BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| CK 869 | CK 869 has been found to inhibit actin polymerization as well as human and bovine actin-related protein 2/3 (Arp2/3) complex. Synonyms: CK-869; CK 869; CK869; CK-0157869; CK 0157869; CK0157869; 2-(3-Bromophenyl)-3-(2,4-dimethoxyphenyl)-4-thiazolidinone. Grades: ≥98% by HPLC. CAS No. 388592-44-7. Molecular formula: C17H16BrNO3S. Mole weight: 394.28. |  |
| CL075 | CL075 is a thiazoloquinolone derivative that stimulates TLR8 in human peripheral blood mononuclear cells. Uses: Toll-like receptor agonists. Synonyms: CL 075; CL-075; Thiazolo[4,5-c]quinolin-4-amine, 2-propyl-; 2-Propylthiazolo[4,5-c]quinolin-4-amine; 3M 002; 3M-002; 3M002. Grades: ≥95%. CAS No. 256922-53-9. Molecular formula: C13H13N3S. Mole weight: 243.33. | |
| CL097 | CL097 is a human TLR7/8 and mouse TLR7 agonist. Synonyms: CL 097; CL-097; 3H-Imidazo[4,5-c]quinolin-4-amine, 2-(ethoxymethyl)-; 2-(Ethoxymethyl)-1H-imidazo[4,5-C]quinolin-4-amine. Grades: ≥95%. CAS No. 1026249-18-2. Molecular formula: C13H14N40. Mole weight: 242.28. | |
| CL264 | CL264 is a small-molecule agonist of TLR7. Synonyms: Glycine, N-[4-[[6-amino-2-(butylamino)-7,8-dihydro-8-oxo-9H-purin-9-yl]methyl]benzoyl]-; N-[4-[[6-Amino-2-(butylamino)-7,8-dihydro-8-oxo-9H-purin-9-yl]methyl]benzoyl]glycine; CL 246; CL 264; CL-264; (4-((6-amino-2-(butylamino)-8-oxo-7,8-dihydro-9H-purin-9-yl)methyl)benzoyl)glycine. Grades: ≥95%. CAS No. 1510712-69-2. Molecular formula: C47H73N13O7S. Mole weight: 413.43. | |
| CL307 | CL307 is an agonist of TLR7. Synonyms: Benzamide, 4-[[6-amino-2- (butylamino) -7, 8-dihydro-8-oxo-9H-purin-9-yl]methyl]-N-[2-[[3-[[4-[ (3-aminopropyl) amino]butyl]amino]propyl]amino]-2-oxoethyl]-; CL 307; CL-307; N1-glycinyl[4-((6-amino-2-(butylamino)-8-hydroxy-9H-purin-9-yl)methyl)benzoyl]spermine; 4- ( (6-amino-2- (butylamino) -8-oxo-7, 8-dihydro-9H-purin-9-yl) methyl) -N- (2- ( (3- ( (4- ( (3-aminopropyl) amino) butyl) amino) propyl) amino) -2-oxoethyl) benzamide; 4-[[6-Amino-2- (butylamino) -7, 8-dihydro-8-oxo-9H-purin-9-yl]methyl]-N-[2-[[3-[[4-[ (3-aminopropyl) amino]butyl]amino]propyl]amino]-2-oxoethyl]benzamide. Grades: ≥95%. CAS No. 1548551-79-6. Molecular formula: C29H47N11O3. Mole weight: 597.76. | |
| CL 43356 | CL 43356 is a synthetic bio-active chemical. Uses: A synthetic bio-active chemical. Synonyms: CL 43356; CL 43356; CL 43356; CL-43,356; O,O-dimethyl 1,3-dithiolan-2-ylidenephosphoramidothioate;N-dimethoxyphosphinothioyl-1,3-dithiolan-2-imine. Grades: ≥98%. CAS No. 3572-55-2. Molecular formula: C5H10NO2PS3. Mole weight: 242.96. | |
| Cladribine | 2-Chloro-2'-deoxyadenosine is an analog of adenosine that is resistant to both proliferating and non-dividing lymphocytes (IC50 = 45 nM). When phosphorylated, 2-Chloro-2'-deoxyadenosine accumulates in cells and inhibits ribonucleotide reductase. Synonyms: 2-Chloro-2'-deoxyadenosine; Leustatine; 2-CdA; 9-(2'-Deoxy-β-D-ribofuranosyl)-2-chloro-adenine; 2-Chlorodeoxyadenosine; (2R,3S,5R)-5-(6-amino-2-chloro-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol; 2-chloro-6-amino-9-(2-deoxy-beta-D-erythro-pentofuranosyl)purine. Grades: ≥95%. CAS No. 4291-63-8. Molecular formula: C10H12ClN5O3. Mole weight: 285.69. | |
| Cladribine Related Compound A | 2-Methoxy-2'-deoxyadenosine is an impurity in the synthesis of Cladribine, a substituted purine nucleoside with antileukemic activity. Synonyms: 2-Methoxy-2'-deoxyadenosine; 2-Methoxy-6-amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)purine; 9-(2-Deoxy-β-D-ribofuranosyl)-2-methoxyadenine; 2'-Deoxy-2-methoxyadenosine; (2R,3S,5R)-5-(6-Amino-2-methoxy-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol; 2'-Deoxyspongosine. Grades: ≥95%. CAS No. 24757-70-8. Molecular formula: C11H15N5O4. Mole weight: 281.27. | |
| Cl-amidine | Cl-amidine is an inhibitor of irreversible protein pan-peptidylarginine deiminase (PAD) with IC50 values of 5.9 ± 0.3 μM, 0.8 ± 0.3 μM, 6.2 ± 1.0 μM for PAD4, PAD1 and PAD3, respectively. It irreversibly inactivates all four PAD subtypes by covalently modifying an active site cysteine that is important for its catalytic activity. Synonyms: N-[(1S)-1-(aminocarbonyl)-4-[(2-chloro-1-iminoethyl)amino]butyl]-benzamide. Grades: ≥95%. CAS No. 1043444-18-3. Molecular formula: C14H19ClN4O2·C2HF3O2. Mole weight: 424.8. | |
| Cl-Amidine hydrochloride | Cl-amidine is an inhibitor of irreversible protein pan-peptidylarginine deiminase (PAD) with IC50 values of 5.9 ± 0.3 μM, 0.8 ± 0.3 μM, 6.2 ± 1.0 μM for PAD4, PAD1 and PAD3, respectively. It irreversibly inactivates all four PAD subtypes by covalently modifying an active site cysteine that is important for its catalytic activity. Synonyms: N-[(1S)-1-(aminocarbonyl)-4-[(2-chloro-1-iminoethyl)amino]butyl]-benzamide monohydrochloride. Grades: ≥95%. CAS No. 1373232-26-8. Molecular formula: C14H19ClN4O2·HCl. Mole weight: 347.24. | |
| Clamoxyquin Hydrochloride | Clamoxyquine, as the pamoate or hydrochloride salt, is an antiamebic and antidiarrheal drug used as a veterinary medicine to treat salmonids for infection with the myxozoan parasite Myxobolus cerebralis. Uses: Antiamebic and antidiarrheal. Synonyms: 5-chloro-7-[[3- (diethylamino) propylamino]methyl]quinolin-8-ol; dihydrochloride. Grades: ≥98%. CAS No. 4724-59-8. Molecular formula: C17H26Cl3N3O. Mole weight: 394.76. | |
| Clavulanate potassium | Cas No. 61177-45-5. | |
| Clemaphenol A | Clemaphenol A is a lignan found in the Cynanchum auriculatum. Synonyms: rel-3,3'-[(1R,3aS,4R,6aS)-Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis[6-methoxyphenol]. Grades: >98%. CAS No. 362606-60-8. Molecular formula: C20H22O6. Mole weight: 358.39. | |
| Clematichinenoside AR | Clematichinenoside AR is a triterpenoid saponin. Synonyms: (-)-Platycoside G1; Deapi-platycoside E; Deapioplatycoside E. Grades: >98%. CAS No. 761425-93-8. Molecular formula: C64H104O34. Mole weight: 1417.5. | |
| Clematichinenoside C | Clematichinenoside C is a triterpenoid saponin isolated from the roots of Clematis chinensis. Synonyms: Olean-12-en-28-oic acid, 3-[(O-β-D-glucopyranosyl-(1?4)-O-β-D-ribopyranosyl-(1?3)-O-6-deoxy-α-L-mannopyranosyl-(1?2)-α-L-arabinopyranosyl)oxy]-, O-6-deoxy-α-L-mannopyranosyl-(1?4)-O-β-D-glucopyranosyl. Grades: >98%. CAS No. 177912-24-2. Molecular formula: C70H114O34. Mole weight: 1499.65. | |
| Clematiunicinoside E | Clematiunicinoside E is a triterpenoid saponin isolated from the roots of Clematis uncinata. Synonyms: Clematomandshurica saponin C. Grades: >98%. CAS No. 916649-92-8. Molecular formula: C76H124O39. Mole weight: 1661.77. | |
| Clenbuterol Impurity E | Clenbuterol Impurity E is an impurity of Clenbuterol and is used as a reagent in the synthesis of pyrazolopyridine derivatives as inhibitors of phosphodiesterase-4 (PDE-IV) and production of tumor necrosis factor-α (TNF-α). Synonyms: 4-Amino-3,5-dichlorophenacylbromide; 1-(4-Amino-3,5-dichlorophenyl)-2-bromoethan-1-one. Grades: 95%. CAS No. 37148-47-3. Molecular formula: C8H6BrCl2NO. Mole weight: 282.95. | |
| Clenpirin | Clenpirin, an imino-pyrolidine, has been developed as an acaricide for the control of Boophilus. Synonyms: 1-butyl-N-(3,4-dichlorophenyl)pyrrolidin-2-imine; Clenpirin; BRN 1540697; Clempirina; Clempirina [INN-Spanish]; UNII-PFM79PGI92; Clenpirin; Clenpirine; Clenpirine [INN-French;] Clenpirinum; Clenpirinum [INN-Latin]; Clenpyrin; EINECS 248-190-6. Grades: >98%. CAS No. 27050-41-5. Molecular formula: C14H18Cl2N2. Mole weight: 285.21. | |
| Cletoquine | Cletoquine is a metabolite of Hydroxychloroquine, which is an antimalarial. Synonyms: 2-[[4-[(7-Chloro-4-quinolyl)amino]pentyl]amino]ethanol; (±)-Desethylhydroxychloroquine; Desethyl Hydroxy Chloroquine. Grades: >95%. CAS No. 4298-15-1. Molecular formula: C16H22ClN3O. Mole weight: 307.83. | |
| Clevidipine Impurity 4 | Clevidipine Impurity 4 is an impurity of Clevidipine, a therapeutic drug primarily for treating hypertension and treating arteriosclerosis. Synonyms: 4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3-pyridinecarboxylic acid methyl ester; H 168/79; methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3-carboxylate. Grades: > 95%. CAS No. 253597-20-5. Molecular formula: C15H15Cl2NO2. Mole weight: 312.2. | |
| Clevidipine Impurity 6 | Clevidipine Impurity 6 is an impurity of clevidipine, a medication used to treat high blood pressure. Synonyms: 4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid. Grades: > 95%. CAS No. 138279-32-0. Molecular formula: C15H13Cl2NO4. Mole weight: 342.18. | |
| Clinafloxacin hydrochloride | Clinafloxacin hydrochloride is a novel fluoroquinolone antimicrobial agent as a potent intraphagocytic bactericidal agent. It displays broad-spectrum antibacterial activity against gram-negative, gram-positive and anaerobic pathogens by inhibiting the bacterial regulatory enzyme DNA gyrase with IC50 value of 0.92 μg/ml and topoisomerase IV with IC50 value of 1.62 μg/ml. It has been studied for parenteral and oral administration in subjects with serious infections. Uses: Clinafloxacin hydrochloride is used as a potent intraphagocytic bactericidal agent. Synonyms: 7-(3-Amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid hydrochloride;7-(3-Aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-keto-quinoline-3-carboxylic acid hydrochloride;7-(3-Azanylpyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-quinoline-3-Carboxylic acid hydrochloride;3-Quinolinecarboxylic acid, 7-(3-aMino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-, Monohydrochloride;CI-960 HCl;CI960 HCl. Grades: ≥99%. CAS No. 105956-99-8. Molecular formula: C17H18Cl2FN3O3. Mole weight: 402.25. | |
| Clindamycin 3-Phosphate | Clindamycin 3-Phosphate is an impurity of Clindamycin, an antibiotic medication used for the treatment of bacterial infections. Synonyms: (2R,3S,4S,5R,6R)-2-((1S,2R)ylpyrrolidineyl)-3,5-dihydroxy-6-(methylthio)tetrahydro-2H-pyran-4-yl dihydrogen phosphate. Grades: 90%. CAS No. 28708-34-1. Molecular formula: C18H34ClN2O8PS. Mole weight: 504.96. | |
| Clioxanide | Clioxanide is an anthelmintic agent. Uses: Anthelmintic agent. Synonyms: Clioxanide; Tremerad; SYD 230; SYD230; SYD-230; Clioxanidum [INN-Latin]; Clioxanida [INN-Spanish]; SYD-230; EINECS 238-414-0;2-(4-Chlorphenylcarbamoyl)-4,6-diodphenyl acetat. Grades: 98%. CAS No. 14437-41-3. Molecular formula: C15H10ClI2NO3. Mole weight: 541.50. | |
| Clocortolone Pivalate | Clocortolone Pivalate is a Corticosteroid Hormone Receptor Agonist. It is used for the treatment of dermatitis and is considered a medium-strength corticosteroid. It is unusual among steroids in that it contains a chlorine atom and a fluorine atom. Uses: Clocortolone pivalate is a corticosteroid hormone receptor agonist. Synonyms: 9-Chloro-6α-fluoro-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-pivalate, Clocortolone 21-pivalate; (6α,11β,16α)-9-Chloro-21-(2,2-dimethyl-1-oxopropoxy)-6-fluoro-11-hydroxy-16-methypregna-1,4-diene-3,20-dione; CL 68; Clocortolone trimethylacetat. Grades: > 95%. CAS No. 34097-16-0. Molecular formula: C27H36ClFO5. Mole weight: 495.04. | |
| Clofentezine | Clofentezine is an active substance of plant protection product used as pesticide, acaricide. It belongs to the chemical family of quinoxalines. It is used in agriculture for the protection of ornamentals, food and non-food crops in the field. It has sublethal effects on life-table parameters of Tetranychus urticae Koch females. Uses: Clofentezine is used as a pesticide, acaricide. it is used in agriculture for the protection of ornamentals, food and non-food crops in the field. Synonyms: NC 21314; 3, 6-Bis(2-chlorophenyl)-1, 2, 4, 5-tetrazine; Acaristop; Apollo; Bisclofentezin. Grades: 98%. CAS No. 74115-24-5. Molecular formula: C14H8Cl2N4. Mole weight: 303.15. | |
| Clonidine | Clonidine is an α2-Adrenergic agonist for neuropathic pain. Uses: α2 adrenergic agonist. Synonyms: CLONIDINE BASE;Clonidine (base and/or unspecified salts);CLONIDINE (200 MG);1H-Imidazol-2-amine, N-(2,6-dichlorophenyl)-4,5-dihydro-;2-((2,6-dichlorophenyl)amino)-2-imidazoline;2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2);2-(2,6-dichloroanilino)-2-i. Grades: ≥98%. CAS No. 4205-90-7. Molecular formula: C9H9Cl2N3. Mole weight: 230.09. | |
| Clopidogrel Impurity D | Clopidogrel Carboxylic Acid [Methyl (R)-o-chloromandelate] Ester is an impurity of Clopidogrel, an antithrombotic agent. Synonyms: Clopidogrel Carboxylic Acid [Methyl (R)-o-chloromandelate] Ester. Grades: > 95%. CAS No. 1421283-60-4. Molecular formula: C24H21Cl2NO4S. Mole weight: 490.4. | |
| Clopidogrel Impurity K | An impurity of Clopidogrel, an antiplatelet medication used to reduce the risk of heart disease and stroke in those at high risk. Synonyms: (+/-)-RAC-2-(2-CHLOROPHENYL)-(6,7-DIHYDRO-4H-THIENO[3,2-C]PYRIDIN-5-YL)ACETONITRILE. CAS No. 444728-11-4. Molecular formula: C15H13ClN2S. Mole weight: 288.8. | |
| Clopidogrel Related Compound A | Cas No. 144457-28-3. | |
| Clopidogrel Related Compound B | Clopidogrel Related Compound B is a tetrahydrothienopyridine as inhibitor of angiogenesis. Synonyms: Methyl (+/-)-(o-Chlorophenyl)-4,5-dihydrothieno[3,2-c]pyridine-6(7H)acetate Hydrochloride; α-(2-Chlorophenyl)-4,7-dihydro-thieno[2,3-c]pyridine-6(5H)acetic Acid Methyl Ester Hydrochloride. Grades: > 95%. CAS No. 144750-52-7. Molecular formula: C16H17Cl2NO2S. Mole weight: 358.28. | |
| Clopidogrel Related Compound C (R-Clopidogrel) | R-(-)-Clopidogrel Hydrogen Sulfate is used as an antithrombotic. Synonyms: R-(-)-Clopidogrel Hydrogen Sulfate; (R)-(-)-Methyl 2-(2-Chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate Hydrogen Sulfate; (R)-Clopidogrel Bisulfate; SR 25989C. Grades: > 95%. CAS No. 120202-71-3. Molecular formula: C16H18ClNO6S2. Mole weight: 419.9. | |
| (+)-Cloprostenol isopropyl ester | (+)-Cloprostenol isopropyl ester is a derivative of cloprostenol which has been found to be a FP receptor agonist as well as a luteolytic agent and could be used commonly as a veterinary drug for its effect in terminating pregnancy. Synonyms: (+)-Cloprostenol isopropyl ester; HE113833; LP014937; (5Z)-7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-Chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester; [1R-[1α(Z), 2β(1E, 3R*), 3α, 5α]]-7-[2-[4-(3-Chlorophenoxy)-3-hy. Grades: 98%. CAS No. 157283-66-4. Molecular formula: C25H35ClO6. Mole weight: 466.99. | |
| Cloquintocet-mexyl | Cloquintocet-mexyl is a herbicide. It is used to control coarse annual grass of the family poaceae (gramineae). lt was developed by the swiss ciba geigy in the 1980s and the patent has expired. Uses: Cloquintocet-mexyl is a herbicide. Synonyms: 1-Methylhexyl (5-chloroquinolin-8-yloxy)acetate;Cloquintocet-1 heptan-2-yl 2-(5-chloroquinolin-8-yl)oxyacetate;Acetic acid,[(5-chloro-8-quinolinyl)oxy]-,1- methylhexyl ester;CGA 185072;Heptan-2-yl 2-((5-chloroquinolin-8-yl)oxy)acetate. Grades: 95%. CAS No. 99607-70-2. Molecular formula: C18H22ClNO3. Mole weight: 335.83. | |
| Cloretate | Synonyms: Clorethate. CAS No. 5634-37-7. Molecular formula: C5H4Cl6O3. Mole weight: 324.802. | |
| Cloretazine | Cloretazine, a sulfonyl hydrazine derivative, has been found to exhibit antineoplastic activity through influencing DNA repairment. Synonyms: Cloretazine; Laromustine; Onrigin; VNP40101M; VNP-40101M; VNP 40101M; NSC734246; NSC 734246; NSC-734246; 1-[2-chloroethyl(methylsulfonyl)amino]-3-methyl-1-methylsulfonylurea. Grades: 98%. CAS No. 173424-77-6. Molecular formula: C6H14ClN3O5S2. Mole weight: 307.77. | |
| Clotrimazole Impurity A | (2-Chlorophenyl)diphenylmethane is a triarylmethane with antiproliferative activity. (2-Chlorophenyl)diphenylmethane is a degradation product of the antifungal agent Clotrimazole. Synonyms: (2-Chlorophenyl)diphenylmethanol; 2-Chloro-α,α-diphenylbenzenemethanol; NSC 170882; TRAM 3; (o-Chlorophenyl)diphenylmethanol; o-Chlorophenyldiphenylmethanol; USP Chlotrimazole Related Compound A; Benzenemethanol, 2-chloro-α,α-diphenyl-; Clotrimazole EP Impurity A; MDK-4025. Grades: ≥95%. CAS No. 66774-02-5. Molecular formula: C19H15ClO. Mole weight: 294.77. | |
| Clotrimazole Impurity B | para-Clotrimazole Isomer is a positional isomer of the antifungal agent. It showed agonistic activity on the pregnane X receptor and regulated the levels of apoA1 and HDL-cholesterol in rodents. Synonyms: para-Clotrimazole Isomer; 1-[(4-Chlorophenyl)diphenylmethyl]-1H-imidazole; 1-(p-Chloro-α,α-diphenylbenzyl)imidazole; 1-[ (p-Chlorophenyl) diphenylmethyl]imidazole; CDD 3532. Grades: > 95%. CAS No. 23593-71-7. Molecular formula: C22H17ClN2. Mole weight: 344.84. | |
| Clovin | Clovin is a compound of the flavonoid class found in the herbs of Viola yedoensis. Synonyms: 4H-1-Benzopyran-4-one, 3-((6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-galactopyranosyl)oxy)-7-((6-deoxy-alpha-L-mannopyranosyl)oxy)-2-(3,4-dihydroxyphenyl)-5-hydroxy-. Grades: >98%. CAS No. 81970-00-5. Molecular formula: C33H40O20. Mole weight: 756.663. | |
| Cloxyfonac | Cloxyfonac is a plant growth regulator and a chemical transformation product. Synonyms: Cloxyfonac; 6386-63-6; Clocxyfonac; 2-(4-Chloro-2-(hydroxymethyl)phenoxy)acetic acid2-[4-chloro-2-(hydroxymethyl)phenoxy]acetic acid. Grades: >98%. CAS No. 6386-63-6. Molecular formula: C9H9ClO4. Mole weight: 216.62. | |
| Clozapine EP Impurity D | [2-[(2-Amino-4-chlorophenyl)amino]phenyl](4-methyl-1-piperazinyl)methanone is used in the synthesis of substituted dibenzodiazepines. It is also an impurity in the synthesis of Clozepine, an antipsychotic. Synonyms: [2-[(2-Amino-4-chlorophenyl)amino]phenyl](4-methyl-1-piperazinyl)methanone; 1-[2-[(2-Amino-4-chlorophenyl)amino]benzoyl]-4-methylpiperazine. Grades: > 95%. CAS No. 65514-71-8. Molecular formula: C18H21ClN4O. Mole weight: 344.84. | |
| Clozapine N-Oxide | Clozapine N-oxide is a major metabolite of clozapine, and acts as an antagonist of 5-HT receptor. Uses: Antipsychotic agents. Synonyms: 3-chloro-6-(4-methyl-4-oxidopiperazin-4-ium-1-yl)-11H-benzo[b][1,4]benzodiazepine. Grades: >98%. CAS No. 34233-69-7. Molecular formula: C18H19ClN4O. Mole weight: 342.827. | |
| CLP 257 | CLP 257 has been found to be a KCC2 K+-Cl- cotransporter activator and could alleviates hypersensitivity in rats with peripheral nerve injury. Synonyms: CLP 257; CLP-257; CLP257; (5Z)-5-[(4-Fluoro-2-hydroxyphenyl)methylene]-2-(tetrahydro-1-(2H)-pyridazinyl)-4(5H)-thiazolone. Grades: ≥98% by HPLC. CAS No. 1181081-71-9. Molecular formula: C14H14FN3O2S. Mole weight: 307.34. | |
| CLR1501 | CLR1501 is a selective fluorescent compound for cancer cells. Synonyms: 5, 5-Difluoro-10- (4- (18- ( (oxido (2- (trimethylammonio) ethoxy) phosphoryl) oxy) octadecyl) phenyl) -5H-dipyrrolo[1, 2-c: 2', 1'-f][1, 3, 2]diazaborinin-4-ium-5-uide. Grades: 98%. CAS No. 1250963-36-0. Molecular formula: C38H59BF2N3O4P. Mole weight: 701.67. | |
| CMK | CMK is a RSK2 kinase inhibitor. Its IC50 value for Cdc5(L158G) is 36 nM. It is used in the preparation of serine/threonine kinase inhibitors. Uses: Cmk is used in the preparation of serine/threonine kinase inhibitors. Synonyms: 1-(4-Amino-7-(3-hydroxypropyl)-5-(p-tolyl)-7h-pyrrolo[2,3-d]pyrimidin-6-yl)-2-chloroethanone. Grades: 95%. CAS No. 821794-90-5. Molecular formula: C18H19ClN4O2. Mole weight: 358.82. | |
| CMP5 | CMP5 is a potent and selective PRMT5 inhibitor suppressing EBV-driven B-lymphocyte transformation while leaving normal B cells unaffected. Inhibition of PRMT5 effetively blocked recall T cell responses, reduced inflammation in delayed-type hypersensitivity and clinical disease in experimental autoimmune encephalomyelitis mouse models. Synonyms: CMP5; CMP 5; CMP-5; 1-(9-ethylcarbazol-3-yl)-N-(pyridin-2-ylmethyl)methanamine Hydrochloride; AKOS032401780. Grades: 99%. CAS No. 1030021-40-9. Molecular formula: C20H22N3.HCl. Mole weight: 351.87. | |
| CMPD101 | CMPD101 is a selective GRK2/3 inhibitor with IC50 value is 54 nM for GRK3 and 32 nM for GRK2. It shows selectivity for GRK2/3 over GRK1/5. It can also reduce DAMGO-induced desensitization and internalization of μ-opioid receptors. Synonyms: CMPD101; CMPD 101; CMPD-101; Takeda101; Takeda-101; Takeda 101. 3-[[[4-Methyl-5- (4-pyridinyl) -4H-1, 2, 4-triazol-3-yl]methyl]amino]-N-[[2- (trifluoromethyl) phenyl]methyl]benzamide. Grades: 98%. CAS No. 865608-11-3. Molecular formula: C24H21F3N6O. Mole weight: 466.46. | |
| CMP-Neu5,9Ac2 | CMP-Neu5,9Ac2 serves as a direct substrate of the NeuA O-acetyl esterase in vitro. Synonyms: β-Neuraminic acid, N-acetyl-, 9-acetate 2-(hydrogen 5'-cytidylate), ammonium salt (1:2). CAS No. 1045785-97-4. Molecular formula: C22H33N4O17P.2NH3. Mole weight: 690.55. | |
| c-Myc Peptide | c-Myc Peptide Trifluoroacetate is a synthetic peptide corresponding to the C-terminal amino acids (410-419) of human c-myc protein, and participates in regulation of growth-related gene transcription. Synonyms: H-Glu-Gln-Lys-Leu-Ile-Ser-Glu-Glu-Asp-Leu-OH; L-alpha-glutamyl-L-glutaminyl-L-lysyl-L-leucyl-L-isoleucyl-L-seryl-L-alpha-glutamyl-L-alpha-glutamyl-L-alpha-aspartyl-L-leucine; L-Leucine, L-α-glutamyl-L-glutaminyl-L-lysyl-L-leucyl-L-isoleucyl-L-seryl-L-α-glutamyl-L-α-glutamyl-L-α-aspartyl-; L-Leucine, N-[N-[N-[N-[N-[N-[N-[N2-(N2-L-α-glutamyl-L-glutaminyl)-L-lysyl]-L-leucyl]-L-isoleucyl]-L-seryl]-L-α-glutamyl]-L-α-glutamyl]-L-α-aspartyl]-; L-α-Glutamyl-L-glutaminyl-L-lysyl-L-leucyl-L-isoleucyl-L-seryl-L-α-glutamyl-L-α-glutamyl-L-α-aspartyl-L-leucine; c-Myc epitope tag; c-Myc-tag; cMYC tag (synthetic); Myc peptide; Myc-tag; Neuroblastoma suppressor of tumorigenicity 1 (human clone WO2014/074532-SEQID-317); Transcription factor c-myc (fragment); Transcription factor c-myc (synthetic C-terminal epitope). Grades: ≥95%. CAS No. 145646-22-6. Molecular formula: C51H86N12O21. Mole weight: 1203.30. | |
| Cnidilin | Cnidilin is a compound of the coumarin class found in the roots of Angelica dahurica. Cnidilin has the potential for the treatment of CNS diseases for its BBB permeability. Synonyms: Kinidilin; Isophellopterin; 9-methoxy-4-(3-methylbut-2-enoxy)furo[3,2-g]chromen-7-one. Grades: >98%. CAS No. 14348-22-2. Molecular formula: C17H16O5. Mole weight: 300.31. | |
| CNQX | CNQX, also known as FG9065, is a potent and competitive AMPA/kainate receptor antagonist and also antagonist at glycine modulatory site on NMDA receptor complex. Uses: Excitatory amino acid antagonists. Synonyms: 7-nitro-2,3-dioxo-1,4-dihydroquinoxaline-6-carbonitrile; 1,4-dihydro-2,3-dihydroxy-7-nitro-6-quinoxalinecarbonitrile; 6 Cyano 2,3 dihydroxy 7 nitroquinoxaline; 6 Cyano 7 nitroquinoxaline 2,3 dione; 6-Cyano-2,3-dihydroxy-7-nitroquinoxaline; 6-Cyano-7-nitroquinoxaline-2,3-dione; CNQX; FG 9065; FG-9065; FG9065. CAS No. 115066-14-3. Molecular formula: C9H4N4O4. Mole weight: 232.15. | |
| Cobicistat | Cobicistat is a potent inhibitor of cytochrome P450 3A enzymes, including the important CYP3A4 subtype. It also inhibits intestinal transport proteins, increasing the overall absorption of several HIV medications, including atazanavir, darunavir and tenofovir alafenamide fumarate. Uses: Anti-hiv agents. Synonyms: Cobicistat, GS-9350; GS 9350; GS9350. Grades: 0.99. CAS No. 1004316-88-4. Molecular formula: C40H53N7O5S2. Mole weight: 776.028. | |
| Columbianetin | Columbianetin is isolated from Radix Angelicae Pubescentis. Columbianetin inhibited the histamine release by substance P. It may be helpful in regulating mast cell-mediated allergic inflammatory responses. Uses: Inhibition of platelet aggregation, inhibition of fungus. Synonyms: 2H-Furo(2,3-h)-1-benzopyran-2-one, 8,9-dihydro-8-(1-hydroxy-1-methylethyl)-, (S)-. Grades: >98%. CAS No. 3804-70-4. Molecular formula: C14H14O4. Mole weight: 246.26. | |
| Columbianetin acetate | Columbianetin acetate is a coumarin with anti-fungal and anti-inflammatory activity. Synonyms: (+)-Columbianetin acetate; (S)-Columbianetin acetate; O-Acetylcolumbianetin. Grades: 0.98. CAS No. 23180-65-6. Molecular formula: C16H16O5. Mole weight: 288.3. | |
| Commendamide | Commendamide is a natural bacterial product which was discovered in a screen for commensal bacteria effector genes (Cbegs). Commendamide is structurally similar to long-chain N-acyl-amides, which commonly signal, in mammals, through G protein-coupled receptors. Commendamide activates GPR132 (also known as G2A) with an EC50 value of 11.8 μM. Synonyms: N-acyl-3-hydroxypalmitoyl-Glycine; 2-(3-hydroxyhexadecanoylamino)acetic acid. Grades: ≥95%. CAS No. 193825-78-4. Molecular formula: C18H35NO4. Mole weight: 329.5. | |
| Complanatuside A | Complanatuside A, a flavonoid compound, is isolated from Astragalus complanatus and Lysimachia christinae. Astragalus complanatus R.Brown is a widely used herbal material in traditional Chinese medicine. The total flavonoid (TF) is an active fraction extracted from seeds of Astragalus complanatus R.Brown. Previous studies performed in animals have demonstrated the antihypertensive efficacy of the TF. Synonyms: Complanatuside; 3-(beta-D-Glucopyranosyloxy)-2-[4-(beta-D-glucopyranosyloxy)phenyl]-5-hydroxy-7-methoxy-4H-1-benzopyran-4-one. Grades: > 98%. CAS No. 116183-66-5. Molecular formula: C28H32O16. Mole weight: 624.54. | |
| Compound 43 TAO Kinase Inhibitor | Compound 43 TAO kinase inhibitor is an ATP-competitive and selective inhibitor of TAOK1 and TAOK2 (IC50s = 11 and 15 nM, respectively). It is selective for TAOK1 and TAOK2 over 62 kinases in a panel, but does inhibit TAOK3 by 87% and seven additional kinases by 21-52%. Synonyms: N-[2-oxo-2-[(1,2,3,4-tetrahydro-1-naphthalenyl)amino]ethyl]-[1,1'-biphenyl]-4-carboxamide. Grades: ≥98%. CAS No. 850467-66-2. Molecular formula: C25H24N2O2. Mole weight: 384.47. | |
| Conduritol B epoxide | Conduritol B epoxide (CBE) is an irreversible inhibitor of covalently bound acid β-glucosidase, also known as GBA, or GBA1 (IC50 = 9 μM). It also does not inhibit non-lysosomal glucosylceramidase or cytosolic β-glucosidase. Synonyms: CBE; 1,2-anhydro-myo-inositol. Grades: ≥95%. CAS No. 6090-95-5. Molecular formula: C6H10O5. Mole weight: 162.1. | |
| Conivaptan Hydrochloride | Conivaptan HCl is a non-peptide inhibitor of antidiuretic hormone (vasopressin receptor antagonist). Uses: Antidiuretic hormone receptor antagonists. Synonyms: N-[4-[(4,5-Dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-[1,1'-Biphenyl]-2-carboxamide Hydrochloride; Vaprisol; YM 087; [1,1'-Biphenyl]-2-carboxamide, N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-, hydrochloride (1:1); [1,1'-Biphenyl]-2-carboxamide, N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-, monohydrochloride; Conivaptan monohydrochloride. Grades: >98%. CAS No. 168626-94-6. Molecular formula: C32H26N4O2.HCl. Mole weight: 535.04. | |
| Conoidin A | Peroxiredoxins are a ubiquitous family of antioxidant enzymes that also control cytokine-induced peroxide levels and thereby mediate signal transduction in mammalian cells. Conoidin A inactivates peroxiredoxins by covalently binding to the catalytic cysteine on the enzyme. It has been shown to inhibit peroxiredoxin II (IC50 = 23 μM) in the parasite T. gondii and peroxiredoxin I in the hookworm A. ceylanicum. Synonyms: 2,3-Bis(bromomethyl)quinoxaline 1,4-dioxide. Grades: ≥98%. CAS No. 18080-67-6. Molecular formula: C10H8Br2N2O2. Mole weight: 348. | |
| Continentalic acid | Continentalic acid is found in the roots of Aralia continentalis. Synonyms: Pimaradienoic acid; Pimara-8(14),15-diene-19-oic acid. Grades: > 95%. CAS No. 19889-23-7. Molecular formula: C20H30O2. Mole weight: 302.45. | |
| Coptisine Sulfate | Coptisine Sulfate is an alkaloid isolated from Chinese goldthread. It exhibits growth inhibitory activity against human cancer cell line in the NCI's anticancer drug screening program. Uses: Anticancer. Synonyms: 6,7-Dihydro-bis[1,3]benzodioxolo[5,6-a:4',5'-g]quinolizinium sulfate; Bis[1,3]benzodioxolo[5,6-a:4',5'-g]quinolizinium, 6,7-dihydro-, sulfate (1:1). Grades: >98%. CAS No. 1198398-71-8. Molecular formula: C19H15NO8S. Mole weight: 417.4. | |
| Corey lactone THP | Corey lactone THP, being an organic compound, has proven to be an essential building block in synthesizing several drugs, distinguishedly an antitumor agent and an angiotensin-converting enzyme inhibitor. Additionally, it finds its application as a safeguarding group for alcohols during organic synthesis. Its utilization in these domains is of critical significance owing to its potential in enhancing drug efficacy. Synonyms: (3aR,4S,5R,6aS)-4-(Hydroxymethyl)-5-((tetrahydro-2H-pyran-2-yl)oxy)hexahydro-2H-cyclopenta[b]furan-2-one; 2H-Cyclopenta[b]furan-2-one, hexahydro-4-(hydroxymethyl)-5-[(tetrahydro-2H-pyran-2-yl)oxy]-, (3aR,4S,5R,6aS)-. Grades: 95%. CAS No. 69222-61-3. Molecular formula: C13H20O5. Mole weight: 256.29. | |
| Corynoxeine | Corynoxeine is a potent ERK1/2 inhibitor of key PDGF-BB-induced VSMC proliferation and a useful and prospective compound in the prevention and treatment for vascular diseases. Uses: Antihypertension. Synonyms: corynoxeine; (7R,16E,20α)-16,17,18,19-Tetradehydro-17-methoxy-2-oxocorynoxan-16-carboxylic acid methyl ester; (alphaE,1'R,6'R,7'S,8'aS)-6'-Ethenyl-1,2,2',3',6',7',8',8'a-octahydro-alpha-(methoxymethylene)-2-oxospiro[3H-indole-3,1'(5'H)-indolizine]-7'-acetic acid methyl ester; 16,17,18,19-Tetradehydro-17-methoxy-2-oxocorynoxan-16-carboxylic acid methyl ester; Spiro[3H-indole-3,1'(5'H)-indolizine]-7'-aceticacid, 6'-ethenyl-1,2,2',3',6',7',8',8'a-octahydro-a-(methoxymethylene)-2-oxo-, methyl ester, (aE,1'R,6'R,7'S,8'aS)-. Grades: >98%. CAS No. 630-94-4. Molecular formula: C22H26N2O4. Mole weight: 382.45. | |
| Corynoxine B | Corynoxine B, a natural autophagy inducer, restores the deficient cytosolic translocation of HMGB1 and autophagy in cells overexpressing SNCA, which may be attributed to its ability to block SNCA-HMGB1 interaction. Corynoxine B exhibited prolongation of the thiopental-induced hypnosis on oral administration in mice. Synonyms: Corynoxine B. Grades: >98%. CAS No. 17391-18-3. Molecular formula: C22H28N2O4. Mole weight: 384.47. | |
| (±)-Corypalmine | Corypalmine is an alkaloid used as an antifungal. Synonyms: 6H-Dibenzo[a,g]quinolizin-3-ol, 5,8,13,13a-tetrahydro-2,9,10-trimethoxy-; 5,8,13,13a-Tetrahydro-2,9,10-trimethoxy-6H-dibenzo[a,g]quinolizin-3-ol; Berbin-3-ol, 2,9,10-trimethoxy-, (±)-; (R,S)-Tetrahydrojatrorrhizine; (±)-Corypalmine; (±)-Discretinine; (±)-Tetrahydrojatrorrhizine; 2,9,10-Trimethoxyberbin-3-ol; DL-Tetrahydrojatrorrhizine; dl-Corypalmine; dl-Tetrahydrojatrorrhizine; Jatrorrhizine, tetrahydro-; Tetrahydrojatrorrhizine; Corypalmine. Grades: ≥95%. CAS No. 27313-86-6. Molecular formula: C20H23NO4. Mole weight: 341.40. | |
| (+)-CORYPALMINE | Cas No. 6018-40-2. | |
| COTI 219 | COTI 219 is an oral small-molecule inhibitor of the KRAS mutant form, without affecting normal KRAS function. Synonyms: COTI-219; 4-Methyl-1-piperazinecarbothioic Acid 2-(9H-Cyclopenta[1,2-b:4,3-b']dipyridin-9-ylidene)hydrazide. CAS No. 1039455-85-0. Molecular formula: C17H18N6S. Mole weight: 338.43. | |
| Cot inhibitor-1 | Cot inhibitor-1 is a COT/Tpl2 inhibitor. Synonyms: 3-Quinolinecarbonitrile, 8-chloro-4-[(3-chloro-4-fluorophenyl)amino]-6-[[[1-[2-(hexahydro-1H-azepin-1-yl)ethyl]-1H-1,2,3-triazol-4-yl]methyl]amino]-. Grades: >98%. CAS No. 915365-57-0. Molecular formula: C27H27Cl2FN8. Mole weight: 553.46. | |
| Cot inhibitor-2 | Cot inhibitor-2 is a COT/Tpl2 inhibitor. Synonyms: 3-Quinolinecarbonitrile, 8-chloro-4-[(3-chloro-4-fluorophenyl)amino]-6-[[[1-(1-ethyl-4-piperidinyl)-1H-1,2,3-triazol-4-yl]methyl]amino]-. Grades: >98%. CAS No. 915363-56-3. Molecular formula: C26H25Cl2FN8. Mole weight: 539.43. | |
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