BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Dipsanoside B | Dipsanoside B is a compound of the iridoids found in the roots of Dipsacus asperoides. Grades: >98%. CAS No. 889678-64-2. Molecular formula: C66H90O37. Mole weight: 1475.409. |  |
| Dipyrazino[2,3-f:2,3-h]quinoxaline-2,3,6,7,10,11-hexacarbonitrile | Dipyrazino[2,3-f:2,3-h]quinoxaline-2,3,6,7,10,11-hexacarbonitrile (CAS# 105598-27-4 ) is a useful research chemical. Synonyms: Hexaazatriphenylenehexacabonitrile; HAT-CN; Dipyrazino[2,3-f:2',3'-h]quinoxalinehexacarbonitrile. Grades: 95 %. CAS No. 105598-27-4. Molecular formula: C18N12. Mole weight: 384.27. | |
| Dirlotapide | Dirlotapide is a drug used to treat obesity in dogs works as a gut-selective microsomal triglyceride transfer protein (MTTP or MTP) inhibitor. Uses: Mttp inhibitor. Synonyms: Dirlotapide; Slentrol; CP 742033; CP-742033; CP742033; CP-742,033.5-((4'-Trifluoromethyl-biphenyl-2-carbonyl)amino)-1H-indole-2-carboxylic acid benzylmethyl carbamoylamide. Grades: ≥95%. CAS No. 481658-94-0. Molecular formula: C40H33F3N4O3. Mole weight: 674.71. | |
| disodium 6-[(2,4-dimethyl-6-sulphonatophenyl)azo]-5-hydroxynaphthalene-1-sulphonate | disodium 6-[(2,4-dimethyl-6-sulphonatophenyl)azo]-5-hydroxynaphthalene-1-sulphonate (CAS# 3257-28-1 ) is a useful research chemical. Synonyms: 1-Naphthalenesulfonic acid, 6-[2-(2,4-dimethyl-6-sulfophenyl)diazenyl]-5-hydroxy-, sodium salt (1:2). Grades: 95 %. CAS No. 3257-28-1. Molecular formula: C18H14N2Na2O7S2. Mole weight: 480.417. | |
| Disodium pamidronate | Pamidronate disodium pentahydrate is a nitrogen-containing bisphosphonate, used to prevent osteoporosis. Grades: >98%. CAS No. 109552-15-0. Molecular formula: C3H9NNa2O7P2. Mole weight: 279.03. | |
| (±)-Disparlure | (±)-Disparlure is a pheromone that can be used in agriculture. Synonyms: (±)-cis-Disparlure; 7,8-cis-Epoxy-2-methyloctadecane; Disparlure; Atralymon; Epoxan. Grades: 95 %. CAS No. 29804-22-6. Molecular formula: C19H38O. Mole weight: 282.512. | |
| Disufenton | Disufenton, a benzenesulfonate compound, has been found to be a free radical scavenger that was once studied in acute ischaemic stroke therapy as a neuroprotective agent. Synonyms: Disufenton; NXY-059; NXY 059; NXY059; AC1OC7NJ; N-tert-butyl-1-(2,4-disulfophenyl)methanimine oxide; CHEMBL1206050; N-tert-butyl-1-(2,4-disulfophenyl)methanimine oxide. Grades: 98%. CAS No. 168021-77-0. Molecular formula: C11H15NO7S2. Mole weight: 337.36. | |
| Disufenton Sodium | The sodium salt form of Disufenton, a benzenesulfonate compound, has been found to be a free radical scavenger that was once studied in acute ischaemic stroke therapy as a neuroprotective agent. Synonyms: sodium (Z)-4-((tert-butyloxidoazanylidene)methyl)benzene-1,3-disulfonate; NXY059; NXY 059; NXY-059; CXY 059; CXY059; CXY-059; OKN007; OKN-007; OKN 007; ARL 16556; ARL16556; ARL-16556; CPI-22; CPI22; CPI 22; Disufenton sodium. Grades: 98%. CAS No. 168021-79-2. Molecular formula: C11H13NNa2O7S2. Mole weight: 381.33. | |
| di-tert-butylphenyl phenyl phosphate | Di-tert-butylphenyl phenyl phosphate, a phosphorus-containing flame retardant, is frequently utilized in the manufacturing of plastics, textiles, and electronic devices. Additionally, it serves as a polyvinyl chloride stabilizer and as a thermal stabilizer in lubricating oils. However, some studies have revealed that it has the potential to cause endocrine disruption and neurotoxicity, which has prompted certain countries to restrict its usage. Synonyms: Bis(tert-butylphenyl)phenyl Phosphate; Phosphoric acid, bis[(1,1-dimethylethyl)phenyl] phenyl ester; Bis(o-tert-butylphenyl) phenyl phosphate; Di-(t-butylphenyl) phenyl phosphate; bis(t-butylphenyl) phenyl phosphate. Grades: ≥90%. CAS No. 65652-41-7. Molecular formula: C26H31O4P. Mole weight: 438.50. | |
| di-Tetradecylamine | di-Tetradecylamine (CAS# 17361-44-3 ) is a useful research chemical. Synonyms: N-Tetradecyl-1-tetradecanamine; Alamine 205; Dimyristylamine; Di-n-tetradecylamine; N,N-Ditetradecylamine; NSC 91530; Ditetradecylamine. CAS No. 17361-44-3. Molecular formula: C28H59N. Mole weight: 409.77. | |
| Dithranol | Dithranol is a hydroxyanthrone, anthracene derivative, medicine applied to the skin of people with psoriasis. Synonyms: Anthralin; Batridol; Dithranol; NSC 629313; NSC-629313; NSC629313. Grades: >98%. CAS No. 1143-38-0. Molecular formula: C14H10O3. Mole weight: 226.23. | |
| Divalproex sodium | Divalproex Sodium, consisting of a compound of sodium valproate and valproic acid in a 1:1 molar relationship in an enteric coated form, is a HDAC inhibitor used in the treatment of epilepsy. It acts via binding to and inhibiting gamma-aminobutyric acid (GABA) transaminase. Uses: The treatment of epilepsy. Synonyms: NSC 694279; NSC-694279; NSC694279; EP 475; EP475; EP-475; Valproate semisodium; Depakote; Epival; Depakote ER. Grades: >98%. CAS No. 76584-70-8. Molecular formula: C16H31NaO4. Mole weight: 310.41. | |
| Dizocilpine | Dizocilpine is a potent N-methyl-D-aspartate (NMDA) receptor antagonist with Ki of 30.5 nM. Synonyms: MK-801; MK 801; MK801; (5S)-5-methyl-10,11-dihydro-5H-5,10-epiminodibenzo[a,d][7]annulene. Grades: ≥98%. CAS No. 77086-21-6. Molecular formula: C16H15N. Mole weight: 221.303. | |
| DJ-V 159 | DJ-V 159 is a GPRC6A agonist and it reduces blood glucose levels in mice in vivo. Synonyms: N1, N3-Bis (4-cyano-3- (trifluoromethyl) phenyl) isophthalamide; DJ-V-159; DJ-V159; BCP30173; EX-A3017. Grades: ≥98%. Molecular formula: C24H12F6N4O2. Mole weight: 502.37. | |
| D,L-1?-Acetoxychavicol acetate | Cas No. 52946-22-2. | |
| D,L-3-Indolylglycine | D, L-3-Indolylglycine, similar to Tryptophan, is an unnatural amino acid. Uses: An unnatural amino acid. Synonyms: Amino-(1H-indol-3-yl)acetic acid; 2-amino-2-(1H-indol-3-yl)acetic acid. Grades: ≥95%. CAS No. 6747-15-5. Molecular formula: C10H10N2O2. Mole weight: 190.2. | |
| DL-AP4 | DL-AP4 has been found to be a broad spectrum EAA ligand as well as an NMDA glutamate receptor antagonist. Uses: Excitatory amino acid agonists. Synonyms: AP4; AP 4; AP-4; DL-2-Amino-4-phosphonobutyric acid. Grades: ≥98% by HPLC. CAS No. 20263-07-4. Molecular formula: C4H10NO5P. Mole weight: 183.10. | |
| DL-AP4 Sodium salt | The sodium salt form of DL-AP4, which has been found to be a broad spectrum EAA ligand. Synonyms: DL-2-Amino-4-phosphonobutyric acid sodium salt. Grades: ≥99% by HPLC. CAS No. 1263093-79-3. Molecular formula: C4H9NNaO5P. Mole weight: 205.08. | |
| DL-Carnitine | Carnitine regulates fatty acid transport in mitochondria, elevates serum carnitine fractions. Uses: Regulates fatty acid transport in mitochondria, elevates serum carnitine fractions. Synonyms: (3-carboxy-2-hydroxypropyl)trimethyl-,hydroxide,innersalt,dl-ammoniu;1-propanaminium,3-carboxy-2-hydroxy-n,n,n-trimethyl-,hydroxide,innersalt,;DL-CARNITINE;CARNITIN;(±)-(3-carboxy-2-hydroxypropyl)trimethylammonium hydroxide;1-Propanaminium, 3-carboxy-2-h. Grades: ≥95%. CAS No. 406-76-8. Molecular formula: C7H15NO3. Mole weight: 161.20. | |
| DL-erythro-PPMP hydrochloride | DL-erythro-PPMP is an inactive stereoisomer of DL-threo-PPMP. It has no effect on glucosylceramide synthetase activity and is used as a negative control for DL-threo-PPMP, D-threo-PPMP, and L-threo-PPMP inhibitory effect. Synonyms: DL-erythro-1-phenyl-2-Palmitoylamino-3-morpholino-1-propanol. Grades: ≥98%. Molecular formula: C29H50N2O3·HCl. Mole weight: 511.18. | |
| DL-Glutamine | DL-Glutamine is an unnatural amino acid and could be used for general biochemical research and drug synthesis. Uses: Dl-glutamine is an unnatural amino acid and could be used for general biochemical research and drug synthesis. Synonyms: H-DL-Gln-OH. Grades: 95%. CAS No. 6899-4-3. Molecular formula: C5H10N2O3. Mole weight: 146.14. | |
| DLinDMA | DLinDMA, an ionizable cationic lipid, is a key lipid component of stable nucleic acid lipid particles (SNALPs) as a benchmark. Synonyms: 1,2-dilinoleyloxy-n,n-dimethyl-3-aminopropane; N,N-dimethyl-2,3-bis[(9Z,12Z)-octadeca-9,12-dienoxy]propan-1-amine; N,N-Dimethyl-2,3-bis(((9Z,12Z)-octadeca-9,12-dien-1-yl)oxy)propan-1-amine. Grades: >98%. CAS No. 871258-12-7. Molecular formula: C41H77NO2. Mole weight: 616.05. | |
| DLin-KC2-DMA | DLin-KC2-DMA is a cationic/ionizable lipid for siRNA delivery. DLin-KC2-DMA was formulated and characterized in SNALP and demonstrated to have in vivo activity at siRNA doses as low as 0.01 mg/kg in rodents and 0.1 mg/kg in nonhuman primates. Synonyms: 2,2-dilinoleyl-4-dimethylaminoethyl-[1,3]-dioxolane. Grades: >98%. CAS No. 1190197-97-7. Molecular formula: C43H79NO2. Mole weight: 642.09. | |
| D-Lin-MC3-DMA | D-Lin-MC3-DMA is the most potent cationic lipid that has been synthesized for lipid nanoparticles (LNPs) to deliver the siRNA. D-Lin-MC3-DMA is useful for design of lipid nanoparticles for in vitro and in vivo delivery of plasmid DNA. LNP systems containing D-Lin-MC3-DMA can be highly effective, non-toxic pDNA delivery systems for gene expression both in vitro and in vivo. Synonyms: DLin-MC3-DMA; Butanoic acid, 4-(dimethylamino)-, (10Z,13Z)-1-(9Z,12Z)-9,12-octadecadien-1-yl-10,13-nonadecadien-1-yl ester; RV 28; RV-28; O-(Z,Z,Z,Z-heptatriaconta-6,9,26,29-tetraen-19-yl)-4-(N,N-dimethylamino). Grades: >95%. CAS No. 1224606-06-7. Molecular formula: C43H79NO2. Mole weight: 642.09. | |
| DL-N-Acetylhomocysteine thiolactone | DL-N-Acetylhomocysteine thiolactone, an amino acid cysteine derivative, could be used against some liver diseases. Synonyms: Acetamide, N-(tetrahydro-2-oxo-3-thienyl)-; Butyric acid, 2-acetamido-4-mercapto-, γ-(thio lactone); N-(Tetrahydro-2-oxo-3-thienyl)acetamide; 2-Acetamido-4-mercaptobutyric acid thiolactone; DL-3-(Acetylamino)tetrahydro-2-thiophenone; AHCTL; BO 714; Citiolase; Citiolone; N-(2-Oxotetrahydrothiophen-3-yl)acetamide; N-Acetyl-DL-homocysteine thiolactone; N-Acetylhomocysteine thiolactone; NSC 22878; Thioxidrene; α-Acetamido-γ-thiobutyrolactone. Grades: ≥95%. CAS No. 1195-16-0. Molecular formula: C6H9NO2S. Mole weight: 159.21. | |
| DL-Phe(4-Ac)-OH HCl | DL-Phe(4-Ac)-OH HCl is a highly versatile chemical compound with a wide range of research applications, most notably in the fields of neurodegeneration and pain management. This modified form of phenylalanine, which features an additional acetyl group, represents a key building block for the synthesis of numerous pharmaceuticals. Thanks to its fascinating properties, including potential anti-tumor and neuroprotective effects, it has been intensively studied as a promising candidate for future drug development. Synonyms: 3-(4-Acetyl-phenyl)-2-amino-propionic acid hydrochloride. CAS No. 1360436-95-8. Molecular formula: C11H14ClNO3. Mole weight: 243.68. | |
| DL-Propargyl glycine hydrochloride | DL-Propargyl glycine (PAG) is an irreversible inhibitor of the H2S synthesizing enzyme cystathionine-γ-lyase (CSE). PAG blocks H2S synthesis activity in rat liver preparations with an IC50 value of 55 μM and abolishes the rise in plasma H2S in anaesthetized rats induced with hemorrhagic shock. Synonyms: PAG; 2-Aminopent-4-ynoic acid hydrochloride; AK323755; AK110719. Grades: ≥95%. CAS No. 16900-57-5. Molecular formula: C5H7NO2·HCl. Mole weight: 149.6. | |
| DL-Tetrahydroberberine | Tetrahydroberberine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Tetrahydroberberine is used for treatment of degenerative diseases or conditions associated with KATP channel signaling. Synonyms: 6H-Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizine, 5,8,13,13a-tetrahydro-9,10-dimethoxy-; 5,8,13,13a-Tetrahydro-9,10-dimethoxy-6H-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizine; Berberine, 9-deoxy-16,17-dihydro-; Berbine, 9,10-dimethoxy-2,3-(methylenedioxy)-; (±)-Canadine; (±)-Tetrahydroberberine; Berberine, tetrahydro-; Canadine; dl-Canadine; NSC 36351; NSC 94918; Tetrahydroberberine; Tetrahydroberineper; Tetrahydroumbellatine; Xanthopuccine. Grades: ≥95%. CAS No. 522-97-4. Molecular formula: C20H21NO4. Mole weight: 339.38. | |
| DL-threo-2-methylisocitrate | DL-threo-2-methylisocitrate is a substrate of isocitrate lyase 1(ICL1). Synonyms: DL-threo-2-methylisocitrate; 71183-66-9; alpha-methylisocitric acid; (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylic acid; methylisocitrate; Methylisocitric acid; threo-Pentaric acid, 3-carboxy-2,3-dideoxy-4-C-methyl-; SCHEMBL1533821; CHEBI:15607; DTXSID301209270; LMFA01050444; AKOS030526883; DB04072; HY-16581; C04593; Q27098140; 3-carboxy-2,3-dideoxy-4-C-methyl-L-threo-pentaric acid; rel-(2S,3R)-3-Hydroxybutane-1,2,3-tricarboxylic acid; rel-(2S,3R)-3-Hydroxybutane-1,2,3-tricarboxylicacid. Grades: >98%. CAS No. 71183-66-9. Molecular formula: C14H20O14. Mole weight: 412.3. | |
| D-Luciferin potassium salt | D-Luciferin potassium salt is a chemiluminescent substrate of firefly luciferase. Synonyms: (4S)-4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic Acid Monopotassium Salt; 4-Thiazolecarboxylic acid, 4,5-dihydro-2-(6-hydroxy-2-benzothiazolyl)-, potassium salt (1:1), (4S)-; Firefly luciferin potassium salt. Grades: 95%. CAS No. 115144-35-9. Molecular formula: C11H7KN2O3S2. Mole weight: 318.41. | |
| DMAE-NHS | As a chemiluminescent agent for direct chemiluminescence immunoanalysis, it is used for the detection and analysis of antigens, antibodies, proteins, etc. Synonyms: 6'-Dimethyl-4'-(N-succinimidyloxycarbonyl)phenyl-10-methyl-acridinium-9-carboxylate methosulfate; 9-((4-(((2,5-Dioxopyrrolidin-1-yl)oxy)carbonyl)-2,6-dimethylphenoxy)carbonyl)-10-methylacridin-10-ium methyl sulfate. Grades: ≥98%. CAS No. 115853-74-2. Molecular formula: C29H26N2O10S. Mole weight: 594.59. | |
| D-Mannosamine HCl | D-Mannosamine HCl, a paramount substance pervasively utilized in the biomedical sector, assumes a pivotal role. Its multifaceted properties enable its extensive application towards mitigating an array of ailments and disorders. Within the realm of pharmaceutical advancements, this compound assumes a critical function, facilitating the creation of antiviral pharmaceuticals, antibiotics, and anticancer therapeutics. Invaluable therapeutic implementations encompass combatting viral infections, impeding bacterial proliferation, and efficacious cancer control. The prodigious potential of D-Mannosamine HCl emerges as an instrumental asset in propelling cutting-edge biomedical exploration, thus catalyzing revolutionary drug discoveries. Synonyms: ManNH2 HCl; 2-Amino-2-deoxy-D-mannose HCl; D-Mannosamine Hydrochloride; D-Mannose, 2-amino-2-deoxy-, hydrochloride (1:1). Grades: ≥95%. CAS No. 5505-63-5. Molecular formula: C6H14ClNO5. Mole weight: 215.63. | |
| D-Mannose-6-phosphate sodium salt hydrate | D-Mannose-6-phosphate (M6P) is a phosphorylated aldohexose that has diverse physiological roles. It can be used to produce glucose as an energy source, converted to mannitol to serve as an osmolyte or metabolic store, or directed to the N-glycosylation pathway. M6P is also a ligand for both cation-dependent and -independent receptors and binds, as part of an N-glycan, to mannose receptor homology domains on other proteins. Synonyms: M6P. Grades: ≥95%. Molecular formula: C6H11O9P·2Na·xH2O. Mole weight: 304.1. | |
| D-mannuronic acid sodium | D-Mannuronic Acid Sodium Salt is a vital component used in the production of alginate hydrogels for drug delivery applications in biomedicine. It serves as a crosslinker, enhancing the stability and controlled release of various drugs to study conditions such as cancer, bacterial infections, and cardiovascular diseases. Synonyms: Sodium mannuronate; Sodium D-mannuronate; D-Mannuronic acid sodium salt. CAS No. 921-56-2. Molecular formula: C6H9NaO7. Mole weight: 216.12. | |
| D-Methionine methylsulfonium bromide | Synonyms: [(3R)-3-amino-3-carboxypropyl]-dimethylsulfanium bromide. Grades: >98%. CAS No. 212757-14-7. Molecular formula: C6H14BrNO2S. Mole weight: 244.15. | |
| Dmnq | DMNQ is a redox cycle agent. Synonyms: 2,3-Dimethoxy-1,4-Naphthoquinone. Grades: 98%. CAS No. 6956-96-3. Molecular formula: C12H10O4. Mole weight: 218.2. | |
| DMPE-PEG | Synonyms: 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-n-PEG. Grades: >95%. CAS No. 474922-82-2. Molecular formula: (C2H4O)nC35H68NO10P. Mole weight: 755.0. | |
| DMU-2105 | DMU-2105 is a potent and selective CYP1B1 inhibitor with IC50 of 10 nM and 742 nM for CYP1B1 and CYP1A1, respectively. Synonyms: DMU 2105; DMU2105. Grades: 98%. CAS No. 1031063-36-1. Molecular formula: C18H13NO. Mole weight: 259.3. | |
| DMU2139 | DMU2139 is a potent and specific CYP1B1 inhibitor with IC50 of 9 nM and 795 nM for CYP1B1 and CYP1A1, respectively. Grades: 98%. CAS No. 1821143-80-9. Molecular formula: C19H15NO2. Mole weight: 289.3. | |
| D-myo-Inositol-1,2,3,4-tetraphosphate sodium salt | D-myo-Inositol-1,2,3,4-tetraphosphate (Ins(1,2,3,4)-P4) is one of the many inositol phosphate (InsP) isomers that could act as small, soluble second messengers in the transmission of cellular signals. Ins(1,2,3,4)-P4 exhibits agonist activity at the Ins(1,4,5)-P3 receptor expressed in CHO cells where it induces Ca2+ mobilization, making it nearly 180-fold less effective than Ins(1,4,5)-P3 in the same assay. Grades: ≥98%. Molecular formula: C6H12O18P4·4Na. Mole weight: 588. | |
| D-myo-Inositol-1,2,3,6-tetraphosphate sodium salt | D-myo-Inositol-1,2,5,6-tetraphosphate sodium salt is an invaluable component, exhibiting tremendous potential in research of an array of afflictions such as cancer, diabetes and neurodegenerative disorders. Its role as a pivotal signaling entity manifests in its remarkable influence on cellular mechanisms encompassing growth, metabolism and inflammation. Grades: ≥98%. Molecular formula: C6H12O18P4·4Na. Mole weight: 588. | |
| D-myo-Inositol-1,2,4,5-tetraphosphate sodium salt | Ins(1,2,4,5)P4 is one of the many inositol phosphate (InsP) isomers that act as small, soluble second messengers in the transmission of cellular signals. Grades: ≥98%. Molecular formula: C6H12O18P4·4Na. Mole weight: 588. | |
| D-myo-Inositol-1,3,4,5,6-pentaphosphate ammonium salt | Inositol-1,3,4,5,6-pentaphosphateis one of the many inositol phosphate isomers that act as small, soluble second messengers in the transmission of cellular signals. It can be interconverted with Ins(3,4,5,6)P4 by a 1-kinase/1-phosphatase cycle, as well as with Ins(1,4,5,6)P4 in a 3-kinase/3-phosphatase cycle. Grades: >98%. Molecular formula: C6H7O21P5·10NH4. Mole weight: 750.36. | |
| D-myo-Inositol-1,3,4,5,6-pentaphosphate sodium salt | The phosphatidylinositol 3-kinase (PI3K)/Akt signal transduction pathway plays critical roles in cell growth and proliferation making it an attractive target for anticancer agents. Inositol-1,3,4,5,6-pentaphosphate (Ins(1,3,4,5,6)P5) is one of the many inositol phosphate isomers that act as small, soluble second messengers in the transmission of cellular signals. It exhibits antiangiogenic activity in vitro, blocking capillary tube formation of HUVEC, as well as antitumor effects against cancer xenografts in nude mice. Grades: ≥98%. Molecular formula: C6H12O21P5·5Na. Mole weight: 689.96. | |
| D-myo-Inositol-2,3,5,6-tetraphosphate sodium salt | D-myo-inositol-2,3,5,6-tetraphosphate sodium salt is produced from Ins(1,2,3,5,6)P5 by a minor enzymatic phytate degradation pathway. And it is moderately effective in opening calcium channels than Ins(1,4,5)P3. Synonyms: 2,3,5,6-IP4 sodium salt; Ins(2,3,5,6)-P4 sodium salt; D-myo-inositol-2,3,5,6-tetrakis(dihydrogen phosphate), tetrasodium salt. Grades: ≥98%. Molecular formula: C6H12O18P4·4Na. Mole weight: 588. | |
| D-myo-Inositol-2,3,5-triphosphate ammonium salt | D-myo-Inositol-2,3,5-triphosphate ammonium salt is a member of the inositol phosphate (InsP) family of second messengers which play an important role in the transmission of cellular signals. Ins(2,3,5)P3 ammonium salt is 500-fold less potent than Ins(1,4,5)-P3 at initiating Ca2+ release when injected into Xenopus oocytes. Synonyms: Ins(2,3,5)P3 ammonium salt; 2,3,5-IP3 ammonium salt; D-myo-inositol-2,3,5-tris(dihydrogen phosphate), triammonium salt. Grades: ≥98%. Molecular formula: C6H12O15P3·3NH4. Mole weight: 522.3. | |
| D-myo-Inositol-2,4,5-triphosphate sodium salt | D-myo-Inositol-2,4,5-triphosphate sodium salt is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-biphosphate. Ins(2,4,5)P3 acts as a partial agonist at rat hepatic IP3 receptors, exhibiting 65% of the maximal Ca2+ response obtained with Ins(1,4,5)P3. Synonyms: Ins(2,4,5)P3 sodium salt; 2,4,5-IP3 sodium salt; D-myo-inositol-2,4,5-tris(hydrogen phosphate), trisodium salt. Grades: ≥98%. Molecular formula: C6H12O15P3·3Na. Mole weight: 486. | |
| D-myo-Inositol-2,5,6-triphosphate sodium salt | Ins(2,5,6)P3 is a less potent inducer of calcium release from permeabilized rat basophilic leukemia cells with an EC50 value of 110 μM compared to Ins(1,4,5)P3, which has an EC50 value of 0.17 μM. Synonyms: Ins(2,5,6)P3 sodium salt; 2,5,6-IP3 sodium salt; D-myo-inositol-2,5,6-tris(dihydrogen phosphate), trisodium salt. Grades: ≥98%. Molecular formula: C6H12O15P3·3Na. Mole weight: 486. | |
| D-myo-Inositol-3,4,5-triphosphate sodium salt | D-myo-Inositol-3,4,5-triphosphate (Ins(3,4,5)-P3) is a structural analog of Ins(1,4,5)-P3 and also a member of the inositol phosphate (InsP) cell signaling family of molecules. D-myo Ins(3,4,5)-P3 is 200-fold less potent than D-myo Ins(1,4,5)-P3 at initiating Ca++ release when injected into Xenopus oocytes. Ins(3,4,5)-P3 binds to Type 1, 2, and 3 subtypes of the rat recombinant IP3 receptor with Ki values of 3-11 μM. Synonyms: Ins(3,4,5)-P3; 3,4,5-IP4; D-myo-inositol-3,4,5-tris(hydrogen phosphate), trisodium salt. Grades: ≥98%. Molecular formula: C6H12O15P3·3Na. Mole weight: 486. | |
| D-NMAPPD | D-NMAPPD is an inhibitor of ceramidase. It induces cell death in SW403 colon adenocarcinoma cells in a time- and concentration-dependent manner but doesn't have effect on viability of rat hepatocytes, Kupffer cells, or sinusoidal endothelial cells when used at a concentration of 100 mM. It also increases intracellular ceramide accumulation and cytochrome C release and induces apoptosis in SW403 cells. Synonyms: (1R,2R)-B13; CAY10466; N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-tetradecanamide. Grades: ≥98%. CAS No. 35922-06-6. Molecular formula: C23H38N2O5. Mole weight: 422.6. | |
| DNP-INT | DNP-INT is a quinone analog that inhibits electron transport in plants by competitively inhibiting plastoquinol oxidation by binding at the Qo site of cytochrome b6f (Kd = 1.4 nM). It inhibits electron flow from water to NADP or methylviologen by 50 and 100% when used at concentrations of 0.5 or 5 μM, respectively. Synonyms: 2-(2,4-dinitrophenoxy)-3-iodo-4-methyl-1-(1-methylethyl)-5-nitro-benzene; 2-Iodo-6-isopropyl-3-methyl-2',4,4'-trinitrodiphenyl ether; 4-(2,4-dinitrophenoxy)-3-iodo-2-methyl-1-nitro-5-propan-2-ylbenzene. Grades: ≥98%. CAS No. 69311-70-2. Molecular formula: C16H14IN3O7. Mole weight: 487.2. | |
| Dnp-Pro-Leu-Gly-Leu-Trp-Ala-DArg-NH2 | Dnp-Pro-Leu-Gly-Leu-Trp-Ala-DArg-NH2, a peptide utilized for biological research, is an exemplary agent for evaluating proteolytic activity and inhibitor effects. Notably, its potential in disease treatment, encompassing cancer and inflammation, has put it at the forefront of therapeutic development. In addition to its promising therapeutic properties, Dnp-Pro-Leu-Gly-Leu-Trp-Ala-DArg-NH2 may serve as a vital diagnostic tool for identifying pertinent enzymes within biological samples, providing otherwise unattainable insights for investigative purposes. Synonyms: N-(2,4-DINITROPHENYL)-PRO-LEU-GLY-LEU-TRP-ALA-D-ARG AMIDE; MMP SUBSTRATE, FLUOROGENIC; 360 MMP FRET SUBSTRATE I; DNP-PRO-LEU-GLY-LEU-TRP-ALA-D-ARG-NH2; DNP-PLGLWAR-NH2; N-(2,4-dinitrophenyl)-pro-leu-gly-leu-*trp-ala-D-. Grades: 98%. CAS No. 121282-17-5. Molecular formula: C45H64N14O11. Mole weight: 977.08. | |
| Docarpamine | Docarpamine is a prodrug of dopamine. Synonyms: docarpamine; 74639-40-0; Tanadopa; TA-870; UNII-RPQ57D8S72. Grades: 95%. CAS No. 74639-40-0. Molecular formula: C21H30N2O8S. Mole weight: 470.54. | |
| Docosanedioic acid | Behenic acid, or docosanedioic acid, a saturated fatty acid, is an effective emollient in the cosmetics industry due to its remarkable moisturizing properties. Behenic acid's therapeutic potential is another aspect of interest, as it has been researched for the treatment of various maladies, including multiple sclerosis and Parkinson's disease. Moreover, it is demonstrated to have a positive impact on chondrogenesis, which is vital for the formation of cartilage tissue due to its exceptional proliferative force. Synonyms: docosanedioicacid; Docosanedioicacid; Felogenicacid; Phellogenicacid; 1,22-Docosanedioicacid; 505-56-6. Grades: 95%. CAS No. 505-56-6. Molecular formula: C22H42O4. Mole weight: 370.57. | |
| Docosatrienoic Acid | Docosatrienoic acid is a rare ω-3 fatty acid, not readily detected in normal phospholipid PUFA pools. Docosatrienoic acid inhibits LTB4 binding to pig neutrophil membranes (Ki= 5 μM). Synonyms: docosa-13,16,19-trienoic acid. CAS No. 28845-86-5. Molecular formula: C22H38O2. Mole weight: 334.54. | |
| Dodecyl 2-(N,N-dimethylamino)propionate hydrochloride | Dodecyl 2-(N,N-dimethylamino)propionate hydrochloride, a quaternary ammonium compound, finds extensive use as a phase transfer catalyst to create novel drugs and chemical substances. It also serves as a surfactant in biomedical experiments that enhances drug solubility and effectiveness. Its exceptional attribute of crossing the blood-brain barrier suggests future potential in neurological and psychiatric therapies. Synonyms: Alanine, N,N-dimethyl-, dodecyl ester, hydrochloride (1:1); Dodecyl 2-dimethylaminopropanoate Hydrochloride; DDAIP Hydrochloride; Dodecyl N,N-dimethylalaninate hydrochloride (1:1). Grades: 95%. CAS No. 259685-49-9. Molecular formula: C17H36ClNO2. Mole weight: 321.93. | |
| Dodecyl b-D-glucopyranoside | Dodecyl b-D-glucopyranoside: A surfactant commonly used in the biomedical industry for various applications. It is utilized in drug formulation and gene delivery systems due to its ability to solubilize hydrophobic drugs. Additionally, it plays a crucial role in cell lysis, protein extraction, and enzyme stabilization. It is also employed in biochemistry and biotechnology research for the purification and analysis of glycoproteins and glycolipids. Synonyms: Dodecyl glucoside; n-Dodecyl b-D-glucopyranoside. CAS No. 59122-55-3. Molecular formula: C18H36O6. Mole weight: 348.47. | |
| Dodecylphosphocholine | Dodecylphosphocholine is a structural analogue of lauroyl lysophosphatidylcholine which is more stable to hydrolytic degradation. Synonyms: dodecyl phosphocholine; n-Dodecylphosphocholine; FOS-Choline 12; FC-12. Grades: >99%. CAS No. 29557-51-5. Molecular formula: C17H38NO4P. Mole weight: 351.46. | |
| Dofequidar | Dofequidar, also known as MS-209, is a quinolone-derived sphingomyelin synthase inhibitor that blocks P-glycoprotein and multidrug resistance-associated protein-1, is under development by Schering for the potential treatment of multidrug resistant tumors. Dofequidar was found to sensitizes cancer stem-like side population cells to chemotherapeutic drugs by inhibiting ABCG2/BCRP-mediated drug export. Uses: Antineoplastic agents. Synonyms: Dofequidar. CAS No. 129716-58-1. Molecular formula: C30H31N3O3. Mole weight: 481.596. | |
| Dofequidar fumarate | Dofequidar fumarate, a quinoline derivative, is a multidrug resistance (MDR)-reversing quinoline derivative by inhibiting ABCB1/P-gp, ABCC1/MDR-associated protein 1, or both. It has potential to treat advanced and recurrent breast cancer and non-small lun. Synonyms: MS-209; MS 209; MS209. CAS No. 153653-30-6. Molecular formula: C34H35N3O7. Mole weight: 597.66. | |
| Dolastatin 10 | Dolastatin 10 is a potent antimitotic peptide from a marine animal, strongly inhibiting microtubule assembly. Uses: Adcs cytotoxin. Synonyms: DLS 10; NSC 376128; Dolastatin-10; DLS-10; DLS10; NSC376128; NSC-376128; L-Valinamide, N,N-dimethyl-L-valyl-N-[2-methoxy-4-[2-[1-methoxy-2-methyl-3-oxo-3-[[2-phenyl-1-(2-thiazolyl)ethyl]amino]propyl]-1-pyrrolidinyl]-1-(1-methylpropyl)-4-oxobutyl]-N-methyl-,[2S-[1[1R*(R*),2S*],2R*[1S*,2S*,3(R*)]]]-. Grades: >98%. CAS No. 110417-88-4. Molecular formula: C42H68N6O6S. Mole weight: 785.09. | |
| Donepezil | Donepezil, also called Aricept, a centrally acting reversible acetyl cholinesterase inhibitor that the FDA has also approved for the treatment of moderate to severe Alzheimer's disease. It readily crosses the blood-brain barrier to reduce the breakdown of acetylcholine by increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis by acetylcholinesterase. Synonyms: 2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one; (±)-E 2020; 1-Benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]piperidine; Neuripezil; Tonizep; 2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one; Aricept; HSDB 7743; HSDB7743; HSDB-7743; 1-benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine hydrochloride; 2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one; Eranz; Aricept ODT; donepezilo; donepezilum; CHEMBL502; donepezil hydrochloride; donepezilium oxalate trihydrate; E 2020; E-2020; E2020; 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one; (RS)-2-[(1-BENZYL-PIPERIDIN-4-YL)METHYL]-5,6-DIMETHOXYINDAN-1-ONE. Grades: > 98%. CAS No. 120014-06-4. Molecular formula: C24H29NO3. Mole weight: 379.49. | |
| Donepezil Alkene Pyridine N-Oxide | Donepezil Alkene Pyridine N-Oxide is an impurity of Donepezil, a medication for the treatment of Alzheimer's disease. Synonyms: 1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-[(1-oxido-4-pyridinyl)methylene]-; 2,3-Dihydro-5,6-dimethoxy-2-[(1-oxido-4-pyridinyl)methylene]-1H-inden-1-one; 4-[(5,6-dimethoxy-1-indanon-2-ylidene)methyl]pyridine N-oxide; 4-((5,6-Dimethoxy-1-oxo-1H-inden-2(3H)-ylidene)methyl)pyridine 1-oxide. Grades: ≥95%. CAS No. 896134-06-8. Molecular formula: C17H15NO4. Mole weight: 297.31. | |
| Donepezil EP Impurity G | Donepezil EP Impurity G is one of Donepezil impurities. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. Synonyms: YT2G5HE97P. CAS No. 2452407-72-4. Molecular formula: C24H27NO3. Mole weight: 377.48. | |
| Donepezil Impurity 3 | Donepezil impurity. Synonyms: 3-Keto Donepezil; 2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-1H-indene-1,3(2H)-dione; 5,6-Dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-indene-1,3(2H)-dione. Grades: > 95%. CAS No. 1023500-88-0. Molecular formula: C24H27NO4. Mole weight: 393.48. | |
| Donepezil Open-Ring Keto Acid | Donepezil Open-Ring Keto Acid is an impurity of Donepezil, a medication for the treatment of Alzheimer's disease. Synonyms: 2-[3-(1-Benzylpiperidin-4-yl)-2-oxopropyl]-4,5-dimethoxybenzoic acid. CAS No. 197010-25-6. Molecular formula: C24H29NO5. Mole weight: 411.498. | |
| Donepezil related compound A | (2E)-Dehydrodonepezil is a derivative of Donepezil. Synonyms: (E)-2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methylene]-1H-Inden-1-one; 2-(1-Benzylpiperidin-4-ylmethylidene)-5,6-dimethoxyindan-1-one. Grades: > 95%. CAS No. 145546-80-1. Molecular formula: C24H27NO3. Mole weight: 377.49. | |
| Dooku 1 | Dooku 1 reversibly blocks Yoda1 activity (IC50 = ~1.5 μM) and has no effect on constitutive Piezo1 channel activity, but it can antagonize Yoda1-induced Piezo1 activation in endothelial cells, and inhibits Yoda1-induced Ca2+-entry in vitro. Synonyms: 2-[(2,6-Dichlorobenzyl)thio)-5-(1H-pyrrol-2-yl)-1,3,4-oxadiazole. Grades: ≥98% by HPLC. Molecular formula: C13H9Cl2N3OS. Mole weight: 326.2. | |
| Dopamine HCl | Dopamine HCl is a catecholamine neurotransmitter present in a wide variety of animals, and a dopamine D1-5 receptors agonist. Synonyms: 4-(2-Aminoethyl)-1,2-benzenediol Hydrochloride; 4-(2-Aminoethyl)pyrocatechol Hydrochloride; 2-(3,4-Dihydroxyphenyl)ethyl-1,1,2,2-amine Hydrochloride. Grades: >98%. CAS No. 62-31-7. Molecular formula: C8H12ClNO2. Mole weight: 189.64. | |
| DOPE | DOPE (1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine) is a membrane phospholipid emulsifier to improve the transfection of DNA. Synonyms: 18:1 PE; 1,2-Dioleoyl-sn-glycero-3-PE; 1,2-Dioleoyl-sn-glycero-3-Phosphoethanolamine; 1,2-DOPE. Grades: >98.0%(T). CAS No. 4004-5-1. Molecular formula: C41H78NO8P. Mole weight: 744.1. | |
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