BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| CAY10621 | Sphingosine kinase (SphK) is a conserved lipid kinase that catalyzes formation sphingosine-1-phosphate (S1P) from the precursor sphingolipid sphingosine. The two known kinases, sphingosine kinase 1 (SphK1) and sphingosine kinase 2 (SphK2), have different developmental and tissue expression patterns, suggesting that they have distinct physiological functions. CAY10621 is an inhibitor of SPHK1 with IC50 of 3.3 μM. It is selective for SphK1 over Sph2 at 10 μM and PKC at concentrations less than 100 μM. CAY10621 inhibits SphK1 activity by 70% in U937 cells at 5 μM. Synonyms: SKI 5C; SPHK1 Inhibitor 5C; CAY 10621; CAY-10621. Grades: ≥98%. CAS No. 120005-55-2. Molecular formula: C26H45NO4. Mole weight: 435.6. |  |
| CAY10640 | Soluble epoxide hydrolase (sEH) is a bifunctional enzyme that in humans is encoded by the EPHX2 gene. sEH is a member of the epoxide hydrolase family. CAY10640 is a 1-aryl-3-(1-acylpiperidin-4-yl)urea analog that inhibits recombinant human and mouse sEH with IC50 values both equal to 0.4 nM. Synonyms: sEHi; Soluble Epoxide Hydrolase Inhibitor; CAY 10640; CAY-10640. Grades: ≥98%. CAS No. 1208549-68-1. Molecular formula: C17H20F3N3O3. Mole weight: 371.4. | |
| CAY10677 | Isoprenylcysteine Carboxyl Methyltransferase (ICMT) is a protein coding gene. Diseases associated with ICMT include Hallermann-Streiff syndrome and Legionnaire disease. CAY10677 is an analog of the ICMT inhibitor cysmethynil that was developed for improved solubility and cell permeability. It inhibits ICMT with an IC50 value of 0.86 μM and demonstrates nearly 10-fold more potent antiproliferative activity than cysmethynil on human breast cancer MDA-MB-231 cells and human prostate cancer PC3 cells. Synonyms: Icmt Inhibitor 15; CAY 10677; CAY-10677. Grades: ≥98%. CAS No. 1443253-20-0. Molecular formula: C25H37N5. Mole weight: 407.6. | |
| CAY10680 | The monoamine oxidases A and B are the products of two abutting X-linked genes, and play an important role in the metabolism of biogenic amines in the central nervous system. Inhibition of MAO-B is considered as a strategy to treat Parkinson's disease. CAY10680 is a benzothiazinone compound that selectively inhibits MAO-B with IC50 = 34.9 nM in human. The blockade of adenosine A2A receptors has emerged as a potential treatment for Parkinson's disease. CAY10680 has been shown to abolish cAMP accumulation in CHO cells transfected with adenosine A2A receptors. It can selectively inhibits with Ki of 39.5 nM in human. Synonyms: CAY 10680; CAY-10680. Grades: ≥98%. CAS No. 1439488-21-7. Molecular formula: C18H16N2O2S. Mole weight: 324.4. | |
| CAY10683 | Santacruzamate A (CAY10683) is a potent and selective HDAC inhibitor with IC50 of 119 pM for HDAC2, >3600-fold selectivity over other HDACs. Uses: Histone deacetylase inhibitors. Synonyms: CAY10683; CAY-10683; CAY 10683; Santacruzamate A. Grades: >98%. CAS No. 1477949-42-0. Molecular formula: C15H22N2O3. Mole weight: 278.35. | |
| CAY10717 | CAY10717 is a multi-targeted kinase inhibitor that exhibits greater than 40% inhibition of 34 of 104 kinases in an enzymatic assay at 100 nM. CAY10717 is highly cytotoxic against a cancer cell panel that includes chemotherapy-sensitive and -resistant cell lines (EC50s = 0.4-158 nM). It also inhibits the growth of human umbilical vein endothelial cells (HUVECs) with EC50 of 34 nM. Synonyms: CAY 10717; CAY-10717. Grades: ≥95%. CAS No. 1240322-54-6. Molecular formula: C29H25F3N6O3. Mole weight: 562.5. | |
| CAY10719 | ABCG2 is a constitutively expressed ATP-binding cassette (ABC) transporter that protects many tissues against xenobiotic molecules. CAY10719 is a selective inhibitor of the breast cancer resistance protein ABCG2 with IC50 of 0.23 μM. It has been shown to reverse the ABCG2-mediated resistance toward SN 38 and inhibit ATPase activity. Synonyms: CAY 10719; CAY-10719. Grades: ≥98%. CAS No. 1942919-63-2. Molecular formula: C25H20Cl2N2O2. Mole weight: 451.3. | |
| CAY10734 | Sphingosine-1-phosphate receptor (S1P) modulators are a class of drugs used as immunomodulators, most notably in cases of multiple sclerosis. CAY10734 is an agonist of sphingosine-1-phosphate receptor 1 (S1P1) with IC50=0.6 nM). It selectively binds S1P1 over S1P2, S1P3, and S1P4 receptors (IC50s = >10,000, 12,000, and 70 nM, respectively) but does also bind S1P5 receptors (IC50 = 1 nM) in radioligand binding assays. Synonyms: CAY 10734; CAY-10734. Grades: ≥98%. CAS No. 635701-59-6. Molecular formula: C23H25N3O3. Mole weight: 391.5. | |
| CAY10739 | Sphingosine-1-phosphate receptor (S1P) modulators are a class of drugs used as immunomodulators, most notably in cases of multiple sclerosis. CAY10739 is a soft-drug agonist of the sphingosine-1-phosphate receptor 1 (S1P1) with IC50=25.12 nM in a β-arrestin recruitment assay, which was designed to prevent systemic effects following topical application. It is selective for S1P1 over S1P2, S1P3, and S1P4 (IC50s = 1,000, >10,000, >10,000 nM, respectively). Synonyms: CAY 10739; CAY-10739. Grades: ≥98%. Molecular formula: C23H24N2O3S. Mole weight: 408.51. | |
| CB 1837 | CB 1837 was the parent member of a series of nitrophenyl aziridines evaluated for antitumour activity by Khan and Ross. Synonyms: 1-(2,4-dinitrophenyl)aziridine; CB 1837; CB1837; CB-1837; AI3-51871; NSC 3375. Grades: 95%. CAS No. 27141-65-7. Molecular formula: C8H7N3O4. Mole weight: 209.159. | |
| CB-25 | Δ9-Tetrahydrocannabinol (THC) is the primary psychoactive constituent of cannabis and an active cannabinoid pharmacotherapy component. Anandamide (AEA), also known as N-arachidonoylethanolamine, is an endogenous lipid with cannabinergic activity. CB-25 is a stable analog of Δ9-tetrahydrocannabinol (THC) and anandamide (AEA). It exhibits high affinity for the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors with Ki values of 5.2 and 13 nM, respectively. Synonyms: CB25; CB 25. Grades: ≥98%. CAS No. 869376-63-6. Molecular formula: C25H41NO3. Mole weight: 403.6. | |
| CB30900 | CB30900 has been found to be a thymidylate synthase inhibitor that could have some extent of activity in models with low or defective folylpolyglutamate synthetase. Synonyms: CB 30900; CB30900; CB-30900; N-(N-(4-(N-((3,4-Dihydro-2,7-dimethyl-4-oxo-6-quinazolinyl)methyl)-N-prop-2-ynylamino)-2-fluorobenzoyl)-L-gamma-glutamyl)-D-glutamic acid. Grades: 98%. CAS No. 145788-82-5. Molecular formula: C31H32FN5O9. Mole weight: 637.61. | |
| CB 3703 | CB 3703 is an inhibitor of hydrofolate reductase. Uses: An inhibitor of hydrofolate reductase. Synonyms: CB 3703; CB3703; CB-3703; NSC 289522. N-(p-(((2,4-Diamino-5-methyl-6-quinazolinyl)methyl)amino)benzoyl)-L-glutamic acid;L-Glutamic acid, N-(4-(((2,4-diamino-5-methyl-6-quinazolinyl)methyl)amino)benzoyl)-. Grades: ≥95%. CAS No. 32093-09-7. Molecular formula: C22H24N6O5. Mole weight: 452.18. | |
| CB 3731 | CB 3731 can be used in fluorine-19 nuclear magnetic resonance studies of binary and ternary complexes of thymidylate synthase. Synonyms: CB 3731; CB-3731; CB3731. N-(4-((N-(2-Amino-4-hydroxy-6-quinazolinyl)methyl)-N-(fluoroethyl)amino)benzoyl)glutamic acid. Grades: 98%. CAS No. 80015-07-2. Molecular formula: C23H24FN5O6. Mole weight: 458.47. | |
| CB-3988 | CB 3988 is a bio-active chemical compound. Synonyms: CB 3988; CB-3988; CB3988. (2S)-2-[2-Trifluoromethyl-4-[N-[(3,4-dihydro-2-methyl-4-oxoquinazolin)-6-ylmethyl]-N-(2-propynyl)amino]benzoylamino]glutaric acid;N-[2-Trifluoromethyl-4-[2-propynyl[(3,4-dihydro-4-oxo-2-methylquinazolin)-6-ylmethyl]amino]benzoyl]-L-glutamic acid; (2S) -2-[[4-[ (2-methyl-4-oxo-1H-quinazolin-6-yl) methyl-prop-2-ynylamino]-2- (trifluoromethyl) benzoyl]amino]pentanedioic acid. Grades: >98%. CAS No. 112888-26-3. Molecular formula: C26H23F3N4O6. Mole weight: 544.48. | |
| CB5083 | CB-5083 is a novel first in class, potent orally bio-available p97 inhibitor that disrupts cellular protein homeostasis and demonstrates anti-tumor activity in solid and hematological models. CB-5083 causes rapid and sustained accumulation of poly-ubiquitin in tumor xenografts after a single administration. CB-5083 showed activity to inhibit tumor growth in multiple rodent models of human cancer. Furthermore, CB-5083 appears to exhibit greater potency over current proteasome inhibitors that further validate targeting p97 and protein homeostasis in the treatment of cancer. Synonyms: CB5083; CB-5083; CB 5083. Grades: >98%. CAS No. 1542705-92-9. Molecular formula: C24H23N5O2. Mole weight: 413.4. | |
| CB-52 | Δ9-Tetrahydrocannabinol (THC) is the primary psychoactive constituent of cannabis and an active cannabinoid pharmacotherapy component. Anandamide (AEA), also known as N-arachidonoylethanolamine, is an endogenous lipid with cannabinergic activity. CB-52 is a stable analog of Δ9-tetrahydrocannabinol (THC) and anandamide (AEA). It exhibits high affinity for the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors with Ki values of 210 and 30 nM, respectively. Synonyms: CB52;CB 52. Grades: ≥98%. CAS No. 869376-90-9. Molecular formula: C26H43NO3. Mole weight: 417.6. | |
| CB7646 | CB7646 is a stable analogue of trimelamol (TM). It is used as an anti-tumour agent. Uses: Cb7646 is used as an anti-tumour agent. Synonyms: CB-7646; CB 7646; CB7646; UNII-LYO93N5MEB. Methanol, ((6-(methylamino)-1,3,5-triazine-2,4-diyl)bis(methylimino))bis-;[[4-[Hydroxymethyl(methyl)amino]-6-(methylamino)-1,3,5-triazin-2-yl]-methylamino]methanol. Grades: >98 %. CAS No. 104880-54-8. Molecular formula: C8H16N6O2. Mole weight: 228.25. | |
| CB 966 | CB 966 is a novel analogues of 1,25-dihydroxyvitamin D3 and it was found to significantly delay the rejection of allogeneic skin grafts in CBA (H-2k) recipient mice. Synonyms: CB 966; CB966; CB-966. (1R-(1alpha(R*), 3abeta, 4E(1R*, 3S*, 5Z), 7aalpha))-5-((1-(6-ethyl-6-hydroxy-1-methyloctyl)octahydro-7a-methyl-4H-inden-4-ylidene)ethylidene)-4-methylene-1, 3-Cyclohexanediol. Grades: 98%. CAS No. 128312-71-0. Molecular formula: C30H50O3. Mole weight: 458.72. | |
| CBFβ Inhibitor | Core binding factors (CBFs) are heterodimeric transcription factors containing a DNA-binding CBFα component (a RUNX protein) and an enhancer of binding, CBF&beta. CBFβ Inhibitor cellular studies indicate a good correlation between the inhibitor's antiproliferative activity and the Runx1 expression level in the target cells. Synonyms: Core Binding Factor-β Inhibitor; 2-Thiazolamine, 5-ethyl-4-(4-methoxyphenyl)-; 5-Ethyl-4-(4-methoxyphenyl)-2-thiazolamine; Sc 221405; 5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine. Grades: ≥98%. CAS No. 493028-20-9. Molecular formula: C12H14N2OS. Mole weight: 234.32. | |
| CBR 5884 | CBR 5884 is a 3-Phosphoglycerate dehydrogenase (PHGDH) inhibitor (IC50 = 33 μM), does not affect other NAD+-dependent dehydrogenases. Uses: 3-phosphoglycerate dehydrogenase (phgdh) inhibitor. Synonyms: CBR-5884; CBR 5884; CBR5884. Ethyl 5-[(2-furanylcarbonyl)amino]-3-methyl-4-thiocyanato-2-thiophenecarboxylate. Grades: ≥98%. CAS No. 681159-27-3. Molecular formula: C14H12N2O4S2. Mole weight: 336.39. | |
| CC-12074 | A Metabolite of Pomalidomide. Uses: Pomalidomide metabolite. Synonyms: CC-12074; CC12074; CC 12074; Pomalidomide metabolite M19; UNII-A480CC1Z8I; SCHEMBL3742152.4-amino-2-(5-hydroxy-2,6-dioxopiperidin-3-yl)isoindole-1,3-dione. Grades: ≥98%. CAS No. 460741-57-5. Molecular formula: C13H11N3O5. Mole weight: 289.24. | |
| CC-17369 | CC-17369, a hydroxyisoindole derivative, is a metabolites of pomalidomide and has potential activity in anticancer study like multiple myeloma. Synonyms: CC-17369; CC 17369; CC17369; Pomalidomide metabolite M16; M16(CC-17369); SCHEMBL15439588; 4-amino-2-(2,6-dioxopiperidin-3-yl)-7-hydroxyisoindole-1,3-dione. Grades: 98%. CAS No. 1547162-46-8. Molecular formula: C13H11N3O5. Mole weight: 289.25. | |
| CC-3052 | CC-3052, a thalidomide analogue, reduces persistent activation of the TNF-α system in HIV without markedly impairing neutrophil viability. Synonyms: CC-3052; CC 3052; CC3052; methyl (2R)-2-(3,4-dimethoxyphenyl)-3-(3-oxo-1H-isoindol-2-yl)propanoate. Grades: >98%. CAS No. 216884-02-5. Molecular formula: C20H21NO5. Mole weight: 355.38. | |
| CC-671 | CC-671 is a novel dual TTK Protein Kinase/CDC2-Like Kinase (CLK2) inhibitor with IC50s of 5 and 3 nM, which is used for the treatment of triple negative breast cancer initiated from a phenotypic screen. It is selective for Mps1/TTK and Clk2 over a panel of 255 kinases at 3 μM, but does inhibit DYRK3, DYRK1A, PHKG, DYRK1B, and Clk1 (IC50s = 99, 104, 136, 157, and 300 nM, respectively). Synonyms: CC671; CC 671. Grades: ≥95%. CAS No. 1618658-88-0. Molecular formula: C28H28N6O4. Mole weight: 512.6. | |
| CCF-642 | CCF-642 is a protein disulfide isomerase (PDI) inhibitor that exhibits 100-fold higher potency than PACMA 31 (by di-E-GSSG assay) via an alternative mode of action. CCF642 displayed potent efficacy in an aggressive syngeneic mouse model of multiple myeloma and prolonged the lifespan of C57BL/KaLwRij mice engrafted with 5TGM1-luc myeloma, an effect comparable to the first-line multiple myeloma therapeutic bortezomib. Synonyms: 3-(4-Methoxyphenyl)-5-[(5-nitro-2-thienyl)methylene]-2-thioxo-4-thiazolidinone; CCF-642; CCF 642; CCF642. CAS No. 346640-08-2. Molecular formula: C15H10N2O4S3. Mole weight: 378.44. | |
| CCG-100602 | CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells with an IC50 value of 9.8 μM. CCG-100602 specifically blocks the nuclear localization of MRTF-A, thereby inhibiting the fibrogenic transcription factor SRF. Synonyms: CCG-100602; 1207113-88-9; 1-[3,5-bis(trifluoromethyl)benzoyl]-N-(4-chlorophenyl)piperidine-3-carboxamide; CHEMBL603141; compound 4g [PMID: 19963382]; 1-(3,5-bis(trifluoromethyl)benzoyl)-N-(4-chlorophenyl)piperidine-3-carboxamide; CCG100602; CCG 100602; GTPL6764; SCHEMBL1534209; BDBM50436237; AKOS040744973; MS-28902; HY-120855; CS-0079376; Q27075763; [3,5-bis(trifluoromethyl)benzoyl]-N-(4-chlorophenyl)piperidine-3-carboxamide; 1-[3,5-bis (trifluoromethyl)benzoyl]-N-(4-chlorophenyl)-3-piperidinecarboxamide. Grades: 98%. CAS No. 1207113-88-9. Molecular formula: C21H17ClF6N2O2. Mole weight: 478.8. | |
| CCG 203971 | CCG 203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50 = 6.4 μM). CCG 203971 inhibits fibrosis by targeting the MRTF/SRF gene transcription pathway, and inhibits proliferation of SSc-derived dermal fibroblasts. It also suppresses PC-3 cell migration in scratch wound assays (IC50 = 4.2 μM). Synonyms: CCG-203971; CCG 203971; CCG203971. N-(4-Chlorophenyl)-1-[3-(2-furanyl)benzoyl]-3-piperidinecarboxamide. Grades: ≥98% by HPLC. CAS No. 1443437-74-8. Molecular formula: C23H21ClN2O3. Mole weight: 408.88. | |
| CCG 2046 | CCG 2046 is an inhibitor of regulator of G-protein signaling 4 (RGS4). It reduces the RGS4-Gαo protein-protein interaction signal. Synonyms: CCG 2046; CCG2046; CCG-2046; 3-Methyl-3-propyl-1,1,2,2-cyclopropanetetracarbonitrile; 1,1,2,2-tetracyano-3-methyl-3-propylcyclopropane. Grades: ≥99% by HPLC. CAS No. 13017-69-1. Molecular formula: C11H10N4. Mole weight: 198.22. | |
| CCG215022 | CCG215022 is a G protein-coupled receptor kinases (GRKs) inhibitor (IC50s= 0.15±0.07 μM, 0.38±0.06 μM and 3.9±1 μM for GRK2, GRK5 and GRK1, respectively), with good selectivity against other closely related kinases such as GRK1 and PKA. Synonyms: 4-(4-fluoro-3-((pyridin-2-ylmethyl)carbamoyl)phenyl)-N-(1H-indazol-5-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide; CCG215022; CCG 215022; CCG-215022. CAS No. 1813527-81-9. Molecular formula: C26H22FN7O3. Mole weight: 499.5. | |
| CCG 232601 | CCG 232601 is a selective and orally bioactive inhibitor of the Rho/MRTF/SRF signaling pathway (IC50 value of 0.55 μM (SRE.L assay)) as a potential antifibrotic therapeutic for systemic scleroderma. CCG-232601 inhibits the development of bleomycin-induced dermal fibrosis in mice when administered orally. Synonyms: N-(4-chlorophenyl)-5,5-difluoro-1-(3-pyridin-4-ylbenzoyl)piperidine-3-carboxamide; CCG-232601; CCG 232601; CCG232601. Grades: 99%. CAS No. 1922099-21-5. Molecular formula: C24H20ClF2N3O2. Mole weight: 455.88. | |
| CCG-63802 | CCG-63802 is a reversible inhibitor of regulator of G-protein signaling (RGS) protein. It is selective amongst RGS proteins, with greatest potency at RGS4. It also inhibits GTPase accelerating protein activity of RGS4, blocks its interaction with Gαo, and retains activity under reducing conditions. Synonyms: CCG-4986; CCG 4986; CCG4986. Grades: >98%. CAS No. 620112-78-9. Molecular formula: C26H18N4O2S. Mole weight: 450.51. | |
| CCG-63808 | CCG-63808 is a reversible inhibitor of regulator of G-protein signaling (RGS) proteins. Synonyms: CCG-63808; CCG 63808; CCG63808. Grades: >98%. CAS No. 620113-73-7. Molecular formula: C25H15FN4O2S. Mole weight: 454.48. | |
| CCK (26-30) (sulfated) | Cholecystokinin (CCK) is a neuropeptide and gut hormone that regulates pancreatic enzyme secretion and gastrointestinal motility, and acts as a satiety signal. CCK (26-30) is an N-terminal fragment of CCK, the sulfated form of CCK (26-30) inhibits binding of [125I]CCK-33 to guinea pig cortical membranes by 10% at 0.1 mM. Synonyms: N-Acetyl cholecystokinin (26-30) (sulfated). Grades: ≥95%. CAS No. 89911-69-3. Molecular formula: C33H41N7O12S2. Mole weight: 791.85. | |
| CCK (26-31) (sulfated) | Cholecystokinin (CCK) is a neuropeptide and gut hormone that regulates pancreatic enzyme secretion and gastrointestinal motility, and acts as a satiety signal. CCK (26-31) is an N-terminal fragment of CCK, the sulfated form of CCK (26-31) inhibits binding of [125I]CCK-33 to guinea pig cortical membranes by 21% at 0.1 mM. Synonyms: N-Acetyl cholecystokinin (26-31) (sulfated). Grades: ≥95%. CAS No. 89911-65-9. Molecular formula: C38H50N8O13S3. Mole weight: 923.05. | |
| CCK (27-33) (non-sulfated) | Cholecystokinin (CCK) is a neuropeptide and gut hormone that regulates pancreatic enzyme secretion and gastrointestinal motility, and acts as a satiety signal. CCK (27-33) is a C-terminal fragment of CCK. Non-sulfated CCK (27-33) inhibits binding of [3H]naloxone in rat cerebellum membranes with IC50 of 4 μM and inhibits electrically-stimulated contraction of isolated guinea pig ileum with IC50 of 17 μM. Synonyms: Cholecystokinin (27-33) (non-sulfated). Grades: ≥95%. CAS No. 47910-79-2. Molecular formula: C45H57N9O10S2. Mole weight: 948.12. | |
| CCMQ | CCMQ is an inhibitor of homoquinolinic acid binding to non-NMDA sensitive sites. It is combined with [3H]-homoquinolinic acid to characterize NR2B-containing NMDA receptors. Synonyms: 2-Carboxy-3-carboxymethylquinoline. CAS No. 132623-44-0. Molecular formula: C12H9NO4. Mole weight: 231.21. | |
| CCR1 antagonist | CCR1 antagonist is a chemokine CCR1 antagonist. It is used for the treatment of chronic obstructive pulmonary disease. Uses: Ccr1 antagonist is used for the treatment of chronic obstructive pulmonary disease. Synonyms: AZD-4818; AZD 4818; AZD4818. (S)-2-(2-chloro-5-(3-(5-chloro-3H-spiro[benzofuran-2,4'-piperidin]-1'-yl)-2-hydroxypropoxy)-4-(methylcarbamoyl)phenoxy)-;2-[2-Chloro-5-[(2S)-3-(5-chlorospiro[3H-1-benzofuran-2,4'-piperidine]-1'-yl)-2-hydroxypropoxy]-4-(methylcarbamoyl)phenoxy]-2-methylpropanoic acid. Grades: >98 %. CAS No. 1003566-93-5. Molecular formula: C27H32Cl2N2O7. Mole weight: 567.46. | |
| CCT007093 | CCT007093 is a potent PPM1D inhibitor or WIP1 inhibitor that selectively reduces viability of human tumour cell lines. Synonyms: CCT007093; CCT-007093; CCT 007093. Grades: 0.98. CAS No. 176957-55-4. Molecular formula: C15H12OS2. Mole weight: 272.38. | |
| CDDU-Me | CDDU-Me is an activator of the Nrf2 pathway, which induces the expression of cytoprotective genes regulated by Nrf-2 in vivo. It has anti-inflammatory, anti-tumor and cell protection properties. Synonyms: AC-31539. CAS No. 1616932-17-2. Molecular formula: C32H43NO4. Mole weight: 505.7. | |
| C-DIM12 | C-DIM12 is a novel synthetic activator of Nurr1. C-DIM12 induces dopaminergic gene expression and protects against 6-hydroxydopamine neurotoxicity in vitro. Synonyms: C-DIM12; C-DIM 12; C-DIM-12. Grades: 98%. CAS No. 178946-89-9. Molecular formula: C23H17ClN2. Mole weight: 356.85. | |
| CDN 1163 | CDN 1163 is an allosteric activator of sarco/endoplasmic reticulum Ca2+-ATPase (SERCA2), increasing Ca2+-ATPase activity and Ca2+ uptake by ER microsomes from obese mice. It reduces fasting glucose levels and adipose tissue weight, and increases energy expenditure in ob/ob mice. CDN 1163 has the potential to treat type-2 diabetes and metabolic dysfunction. Synonyms: CDN-1163; CDN 1163; CDN1163; 4-(1-Methylethoxy)-N-(2-methyl-8-quinolinyl)benzamide; 4-Isopropoxy-N-(2-methylquinolin-8-yl)benzamide. Grades: ≥98% by HPLC. CAS No. 892711-75-0. Molecular formula: C20H20N2O2. Mole weight: 320.38. | |
| CDP 840 hydrochloride | CDP 840 hydrochloride is a potent and selective inhibitor of phosphodiesterase 4 (PDE4) (IC50 = 12 nM). It competitively inhibits all PDE4 isoenzymes. Synonyms: CDP840; CDP-840; CDP 840; CDP840 HCl; CDP840HCl. 4-[(2R)-2-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-phenylethyl]-pyridine hydrochloride. Grades: ≥98% by HPLC. CAS No. 162542-90-7. Molecular formula: C25H27NO2.HCl. Mole weight: 409.95. | |
| CDy9 | CDy9, a pyrrolodiazaborinine derivative, has been found to be a fluorescent probe and could be used to detect and isolate intact stem cells. Synonyms: CDy9; CDy-9; CDy 9; (E)-2-chloro-N-(2-(5,5-difluoro-3-(2-hydroxy-5-methylstyryl)-1-methyl-5H-4l4,5l4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-10-yl)ethyl)acetamide. Grades: 98%. CAS No. 1800205-57-5. Molecular formula: C23H23BClF2N3O2. Mole weight: 457.71. | |
| CE3F4 | CE3F4 is a noncompetitive Epac1 inhibitor that inhibits Epac-induced Rap activation and prevents isoprenaline-induced autophagy flux in cardiomyocytes. It has no effect on PKA activity in the presence of cAMP. Synonyms: CE3F4; CE-3-F-4; CE 3 F 4; CE-3F4; CE 3F4; 5,7-Dibromo-6-fluoro-3,4-dihydro-2-methyl-1(2H)-quinolinecarboxaldehyde. Grades: ≥98% by HPLC. CAS No. 143703-25-7. Molecular formula: C11H10Br2FNO. Mole weight: 351.01. | |
| Cebranopadol | Cebranopadol is a novel first-in-class compound with potent agonist activity on opioid receptor like-1(ORL-1) and the well established mu opioid receptor. It showed antinociceptive and antihypertensive effects in a variety of different animal models of pain, suggesting its potential use for the treatment of chronic pain states. Synonyms: GRT6005; GRT 6005; GRT-6005; 6-fluoro-N,N-dimethyl-1'-phenylspiro[4,9-dihydro-3H-pyrano[3,4-b]indole-1,4'-cyclohexane]-1'-amine. Grades: >98%. CAS No. 863513-91-1. Molecular formula: C24H27FN2O. Mole weight: 378.491. | |
| Ceefourin 1 | Ceefourin 1 has been found to be a selective MRP4 inhibitor (IC50 = 2.6 μM). Synonyms: Ceefourin-1; Ceefourin 1; Ceefourin1; 5-[(2-Benzothiazolylthio)methyl]-2,4-dihydro-4-methyl-3H-1,2,4-triazole-3-thione. Grades: ≥98% by HPLC. CAS No. 315702-40-0. Molecular formula: C11H10N4S3. Mole weight: 294.42. | |
| Cefazolin EP Impurity G | An impurity of Cefazolin, an antibiotic used for the treatment of bacterial infections. Synonyms: Cefazolin Lactone; Cefazolin Sodium Impurity G. CAS No. 1172998-53-6. Molecular formula: C11H10N6O4S. Mole weight: 322.3. | |
| Cefazolin Impurity C | an impurity of Cefazolin. Synonyms: (6R,7R)-3-Methyl-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-5-thia-1-azabicyclo [4.2.0]oct-2-ene-2-carboxylic acid. Grades: > 95%. CAS No. 56842-77-4. Molecular formula: C11H12N6O4S. Mole weight: 324.32. | |
| Cefazolin Impurity D | An impurity of Cefazolin, an antibiotic used for the treatment of bacterial infections. Synonyms: 5-Thia-1-azabicyclo[4.2.0]?oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)?methyl]?-8-oxo-7-[[2-(1H-tetrazol-1-yl)?acetyl]?amino]?-, (6R,?7R)?-. Grades: > 95%. CAS No. 32510-61-5. Molecular formula: C13H14N6O6S. Mole weight: 382.36. | |
| Cefmenoxime hydrochloride | Cefmenoxime hydrochloride is a third-generation cephalosporin antibiotic with strong antimicrobial activities against Streptococcus pneumoniae, Haemophilus influenzae and Moraxella subgenus Branhamella catarrhalis that were 3 major aerobic bacteria from sinusitis. It is administered intravenously or intramuscularly. It is active against most common gram-positive and gram-negative microorganisms, It is a potent inhibitor of Enterobacteriaceae and is highly resistant to hydrolysis by beta-lactamases. It has a high rate of efficacy in many types of infection and to date no severe side effects have been noted. Uses: Cefmenoxime hydrochloride is active against most common gram-positive and gram-negative microorganisms, it is a potent inhibitor of enterobacteriaceae and is highly resistant to hydrolysis by beta-lactamases. Synonyms: Cefmenoxime Hydrochloride; SCE 1365 hydrochloride; AB 50912 hemihydrochloride; EINECS 278-299-4; Cefmenoxime hemihydrochloride; Cefmenoxime HCl; SCE1365; Hydrochloride, Cefmenoxime; SCE 1365; SCE-1365;VA10523; A838501;7-[[2-(2-amino-4-thiazolyl)-2-methoxyimino-1-oxoethyl]amino]-3-[[(1-methyl-5-tetrazolyl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrochloride;8-[2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino-acetyl]amino-4-[(1-methyltetrazol-5-yl)sulfanylmethyl]-7-oxo-2-thia-6-azabicyclo[4.2.0]oct-4-ene-5-carboxylic acid hydrochloride (2:1);Cefmenoxime hemihydrochloride;SCE-1365 hemihydrochloride. Grades: 98%. CAS No. 75738-58-8. Molecular formula: C32H35ClN18O10S6. Mole weight: 1059.58. | |
| Cefovecin sodium | Cefovecin Sodium is an antibiotic of the cephalosporin class. It is used for the treatment of skin infections caused by Pasturella multocida in cats, and Staphylococcus intermedius/S. canis in dogs. Cefovecin Sodium is the first single-dose injectable antibiotic for dogs and cats. Uses: The treatment of skin conditions in dogs and cats. Synonyms: UNII-DL8Q24959P; DL8Q24959P; C13142. Grades: 95%. CAS No. 141195-77-9. Molecular formula: C17H18N5NaO6S2. Mole weight: 475.47. | |
| Cefprozil EP Impurity G | | |
| Cefprozil EP Impurity I | | |
| Cefprozil Monohydrate EP Impurity E | An impurity of Cefprozil, a cephalosporin antibiotic used to treat a variety of bacterial infections. Synonyms: O-Acyl cefprozil (USP); (Z)-O-((2R)-2-amino-2-(4-hydroxyphenyl)acetyl)cefprozil. Grades: 90%. Molecular formula: C26H26N4O7S. Mole weight: 538.57. | |
| Ceftaroline fosamil acetate | Ceftaroline fosamil, also known as TAK 599, is a cephalosporin antibiotic with activity against methicillin-resistant Staphylococcus aureus (MRSA) and Gram-positive bacteria. Ceftaroline fosamil is a prodrug of the cephalosporin antibiotic T-91825. Uses: Beta lactam antibiotics. Synonyms: Pyridinium, 4-[2-[[(6R,7R)-2-carboxy-7-[[(2Z)-2-(ethoxyimino)-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]thio]-4-thiazolyl]-1-methyl-, acetate (1:1); Pyridinium, 4-[2-[[(6R,7R)-2-carboxy-7-[[(2Z)-(ethoxyimino)[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]thio]-4-thiazolyl]-1-methyl-, acetate; Ceftaroline; Ceftaroline fosamil; PPI 0903; TAK 599; Teflaro; Zinforo. Grades: ≥95%. CAS No. 400827-46-5. Molecular formula: C24H25N8O10PS4. Mole weight: 744.72. | |
| Ceftazidime Impurity A | An impurity of Ceftazidime, an antibiotic for certain infection treatment. Synonyms: 1-[[(6R,7R)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-en-3-yl]methyl]pyridinium; Δ-2-Ceftazidime; Ceftazidime Impurity A (EP). Grades: > 95%. CAS No. 1000980-60-8. Molecular formula: C22H22N6O7S2. Mole weight: 546.58. | |
| Ceftazidime Impurity G | An impurity of ceftazidime, an antibiotic used for certain infection treatment. Synonyms: 2-[[[(1Z)-1-(2-Aminothiazol-4-yl)-2-[(oxoethyl)amino]-2-oxoethylidene] amino] oxy]-2-methylpropanoic acid. Grades: > 95%. CAS No. 194241-83-3. Molecular formula: C11H14N4O5S. Mole weight: 314.32. | |
| Ceftazidime Impurity H | An impurity of ceftazidime, an antibiotic used for certain infection treatment. Synonyms: Methyl ceftazidime; Ceftazidime Methyl Ester. Grades: > 95%. CAS No. 1354396-23-8. Molecular formula: C23H24N6O7S2. Mole weight: 560.61. | |
| Ceftazidime Intermediate | An impurity of ceftazidime, an antibiotic used for certain infection treatment. Synonyms: taem; (Z)-tert-Butyl 2-(((1-(2-aminothiazol-4-yl)-2-(benzo[d]thiazol-2-ylthio)-2-oxoethylidene)amino)oxy)-2-methylpropanoate. Grades: > 95%. CAS No. 158183-05-2. Molecular formula: C20H22N4O4S3. Mole weight: 478.61. | |
| Ceftibuten Dihydrate | Dihydrate form of Ceftibuten which is one of the third-generation cephalosporin antibiotics. Uses: Dihydrate form of ceftibuten which is one of the third-generation cephalosporin antibiotics. Synonyms: ceftibuten dihydrate;(+)-(6r,7r)-7-[2-(2-amino-1,3-thiazol-4-yl)-4-carboxy-2-butenamide]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid dihydrate;Sch-39720;(+)-(6R,7R)-7-[2-(2-Amino-1,3-thiazol-4-yl)-4-carboxy-2-butenamide]-8-oxo-5-thia-1-az. Grades: 95%. CAS No. 118081-34-8. Molecular formula: C15H14N4O6S2.2(H2O). Mole weight: 446.45. | |
| Ceftobiprole | Ceftobiprole is a cephalosporin prodrug with potent bactericidal activity against methicillin-resistant MRSA and penicillin-resistant Streptococcus pneumoniae (PRSP). Synonyms: (6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-ylidene)-2-nitrosoacetyl]amino]-8-oxo-3-[(E)-[2-oxo-1-[(3R)-pyrrolidin-3-yl]pyrrolidin-3-ylidene]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; BAL 9141; BAL9141. Grades: >95%. CAS No. 209467-52-7. Molecular formula: C20H22N8O6S2. Mole weight: 534.57. | |
| Ceftobiprole medocaril sodium | Ceftobiprole medocaril sodium is a water-soluble prodrug ceftobiprole, a 5th-generation cephalosporin for the treatment of hospital-acquired pneumonia (excluding ventilator-associated pneumonia) and community-acquired pneumonia. Ceftobiprole binds to penicillin-binding proteins (PBPs) and inhibits their transpeptidase activity. Synonyms: Ceftobiprole medocaril; BAL5788; BAL-5788. CAS No. 252188-71-9. Molecular formula: C26H25N8NaO11S2. Mole weight: 712.6. | |
| Ceftriaxone Impurity E | An impurity of Ceftriaxone, a cephalosporin antibiotic for the treatment of various bacterial infections. Synonyms: (6R,7R)-7-Amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid. Grades: > 95%. CAS No. 58909-56-1. Molecular formula: C12H13N5O5S2. Mole weight: 371.4. | |
| Cefuroxime Axetil Impurity E | (αZ)-α-(Methoxyimino)-N-[(5aR,6R)-1,4,5a,6-tetrahydro-1,7-dioxo-3H,7H-azeto[2,1-b]furo[3,4-d][1,3]thiazin-6-yl]-2-furanacetamide is an impurity of Cefuroxime Axetil, the 1-(acetyloxy) ethyl ester of Cefuroxime , an injectable second generation cephalosporin with an excellent antibacterial activity. Synonyms: (αZ)-α-(Methoxyimino)-N-[(5aR,6R)-1,4,5a,6-tetrahydro-1,7-dioxo-3H,7H-azeto[2,1-b]furo[3,4-d][1,3]thiazin-6-yl]-2-furanacetamide. Grades: > 95%. CAS No. 947723-87-7. Molecular formula: C15H13N3O6S. Mole weight: 363.35. | |
| Celecoxib | Celecoxib is a COX-2 inhibitor and nonsteroidal anti-inflammatory drug (NSAID) used to treat the pain and inflammation in osteoarthritis, acute pain in adults, rheumatoid arthritis, ankylosing spondylitis, painful menstruation, and juvenile rheumatoid arthritis. Uses: Cyclooxygenase 2 inhibitors. Synonyms: Celebra; Celebrex; SC 58635; Benzenesulfonamide, 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-; 4-[5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide; 4-[5-(p-Tolyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide; Celecox; Celocoxib; Eurocox; Medicoxib; Onsenal; Xilebao; YM 177. Grades: ≥95%. CAS No. 169590-42-5. Molecular formula: C17H14F3N3O2S. Mole weight: 381.37. | |
| Celecoxib Impurity 2 | An impurity of celecoxib, a cyclooxygenase 2 inhibitor. Synonyms: 1H-Pyrazole, 5-(4-methylphenyl)?-3-(trifluoromethyl)?-; 5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazole; 5-(p-Tolyl)-3-(trifluoromethyl)-1H-pyrazole; 5-(4-Methylphenyl)-3-trifluoromethyl-1H-pyrazole; Celecoxib Impurity H. Grades: > 95%. CAS No. 948293-46-7. Molecular formula: C11H9F3N2. Mole weight: 226.2. | |
| Celecoxib Impurity A | Cas No. 170570-01-1. | |
| Celecoxib Impurity C | Cas No. 170569-99-0. | |
| Celecoxib Related Compound B | Cas No. 331943-04-5. | |
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