydro-1H-indene-1,3-dione;2-(4-bromophenyl)indane-1,3-quinone;2-(4-bromophenyl)indene-1,3-dione. Grades: 95%. CAS No. 1146-98-1. Molecular formula: C15H9BrO2. Mole weight: 301.13. |  |
| Bromocriptine Mesylate | Bromocriptine mesylate is the mesylate salt of Bromocriptine. It is a dopamine receptor agonist. It is a derivative of the ergotoxin group of ergot alkaloids. Uses: Antiparkinson agents. Synonyms: 2-Bromo α-Ergocryptine Mesylate; (5'α)-2-Bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)ergotaman-3',6',18-trione Methanesulfonate; 2-Bromoergocryptine; Bagren; CB 154; Parlodel; Pravidel. Grades: 98%. CAS No. 22260-51-1. Molecular formula: C33H44BrN5O8S. Mole weight: 750.72. | |
| Bromopyruvic acid | This active molecular is a synthetic brominated derivative of pyruvic acid which is a hexokinase II inhibitor and an effective antitumor agent because it is a highly reactive alkylating agent. The acute toxicity study provided an LD50 of 191.7 mg/kg for 3-BrPA in vivo. In 2010, Preclinical trials in Cancer in USA (Intra-arterial) for bromopyruvate was approved. In 2013, US FDA approved IND application for bromopyruvate in Liver cancer. Uses: Eliminating aggressive liver tumors. Synonyms: 3-bromo-2-oxopropanoic acid. Grades: 98 %. CAS No. 1113-59-3. Molecular formula: C3H3BrO3. Mole weight: 166.96. | |
| Bropirimine | Bropirimine is an immunostimulant as well as anticancer agent and has been found to exhibit direct antitumor activity. Synonyms: 2-Amino-5-bromo-6-phenyl-4(3H)-pyrimidone. Grades: ≥96% by HPLC. CAS No. 56741-95-8. Molecular formula: C10H8BrN3O. Mole weight: 266.09. | |
| Brostallicin | Brostallicin, a-bromo-acrylamido tetra-pyrrole derivative, is a second-generation minor groove binder (MGB) structurally related to distamycin A with potential antineoplastic activity. Compared with that of other minor groove binders, this agent appears to bind covalently to DNA in a different manner and its activity does not depend on a functional DNA mismatch repair (MMR) mechanism. Synonyms: 4-[[4-[[4-[[4-(2-bromoprop-2-enoylamino)-1-methylpyrrole-2-carbonyl]amino]-1-methylpyrrole-2-carbonyl]amino]-1-methylpyrrole-2-carbonyl]amino]-N-[2-(diaminomethylideneamino)ethyl]-1-methylpyrrole-2-carboxamide; brostallicin; PNU 166196; PNU-166196; PNU166196. Grades: >98%. CAS No. 203258-60-0. Molecular formula: C30H36BrClN12O5. Mole weight: 723.58. | |
| Brotianide | Brotianide, with anti-fasciolidal activity, is an anthelminthic drug for the treatment of severe infections on animals to remove larvae. Synonyms: [2-bromo-6-[(4-bromophenyl)carbamothioyl]-4-chlorophenyl] acetate; Brotianide; Dirian; Brotianidum [INN-Latin]; Brotianida [INN-Spanish]; UNII-30OGU6XH7S; Brotianide; Dirian; BAY-VA 4059; BAY-VA-4059; BAY-VA4059. Grades: >98%. CAS No. 23233-88-7. Molecular formula: C15H10Br2ClNO2S. Mole weight: 463.568. | |
| Brusatol | Brusatol is a triterpenoid isolated from the Brucea javanica plant. Brusatol acts as an Nrf2 inhibitor with anticancer activity. Uses: Anti-tumor. Synonyms: (+)-Brusatol; Yatansin. Grades: >98%. CAS No. 14907-98-3. Molecular formula: C26H32011. Mole weight: 520.53. | |
| BT2 | BT2 is an allosteric inhibitor of branched-chain α-ketoacid dehydrogenase (BCKDC) kinase (BDK; IC50 = 3.19 μM). BT2 can dissociate BDK from BCKDC via binding to BDK. Synonyms: BT2; BT-2; BT 2; 3,6-Dichloro-1-benzothiophene-2-carboxylic acid. Grades: 99%. CAS No. 34576-94-8. Molecular formula: C9H4Cl2O2S. Mole weight: 247.1. | |
| BTSA1 | BTSA1 is a BAX activator that binds to the N-terminal activation site with high affinity and specificity induces conformational changes to BAX leading to BAX-mediated apoptosis. It effectively promotes apoptosis in leukemia cell lines and patient samples while sparing healthy cells. Synonyms: BTSA1. Grades: ≥98%. CAS No. 314761-14-3. Molecular formula: C21H14N6OS2. Mole weight: 430.51. | |
| BTZ043 | The new antitubercular drug candidate 2-[2-S-methyl-1,4-dioxa-8-azaspiro[4.5]dec-8-yl]-8-nitro-6-(trifluoromethyl)-4H-1,3-benzothiazin-4-one (BTZ043) targets the DprE1 (Rv3790) subunit of the enzyme decaprenylphosphoryl-beta-d-ribose 2'-epimerase. To monitor the potential development of benzothiazinone (BTZ) resistance, a total of 240 sensitive and multidrug-resistant Mycobacterium tuberculosis clinical isolates from four European hospitals were surveyed for the presence of mutations in the dprE1 gene and for BTZ susceptibility. All 240 strains were susceptible, thus establishing the baseline prior to the introduction of BTZ043 in clinical trials. Synonyms: BZT043; BZT 043; BZT-043; 2-[2-S-methyl-1,4-dioxa-8-azaspiro[4.5]dec-8-yl]-8-nitro-6-(trifluoromethyl)-4H-1,3-benzothiazin-4-one. CAS No. 1161233-85-7. Molecular formula: C17H16F3N3O5S. Mole weight: 431.39. | |
| BTZ-N3 | BTZ-N3, a electron deficient nitroaromatic compound, is a potent and selective anti-TB drug candidate. Synonyms: BTZ-N3; BTZN3; BTZ N3. (S)-8-azido-2-(2-methyl-1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-6-(trifluoromethyl)-4H-benzo[e][1,3]thiazin-4-one. Grades: >98%. CAS No. 1839081-05-8. Molecular formula: C17H16F3N5O3S. Mole weight: 427.40. | |
| BTZO 1 | BTZO 1 is a macrophage migration inhibitory factor (MIF) binder (Kd = 68.6 nM). BTZO 1 activates antioxidant response element (ARE)-mediated gene expression and inhibits oxidative stress-induced cardiomyocyte apoptosis in vitro. Uses: Cardioprotective. Synonyms: BTZO1; BTZO 1; BTZO-1; 2-(2-Pyridinyl)-4H-1,3-benzothiazin-4-one. Grades: ≥99% by HPLC. CAS No. 99420-15-2. Molecular formula: C13H8N2OS. Mole weight: 240.28. | |
| BU 224 hydrochloride | BU 224 hydrochloride is a high affinity imidazoline I2 receptor ligand (Ki = 2.1 nM). It acts as an I2 antagonist that antagonizes the effects of imidazoline ligands on morphine antinociception. Synonyms: BU 224 hydrochloride; BU224 hydrochloride; BU-224 hydrochloride; 2-(4,5-Dihydroimidazol-2-yl)quinoline hydrochloride. CAS No. 205437-64-5. Molecular formula: C12H11N3.HCl. Mole weight: 233.7. | |
| BU 226 hydrochloride | BU 226 hydrochloride is a high affinity imidazoline I2 receptor ligand (Ki = 2.7 nM) with > 2000-fold selectivity for I2 imidazoline receptors over α2-adrenoceptors (Ki = 6700 nM). Synonyms: BU 226 hydrochloride; BU226 hydrochloride; BU-226 hydrochloride; 2-(4,5-Dihydroimidazol-2-yl)isoquinoline hydrochloride. CAS No. 1186195-56-1. Molecular formula: C12H11N3.HCl. Mole weight: 233.7. | |
| BU 239 hydrochloride | BU 239 hydrochloride is a high affinity imidazoline I2 receptor ligand. Synonyms: BU 239 hydrochloride; BU239 hydrochloride; BU-239 hydrochloride; SR-01000597872; J-012086; SR 01000597872; J 012086; SR01000597872; J012086; 2-(4,5-Dihydroimidazol-2-yl)quinoxaline hydrochloride. CAS No. 1217041-98-9. Molecular formula: C11H10N4.HCl. Mole weight: 234.69. | |
| Bucladesine calcium salt | Bucladesine calcium salt is a membrane permeable selective activator of PKA. It is absorbed very rapidly and almost completely when the aqueous solution is applied to the site where the skin has been excised. Besides, it is capable of significantly reducing the inflammatory oedema in the arachidonic acid induced ear oedema model in mice. Synonyms: Dibutyryl-cAMP calcium salt; DC2797 calcium salt; DC 2797 calcium salt; DC-2797 calcium salt. Grades: >98%. CAS No. 938448-87-4. Molecular formula: C18H24N5O8P·1/2Ca. Mole weight: 468.38. | |
| Bufalin | Bufalin is a major digoxin-like immunoreactive component of the Chinese medicine Chan Su and has been shown to exert a potential for anticancer activity against various human cancer cell lines in vitro. Synonyms: 22-dienolide,3,14-dihydroxy-,(3-beta,5-beta)-bufa-2; 22-dienolide,3-beta,14-dihydroxy-5-beta-bufa-2; BUFA-20,22-DIENOLIDE, 3,14-DIHYDROXY-, (3B,5B)-; BUFALIN; (3BETA,5BETA)-3,14-DIHYDROXYBUFA-20,22-DIENOLIDE; 3-BETA-14-DIHYDROXY-5-BETA-BUFA-20,22-DIENOLIDE; 3BETA,14-DIHYDROXY-5BETA,20[22]-BUFADIENOLIDE; 5BETA,20[22]-BUFADIENOLIDE-3BETA,14-DIOL. Grades: >98%. CAS No. 465-21-4. Molecular formula: C24H34O4. Mole weight: 386.52. | |
| Buflomedil Hydrochloride | Buflomedil HCl is a vasodilator used to treat claudication or the symptoms of peripheral arterial disease. Uses: Vasodilator agents. Synonyms: Buflomedil hydrochloride; Buflomedil HCl; 35543-24-9; Fonzylane; Loftyl; Buflomedil (hydrochloride); 4-(1-Pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-1-butanone hydrochloride; Buflomedil hydrochloride, European Pharmacopoeia (EP) Reference Standard; 1-BUTANONE, 4-(1-PYRROLIDINYL)-1-(2,4,6-TRIMETHOXYPHENYL)-, HYDROCHLORIDE; Buflomedil for peak identification, European Pharmacopoeia (EP) Reference Standard. Grades: >98%. CAS No. 35543-24-9. Molecular formula: C17H25NO4.HCl. Mole weight: 343.85. | |
| Buformin hydrochloride | Buformin is a potent AMPK activator and acts as an orally active biguanide antidiabetic agent. Synonyms: Imidodicarbonimidic diamide, N-butyl-, hydrochloride (1:x); Biguanide, 1-butyl-, hydrochloride; Imidodicarbonimidic diamide, N-butyl-, hydrochloride; Adebit; Butylbiguanide hydrochloride; Silubin; Silubin-retard; 1-Butylbiguanide hydrochloride (1:x); Buformine hydrochloride (1:x); Butylbiguanide hydrochloride (1:x). Grades: ≥95%. CAS No. 15537-73-2. Molecular formula: C6H15N5.xHCl. Mole weight: 157.22 (free base). | |
| Bulleyaconitine A | Bulleyaconitine A is an alkaloid found in Aconitum bulleyanum. It has analgesic and anti-inflammatory properties and has been used for the treatment of chronic pain and rheumatoid arthritis. Uses: Bulleyaconitine a, an active indegrent from aconitum bulleyanum diel, has been found to be effective in the treatment of chronic pain and rheumatoid arthritis. Synonyms: ((1-α,6-α,14-α,16-β)-8-(acetyloxy)-20-ethyl-13-hydroxy-1,6,16-trimethoxy-4-(methoxymethyl)aconitan-14-yl)(4-methoxyphenyl)-methanone; 20-ethyl-13g-hydroxy-1,6,16-trimethoxy-4-(methoxymethyl)aconitan-14-yl](4-methoxyphenyl)-methanone, [(1α, 6α, 14α, 16β) -8-(acetyloxy)-. Grades: >98%. CAS No. 107668-79-1. Molecular formula: C35H49NO9. Mole weight: 627.76. | |
| Butabindide oxalate | The oxalate salt form of Butabindide, which is a CCK-inactivating serine protease inhibitor. Synonyms: (2S)-[1-[(2S)-2-amino-1-oxobutyl]-N-butyl]-2,3-dihydro-1H-indole-2-carboxamide oxalate. Grades: ≥99% by HPLC. CAS No. 185213-03-0. Molecular formula: C17H25N3O2.C2H2O4. Mole weight: 393.44. | |
| Butamirate Impurity 1 | an impurity of Butamirate. Synonyms: Benzeneacetamide, N,?N,?α-triethyl-; Butyramide, N,N-diethyl-2-phenyl- (6CI,7CI). Grades: > 95%. CAS No. 92321-53-4. Molecular formula: C15H22O. Mole weight: 218.34. | |
| Buthionine Sulphoximine | Buthionine Sulphoximine, also known as NSC-326231, is a potent and specific inhibitor of alpha-glutamyl cysteine synthetase. Uses: Antimetabolites, antineoplastic. Synonyms: 2-amino-4-(butylsulfonimidoyl)butanoic acid; NSC-326231; NSC 326231; NSC326231; BSO; Buthionine Sulphoximine; DL-Buthionine-(S,R)-sulfoximine. CAS No. 5072-26-4. Molecular formula: C8H18N2O3S. Mole weight: 222.3. | |
| Butyl 2-fluoroprop-2-enoate | Synonyms: butyl alpha-fluoroacrylate; 2-Fluoroacrylic acid butyl ester. Grades: 95%. CAS No. 10011-39-9. Molecular formula: C7H11FO2. Mole weight: 146.16. | |
| Butyl 4-aminobenzoate | Butyl 4-aminobenzoate acts as a long-duration local anesthetic. It aids in treatment of chronic pain. It is also known to induce anti-nociception effects in subjects. It has been listed. Uses: Butyl 4-aminobenzoate acts as a long-duration local anesthetic. it aids in treatment of chronic pain. Synonyms: 4-(Butoxycarbonyl)aniline;4-Amino-benzoicacibutylester;Benzoic acid, 4-amino-, butyl ester;Benzoic acid, p-amino-, butyl ester;Butesin;Butesine;Butsein;Butyl aminobenzoate N-butyl p-aminobenzoate;Butamben. Grades: 98%. CAS No. 94-25-7. Molecular formula: C11H15NO2. Mole weight: 193.24. | |
| Butyldi-1-adamantylphosphine | Butyldi-1-adamantylphosphine (CAS# 321921-71-5 ) is a useful research chemical. Synonyms: Catacxium A; nbutyl-di(1-adamantyl)phosphine; Di(1-adamantyl)-n-butylphosphine. CAS No. 321921-71-5. Molecular formula: C24H39P. Mole weight: 358.54. | |
| Butyl oleate | Butyl Oleate is used to fabricate nanoporous anatase TiO2 mesocrystals with tunable architectures and crystal phases. Grades: 95%. CAS No. 142-77-8. Molecular formula: C22H42O2. Mole weight: 338.56800. | |
| Butylphthalide (Natural) | Cas No. 6066-49-5. | |
| Butyryl-L-carnitine chloride | (R)-Butyryl Carnitine is a potential prodrug of Carnitine, via the carnitine transporter OCTN2 and the amino acid transporter ATB0,+. It is an inhibitor of intestinal transporters, which block carnitine uptake by the carnitine transporter with IC50s of 1.5 μM and glycine transport with IC50s of 4.6 μM in in human retinal pigment epithelial (HRPE) cells. Butyryl-L-carnitine is used for treating seizure disorders. Synonyms: L-Butyrylcarnitine; C4 Carnitine. Grades: ≥95%. CAS No. 162067-50-7. Molecular formula: C11H22NO4·Cl. Mole weight: 267.8. | |
| BVT-14225 | BVT-14225 is a highly selective 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor(IC50 = 52 nM), which is 1,000 fold lower than that for 11β-HSD2. Synonyms: 2-[2-[(3-chloro-2-methylphenyl)sulfonylamino]-1,3-thiazol-4-yl]-N,N-diethylacetamide; BVT-14225; BVT 14225; BVT14225. CAS No. 376638-65-2. Molecular formula: C16H20ClN3O3S2. Mole weight: 401.93. | |
| BVT 2733 | BVT 2733 is a non-steroidal small molecule as a selective 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor (IC = 96 ± 14 nM). Synonyms: BVT-2733; BVT 2733; BVT2733; 3-chloro-2-methyl-N-(4-(2-(4-methylpiperazin-1-yl)-2-oxoethyl)thiazol-2-yl)benzenesulfonamide; Piperazine, 1-((2-(((3-chloro-2-methylphenyl)sulfonyl)amino)-4-thiazolyl)acetyl)-4-methyl-. Grades: 98%. CAS No. 376640-41-4. Molecular formula: C17H21ClN4O3S2. Mole weight: 428.95. | |
| BVT-948 | BVT 948 is a non-competitive and cell-permeable inhibitor of protein tyrosine phosphatases (PTPs) (IC50 = 0.09 - 1.7 μM). BVT 948 displays irreversible inhibition through catalysis of the hydrogen peroxide-dependent oxidation of PTP, and enhances insulin signaling in vitro and insulin tolerance in ob/ob mice in vivo. Some cytochrome P450 isoforms are also suppressed by BVT 948 (IC50 <10 μM). Synonyms: BVT948; BVT-948; BVT 948; SPS8I3; SPS-8I3; SPS 8I3; 4-Hydroxy-3,3-dimethyl-2H-benz[g]indole-2,5(3H)-dione. Grades: ≥98% by HPLC. CAS No. 39674-97-0. Molecular formula: C14H11NO3. Mole weight: 241.24. | |
| BW-A78U | BW-A 78U is a PDE4 inhibitor with an IC50 of 3 μM. BW-A 78U fails to significantly inhibit arachidonate release. It is ineffective to inhibit the lipopolysaccharide (LPS)-induced TNF-α release. Synonyms: BW A78U. Grades: ≥98%. CAS No. 101155-02-6. Molecular formula: C13H12FN5. Mole weight: 257.27. | |
| BX 430 | BX 430 is a selective P2X4 allosteric antagonist (IC50 = 0.54 μM) binding noncompetitively to extracellular allosteric site. It exhibits >10-fold selectivity for human P2X4 receptors over P2X1, P2X2, P2X3, P2X5 and P2X7 receptors. BX 430 is inactive at mouse and rat P2X4 receptors. Synonyms: BX430; BX-430; BX 430; N-[2,6-Dibromo-4-(1-methylethyl)phenyl]-N'-(3-pyridinyl)urea. Grades: ≥99% by HPLC. CAS No. 688309-70-8. Molecular formula: C15H15Br2N3O. Mole weight: 413.11. | |
| BX-517 | BX-517, also known as PDK1 inhibitor2, is a cell-permeable indolinone compound that acts as a potent, ATP site-targeting PDK1 inhibitor (IC50 = 6 nM). BX-517 also blocks activation of Akt in tumor cells with 10-fold more potent (IC50 = 0.1-1.0 μM) than its analogs tested at the highest dose tested (10 μM). Synonyms: (Z)-N-(3-(1-(1H-pyrrol-2-yl)ethylidene)-2-hydroxy-3H-indol-5-yl)carbamimidic acid; BX-517; BX 517; BX517; PDK1 inhibitor2. CAS No. 850717-64-5. Molecular formula: C15H14N4O2. Mole weight: 282.3. | |
| BX912 | BX-912 is a selective inhibitor of 3-Phosphoinositide-dependent Kinase-1 (PDK1) with IC50 of 12 nM; >10 fold selectivity over PKA, PKC, C-Kit, EGFR etc. Synonyms: BX912; BX 912; BX-912. Grades: 0.98. CAS No. 702674-56-4. Molecular formula: C20H23BrN8O. Mole weight: 471.363. | |
| Byakangelicol | Byakangelicol is a furanocoumarin derivative which shows inhibitory effects against P-glycoprotein at the blood-brain barrier. It acts as an anti-proliferative agent causing G2/M arrest in melanoma cells. Synonyms: (R)-(+)-9-(2,3-Epoxy-3-methylbutoxy)-4-methoxy-7H-furo[3,2-g][1]benzopyran-7-one. Grades: >98%. CAS No. 26091-79-2. Molecular formula: C17H16O6. Mole weight: 316.3. | |
| Bz 423 | Bz 423 has been found to be an ATP synthase inhibitor and could suppress disease in lupus-prone mice at some extent. Uses: Immunologic factors. Synonyms: Bz-423; Bz 423; Bz423; 7-Chloro-1,3-dihydro-5-(4-hydroxyphenyl)-1-methyl-3-(2-naphthalenylmethyl)-2H-1,4-benzodiazepin-2-one. Grades: ≥98% by HPLC. CAS No. 216691-95-1. Molecular formula: C27H21ClN2O2. Mole weight: 440.92. | |
| C14TKL-1 | C14TKL-1 is an endogenous human tachykinin-like peptide and a potent NK1 receptor agonist (EC50 = 1 nM). Synonyms: H-Arg-His-Arg-Thr-Pro-Met-Phe-Tyr-Gly-Leu-Met-NH2; L-arginyl-L-histidyl-L-arginyl-L-threonyl-L-prolyl-L-methionyl-L-phenylalanyl-L-tyrosyl-glycyl-L-leucyl-L-methioninamide; Chromosome 14 tachykinin-like peptide 1; C14TKL1; C14TKL 1. Grades: ≥95%. CAS No. 1423381-12-7. Molecular formula: C63H98N20O13S2. Mole weight: 1407.71. | |
| C16 | C16 is an inhibitor of RNA-activated protein kinase (PKR) (IC50 = 210 nM). It is an imidazolo-oxindole derivative that binds to ATP-binding site of PKR and rescues PKR-dependent translation block in vitro. C16 has neuroprotective activity against cell damage in human neuroblastoma cells and neuroinflammation in acute excitotoxic rat model. Synonyms: GW-506033X; GW 506033X; GW506033X; C16, PKR Inhibitor; 6,8-Dihydro-8-(1H-imidazol-5-ylmethylene)-7H-pyrrolo[2,3-g]benzothiazol-7-one. Grades: ≥98% by HPLC. CAS No. 608512-97-6. Molecular formula: C13H8N4OS. Mole weight: 268.29. | |
| C18 L-erythro Ceramide (d18:1/18:0) | C18 L-erythro Ceramide is a naturally occurring ceramide and stereoisomer of C18 ceramide. It can inhibit rat brain mitochondrial ceramidase (mt-CDase) with an IC50 value of 8.8 μM. Synonyms: L-erythro Cer(d18:1/18:0); L-erythro Ceramide (d18:1/18:0); N-octadecanoyl-L-erythro-sphingosine. Grades: ≥98%. CAS No. 252039-52-4. Molecular formula: C36H71NO3. Mole weight: 565.95. | |
| C18 L-threo Ceramide (d18:1/18:0) | C18 L-threo Ceramide is a synthetic ceramide and stereoisomer of C18 ceramide that has been used for structural characterization of natural sphingolipids. It inhibits rat brain mitochondrial ceramidase (mt-CDase) with an IC50 value of 16.8 μM. Synonyms: N-octadecanoyl-L-threo-sphingosine; L-threo Cer(d18:1/18:0); L-threo Ceramide (d18:1/18:0). Grades: ≥98%. CAS No. 95037-06-2. Molecular formula: C36H71NO3. Mole weight: 565.95. | |
| C29 | C29 is a potential TLR2 inhibitor. C29 inhibited TLR2/1 and TLR2/6 signaling induced by synthetic and bacterial TLR2 agonists in human HEK-TLR2 and THP-1 cells, but only TLR2/1 signaling in murine macrophages. Synonyms: TLR2-IN-C29; TLR2 IN C29; TLR2INC29; TLR2-inhibitor-C29; TLR2 inhibitor-C29; TLR2 inhibitor C29. CAS No. 363600-92-4. Molecular formula: C16H15NO4. Mole weight: 285.30. | |
| C2 Adamantanyl Galactosylceramide (d18:1/2:0) | C2 Adamantanyl Galactosylceramide (d18:1/2:0) is a bioactive sphingolipid. It reduces globotriaosylceramide 3 synthesis from exogenous lactosylceramide in microsomes. AdaGalCer stimulates recombinant glucocerebrosidase activity in a pH-dependent manner. It activates glucocerebrosidase to decrease glucosylceramide accumulation in fibroblasts and lymphoblasts isolated from patients with Gaucher and Fabry disease, respectively. Synonyms: [(2S,3R,4E)-2-[(1-Adamantyl)acetylamino]-3-hydroxy-4-octadecenyl]beta-D-galactopyranoside; N-(1-Adamantaneacetyl)-galactosylceramide; Adamantanyl Galactosyl(β) Ceramide; AdaGalCer(d18:1/2:0). Grades: ≥98%. CAS No. 574738-16-2. Molecular formula: C36H63NO8. Mole weight: 637.89. | |
| C2 Adamantanyl Glucosylceramide (d18:1/2:0) | C2 Adamantanyl glucosylceramide (AdaGluCer) is a bioactive sphingolipid. It increases levels of glycosphingolipids in Vero cells at low concentrations (≤20 μM) but decreases them at high concentrations (≥40 μM). Pretreatment of microsomes with AdaGluCer increases production of adamantanyl lactosylceramide (AdaLacCer) and reduces synthesis of LacCer from exogenous GlcCer. AdaGluCer inhibits glucocerebrosidase activity in vitro in a pH-dependent manner. Synonyms: N-(1-Adamantaneacetyl) Glucosylceramide; Adamantanyl GluCer(d18:1/2:0); Adamantanyl Glucosylceramide (d18:1/2:0); AdaGluCer(d18:1/2:0). Grades: ≥98%. Molecular formula: C36H61NO8. Mole weight: 635.87. | |
| C3a Receptor Agonist | Complement 3a (C3a) Receptor Agonist is a G protein-coupled receptor protein involved in the complement system complement pathway. C3aRs are expressed on neural progenitor cells and immature neurons in adult mice. It stimulates differentiation of neural progenitor cells in vitro. Synonyms: C3A Receptor Agonist; 944997-60-8; C3a receptor agonist 1; 2-cyclohexyl-2-phenyl-N-[1-(3-pyridin-3-ylpropanoyl)piperidin-4-yl]acetamide; CHEMBL390036; CHEMBL535625; 2-cyclohexyl-2-phenyl-N-(1-(3-(pyridin-3-yl)propanoyl)piperidin-4-yl)acetamide; 2-Cyclohexyl-2-phenyl-N-{1-[3-(pyridin-3-yl)propanoyl]piperidin-4-yl}acetamide; Complement 3a Receptor Agonist; SCHEMBL14335900; GTPL11252; DTXSID90659061; BDBM50423085; AKOS028114559; compound 7 [PMID: 17459702]; MS-27755; HY-128132; CS-0095343; C3A Receptor Agonist, >=98% (HPLC), solid; F87576. Grades: ≥98%. CAS No. 944997-60-8. Molecular formula: C27H35N3O2. Mole weight: 433.6. | |
| C3-Spacer-CEP | C3-Spacer-CEP is used to insert a spacer arm in an oligonucleotide and may be added in multiple additions when a longer spacer is required. Synonyms: 3-(4,4'-Dimethoxytrityloxy)propyl-1-[(2-cyanoethyl)-(N,N-diisopropyl)] phosphoramidite; Spacer Phosphoramidite C3. Grades: ≥98.0%. CAS No. 110894-23-0. Molecular formula: C33H43N2O5P. Mole weight: 578.68. | |
| C527 | C527 is an inhibitor of USP1/UAF complex deubiquitinase activity. It is a high potency for the USP1/UAF1 complex with IC50 of 0.88 μM. C527 increases ubiquinated Fanconi anemia complementation group D2 (FANCD2-Ub) and FANCI-Ub levels in a concentration-dependent manner. It also inhibits homologous recombination repair, cell proliferation, and sensitizes HeLa cells to the DNA crosslinker mitomycin C. Synonyms: C-527; C 527. Grades: ≥98%. CAS No. 192718-06-2. Molecular formula: C17H8FNO3. Mole weight: 293.3. | |
| C646 | C646 is an inhibitor for histone acetyltransferase, and inhibits p300 with a Ki of 400 nM. Preferentially selective for p300 versus other acetyltransferases. Synonyms: C646; C-646; C 646. Grades: >98%. CAS No. 328968-36-1. Molecular formula: C24H19N3O6. Mole weight: 445.42. | |
| C75 | C75 is a novel, potent synthetic inhibitor of fatty acid synthase (FAS), which is used as a tool for studying fatty acid synthesis in metabolic disorders and cancer. Synonyms: C 75 trC-75 trans-racemic; trans-C75; C 75; C75; C-75. Grades: >98%. CAS No. 218137-86-1. Molecular formula: C14H22O4. Mole weight: 254.32. | |
| C75 trans | trans-Tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylic Acid is a well-known fatty acid synthase (FAS) inhibitor. Studies show that trans-Tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylic Acid is a cell cycle arrest inducer in hepatocellular carcinoma (HCC) cell lines. It has also been shown to blocks resistin-induced increases in lipid accumulation by human macrophages. Synonyms: C 75 trC-75 trans-racemic; trans-C75. Grades: >98%. CAS No. 191282-48-1. Molecular formula: C14H22O4. Mole weight: 254.32. | |
| C 87 | C 87 is a TNF-α inhibitor (Kd = 110 nM for hTNF-α). It was shown to inhibit TNF-α-induced cytotoxicity in L929 fibroblast cells, attenuate inflammation and increase survival in a mouse hepatitis model. Synonyms: TNFalpha-IN-C87; 3-Phenyl-1-(4-phenyl-2-thiazolyl)-1H-pyrazole-4,5-dione 4-[2-(4-chloro-3-nitrophenyl)hydrazone]. Grades: ≥98% by HPLC. CAS No. 332420-90-3. Molecular formula: C24H15ClN6O3S. Mole weight: 502.93. | |
| CA-170 | A first-in-class oral, small molecule antagonist of PD-L1, PD-L2 and V-region immunoglobulin-containing suppressor of T cell activation (VISTA). Synonyms: CA-170; CA 170; CA170. Molecular formula: C12H20N6O7. Mole weight: 360.32. | |
| CA-5f | CA-5f is a potent late-stage macroautophagy/autophagy inhibitor via inhibiting autophagosome-lysosome fusion. It exhibited strong cytotoxicity against A549 non-small cell lung cancer (NSCLC) cells. CA-5f effectively suppressed the growth of A549 lung cancer xenograft as a single agent with an excellent tolerance in vivo. Synonyms: CA5f. Grades: ≥98%. CAS No. 1370032-19-1. Molecular formula: C24H24N2O3. Mole weight: 388.46. | |
| Cabazitaxel | Cabazitaxel increases CYP3A enzyme activities in rat hepatocytes. The mean ex-vivo human plasma protein binding of Cabazitaxel is 91.6%. Synonyms: XRP6258; XRP-6258; XRP 6258; TXD 258; TXD-258; TXD258; RPR116258A; axoid XRP6258; dimethoxydocetaxel US brand name: Jevtana. Grades: >98%. CAS No. 183133-96-2. Molecular formula: C45H57NO14. Mole weight: 835.93. | |
| Cabergoline Impurity A | 6-Allyl-8β-carboxyergoline is a metabolite of cabergoline which is a dopamine D2-receptor agonist. Synonyms: (8β)-6-(2-Propen-1-yl)-ergoline-8-carboxylic Acid; 6-(2-Propenyl)dihydrolysergic Acid; FCE 21589. Grades: > 95%. CAS No. 81409-74-7. Molecular formula: C18H20N2O2. Mole weight: 296.37. | |
| Cabergoline Impurity B | European Pharmacopoeia (EP) Impurity B of Cabergoline. Synonyms: (8β)-N8-[3-(Dimethylamino)propyl]-N1-ethyl-6-(2-propen-1-yl)-ergoline-1,8-dicarboxamide; (8β)-N8-[3-(Dimethylamino)propyl]-N1-ethyl-6-(2-propenyl)-ergoline-1,8-dicarboxamide; Cabergoline EP Impurity B. Grades: > 95%. CAS No. 166533-36-4. Molecular formula: C26H37N5O2. Mole weight: 451.62. | |
| Cabergoline Impurity C | European Pharmacopoeia (EP) Impurity C of Cabergoline. Synonyms: (8β)-N8-[3-(Dimethylamino)propyl]-N1-ethyl-N8-[(ethylamino)carbonyl]-6-(2-propen-1-yl)-ergoline-1,8-dicarboxamide; (8β)-N8-[3-(dimethylamino)propyl]-N1-ethyl-N8-[(ethylamino)carbonyl]-6-(2-propenyl)--ergoline-1,8-dicarboxamide. Grades: > 95%. CAS No. 126554-50-5. Molecular formula: C29H42N6O3. Mole weight: 522.7. | |
| Cabergoline Impurity D | A metabolite of Cabergoline, having affinity for D1 and D2 dopamine receptors in rat striatum. Synonyms: N-[3-(Dimethylamino)propyl]-6-(2-propen-1-yl)-(8β)-ergoline-8-carboxamide; (5R,8R,10R)-6-Allyl-N-[3-(dimethylamino)propyl]ergoline-8-carboxamide; FCE 21590. Grades: > 95%. CAS No. 85329-86-8. Molecular formula: C23H32N4O. Mole weight: 380.54. | |
| Cafestol | Cafestol is a natural bioactive substance isolated from the unsaponifiable fraction of petroleum ether extract of coffee beans, it acts as a GST (glutathione S-transferase) inducer and exhibits chemoprotective activity. Dietary cafestol does increase total cholesterol and triglycerides in ApoE3Leiden mice, an effect which is associated with selective activation of farnesoid X receptors and pregnane X receptors. Synonyms: cafestol; 469-83-0; cafesterol; CCRIS 1518; AC465T6Q6W; CHEBI:3291; (3bS,5aS,7R,8R,10aR,10bS)-7-(hydroxymethyl)-10b-methyl-3b,4,5,6,7,8,9,10,10a,10b,11,12-dodecahydro-5a,8-methanocyclohepta[5,6]naphtho[2,1-b]furan-7-ol. Grades: ≥98%. CAS No. 469-83-0. Molecular formula: C20H28O3. Mole weight: 316.4. | |
| Caffeic acid-pYEEIE | Caffeic acid-pYEEIE has been found to be a phosphopeptide ligand. Synonyms: N-[3-(3,4-Dihydroxyphenyl)-1-oxo-2-propenyl]-O-phosphono-L-tyrosyl-L-α-glutamyl-L-α-glutamyl-L-isoleucyl-L-glutamic acid. Grades: ≥95% by HPLC. CAS No. 507471-72-9. Molecular formula: C39H50N5O19P. Mole weight: 923.82. | |
| Caftaric acid | Caftaric acid is a natural compound found in the juice of grapes. It is an inhibitor of the protein-protein interactions mediated by the Src-family kinases. Uses: Used in cancer therapy as an anticancer drug. Synonyms: 2-Caffeoyl-L-tartaric acid; (2R,3R)-2-{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}-3-hydroxybutanedioic acid. Grades: >98%. CAS No. 67879-58-7. Molecular formula: C13H12O9. Mole weight: 312.23. | |
| Calcineurin substrate | Calcineurin substrate is a peptide from the regulatory RII subunit of cAMP-dependent protein kinase. Synonyms: H-Asp-Leu-Asp-Val-Pro-Ile-Pro-Gly-Arg-Phe-Asp-Arg-Arg-Val-Ser-Val-Ala-Ala-Glu-OH; L-alpha-aspartyl-L-leucyl-L-alpha-aspartyl-L-valyl-L-prolyl-L-isoleucyl-L-prolyl-glycyl-L-arginyl-L-phenylalanyl-L-alpha-aspartyl-L-arginyl-L-arginyl-L-valyl-L-seryl-L-valyl-L-alanyl-L-alanyl-L-glutamic acid. Grades: 98%. CAS No. 113873-67-9. Molecular formula: C92H150N28O29. Mole weight: 2112.35. | |
| Calcipotriol (Calcipotriene) | Cas No. 112965-21-6. | |
| Calcipotriol Impurity 1 | (5E,24R)-Calcipotriene is an analog of (5E)-Calcipotriene ; the trans-isomeric impurity of Calcipotriene and a vitamin D3 analogue with antitumor effects. Synonyms: (1α,3β,5E,7E,22E,24R)-24-Cyclopropyl-9,10-secochola-5,7,10(19),22-tetraene-1,3,24-triol; (1R,3S,E)-5-((E)-2-((1R,3aS,7aR)-1-((2R,5R,E)-5-Cyclopropyl-5-hydroxypent-3-en-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-4-methylenecyclohexane-1,3-. Grades: > 95%. CAS No. 112849-47-5. Molecular formula: C27H40O3. Mole weight: 412.62. | |
| Calcipotriol Impurity A | Cas No. 126860-83-1. | |
| Calcipotriol Impurity C | Cas No. 113082-99-8. | |
| Calcipotriol Impurity D | Cas No. 112827-99-3. | |
| Calcipotriol Impurity F | Cas No. 112875-61-3. | |
| Calcipotriol Impurity G | |
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