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Celgosivir hydrochloride
Celgosivir hydrochloride is the hydrochloride salt of Celgosivir which is anα-glucosidase inhibitor and inhibits bovine viral diarrhoea virus (BVDV) with an IC50 of 1.27 μM in vitro assay. Synonyms: [(1S,6S,7S,8R,8aR)-1,7,8-trihydroxy-1,2,3,5,6,7,8,8a-octahydroindolizin-6-yl] butanoate;hydrochloride; Celgosivir HCl; UNII-70U2NQU0FP; Celgosivir (hydrochloride); MDL 28574A. Grades: ≥98% (HPLC). CAS No. 141117-12-6. Molecular formula: C12H22ClNO5. Mole weight: 295.76.
Celiprolol Impurity B
N,N'-Bis[3-acetyl-4-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]phenyl]-urea is an impurity of Celiprolol which is a cardioselective β1-adrenergic blocker. Synonyms: N 113; Celiprolol Aniline Carboxy Dimer. Grades: > 95%. CAS No. 125579-40-0. Molecular formula: C31H46N4O7. Mole weight: 586.73.
Cellulose sulfate sodium salt
Cellulose sulfate sodium salt is a critically significant compound within the realm of biomedical sciences, standing as an avant-garde solution catering to the research of paramount viral afflictions such as HIV/AIDS and various sexually transmitted diseases. Synonyms: Sodium cellulose sulfate; Kelco SCS. Grades: >98%. CAS No. 9005-22-5.
Cenerimod
Cenerimod is an active Lysosphingolipid receptor agonist originated by Actelion Pharmaceuticals and EC50 value is 2.7 nM. It is a S1P1/EDG1 receptor agonist and has a long-lasting immunomodulating effect through reducing the number of circulating and infiltrating T- and B-lymphocytes, without affecting their maturation, memory, or expansion. Cenerimod is in phase I/II clinical trials for the treatment of Systemic lupus erythematosus. Uses: Systemic lupus erythematosus. Synonyms: ACT-334441; ACT334441; ACT 334441; (S)-3-(4-(5-(2-cyclopentyl-6-methoxypyridin-4-yl)-1,2,4-oxadiazol-3-yl)-2-ethyl-6-methylphenoxy)propane-1,2-diol. Grades: 98%. CAS No. 1262414-04-9. Molecular formula: C25H31N3O5. Mole weight: 453.54.
Cenicriviroc
Cenicriviroc is an inhibitor of CCR2 and CCR5 receptors, allowing it to function as an entry inhibitor which prevents the virus from entering into a human cell as an experimental drug candidate for the treatment of HIV infection. Uses: Ccr2 receptor antagonists; ccr5 receptor antagonists. Synonyms: (S,E)-8-(4-(2-Butoxyethoxy)phenyl)-1-isobutyl-N-(4-(((1-propyl-1H-imidazol-5-yl)methyl)sulfinyl)phenyl)-1,2,3,4-tetrahydrobenzo[b]azocine-5-carboxamide; TAK-652; TAK652; TAK 652; TBR-652; TBR 652; TBR652; Cenicriviroc. Grades: ≥98%. CAS No. 497223-25-3. Molecular formula: C41H52N4O4S. Mole weight: 696.95.
Cenicriviroc mesylate
Cenicriviroc is an inhibitor of CCR2 and CCR5 receptors, allowing it to function as an entry inhibitor which prevents the virus from entering into a human cell as an experimental drug candidate for the treatment of HIV infection. Synonyms: TAK-652 mesylate; TAK 652 mesylate; TBR-652 mesylate; TBR 652 mesylate. Grades: 99.04%. CAS No. 497223-28-6. Molecular formula: C42H56N4O7S2. Mole weight: 793.051.
Centhaquine
Centhaquin is a new type of drug with the potential to treat hemorrhagic shock. Synonyms: Centhaquin; Compound-7173; PMZ-2010; PMZ-2010. Grades: 98%. CAS No. 57961-90-7. Molecular formula: C22H25N3. Mole weight: 331.5.
Cephalomannine
Cas No. 71610-00-9.
Ceralifimod
Ceralifimod (ONO-4641) is a selective agonist of sphingosine 1-phosphate (S1P) receptor 1 and 5 (EC50 = 0.0273 and 0.334?nM). In animal experiment, ONO-4641 prevented relapse of disease in a non-obese diabetic mouse model of relapsing-remitting EAE. ONO-4641 had been developed for the treatment of multiple sclerosis (MS) and undergone a phase II clinical trial by Merck KGaA and Ono, therefore, the study were terminated in Dec 2014. Uses: Ceralifimod (ono-4641) is a selective agonist of sphingosine 1-phosphate (s1p) receptor 1 and 5 (ec50 = 0.0273 and 0.334?nm) developed for the treatment of multiple sclerosis (ms). Synonyms: ONO-4641; ONO 4641; ONO4641; Ceralifimod. UNII-BZ2O8A84A4; 891859-12-4; AK173892; Ceralifimod [INN]; SCHEMBL465051; 1-[[6-[(2-methoxy-4-propylphenyl)methoxy]-1-methyl-3,4-dihydronaphthalen-2-yl]methyl]azetidine-3-carboxylic acid. Grades: ≥98%. CAS No. 891859-12-4. Molecular formula: C27H33NO4. Mole weight: 435.564.
Ceranib 1
Ceranib 1 is a ceramidase inhibitor. It inhibits proliferation in SKOV3 ovarian carcinoma cells. It decreases sphingosine and sphingosine-1-phosphate (S1P) levels in SKOV3 cells and induces accumulation of ceramide species. It is a useful research chemical and has an antiproliferative effect. Synonyms: 3-[(2E)-3-(4-Methoxyphenyl)-1-oxo-2-propen-1-yl]-6-methyl-4-phenyl-2(1H)-quinolinone; 6-Methyl-3-[3-(4-methoxyphenyl)-1-oxo-2-propenyl]-4-phenyl-2(1H)-quinolinone. Grades: ≥98% by HPLC. CAS No. 328076-61-5. Molecular formula: C26H21NO3. Mole weight: 395.45.
Ceranib-2
Ceranib-2 is an inhibitor of cellular ceramidase activity, which can inhibit ceramidase activity with IC50 of 28 μM in SKOV3 cells. It can catalyze the hydrolysis of the N-acyl linkage between the fatty acid and sphingosine base in ceramide to produce sphingosine and a free fatty acid. Ceranib-2 decreases levels of sphingosine and sphingosine-1-phosphate (S1P), and inhibits cell proliferation. Grades: ≥98%. CAS No. 1402830-75-4. Molecular formula: C25H19NO3. Mole weight: 381.4.
Cerdulatinib HCl
Cerdulatinib is a dual SYK/JAK inhibitor. It significantly reduces cell viability in a subset of NHL cell lines, and induces apoptosis in BCR-signaling competent NHL cell lines. Synonyms: Cerdulatinib hydrochloride; PRT2070 hydrochloride; 4-(cyclopropylamino)-2-[4-(4-ethylsulfonylpiperazin-1-yl)anilino]pyrimidine-5-carboxamide hydrochloride. Grades: >98%. CAS No. 1369761-01-2. Molecular formula: C20H28ClN7O3S. Mole weight: 482.
Ceritinib
An anaplastic lymphoma kinase (ALK)-positive inhibitor used for the treatment of non-small cell lung cancer (NSCLC). It less potently inhibits IGF-1R, InsR, and STK22D and IC50 value is 8, 7, and 23 nM. LDK378 is also minimally effective against a panel of other kinases. In Sep 2016, Interim adverse events and efficacy data from phase III ASCEND-4 trial in non small cell lung cancer released by Novartis. In Oct 2016, efficacy data from the phase III ASCEND-3 and ASCEND-5 trial in non small cell lung cancer was presented. Uses: Antineoplastic agents. Synonyms: 5-Chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine, LDK-378, LDK378; LDK 378; Zykadia; NVP-LDK378-NX. Grades: ≥98%. CAS No. 1032900-25-6. Molecular formula: C28H36ClN5O3S. Mole weight: 558.14.
Ceruletide
Caerulein, a CCK agonist, could be used in paralytic ileus and diagnostic aid in pancreatic malfunction. Synonyms: Caerulein; Ceruletida. Grades: ≥95% by HPLC. CAS No. 17650-98-5. Molecular formula: C58H73N13O21S2. Mole weight: 1352.40.
Cetirizine EP Impurity B Dihydrochloride
Cetirizine EP Impurity B Dihydrochloride is an impurity of Cetirizine, a second-generation antihistamine used to treat allergic rhinitis, dermatitis, and urticaria. Synonyms: 4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineacetic Acid Dihydrochloride; De(carboxymethoxy)Cetirizine Acetic Acid Dihydrochloride; Levocetirizine Impurity 3 DiHCl. Grades: 98%. CAS No. 1000690-91-4. Molecular formula: C19H23Cl3N2O2. Mole weight: 417.76.
Cetirizine Glycerol Ester Impurity
An impurity of cetirizine, an antihistamine used to relieve allergy symptoms. Synonyms: Cetirizine Glycerol Ester; Acetic acid, 2-[2-[4-[(4-chlorophenyl)?phenylmethyl]?-1-piperazinyl]?ethoxy]?-, 2,?3-dihydroxypropyl ester. Grades: > 95%. CAS No. 1243652-36-9. Molecular formula: C24H31ClN2O5. Mole weight: 462.98.
Cetirizine Impurity D
Cas No. 346451-15-8.
Cetirizine methyl ester dihydrochloride
Cetirizine methyl ester dihydrochloride is a derivative of cetirizine, an antihistamine drug for the relief of symptoms of allergy and cold like sneezing and itching. Synonyms: Methyl 2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]acetate dihydrochloride. CAS No. 83881-48-5. Molecular formula: C22H29Cl3N2O3. Mole weight: 475.8.
Cetrorelix
Cetrorelix is a gonadotropin-releasing hormone antagonist that can be used in the treatment of prostate and breast cancers. Uses: Fertility agents. Synonyms: Ac-D-2-Nal-4-chloro-D-Phe-β-(3-pyridyl)-D-Ala-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2; N-acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-D-citrullyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide; D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-; SB-075. Grades: >98%. CAS No. 120287-85-6. Molecular formula: C70H92ClN17O14. Mole weight: 1431.04.
Cetrorelix diacetate
Cetrorelix is a gonadotropin-releasing hormone (GnRH) antagonist. Under the trade name Cetrotide, It is indicated for the inhibition of premature LH surges in women undergoing controlled ovarian stimulation. Synonyms: D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-, diacetate (salt); Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2.CH3CO2H; N-acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-D-citrullyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide diacetate salt. Grades: ≥95%. CAS No. 130143-01-0. Molecular formula: C74H100ClN17O18. Mole weight: 1551.16.
CFI-400936
CFI-400936 is a selective proteine kinase TTK inhibitor with IC50 value of 3.6nM. It demonstrates good activity in cell based assay and selectivity against a panel of human kinases. CFI-400936 shows potential anticancer activity. Uses: Anticancer. Synonyms: CFI400936; CFI 400936; CFI-400936. 2-(dimethylamino)-2-(2-ethylphenyl)-N-(3-(3-sulfamoylphenyl)-1H-indazol-5-yl)acetamide. Grades: 98%. CAS No. 1338793-07-9. Molecular formula: C25H27N5O3S. Mole weight: 477.58.
CFI-401980
CFI-401980, a pyrazolotriazin derivative, has been found to be a TTK inhibitor that could exhibit good antiproliferative activity in some human cancer cell lines. Ki = 0.8 nM. Synonyms: CFI-401980; CFI 401980; CFI401980; N-cyclopropyl-2-methyl-4-(2-phenoxy-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)pyrazolo[1,5-a][1,3,5]triazin-8-yl)benzamide. Grades: 98%. CAS No. 1610676-27-1. Molecular formula: C28H30N6O3. Mole weight: 498.59.
CFLZ-567
CFLZ-567 is a key intermediate for making carfilzomib. carfilzomib is a selective proteasome inhibitor as an anti-cancer drug. Uses: Key intermediate for making carfilzomib. Synonyms: carfilzomib intermediate molecule weight 567; LPhenylalanine (S) 2 (4morpholinyl) acetylaminobenzenebutanoylLleucyl; LPhenylalanine (S) (4morpholinylacetyl) aminobenzenebutanoylLleucyl (9CI);(S)-2-((S)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamido)-3-phenylpropanoic acid. Grades: 98%. CAS No. 868540-16-3. Molecular formula: C31H42N4O6. Mole weight: 566.69.
Cgp 13143
Cgp 13143 is a bio-active chemical,but no detailed information has been published yet. Synonyms: Cgp 13143; Cgp13143; Cgp-13143. ((4-methyl-2-oxo-2H-1-benzopyran-6-yl)amino)oxo-Acetic acid. Grades: 98%. CAS No. 75919-69-6. Molecular formula: C12H9NO5. Mole weight: 247.21.
Cgp 13231
Cgp 13231 is the N-oxide metabolite of amocarzine. Synonyms: Cgp 13231; Cgp13231; Cgp-13231. 1-Piperazinecarbothioamide, 4-methyl-N-(4-((4-nitrophenyl)amino)phenyl)-4-oxide. Grades: 98%. CAS No. 113962-61-1. Molecular formula: C18H21N5O3S. Mole weight: 387.46.
Cgp 15425
Cgp 15425 is a bio-active chemical,but no detailed information has been published yet. Synonyms: Cgp 15425; Cgp15425; Cgp-15425. (S)-N1-((2S,5S,8R,11S,14S,17S)-8-((1H-indol-3-yl)methyl)-11-(4-aminobutyl)-5,17-dibenzyl-14-((R)-1-hydroxyethyl)-19-imino-3,6,9,12,15,18,22-heptaoxo-1-phenyl-4,7,10,13,16-pentaazadocosan-2-yl)-2-aminosuccinamide. Grades: 98%. CAS No. 76080-70-1. Molecular formula: C56H69N11O10. Mole weight: 1056.21.
CGP-15720 hydrochloride
CGP-15720 is a antitumor agent. Uses: Antitumor. Synonyms: CGP-15720 hydrochloride; CGP-15720 HCl; CGP-15720A; CGP15720A; UNII-73G6V7978M. 4-(3-(2-(2-(pyridin-4-yl)-4,5-dihydro-1H-imidazol-1-yl)ethyl)ureido)benzoic acid hydrochloride. Grades: 98%. CAS No. 76692-12-1. Molecular formula: C18H20ClN5O3. Mole weight: 389.84.
Cgp-17520
Cgp-17520 is a new bio-active cephalosporin anti-biotic chemical comound synthesized by Ciba Geigy Ltd. Synonyms: Cgp 17520; Cgp-17520; Cgp17520. 7-(2-(4-(((2-Amino-2-carboxyethoxy)carbonyl)amino)phenyl)-2-hydroxyacetamido)-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt. Grades: >98 %. CAS No. 101706-66-5. Molecular formula: C22H24N8NaO9S2. Mole weight: 631.59.
CGP-1758 monomethanesulfonate
CGP-1758 monomethanesulfonate is a new bio-active cephalosporin anti-biotic chemical comound synthesized by Ciba Geigy Ltd. Synonyms: CGP 1758B; CGP-1758B; CGP1758B. 2-Hydroxy-5- [2- [ [2-hydroxy-3- [4- (2-methoxyethoxy) phenoxy] propyl] amino] ethoxy] benzamide monomethanesulfonate;CGP1758 monomethanesulfonate. Grades: >98%. CAS No. 108289-44-7. Molecular formula: C22H32N2O10S. Mole weight: 516.56.
Cgp 20309
Cgp 20309 has a thiocarbonylamides structure and it is a potent antifilarial agent under laboratory research stage. Uses: Antifilarial agent. Synonyms: Cgp 20309; Cgp20309; Cgp-20309. N-(2-(1,1-dimethylethyl)-5-methoxy-6-benzothiazolyl)-4-methyl-1-Piperazinecarbothioamide. Grades: 98%. CAS No. 122378-48-7. Molecular formula: C18H26N4OS2. Mole weight: 378.56.
CGP 20376
CGP 20376 is a benzothiazole compound and it has antifilarial properties. Uses: Antifilarial agent. Synonyms: CGP 20376; CGP20376; CGP-20376. 3- ( ( ( (2- (1, 1-dimethylethyl) -5-methoxy-6-benzothiazolyl) amino) thioxomethyl) thio) -Propanoic acid;N-(2-tert-Butyl-5-methoxybenzothiazol-6-yl)dithiocarbonic acid 5-(1-carboxyethyl)ether. Grades: 98%. CAS No. 81059-04-3. Molecular formula: C16H20N2O3S3. Mole weight: 384.54.
Cgp 21833
Cgp 21833 has a thiocarbonylamides structure and it is a potent antifilarial agent under laboratory research stage. Uses: Antifilarial agent. Synonyms: Cgp 21833; Cgp-21833; Cgp21833. 1-(2-(1,1-dimethylethyl)-5-methyl-6-benzothiazolyl)-2-methylhydrazide 1-Piperazinecarbothioic acid. Grades: 98%. CAS No. 122378-49-8. Molecular formula: C18H27N5S2. Mole weight: 377.57.
CGP 23996
CGP 23996 is a non-reducible somatostatin analog. It can be used for autoradiography. Uses: Autoradiography. Synonyms: CGP 23996; CGP23996; CGP-23996. BDBM82467; 2-Deamino-L-Abu(1)-L-Lys-L-Asp(NH2)-L-Phe-L-Phe-L-Trp-L-Lys-L-Thr-L-Tyr-L-Thr-L-Ser-L-Abu(1)-OH;(14R,20S,23R,26R,29R,32R)-2,17-bis(4-aminobutyl)-5-(2-amino-2-oxoethyl)-8,11-dibenzyl-20,26-bis[(1S)-1-hydroxyethyl]-29-(hydroxymethyl)-23-[(4-hydroxyphenyl)methyl]-14-(1H-indol-3-ylmethyl)-3,6,9,12,15,18,21,24,27,30,38-undecaoxo-1,4,7,10,13,16,19,22,25,28,31-undecazacyclooctatriacontane-32-carboxylic acid. Grades: 98%. CAS No. 86170-12-9. Molecular formula: C73H99N15O18. Mole weight: 1474.66.
Cgp 29030A
This molecular is a piperazine derivative and its Pharmacological activity probablely is inhibition on nociceptive dorsal horn neurons that processed input from high-threshold mechanosensitive receptors in the skin and deep somatic tissues.It may be used to treat painful disorders which are complicated by increased motor. activity. Uses: Treat painful disorders. Synonyms: Cgp 29030A; Cgp29030A; Cgp-29030A. 1-p-chlorophenethyl-4-(3,5-dimethoxybenzoyl)piperazine hydrochloride. Grades: 98%. CAS No. 113240-27-0. Molecular formula: C21H26Cl2N2O3. Mole weight: 425.35.
CGP 3466B maleate
CGP 3466B maleate, a potent anti-apoptotic drug, is an orally active glyceraldehyde-3-phosphate dehydrogenase (GAPDH) inhibitor. CGP 3466B maleate was tested in clinical trials for its ability to help treat Parkinson's disease (PD) and amyotrophic lateral sclerosis (ALS) but the clinical trials have been terminated due to lack of benefit. Synonyms: N-(benzo[b][1]benzoxepin-5-ylmethyl)-N-methylprop-2-yn-1-amine;but-2-enedioic acid; Omigapil maleate; CGP 3466B; CGP-3466B; CGP3466B; TCH-346; TCH 346; TCH346; Omigapil maleate. Grades: >99 %. CAS No. 200189-97-5. Molecular formula: C23H21NO5. Mole weight: 391.42.
CGP 37157
CGP 37157 is a a selective sodium-calcium exchanger inhibitor with IC50 value of 0.36 μM in isolated mitochondria. It does not affect channels, exchangers, or ATPases on the cardiac sarcolemma or ATPases on sarcoplasmic reticulum. CGP 37157 can be used to study the role of mitochondrial-derived calcium in cytoplasmic calcium homeostasis. Synonyms: Cgp 37157; Cgp-37157; Cgp37157. 7-Chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2(3H)-one. Grades: 98%. CAS No. 75450-34-9. Molecular formula: C15H11Cl2NOS. Mole weight: 289.78.
Cgp 38560
Cgp 38560 is a potent renin inhibitor and it can induce a dose-dependent decrease in angiotensin II and plasma renin activity and a long-lasting and dose-dependent rise in active renin. Although reduction of plasma renin activity to unmeasurable levels, the doses used did not reduce plasma angiotensin II maximally. Synonyms: Cgp 38560; Cgp38560; Cgp-38560. (R)-N-(2-(((1,1-dimethylethyl)sulfonyl)methyl)-1-oxo-3-phenylpropyl)-L-histidyl-3-cyclohexyl-L-alanyl-N-butyl-L-Valinamide monomethanesulfonate. Grades: 98%. CAS No. 122088-76-0. Molecular formula: C39H64N6O9S2. Mole weight: 825.09.
CGP-42454A
CGP-42454A is a epimer of Benazepril ,an approved drug using for the treatment of Hypertension. Synonyms: CGP-42454A; CGP 42454A; CGP42454A; UNII-15B0UK1949;2-((R)-3-(((S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)acetic acid. Grades: 98%. CAS No. 131064-74-9. Molecular formula: C24H28N2O5. Mole weight: 424.49.
CGP 43182
CGP 43182, a dioxaspiro compound, has been found to a IIA sPLA2 inhibitor that could have potential anti-inflammatory effect and also in influencing the synergistic effect brought by pro-inflammatory genes. Synonyms: Cgp 43182; Cgp-43182; Cgp43182. N-(2,3-Dichlorophenyl)-2-hydroxy-4-oxo-1,5-dioxaspiro(5.5)undec-2-ene-3-carboxamide; N-(2,3-dichlorophenyl)-2-hydroxy-4-oxo-1,5-dioxaspiro[5.5]undec-2-ene-3-carboxamide; AC1L2SHN; DTXSID00164535. Grades: 98%. CAS No. 150379-37-6. Molecular formula: C16H15Cl2NO5. Mole weight: 372.20.
Cgp 43902A
Cgp 43902A is a bio-active molecular, but no detailed information has been published yet. Synonyms: Cgp 43902A; Cgp43902A; Cgp-43902A. ethyl 2-[(4Z)-5-(hydroxymethyl)-2-methyl-3-oxo-4-[(2-pyridin-2-ylhydrazinyl)methylidene]pyridin-1-ium-1-yl]acetate;bromide. Grades: 98%. CAS No. 124076-31-9. Molecular formula: C17H21BrN4O4. Mole weight: 425.28.
CGP 47072
CGP 47072, a bisphosphonate derivative, has been found to be a calcium regulator and was once studied in the treatment of osteoporosis. Synonyms: Cgp 47072; Cgp47072; Cgp-47072.CHEMBL101886; AC1L4IPT; SCHEMBL7164644; [1-hydroxy-3-[methyl(3-phenoxypropyl)amino]-1-phosphonopropyl]phosphonic acid. Grades: 98%. CAS No. 158859-42-8. Molecular formula: C13H23NO8P2. Mole weight: 383.27.
CGP 57380
CGP 57380 is a potent MNK1 inhibitor with IC50 of 2.2 μM, exhibiting no inhibitory activity on p38, JNK1, ERK1 and -2, PKC, or c-Src-like kinases. Synonyms: CGP-57380; CGP57380; CGP 57380. Grades: >98%. CAS No. 522629-08-9. Molecular formula: C11H9FN6. Mole weight: 244.23.
CGP-62198A
CGP-62198A, a piperidine derivative, could probably be useful in some biological studies. Synonyms: CGP-62198A; CGP 62198A; CGP62198A; UNII-WXF63HI1WD; WXF63HI1WD; SCHEMBL6042796. Benzamide, N-((2S,4S,5S,7S)-7-(((2-(4-acetyl-1-piperidinyl)ethyl)amino)carbonyl)-4-amino-5-hydroxy-8-methyl-2-(1-methylethyl)nonyl)-2-(4-methoxybutoxy)-. Grades: 98%. CAS No. 180183-51-1. Molecular formula: C35H60N4O6. Mole weight: 632.89.
CGP 71683 hydrochloride
CGP 71683 hydrochloride is a highly selective non-peptide antagonist of the NPY Y(5) receptor (IC50= 1.4 nM) with > 1000-fold selectivity over Y1 (IC50= 2765 nM), Y2 (IC50= 7187 nM) and Y4 (IC50= 5637 nM) receptors. Potently inhibits NPY-induced food intake following i.p. administration in diabetic, free-feeding and fasted rats. Synonyms: N- [ [4- [ [ (4-aminoquinazolin-2-yl) amino] methyl] cyclohexyl] methyl] naphthalene-1-sulfonamide; hydrochloride; CGP 71683 A; CGP-71683A; CGP 71683 hydrochloride; CGP71683 hydrochloride; CGP-71683 hydrochloride. Grades: >99 %. CAS No. 192322-50-2. Molecular formula: C26H29N5O2S.HCl. Mole weight: 512.07.
CGP-75254A
CGP-75254A, a novel oral iron chelator, across Caco-2 cells in an attempt to model intestinal epithelial cell permeability in man. Studies predicted that absorption of CGP-75254A is likely to be virtually complete at pH values between 5.5 and 7.0. However, at pH 8.0 permeability is predicted as negligible. Synonyms: sodium;2-[2-[(2-ethoxy-2-oxoethyl)-[(2-hydroxyphenyl)methyl]amino]ethyl-[(2-hydroxyphenyl)methyl]amino]acetate; CGP-75254A; CGP 75254A; CGP75254A; UNII-94KC20I6YX; 199485-27-3 (CGP-75254A Free Acid). Grades: >98%. CAS No. 199485-26-2. Molecular formula: C22H27N2NaO6. Mole weight: 438.45.
CGP-75355
CGP-75355 is an HIV Protease inhibitor (EC50= 0.7 nM). Uses: Hiv protease inhibitors. Synonyms: CGP-75355; CGP 75355; CGP75355; UNII-4ZE7DBE752; methyl N-[(2S)-1-[2-[(2S,3S)-2-hydroxy-3-[[(2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoyl]amino]-4-phenylbutyl]-2-[(4-phenylphenyl)methyl]hydrazinyl]-3,3-dimethyl-1-oxobutan-2-yl]carbamate; 232632, BMS; 3,12-bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-((4-(2-pyridinyl)phenyl)methyl)-2,5,6,10,13-pentaazatetradecanedioic acid dimethyl ester; atazanavir; atazanavir sulfate; BMS 232632; BMS 232632 05; BMS-232632; BMS-232632-05; BMS232632; BMS23263205. Grades: >98%. CAS No. 191594-64-6. Molecular formula: C39H53N5O7. Mole weight: 703.87.
CGP 76030
CGP76030 is a ual-specific Src and Abl kinase inhibitor, inhibit growth and survival of cells expressing imatinib mesylate-resistant Bcr-Abl kinases. Uses: Ual-specific src and abl kinase inhibitor. Synonyms: CGP-76030; CGP76030; CGP76030; CGP-076030. 7-(4-(2-((2-methoxyethyl)amino)ethoxy)phenyl)-5-(3-methoxyphenyl)-7H-Pyrrolo(2,3-d)pyrimidin-4-amine. Grades: ≥98%. CAS No. 497152-38-2. Molecular formula: C24H27N5O3. Mole weight: 433.5.
Cgp 8716
Cgp 8716 is a major metabolite of GP53,633 which is a basic non-steroidal anti-inflammatory agent Originated by Novartis. Synonyms: Cgp 8716; Cgp8716; Cgp-8716. 4-(2-(1,1-dimethylethyl)-5-(3-pyridinyl)-1H-imidazol-4-yl)-Phenol. Grades: 98%. CAS No. 84782-21-8. Molecular formula: C18H19N3O. Mole weight: 293.36.
CH 141
CH 141 is a peripheral vasodilator. Uses: Peripheral vasodilator. Synonyms: 6-((3,4-dihydroisoquinolin-2(1H)-yl)methyl)-3-phenyl-5,6-dihydro-2H-1,2,4-oxadiazine; CH 141; CH-141; CH141; Pthiqdo. Grades: 98%. CAS No. 78279-88-6. Molecular formula: C19-H21-N3-O. Mole weight: 307.39.
CH 150
CH 150 is a bio-active chemical, but detailed information has not been published. Synonyms: CH 150; CH150; CH-150. 3-Ethyl-2,6-dimethyl-4H-pyrido(1,2-a)pyrimidin-4-one. Grades: 98%. CAS No. 70381-44-1. Molecular formula: C12H14N2O. Mole weight: 202.26.
Chamigrenal, a pharmacological treatment of anxiety disorders, intricately works towards ameliorating the perturbed functioning of the GABA receptors that ensue due to the hyperactivity of the brain. The convoluted mechanism of action mediates a stupor gently and minimizes the manifestation of anxiety symptoms. Additionally, it occasionally serves as an adjuvant in the management of insomnia. Synonyms: Spiro[5.5]?undec-2-ene-3-carboxaldehyde, 7,?7-dimethyl-11-methylene-, (-)?-. Grades: >98%. CAS No. 19912-84-6. Molecular formula: C15 H22 O. Mole weight: 218.33.
Cheilanthifoline
Cheilanthifoline is an alkaloid isolated from rhizomes of Sinomenium acutum with anti-osteoclastogenic property. Synonyms: (S)-Cheilanthifoline; (6aS)-6,6a,11,14-Tetrahydro-8-methoxy-12H-benzo[a]-1,3-benzodioxolo[4,5-g]quinolizim-9-ol; (6aS)-9-methoxy-6,11,12,14-tetrahydro-2H,6aH-[1,3]dioxolo[4,5-h]isoquino[2,1-b]isoquinolin-8-ol. Grades: >98%. CAS No. 483-44-3. Molecular formula: C19H19NO4. Mole weight: 325.264.
CHEMBL2426474
CHEMBL2426474, also called as UNC1079, the piperidine analog of UNC1021 that has binding affinity to L3MBTL3 in human G401 cells by Western blot based pulldown assay. Synonyms: CHEMBL2426474UNC1079; UNC-1079; UNC 1079.1,4-Phenylenebis(1,4'-bipiperidin-1'-ylmethanone)1418741-86-2BDBM50440571AKOS025405429CS-5532; AK-185224; HY-18373; CS 5532; AK 185224; HY 18373; CS5532; AK185224; HY183731,4-Bis(4-(piperidinyl)piperidinyl)benzamide. CAS No. 1418741-86-2. Molecular formula: C28H42N4O2. Mole weight: 466.67.
CHEMS
CHEMS is an acidic cholesterol ester. It self-assembles into bilayers in alkaline and neutral aqueous media. Synonyms: cholesteryl hemisuccinate; Cholesterol Hydrogen Succinate; 3beta-Hydroxy-5-cholestene 3-hemisuccinate. Grades: >99%. CAS No. 1510-21-0. Molecular formula: C31H50O4. Mole weight: 486.73.
CHF 1255
CHF 1255, a tetrahydronaphthalen derivative, has been found to be probably effective against heart failure. Synonyms: CHF 1255; CHF1255; CHF-1255. SCHEMBL7435679; 5,6-Dimethoxy-2-(3'-(4-hydroxyphenyl)-3'-hydroxy-2'-propyl)aminotetralin; 146728-52-1; 4-[1-Hydroxy-2-[[(5,6-dimethoxy-1,2,3,4-tetrahydronaphthalen)-2-yl]amino]propyl]phenol. Grades: 98%. CAS No. 146728-52-1. Molecular formula: C21H27NO4. Mole weight: 357.44.
CHF-5022 is a non-steroidal anti-inflammatory agent. It can selectively inhibit the production of beta-amyloid(1-42). Uses: Anti-inflammatory agent. Synonyms: CHF-5022; CHF 5022; CHF5022; UNII-JO8EVV007Q; CHEMBL196246; CHF-5022; JO8EVV007Q; SCHEMBL1373506; BDBM50172463. UNII-JO8EVV007Q; CHEMBL196246; CHF-5022; JO8EVV007Q; SCHEMBL1373506; BDBM50172463;Cyclopropanecarboxylic acid, 1-(2-fluoro-4'-(trifluoromethyl)(1,1'-biphenyl)-4-yl)-. Grades: 98%. CAS No. 749269-77-0. Molecular formula: C17H12F4O2. Mole weight: 324.27.
Chicanin
Chicanin is a lignan isolated from the fruits of Osmanthus fragrans. Studies show that chicanine exhibits anti-inflammatory activity on murine macrophage by down-regulating LPS-induced inflammatory cytokines in IκBα/MAPK/ERK signaling pathways and anti-proliferative effect on prostate cells. Synonyms: 4-[(2R,3S,4R,5R)-5-(1,3-benzodioxol-5-yl)-3,4-dimethyloxolan-2-yl]-2-methoxyphenol. Grades: >98%. CAS No. 78919-28-5. Molecular formula: C20H22O5. Mole weight: 342.391.
Chimonanthine
Chimonanthine is an alkaloid isolated from the flower buds of Chimonanthus praecox. Synonyms: 1-Demethylcalycanthidine; (-)-Chimonanthine; (3aS,8bS)-8b-[(3aS,8bS)-3-methyl-1,2,3a,4-tetrahydropyrrolo[2,3-b]indol-8b-yl]-3-methyl-1,2,3a,4-tetrahydropyrrolo[2,3-b]indole. Grades: >98%. CAS No. 5545-89-1. Molecular formula: C22H26N4. Mole weight: 346.478.
CHIR-99021
CHIR-99021 (CT99021) is a glycogen synthase kinase 3β (GSK3β) inhibitor that has antiproliferative activity in vitro and in vivo. It enhances reprogramming of mouse embryonic fibroblasts, transduced by Oct4 and Klf4 only, into iPSCs in combination with tranylcypromine. It also induces cardiomyocyte differentiation from human embryonic stem (ES). Uses: Potential antineoplastic agent. Synonyms: CHIR-99021; CT99021; 6-[2-[[4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)pyrimidin-2-yl]amino]ethylamino]pyridine-3-carbonitrile. Grades: >98%. CAS No. 252917-06-9. Molecular formula: C22H18Cl2N8. Mole weight: 465.342.
Chitinase-IN-2
Chitinase-IN-2 is a insect chitinase and N- acetyl hexosaminidase inhibitor and pesticide; 50 uM/20uM compound concentration's inhibitory percentage are 98%/92% for chitinase/N- acetyl-hexosaminidase respectively. Synonyms: Chitinase-IN-2. Grades: >98%. CAS No. 1579991-63-1. Molecular formula: C20H21N5O2S. Mole weight: 395.48.
Chlophenadione
Chlophenadione, an analogue of bromindione, could be used as an orally bioavaliable anticoagulant. Uses: Chlophenadione could be used as an orally bioavaliable anticoagulant. Synonyms: 2-(4-Chlorophenyl)-1,3-indanedione;2-(4-Chlorophenyl)indane-1,3-dione. Grades: 95%. CAS No. 1146-99-2. Molecular formula: C15H9ClO2. Mole weight: 256.68.
Chlorhexidine Dihydrochloride
Chlorhexidine hydrochloride is an antiseptic effective against a wide variety of gram-negative and gram-positive organisms. Uses: Antiseptic. Synonyms: N,N''-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide Dihydrochloride; 1,1'-Hexamethylenebis(5-(p-chlorophenyl)biguanide) dihydrochloride; 1,6-Bis(N5-[p-chlorophenyl]-N1-biguanido)hexane; Chlorhexidine DiHCl; 1- (4-chlorophenyl) -3- [N- [6- [ [N- [N- (4-chlorophenyl) carbamimidoyl] carbamimidoyl] amino] hexyl] carbamimidoyl] guanidine dihydrochloride. Grades: ≥ 95%. CAS No. 3697-42-5. Molecular formula: C22H32Cl4N10. Mole weight: 578.37.
Chlorin E6
Chlorin E6 is a naturally occurring photosensitizer that can be used as a photodynamic therapy (PDT) drug candidate. Uses: Radiation-sensitizing agents. Synonyms: CE6; CE 6; CE-6; ChlorinE6; chlorin e6; (2S-trans)-18-Carboxy-20-(carboxymethyl)-13-ethyl-2,3-dihydro-3,7,12,17-tetramethyl-8-vinyl-21H,23H-porphine-2-propionic acid. Grades: 90%. CAS No. 19660-77-6. Molecular formula: C34H36N4O6. Mole weight: 596.684.
Chlorotoxin
Chlorotoxin (Cltx) is a neurotoxin that was originally isolated from the venom of Leiurus quinquestriatus. Chlorotoxin is a specific ligand of glioma cells. Chlorotoxin binds to Cl- channels (small conductance epithelial chloride channels) in the brain and spinal cord and inhibits Cl- influx. Uses: Adcs cytotoxin. Grades: >95%. CAS No. 163515-35-3. Molecular formula: C29H37N5O9S1. Mole weight: 599.64.
Chlorphenamine Impurity C Maleate
A metabolite of Chlorpheniramine, an antihistamine that works by blocking the action of histamine. Synonyms: N-Desmethyl-Chlorpheniramine; 2-[p-Chloro-α-[2-(methylamino)ethyl]benzyl]pyridine Maleate. Grades: > 95%. CAS No. 22630-25-7. Molecular formula: C15H17ClN2.C4H4O4. Mole weight: 376.8.
Chlorphenamine Impurity D
An impurity of Chlorpheniramine which is an antihistamine and works by blocking the action of histamine. Synonyms: Chlorpheniramine Nitrile. Grades: > 95%. CAS No. 65676-21-3. Molecular formula: C17H18ClN3. Mole weight: 299.81.
Chlorpromazine EP Impurity B
Chlorpromazine EP Impurity B is an impurity of chlorpromazine, an antipsychotic used to treat psychotic disorders such as schizophrenia. Synonyms: 2-Chloro-10- [3- [ [3- (dimethylamino) propyl] methylamino] propyl] phenothiazine; Chlorpromazine Impurity B. CAS No. 19077-20-4. Molecular formula: C21H28ClN3S. Mole weight: 389.986.
Chlorpromazine Sulfoxide
A devirative of Chlorpromazine. Chlorpromazine is an antipsychotic medication. It can be used to treat psychotic disorders such as schizophrenia. Synonyms: 2-Chloro-N,N-dimethyl-10H-Phenothiazine-10-propanamine 5-Oxide; 2-Chloro-10-[3-(dimethylamino)propyl]phenothiazine 5-Oxide; NSC 17470; Opromazine. Grades: > 95%. CAS No. 969-99-3. Molecular formula: C17H19ClN2OS. Mole weight: 334.87.