BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Doravirine | Doravirine is a non-nucleoside reverse transcriptase inhibitor under development of Merck & Co. IC 50 value is 12 nM against the wild type, 21nM against K103N, 31 nM against Y181C, 33nM against K103N/Y181C mutant viruses in vitro. MK-1439 exhibited similar antiviral activities against 10 different HIV-1 subtype viruses. Phase III for the treatment of HIV-1 infections is on-going. Uses: Hiv-1 infections. Synonyms: MK-1439; MK 1439; MK1439; MK-1439-019;3-Chloro-5-((1-((4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl)-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl)oxy)benzonitrile. Grades: 98%. CAS No. 1338225-97-0. Molecular formula: C17H11ClF3N5O3. Mole weight: 425.75. |  |
| Dorsomorphin | Dorsomorphin is a potent and selective inhibitor of AMPK (AMP-activated protein kinase) (Ki = 109 nM), induced by AICAR and metformin. It also inhibits bone morphogenetic protein (BMP) receptors including BMPR-IA (ALK3) and BMPR-IB (ALK6). Dorsomorphin can induce myocardial differentiation in mouse embryonic stem cells (mESCs). Uses: Protein kinase inhibitors. Synonyms: 6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine; Compound C; AMPK Inhibitor, Compound C; BML-275. Grades: >98%. CAS No. 866405-64-3. Molecular formula: C24H25N5O. Mole weight: 399.49. | |
| Dorzolomide hydrochloride | Cas No. 130693-82-2. | |
| DOTA derivative | DOTA derivative is a benxyl derivative of the cyclic tosamide; can be nitrated directly; is more convenient to incorporate the nitro group after deprotection lithium aluminum hydride. Synonyms: DOTA derivative. Grades: >98%. CAS No. 153777-70-9. Molecular formula: C43H50N4O8S4. Mole weight: 879.14. | |
| DOTA-GA(tBu)4 | Synonyms: 5-(tert-Butoxy)-5-oxo-4-(4,7,10-tris(2-(tert-butoxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecan-1-yl)pentanoic acid. CAS No. 306776-79-4. Molecular formula: C35H64N4O10. Mole weight: 700.9. | |
| DOTA-NOC | DOTA-NOC is a potent chelating agent extensively used in radiopharmaceuticals for the targeted imaging and therapy of neuroendocrine tumors. By combining with diverse radiometals, such as lutetium-177 or yttrium-90, it generates therapeutic agents that specifically bind to neuroendocrine tumor cells. The DOTA-NOC derivatives have displayed remarkable specificity and affinity for somatostatin receptors, endowing it with a unique potential for cancer therapy. Its diverse applications stem from its impressive properties, which include high burstiness in sentence structure and an elevated level of perplexity in its descriptions. Synonyms: DOTA-[Nal3]-octreotide; L-Cysteinamide, N-[[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-D-phenylalanyl-L-cysteinyl-3-(1-naphthalenyl)-L-alanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-. Grades: 95%. CAS No. 619300-53-7. Molecular formula: C69H94N14O17S2. Mole weight: 1455.7. | |
| DOTA-tris(tert-butyl ester) | Synonyms: Tri-tert-butyl 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetate; 2-(4,7,10-Tris(2-(tert-butoxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecan-1-yl)acetic acid; DOTA(OtBu) hydrobromide salt. Grades: 95%. CAS No. 137076-54-1. Molecular formula: C28H52N4O8. Mole weight: 572.7. | |
| DOTA-[Tyr3]-Octreotide Acid | DOTA-TATE, DOTATATE or DOTA-octreotate is a substance which, when bound to various radionuclides, has been tested for the treatment and diagnosis of certain types of cancer, mainly neuroendocrine tumours. Synonyms: DOTATATE; DOTA-(Tyr3,Thr8)-Octreotide; DOTA-[Tyr3] Octreotide Acid (Octreotate); 4,7,10-Tricarboxymethyl-1,4,7,10-tetraaza-cyclododecan-1-yl-acetyl-D-Phe-Cys-Tyr-D-Trp-Lys-Thr-Cys-Thr-OH acetate salt (Disulfide bond). Grades: 98%. CAS No. 177943-89-4. Molecular formula: C65H90N14O19S2. Mole weight: 1435.63. | |
| DOTMA | DOTMA is one of the first cationic lipid used for gene transfection. DOTMA carries a positive charge on the surface of liposomes which condenses anionic nucleic acids and promotes efficient interactions between the cell membrane and the liposome. Synonyms: 1,2-Di-O-Octadecenyl-3-Trimethylammonium Propane; Trimethyl[2,3-(dioleyloxy)propyl]ammonium Chloride; N-(1-(2,3-dioleyloxy)propyl)-N,N,N-trimethylammonium. Grades: >98%. CAS No. 104872-42-6. Molecular formula: C42H84ClNO2. Mole weight: 670.57. | |
| Dotriacontane | Dotriacontane is a long-chain alkane. Synonyms: n-Dotriacontane. CAS No. 544-85-4. Molecular formula: C32H66. Mole weight: 450.87. | |
| Doxepin Hydrochloride | Highly potent H1 histamine receptor antagonist (Kd = 310 pM) and tricyclic antidepressant. Also binds to the H4 histamine receptor (pKi = 6.79). Synonyms: Sinequan; Adapin; Silenor. Grades: >98%. CAS No. 1229-29-4. Molecular formula: C19H22ClNO. Mole weight: 315.84. | |
| Doxofylline Impurity 1 | Doxofylline Impurity 1 is a Doxofylline impurity. Doxofylline is a phosphodiesterase inhibitor and a xanthine derivative drug for asthma. Synonyms: 1-(1,3-Dioxolan-2-ylmethyl)-N-methyl-4-(methylamino)-1H-imidazole-5-carboxamide. Grades: > 95%. CAS No. 1429636-74-7. Molecular formula: C10H16N4O3. Mole weight: 240.26. | |
| Doxofylline Impurity 2 | Doxofylline Impurity 2 (Theophylline Impurity 2) is a Doxofylline impurity. Doxofylline is a phosphodiesterase inhibitor and a xanthine derivative drug for asthma. Synonyms: Theophylline Impurity 1; 1,2,3,6-Tetrahydro-1,3-dimethyl-2,6-dioxopurine-7-acetaldehyde; 7-(Formylmethyl)theophylline; 7-Theophyllineacetaldehyde. Grades: > 95%. CAS No. 5614-53-9. Molecular formula: C9H10N4O3. Mole weight: 222.20. | |
| Doxycycline Hyclate | Doxycycline is a member of the tetracycline antibiotics group, and is commonly used to treat a variety of infections. Synonyms: (4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide Hyclate; Doxinyl; Doxivetin; Doxycen; GS 3065; Hydramycin; Liviatin; Doxycycline Hydrochloride Hemiethanolate Hemihydrate. Grades: Assay?800 - 920 μg/mg. CAS No. 24390-14-5. Molecular formula: C23H29ClN2O9. Mole weight: 512.94. | |
| D-Pantothenic Acid Sodium Salt | D-Pantothenic acid sodium is a sodium salt form of the biologically active enantiomer of pantothenic acid, which is a precursor in the biosynthesis of coenzyme A. It is a water-soluble vitamin and an essential nutrient for for many animals. It is used to synthesize coenzyme-A (CoA) and synthesize and metabolize proteins, carbohydrates, and fats by animals. Uses: D-pantothenic acid sodium is an essential nutrient for for many animals. it is used to synthesize coenzyme-a (coa) and synthesize and metabolize proteins, carbohydrates, and fats by animals. Synonyms: Sodium D-pantothenate;N-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-,monosodiumsalt,(R)-.beta.-Alanine;Sodium pantothenate;Vitamin B5 sodium;Sodium (R)-3-(2,4-dihydroxy-3,3-dimethylbutanamido)propanoate. Grades: 99%. CAS No. 867-81-2. Molecular formula: C9H16NNaO5. Mole weight: 241.22. | |
| DPC-681 | DPC-681, sulfonamide derivatives, is an extremely potent and selective inhibitor of HIV protease. IC90s: wild-type HIV-1=4-40 nM. Synonyms: DPC 681; DPC-681; DPC681; DPH 153893; DPH-153893; DPH153893; (2R)-N-(2-aminoacetyl)-2-[[(2S)-4-[(3-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]-[(3-fluorophenyl)methyl]amino]-3,3-dimethylbutanamide284661-68-3AM021737N-((3-Fluorophenyl)methyl)glycyl-N-((1S,2R)-3-(((3-aminophenyl)sulfo. Grades: 99.89%. CAS No. 284661-68-3. Molecular formula: C35H48FN5O5S. Mole weight: 669.857. | |
| DPC-AJ1951 trifluoroacetate salt | DPC-AJ1951 is a potent 14 amino acid peptide agonist of the parathyroid hormone (PTH)/PTH-related peptide receptor (PPR). It induces cAMP production in SAOS-2 and UMR106 cells that endogenously express human and rat PPR, respectively (EC50s = 2.2 and 1.1 nM, respectively). Synonyms: 2-methylalanyl-L-valyl-2-methylalanyl-L-α-glutamyl-L-isoleucyl-L-glutaminyl-L-leucyl-L-norleucyl-L-histidyl-L-glutaminyl-L-arginyl-L-alanyl-L-lysyl-L-tyrosinamide, trifluoroacetate salt. Grades: ≥95%. CAS No. 943519-33-3. Molecular formula: C76H127N23O19·xCF3COOH. Mole weight: 1667. | |
| DPO-1 | DPO-1, a blocker of IKur ultrarapid delayed rectifier potassium current and KV1.5 channels, has been found to exhibit activities in preventing atrial arrhythmia. Synonyms: [1S- (1α , 2α , 5β ) ]-[5-Methyl-2- (1-methylethyl) cyclohexyl]diphenylphosphine oxide. Grades: ≥99% by HPLC. CAS No. 43077-30-1. Molecular formula: C22H29OP. Mole weight: 340.44. | |
| (D)-PPA 1 | PD-1/PD-L1 interaction inhibitor. Binds to PD-L1 (Kd = 0.51 μM). Inhibits interaction at 1 mg/mL in flow cytometry. Inhibits tumor growth and prolongs survival time of mice in vivo. Synonyms: H-D-Asn-D-Tyr-D-Ser-D-Lys-D-Pro-D-Thr-D-Asp-D-Arg-D-Gln-D-Tyr-D-His-D-Phe-OH. Grades: ≥95%. CAS No. 1620813-53-7. Molecular formula: C70H98N20O21. Mole weight: 1555.67. | |
| DPPC | DPPC (1,2-Dipalmitoyl-sn-glycero-3-phosphocholine) is a kind of glycerol phosphate, which has been used to prepare liposome monolayer/bilayer. It is used as a lung surfactant and diagnostic aid (fetal lung maturity). Synonyms: 1,2-Dipalmitoyl-sn-glycero-3-Phosphatidylcholine; L-Dipalmitoyl Lecithin. Grades: >98.0% by HPLC. CAS No. 63-89-8. Molecular formula: C40H80NO8P. Mole weight: 734.05. | |
| DPPE | DPPE (1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine), a glycerophosphonoethanolamine family member, is used in the model membrane. Synonyms: 16:0 PE; 1,2-Dipalmitoyl-sn-glycero-3-PE; 1,2-Dipalmitoyl-sn-glycerol-3-Phosphoethanolamine; 1,2-DPPE. Grades: ≥98%. CAS No. 923-61-5. Molecular formula: C37H74NO8P. Mole weight: 691.96. | |
| DPPE fumarate | The fumarate salt form of DPPE, which has been found to show high affinity binding to the antiestrogen binding site and induce sterol accumulation in MCF7 cells. Synonyms: N,N-Diethyl-2-[4-(phenylmethyl)phenoxy]ethanamine fumarate. Grades: ≥95% by HPLC. CAS No. 1185241-83-1. Molecular formula: C19H25NO.C4H4O4. Mole weight: 399.49. | |
| DPPE-mPEG | DPPE-mPEG is a phospholipid containing a polyether unit. It can be used for PEG-biochemical conjugation, and be utilized in micelles, liposomes, and other lipid-based drug carriers. Synonyms: N-(Carbamoyl-methoxypolyethylene glycol)-1,2-dipalmitoyl-cephalin; N-(Carbonyl-methoxypolyethylenglycol)-1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine, Carbonyl-methoxypolyethylenglycol labeled; Poly(oxy-1,2-ethanediyl), α-[(9R)-6-hydroxy-6-oxido-1,12-dioxo-9-[(1-oxohexadecyl)oxy]-5,7,11-trioxa-2-aza-6-phosphaheptacos-1-yl]-ω-methoxy-. Grades: >95%. CAS No. 205494-72-0. Molecular formula: (C2H4O)nC39H76NO10P. Mole weight: 794.0. | |
| DprE1-IN2 | DprE1-IN-2 is a potent DprE1 inhibitor with an IC50 of 28 nM. And it has antituberculosis effect. Synonyms: 1-[[6-(dimethylamino)-5-methyl-4-pyrimidinyl]methyl]-N-(2-hydroxyethyl)-6-methyl-1H-pyrrolo[3,2-b]pyridine-3-carboxamide. Grades: ≥98%. CAS No. 1615713-87-5. Molecular formula: C19H24N6O2. Mole weight: 368.4. | |
| DPY-2103 | DPY-2103 is a useful intermediate for chemical synthesis of a number of biologically active drugs. Uses: A useful intermediate. Synonyms: DPY-2103; DPY 2103; DPY2103; dimethyl 3,3'-(methylenebis(5-formyl-4-methyl-1H-pyrrole-2,3-diyl))dipropionate. Grades: ≥98%. CAS No. 4792-10-3. Molecular formula: C21H26N2O6. Mole weight: 402.45. | |
| DPY-3050 | DPY-3050 is a useful intermediate for chemical synthesis of a number of biologically active drugs. Uses: A useful intermediate. Synonyms: DPY-3050; DPY 3050; DPY3050. 1H-Pyrrole-3-propanoic acid, 2,?2'-methylenebis[5-[(1,?1-dimethylethoxy)?carbonyl]?-4-methyl-, 3,?3'-dimethyl ester. Grades: ≥96%. CAS No. 30103-05-0. Molecular formula: C29H42N2O8. Mole weight: 546.29. | |
| DPY-6602 | DPY-6602, a pyrrole derivative, could be widely used as an intermediate in sorts of areas like photosensitizers and antitumor drugs. Synonyms: DPY-6602; DPY 6602; DPY6602; tert-butyl 5-((4-ethyl-5-formyl-3-methyl-1H-pyrrol-2-yl)methyl)-3,4-dimethyl-1H-pyrrole-2-carboxylate. Grades: 98%. CAS No. 145696-60-2. Molecular formula: C20H28N2O3. Mole weight: 344.21. | |
| DREADD agonist 21 | DREADD agonist 21 has been found to be an agonist of hM3Dq with high selectivity. Synonyms: DREADD agonist 21; DREADD-agonist-21; DREADD agonist-21; 11-(1-Piperazinyl)-5H-dibenzo[b,e][1,4]diazepine. Grades: ≥98% by HPLC. CAS No. 56296-18-5. Molecular formula: C17H18N4. Mole weight: 278.35. | |
| DREADD agonist 21 dihydrochloride | DREADD agonist 21 (Compound 21) hydrochloride is a water soluble salt of DREADD agonist 21 (Compound 21). And it is a potent and selective agonist at muscarinic based DREADDs such as the excitatory hM3Dq, hM1Dq and inhibitory hM4Di DREADDs. Synonyms: 11-(1-Piperazinyl)-5H-dibenzo[b,e][1,4]diazepine dihydrochloride; 11-(Piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine; 11-Piperazinyldibenzo[b, e][1, 4]diazepine dihydrochloride; Compound 21 dihydrochloride. Grades: ≥98% by HPLC. Molecular formula: C17H18N4·2HCl. Mole weight: 351.27. | |
| Dronedarone | Dronedarone is a Class III antiarrhythmic and a multi-channel blocker for atrial fibrillation. It blocks potassium, sodium, and calcium channels and also exhibits antiadrenergic properties. Uses: Antiarrhythmic. Synonyms: Multaq; SR-33589; SR33589; SR 33589; SR-33589B. Grades: >98%. CAS No. 141626-36-0. Molecular formula: C31H44N2O5S. Mole weight: 556.76. | |
| Dronedarone HCl | Cas No. 141625-93-6. | |
| Droxicainide hydrochloride | The hydrochloride salt form of Droxicainide, a piperidine derivative, has been found to be an potential antiarrhythmic agent. Synonyms: Droxicainide hydrochloride;AL-S 1249; Droxicainide HCl; S 1249; S-1249; UNII-91801A0812. (+-)-N-(2-Hydroxyethyl)pipecolinyl-2,6-dimethylanilide hydrochloride; S-1249; (+-)-N-(2,6-Dimethylphenyl)-1-(2-hydroxyethyl)-2-piperidinecarboxamide monohydrochloride; 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-(2-hydroxyethyl)-, monohydrochloride. Grades: 98%. CAS No. 149572-05-4. Molecular formula: C16H25ClN2O2. Mole weight: 312.84. | |
| DS-1040 Tosylate | DS-1040 inhibits the activated form of thrombin-activatable fibrinolysis inhibitor (TAFIa), used for the treatment of acute ischemic stroke (AIS). DS-1040 substantially decreased TAFIa activity but had no impact on bleeding time. DS-1040 may provide an option of safer thrombolytic therapy. Synonyms: DS-1040 Tosylate; DS 1040 Tosylate; DS1040 Tosylate; (2S)-5-amino-2-[[1-(4-methylcyclohexyl)imidazol-4-yl]methyl]pentanoic acid;4-methylbenzenesulfonic acid; DS-1040 (Tosylate). CAS No. 1335138-89-0. Molecular formula: C23H35N3O5S. Mole weight: 465.61. | |
| DSLET | DSLET is a selective δ opioid receptor agonist peptide with analgesic effects. Uses: Analgesics. Synonyms: (D-Ser2)-Leu-Enkephalin-Thr; 2-Ser-thr-leu-enkephalin; H-Tyr-D-Ser-Gly-Phe-Leu-Thr-OH; YsGFLT; L-tyrosyl-D-seryl-glycyl-L-phenylalanyl-L-leucyl-L-threonine; L-Threonine, L-tyrosyl-D-serylglycyl-L-phenylalanyl-L-leucyl-; L-Threonine, N-[N-[N-[N-(N-L-tyrosyl-D-seryl)glycyl]-L-phenylalanyl]-L-leucyl]-; L-Tyrosyl-D-serylglycyl-L-phenylalanyl-L-leucyl-L-threonine; [D-Ser2-Leu5-Thr6]enkephalin; [D-Ser2-Leu5]enkephalin-Thr6; H-Tyr-D-Ser-Gly-Phe-Leu-Thr; Tyr-D-Ser-Gly-Phe-Leu-Thr-OH; Dislet; DSTLE. Grades: 98%. CAS No. 75644-90-5. Molecular formula: C33H46N6O10. Mole weight: 686.75. | |
| dSpacer-CEP | dSpacer is used to introduce stable abasic sites in oligonucleotides. Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-1',2'-dideoxyribose-3'-O-[(2-cyanoethyl)-(N,N-Diisopropyl)]-phosphoramidite; 1',2'-Dideoxy-5'-O-DMT-ribose 3'-CE phosphoramidite; dSpacer CE Phosphoramidite; (2R, 3S) -2- ( (Bis (4-methoxyphenyl) (phenyl) methoxy) methyl) tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; D-erythro-Pentitol, 1,4-anhydro-5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-, 3-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]. Grades: ≥95%. CAS No. 129821-76-7. Molecular formula: C35H45N2O6P. Mole weight: 620.71. | |
| DSPC | DSPC (1,2-Distearoyl-sn-glycero-3-phosphocholine) is a phosphatidylcholine, which is a phospholipid. It is a natural component of cell membranes and can be used to prepare lipid nanoparticles for mRNA vaccines. It forms part of the delivery system of Moderna and Pfizer COVID-19 vaccines. DSPC is used to produce non-pyrogenic liposomes capable of caging molecules. Synonyms: 18:0 PC; Distearoylphosphatidylcholine; 1,2-Bis(stearoyl)-sn-g1,2-Bis(stearoyl)-sn-glycero-3-phosphocholinelycero-3-phosphocholine. Grades: 98%. CAS No. 816-94-4. Molecular formula: C44H88NO8P. Mole weight: 790.1. | |
| DSPE | DSPE (1,2-Distearoyl-sn-glycero-3-phosphoethanolamine) is a water-soluble derivative of phosphatidylethanolamine with (18:0) stearic acid acyl chains. BOC Sciences provides high-quality DSPE ?for your projects. Synonyms: 18:0 PE; 1,2-Distearoyl-sn-Glycero-3-Phosphatidylethanolamine; 1,2-Distearoyl-sn-glycero-3-PE; Distearoylphosphatidylethanolamine; 1,2-dioctadecyl-rac-glycero-3-phosphoethanolamine. Grades: >98%. CAS No. 1069-79-0. Molecular formula: C41H82NO8P. Mole weight: 748.07. | |
| DSPE-mPEG | DSPE-mPEG is a phospholipid containing a polyether unit. It can be used for PEG-biochemical conjugation, and be utilized in micelles, liposomes, and other lipid-based drug carriers. It is used to study the stability, biodistribution and toxicity of lung-specific liposome anti-tuberculosis drugs. Synonyms: Poly(oxy-1,2-ethanediyl), α-[6-hydroxy-6-oxido-1,12-dioxo-9-[(1-oxooctadecyl)oxy]-5,7,11-trioxa-2-aza-6-phosphanonacos-1-yl]-ω-methoxy-; 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethyleneglycol)]; N-(Carbonyl-methoxypolyethylenglycol)-1,2-distearoyl-sn-glycero-3-phosphoethanolamine; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine, Carbonyl-methoxypolyethylenglycol labeled; N-(Carbamoyl-methoxy peg)-1,2-distearoyl-cephalin; Poly(oxy-1,2-ethanediyl), alpha-((9R)-6-hydroxy-6-oxido-1,12-dioxo-9-((1-oxooctadecyl)oxy)-5,7,11-trioxa-2-aza-6-phosphanonacos-1-yl)-omega-methoxy-; α-[6-Hydroxy-6-oxido-1,12-dioxo-9-[(1-oxooctadecyl)oxy]-5,7,11-trioxa-2-aza-6-phosphanonacos-1-yl]-ω-methoxy-Poly(oxy-1,2-ethanediyl). Grades: >99% by HPLC. CAS No. 147867-65-0. Molecular formula: (C2H4O)nC43H84NO10P. Mole weight: 872.1. | |
| DSPE-mPEG-1000 | DSPE-mPEG-1000 is suitable for fabricating non-supported sensor like quartz crystal microbalance (QCM) odor sensors and in the preparation of holmium nanoparticles. Synonyms: 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)1000] ammonium salt; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)] ammonium salt; DSPE-mPEG; DSPE-PEG 1000; DSPE-PEG-methoxy 1000; LPEG 1000; MPEG-DSPE. Grades: >99%. CAS No. 474922-77-5. Molecular formula: (C2H4O)nC43H84NO10P.NH3. Mole weight: 5801.14. | |
| DSPE-PEG (2000) Amine | Cas No. 474922-26-4. | |
| DSR 6434 | DSR 6434 is a potent TLR7 agonist (EC50 = 7.2 nM). Synonyms: DSR 6434; DSR6434; DSR-6434; CHEMBL2315158; SCHEMBL1146577; SCHEMBL13448863; BDBM50425234; AKOS025147319; 1059070-10-8; 6-Amino-2-(butylamino)-9-[[6-[2-(dimethylamino)ethoxy]-3-pyridinyl]methyl]-7,9-dihydro-8H-purin-8-one. CAS No. 1059070-10-8. Molecular formula: C19H28N8O2. Mole weight: 400.48. | |
| D-Theanine | D-Theanine, a prominent amino acid derivative abundant in tea leaves, is renowned for its calming properties that can unwind the mind and body. As a dietary supplement, it is typically used to mitigate stress and anxiety, fostering a sense of relaxation. Research has also indicated its capacity to enhance cognitive functions and alleviate depressive symptoms, suggesting that it holds potential as a multipurpose supplement. Synonyms: H-D-Gln(Et)-OH. CAS No. 5822-62-8. Molecular formula: C7H14N2O3. Mole weight: 174.20. | |
| DTHIB | DTHIB is a direct and selective heat shock factor 1 (HSF1) inhibitor with a Kd of 160 nM. DTHIB strongly inhibits HSF1 cancer gene signature and prostate cancer cell proliferation. Synonyms: Urea, N-(4-chloro-3-nitrophenyl)-N'-(4-fluorophenyl)-. Grades: 98%. CAS No. 897326-30-6. Molecular formula: C13H9ClFN3O3. Mole weight: 309.68. | |
| DTP3 | DTP3 is a selective GADD45β/MKK7 inhibitor, which interacts with and caused a significant conformational change of GADD45β/MKK7 complex in a dose dependent way, as well as of the isolated MKK7 protein. Synonyms: (2R)-2-[[(2R)-2-acetamido-3-(4-hydroxyphenyl)propanoyl]amino]-N-[(2R)-1-amino-1-oxo-3-phenylpropan-2-yl]-5-(diaminomethylideneamino)pentanamide. Grades: ≥98%. CAS No. 1809784-29-9. Molecular formula: C26H35N7O5. Mole weight: 525.6. | |
| Dulcoside A | Dulcoside A is a natural compound which can be isolated from Stevia rebaudiana. Synonyms: Dulcoside A; 64432-06-0; UNII-BV1X94PJ0P; BV1X94PJ0P; CCRIS 6117; DULCOSIDEA; (-)-DULCOSIDE A; DULCOSIDE A, (-)-; [(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (1R, 4S, 5R, 9S, 10R, 13S)-13-[(2S, 3R, 4S, 5S, 6R)-4, 5-dihydroxy-6-(hydroxymethyl)-3-[(2S, 3R, 4R, 5R, 6S)-3, 4, 5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5, 9-dimethyl-14-methylidenetetracyclo[11.2.1.01, 10.04, 9]hexadecane-5-carboxylate; DUL; DTXSID40983005; CHEBI:186967; HY-N6992; AKOS040760372; 1ST40346; MS-31448; CS-0086402; Q27274899; KAUR-16-EN-18-OIC ACID, 13-((2-O-(6-DEOXY-.ALPHA.-L-MANNOPYRANOSYL)-.BETA.-D-GLUCOPYRANOSYL)OXY)-. BETA.-D-GLUCOPYRANOSYL ESTER, (4.ALPHA.)-; KAUR-16-EN-18-OIC ACID, 13-((2-O-(6-DEOXY-alpha-L-MANNOPYRANOSYL)-beta-D-GLUCOPYRANOSYL)OXY)-, beta-D-GLUCOPYRANOSYL ESTER, (4alpha)-. Grades: 98%. CAS No. 64432-06-0. Molecular formula: C38H60O17. Mole weight: 788.87. | |
| Duloxetine | Duloxetine is a serotonin-norepinephrine reuptake inhibitor (Ki=4.6 nM), used for major depressive disorder, generalized anxiety disorder, fibromyalgia and neuropathic pain. Uses: Adrenergic uptake inhibitors; analgesics; antidepressive agents; dopamine uptake inhibitors; serotonin uptake inhibitors. Synonyms: (S)-Duloxetine; Cymbalta; Yentreve; (S)-N-Methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine; LY 248686; Xeristar; LY248686; LY-248686; (γS)-N-Methyl-γ-(1-naphthalenyloxy)-2-thiophenepropanamine; (+)-(S)-N-Methyl-γ-(1-naphthyloxy)-2-thiophenepropylamine; (3S)-N-Methyl-3-(1-naphthyloxy)-3-(2-thienyl)-1-propanamine. Grades: >98%. CAS No. 116539-59-4. Molecular formula: C18H19NOS. Mole weight: 297.41. | |
| D-Val-Leu-Lys 4-nitroanilide dihydrochloride | D-Val-Leu-Lys 4-nitroanilide dihydrochloride stands as a crucial substrate to gauge the efficiency of trypsin-like serine proteases. Proteolysis event leads to the release of a yellow colored product, whose quantification can be done at 405 nm. Its utility can be seen in trypsin activity detection and the evaluation of agents restricting trypsin-like proteases. Consistent usage of this product aids in experimental design and the analysis of diverse protease substrates. Synonyms: (S)-6-Amino-2-((S)-2-((R)-2-amino-3-methylbutanamido)-4-methylpentanamido)-N-(4-nitrophenyl)hexanamide dihydrochloride; H-D-Val-Leu-Lys-pNA 2HCl. CAS No. 62354-43-2. Molecular formula: C23H40Cl2N6O5. Mole weight: 551.5. | |
| D-xylo-Hexos-4-ulose | D-xylo-Hexos-4-ulose is a carbohydrate compound, purposefully employed in the ever-expanding ambit of diabetes research. Synonyms: (2R,3R,5R)-2,3,5,6-tetrahydroxy-4-oxohexanal. CAS No. 55908-15-1. Molecular formula: C6H10O6. Mole weight: 178.14. | |
| D-Xylulose 5-phosphate sodium salt | D-Xylulose 5-phosphate is a metabolite of glucose via the pentose phosphate pathway. Synonyms: 5-(Dihydrogen phosphate)-D-threo-2-pentulose sodium salt. CAS No. 138482-70-9. Molecular formula: C5H11O8P.xNa. Mole weight: 230.11 (free acid). | |
| Dynarrestin | Dynarrestin is a potent and selective reversible inhibitor of dynein 1 and 2. Dynarrestin exhibits reversible inhibition of cytoplasmic dynein 1-dependent microtubule binding and cytoplasmic dynein 2-dependent intraflagellar transport. Synonyms: Ethyl 4-(4-(diethylamino)phenyl)-2-((2,4-difluorophenyl)amino)thiazole-5-carboxylate; 4-(4-Diethylaminophenyl)-2-(2,4-difluoro-phenylamino)-thiazole-5-carboxylic acid ethyl ester. Grades: ≥98% by HPLC. CAS No. 2222768-84-3. Molecular formula: C22H23F2N3O2S. Mole weight: 431.5. | |
| Dynorphin A (1-13) | Dynorphin A is an endogenous opioid peptide that preferentially activates κ opioid receptors. Synonyms: Dynorphin A Porcine Fragment 1-13; Porcine dynorphin A(1-13); H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-OH; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-prolyl-L-lysyl-L-leucyl-L-lysine; 1-13-Dynorphin A (swine). Grades: 98%. CAS No. 72957-38-1. Molecular formula: C75H126N24O15. Mole weight: 1603.95. | |
| Dynorphin A (1-8) | Dynorphin A (1-8) is an opioid octapeptide that exhibits agonist activity at μ and δ receptors. Synonyms: Dynorphin A fragment 1-8 porcine; H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-OH. Grades: 98%. CAS No. 75790-53-3. Molecular formula: C46H72N14O10. Mole weight: 981.15. | |
| DZ2002 | DZ2002 is a potent and reversible S-Adenosyl-L-homocysteine Hydrolase(SAHH; AdoHcy Hydrolase) inhibitor with Ki of 17.9 nM. Synonyms: DZ-2002; DZ 2002; DZ2002. Grades: >98%. CAS No. 33231-14-0. Molecular formula: C10H13N5O3. Mole weight: 251.24. | |
| (E)-2-Decenoic acid | trans-2-Decenoic Acid is isolated along with 10-hydroxy-trans-2-decenoic acid, a fatty acid unique to royal jelly.(E)-2-decanoic acid(trans-2-Decenoic Acid) and 10-hydroxy-trans-2-decenoic acid are both described to demonstrate estrogenic activity, where the fatty acids demonstrate inhibition of 17β-estradiol binding to estrogen receptor-&beta. Synonyms: trans-2-Decenoic acid. Grades: >98%. CAS No. 334-49-6. Molecular formula: C10H18O2. Mole weight: 170.25. | |
| E-64 | E-64 is an irreversible and selective cysteine protease inhibitor with IC50 of 9 nM for papain. Uses: For research used only. Synonyms: L-trans-Epoxysuccinyl-Leu-4-guanidinobutylamide; Proteinase inhibitor E 64; 3-[[[ (1S) -1-[[[4-[ (aminoiminomethyl) amino]butyl]amino]carbonyl]-3-methylbutyl]amino]carbonyl]- (2S, 3S) -oxiranecarboxylic acid; Thiol protease inhibitor; trans-Epoxysuccinyl-L-leucylamido-(4-guanidino)butane; 2-Oxiranecarboxylic acid, 3-[[[ (1S) -1-[[[4-[ (aminoiminomethyl) amino]butyl]amino]carbonyl]-3-methylbutyl]amino]carbonyl]-, (2S,3S)-; L-Trans-Epoxysuccinyl-Leu-agmatine. Grades: ≥99% by HPLC. CAS No. 66701-25-5. Molecular formula: C15H27N5O5. Mole weight: 357.41. | |
| E6 Berbamine | E6 Berbamine is a calmodulin inhibitor, which is also reported to inhibit P-glycoprotein activity in purified primary cultured rat brain microvessel endothelial cells at 10 μM. Calmodulin is the ubiquitous and multifunctional Ca2+-binding protein, which can mediate various regulatory effects of Ca2+. Synonyms: Berbamine p-nitrobenzoate; O-(4-Nitrobenzoyl)berbamine. Grades: ≥98%. CAS No. 114784-59-7. Molecular formula: C44H43N3O9. Mole weight: 757.8. | |
| (E)-8-Dodecen-1-yl acetate | (E)-8-Dodecen-1-yl acetate, a significant and highly functional organic compound, is commonly employed within the biomedical sector, featuring prominently as both a flavoring agent and synthetic ingredient within various cosmetic, soap, and perfume formulations. Capitalizing on its propensity to deter or attract diverse insect species, the compound has also emerged as a possible remedy for insect prevention and control in the agricultural domain, exhibiting encouraging outcomes. Synonyms: 8E-Dodecenyl acetate; (E)-8-Dodecen-1-ol acetate; (E)-8-Dodecenyl acetate; 8-Dodecen-1-ol, acetate, (E)-; trans-8-dodecenyl acetate; (8E)-8-Dodecenyl acetate; Trans-8-Dodecen-1-yl Acetate. Grades: 98%. CAS No. 38363-29-0. Molecular formula: C14H26O2. Mole weight: 226.36. | |
| (E)-8-Methyl-6-nonenoic acid | (E)-8-Methyl-6-nonenoic acid is a thermal degradant of Capsaicin. Synonyms: 8-methylnonenoate; 8-Methyl-6-nonenoic acid; (E)-8-methylnon-6-enoic acid. Grades: >95%. CAS No. 59320-77-3. Molecular formula: C10H18O2. Mole weight: 170.25. | |
| E-982 | E-982 is a potent and selective inhibitor designed for the research of prostate cancer. This product exhibits high binding specificity to the androgen receptor, preventing its activation and subsequent tumor growth. Synonyms: E982; E 982; E-982. Grades: >98 %. CAS No. 858102-78-0. Molecular formula: C25H31NO6S. Mole weight: 473.58. | |
| EBE-A22 | The brominated anilinoquinazoline derivative PD153035 exhibits a very high affinity and selectivity for the epidermal growth factor receptor tyrosine kinase (EGF-R TK) and shows a remarkable cytotoxicity against several types of tumor cell lines. Uses: Intercalating agents. Synonyms: EBE-A22; EBE A22; EBEA22. Grades: >98%. CAS No. 229476-53-3. Molecular formula: C17H16BrN3O2. Mole weight: 374.23. | |
| Ebeiedinone | Ebeiedinone is a cutting-edge natural compound used in the research of multiple diseases, including cancer and infectious diseases. Synonyms: Ebwardine. Grades: >98%. CAS No. 25650-68-4. Molecular formula: C27H43NO2. Mole weight: 413.646. | |
| Eberconazole Nitrate | Eberconazole is an antifungal drug commonly used as topical creams for the treatment of skin infections. CAS No. 130104-32-4. Molecular formula: C18H14Cl2N2.HNO3. Mole weight: 392.24. | |
| EBI-907 | EBI-907, an isoquinolin derivative, has been found to be a B-RafV600E inhibitor and exhibit activities against some oncogenic kinases at some extent. The researches of it against breast cancer is still in progress. Synonyms: EBI-907; EBI 907; EBI907; N-(2-chloro-3-(1-cyclopropyl-8-methoxy-3H-pyrazolo[3,4-c]isoquinolin-7-yl)-4-fluorophenyl)-3-fluoropropane-1-sulfonamide. Grades: 98%. CAS No. 1581764-31-9. Molecular formula: C23H21ClF2N4O3S. Mole weight: 506.95. | |
| Ecadotril | Ecadotril is a neutral endopeptidase(NEP) inhibitor and determined by the presence of peptidase family M13 as a neutral endopeptidase inhibited by phosphoramidon. lt is the (S)-enantiomer of racecadotril. It acts as an antihypertensive. Uses: Ecadotril acts as an antihypertensive. Synonyms: Ecadotril; BAY y 7432; BAY-y 7432; BP 1.02; S049; S.049; Sinorphan; N-[(S)-2-[(Acetylthio)methyl]-1-oxo-3-phenylpropyl]glycine benzyl ester;S-Acetorphan;Sinorphan;Benzyl 2-[[(2S)-2-(acetylsulfanylmethyl)-3-phenylpropanoyl]amino]acetate; Glycine, N-(2-((acetylthio)methyl)-1-oxo-3-phenylpropyl)-, phenylmethyl ester, (S)-. Grades: 95%. CAS No. 112573-73-6. Molecular formula: C21H23NO4S. Mole weight: 385.48. | |
| Ecamsule.2Na | Ecamsule protect the skin from sunburn and erythema. It causes serious eye damage, so please wear protective gloves/protective clothing/eye protection/face protection. Uses: Sunscreening agents. Synonyms: Sodium ((1, 4-phenylenebis(methanylylidene))bis(7, 7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl-3-ylidene))dimethanesulfonate. Grades: ≥ 95.0%. CAS No. 90458-75-6. Molecular formula: C28H32Na2O8S2. Mole weight: 606.66. | |
| Ecteinascidin-Analog-1 | Ecteinascidin-Analog-1 is a useful intermediate for chemical sythesis of Ecteinascidin analogues. It is a family of tetrahydroisoquinoline alkaloids with wide range of antitumor and antimicrobial activities. Synonyms: tert-butyl (4R)-4-[(1R,3S)-3-(acetyloxymethyl)-7-methoxy-6-methyl-8-prop-2-enoxy-2-prop-2-enoxycarbonyl-3,4-dihydro-1H-isoquinolin-1-yl]-2,2-dimethyl-1,3-oxazolidine-3-carboxylate; AKOS030526959; CS-3406; HY-12395. Grades: >98%. CAS No. 874758-58-4. Molecular formula: C31H44N2O9. Mole weight: 588.69. | |
| Edaravone Impurity III | Edaravone Impurity. Synonyms: 2-(3-Methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-yl)-2-sulfopropanoic acid; 2-(3-methyl-5-oxo-1-phenyl-4H-pyrazol-4-yl)-2-sulfopropanoic acid; Edaravone Impurity III; Edaravone IMpurity P1; DTXSID80855974; BCP18301; AC-30014; B0060-462129; 2-(3-Methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-yl)-2-sulfopropanoicacid. Grades: > 95%. CAS No. 1357477-99-6. Molecular formula: C13H14N2O6S. Mole weight: 326.33. | |
| Edaravone impurity P3 | Edaravone Impurity. Synonyms: Edaravone Impurity VI. Grades: > 95%. CAS No. 1323485-71-7. Molecular formula: C13H16N2O4S. Mole weight: 296.35. | |
| Edaravone Impurity V | An impurity of Edaravone, a medication for the recovery from stroke. Synonyms: 4,4-Bis(1-phenyl-3-methyl-5-oxo-3-pyrazoline-4-yl)-1-phenyl-3-methyl-1H-pyrazole-5(4H)-one. Grades: >95%. CAS No. 124009-63-8. Molecular formula: C30H26N6O3. Mole weight: 518.577. | |
| Edivoxetine | This active molecular is a selective norepinephrine reuptake inhibitor that developed for ADHD (attention-deficit hyperactivity disorder) and as an antidepressant agent originated by Eli Lilly. In Jan 2014, Eli Lilly completed a phase III extension trial in adjunctive treatment of major depressive disorder in Japan. In Jul 2015, Eli Lilly terminates phase II/III trial in Attention deficit hyperactivity disorder. Synonyms: (αR,2S)-α-[(5-Fluoro-2-methoxyphenyl)methyl]-α-(tetrahydro-2H-pyran-4-yl)-2-morpholinemethanol; (1R)-2-(5-Fluoro-2-methoxyphenyl)-1-[(2S)-2-morpholinyl]-1-(tetrahydro-2H-pyran-4-yl)ethanol; 2-Morpholinemethanol, α-[(5-fluoro-2-methoxyphenyl)methyl]-α-(tetrahydro-2H-pyran-4-yl)-, (αR,2S)-; LY2216684; LY-2216684; LY 2216684. Grades: 95%. CAS No. 1194508-25-2. Molecular formula: C18H26FNO4. Mole weight: 339.41. | |
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