BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Ethyl 4-hydroxybutanoate | Cas No. 999-10-0. |  |
| Ethyl 5-bromothieno[3,2-b]thiophene-6-carboxylate | Ethyl 5-bromothieno[3,2-b]thiophene-6-carboxylate, an essential building block for medicinal chemistry, is employed as a key intermediate for synthesizing pharmaceuticals that address a wide spectrum of ailments including cancer, inflammation and bacterial infections. With its intrinsic value in drug discovery, this compound offers an unparalleled opportunity to design novel therapeutic agents with unexplored potential for mitigating a range of medical afflictions. As an indispensable tool in the field of drug development, Ethyl 5-bromothieno[3,2-b]thiophene-6-carboxylate is instrumental in enabling novel possibilities for treatment. Synonyms: Ethyl 2-bromothieno[3,2-b]thiophene-3-carboxylate. CAS No. 2055722-78-4. Molecular formula: C9H7BrO2S2. Mole weight: 291.2. | |
| Ethyl a-D-thioglucopyranoside | Ethyl α-D-thioglucopyranoside is a vital compound in biomedicine utilized for various purposes. It acts as a precursor in the synthesis of various drugs used in treating diabetes, cancer, and microbial infections. Moreover, it plays a crucial role in carbohydrate chemistry research, supporting the investigation of enzyme inhibitors and glycosylation reactions. Ethyl α-D-thioglucopyranoside's availability and versatility contribute to advancements in biomedicine, fostering drug development and pivotal studies on carbohydrate-based therapies. Synonyms: Ethyl a-thioglucopyranoside. CAS No. 13533-58-9. Molecular formula: C8H16O5S. Mole weight: 224.28. | |
| Ethyl arachidonate | Arachidonic acid (AA) is an unsaturated omega-6 fatty acid constituent of the phospholipids of cell membranes. Phospholipase A2 releases AA from the membrane phospholipids in response to inflammation. Uses: Arachidonic acid (aa) is an unsaturated omega-6 fatty acid constituent of the phospholipids of cell membranes. phospholipase a2 releases aa from the membrane phospholipids in response to inflammation. Synonyms: Arachidonic acid ethyl ester. Grades: 95%. CAS No. 1808-26-0. Molecular formula: C22H36O2. Mole weight: 332.52. | |
| Ethyl b-D-thioglucopyranoside | Ethyl b-D-thioglucopyranoside is a valuable chemical compound acting as an inhibitor for enzymes involved in carbohydrate metabolism. Additionally, it is employed in the synthesis of biologically active molecules, specifically designed to study diseases related to carbohydrate metabolism, such as diabetes and metabolic disorders. CAS No. 7473-36-1. Molecular formula: C8H16O5S. Mole weight: 224.28. | |
| Ethyl β-D-Glucuronide | Ethyl β-D-Glucuronide, a byproduct of ethanol metabolism, has been proposed as a promising biomarker for detecting excessive alcohol intake, both in the short- and long-term. Its clinical relevance lies in its utility as a diagnostic tool for drug and alcohol testing. The scientific community's ongoing efforts to establish reliable methods for measuring and interpreting Ethyl β-D-Glucuronide levels speak to its growing importance as a marker of alcohol consumption. Synonyms: Ethyl glucuronide;ethyl-beta-d-glucuronide; Ethyl beta-D-Glucuronide; Ethyl b-D-glucuronide; Ethyl ?-D-Glucuronide; ethyl beta-D-glucopyranosiduronic acid; ethylglucuronide; (2S,3S,4S,5R,6R)-6-ethoxy-3,4,5-trihydroxyoxane-2-carboxylic acid; (2S,3S,4S,5R,6R)-6-ethoxy-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid; beta-D-Glucopyranosiduronic acid, ethyl; D-Ethyl glucuronide.beta.-D-Glucopyranosiduronic acid, ethyl; Ethyl-beta-glucuronide; Ethylbeta-D-Glucuronide; beta-D-Ethyl glucuronide; Ethyl |A-D-Glucuronide; Ethyl beta -D-Glucuronide; Ethyl-beta-D-glucuronide, 100 mug/mL in methanol, ampule of 1 mL, certified reference material. CAS No. 17685-04-0. Molecular formula: C8H14O7. Mole weight: 222.19. | |
| Ethyl diethylcarbamate | Ethyl diethylcarbamate, a carbamate derivative, finds extensive use as an alcohol denaturant and as an intermediate for the production of pesticides and pharmaceuticals. Furthermore, it exhibits potential therapeutic effects as a cholinesterase inhibitor, offering respite in the management of myasthenia gravis, a neuromuscular disorder that is typified by muscle weakness and fatigue. Synonyms: Diethyl urethane; Diethylcarbamic acid ethyl ester; Carbamic acid, N,N-diethyl-, ethyl ester; NSC 24699; N,N-diethyl O-ethylcarbamate. CAS No. 3553-80-8. Molecular formula: C7H15NO2. Mole weight: 145.20. | |
| ethylsulfone | Ethylsulfone, a sulfone compound, finds its application in the pharmaceutical realm as an intermediate for the synthesis of different drugs, including anti-inflammatory and antihypertensive drugs. In addition, this versatile chemical functions as a stabilizer and solvent in electroplating solutions, and as a constituent in adhesive and coating formulations. Synonyms: ETHYL SULFONE; DIETHYL SULFONE; DIETHYL SULPHONE; (C2H5)2SO2; 1-(Ethylsulfonyl)ethane; 1,1'-sulfonylbis-Ethane. Grades: 98%. CAS No. 597-35-3. Molecular formula: C4H10O2S. Mole weight: 122.19. | |
| Ethynylestradiol Impurity E | An impurity of Estradiol. Estradiol? is the major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female genotype in embryogenesis and at puberty. Synonyms: 6-alpha-Hydroxy Ethynylestradiol. Grades: > 95%. CAS No. 27521-34-2. Molecular formula: C20H24O3. Mole weight: 312.41. | |
| Ethynylferrocene | Synonyms: Ethylnylferrocene. CAS No. 1271-47-2. Molecular formula: C12H10Fe. Mole weight: 210.05. | |
| Etidronic acid | Etidronic acid is widely used as a scale and corrosion inhibitor in industrial circulating cooling water systems of electric power, chemical industry, metallurgy, chemical fertilizer, and also in medium or low-pressure boilers, oilfield water injection, and oil pipeline. HEDP can also be used as a cleaning agent of metal and nonmetal in the textile industry, as a peroxide stabilizer and fixing agent in the bleaching and dyeing industry, as a complexing agent in the cyanide-free electroplating industry, as the carrier of radioactive elements in the pharmaceutical industry, and so on. Uses: Chelating agents. Synonyms: Phosphonic acid, P,P'-(1-hydroxyethylidene)bis-; P,P'-(1-Hydroxyethylidene)bis[phosphonic acid]; (1-Hydroxyethylidene)-1,1-bis(phosphonic acid); (1-Hydroxyethylidene)-1,1-diphosphonic acid; (1-Hydroxyethylidene)bisphosphonic acid; (1-Hydroxyethylidene)diphosphonic acid; 1-Hydroxy-1,1-diphosphonoethane; 1-Hydroxyethane-1,1-bisphosphonic acid; 1-Hydroxyethane-1,1-diphosphonic acid; 1-Hydroxyethane-1,1-diyldiphosphonic acid; 1-Hydroxyethane-1,2-diphosphonic acid; 1-Hydroxyethanediphosphonic acid; 1-Hydroxyethyl-1,1-diphosphoric acid; 1-Hydroxyethylidene-1,1-diphoshonic acid; 1-Hydroxyethylidene-1,1-diphosphoric acid; 1-Hydroxyethylidene-1,1'-diphosphonic acid; Acetodiphosphonic acid; Briquest ADPA-A; EHDP; Ethane-1-hydroxy-1,1-diphosphonic acid; Ethidronate; Ethydronate; Etidronate; H 501 (corrosion inhibitor); HDEPA; HEDP; Hydroxyethanediphosphonic acid; Ksidifon; NSC 227995; OEDF; OEDFK; OEDP; Oxyethylidenediphosphonic acid; Wayplex; Xidifon; Xidiphone; Xydiphone. Grades: ≥95%. CAS No. 2809-21-4. Molecular formula: C2H8O7P2. Mole weight: 206.02. | |
| Etimizol | Etimizol was shown to relieve amnesia effectively in the origin of which there is the hypoxic component (hypobaric hypoxia, actinomycin D, mechanical injury of the brain). lt has a catalytic effect on the respiratory center and belongs to the group of respiratory analeptics, however, it activates adrenokortikotropnuyu pituitary function, which leads to increased levels of glucocorticosteroids in the blood. Uses: Nootropic agents. Synonyms: Ethymisole; Antiffine; Ethylnorantiffeine. Grades: >98%. CAS No. 64-99-3. Molecular formula: C9H14N4O2. Mole weight: 210.23. | |
| Etiracetam | Etiracetam is an acetylcholine agonist used as a nootropic drug of the racetam family. S-enantiomer, Levetiracetam, is more active compared to the opposite R-enantiomer, UCB L-060. Uses: Nootropic drug. Synonyms: UCB 6474; UCB6474; UCB-6474; 2-(2-oxopyrrolidin-1-yl)butanamide. Grades: 98%. CAS No. 33996-58-6. Molecular formula: C8H14N2O2. Mole weight: 170.21. | |
| Etodolac Impurity L | An impurity of Etodolac. Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2. Synonyms: 3-(7-ethyl-3-(2-hydroxyethyl)-1H-indol-2-yl)pent-3-enoic acid. Grades: > 95%. Molecular formula: C17H21NO3. Mole weight: 287.36. | |
| Etomidate Acid | Etomidate Acid is a metabolite of Etomidate. Etomidate is a short-acting intravenous anaesthetic agent used for the induction of general anaesthesia and sedation for short procedures such as reduction of dislocated joints, tracheal intubation, and cardioversion. Synonyms: (R)-(+)-1-(1-Phenylethyl)-1H-imidazole-5-carboxylic acid; (R)-Desethyl-etomidate. Grades: 95%. CAS No. 56649-48-0. Molecular formula: C12H12N2O2. Mole weight: 216.24. | |
| Etomidate Impurity 1 | One impurity of Etomidate. Etomidate is a GABAA receptor agonist, used as a short-acting anaesthetic agent or sedative. Synonyms: 1-[(1R)-1-phenylethyl]-1H-Imidazole. Grades: 95%. CAS No. 844658-92-0. Molecular formula: C11H12N2. Mole weight: 172.23. | |
| Etoricoxib | Etoricoxib is a selective COX-2 inhibitor. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: 5-Chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]-2,3'-bipyridine; Algix; Arcoxia; Etobrix; Etocox; Etoxib; Etropain; Kingcox; MK 0663; MK 663; Tauxib; Torcoxia; Etoricoxib crystal form V. Grades: ≥ 99%. CAS No. 202409-33-4. Molecular formula: C18H15ClN2O2S. Mole weight: 358.84. | |
| Etoricoxib Impurity 10 | An impurity of Etoricoxib. Etoricoxib is a selective COX-2 inhibitor. Synonyms: 5-chloro-2-(6-methylpyridin-3-yl)-3-(4-methylsulfinylphenyl)pyridine. Grades: > 95%. CAS No. 316149-01-6. Molecular formula: C18H15ClN2OS. Mole weight: 342.85. | |
| Etoricoxib Impurity 7 | An impurity of Etoricoxib. Etoricoxib is a selective COX-2 inhibitor. Synonyms: N,N-dimethyl-6-(6-methylpyridin-3-yl)-5-(4-methylsulfonylphenyl)pyridin-3-amine. Grades: > 95%. CAS No. 646459-39-4. Molecular formula: C20H21N3O2S. Mole weight: 367.47. | |
| Etoricoxib N-Oxide | An impurity of Etoricoxib. Etoricoxib is a selective COX-2 inhibitor. Synonyms: 5-Chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]-2,3'-bipyridine 1'-Oxide. Grades: > 95%. CAS No. 325855-74-1. Molecular formula: C18H15ClN2O3S. Mole weight: 374.85. | |
| ETP 45835 dihydrochloride | ETP 45835 dihydrochloride is a Mnk2 and Mnk1 inhibitor (IC50 = 575 and 646 nM, respectively) displaying selectivity against a panel of 24 protein kinases, including those upstream of Mnk1/2. Synonyms: ETP 45835 dihydrochloride; ETP45835 dihydrochloride; ETP-45835 dihydrochloride; 4-[5-(4-Piperidinyl)-1H-pyrazol-3-yl]pyridine dihydrochloride. Grades: ≥99% by HPLC. CAS No. 2136571-30-5. Molecular formula: C13H16N4.2HCl. Mole weight: 301.21. | |
| Etravirine | Etravirine (ETR, brand name Intelence, formerly known as TMC125) is a drug used for the treatment of HIV. Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI). Etravirine works by reducing the amount of HIV and increasing the number of CD4 or T cells in the blood. Unlike the currently available agents in the class, resistance to other NNRTIs does not seem to confer resistance to etravirine. Uses: Reverse transcriptase inhibitors. Synonyms: R165335; R-165335; R 165335; TMC 125; TMC-125; TMC125; Etravirine. Intelence. Grades: >98%. CAS No. 269055-15-4. Molecular formula: C20H15BrN6O. Mole weight: 435.28. | |
| Euojaponine D | Euojaponine D is an alkaloid found in the Euonymus japonica. Synonyms: 19, 22, 23-Tris(acetyloxy)-21-[(acetyloxy)methyl]-25, 26-dihydroxy-3, 15, 26-trimethyl-6, 16-dioxo-2, 5, 17-trioxa-11-azapentacyclo[16.7.1.0~1, 21~.0~3, 24~.0~7, 12~]hexacosa-7, 9, 11-trien-20-yl benzoate. Grades: >98%. CAS No. 128397-42-2. Molecular formula: C41H47NO17. Mole weight: 825.817. | |
| Euphorbia Factor L2 | Euphorbia Factor L2 is a diterpenoid isolated from Euphorbia lathyris L with cytotoxic activity against lung carcinoma A549 cells. Synonyms: Euphorbia Factor L2; 218916-51-9. Grades: 0.98. CAS No. 218916-51-9. Molecular formula: C38H42O9. Mole weight: 642.7. | |
| Eupteleasaponin I | Eupteleasaponin I is a triterpenoid compound found in the leaves of Euptelea polyandra Sieb. et Zucc. Synonyms: (3beta)-3-[(O-6-Deoxy-alpha-L-mannopyranosyl-(1->2)-O-beta-D-glucopyranosyl-(1->3)-beta-D-xylopyranosyl)oxy]-30-noroleana-12,20(29)-dien-28-oic acid beta-D-glucopyranosyl ester. Grades: >98%. CAS No. 290809-29-9. Molecular formula: C52H82O21. Mole weight: 1043.19. | |
| Eurycomanone | Eurycomanone is a diterpenoid showing anti-cancer activity. Synonyms: Pasakbumin-A. Grades: 98%. CAS No. 84633-29-4. Molecular formula: C20H24O9. Mole weight: 408.4. | |
| Everolimus | Everolimus is an inhibitor of mammalian target of rapamycin (mTOR) with an immunosuppressive activity which is comparable to that of rapamycin. It inhibits cytokine-mediated lymphocyte proliferation. Everolimus can be used as an immunosuppressant in the treatment of renal cell cancer and other cancers. Uses: Immunosuppressant. Synonyms: RAD-001; RAD001; RAD 001; Afinitor; Certican; Zortress; RAD001; SDZ-RAD. Grades: >98%. CAS No. 159351-69-6. Molecular formula: C53H83NO14. Mole weight: 958.24. | |
| Evexomostat | Evexomostat is a methionine aminopeptidase 2 (MetAP2) inhibitor. Synonyms: poly ({N-[ (2RS) -2-hydroxypropyl]methacrylamide}-co-[N-methacryloylgly-cyl-L-phenylalanyl-L-leucyl-N1- (trans-4-{[ ({ (3R, 4S, 5S, 6R) -5-methoxy-4-[ (2R, 3R) -2-methyl-3- (3-methylbut-2-en-1-yl) oxiran-2-yl]-1-oxaspiro[2. 5]-octan-6-yl}oxy) carbonyl]amino}cyclohexyl) glycinamide (~0.91:0.09 x)]); poly([N-(2-hydroxypropyl)methacrylamide]-co-{methacryloyl-Gly-Phe-Leu-Gly amide with O-[ (trans-4-aminocyclohexyl) carbamoyl]fumagillol}). CAS No. 2416263-67-5. Molecular formula: [(C7H13NO2)n(C46H68N6O10)]m. | |
| Evixapodlin | Evixapodlin is a human programmed cell death ligand 1 (PD-1/PD-L1) protein/protein interaction inhibitor with an IC50 of 0.213 nM. It has anticancer and antiviral functions. Synonyms: (12S,122S)-62,72-dichloro-53,86-dimethoxy-3,10-diaza-5,8(2,5)-dipyrazina-1,12(2)-dipyrrolidina-6,7(1,3)-dibenzenadodecaphane-15,125-dione; (5S, 5'S)-5, 5'- ( ( ( (5, 5'- (2, 2'-dichloro-[1, 1'-biphenyl]-3, 3'-diyl)bis (3-methoxypyrazine-5, 2-diyl))bis (methylene))bis (azanediyl))bis (methylene))bis (pyrrolidin-2-one); 2-Pyrrolidinone, 5, 5'-[ (2, 2'-dichloro[1, 1'-biphenyl]-3, 3'-diyl) bis[ (3-methoxy-5, 2-pyrazinediyl) methyleneiminomethylene]]bis-, (5S,5'S)-; PD-1/PD-L1-IN 7. Grades: ≥98%. CAS No. 2374856-75-2. Molecular formula: C34H36Cl2N8O4. Mole weight: 691.61. | |
| Evolitrine | Evolitrine is an alkaloid isolated from Fructus Evodiae. Synonyms: Evolitrin; 4,7-dimethoxyfuro[2,3-b]quinoline. Grades: 98%. CAS No. 523-66-0. Molecular formula: C13H11NO3. Mole weight: 229.23. | |
| EW-7197 | EW-7197 is a potent and selective ALK5 inhibitor, displaying antimetastatic and anticancer effects. It inhibits TGF-β/Smad signaling, and abrogates TGF-β1-induced tumor cell migration and invasion. EW-7197 inhibits breast cancer metastasis to the lung. EW-7197 prolongs the life span of BALB/c 4T1 mice via inhibition of EMT. EW-7197 inhibits metastasis and enhances the activity of cytotoxic T lymphocytes (CTLs) in 4T1 orthotopic grafted mice. Synonyms: Vactosertib; N-(2-fluorophenyl)-5-(6-methyl-2-pyridinyl)-4-[1,2,4]triazolo[1,5-a]pyridin-6-yl-1H-imidazole-2-methanamine. Grades: >98%. CAS No. 1352608-82-2. Molecular formula: C22H18FN7. Mole weight: 399.433. | |
| Ex 26 | Ex 26 is a potent and selective S1P1 receptor antagonist (IC50 = 0.93 nM) with > 3,000-fold selectivity over S1P2, S1P3, S1P4 and S1P5. It causes lymphocyte sequestration in peripheral lymph nodes, and upregulates S1P1 receptor expression. Synonyms: 1-[[[5'-[[1-(4-Chloro-3-methylphenyl)ethyl]amino]-2'-fluoro-3,5-dimethyl[1,1'-biphenyl]-4-yl]carbonyl]amino]-cyclopropanecarboxylic acid. Grades: ≥98% by HPLC. CAS No. 1233332-37-0. Molecular formula: C28H28ClFN2O3. Mole weight: 494.98. | |
| Exenatide acetate | Exenatide acetate is a potent peptide agonist of the glucagon-like peptide 1 (GLP-1) receptor with Ki value of 136 pM. It is a 39 amino acid peptide, which increases intracellular cAMP in pancreatic acinar cells and has no effect on VIP receptors. It was first isolated from the venom of H. horridum and consequently synthesized. It stimulates proliferation of HCAECs through PKA-PI3K/Akt-eNOS activation pathways via a GLP-1 receptor-dependent mechanism. It also stimulates glucose-induced insulin secretion in isolated rat islets and proinsulin expression in mouse insulinoma βTC-1 cells. It protects hippocampal neurons against glutamate-induced apoptosis, suggesting utility in neurodegenerative diseases. It also has anxiolytic and anti-depressant effects and induces satiety. It is an incretin mimetic approved for type 2 diabetes mellitus treatment. It also has neurotrophic/protective activity in cellular and animal models of stroke, Alzheimer's and Parkinson's diseases. Synonyms: L-Serinamide, L-histidylglycyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-leucyl-L-seryl-L-lysyl-L-glutaminyl-L-methionyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-alanyl-L-valyl-L-arginyl-L-leucyl-L-phenylalanyl-L-isoleucyl-L-α-glutamyl-L-tryptophyl-L-leucyl-L-lysyl-L-asparaginylglycylglycyl-L-prolyl-L-seryl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-, acetate (1:x); Exendin 4 (Heloderma suspectum), acetate; Exendin-4 acetate; H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2.CH3CO2H. Grades: >98%. CAS No. 914454-01-6. Molecular formula: C184H282N50O60S.C2H4O2. Mole weight: 4246.61. | |
| Exo1 | Exo1 is a cell-permeable and reversible inhibitor of exocytosis (IC50 = 20 μM). Exo1 is a reversible inhibitor of vesicular trafficking between the endoplasmic reticulum and the Golgi apparatus. Exo1 releases ADP-ribosylation factor (ARF)1 from Golgi and disrupts the functions of Golgi. Synonyms: Benzoic acid, 2-[(4-fluorobenzoyl)amino]-, methyl ester; Methyl 2-[(4-fluorobenzoyl)amino]benzoate; 2-(4-Fluoro-benzoylamino)-benzoic acid methyl ester; NSC 214045; Exo1. Grades: 98%. CAS No. 75541-83-2. Molecular formula: C15H12FNO3. Mole weight: 273.26. | |
| Exo-Tetrahydrodicyclopentadiene | Exo-Tetrahydrodicyclopentadiene (CAS# 2825-82-3 ) is a useful research chemical. Synonyms: exo-Trimethylenenorbornane; (3aR,4S,7R,7aS)-rel-Octahydro-1H-4,7-methanoindene; JP-10. CAS No. 2825-82-3. Molecular formula: C10H16. Mole weight: 136.23. | |
| Eyeliss | Eyeliss is a cosmetic indegredient that has been used to relieve puffiness under eye bags and reduce dark circles beneath the eyes. Grades: 98%. | |
| (E,Z)-7,9-Dodecadienyl acetate | (E,Z)-7,9-Dodecadienyl acetate, a chemical compound commonly utilized in the fragrance industry due to its sweet and floral scent, also holds significance in the agricultural industry as a pheromone for luring male moths from the genus Grapholita known for causing damage to fruit trees. Its implications as a dual-use substance for distinct industries highlight the vast scope of its applications. Synonyms: 7,9-Dodecadienyl acetate, (7Z,9E)-; 7Z,9E-Dodecadienyl acetate. Grades: 98%. CAS No. 55774-32-8. Molecular formula: C14H24O2. Mole weight: 224.34. | |
| Ezetimibe 3-Fluoro Impurity | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L27) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4R)-1-(3-fluorophenyl)-3-(3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one. Grades: > 95%. CAS No. 1700622-06-5. Molecular formula: C24H21F2NO3. Mole weight: 409.44. | |
| Ezetimibe Dehydoxy Impurity | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L16) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: 3-Dehydroxy Ezetimibe; (3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)propyl]-4-(4-hydroxyphenyl)-2-azetidinone. Grades: > 95%. CAS No. 204589-58-2. Molecular formula: C24H21F2NO2. Mole weight: 393.44. | |
| Ezetimibe Desfluoro Methyl Impurity | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L30) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: 4"DeFluoro-4"methyl-ezetimibe; (3R,4S)-1-(4-Fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one. Grades: > 95%. CAS No. 1700622-07-6. Molecular formula: C25H24FNO3. Mole weight: 405.47. | |
| Ezetimibe Fluoro Isomer | A stereoisomer of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L9) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: 3'-(2-Fluorophenyl) Ezetimibe; (3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(2-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone. Grades: > 95%. CAS No. 1798008-25-9. Molecular formula: C24H21F2NO3. Mole weight: 409.44. | |
| Ezetimibe Ketone | Phase-I metabolite of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)-2-azetidinone. Grades: > 95%. CAS No. 191330-56-0. Molecular formula: C24H19F2NO3. Mole weight: 407.42. | |
| Ezetimibe Tetrahydropyran Impurity | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (2R,3R,6S)-N,6-Bis(4-fluorophenyl)tetrahydro-2-(4-hydroxyphenyl)-2H-pyran-3-carboxamide; SCH59566. Grades: > 95%. CAS No. 1296129-15-1. Molecular formula: C24H21F2NO3. Mole weight: 409.44. | |
| Ezurpimtrostat | Ezurpimtrostat is a palmitoyl protein thioesterase 1 (PPT-1) inhibitor. Synonyms: 4-(4-(tert-butylamino)piperidin-1-yl)-N-(4-chlorobenzyl)quinolin-2-amine. CAS No. 1914148-72-3. Molecular formula: C25H31ClN4. Mole weight: 423.00. | |
| Ezutromid | Ezutromid, also known as BMN-195 and SMTC-1100, is an orally bioavailable and non-toxic small molecule that transcriptionally upregulates the utrophin gene (EC50= 0.4 uM), increasing both utrophin mRNA and protein. It significantly reduces dystrophin-deficient muscle pathology in vivo. Synonyms: 5-(ethylsulfonyl)-2-(naphthalen-2-yl)benzo[d]oxazole; BMN-195; BMN 195; BMN195; SMTC-1100; SMTC1100; SMTC 1100; VOX-C1100; Ezutromid. CAS No. 945531-77-1. Molecular formula: C19H15NO3S. Mole weight: 337.39. | |
| Fabiatrin | Fabiatrin is a compound of the coumarin class found in the herbs of Thalictrum fortunei. Synonyms: 6-methoxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-2-one. Grades: >98%. CAS No. 18309-73-4. Molecular formula: C21H26O13. Mole weight: 486.426. | |
| FAD disodium salt | FAD disodium salt is the salt form of FAD, which is a coenzyme that facilitates the transfer of electrons by flavoenzymes in oxidation-reduction reactions in cells. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: FAD-Na2; FAD Na2; FADNa2; Flavin Adenine Dinucleotide Disodium Salt. CAS No. 84366-81-4. Molecular formula: C27H31N9Na2O15P2. Mole weight: 829.52. | |
| F-Amidine trifluoroacetate salt | F-amidine is an inhibitor of protein arginine deiminases (PADs) that is selective for PAD1 and PAD4 (IC50s = 29.5 and 21.6 μM for PAD1 and PAD4 in vitro, respectively). Synonyms: N-[(1S)-1-(aminocarbonyl)-4-[(2-fluoro-1-iminoethyl)amino]butyl]-benzamide, 2,2,2-trifluoroacetate. Grades: ≥95%. CAS No. 877617-46-4. Molecular formula: C14H19FN4O2·CF3COOH. Mole weight: 408.4. | |
| Famitinib | Famitinib is a novel multi-targeted receptor tyrosine kinase inhibitor under development for cancer treatment. Famitinib is a structural analogue ofsunitinib, is a novel and potent multi-targeted RTK inhibitor that is currently undergoing phase II clinical trials in China for the treatment of renal cell carcinoma, gastrointestinal stromal tumours, pancreatic cancer, and nasopharyngeal carcinoma. Compared with sunitinib, famitinib exhibits superior inhibition activities against multiple RTKs. Synonyms: 5-(2-diethylamino-ethyl)-2-(5-fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-3-methyl-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one; SHR1020; SHR 1020; SHR-1020; 4H-Pyrrolo[3,2-c]pyridin-4-one, 5-[2-(diethylamino)ethyl]-2-[(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-1,5,6,7-tetrahydro-3-methyl-. Grades: ≥98%. CAS No. 945380-27-8. Molecular formula: C23H27FN4O2. Mole weight: 410.48. | |
| Famotidine Impurity E | An impurity of Famotidine. Famotidine is a histamine H8 receptor antagonist that inhibits stomach acid production. Synonyms: Famotidine disulfide; Famotidine related compound E; Bis[(2-guanidino-4-thiazolyl)methyl]disulfide. Grades: > 95%. CAS No. 129083-44-9. Molecular formula: C10H14N8S4. Mole weight: 374.53. | |
| Fampridine Impurity 3 | A derivative of Fampridine. Fampridine is a potent convulsant. Synonyms: N-(4-Pyridyl)-2-Hydroxybutyramide; Butanamide, 2-hydroxy-N-4-pyridinyl-. Grades: > 95%. CAS No. 1864897-67-5. Molecular formula: C9H12N2O2. Mole weight: 180.21. | |
| Fanetizole mesylate | Fanetizole shows immunoregulating activity. Uses: An immunoregulator agent. Synonyms: Fanetizole mesylate; UNII-D3OG7B0G4M; Fanetizole mesylate (USAN); Fanetizole mesylate [USAN]; C1MHW3X; CP 48810; CP-48,810; fanetizole;2-(Phenethylamino)-4-phenylthiazole monomethanesulfonate. Grades: 98%. CAS No. 79069-95-7. Molecular formula: C18H20N2O3S2. Mole weight: 376.50. | |
| Faropenem potassium | Faropenem potassium is an orally active beta-lactam antibiotic. It is a prodrug of Faropenem and belongs to the penem group. It is resistant to some forms of extended-spectrum beta-lactamase. Synonyms: 4-Thia-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-7-oxo-3-(tetrahydro-2-furanyl)-, monopotassium salt, (5R-(3(R*),5-alpha,6-alpha(R*)))-;Potassium (1'R,2''R,5R,6S)-6-(1'-hydroxyethyl)-2-(2''-tetrahydrofuranyl)-penem-3-carboxylate;(5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2S)-oxolan-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate. Grades: >98%. CAS No. 106559-89-1. Molecular formula: C12H14KNO5S. Mole weight: 323.40. | |
| Fasentin | Fasentin is a GLUT1 and GLUT4 inhibitor (IC50 = 68 μM). Fasentin sensitizes Fas receptor in a range of tumor cell lines (IC50 = 20 μM) via regulating the extrinsic apoptotic pathway downstream of TNF receptors but upstream of effector caspases. Synonyms: N-(4-Chloro-3-(trifluoromethyl)phenyl)-3-oxobutanamide. Grades: ≥98% by HPLC. CAS No. 392721-37-8. Molecular formula: C11H9ClF3NO2. Mole weight: 279.64. | |
| Fasudil hydrochloride | Fasudil HCl, a 5-isoquinolinesulfonamide derivative, is a highly selective Rho-associated protein kinase inhibitor that might have a rate in romoting the recovery of neurological function, reducing clinical symptoms and the morbidity. Uses: Fasudil hcl, a 5-isoquinolinesulfonamide derivative, is a highly selective rho-associated protein kinase inhibitor that might have a rate in romoting the recovery of neurological function, reducing clinical symptoms and the morbidity. Synonyms: Fasudil HCl; Eril; Fasudil (Hydrochloride); Fasudil Monohydrochloride; AT-877; HA-1077; AT 877; HA 1077; AT877; HA1077. Grades: >98%. CAS No. 105628-07-7. Molecular formula: C14H18ClN3O2S. Mole weight: 327.83. | |
| Fatostatin A | Fatostatin (125B11) is an inhibitor of SREBP activation and prevents SCAP-mediated escort of SREBP-1 or SREBP-2 to the Golgi (IC50 = 5.6 μM). Fatostatin has anti-tumor properties and can reduce hyperglycemia in ob/ob mice. Synonyms: Fatostatin; 4-(4-Methylphenyl)-2-(2-Propyl-4-Pyridinyl)Thiazole; 125B11. Grades: 98%. CAS No. 125256-00-0. Molecular formula: C18H18N2S. Mole weight: 294.4. | |
| Fatostatin A hydrobromide | Fatostatin A is an inhibitor of sterol regulatory element binding protein (SREBP). Fatostatin A reverses hyperglycemia in diabetic (ob/ob) mice, and inhibits proliferation in DU 145 cells independently of IGF-1 signaling (IC50 = 0.1 μM). Uses: The treatment of some metabolic disorders. Synonyms: Fatostatin A; 4-[4-(4-Methylphenyl)-2-thiazolyl]-2-propylpyridine hydrobromide; 2-Propyl-4-(4-p-tolyl-thiazol-2-yl)-pyridine. Grades: ≥97% by HPLC. CAS No. 298197-04-3. Molecular formula: C18H18N2S.HBr. Mole weight: 375.33. | |
| Faxeladol | Faxeladol is an opioid analgesic with a higher rate of sudden seizures than tramadol. Uses: An opioid analgesic. Synonyms: GCR9905; GCR 9905; GCR-9905; EM-906; EM 906; EM906; GRT-TA300; GRTA9906; GRTA-9906; GRTA 9906; GRTA0009906; GRTA-0009906;GRTA 0009906; Faxeladol3- ( (1R, 2R) -2- ( (dimethylamino) methyl) cyclohexyl) phenol. Grades: ≥95%. CAS No. 433265-65-7. Molecular formula: C15H23NO. Mole weight: 233.36. | |
| FC131 | FC 131 is a CXCR4 antagonist with anti-HIV activity. Synonyms: FC 131; FC-131; FC131; d-Tyr-Arg-Arg-2-Nal-Gly; Cyclo[2-Nal-Gly-D-Tyr-Arg-Arg]. Grades: ≥95%. CAS No. 606968-52-9. Molecular formula: C36H47N11O6. Mole weight: 729.84. | |
| FCCP | As A very potent uncoupler of oxidative phosphorylation in mitochondria, FCCP transports protons across cell membranes which disrupts ATP synthesis. Uses: A very potent uncoupler of oxidative phosphorylation in mitochondria. Synonyms: 2- [ [4- (trifluoromethoxy) phenyl] hydrazinylidene] propanedinitrile. Grades: ≥98%. CAS No. 370-86-5. Molecular formula: C10H5F3N4O. Mole weight: 254.17. | |
| FCE 26644 | FCE 26644, also known as PNU-145156E, has been found to be a angiogenesis inhibitor that could have probable effect against solid tumours. It has already been discontined. Synonyms: PNU-145156E; PNU145156E; PNU 145156E; FCE26644; FCE-26644; FCE 26644. 7,7'-(Carbonyl-bis(imino-N-methyl-4,2-pyrrolcarbonylimino(N-methyl-4,2-pyrrol)carbonylimino))-bis(1,3-naphthalenedisulfonic acid); 1,3-Naphthalenedisulfonic acid, 7,7'-(carbonylbis(imino(1-methyl-1H-pyrrole-4,2-diyl)carb. Grades: 98%. CAS No. 154788-16-6. Molecular formula: C45H36N10Na4O17S4. Mole weight: 1209.04. | |
| FE-999024 | FE-999024, a dipeptide compound, has been found to be a kallikrein inhibitor that was once studied in pancreatitis by Ferring Pharmaceuticals. Synonyms: FE-999024; FE 999024; FE999024; CH-2856; CH2856; CH 2856; L-Alaninamide, 4-chloro-D-phenylalanyl-N-(3-((aminoiminomethyl)amino)propyl)-3-(1-naphthalenyl)-. Grades: 98%. CAS No. 168825-65-8. Molecular formula: C26H31ClN6O2. Mole weight: 495.02. | |
| Febrifugine dihydrochloride | Febrifugine is a quinazolinone alkaloid isolated from the Chinese herb Dichroa febrifuga. Synonyms: (+)-Febrifugine dihydrochloride. Grades: > 95%. CAS No. 32434-42-7. Molecular formula: C16H21Cl2N3O3. Mole weight: 374.26. | |
| Febuxostat Amide Impurity | An impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Synonyms: 2-[3-(Aminocarbonyl)-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic acid. Grades: >95%. CAS No. 1239233-86-3. Molecular formula: C16H18N2O4S. Mole weight: 334.40. | |
| Febuxostat Impurity 23 | An impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Grades: 95%. CAS No. 2073891-59-3. Molecular formula: C15H13NO5S. Mole weight: 319.33. | |
| Fenaclonum | Cas No. 306-20-7. | |
| Fenbufen | Fenbufen is a non-steroidal anti-inflammatory synthetic active reagent. Uses: A non-steroidal anti-inflammatory drug. Synonyms: 4-oxo-4-(4-phenylphenyl)butanoic acid. Grades: > 98 %. CAS No. 36330-85-5. Molecular formula: C16H14O3. Mole weight: 254.28. | |
| Fenitrooxone | Fenitrooxone is an intricately formulated biomedical agent, used for studying inflammation, malignancies and autoimmune dysfunctions. Synonyms: 3-Methyl-4-nitrophenyl dimethyl phosphate;3-methyl-4-nitrophenyldimethylphosphate;4-nitro-m-cresodimethylphosphate; Accothion O-analog; accothiono-analog; BAY 42247; bay42247; Dimethyl 3-methyl-4-nitrophenyl phosphate. Grades: >98%. CAS No. 2255-17-6. Molecular formula: C9H12NO6P. Mole weight: 261.17. | |
| Fenoprofen | Fenoprofen, a non-steroidal anti-inflammatory drug, acts as an anti-inflammatory analgesic and antipyretic highly bound to plasma proteins. Synonyms: Benzeneacetic acid, α-methyl-3-phenoxy-; Hydratropic acid, m-phenoxy-; α-Methyl-3-phenoxybenzeneacetic acid; (±)-2-(3-Phenoxyphenyl)propionic acid; (±)-Fenoprofen; (±)-m-Phenoxyhydratropic acid; 2-(3-Phenoxyphenyl)-1-propanoic acid; 2-(3-Phenoxyphenyl)propionic acid; 2-(m-Phenoxyphenyl)propionic acid; 3-Phenoxyhydratropic acid; dl-2-(3-Phenoxyphenyl)propionic acid; Lilly 53858; m-Phenoxyhydratropic acid. Grades: ≥96%. CAS No. 29679-58-1. Molecular formula: C15H14O3. Mole weight: 242.28. | |
| Fenoprofen calcium hydrate | Fenoprofen calcium hydrate is a non-steroidal anti-inflammatory drug (NSAID). Synonyms: NCI-C56086; NCI C56086; NCIC56086. Grades: >98%. CAS No. 71720-56-4. Molecular formula: C15H14O3·1/2 Ca·H2O. Mole weight: 242.27. | |
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