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Coumarin 153
Coumarin 153, a photophysical molecule with fluorescent properties, is a commonly applied dye within biomedical research and imaging. Its versatility ranges from labeling and tracking protein-protein interactions to detecting particular cellular components. Moreover, Coumarin 153 plays a vital role in the design and development of sophisticated imaging techniques for identifying and treating cancer. Uses: Coumarin 153 is used as laser dyes. Synonyms: Cumarin153;Coumarin 540A; 2,3,6,7-tetrahydro-9-(trifluoromethyl)-1H,5H,11H-[1]benzopyrano[6,7,8-ij]quinolizin-11-one; 2,3,6,7-Tetrahydro-9-trifluoromethyl-1H,5H-quinolizino(9,1-gh)coumarin. Grades: >95.0%. CAS No. 53518-18-6. Molecular formula: C16H14F3NO2. Mole weight: 309.28.
CP 100356
CP 100356 is a high affinity P-glycoprotein inhibitor.Ki value is 58 nM for mouse Pgp1a and 94nMfor Pgp1b isoforms. It can Inhibit calcein-AM uptake in MDR1-transfected MDCKII cells with IC50 value of 0.5 μM and prazosin transport in BCRP-transfected MDCKII cells with IC50 value of 1.5 μM. Preclinical development for Cancer in USA was discontinued. Uses: Cancer. Synonyms: CP 100356; CP100356; CP-100356; 4-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-N-(2-(3,4-dimethoxyphenyl)ethyl)-6,7-dimethoxy-2-Quinazolinamine; 142715-48-8(hydrochloride). Grades: >98 %. CAS No. 142716-85-6. Molecular formula: C31H36N4O6. Mole weight: 560.64.
CP 100356 hydrochloride
The hydrochloride salt form of CP-100356, which has been found to be an inhibitor of MDR1 (P-Gp) and show inactive in inhibiting multidrug resistance-associated protein 2 (MPR2). Synonyms: CP 100356 hydrochloride; CP100356 hydrochloride; CP-100356 hydrochloride; 4-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-N-2[2-(3,4-dimethoxyphenyl)ethyl]-6,7-dimethoxy-2-quinazolinamine hydrochloride. Grades: ≥98% by HPLC. CAS No. 142715-48-8. Molecular formula: C31H36N4O6.HCl. Mole weight: 597.10.
CP-100829
CP-100829, an indole derivative, could probably be useful in some biological studies. Synonyms: CP-100829; CP100829; CP 100829; UNII-X7Y3B8B649. X7Y3B8B649; 1H-Indole-1-carboxamide, 6-chloro-3-((4-chloro-2-thienyl)carbonyl)-5-fluoro-2,3-dihydro-2-oxo-; 1H-Indole-1-carboxamide, 6-chloro-3-((4-chloro-2-thienyl)hydroxymethylene)-5-fluoro-2,3-dihydro-2-oxo-, (Z)-. Grades: 98%. CAS No. 172618-05-2. Molecular formula: C14H7Cl2FN2O3S. Mole weight: 373.18.
CP21R7
CP21R7 is a potent and selective GSK3β inhibitor. It acts as an activator of stem cells prior to the induction of differentiation of stem cells to endothelial and smooth muscle cells. Uses: Cp21r7 is a selective gsk-3β inhibitor which could probably influence luciferase activity at some extent. Synonyms: 3-(3-aminophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione. Grades: >98%. CAS No. 125314-13-8. Molecular formula: C19H15N3O2. Mole weight: 317.34.
CP-220629
CP-220629, a Pyrazolopyridin derivative, has been found to be a Type 4 cyclic nucleotide phosphodiesterase inhibitor that was once studied as an anti-inflammatory as well as antiasthmatic agent. Synonyms: UNII-BAV9N49AFE; CP-220629; CP 220629; CP220629; BAV9N49AFE; SCHEMBL84865; CHEMBL75819; 1-cyclopentyl-3-ethyl-6-(2-methylphenyl)-4,5-dihydropyrazolo[3,4-c]pyridin-7-one. Grades: 98%. CAS No. 162141-96-0. Molecular formula: C20H25N3O. Mole weight: 323.44.
CP 24,879 hydrochloride
CP 24,879 is an inhibitor of arachidonic acid biosynthesis by inhibition of Δ5/Δ6 desaturase. Synonyms: p-(Isopentyloxy)-aniline; 4-(3-methylbutoxy)-benzenamine monohydrochloride. Grades: ≥98%. CAS No. 10141-51-2. Molecular formula: C11H17NO·HCl. Mole weight: 215.8.
CP 31398 dihydrochloride
CP 31398 is a p53 stabilizer and could probably restrain the growth of small human tumor xenografts in vivo. CP 31398 is a prototype small molecule that stabilizes the active conformation of p53 and promotes p53 activity in cancer cell lines with mutant or wild-type p53. Synonyms: CP31398 dihydrochloride; CP-31398 dihydrochloride; N'-[2-[2-(4-Methoxyphenyl)ethenyl]-4-quinazolinyl]-N,N-dimethyl-1,3-propanediamine dihydrochloride; 1,3-Propanediamine, N3-[2-[2-(4-methoxyphenyl)ethenyl]-4-quinazolinyl]-N1,N1-dimethyl-, hydrochloride (1:2); PZ 0115; N1-(2-(4-methoxystyryl)quinazolin-4-yl)-N3,N3-dimethylpropane-1,3-diamine dihydrochloride. Grades: ≥99% by HPLC. CAS No. 1217195-61-3. Molecular formula: C22H26N4O.2HCl. Mole weight: 435.39.
CP 346086
CP 346086 is a potent microsomal triglyceride transfer protein (MTP, MTTP) inhibitor. It reduces LDL cholesterol and triglycerides, and can be used for the treatment of obesity. Uses: The treatment of obesity. Synonyms: CP 346086; CP346086; CP-346086; N-[1,2,3,4-Tetrahydro-2-(1H-1,2,4-triazol-5-ylmethyl)-6-isoquinolinyl]-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-carboxamide. Grades: 99%. CAS No. 186390-48-7. Molecular formula: C26H22F3N5O. Mole weight: 477.48.
CP-394531
CP-394531 is an effective Glucocorticoid receptor agonist and probably has steroid-like anti-inflammatory properties with anti-GR and anti-obesity activity in animal models. Uses: Glucocorticoid receptor antagonists. Synonyms: CP-394531; CP 394531; CP394531; UNII-227D9ED2SI. (2R,4aS,10aR)-4a-benzyl-2-(chloroethynyl)-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-2,7-diol. Grades: ≥95%. CAS No. 305822-63-3. Molecular formula: C23H23ClO2. Mole weight: 366.14.
CP 424174
CP 424174 has been found to be an inhibitor of stimulus-coupled IL-1β post-translational processing. Synonyms: CP-424174; CP 424174; CP424174; CP-424,174; CP 424,174; CP424,174; N-[[[4-Chloro-2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-3-(1-hydroxy-1-methylethyl)benzenesulfonamide. Grades: ≥98% by HPLC. CAS No. 210825-31-3. Molecular formula: C22H29ClN2O4S. Mole weight: 452.99.
CP-432
CP-432 is an EP4 prostaglandin agonist , potential useful for the treatment of glaucoma and ocular hypertension. Uses: An ep4 prostaglandin agonist. Synonyms: CP-432; CP 432; CP432; CP-734432; CP 734432; CP734432. 5-(3-((2S)-2-((3R)-3-hydroxy-4-(3-(trifluoromethyl)phenyl)butyl)-5-oxo-1-pyrrolidinyl)propyl)-2-Thiophenecarboxylic acid. Grades: ≥95%. CAS No. 431990-08-8. Molecular formula: C23H26F3NO4S. Mole weight: 469.52.
CP 46665
CP 46665 is Immunomodulator. But it is lack of therapeutic activity in rodent tumors and human non-seminomatous germ cell tumors growing in nude mice. Uses: Anti-tumor. Synonyms: CP 46665; CP46665; CP-46665; CP-46,665. 4-Aminomethyl-1-(2,3-bis(decyloxy)propyl)-4-phenylpiperidine. Grades: 98%. CAS No. 72618-10-1. Molecular formula: C35H66Cl2N2O2. Mole weight: 617.82.
CP-467688
CP-467688 is a microsomal triglyceride transfer protein inhibitor used in atherosclerosis therapy. Synonyms: methyl N-[2-[6-[[2-[4- (trifluoromethyl) phenyl]benzoyl]amino]-3, 4-dihydro-1H-isoquinolin-2-yl]ethyl]carbamate; hydrochloride; 909576-25-6 (CP-467688); CP 467688; CP467688; 208590-81-2 (CP-467688 free base). Grades: >98%. CAS No. 208590-81-2. Molecular formula: C27H27ClF3N3O3. Mole weight: 533.97.
CP-472555
CP-472555 is an effective Glucocorticoid receptor agonist and probably has steroid-like anti-inflammatory properties with anti-GR and anti-obesity activity in animal models. Uses: Glucocorticoid receptor antagonists. Synonyms: CP-472555; CP 472555; CP472555; UNII-6T0KV7024R. 2-Phenanthrenecarboxamide, 4b,5,6,7,8,8a,9,10-octahydro-7-hydroxy-4b-(phenylmethyl)-7-(1-propyn-1-yl)-N-(3-pyridinylmethyl)-, (4bS,7R,8aR)-. Grades: ≥95%. CAS No. 305821-96-9. Molecular formula: C31H32N2O2. Mole weight: 464.24.
CP-5068
CP-5068 is a synthetic bio-active chemical. Uses: A synthetic bio-active chemical. Synonyms: CP-5068; CP 5068; CP5068; UNII-0UZY88DX6N. (4S,5R,6S)-3-[6-(2-amino-2-oxoethyl)-7-methylsulfanylimidazo[5,1-b][1,3]thiazol-6-ium-2-yl]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate. Grades: ≥98%. CAS No. 352305-79-4. Molecular formula: C18H20N4O5S2. Mole weight: 436.08.
CP-5484
CP-5484 is a synthetic bio-active chemical with potent anti-MRSA activity and low acute toxicity. Uses: A synthetic bio-active chemical with potent anti-mrsa activity and low acute toxicity. Synonyms: CP-5484; CP 5484; CP5484; UNII-A53TMV6VUN. (4S,5R,6S)-3-[6-[(2R)-3-amino-2-hydroxypropyl]-7-methylsulfanylimidazo[5,1-b][1,3]thiazol-6-ium-2-yl]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid;chloride. Grades: ≥98%. CAS No. 352308-27-1. Molecular formula: C19H25ClN4O5S2. Mole weight: 489.00.
CP-608039
CP-608039 is a selective adenosine A3 receptor agonist with 1,260-fold selectivity for the human A3 versus human A1 receptor. Uses: A selective adenosine a3 receptor agonist. Synonyms: CP-608039; CP608039; CP 608039; UNII-A1LB8I4247. (2S,3S,4R,5R)-3-amino-5-[6-[[5-chloro-2-[(3-methyl-1,2-oxazol-5-yl)methoxy]phenyl]methylamino]purin-9-yl]-4-hydroxy-N-methyloxolane-2-carboxamide. Grades: ≥98%. CAS No. 331727-55-0. Molecular formula: C23H25ClN8O5. Mole weight: 528.16.
CP-60949-4
CP-60949-4, a quinazolin derivative, could be probably useful in sorts of biological studies. Synonyms: CP 60949-4; CP60949-4; CP-609494. AC1L1YFM; CP 60949-4; 6-bromo-7-chloro-3-[3-(3-hydroxypiperidin-2-yl)-2-oxopropyl]quinazolin-4-one hydrobromide; 4(3H)-Quinazolinone, 6-bromo-7-chloro-3-(3-(3-hydroxy-2-piperidinyl)-2-oxopropyl)-, monohydrobromide. Grades: 98%. CAS No. 17518-97-7. Molecular formula: C16H18Br2ClN3O3. Mole weight: 495.60.
CP-640186
CP-640186 is a potent inhibitor of mammalian ACCs and can reduce body weight and improve insulin sensitivity in test animals. It has recently been shown to be a potent inhibitor of isoforms of mammalian ACCs. Most importantly, CP-640186 can reduce body fat mass and body weight, and improve insulin sensitivity, validating ACCs as targets for antiobesity and antidiabetes drugs. Synonyms: CP-640186; CP 640186; CP640186. Grades: >98%. CAS No. 591778-68-6. Molecular formula: C30H35N3O3. Mole weight: 485.62.
CP640186 HCl
CP-640186 is an isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively; with improved metabolic stability vs CP-610431. Synonyms: CP640186; CP 640186. Grades: 0.98. CAS No. 591778-70-0. Molecular formula: C30H36ClN3O3. Mole weight: 522.09.
CP-664511
CP-664511 is a potent compound that is a alpha4beta1/vascular cell adhesion molecule-1 (VCAM-1) inhibitor which has therapeutic potential in treating allergic airway disease. Uses: Alpha4bet1/vcam-1 inhibitor. Synonyms: CP-664511; CP 664511; CP664511; UNII-W1AEF8025F. 3- ( (1S) -1- ( ( (3-methoxy-4- ( ( ( (2-methylphenyl) amino) carbonyl) amino) phenyl) acetyl) amino) -3-methylbutyl) -5-Isoxazolepropanoic acid. Grades: ≥98%. CAS No. 379692-00-9. Molecular formula: C28H34N4O6. Mole weight: 522.59.
CP-67015
CP-67015 has inhibitory effect on topoisomerase function. It is a direct-acting mutagen in mammalian cells with both gene and chromosomal level effects. Uses: Cp-67015 has inhibitory effect on topoisomerase function. Synonyms: 1-Ethyl-6,8-difluoro-1,4-dihydro-4-oxo-7-(4-pyridinyl)-3-quinolinecarboxylic acid;3-Quinolinecarboxylicacid, 1-ethyl-6,8-difluoro-1,4-dihydro-4-oxo-7-(4-pyridinyl)-;CP 67015; CP 67015; CP 67015; CCRIS 2955; CP-67,015. Grades: >98 %. CAS No. 100325-51-7. Molecular formula: C17H12F2N2O3. Mole weight: 330.29.
CP-671305
CP-671305 is a potent and selective inhibitor of PDE4. Uses: Pde4 inhibitor. Synonyms: CP-671305; CP 671305; CP671305; UNII-9LH034R9R9. (R)-2-(4-((((2-((Benzo(1,3)dioxol-5-yl)oxy)pyridin-3-yl)carbonyl)amino)methyl)-3-fluorophenoxy)propionic acid. Grades: ≥98%. CAS No. 445295-04-5. Molecular formula: C23H19FN2O7. Mole weight: 54.4.
CP-671906-01
CP-671906-01 is a neuropeptide Y1 receptor antagonists, increasing blood pressure and food intake in rat models. Uses: Npy y1r antagonist. Synonyms: CP-671906; CP 671906; CP671906; UNII-GLZ1WA47Q8; CP-671906-01.N'-[3-(2,6-dichloro-4-methoxyphenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-yl]-N-(oxan-4-yl)ethane-1,2-diamine. Grades: ≥98%. CAS No. 332178-44-6. Molecular formula: C22H27Cl2N5O2. Mole weight: 464.39.
CP-67804
CP-67804 enhances topoisomerase II-mediated DNA cleavage. It represent a novel class of topoisomerase II-targeted drugs which have potential as antineoplastic agents. Uses: Cp-67804 has the potential to be used as antineoplastic agents. Synonyms: CP 67804; CP67804; CP-67804; CCRIS 8213; CP-67,804. 3-Quinolinecarboxylicacid, 1-ethyl-6,8-difluoro-1,4-dihydro-7-(4-hydroxyphenyl)-4-oxo-;CP67804;1-Ethyl-6,8-difluoro-7-(4-hydroxyphenyl)-4-quinolone-3-carboxylic acid. Grades: >98 %. CAS No. 103978-08-1. Molecular formula: C18H13F2NO4. Mole weight: 345.30.
CP-71362 is a pentapeptide renin inhibitor. It is selective for the canine enzyme. Synonyms: CP 71362; CP71362; CP-71362. L-Phenylalanine, N-(N2-(6-cyclohexyl-5-((N-(N-((1,1-dimethylethoxy)carbonyl)-L-phenylalanyl)-L-histidyl)amino)-4-hydroxy-2-(2-methylpropyl)-1-oxohexyl)-L-lysyl)-, (2R-(2R*,4S*,5S*))-. Grades: >98%. CAS No. 112227-15-3. Molecular formula: C51H76N8O9. Mole weight: 945.20.
CP-744809
CP-744809 is a highly selective orally available small molecule inhibitor of aldose reductase. Uses: Aldose reductase inhibitor. Synonyms: CP-744809; CP744809; CP 744809; ARI-809; ARI 809; ARI809; UNII-U63F8E95J1. 6-((5-chloro-3-methyl-2-benzofuranyl)sulfonyl)-3(2H)-Pyridazinone. Grades: ≥98%. CAS No. 463976-07-0. Molecular formula: C13H9ClN2O4S. Mole weight: 324.74.
CP-74667
CP-74667 is a new fluoroquinolone compound. It has good activity against several gram-positive and gram-negative pathogens. Uses: Cp-74667 has good activity against several gram-positive and gram-negative pathogens. Synonyms: CP 74667; CP74667; CP-74667; UNII-D66A707X1B. 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-7-(8-methyl-3,8-diazabicyclo(3.2.1)oct-3-yl)-4-oxo-;1-Cyclopropyl-6-fluoro-1,4-dihydro-7-(8-methyl-3,8-diazabicyclo(3.2.1)oct-3-yl)-4-oxo-3-quinolinecarboxylic acid. Grades: >98%. CAS No. 108461-05-8. Molecular formula: C20H22FN3O3. Mole weight: 371.41.
CP74725 sodium salt
CP74725 sodium salt is a bio-active chemical compound. Synonyms: CP-74725, sodium salt; UNII-0O56W95D3P; CP-74725, Na+ salt; CP-74725 salt. CP-74725 sodium salt;Sodium 2-[(2R,4R)-7-chloro-6-fluoro-4-hydroxy-2-methyl-2,3-dihydrochromen-4-yl]acetate;(2R,4R)-7-Chloro-6-fluoro-3,4-dihydro-4-hydroxy-2-methyl-2H-1-benzopyran-4-acetic acid sodium salt. Grades: >98%. CAS No. 111477-48-6. Molecular formula: C12H11ClFNaO4. Mole weight: 296.65.
Cp-76593
This active molecular is a bio-active chemical and detailed information has not been published yet. Synonyms: Cp-76593; Cp 76593; Cp76593; UNII-8SI21E44GN. (+/-)-2(1H)-Pyrimidinone, 5-(3-(bicyclo(2.2.1)hept-2-yloxy)-4-methoxyphenyl)tetrahydro-, exo-. Grades: 98%. CAS No. 115898-30-1. Molecular formula: C18H24N2O3. Mole weight: 316.39.
CP 80633
CP 80633 is an inhibitor of phosphodiesterase type 4 and exhibit anti-inflammatory and bronchodilatory effects in vivo. Synonyms: CP 80633; CP80633; CP-80633; 5-[3-[(1S,2S,4R)-Bicyclo[2.2.1]hept-2-yloxy]-4-methoxyphenyl]tetrahydro-2(1H)-pyrimidinone. Grades: ≥99% by HPLC. CAS No. 135637-46-6. Molecular formula: C18H24N2O3. Mole weight: 316.39.
CP 81282
CP 81282 shows human renin and endothiapepsin inhibitory efficacy, but no detailed data has been published yet. Synonyms: CP 81282; CP81282; CP-81282; CP-81,282. (S)-N-(4-morpholinylcarbonyl)-L-phenylalanyl-N-(1-(cyclohexylmethyl)-3,3-difluoro-4-(methylamino)-2,4-dioxobutyl)-L-Norleucinamide. Grades: 98%. CAS No. 121584-61-0. Molecular formula: C32H47F2N5O6. Mole weight: 635.74.
CP 84364
CP 84364 is an active metabolite of CP-80794 which is a Renin inhibitor. Synonyms: CP 84364; CP84364; CP84364; CP 84,364. 4-Cyclohexyl-2-hydroxy-3- (3-methylsulfanyl-2- (2- ( (morpholine-4-carbonyl) amino) -3-phenylpropionylamino) propionylamino) butyric acid. Grades: 98%. CAS No. 114457-62-4. Molecular formula: C14H18N2O4. Mole weight: 278.31.
CP-868388
CP-868388 is a bio-active chemical, but detailed information has not been published. Synonyms: (S) -2- (3- (1- ( (4-Isopropylbenzyloxy) carbonyl) piperidin-3-yl) phenoxy) -2-methylpropanoic acid;CP-868388; CP868388; CP 868388; UNII-999KY5ZIGB; (-)-CP-868388. Grades: 98%. CAS No. 702681-67-2. Molecular formula: C26H33NO5. Mole weight: 439.55.
CP-94707
CP-94707 is a new nonnucleoside reverse transcriptase inhibitor (NNRTI). Uses: Nnrt inhibitor. Synonyms: CP-94707; CP 94707; CP94707; UNII-YGC6408B5O; 3-[[4-(2-methylimidazo[4,5-c]pyridin-1-yl)phenyl]methyl]-1,3-benzothiazol-2-one. Grades: ≥98%. CAS No. 343250-05-5. Molecular formula: C21H16N4OS. Mole weight: 372.44.
cPEPCK inhibitor
cPEPCK inhibitor is the first GTP-competitive inhibitor of human cytosolic phosphoenolpyruvate carboxykinase (PEPCK or cPEPCK). Synonyms: N-[4-[1-(2-Fluorobenzyl)-3-butyl-2,6-dixo-2,3,6,7-tetrahydro-1H-purin-8-ylmethyl]phenyl]acetamide. Grades: 98%. CAS No. 628279-07-2. Molecular formula: C25H26FN5O3. Mole weight: 463.5.
c(phg-isoDGR-(NMe)k)
c(phg-isoDGR-(NMe)k) is a selective and potent α5β1-integrin ligand with IC50 of 2.9 nM. Grades: >98%. CAS No. 1844830-65-4. Molecular formula: C27H41N9O7. Mole weight: 603.67.
(±)-CPSI 1306
(±)-CPSI 1306 has been found to be a MIF inhibitor and could also be used in the synthesis of some isoxazolines compounds. Synonyms: CPSI-1306; CPSI 1306; CPSI1306; 2-[3-(3-(2,4-Difluorophenyl)-4,5-dihydro-5-isoxazolyl]-1-(4-morpholinyl)ethanone. Grades: ≥98% by HPLC. CAS No. 1309793-47-2. Molecular formula: C15H16F2N2O3. Mole weight: 310.30.
C-Reactive Protein (CRP) (174-185)
The fragment of C-Reactive Protein, a marker in the blood increasing in response to the inflammation in the body. Synonyms: H-Ile-Tyr-Leu-Gly-Gly-Pro-Phe-Ser-Pro-Asn-Val-Leu-OH; C-Reactive Protein (174-185); C-Reactive Protein 174-185. Grades: ≥98%. CAS No. 160369-86-8. Molecular formula: C62H93N13O16. Mole weight: 1276.51.
C-Reactive Protein (CRP) (77-82)
The fragment of C-Reactive Protein, a marker in the blood increasing in response to the inflammation in the body. Synonyms: H-Val-Gly-Gly-Ser-Glu-Ile-OH. Grades: 98%. CAS No. 130349-01-8. Molecular formula: C23H40N6O10. Mole weight: 560.6.
CREDAZINE is a kind of Pesticide as a herbicide. Uses: Herbicide. Synonyms: Credazine; Kusakira; NIA-20439; SW-670; SW-6721; H-722; BRN-0880257; NIA 20439; SW 670; SW 6721; H 722; BRN 0880257; NIA20439; SW670; SW6721; H722; BRN0880257; Pyridazine, 3-(2-methylphenoxy)-; 3-(2-Methylphenoxy)pyridazine. Grades: 98%. CAS No. 14491-59-9. Molecular formula: C11H10N2O. Mole weight: 186.21.
c(RGDfK)
Cyclo (-RGDfK) is a potent and selective αvβ3 integrin inhibitor. Grades: 98%. CAS No. 161552-03-0. Molecular formula: C27H41N9O7. Mole weight: 603.67.
Crocetin
Croceic acid can be found in the stigma of Crocus sativus L. Uses: Anticarcinogenic agents. Synonyms: Transcrocetin; trans-Crocetin; 8,8'-Diapocarotenedioic acid. Grades: >98%. CAS No. 27876-94-4. Molecular formula: C20H24O4. Mole weight: 328.4.
CroCin
Crocin is a water-soluble carotenoid pigment in saffron (Crocus sativus L.) with anti-inflammatory, antioxidant, anti-apoptosis, anti-asthma, anti-cancer, anti-allergy, relaxation of smooth muscle and hypolipidemic effects. Crocin inhibits tumor necrosis factor (TNF) α-induced pheochromocytoma (PC12) apoptosis by regulating the mRNA expression of Bcl-2 family proteins, which trigger downstream signals that ultimately lead to caspase-3 activation and subsequent cell death. Uses: Antioxidant, anticancer. Synonyms: Crocin (Gardenia Fruits Extract); β-D-Glucopyranose, 6-O-β-D-glucopyranosyl-, 1,1'-[(2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-tetramethyl-2,4,6,8,10,12,14-hexadecaheptaenedioate]; 8,8'-Diapo-ψ,ψ-carotenedioic acid, bis(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl) ester; all-trans-Crocetin di-β-D-gentiobiosyl ester; Crocetin bis(gentiobiosyl) ester; Crocetin di(β-D-gentiobiosyl) ester; Crocetin di-β-gentiobiosyl ester; Crocetin digentiobioside; Crocin 1; Crocin 4; Crocin A; Crocin I; Kiriyasu Oil Yellow GY; trans-Crocetin di(β-D-gentiobiosyl) ester; Trans-crocin-1; trans-Crocin-1; Trans-crocin-4; α-Crocin. Grades: >98%. CAS No. 42553-65-1. Molecular formula: C44H64O24. Mole weight: 976.96.
Crocin II
Crocin II is a hydrophilic carotenoid found in the flowers crocus and gardenia. It shows therapeutic effect on various human disorders such as atheroslerosis. Uses: Atheroslerosis. Synonyms: Crocetingentiobiosylglucosyl ester; Tricrocin; Crocin 2; b-D-Glucopyranose 6-O-b-D-glucopyranosyl-1-[(2E,4E,6E,8E,10E,12E,14E)-b-D-glucopyranosyl 2,6,11,15-tetramethyl-2,4,6,8,10,12,14-hexadecaheptaenedioate]. Grades: >98%. CAS No. 55750-84-0. Molecular formula: C38H54O19. Mole weight: 814.42.
Cromolyn
Cromolyn, a chromene derivative, could be used in the treatmen of allergic an a aast cell stabiliser. Uses: Anti-asthmatic agents. Synonyms: Cromolyn; Cromoglicic acid; Cromoglycate; Acido cromoglicico; Acide cromoglicique. Grades: 98%. CAS No. 16110-51-3. Molecular formula: C23H16O11. Mole weight: 468.37.
CRT0066101
CRT0066101 is a small-molecule protein kinase D (PKD) inhibitor that suppresses PDK1, PDK2 and PDK3 (PDK1: IC50 = 1 nM; PDK2: IC50 = 2.5 nM; PDK3: IC50 = 2 nM). Studies in vivo showed that CRT0066101 inhibited pancreatic cancer growth. Synonyms: Phenol, 2-[4-[[(2R)-2-aminobutyl]amino]-2-pyrimidinyl]-4-(1-methyl-1H-pyrazol-4-yl)-, hydrochloride (1:2); (R)-2-(4-((2-Aminobutyl)amino)pyrimidin-2-yl)-4-(1-methyl-1H-pyrazol-4-yl)phenol dihydrochloride; 2-(4-{[(2R)-2-Aminobutyl]amino}pyrimidin-2-yl)-4-(1-methyl-1H-pyrazol-4-yl)phenol dihydrochloride; CRT 0066101; CRT-0066101; CRT0066101 dihydrochloride. Grades: ≥95%. CAS No. 1883545-60-5. Molecular formula: C18H22N6O.2HCl. Mole weight: 411.33.
CRT0066101 hydrochloride
CRT0066101 is an inhibitor of all three PKD isoforms (IC50s = 1, 2.5, and 2 nM for PKD1, PKD2, and PKD3, respectively). It exhibits selectivity for PKD against a panel of >90 protein kinases, including PKCα, PKBα, MEK, ERK, c-Raf, c-Src, and c-Abl. Synonyms: Phenol, 2-[4-[[(2R)-2-aminobutyl]amino]-2-pyrimidinyl]-4-(1-methyl-1H-pyrazol-4-yl)-, hydrochloride (1:3); (R)-2-(4-((2-Aminobutyl)amino)pyrimidin-2-yl)-4-(1-methyl-1H-pyrazol-4-yl)phenol trihydrochloride; 2-(4-{[(2R)-2-Aminobutyl]amino}pyrimidin-2-yl)-4-(1-methyl-1H-pyrazol-4-yl)phenol trihydrochloride. Grades: ≥95%. CAS No. 1781742-22-0. Molecular formula: C18H22N6O.3HCl. Mole weight: 447.79.
CRT 0105950
CRT 0105950 is a potent inhibitor of LIMK1/2 (IC50 = 0.3 and 1 nM at LIMK 1 and 2, respectively). It disrupts microtubule organization, inhibits phosphorylation of cofilin and increases α-tubulin acetylation in vitro. Synonyms: 4-[[5-[3-(2-Chloro-4-methylphenyl)-4-pyridinyl]-2-thiazolyl]amino]phenol. Grades: ≥98% by HPLC. CAS No. 1661845-86-8. Molecular formula: C21H16ClN3OS. Mole weight: 393.89.
CRT5
CRT5 is a pyrazine benzamide that prevents activation of all three isoforms of PKD (IC50s = 1, 2, and 1.5 nM for PKD1, PKD2, and PKD3, respectively) in endothelial cells treated with VEGF. Synonyms: CRT0066051. Grades: ≥98%. CAS No. 1034297-58-9. Molecular formula: C28H30N4O2. Mole weight: 454.6.
Cryptochlorogenic acid
Cryptochlorogenic acid is an isomer of chlorogenic acid and possesses antioxidant properties, which is extracted from the flowerbud of Lonicera japonica Thunb. Uses: Cryptochlorogenic acid is used as an antibiotic, and antioxidant agent. Synonyms: 4-O-(3,4-Dihydroxycinnamoyl)-D-quinic acid; 3,4-Dihydroxycinnamic acid 4-carboxy-2,4,6-trihydroxycyclohexyl ester; 4-Caffeoylquinic acid; Quinic acid 4-O-caffeate; 4-Dicaffeoylquinic Acid. Grades: >98%. CAS No. 905-99-7. Molecular formula: C16H18O9. Mole weight: 354.31.
CS 2100
CS 2100 has been found to be a S1P1 agonist and exhibit activities in animal's adjuvant-induced arthritis model. Synonyms: CS-2100; CS 2100; CS2100. 1-[[4-Ethyl-5-[5-(4-phenoxyphenyl)-1,2,4-oxadiazol-3-yl]-2-thienyl]methyl]-3-azetidinecarboxylic acid. Grades: ≥97% by HPLC. CAS No. 913827-99-3. Molecular formula: C25H23N3O4S. Mole weight: 461.53.
CS 476
AT-308 is a synthetic bio-active chemical as an oral hypoglycaemic agent. Uses: An oral hypoglycaemic agent. Synonyms: CS 476; CS-476; CS476; NOVO CS 476; NSC 302998. N-(4-(2-(2,3-Dihydrobenzo(b)furan-7-carboxamido)ethyl)benzenesulfonyl)-N'-cyclohexylurea. Grades: ≥98%. CAS No. 41177-35-9. Molecular formula: C24H29N3O5S. Mole weight: 471.57.
CS 722
CS 722 is a neuromuscular blocking agent and centrally acting muscle relaxant. It exerts its muscle relaxant action by affecting both the supraspinal structure and the spinal cord. In Oct 2000, Phase II for Hypertonia in Japan was discontinued. Uses: Muscle hypertonia. Synonyms: CS 722; CS-722; CS722. 4-Chloro-2-(2-hydroxy-3-morpholinopropyl)-5-phenyl-4-isoxazolin-3-one. Grades: 98%. CAS No. 144886-17-9. Molecular formula: C16H20Cl2N2O4. Mole weight: 375.25.
CSF1R-IN-1
CSF1R-IN-1 is a CSF1R inhibitor with IC50 of 0.5 nM. Synonyms: CSF1R Inhibitor Compound 22; CHEMBL4084391; EX-A5045; HY-101774. Grades: 98%. CAS No. 2095849-04-8. Molecular formula: C25H20F3N5O2. Mole weight: 479.5.
CS-M1995
CS-M1995 is a 4'-Azidocytidine analogue. It can inhibit Hepatitis C virus replication. Uses: Cs-m1995 can inhibit hepatitis c virus replication. Synonyms: CS-M1995; CS M1995; CSM1995; Nucleoside-Analog-1;6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one, 2-azido-2,3,3a,9a-tetrahydro-3-hydroxy-2-(hydroxymethyl)-, (2R,3S,3aS,9aR)-;(2R,3S,3aS,9aR)-2-azido-3-hydroxy-2-(hydroxymethyl)-3a,9a-dihydro-3H-furo[1,2][1,3]oxazolo[3,4-a]pyrimidin-6-one. Grades: >98 %. CAS No. 876707-99-2. Molecular formula: C9H9N5O5. Mole weight: 267.20.
CS-M1996
CS-M1996 is a 4'-Azidocytidine analogue. It can inhibit Hepatitis C virus replication. Uses: Cs-m1996 can inhibit hepatitis c virus replication. Synonyms: CS-M1996; CS M1996; CSM1996; 2,4(1H,3H)-PyriMidinedione, 1-(4-C-azido-β-D-arabinofuranosyl)- (9CI);Nucleoside-Analog-2;1-[(2R,3S,4S,5R)-5-azido-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione. Grades: >98 %. CAS No. 876708-01-9. Molecular formula: C9H11N5O6. Mole weight: 285.21.
CTLA-4 inhibitor
CTLA-4 inhibitor is an inhibitor of CTLA-4, an immune checkpoint negatively regulating T cell function. CTLA-4 is thought to regulate T-cell proliferation early in an immune response, primarily in lymph nodes. Synonyms: MDK24720; MDK 24720; MDK-24720; CTLA-4 inhibitor. 2-(4-Fluorophenyl)-6-methyl-4-(3-(trifluoromethyl)phenyl)-1,2-dihydrodipyrazolo[3,4-b:3',4'-d]pyridin-3(6H)-one; EX-A913. CAS No. 635324-72-0. Molecular formula: C21H13F4N5O. Mole weight: 427.363.
CTOP
CTOP has been found to be an effective and selective μ opioid receptor antagonist and could be used in the treatment of pain. Synonyms: D-Phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-ornithyl-L-threonyl-3-mercapto-L-valyl-L-threoninamide Cyclic (2?7)?-Disulfide. Grades: 98%. CAS No. 103429-31-8. Molecular formula: C50H67N11O11S2. Mole weight: 1062.28.
CTPI-2
CTPI-2 is the third-generation mitochondrial citrate carrier SLC25A1 inhibitor with a KD of 3.5 μM. Synonyms: SLC25A1 Inhibitor CTPI-2; Benzoic Acid, 2-[[(4-Chloro-3-Nitrophenyl)Sulfonyl]Amino]-; 2-[(4-Chloro-3-Nitrophenyl)Sulphonyl]Anthranilic Acid. Grades: 98%. CAS No. 68003-38-3. Molecular formula: C13H9ClN2O6S. Mole weight: 356.74.
CTX-0294885
CTX-0294885 is a novel broad-spectrum kinase inhibitor. CTx-0294885 exhibits inhibitory activity against a broad range of kinases in vitro. Use of a quantitative proteomics approach confirmed the selectivity of CTx-0294885-bound beads for kinase enrichment. Large-scale CTx-0294885-based affinity purification followed by LC-MS/MS led to the identification of 235 protein kinases from MDA-MB-231 cells, including all members of the AKT family that had not been previously detected by other broad-spectrum kinase inhibitors. CTx-0294885 represents a powerful new reagent for analysis of kinome signaling networks that may facilitate development of targeted therapeutic strategies. Synonyms: CTX-0294885; CTX 0294885; CTX0294885; CTx 0294885. Grades: 98%. CAS No. 1439934-41-4. Molecular formula: C22H24ClN7O. Mole weight: 437.93.
CTX-0294885 hydrochloride
CTX-0294885 hydrochloride is the hydrochloride salt of CTX-0294885 which displays high affinity toward an extensive range of kinases. The evaluation of the binding profile of CTx-0294885 in MDA-MB-231 cells by quantitative MS demonstrated its selective properties as a kinase enrichment reagent. Synonyms: 2-[[5-chloro-2-(4-piperazin-1-ylanilino)pyrimidin-4-yl]amino]-N-methylbenzamide;hydrochloride; CTX-0294885 hydrochloride; CTX 0294885 hydrochloride; CTX0294885 hydrochloride. Molecular formula: C22H25Cl2N7O. Mole weight: 474.39.
C-Type Natriuretic Peptide-22 (human, porcine, rat) trifluoroacetate salt
C-Type natriuretic peptide-22 is an endogenous peptide which has diverse biological activities. CNP-22 acts as a selective agonist of natriuretic peptide receptors (NPRs) 2 and 3 (Kds = 7, 10.8, and >500,000 pM for NPR2, 3, and 1, respectively). The 22 amino acid sequence corresponds to residues 105-126 of its precursors prepro CNP, pro CNP, and CNP-53. Synonyms: CNP-22; glycyl-L-leucyl-L-seryl-L-lysylglycyl-L-cysteinyl-L-phenylalanylglycyl-L-leucyl-L-lysyl-L-leucyl-L-α-aspartyl-L-arginyl-L-isoleucylglycyl-L-seryl-L-methionyl-L-serylglycyl-L-leucylglycyl-L-cysteine cyclic (6?22)-disulfide trifluoroacetate salt. Grades: ≥95%. Molecular formula: C93H157N27O28S3·xCF3COOH. Mole weight: 2197.60.
CU CPT 4a
CU CPT 4a is a selective TLR3 inhibitor (IC50 = 3.44 μM in RAW 264.7 cells). Synonyms: CU CPT 4a; CU-CPT-4a; CUCPT4a; N-[(3-Chloro-6-fluorobenzo[b]thien-2-yl)carbonyl]-D-phenylalanine. CAS No. 1279713-77-7. Molecular formula: C18H13ClFNO3S. Mole weight: 377.82.
Cucurbit[7]uril
Cucurbit[7]uril is a cyclic organic molecule that consists of seven glycoluril units connected by methylene bridges. Cucurbit[7]uril is a pharmaceutical excipient, which can be used in the fields of drug delivery, catalysis, and sensing. Synonyms: 2, 18:3, 17-Dimethano-2, 3, 4a, 5a, 6a, 7a, 8a, 9a, 10a, 11a, 12a, 13a, 14a, 15a, 17, 18, 19a, 20a, 21a, 22a, 23a, 24a, 25a, 26a, 27a, 28a, 29a, 30a-octacosaazabispentaleno[1''''', 6''''':5'''', 6'''', 7'''']cycloocta[1'''', 2'''', 3'''':3''', 4''']pentaleno[1''', 6''':5'', 6'', 7'']cycloocta[1'', 2'', 3'':3', 4']pentaleno[1', 6':5, 6, 7]cycloocta[1, 2, 3-cd:1', 2', 3'-gh]pentalene-1, 4, 6, 8, 10, 12, 14, 16, 19, 21, 23, 25, 27, 29-tetradecone, tetradecahydro-, stereoisomer; stereoisomer of Tetradecahydro-2, 18:3, 17-dimethano-2, 3, 4a, 5a, 6a, 7a, 8a, 9a, 10a, 11a, 12a, 13a, 14a, 15a, 17, 18, 19a, 20a, 21a, 22a, 23a, 24a, 25a, 26a, 27a, 28a, 29a, 30a-octacosaazabispentaleno[1''''', 6''''':5'''', 6'''', 7'''']cycloocta[1'''', 2'''', 3'''':3''', 4''']pentaleno[1''', 6''':5'', 6'', 7'']cycloocta[1'', 2'', 3'':3', 4']pentaleno[1', 6':5, 6, 7]cycloocta[1, 2, 3-cd:1', 2', 3'-gh]pentalene-1, 4, 6, 8, 10, 12, 14, 16, 19, 21, 23, 25, 27, 29-tetradecone; Carrier CB 7; CB 7; CB-7; CB7. Grades: 95%. CAS No. 259886-50-5. Molecular formula: C42H42N28O14. Mole weight: 1162.96.
Cucurbit[8]uril
Cucurbit[8]uril is a remarkably versatile host molecule utilized in a diverse range of drug delivery and catalysis applications. Its unique ability to selectively bind various drug and biomolecule targets with high avidity illustrates its significant potential as a candidate for targeted drug delivery. Furthermore, the catalytic efficacy and promising sensor properties of Cucurbit[8]uril make it a valuable asset in the field of chemical synthesis and detection of diverse analytes. Synonyms: CB[8]; Cucurubituril(8). Grades: 95%. CAS No. 259886-51-6. Molecular formula: C48H48N32O16. Mole weight: 1329.10.
Cucurbitacin C
Cucurbitacin C is a cucurbitacin. Grades: > 95%. CAS No. 5988-76-1. Molecular formula: C32H48O8. Mole weight: 560.72.