BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Fuziline | Fuziline is extracted from the roots of Aconitum carmichaeli Debx. Synonyms: Aconitane-1,8,14,15-tetrol, 20-ethyl-6,16-dimethoxy-4-(methoxymethyl)- , (1alpha, 6alpha, 14alpha, 15alpha, 16beta)-; 15-Epinagarine; 15-Hydroxyneoline; Senbusine C. Grades: >98%. CAS No. 80665-72-1. Molecular formula: C24H39NO7. Mole weight: 453.6. |  |
| FW1256 | Exogenous H2S, as we know, has anti-inflammatory effects both in macrophages and in animal models. FW1256 is a slow release H2S dononr and it is much more potent in cells. FW1256 may be useful for studies of H2S in biology and could also have future therapeutic value in inflammatory conditions. Uses: Anti-inflammation. Synonyms: FW1256; FW-1256; FW 1256. 2-phenyl-3H-benzo[d][1,3,2]oxazaphosphole 2-sulfide. Grades: 98%. CAS No. 117089-08-4. Molecular formula: C12H10NOPS. Mole weight: 247.25. | |
| FY26 (complex) | This active moleculr is a Os(II) anticancer drug candidate. It can generate reactive oxygen species and disrupt the redox balance in cancer cells. Using FY26 and nontoxic doses of L-BSO together allows the potentiation of its anticancer activity and inpartantly, it improves the selectivity for cancer cells versus normal fibroblasts. FY26 can shut down a cancer cell by exploiting weaknesses inherent in their energy generation. Uses: Anti-cancer. Synonyms: FY26; FY-26; FY 26. Osmium(1+)?, [N, ?N-dimethyl-4-[2-(2-pyridinyl-κN)?diazenyl-κN1]?benzenamine]?iodo[(1, ?2, ?3, ?4, ?5, ?6-η)?-1-methyl-4-(1-methylethyl)?benzene]?-, hexafluorophosphate(?1-) (1:1). Grades: 98%. CAS No. 1255143-82-8. Molecular formula: C23H28F6IN4OsP. Mole weight: 822.60. | |
| G244-LM | G244-LM is a potent and specific small-molecule tankyrase inhibitors, which reduces Wnt/β-catenin signaling by preventing poly(ADP-ribosyl)ation-dependent AXIN degradation, thereby promoting β-catenin destabilization. Synonyms: 3,5,7,8-tetrahydro-2-[4-[2-(methylsulfonyl)phenyl]-1-piperazinyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one. CAS No. 1563007-08-8. Molecular formula: C18H22N4O3S2. Mole weight: 406.5. | |
| G-36 | G-36 is an antagonist of G protein-coupled estrogen receptor (GPER). It selectively inhibits estrogen-mediated activation of PI3-K by GPER and estrogen-mediated calcium mobilization (IC50 = 112 nM). Synonyms: GRB-G36; G-36; G36; G 36. (±)-(3aR,4S,9bS)-4-(6-Bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-8-(1-methylethyl)-3H-cyclopenta[c]quinoline. Grades: ≥99% by HPLC. CAS No. 1392487-51-2. Molecular formula: C22H22BrNO2. Mole weight: 412.33. | |
| G-5555 | G-5555 is a selective PAK1 Inhibitor (Ki=3.7 nM) with low clearance (CLp = 3.4 mL/min/kg) and high oral bioavailability (F = 72%). IC50: PAK2= 11 nM, SIK2= 9 mM, KHS1= 10 mM. Synonyms: G - 5555; G 5555; G5555; 8-[(5-amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one59T8-(((2r,5r)-5-amino-1,3-dioxan-2-yl)methyl)-6-(2-chloro-4-(6-methylpyridin-2-yl)phenyl)-2-(methylamino)pyrido[2,3-d]pyrimidin-7. CAS No. 1648863-90-4. Molecular formula: C25H25ClN6O3. Mole weight: 492.96. | |
| G-5555 hydrochloride | G-5555 hydrochloride is the hydrochloride salt of G-5555 which is a potent and selective p21-activated kinase 1 (PAK1) inhibitor (Ki = 3.7 nM). G-5555 was potent, showing good activity in the pMEK cellular assay, had improved permeability, and importantly, displayed low hERG channel activity (<50% inhibition at 10 μM). Synonyms: 8-[(5-amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one;hydrochloride; G-5555 (hydrochloride); G 5555 (hydrochloride); G5555 (hydrochloride). Molecular formula: C25H26Cl2N6O3. Mole weight: 529.42. | |
| Gabexate | Gabexate mesylate is a serine protease inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation, and as a regional anticoagulant for haemodialysis. Uses: Serine protease inhibitor. Synonyms: GABEXATE; GabexateMesylateBase; [N'-[5- (4-ethoxycarbonylphenoxy) carbonylpentyl]carbamimidoyl]azanium methanesulfonate;4-[(6-Guanidinohexanoyl)oxy]benzoic acid ethyl ester;4-[[6-[[Amino(imino)methyl]amino]-1-oxohexyl]oxy]benzoic acid ethyl ester. Grades: ≥98%. CAS No. 39492-01-8. Molecular formula: C16H23N3O4. Mole weight: 321.375. | |
| Gadobutrol | Gadobutrol is a nonionic, paramagnetic contrast agent developed for tissue contrast enhancement in magnetic resonance imaging (MRI). It has a macrocyclic framework and is neutral. It is a water-soluble, highly hydrophilic compound with a partition coefficient between n-butanol and buffer at pH 7.6 of ~ 0.006. Uses: A gadolinium-based mri contrast agent (gbca). Synonyms: Gadograf; Gadovist; Protovist; ZK 135079; Gd-DO3A-butrol; Gallium 10-(1,3,4-trihydroxybutan-2-yl)-1,4,7,10-tetraazacyclododecane-1,4,7-tricarboxylate; AK325914; gallium. Grades: ≥99.5%. CAS No. 138071-82-6. Molecular formula: C18H31GdN4O9. Mole weight: 604.71. | |
| Gadodiamide | Gadodiamide(Omniscan) is a gadolinium-based MRI contrast agent, used in MR imaging procedures to assist in the visualization of blood vessels. Synonyms: Gadodiamide, Gd-Dtpa-Bma;Gadodiamide; DV 7572; DV-7572; DV7572; Omniscan; S 041; S-041; S041. Grades: >98%. CAS No. 131410-48-5. Molecular formula: C16H26GdN5O8. Mole weight: 573.66. | |
| Gadodiamide hydrate | Gadodiamide, a nonionic Gd3+ chelate, is frequently injected i.v. into magnetic resonance imaging (MRI) to enhance contrast. Grades: >98%. CAS No. 122795-43-1. Molecular formula: C16H28GdN5O9C16H28GdN5O9.xH2O. Mole weight: 591.67. | |
| Gadoquatrane | Gadoquatrane is a diagnostic imaging agent. Synonyms: rac-[{μ 4-2, 2', 2'', 2''', 2'''', 2'''''-[{(2R, 16Ξ )-3, 6, 12, 15-tetraoxo-1κ O3:2κ O15-9, 9-bis[(2-{(2Ξ )-2-[4, 7, 10-tris(carboxy-3κ 3O4, O7, O10:4κ 3O4', O7', O10'-methyl)-1, 4, 7, 10-tetraazacyclododecan-1-yl-3κ 4N1, N4, N7, N10:4κ 4N1', N4', N7', N10']-propanamido-3κ O:4κ O'}acetamido)methyl]-4, 7, 11, 14-tetraazaheptadecane-2, 16-diyl}bis(1, 4, 7, 10-tetraazacyclododecane-10, 1, 4, 7-tetrayl-1κ 4N1, N4, N7, N10:2κ 4N1', N4', N7', N10')]hexaacetato-1κ 3O1, O4, O7:-2κ 3O1', O4', O7'}(12-)]tetragadolinium. CAS No. 2048221-65-2. Molecular formula: C81H128Gd4N24O32. Mole weight: 2579.05. | |
| Gadoteric acid | Gadoteric acid is a macrocycle-structured gadolinium-based MRI contrast agent (GBCA). It is used for imaging of blood vessels. Synonyms: Gadoterate; DOTA-Gd; Gd-Dota; Gadolinium 2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetic acid. Grades: 95%. CAS No. 72573-82-1. Molecular formula: C16H25GdN4O8. Mole weight: 558.65. | |
| Galactoarabinan | Galactoarabinan is a dietary fiber composed of arabinose and galactose monosaccharides. Arabinogalactan can stimulate natural killer (NK) cell cytotoxicity, enhance other functional aspects of the immune system, and inhibit the metastasis of tumor cells to the liver. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: D-Galacto-L-arabinan. CAS No. 9036-66-2. Molecular formula: ([C5H8O4][C6H10O5]6)x. | |
| Galanin (2-29) (rat) | Galanin (2-29) (rat) is a peptide agonist of galanin receptors displaying selectivity for GAL2 (Ki = 85, 1.9 and 12.6 nM at rat GAL1, GAL2 and GAL3 receptors, respectively). Synonyms: 2-29-Galanin(rat)(9ci). CAS No. 141696-11-9. Molecular formula: C144H210N42O39. Mole weight: 3153.519. | |
| Galanin (rat, mouse) trifluoroacetate salt | Galanin is a 29 amino acid, C-terminally amidated neuropeptide with diverse biological activities. Galanin binds to rat galanin (GAL) receptor subtypes GAL1-3 (IC50s = 0.339, 1.35, and 3.31 nM, respectively) and human GAL1-3 (IC50s = 0.288, 1.62, and 12.3 nM, respectively). Synonyms: GAL (rat, mouse); Galanin (1-29) (rat, mouse). Grades: ≥95%. Molecular formula: C141H211N43O41·xCF3COOH. Mole weight: 3164.45. | |
| Galeterone | Galeterone (TOK-001 or VN/124-1) is a novel antiandrogen under development by Tokai Pharmaceuticals for the treatment of prostate cancer. It possesses a unique dual mechanism of action, acting as both anandrogen receptor antagonist and an inhibitor of CYP17A1, an enzyme required for the biosynthesis of theandrogens. Synonyms: TOK-001; TOK 001; TOK001; NX41765; NX 41765; NX-41765; VN 124; VN124; VN-124; VN/124-1; (3S,8R,9S,10R,13S,14S)-17-(benzimidazol-1-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-ol. Grades: >98%. CAS No. 851983-85-2. Molecular formula: C26H32N2O. Mole weight: 388.555. | |
| Gallein | Gallein is an inhibitor of G protein βγ subunit-dependent signaling leading to the inhibition of neutrophil chemotaxis and inflammation. It blocks PI 3-kinase and Rac1 activation in HL60 cells. Synonyms: 3',4',5',6'-Tetrahydroxyspiro[isobenzofuran-1(3H),9'-(9H)xanthen]-3-one; Alizarin violet; Pyrogallolphthalein; C.I. Mordant Violet 25; 4,5-Dihydroxyfluorescein. Grades: ≥97%. CAS No. 2103-64-2. Molecular formula: C20H12O7. Mole weight: 364.31. | |
| (-)-Gallocatechin | (-)-Gallocatechin had been shown to have moderate affinity to the human cannabinoid receptor. Synonyms: (2S,3R)-2-(3,4,5-Trihydroxyphenyl)chroman-3,5,7-triol; (2S,3R)-gallocatechin; ent-gallocatechin. Grades: >98%. CAS No. 3371-27-5. Molecular formula: C15H14O7. Mole weight: 306.27. | |
| Galloflavin | Galloflavin is a novel inhibitor of both the A and B isoforms of lactate dehydrogenase (Kis = 5.46 and 15.06 μM, respectively). It has also been shown to be a potential anticancer agent. Synonyms: NSC 107022; 3,8,9,10-tetrahydroxy-pyrano[3,2-c][2]benzopyran-2,6-dione. Grades: ≥98%. CAS No. 568-80-9. Molecular formula: C12H6O8. Mole weight: 278.2. | |
| GalNAc-INF7 | GalNAc (N-Acetylgalactosamine) has been used as a targeting ligand in antisense oligonucleotides (ASO) and siRNA therapeutics. INF7 peptide is a glutamine-enriched analogue of the membrane-disruptive segment of HA2 (amino acids 1-23) with greater pH sensitivity. Synonyms: GalNAc-CGLFEAIEGFIENGWEGMIDGWYG. Molecular formula: C189H303N39O70S2. Mole weight: 4305.78. | |
| GalNAc trimer-Cy5.5 | GalNAc (N-Acetylgalactosamine) has been used as a targeting ligand in antisense oligonucleotides (ASO) and siRNA therapeutics. Cy5.5 (Cyanine-5.5) is a cyanine dye. Synonyms: GalNAc trimer-Cyanine5.5. Molecular formula: C112H172N13O33. Mole weight: 2228.63. | |
| Galnon | Galnon is a non-peptide galanin GAL1 and GAL2 receptor agonist (Ki = 11.7 and 34.1 μM, respectively) with anticonvulsant, anxiolytic, anorectic and amnestic activities. It stimulates insulin release in isolated pancreatic islets from normal and diabetic rats. Synonyms: 3-Cyclohexyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-lysinamide; L-Lysinamide, 3-cyclohexyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-; Fmoc-b-cyclohexyl-Ala-Lys-AMC. Grades: ≥95% by HPLC. CAS No. 475115-35-6. Molecular formula: C40H46N4O6. Mole weight: 678.83. | |
| Galunisertib | Galunisertib is a potent and selective inhibitor of transforming growth factor beta receptor (TGF-βR) kinase. It was shown to inhibit self-renewal of cancer stem cells. Synonyms: LY 2157299; LY-2157299; 4-[2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline-6-carboxamide. Grades: >98%. CAS No. 700874-72-2. Molecular formula: C22H19N5O. Mole weight: 369.428. | |
| Gambogenic acid | Gambogenic Acid is a natural compound isolated from Garcinia hanburyi Hook. f. It shows anticancer activity. Grades: 98%. CAS No. 173932-75-7. Molecular formula: C38H46O8. Mole weight: 630.8. | |
| Gambogic acid | Gambogic acid is a natural product inhibitor of Hsp90. Synonyms: B-Guttiferrin; Beta-Guttiferrin; Beta-Guttilactone; Cambogic acid; Guttatic acid; Guttic acid. Grades: >95%. CAS No. 2752-65-0. Molecular formula: C38H44O8. Mole weight: 628.76. | |
| γ-Cyclodextrin | γ-Cyclodextrin is an impurity of sugammadex, a cyclodextrin agent indicated for the treatment of neuromuscular blockade induced by rocuronium and vecuronium. It inactivates rocuronium by encapsulating (chelating) the free molecule to form a stable complex. Synonyms: Cyclooctapentylose; gamma-Cyclodextrin; Cyclooctaamylose; Cyclomaltooctaose. Grades: ≥ 98%. CAS No. 17465-86-0. Molecular formula: C48H80O40. Mole weight: 1297.12. | |
| γ-Glu-Glu | Gamma-L-glutamyl-L-glutamic acid is a dipeptide that plays a role in cellular metabolism. It activates N-methyl-D-aspartate (NMDA) receptors in rats. Synonyms: gamma-L-Glutamyl-L-glutamic acid; (S)-2-((S)-4-Amino-4-carboxybutanamido)pentanedioic acid; g-Glutamylglutamic acid. Grades: ≥98% by HPLC. CAS No. 1116-22-9. Molecular formula: C10H16N2O7. Mole weight: 276.24. | |
| γ-Tocopherol | γ-Tocopherol is a form of vitamin E, a class of eight fat-soluble compounds. It shows less antioxidant activity than alpha-tocopherol. Vitamin supplement in health care products. Uses: Ingredient of health care products. Synonyms: (2R)-3,4-Dihydro-2,7,8-Trimethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-ol; (+)-2,7,8-Trimethyl-(7-methyl-d3)-2-(4,8,12-trimethyltridecyl)-6-chromanol; (+)-γ-Tocopherol; (2R,4'R,8'R)-γ-Tocopherol; (R,R,R)-γ-Tocopherol; D-γ-Tocopherol; all-(R)-γ-Tocopherol; d-γ-Tocopherol. Grades: 95%. CAS No. 54-28-4. Molecular formula: C28H48O2. Mole weight: 416.69. | |
| Ganciclovir EP Impurity C | Ganciclovir EP Impurity C is an Impurity of Ganciclovir. It is a sugar modified acyclic analogue of guanosine. It has potential to exhibit virucidal activity. Synonyms: 2'-Monodehydroxy-2'-chloro Ganciclovir; 9-[[2-Chloro-1- (hydroxymethyl) ethoxy]methyl]guanine; 2-Amino-9-[[2-chloro-1-(hydroxymethyl)ethoxy]methyl]-1,9-dihydro-6H-purin-6-one. Grades: > 95%. CAS No. 108436-36-8. Molecular formula: C9H12ClN5O3. Mole weight: 273.68. | |
| Ganciclovir Monopropionate | Ganciclovir Monopropionate is a potential prodrug of Ganciclovir. It was also found to exhibit anti-viral activity through experimental studies. Synonyms: Ganciclovir Mono-O-propionate; Ganciclovir Impurity B; 2-Amino-1,9-dihydro-9-[[1-(hydroxymethyl)-2-(1-oxopropoxy)ethoxy]methyl]-6H-purin-6-one. Grades: > 95%. CAS No. 194159-18-7. Molecular formula: C12H17N5O5. Mole weight: 311.30. | |
| Ganciclovir Sodium | Ganciclovir Sodium is a potent inhibitor of the Herpesvirus family including cytomegalovirus. It is an acyclovir analog. It is used to treat complications from AIDS-associated cytomegalovirus infections. It was developed by Roche and has been listed. Uses: Ganciclovir sodium is used to treat complications from aids-associated cytomegalovirus infections. Synonyms: 2-Amino-1,9-dihydro-9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-6h-purin-6-one sodium salt;9-[[1-(Hydroxymethyl)-2-hydroxyethoxy]methyl]-2-amino-9H-purine-6(1H)-one/sodium,(1:1) salt;Ganciclovir monosodium salt;6H-Purin-6-one, 1,9-dihydro-2-amino-9-((2-hydroxy-1-(hydroxymethyl)ethoxy)methyl)-, monosodium salt;RS-21592 sodium;RS21592 Sodium;Sodium 2-amino-9-(1,3-dihydroxypropan-2-yloxymethyl)purin-6-olate. Grades: 98%. CAS No. 107910-75-8. Molecular formula: C9H12N5NaO4. Mole weight: 277.21. | |
| Ganirelix Acetate | Ganirelix acetate is a decapeptide GnRH antagonist. It acts by blocking the action of GnRH upon the pituitary, thus rapidly suppressing the production and action of LH and FSH. It is primarily used in assisted reproduction to control ovulation. Synonyms: Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-hArg(Et,Et)-Leu-hArg(Et,Et)-Pro-D-Ala-NH2.2CH3CO2H; Antagon; N-Acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N6-[bis(ethylamino)methylene]-D-lysyl-L-leucyl-N6-[bis(ethylamino)methylene]-L-lysyl-L-prolyl-D-alaninamide diacetate; Orgalutran. Grades: 98%. CAS No. 129311-55-3. Molecular formula: C84H121ClN18O17. Mole weight: 1690.42. | |
| Ganirelix Impurity F | Ganirelix Impurity F is an impurity of Ganirelix Acetate. Synonyms: AC-D-2-NAL-D-4-CLPHE-D-3-PAL; N-Acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanine. Grades: > 95%. CAS No. 129225-22-5. Molecular formula: C32H31ClN4O5. Mole weight: 587.08. | |
| Ganoderenic acid C | Ganoderenic acid C is a triterpenoid compound found in the fruit body of Ganoderma lucidum. Synonyms: (3β,7β,15α,20E)-3,7,15-Trihydroxy-11,23-dioxo-lanosta-8,20(22)-dien-26-oic acid. Grades: >98%. CAS No. 100665-42-7. Molecular formula: C30H44O7. Mole weight: 516.675. | |
| Ganoderenic acid E | Ganoderenic acid E is a natural compound derived from Ganoderma lucidum that exhibits anticancer and anti-inflammatory properties. It has been shown to inhibit the growth of various cancer cells and reduce inflammation in experimental models. Grades: >98%. CAS No. 110241-23-1. Molecular formula: C30H40O8. Mole weight: 528.642. | |
| Ganoderic acid C2 | Ganoderic acid C2 is a triterpenoid compound found in the fruit body of Ganoderma lucidum. Ganoderic Acid C2 exhibits inhibitory effect on tumor and inflammations. Synonyms: Lanost-8-en-26-oic acid, 3,7,15-trihydroxy-11,23-dioxo-, (3β,7β,15α,25R)-; (3β,7β,15α,25R)-3,7,15-Trihydroxy-11,23-dioxolanost-8-en-26-oic acid; Ganoderic acid C 2; (2R,6R)-2-methyl-4-oxo-6-((3S,5R,7S,10S,13R,14R,15S,17R)-3,7,15-trihydroxy-4,4,10,13,14-pentamethyl-11-oxo-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)heptanoic acid. Grades: >98%. CAS No. 103773-62-2. Molecular formula: C30H46O7. Mole weight: 518.68. | |
| Ganoderic acid D | Ganoderic acid D (GAD) is one of the major components in Ganoderma triterpenes. GAD treatment for 48 h inhibited the proliferation of HeLa human cervical carcinoma cells with an IC(50) value of 17.3 +/- 0.3 microM. Synonyms: Ganoderic Acid D; 108340-60-9; GanodericacidD; Ganodernic acid D; SCHEMBL3676373; CHEMBL2205002; HY-N1511; BDBM50021402; AKOS032946021; MS-29559; CS-0017054; (6R)-6-[(5R,7S,10S,13R,14R,17R)-7-hydroxy-4,4,10,13,14-pentamethyl-3,11,15-trioxo-1,2,5,6,7,12,16,17-octahydrocyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxoheptanoic acid. Grades: >98%. CAS No. 108340-60-9. Molecular formula: C30H42O7. Mole weight: 514.6. | |
| Ganoderic acid D2 | Ganoderic acid D2 is a triterpenoid compound found in the fruit body of Ganoderma lucidum. Synonyms: 7,12-Dihydroxy-3,11,15,23-tetraoxolanost-8-en-26-oic acid; 7,12-Dihydroxy-3,11,15,23-tetraoxo-(7beta,12beta)-Lanost-8-en-26-oic acid. Grades: >98%. CAS No. 97653-94-6. Molecular formula: C30H42O8. Mole weight: 530.65. | |
| Ganoderic acid F | Ganoderic acid F, an organic natural compound, emanates from Ganoderma lucidum, a fungus. Well-recognized for its remarkable anti-inflammatory attributes, it constitutes a crucial constituent in the research of chronic inflammatory ailments encompassing arthritand asthma. Grades: >98%. CAS No. 98665-14-6. Molecular formula: C32H42O9. | |
| Ganoderic acid G | Ganoderic acid G is an exquisite natural compound extracted from Ganoderma lucidum,mainly used for studying hepatic ailments, neoplastic disorders and inflammatory responses. This intriguing molecule has remarkable attributes encompassing potent antioxidative and anti-cancerous actions. Synonyms: (3beta,7beta,12beta)-3,7,12-trihydroxy-11,15,23-trioxolanost-8-en-26-oic acid. Grades: >98%. CAS No. 98665-22-6. Molecular formula: C30H44O8. | |
| Ganoderic acid I | Ganoderic acid I is a triterpenoid compound found in the fruit body of Ganoderma lucidum. Synonyms: 6-[(3S,5R,7S,10S,13R,14R,17S)-3,7-dihydroxy-4,4,10,13,14-pentamethyl-11,15-dioxo-2,3,5,6,7,12,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-hydroxy-2-methyl-4-oxoheptanoic acid. Grades: >98%. CAS No. 98665-20-4. Molecular formula: C30H44O8. Mole weight: 532.674. | |
| Ganoderic acid LM2 | Ganoderic acid LM2 is a triterpenoid compound found in the fruit body of Ganoderma lucidum. Synonyms: (7beta,23S,24E)-7,23-Dihydroxy-3,11,15-trioxo-lanosta-8,24-dien-26-oic acid. Grades: >98%. CAS No. 508182-41-0. Molecular formula: C30H42O7. Mole weight: 514.65. | |
| Ganoderlactone D | Ganoderlactone D is a triterpenoid compound found in the fruit body of Ganoderma lucidum. Synonyms: Chol-8-en-24-oicacid, 3,7,12,20-tetrahydroxy-4,4,14-trimethyl-11,15-dioxo-, g-lactone,(3b,5a,7b,12b)-. Grades: >98%. CAS No. 1801934-15-5. Molecular formula: C27H38O7. Mole weight: 474.26. | |
| Ganolactone B | Ganolactone B is a lanostane triterpenoid isolated from the fruit body of Ganoderma lucidum. Synonyms: 3beta,7beta-Dihydroxy-11,15-dioxolanost-8-en-24->20 lactone. Grades: >98%. CAS No. 1028449-53-7. Molecular formula: C27H38O6. Mole weight: 458.59. | |
| GANT-61 | GANT 61 is a GLI antagonist that inhibits GLI1 activation of gene expression with an IC50 value of 5 μM. Synonyms: GANT61; GANT-61; GANT 61; NSC 136476; NSC136476; NSC-136476; 2-[[3-[[2-(dimethylamino)phenyl]methyl]-2-pyridin-4-yl-1,3-diazinan-1-yl]methyl]-N,N-dimethylaniline. Grades: >98%. CAS No. 500579-04-4. Molecular formula: C27H35N5. Mole weight: 429.612. | |
| Gap 27 | Gap 27, a peptide derived from connexin 43, is a gap junction inhibitor. Synonyms: H-Ser-Arg-Pro-Thr-Glu-Lys-Thr-Ile-Phe-Ile-Ile-OH; L-seryl-L-arginyl-L-prolyl-L-threonyl-L-alpha-glutamyl-L-lysyl-L-threonyl-L-isoleucyl-L-phenylalanyl-L-isoleucyl-L-isoleucine; Gap27; Gap-27. Grades: 98%. CAS No. 198284-64-9. Molecular formula: C60H101N15O17. Mole weight: 1304.53. | |
| Gardoside | Gardoside is found in the fruits of Gardenia jasminoides. Synonyms: Gardoside; 54835-76-6; (1S,4aS,6S,7aS)-6-hydroxy-7-methylidene-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4a,5,6,7a-tetrahydro-1H-cyclopenta[c]pyran-4-carboxylic acid; CHEMBL3622810; CHEBI:80827. Grades: > 95%. CAS No. 54835-76-6. Molecular formula: C16H22O10. Mole weight: 374.34. | |
| Gastrin-Releasing Peptide, human | Gastrin-Releasing Peptide, human (GRP), one of the bombesin-like peptide family, is an agonist for the gastrin-releasing peptide receptor (GRPR) and it plays only a perfunctory role in the mediation of pituitary hormone release. Synonyms: Gastrin-Releasing Peptide, human; H-Val-Pro-Leu-Pro-Ala-Gly-Gly-Gly-Thr-Val-Leu-Thr-Lys-Met-Tyr-Pro-Arg-Gly-Asn-His-Trp-Ala-Val-Gly-His-Leu-Met-NH2. CAS No. 93755-85-2. Molecular formula: C130H204N38O31S2. Mole weight: 2859.38. | |
| GAT-100 | GAT-100, an indole derivative, has been found to be a negative allosteric modulator that could be used as a covalent probe in studying of the binding motifs of CB1R-allosteric ligand. Synonyms: GAT100; GAT-100; GAT 100; 3-ethyl-5-isothiocyanato-N-(4-(piperidin-1-yl)phenethyl)-1H-indole-2-carboxamide. Grades: 98%. CAS No. 1663564-42-8. Molecular formula: C25H28N4OS. Mole weight: 432.59. | |
| Gboxin | Gboxin is an oxidative phosphorylation inhibitor in cancer cells, which inhibits the activity of F0F1 ATP synthase. Synonyms: 2-ethyl-1-methyl-3-[2-[[(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl]oxy]-2-oxoethyl]-1H-benzimidazolium, monochloride. Grades: ≥98%. CAS No. 2101315-36-8. Molecular formula: C22H33N2O2·Cl. Mole weight: 392.96. | |
| GDC-0339 | GDC-0339, also called as SCHEMBL14801965, is a selective inhibitor of BaF3 PIM1 that has the potential for treatment of cancer. BaF3 PIM1: IC50= 43.6 nM; PIM1 LC-3K: IC50= 0.04 nM. Synonyms: 5-amino-N-[5-[(4R,5R)-4-amino-5-fluoroazepan-1-yl]-1-methylpyrazol-4-yl]-2-(2,6-difluorophenyl)-1,3-thiazole-4-carboxamideGDC-0339; GDC 0339; GDC0339;SCHEMBL14801965BDBM110706CS-4775; HY-16976; CS 4775; HY 16976; CS4775; HY16976; US8614206, 139. CAS No. 1428569-85-0. Molecular formula: C20H22F3N7OS. Mole weight: 465.50. | |
| GDC-0853 | GDC-0853 is a Bruton's tyrosine kinase (BTK) inhibitor originated by Genentech. GDC-0853 can inhibit the activity of BTK and prevent the activation of the B-cell antigen receptor (BCR) signaling pathway. This leads to the inhibition of the growth of malignant B-cells that overexpress BTK. Phase III clinical trials for the treatment of Multiple sclerosis and Phase II clinical trials for the treatment of Chronic urticaria and Systemic lupus erythematosus are on-going. Uses: Rheumatoid arthritis; autoimmune disorders. Synonyms: Fenebrutinib; RG 7845; RG7845; GDC0853; RG-7845; GDC 0853; (S)-2-(3'-(hydroxymethyl)-1-methyl-5-((5-(2-methyl-4-(oxetan-3-yl)piperazin-1-yl)pyridin-2-yl)amino)-6-oxo-1,6-dihydro-[3,4'-bipyridin]-2'-yl)-7,7-dimethyl-3,4,7,8-tetrahydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1(6H)-one. Grades: 98%. CAS No. 1434048-34-6. Molecular formula: C37H44N8O4. Mole weight: 664.81. | |
| GDC-0994 | GDC-0994, also known as RG7842, is an orally available inhibitor of extracellular signal-regulated kinase (ERK), with potential antineoplastic activity. Upon oral administration, GDC-0994 inhibits both ERK phosphorylation and activation of ERK-mediated signal transduction pathways. This prevents ERK-dependent tumor cell proliferation and survival. The mitogen-activated protein kinase (MAPK)/ERK pathway is upregulated in a variety of tumor cell types and plays a key role in tumor cell proliferation, differentiation and survival. Uses: Antineoplastic agents. Synonyms: GDC0994; GDC 0994; RG7842; RG-7842; RG 7842; Ravoxertinib. CAS No. 1453848-26-4. Molecular formula: C21H18ClFN6O2. Mole weight: 440.863. | |
| GDP366 | GDP366 is a novel small molecule compound which potently and selectively inhibited the expression of both survivin and Op18. GDP366 induces cell growth inhibition, cellular senescence and mitotic catastrophe in human cancer cells. Synonyms: 1-[4-(4-aminothieno[2,3-d]pyrimidin-5-yl)phenyl]-3-(3-methylphenyl)urea; GDP 366; GDP-366; GDP366. CAS No. 501698-03-9. Molecular formula: C20H17N5OS. Mole weight: 375.45. | |
| GDP-D-mannose disodium salt | GDP-D-mannose disodium salt is an invaluable compound, playing a pivotal role in the research of disorders pertaining to compromised glucose metabolism. Functioning as a critical intermediate within biosynthetic pathways, it specifically facilitates the synthesis of sugar nucleotides. Synonyms: Guanosine 5-diphospho-a-D-mannose disodium salt; GDP-Man. CAS No. 103301-73-1. Molecular formula: C16H23N5O16P2Na2. Mole weight: 649.3. | |
| GDP-L-fucose disodium salt | Substrate for fucosyltransferase. Synonyms: Guanosine 5'-pyrophosphate, β-L-fucopyranosyl ester Disodium Salt; Guanosine pyrophosphate, L-fucosyl ester Disodium Salt; Guanosine diphosphofucose Disodium Salt; Guanosine diphosphate fucose Disodium Salt; Guanosine 5'-pyrophosphate, L-fucosyl ester Disodium Salt; Guanosine 5'-diphospho-β-L-fucose Disodium Salt; GDP-Fucose Disodium Salt. Grades: ≥95%. CAS No. 148296-47-3. Molecular formula: C16H23N5O15P2Na2. Mole weight: 633.31. | |
| Gefarnate | Gefarnate is a drug used for the treatment of gastritis and gastric ulcer, in vivo, the instillation of gefarnate reduced corneal epithelial damage from desiccation in a dose-dependent fashion. Besides Gefarnate has been proposed for use in the treatment of dry eye syndrome. Synonyms: [(2E)-3,7-dimethylocta-2,6-dienyl] (4E,8E)-5,9,13-trimethyltetradeca-4,8,12-trienoate; Farnesylacetate, Geranyl; Gefarnate; Gefarnil; Gepharnate; Geranyl Farnesylacetate; Ulco. CAS No. 51-77-4. Molecular formula: C27H44O2. Mole weight: 400.64. | |
| Gefitinib Impurity II | Synonyms: N-(3-chloro-4-fluorophenyl)-6 ,7-dimethoxyquinazolin-4-amine. Grades: > 95%. CAS No. 153437-78-6. Molecular formula: C16H13ClFN3O2. Mole weight: 333.75. | |
| Gemcadiol | Gemcadiol is a new antilipemic drug with lipid-regulating properties. Uses: Antilipemic. Synonyms: CI-720; CI 720; CI720;2,2,9,9-Tetramethyl-1,10-decanediol. Grades: ≥98%. CAS No. 35449-36-6. Molecular formula: C14H30O2. Mole weight: 230.389. | |
| Gemcitabine hydrochloride | Gemcitabine induced NF-κB activity in BxPC-3, PANC-1, and MIA PaCa-2 cells and decreased the level of the NF-κB inhibitor IκBα in BxPC-3 and PANC-1 cells. Uses: Antimetabolites, antineoplastic. Synonyms: Gemzar; Gemcitabine HCl; LY188011 hydrochloride. Grades: >98%. CAS No. 122111-03-9. Molecular formula: C9H11F2N3O4.HCI. Mole weight: 299.66. | |
| Gemilukast 8 hydrate and disodium salt). | Gemilukast 8 hydrate and disodium salt is an exceptional compound harnessed to studying inflammatory ailments, such as asthma and allergic rhinitis. Synonyms: 1H-Indole-1,?3-dibutanoic acid, 4-fluoro-7-[2-[4-[4- (3-fluoro-2-methylphenyl) ?butoxy]?phenyl]?ethynyl]?-2-methyl-, sodium salt, hydrate (1:2:8). Grades: 98%. CAS No. 1232873-69-6. Molecular formula: C36H37F2NO5.8H2O.2Na. Mole weight: 601.69. | |
| Gemilukast disodium salt | Gemilukast, also known as ONO-6950, is an orally active dual CysLT1 and CysLT2 antagonist. Gemilukast exhibited antagonist activities with IC50 values of 1.7 and 25 nM against human CysLT1 and human CysLT2, respectively. Synonyms: 1H-Indole-1,?3-dibutanoic acid, 4-fluoro-7-[2-[4-[4- (3-fluoro-2-methylphenyl) ?butoxy]?phenyl]?ethynyl]?-2-methyl-, sodium salt (1:2). Grades: 98%. CAS No. 1232861-64-1. Molecular formula: C36H37F2NO5.2Na. Mole weight: 647.67. | |
| Gemnelatinib | Gemnelatinib is a tyrosine kinase inhibitor, with antineoplastic activity. Synonyms: (3R)-25-fluoro-3,81-dimethyl-26-oxo-26H-6-oxa-5(2,5)-pyrimidina-1(2),2(3,1)-dipyridina-8(4)-piperidina-4(1,3)-benzenaoctaphane-14-carbonitrile; (R)-5'-fluoro-1'-(1-(3-(5-((1-methylpiperidin-4-yl)methoxy)pyrimidin-2-yl)phenyl)ethyl)-6'-oxo-1',6'-dihydro-[2,3'-bipyridine]-4-carbonitrile. CAS No. 2225123-30-6. Molecular formula: C30H29FN6O2. Mole weight: 524.60. | |
| Genistein 7,4'-di-O-β-D-glucopyranoside | Genistein 7,4'-di-O-β-D-glucopyranoside is a comopund of the flavonoid class found in the aerial parts of Lupinus hartwegi. Synonyms: Genistein 4',7-di-β-D-glucopyranoside; 7-(β-D-Glucopyranosyloxy)-3-[4-(β-D-glucopyranosyloxy)phenyl]-5-hydroxy-4H-1-benzopyran-4-one; Genistein 4',7-diglucoside. Grades: >98%. CAS No. 36190-98-4. Molecular formula: C27H30O15. Mole weight: 594.52. | |
| Genistein 7-O-β-D-glucopyranoside-4'-O-[α-L-rhamnopyranosyl-(1?2)-β-D-glucopyranoside] | A compound of the flavonoid class. Synonyms: 2-(4-(((2S,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-3-hydroxyphenyl)-5-hydroxy-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one; Genistein 7-O-|A-D-glucopyranoside-4'-O-[|A-L-rhamnopyranosyl-(1 inverted exclamation marku2)-|A-D-glucopyranoside]; HY-N5129; VCA40442; Genistein 7-O-beta-D-glucopyranoside-4'-O-[alpha-L-rhamnopyranosyl-(1-->2)-beta-D-glucopyranoside]; CS-0032481; Genistein 7-O-(2)-D-glucopyranoside-4-O-[+/--L-rhamnopyranosyl-(1'2)-D-glucopyranoside]. Grades: >98%. CAS No. 70404-42-1. Molecular formula: C33H40O20. Mole weight: 756.66. | |
| Gentamycin sulfate | Cas No. 1405-41-0. | |
| Gentiournoside D | Gentiournoside D is a compound of the iridoids found in the Gentiana urnula. Synonyms: (1S,4aS,6S,7R,7aS)-6-[(2,3-Dihydroxybenzoyl)oxy]-1-(beta-D-glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-7-methylcyclopenta[c]pyran-4-carboxylic acid. Grades: >98%. CAS No. 157722-21-9. Molecular formula: C23H28O13. Mole weight: 512.46. | |
| Genz-123346 | Genz-123346 is an inhibitor of GL1 synthase that blocks the conversion of ceramide to GL1. It does not inhibit α-glucosidase or glucocerebrosidase. It lowered glucose and A1C levels and improved glucose tolerance in the Zucker diabetic fatty rat. Synonyms: Genz-123346; Genz123346; Genz 123346. Grades: >98%. CAS No. 943344-58-9. Molecular formula: C52H82N4O14. Mole weight: 987.23. | |
| Genz-123346 Free base | Genz-123346 is a glucosylceramide synthase inhibitor with potential anticancer activity. Exposure of cells to Genz-123346 and to other GCS inhibitors at non-toxic concentrations can enhance the killing of tumor cells by cytotoxic anti-cancer agents. Genz-123346 and a few other GCS inhibitors are substrates for multi-drug resistance efflux pumps such as P-gp (ABCB1, gP-170). In cell lines selected to over-express P-gp or which endogenously express P-gp, chemosensitization by Genz-123346 was primarily due to the effects on P-gp function. Synonyms: Genz-123346; Genz123346; Genz 123346. CAS No. 491833-30-8. Molecular formula: C24H38N2O4. Mole weight: 418.57. | |
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