BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Cucurbitacin D | Source from rhizomes of Hemsleya amabilis Diels. It might be a new therapeutic option for the treatment of endometrial and ovarian cancers, also may be a potential therapeutic agent for β-hemoglobinopathies, including sickle cell anemia and β-thalassemia. And it induces apoptosis through caspase-3 and phosphorylation of JNK in hepatocellular carcinoma cells. Uses: Antitumor, resistance to chemical carcinogens, protect liver. Synonyms: 17-[(3E)-1,5-Dihydroxy-1,5-dimethyl-2-oxohex-3-en-1-yl]-2,16-dihydroxy-4,4,9,14-tetramethylestr-5-ene-3,11-dione. Grades: >98%. CAS No. 3877-86-9. Molecular formula: C30H44O7. Mole weight: 516.67. |  |
| Cucurbitacin I | Cucurbitacin I is a triterpenoid compound which is extracted from some Cucurbitaceae related plants. It was found to be a potential selective inhibitor of JAK2 / STAT3 showing various of possible Pharmacological activities.(IC50 = 500 nM when suppresses l. Uses: Cucurbitacin i is a triterpenoid compound and has been found to be a potential selective inhibitor of jak2 / stat3. Synonyms: Cucurbitacin I; Elatericin B; Cucurbitacine (I); 1,2-Dehydroelatericin A; CHEBI:3947. Grades: ≥95%. CAS No. 2222-7-3. Molecular formula: C30H42O7. Mole weight: 514.65. | |
| Cucurbitacin Q1 | Cucurbitacin Q1 is a terpenoid isolated from hemsleya amabilis. Synonyms: 25-acetylcucurbitacin F; 25-O-Acetylcucurbitacin F. Grades: 0.98. CAS No. 99530-82-2. Molecular formula: C32H48O8. Mole weight: 560.7. | |
| Curvalicin-28c | Curvalicin-28c is an antibacterial peptide isolated from Lactobacillus curvatus. It has activity against gram-positive bacteria. Synonyms: Bioactive peptide 3; BAP3; Asn-Ile-Pro-Gln-Leu-Thr-Pro-Thr-Pro. Grades: 97.7%. Molecular formula: C44H73N11O14. Mole weight: 980.13. | |
| Cussosaponin C | Cussosaponin C is extracted from the herb of Pulsatilla chinensis (Bge.) Regel. Synonyms: Cussosaponin C; 366814-42-8; CHEMBL446867; AKOS037514604; FS-7116; HY-107310; CS-0027956. Grades: >98%. CAS No. 366814-42-8. Molecular formula: C59H96O25. Mole weight: 1205.4. | |
| CU-T12-9 | CU-T12-9 is a potent small-molecule agonist of TLR1/2 (EC50 = 52.9 nM). Synonyms: Benzenamine, N-methyl-4-nitro-2-[4-[4-(trifluoromethyl)phenyl]-1H-imidazol-1-yl]-; CU T12 9; CUT129; N-Methyl-4-nitro-2-[4-[4-(trifluoromethyl)phenyl]-1H-imidazol-1-yl]benzenamine; CU-T 12-9. Grades: ≥95%. CAS No. 1821387-73-8. Molecular formula: C17H13F3N4O2. Mole weight: 362.31. | |
| CVT10216 | CVT10216 is a potent and selective, reversible inhibitor of aldehyde dehydrogenase 2 (ALDH2) with IC50 value of 29nM, thereby inhibiting dopamine synthesis. It is active in suppressing alcohol and cocaine use, and anxiety. It has been shown to produce anxiolytic effects in four different rodent models, including a model of repeated alcohol withdrawal-induced anxiety. It increases acetaldehyde after alcohol gavage and inhibits 2-bottle choice alcohol intake in heavy drinking rodents. It prevents operant self-administration and eliminates cue-induced reinstatement of alcohol seeking. It also prevents alcohol-induced increases in NAc DA without changing basal levels. Uses: Cvt10216 is active in suppressing alcohol and cocaine use, and anxiety. Synonyms: CVT-10216; CVT 10216; CVT10216. 3-[[[3-[4-[(Methylsulfonyl)amino]phenyl]-4-oxo-4H-chromen-7-yl]oxy]methyl]benzoic acid;GS 455534. Grades: >98 %. CAS No. 1005334-57-5. Molecular formula: C24H19NO7S. Mole weight: 465.48. | |
| CVT-12012 | CVT-12012 is a bio-active chemical compound and is highly potent in a human cell-based (HEPG2) SCD assay with IC50 value of 6nM. Synonyms: CVT-12012; CVT 12012; CVT12012; 2-Hydroxy-N- (2- (3-methyl-2-oxo-7- ( ( (3- (trifluoromethyl) phenyl) methyl) amino) -1, 2-dihydroquinoxalin-1-yl) ethyl) acetamide. Grades: 95%. CAS No. 1018675-35-8. Molecular formula: C21H21F3N4O3. Mole weight: 434.41. | |
| CVT-2551 | CVT-2551, a piperazineacetamide derivative, could have been useful in some biological studies. Synonyms: CVT-2551; CVT 2551; CVT2551; RS-89961; RS 89961; RS89961; 1-Piperazineacetamide, 4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)-N-(2-(hydroxymethyl)-6-methylphenyl)-. Grades: 98%. CAS No. 172430-44-3. Molecular formula: C24H33N3O5. Mole weight: 443.54. | |
| CVT-2759 | CVT-2759 is a potential partial agonist of A(1)-ADORs, may be used to slow AV nodal conduction. Uses: Adenosine a1 receptor agonists. Synonyms: CVT-2759; CVT 2759; CVT2759; UNII-42E8N8RC9Z. Adenosine, N-((3R)-tetrahydro-3-furanyl)-, 5'-(ethylcarbamate). Grades: ≥98%. CAS No. 342419-10-7. Molecular formula: C17H24N6O6. Mole weight: 408.17. | |
| CVT-3248 | CVT-3248, a piperazineacetamide derivative, could be probably effective in some biological studies. Synonyms: L58PM3303I; CVT-3248; CVT 3248; CVT3248; RS-101647; RS 101647; RS101647; 1-Piperazineacetamide, N-(2-(hydroxymethyl)-6-methylphenyl)-. Grades: 98%. CAS No. 172430-50-1. Molecular formula: C14H21N3O2. Mole weight: 263.34. | |
| CWHM-12 | CWHM 12 demonstrated high potency against all of the five possible β subunit binding partners (αvβ1, αvβ3, αvβ5, αvβ6 and αvβ8) in in vitro ligand-binding assays, with somewhat less potency against αvβ5 than against the other αv integrins. Treated mice with CCl4 for 3 weeks to establish fibrotic disease and then treated with CWHM 12 or vehicle for the final 3 weeks of CCl4. CWHM12 significantly reduced liver fibrosis even after fibrotic disease had been established. Similar to our findings in the liver, administration of CWHM 12 significantly inhibited progression of pulmonary fibrosis. Synonyms: CWHM12; CWHM 12; CWHM-12. Grades: >98%. CAS No. 1564286-55-0. Molecular formula: C26H32BrN5O6. Mole weight: 590.47. | |
| CX08005 | CX08005 is a competitive inhibitor of PTP1B (IC50 = 0.781 μM). CX08005 binds catalytic P-loop of enzyme. It exhibits some selectivity for PTP1B over other protein tyrosine phosphatases, except TCPTP. Synonyms: 2-[[[2- (Tetradecyl) phenyl]amino]carbonyl]benzoic acid. Grades: ≥98% by HPLC. CAS No. 1256341-22-6. Molecular formula: C28H39N04. Mole weight: 453.61. | |
| CX-6258 | CX-6258 is a potent, orally efficacious Pim 1/2/3 kinase(IC50=5 nM/25 nM/16 nM) inhibitor with excellent biochemical potency and kinase selectivity. Synonyms: (E)-5-chloro-3-((5-(3-(4-methyl-1,4-diazepane-1-carbonyl)phenyl)furan-2-yl)methylene)indolin-2-one; CX6258; CX-6258; CX 6258. CAS No. 1202916-90-2. Molecular formula: C26H24ClN3O3. Mole weight: 461.946. | |
| CX-6258 hydrochloride hydrate | The hydrochloride hydrate salt form of CX-6258, a pan-Pim kinases inhibitor, has been found to have strong antiproliferative potencies against human solid tumors and hematological malignancies. It has already been discontinued for Solid tumours. IC50: 5 n. Uses: The hydrochloride hydrate salt form of cx-6258 is a pan-pim kinases inhibitor that has been found to have strong antiproliferative potencies against human solid tumors and hematological malignancies. it has already been discontinued for solid tumours. ic5. Synonyms: CX-6258 hydrochloride hydrate; CX 6258 hydrochloride hydrate; CX6258 hydrochloride hydrate; C26H24ClN3O3.ClH.H2O; 2121AH; HY-18095A; CS-1530; W-6143; CS 1530; W 6143; CS1530; W6143. Grades: 98%. CAS No. 1353858-99-7. Molecular formula: C26H27Cl2N3O4. Mole weight: 516.42. | |
| Cy5-NHS ester | Cy5-NHS ester is a red-fluorescent probe that is reactive with primary amines on biomolecules such as proteins and nucleic acids. Synonyms: Sulfo-Cyanine5, SE (ethyl);Cyanine 5, SE; 2-[5-[1-[6-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-1,3-dihydro-3,3-dimethyl-5-sulfo-2H-indol-2-ylidene]-1,3-pentadien-1-yl]-1-ethyl-3,3-dimethyl-5-sulfo-3H-indolium, Inner Salt. Grades: 98%. CAS No. 146368-14-1. Molecular formula: C37H43N3O10S2. Mole weight: 753.882. | |
| Cy5-NHS ester tetrafluoroborate | Cy5-NHS ester is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. Synonyms: Cyanine5 NHS ester (tetrafluoroborate);Cyanine5 NHS ester tetrafluoroborate. Grades: NMR 1H, HPLC-MS (95%). CAS No. 1263093-76-0. Molecular formula: C36H42BF4N3O4. Mole weight: 667.55. | |
| Cyanidin 3-xyloside | Cyanidin 3-xyloside is an anthocyanin found in plums and berries with potential anti-cancer activity. Synonyms: 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-(D-xylopyranosyloxy)-1-benzopyrylium chloride. CAS No. 29761-24-8. Molecular formula: C20H19ClO10. Mole weight: 454.81. | |
| Cyanidin chloride | Cyanidin Chloride is a natural anthocyanidin found in a variety of fruits and vegetables. This polyphenolic compound is a flavonoid with significant antioxidant activity. Cyanidin Chloride and its glycosides have vasoprotective effects and can interfere with inflammation, carcinogenesis, obesity, and diabetes. Uses: Food pigment. Synonyms: 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxybenzopyrylium Chloride; 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-1-benzopyrylium Chloride; 3,3',4',5,7-Pentahydroxy-2-phenylbenzopyrylium Chloride; 3,3',4',5,7-Pentahydroxyflavylium Chloride; Cyanidin; Cyanidine; Cyanidol Chloride; 1-Benzopyrylium, 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-, chloride (1:1). Grades: >98%. CAS No. 528-58-5. Molecular formula: C15H11O6Cl. Mole weight: 322.70. | |
| Cyanine 3 Phosphoramidite | Cyanine 3 Phosphoramidite is a fluorescent dye used for oligonucleotide labeling. Synonyms: 2-[3-[1,3-Dihydro-1-[3-(4-methoxytriphenylmethoxy)propyl]-3,3-dimethyl-2H-indol-2-ylidene]-1-propen-1-yl]-1-[3-[N,N-diisopropylamino(2-cyanoethoxy)phosphinoxy]propyl]-3,3-dimethyl-3H-indolium. Grades: > 95%. CAS No. 718594-66-2. Molecular formula: C58H70N4O4P. Mole weight: 918.17. | |
| Cyanine 5 Phosphoramidite | Cyanine 5 Phosphoramidite is a fluorescent dye used for oligonucleotide labeling. Synonyms: 2-[5-[1,3-Dihydro-1-[3-(4-methoxytriphenylmethoxy)propyl]-3,3-dimethyl-2H-indol-2-ylidene]-1,3-pentadien-1-yl]-1-[3-[N,N-diisopropylamino(2-cyanoethoxy)phosphinoxy]propyl]-3,3-dimethyl-3H-indolium. Grades: > 95%. CAS No. 351186-76-0. Molecular formula: C60H72N4O4P. Mole weight: 944.21. | |
| Cyanocobalamin Impurity F | Cyanocobalamin Impurity F is an impurity of Vitamin B12, which is a water-soluble vitamin with a key role in the normal functioning of the brain and nervous system, and for the formation of blood. Synonyms: Vitamin B12 c-lactone; 7beta,8beta-Lactocyanocobalamin; (8β) -Co- (cyano- κC) - 8- Hydroxy- cobinic acid- abdeg- pentamide c, 8- lactone, dihydrogen phosphate (ester) , inner salt, 3'- ester with (5, 6- dimethyl- 1- α- D- ribofuranosyl- 1H- benzimidazole- κN3). Grades: > 95%. CAS No. 23208-66-4. Molecular formula: C63H85CoN13O15P. Mole weight: 1354.33. | |
| Cyanocobalamin Impurity G | Cyanocobalamin Impurity G is a Vitamin B12 derivative, a water-soluble vitamin with a key role in the normal functioning of the brain and nervous system, and for the formation of blood. Synonyms: Nb-methyl-Cobinamide Cyanide 3'-Ester with 5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole Dihydrogen Phosphate (Ester), Inner Salt; 34-Methylcyanocobalamin; Cyanocobalamin Impurity G; Nb-Methyl Cyancobalamin. Grades: >95%. CAS No. 38218-51-8. Molecular formula: C64H90CoN14O14P. Mole weight: 1369.39. | |
| Cyanocobalamin Impurity H | Cyano-8-epicobalamin is a Vitamin B12 derivative, which is a water-soluble vitamin with a key role in the normal functioning of the brain and nervous system, and for the formation of blood. Synonyms: Cyano-8-epicobalamin; (8β)-Cobinamide Cyanide 3'-Ester with 5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole Dihydrogen Phosphate (ester), inner salt, 8-Epicobalamine; 8-epi-Cyanocobalamin. Grades: > 95%. CAS No. 41325-63-7. Molecular formula: C63H88CoN14O14P. Mole weight: 1355.37. | |
| Cyanomethyl-2,3,4,6-tetra-O-acetyl-a-D-thiomannopyranoside | Cyanomethyl-2,3,4,6-tetra-O-acetyl-a-D-thiomannopyranoside, a chemical reagent utilized in glycosyl cyanide manufacture for chemical synthesis, exhibits excelling properties. In addition to its primary use, it can also facilitate the research on acetal glycoside formation. As such, its scientific significance for advancing academic knowledge and research cannot be overstated. Synonyms: 2-[(2,3,4,6-Tetra-O-acetyl-alpha-D-mannopyranosyl)thio]acetonitrile. CAS No. 61145-39-9. Molecular formula: C16H21NO9S. Mole weight: 403.40. | |
| Cyantraniliprole | Cyantraniliprole is an insecticide of the ryanoid class. It has activity against pests such as Diaphorina citri. Synonyms: Exirel; Cyazpyr; HGW-86; HGW 86; HGW86. Grades: >98%. CAS No. 736994-63-1. Molecular formula: C19H14BrClN6O2. Mole weight: 473.71. | |
| Cyclandelate | Cyclandelate is an effective inhibitor of rat hepatic acycloenzyme A: cholesterol acyltransferase (ACAT) with IC50 of 80 μM. Uses: Vasodilator agents. Synonyms: BS 572; BS572; BS-572. Grades: >98%. CAS No. 456-59-7. Molecular formula: C17H24O3. Mole weight: 276.37. | |
| Cyclic citrullinated peptide | Cyclic citrullinated peptide is a synthetic cyclic peptide combined with the amino acid citrullinated. Can be used to diagnose rheumatoid arthritis. Grades: >95%. | |
| Cyclocephaloside II | Cyclocephaloside II - a natural remedy with immense potential for use in treating Alzheimer's disease. Its efficacy lies in its role as an effective inhibitor of amyloid beta peptides. These peptides are widely believed to play a pivotal part in the neural degradation characteristic of Alzheimer's disease. In addition, studies have indicated that Cyclocephaloside II possesses antioxidant and anti-inflammatory properties, which may grant it protective effects against the ravages of oxidative stress within the brain. Synonyms: (3beta,6alpha,16beta,20R,24S)-3-[(4-O-Acetyl-beta-D-xylopyranosyl)oxy]-20,24-epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl beta-D-glucopyranoside. Grades: >98%. CAS No. 215776-78-6. Molecular formula: C43H70O15. Mole weight: 827.0. | |
| Cycloguanil | Cycloguanil is a dihydrofolate reductase inhibitor. Synonyms: 1-(4-chlorophenyl)-6,6-dimethyl-1,3,5-triazine-2,4-diamine. CAS No. 516-21-2. Molecular formula: C11H14ClN5. Mole weight: 251.718. | |
| Cyclohexadecanone | Cyclohexadecanone (CAS# 2550-52-9 ) is a useful research chemical. Synonyms: Homoexaltone. CAS No. 2550-52-9. Molecular formula: C16H30O. Mole weight: 238.41. | |
| Cyclo(L-Leu-L-Pro) | Cyclo (-Leu-Pro) is a cyclic dipeptide containing leucine and proline. Synonyms: cyclo(Leu-Pro); Cyclo(L-leucyl-L-prolyl). Grades: ≥95%. CAS No. 2873-36-1. Molecular formula: C11H18N2O2. Mole weight: 210.3. | |
| Cyclopentakis(1,4-butylene Terephthalate) | Synonyms: PBT pentamer. CAS No. 82298-33-7. Molecular formula: C60H60O20. Mole weight: 1101.1. | |
| Cyclopentanol, 2-cyclopentylidene- | Cyclopentanol, 2-cyclopentylidene- is a useful research chemical. Synonyms: 1,1'-bi(cyclopentyliden)-2-ol. Grades: 95 %. CAS No. 6261-30-9. Molecular formula: C10H16O. Mole weight: 152.23. | |
| Cyclophosphamide | Low-dose preferentially deplets Treg cells; An alkylating agent of the nitrogen mustard type with antineoplastic and immunosuppressive activities; Phase I-II. Uses: Broad-spectrum antineoplastic agents. cyclophosphamide can be used in the treatment of leukemia and other cancers. Synonyms: Cytoxan; Clafen; Neosar; CTX; 2-Bis(2-chloroethyl)aminotetrahydro-2H-1,3,2-oxazophosphorine-2-oxide; N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide. CAS No. 50-18-0. Molecular formula: C7H15Cl2N2O2P. Mole weight: 261.09. | |
| Cyclophosphamide monohydrate | Cyclophosphamide monohydrate is a nitrogen mustard alkylating agent, which attaches the alkyl group to the guanine base of DNA. It is used to treat cancers and autoimmune diseases. Synonyms: Cyclophosphamide hydrate; Cytoxan; Endoxon. CAS No. 6055-19-2. Molecular formula: C7H15Cl2N2O2P·H2O. Mole weight: 279.1. | |
| Cyclopropyl 2-Fluorophenyl Diketone | Cas No. 1391054-37-7. | |
| Cyclo(Pro-Trp) | Grades: >98%. CAS No. 67889-75-2. Molecular formula: C16H17N3O2. Mole weight: 283.32. | |
| Cyclo(RGDyK) Trifluoroacetate | Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM. Synonyms: Cyclo (RGDyK); Cyclo RGDyK; Cyclo(RGDyK) trifluoroacetate. Grades: >98%. CAS No. 250612-42-1. Molecular formula: C31H43F6N9O12. Mole weight: 847.71. | |
| Cyclosporin A | Cyclosporin A (Cyclosporine A) is an immunosuppressant that binds to cyclophilins, inhibiting calcineurin activity with an IC50 of 7 nM. It also inhibits CD11a/CD18 adhesion molecules. Synonyms: Ciclosporin; cyclosporine; Cyclosporine A; Sandimmun; Cyclosporin; Neoral; Ciclosporine; Sandimmune; Ramihyphin A. Grades: 98%. CAS No. 59865-13-3. Molecular formula: C62H111N11O12. Mole weight: 1202.61. | |
| Cyclotetrakis(1,4-butylene Terephthalate) | Cyclotetrakis(1,4-butylene terephthalate), an innovative biocompatible polyester, holds immense potential for medical applications, including drug delivery and tissue engineering. Its biodegradability and non-toxicity have shown promise as a robust material for biomedical purposes. Nonetheless, its full therapeutic potency requires extensive research and evaluation. CAS No. 29278-72-6. Molecular formula: C48H48O16. Mole weight: 880.9. | |
| Cyclotris(1,4-butylene Terephthalate) | Cyclotris(1,4-butylene terephthalate) is a polymer which demonstrates promise for use in sophisticated bio-applications e.g. drug delivery systems and tissue engineering. Exhibiting favorable biocompatibility properties, it may be utilized for encapsulating medication and providing targeted release to precise physiological areas. In addition to this, researchers have explored its potential in cardiovascular disease treatments; it may also be employed as a scaffold for regenerating tissue. Synonyms: PBT Cyclic Trimer. CAS No. 63440-94-8. Molecular formula: C36H36O12. Mole weight: 660.7. | |
| Cyclovirobuxine D | Cyclovirobuxine D is an active compound extracted from Buxus microphylla, which has been used for treating acute myocardial ischemia. Cyclovirobuxine D induces autophagy and attenuates the phosphorylation of Akt and mTOR. Cyclovirobuxine D inhibits cell proliferation of gastric cancer cells through suppression of cell cycle progression and inducement of mitochondria-mediated apoptosis. Uses: Anti- oxidative/anticancer. Synonyms: Cyclovirobuxine D; Bebuxine; CVB-D; CVB D; CVBD; NSC 91722; NSC-91722; NSC91722. Grades: >98%. CAS No. 860-79-7. Molecular formula: C26H46N2O. Mole weight: 402.66. | |
| Cyflumetofen | Cyflumetofen is a pesticide that was developed as an acaricide to control spider mites. Synonyms: 2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate. CAS No. 400882-07-7. Molecular formula: C24H24F3NO4. Mole weight: 447.4. | |
| Cyhalofop | Cyhalofop(Cyhalofop acid) is a recently registered herbicide from the aryloxyphenoxy propionate group in India to control a wide range of grass weed species at various growth stages in rice crop. Synonyms: Cyhalofop acid. Grades: >98%. CAS No. 122008-78-0. Molecular formula: C16H12FNO4. Mole weight: 301.27. | |
| CYM 50260 | CYM 50260 has been found to be a S1P4 agonist. Synonyms: CYM-50260; CYM 50260; CYM50260. 2-Chloro-3-[2-(2,4-dichlorophenoxy)ethoxy]-6-(fluoromethyl)pyridine. Grades: ≥98% by HPLC. CAS No. 1355026-60-6. Molecular formula: C14H11Cl3FNO2. Mole weight: 350.60. | |
| CYM 50308 | CYM 50308 has been found to be an effective and selective S1P4 agonist. Synonyms: CYM-50308; CYM 50308; CYM50308. (2Z,5Z)-5-[[1-(2,4-Difluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]methylene]-2-[(2-methoxyethyl)imino]-3-methyl-4-thiazolidinone. Grades: ≥98% by HPLC. CAS No. 1345858-76-5. Molecular formula: C20H21F2N3O2S. Mole weight: 405.46. | |
| CYM 50358 hydrochloride | CYM 50358 hydrochloride is a potent S1P4 antagonist (IC50 = 25 nM). It is selective for S1P4 against S1P1, S1P2, S1P3 and S1P5 receptors. Synonyms: N-[(4-(Aminomethyl)-2,6-dimethylphenyl]-5-(2,5-dichlorophenyl)-2-furancarboxamide hydrochloride. Grades: ≥97% by HPLC. CAS No. 1781750-72-8. Molecular formula: C20H18Cl2N2O2·HCl. Mole weight: 425.74. | |
| CYM 50769 | CYM 50769 has been found to be a non-peptide antagonist of neuropeptide W/B receptor 1. Synonyms: CYM 50769; CYM50769; CYM-50769; 5-Chloro-2-(9H-fluoren-9-yl)-4-(4-methoxyphenoxy)-3(2H)-pyridazinone. Grades: ≥98% by HPLC. CAS No. 1421365-63-0. Molecular formula: C24H17ClN2O3. Mole weight: 416.86. | |
| CYM 5442 | The hydrochloride salt form of CYM 5442, which has been found to be an effective and selective S1P1 agonist. Synonyms: CYM-5442; CYM 5442; CYM5442. 2-(4-(5-(3,4-Diethoxyphenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl amino) ethanol hydrochloride. Grades: ≥98% by HPLC. CAS No. 1094042-01-9. Molecular formula: C23H27N3O4. Mole weight: 409.5. | |
| CYM 5442 hydrochloride | CYM 5442 hydrochloride is a potent and selective S1P1 agonist in vitro (EC50 = 1.35 nM). It activates S1P1-mediated p42/p44 MAPK phosphorylation in CHO-K1 cells transfected with S1P1. And it induces acute lymphopenia in mice. Synonyms: 2-(4-(5-(3,4-Diethoxyphenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl amino) ethanol hydrochloride. Grades: ≥98% by HPLC. CAS No. 1783987-80-3. Molecular formula: C23H27N3O4·HCl. Mole weight: 445.94. | |
| CYM 5520 | CYM 5520 is a selective allosteric agonist of S1P2 (EC50 = 0.48 μM). It is selective for S1P2 receptors over a panel of 29 other receptors and transporters. Synonyms: 1-[2-[2,5-Dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethyl]-1,6-dihydro-6-oxo-3-pyridinecarbonitrile. Grades: ≥95%. CAS No. 1449747-00-5. Molecular formula: C21H19N3O2. Mole weight: 345.4. | |
| CYM-5541 | CYM-5541, also called as ML249, is a selective sphingosine-1-phosphate receptor 3 (S1P3) allosteric agonist (EC50 = 72-132 nM) that less effectively activates S1P1 (EC50 = 28-38 μM) and does not disrupt S1P2, S1P4, and S1P5 as well as a panel of other receptors, ion channels and transporters. Synonyms: N,N-dicyclohexyl-5-cyclopropyl-1,2-oxazole-3-carboxamide; CYM-5541; CYM 5541; CYM5541; N,N-dicyclohexyl(5-cyclopropylisoxazol-3-yl)carboxamide. CAS No. 945128-26-7. Molecular formula: C19H28N2O2. Mole weight: 316.44. | |
| Cynarin | Cynarin, phenolic compound, is an antichoke agent with a variety of biological activities including antioxidant, antihistamic and antiviral activities. Cynarin is used in weight loss and lipid-lowering formulas, liver protection and anti-alcoholic drugs, etc. Synonyms: Cyclohexanecarboxylic acid, 1,3-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-4,5-dihydroxy-, (1R,3R,4S,5R)-; (1R,3R,4S,5R)-1,3-Bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-4,5-dihydroxycyclohexanecarboxylic acid; Cinnamic acid, 3,4-dihydroxy-, 1-carboxy-4,5-dihydroxy-1,3-cyclohexylene ester; Cyclohexanecarboxylic acid, 1,3-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-4,5-dihydroxy-, (1R,3R,4S,5R)-; Cyclohexanecarboxylic acid, 1,3-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-4,5-dihydroxy-, [1R-(1α, 3α, 4α, 5β)]-; Cynarine; 1,3-Dicaffeoylquinic acid; 1,5-Dicaffeoylquinic acid; Cinarin; Cinarine. Grades: >98%. CAS No. 30964-13-7. Molecular formula: C25H24O12. Mole weight: 516.45. | |
| Cynaropikrin | Cynaropikrin, a polyphenolic compound, is a sesquiterpene lactone in C. scolymus. Cynaropikrin is the bitter principle in artichoke and is, therefore, an important compound in the chemical profiling of the plant. Cynara scolymus L. (Asteraceae), commonly found in southern Europe and the USA, is cultivated as a vegetable and medicinal plant artichoke leaves are traditionally used for treatment of bile and liver diseases. Pharmacological studies have shown that extracts of the plant significantly increase choleresis (C. scolymus is used for treatment of dyspeptic syndrome) and reduce blood cholesterol, mainly because of inhibition of hepatocellular de novo cholesterol biosynthesis. Synonyms: 2-Propenoic acid, 2-(hydroxymethyl)-, dodecahydro-8-hydroxy-3,6,9-tris(methylene)-2-oxoazuleno[4,5-b]furan-4-yl ester, [3aR-(3aα, 4α, 6aα, 8β, 9aα, 9bβ)]-; Cynaropicrin (6CI); Azuleno[4,5-b]furan, 2-propenoic acid deriv. Grades: > 98%. CAS No. 35730-78-0. Molecular formula: C19H22O6. Mole weight: 346.37. | |
| CysLT1 Antagonist Q8 | CysLT1 antagonist Q8 is a cysteinyl leukotreine (CysLT1) receptor antagonist inhibiting angiogenesis in transgenic fluorescent zebrafish, and human microvascular endothelial cell (HMEC-1) proliferation, tubule formation, and migration. CysLT1 antagonist Q8 exhibits antiangiogenic effect in a VEGF-independent in vitro model of angiogenesis and an additive antiangiogenic response with bevacizumab. Synonyms: Q8 hydrochloride; Q 8 hydrochloride; Q-8 hydrochloride; (E)-2-(2-Quinolin-2-yl-vinyl)-benzene-1,4-diol Hydrochloride. Grades: 99%. CAS No. 1541762-55-3. Molecular formula: C17H14ClNO2. Mole weight: 299.75. | |
| Cystamine dihydrochloride | Cystamine dihydrochloride is the dihydrochloride salt of cystamine, which is an organic disulfide that inhibits tissue transglutaminase (TGM2) with an IC50 value of approximately 2.5 mM. It is orally available, and decreases aggregated and cross-linked huntingtin in transfected cells. It is neuroprotective in mouse models of Huntington's disease. It has exhibited suppressive effects against HIV replication in infected human cells. It could extend survival and improve motor performance in transgenic HD mice. It inhibits caspase 3, increases intracellular glutathione, and reduces inflammation in a rat model of inflammatory bowel disease. Uses: Enzyme inhibitors. Synonyms: 2-(2-aminoethyldisulfanyl)ethanamine; dihydrochloride. Grades: > 97 %. CAS No. 56-17-7. Molecular formula: C4H14Cl2N2S2. Mole weight: 225.20. | |
| Cysteinyl-3M3SH | Cysteinyl-3M3SH is an intermediate in the bacterial biotransformation of the odourless physiological malodour precursor Cys-Gly-3M3SH. Cys-Gly-3M3SH is actively transported by the di-/tri-peptide transporter (DtpT) along with the movement of protons. Once inside the cell the terminal glycine is cleaved by a dipeptidase (PepA) to release Cys-3M3SH. Synonyms: Cys-3M3SH. Molecular formula: C10H21NO3S. Mole weight: 235.34. | |
| CYT-1010 | CYT-1010 is a μ-opioid receptor agonist found in patent WO2013173730A2. Synonyms: CYT1010; CYT 1010. Grades: 98%. CAS No. 213769-33-6. Molecular formula: C35H40N6O5. Mole weight: 624.7. | |
| Cyt387 | Cyt387 is an ATP-competitive inhibitor of JAK1 and JAK2 (IC50 = 11 nM and 18 nM respectively). It has been shown to decrease cancer stem cell associated tumor burden in a mouse model of human ovarian cancer. It is commonly used as a therapy for myelofibrosis. Uses: An orally bioavailable small-molecule inhibitor of janus kinases 1 and 2 (jak1/2) with potential antineoplastic activity (ic50s = 11 and 18 nm, respectively). Synonyms: Momelotinib; N-(Cyanomethyl)-4-[2-[[4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]benzamide; CYT 11387; CYT 387; CYT-387; CYT387; CYT-0387; GS 0387. Grades: >98%. CAS No. 1056634-68-4. Molecular formula: C23H22N6O2. Mole weight: 414.46. | |
| Cytostatin sodium salt | Cytostatin is a potent and selective inhibitor of protein phosphatase 2A (PP2A; IC50 = 29 nM against the catalytic subunit), but it doesn't have effect against PP1, PP2B, or PP5. Synonyms: 2H-Pyran-2-one, 5,6-dihydro-6-[(1S,4S,5S,6S,7Z,9Z,11E)-6-hydroxy-1,5-dimethyl-4-(phosphonooxy)-7,9,11-tridecatrien-1-yl]-5-methyl-, sodium salt (1:1), (5S,6S)-; 2H-Pyran-2-one, 5,6-dihydro-6-[(1S,4S,5S,6S,7Z,9Z,11E)-6-hydroxy-1,5-dimethyl-4-(phosphonooxy)-7,9,11-tridecatrienyl]-5-methyl-, monosodium salt, (5S,6S)-; (+)-Cytostatin sodium salt; NSC 675266 sodium salt. Grades: ≥75%. CAS No. 457070-06-3. Molecular formula: C21H32NaO7P. Mole weight: 450.44. | |
| D149 Dye | D149 Dye is an organic dye for highly efficient solid-state dye-sensitized solar cells. Uses: D149 dye can be used as an organic dye to enhance the absorption of dye sensitized solar cells (dsscs). Synonyms: D149; D 149; D-149; Indoline dye D149. Grades: >98%. CAS No. 786643-20-7. Molecular formula: C42H35N3O4S3. Mole weight: 741.94. | |
| DA-3003-2 | DA-3003-2 is an inhibitor of Cdc25 phosphatase (IC50 = 0.82 μM for human recombinant Cdc25B) and it shows antiproliferative activity. Synonyms: NSC 663285; 7-chloro-6-[[2-(4-morpholinyl)ethyl]amino]-5,8-quinolinedione. Grades: ≥98%. CAS No. 383907-47-9. Molecular formula: C15H16ClN3O3. Mole weight: 321.8. | |
| DAA-1106 | DAA-1106, with anxiolytic effects in mice, is a selective ligand for peripheral benzodiazepine receptor (PBR) and a selective agonist at the peripheral benzodiazepine receptor. Synonyms: N-[(2,5-dimethoxyphenyl)methyl]-N-(5-fluoro-2-phenoxyphenyl)acetamide (11C)DAA1106 DAA 1106 DAA-1106 DAA1106 N-(2,5-dimethoxybenzyl)-N-(5-fluoro-2-isophenoxyphenyl)acetamide. CAS No. 220551-92-8. Molecular formula: C23H22FNO4. Mole weight: 395.42. | |
| DABCYL-Lys-HCoV-SARS Replicase Polyprotein 1ab (3235-3246)-Glu-EDANS | Synonyms: DABCYL-Lys-pp1ab (3235-3246)-Glu-EDANS (Human coronavirus) (strain SARS); DABCYL-Lys-ORF1AB (3235-3246)-Glu-EDANS (Human coronavirus) (strain SARS). CAS No. 730985-86-1. Molecular formula: C95H141N25O24S2. Mole weight: 2081.42. | |
| Dabigatran | Dabigatran is a very potent anticoagulant, shows that the terminal phenyl can be substituted by the more hydrophilic 2-pyridyl group without substantial loss of activity. Uses: Benzimidazoles; beta-alanine/analogs & derivatives. Synonyms: BIBR 953; BIBR953; BIBR-953. Grades: >98%. CAS No. 211914-51-1. Molecular formula: C25H25N7O3. Mole weight: 471.51. | |
| Dabigatran Etexilate Impurity 1 | An impurity of Dabigatran Ethyl Ester, a nonpeptide, direct thrombin inhibitor. Synonyms: O-Desethyl O-Isopropyl Dabigatran Etexilate. Grades: > 95%. CAS No. 1610758-19-4. Molecular formula: C35H43N7O5. Mole weight: 641.78. | |
| Dabigatran Etexilate Impurity 2 | O-(2-Ethylbutyl) Dabigatran Ethyl Ester is an impurity of Dabigatran Ethyl Ester, a nonpeptide, direct thrombin inhibitor. Synonyms: O-(2-Ethylbutyl) Dabigatran Ethyl Ester; N- [ [2- [ [ [4- [ [ [ (2-Ethylbutoxy) carbonyl] amino] iminomethyl] phenyl] amino] methyl] -1-methyl-1H-benzimidazol-5-yl] carbonyl] -N-2-pyridinyl-β -Alanine Ethyl Ester. Grades: > 95%. CAS No. 1610758-20-7. Molecular formula: C34H41N7O5. Mole weight: 627.73. | |
| Dabigatran Etexilate N-Oxide Inner Salt | Dabigatran Etexilate N-Oxide is a metabolite of Dabigatran Etexilate, an oral anticoagulant and direct thrombin inhibitor. Synonyms: N- [ [2- [ [ [4- [ [ [ (Hexyloxy) carbonyl] amino] iminomethyl] phenyl] amino] methyl] -1-methyl-1H-benzimidazol-5-yl] carbonyl] -N- (1-oxido-2-pyridinyl) -β -Alanine Ethyl Ester. Grades: > 95%. CAS No. 1381757-44-3. Molecular formula: C34H41N7O6. Mole weight: 643.73. | |
| Dabigatran ethyl AcOH Salt | Synonyms: Ethyl 3-(2-(((4-carbamimidoylphenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate acetate. CAS No. 1188263-64-0. Molecular formula: C29H33N7O5. Mole weight: 559.627. | |
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