BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Hispidol | Hispidol ((Z)-Hispidol) inhibits TNF-α induced adhesion of monocytes to colon epithelial cells (IC50= 0.50 μM) and is a potential therapeutic for inflammatory bowel disease. Synonyms: (2Z)-6-hydroxy-2-[(4-hydroxyphenyl)methylidene]-1-benzofuran-3-one; Hispidol; (Z)-4',6-Dihydroxyaurone; AC1NQYA9; 6,4' -dihydroxy aurone. CAS No. 5786-54-9. Molecular formula: C15H10O4. Mole weight: 254.24. |  |
| Histatin 5 | Histatin 5, a human salivary peptide, has been shown to inhibit the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μM, respectively. Synonyms: H-Asp-Ser-His-Ala-Lys-Arg-His-His-Gly-Tyr-Lys-Arg-Lys-Phe-His-Glu-Lys-His-His-Ser-His-Arg-Gly-Tyr-OH; L-alpha-aspartyl-L-seryl-L-histidyl-L-alanyl-L-lysyl-L-arginyl-L-histidyl-L-histidyl-glycyl-L-tyrosyl-L-lysyl-L-arginyl-L-lysyl-L-phenylalanyl-L-histidyl-L-alpha-glutamyl-L-lysyl-L-histidyl-L-histidyl-L-seryl-L-histidyl-L-arginyl-glycyl-L-tyrosine; Human histatin 5; Peptide F-A (human parotid saliva). Grades: 98%. CAS No. 104339-66-4. Molecular formula: C133H195N51O33. Mole weight: 3036.29. | |
| Histrelin | Histrelin is a nonapeptide analog of GnRH (gonadotropin-releasing hormone) with added potency. When present in the bloodstream, it can act on gonadotropes. Histrelin can stimulate these cells to release luteinizing hormone and follicle-stimulating hormone. Histrelin is considered a GnRH agonist. It can be used for the treatment of menstruation disorders. Uses: Menstruation disorders. Synonyms: Histrelinum; ORF 17070. Grades: 98%. CAS No. 76712-82-8. Molecular formula: C66H86N18O12. Mole weight: 1323.5. | |
| HI TOPK 032 | HI TOPK 032 is a novel TOPK inhibitor as a T-LAK-cell-originated protein kinase (TOPK) inhibitor, blocking phosphorylation of the substrate histone H2AX with an IC50 value of ~2 μM and providing complete inhibition at 5 μM. Uses: A novel topk inhibitor. Synonyms: HI-TOPK-032; HI-TOPK032; HI-TOPK 032. N-(12-Cyanoindolizino[2,3-b]quinoxalin-2-yl)-2-thiophenecarboxamide. Grades: ≥98%. CAS No. 487020-03-1. Molecular formula: C20H11N5OS. Mole weight: 369.4. | |
| HJC0197 | HJC0197 is a erythromycin propionate-N-acetylcysteinate inhibitor (EPAC). IC50 value is 5.9 μM for Epac2. HJC0197 can inhibit Epac1-mediated Rap1-GDP exchange activity at 25 μM, but it has no effect on cAMP-induced type I and II PKA activity at this concentration. HJC0197 can be used to study the role of Epac signaling in chondrogenesis in chicken micromass cultures. EPAC inhibitor may prevent pancreatic cancer cell migration and invasion. Uses: Study the role of epac signaling. Synonyms: HJC0197; HJC-0197; HJC 0197. 4-cyclopentyl-2-((2,5-dimethylbenzyl)thio)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile. Grades: 98%. CAS No. 1383539-73-8. Molecular formula: C19H21N3OS. Mole weight: 339.45. | |
| HL 010183 | HL 010183 is a metformin derivative exhibiting potent antitumor effect. It inhibits proliferation and invasion of Hs578T triple-negative (TN) breast cancer cells. Uses: Antitumor agent. Synonyms: HL 010183; HL010183; HL-010183. Grades: 99%. CAS No. 1429218-03-0. Molecular formula: C14H20N6.HCl. Mole weight: 308.81. | |
| HLCL65 hydrochloride | HLCL65 hydrochloride is a first-in-class inhibitor of PRMT5. HLCL65 selectively inhibits Th1 cell proliferation (IC50 value 1.1 μM). In vivo, HLCL65 suppresses recall T cell responses and reduces inflammation in delayed-type hypersensitivity and clinical disease in experimental autoimmune encephalomyelitis mouse models; In vitro, HLCL65 effectively inhibits symmetric arginine dimethylation (me2) of histones H3 and H4 in AML samples. Synonyms: HLCL65 hydrochloride; HLCL 65 hydrochloride; HLCL-65 hydrochloride; 1-(6-bromo-9-ethylcarbazol-3-yl)-N-[(2-methoxyphenyl)methyl]methanamine hydrochloride. Grades: 99%. Molecular formula: C23H23BrN2O.HCl. Mole weight: 459.81. | |
| HM-30181 hydrochloride | HM30181 is a P-glycoprotein (P-gp) inhibitor developed to enhance the oral bioavailability of P-gp substrate drugs. HM30181 showed the highest potency among several MDR1 inhibitors with IC50 value of 0.63nM. HM30181 is currently under Phase I trials. Uses: Enhance the oral bioavailability of p-gp substrate drugs. Synonyms: HM-30181 hydrochloride; HM 30181 hydrochloride; HM30181 hydrochloride; N-(2-(2-(4-(2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)-2H-tetrazol-5-yl)-4,5-dimethoxyphenyl)-4-oxo-4H-chromene-2-carboxamide hydrochloride. Grades: 98%. CAS No. 849675-88-3. Molecular formula: C38H37ClN6O7. Mole weight: 725.20. | |
| HM-30181 mesylate | HM30181 is a P-glycoprotein (P-gp) inhibitor developed to enhance the oral bioavailability of P-gp substrate drugs. HM30181 showed the highest potency among several MDR1 inhibitors with IC50 value of 0.63nM. HM30181 is currently under Phase I trials. Uses: Enhance the oral bioavailability of p-gp substrate drugs. Synonyms: HM-30181 mesylate; HM 30181 mesylate; HM30181 mesylate; N-(2-(2-(4-(2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)-2H-tetrazol-5-yl)-4,5-dimethoxyphenyl)-4-oxo-4H-chromene-2-carboxamide methanesulfonate;849675-88-3 (HM30181 HCl salt);49675-66-7 (HM30181 Free base). Grades: 98%. CAS No. 849675-87-2. Molecular formula: C39H40N6O10S. Mole weight: 784.84. | |
| HM 50316 | HM 50316 is a high affinity fatty-acid binding protein 4 (FABP4) inhibitor (Ki < 1 nM) that selectively inhibits FABP4 over FABP3. It inhibits LPS-induced activation of murine macrophages in vitro. HM 50316 may be beneficial for the treatment of atherosclerosis, type 2 diabetes and other inflammatory and metabolic related diseases. Synonyms: HM-50316; HM 50316; HM50316. 2-[[2'-[1-(4-Chlorophenyl)-5-(2-thienyl)-1H-pyrazol-3-yl][1,1'-biphenyl]-3-yl]oxy]-2-methylpropanoic acid. Grades: ≥98% by HPLC. CAS No. 1310361-52-4. Molecular formula: C29H23ClN2O3S. Mole weight: 515.02. | |
| HMHA-Gln | Synonyms: HMHA Gln; Nα-3-methyl-3-hydroxy-hexanoyl-glutamine. Molecular formula: C12H22N2O5. Mole weight: 274.31. | |
| HMN-154 | HMN-154, a novel benzenesulfonamide anticancer drug, inhibits KB (IC50= 0.0026 μg/mL) and colon38 cells (IC50= 0.003 μg/mL). Synonyms: 4-methoxy-N-[2-[(E)-2-pyridin-4-ylethenyl]phenyl]benzenesulfonamide; (E)-4-(2-(2-p-methoxy-benzene-sulfonamide) phenyl)(ethenyl ) pyridine; HMN-154; HMN 154; HMN154. CAS No. 173528-92-2. Molecular formula: C20H18N2O3S. Mole weight: 366.43. | |
| HMR 1031 | HMR 1031 is a potent and specific integrin α4β1 or very late antigen 4 (VLA-4) receptor antagonist binding to vascular cell adhesion molecule-1 (VCAM-1) and fibronectin. HMR1031 has the potential used as an inhaled drug for the treatment of asthma. Uses: Potential inhaled drug for asthma. Synonyms: HMR-1031; HMR 1031; HMR1031; Rnm7wqo98Y; (3S) -3-[[ (2S) -2-[4, 4-dimethyl-3-[[4-[ (2-methylphenyl) carbamoylamino]phenyl]methyl]-2, 5-dioxoimidazolidin-1-yl]-4-methylpentanoyl]amino]-3-phenylpropanoic acid. Grades: 98%. CAS No. 479203-71-9. Molecular formula: C35H41N5O6. Mole weight: 627.73. | |
| HMR 1556 | HMR 1556 is a potent and selective Iks channel blocker (IC50 = 10.5 and 34 nM in canine and guinea pig ventricular myocytes, respectively). It selectively inhibits IKs currents over IKr, IKI, Ito and L-type Ca2+ channel currents. HMR 1556 also exhibits weak activity at Kv11.1 Kv1.5, Kv1.3, Kir2.1 and HCN2 channel currents. HMR 1556 is used in the treatment of proarrythmia. Uses: The treatment of proarrythmia. Synonyms: HMR-1556; HMR 1556; HMR1556.N-[(3R,4S)-3,4-Dihydro-3-hydroxy-2,2-dimethyl-6-(4,4,4-trifluorobutoxy)-2H-1-benzopyran-4-yl]-N-methylmetanesulfonamide. Grades: ≥98% by HPLC. CAS No. 223749-46-0. Molecular formula: C17H24F3NO5S. Mole weight: 411.44. | |
| HNGF6A | HNGF6A is a humanin analog that increases glucose stimulated insulin secretion and glucose metabolism in vivo and in vitro. HNGF6A enhances glucose sensing in βTC3 cells and decreases blood glucose level in Zucker diabetic fatty rats. HNGF6A is used for the prevention of endothelial dysfunction and atherosclerosis in vivo. Uses: The prevention of endothelial dysfunction and atherosclerosis. Synonyms: HNGF6A; 1093111-54-6; AKOS024458518; PD079802. CAS No. 1093111-54-6. Molecular formula: C112H198N34O31S2. Mole weight: 2581.13. | |
| (-)-Holostyligone | (-)-Holostyligone is a lignan isolated from the Holostylis reniformis. Synonyms: (2S,3S,4R)-4-(4-hydroxy-3-methoxyphenyl)-6,7-dimethoxy-2,3-dimethyl-3,4-dihydro-2H-naphthalen-1-one. Grades: >98%. CAS No. 887501-28-2. Molecular formula: C21H24O5. Mole weight: 356.418. | |
| Homoalanosine | Homoalanosine is an amino acid analogue and a derivative of alanosine, an antibiotic used in the treatment of pancreatic cancer. Grades: 98%. CAS No. 114707-36-7. Molecular formula: C4H9N3O4. Mole weight: 163.13. | |
| Homoplantaginin | Homoplantaginin is a flavonoid glycoside found in Scoparia dulcis. Homoplantaginin ameliorates endothelial insulin resistance by inhibiting inflammation and modulating cell signalling via the IKKβ/IRS-1/pAkt/peNOS pathway, suggesting it may be used for the prevention and treatment of endothelial dysfunction associated with insulin resistance. Synonyms: 5-hydroxy-2-(4-hydroxyphenyl)-6-methoxy-4-oxo-4H-chromen-7-yl beta-D-glucopyranoside. Grades: >98%. CAS No. 17680-84-1. Molecular formula: C22H22O11. Mole weight: 462.4. | |
| Homo-PROTAC cereblon degrader 1 | Homo-PROTAC cereblon degrader 1 (compound 15a) is a highly potent and efficient cereblon (CRBN) degrader with only minimal effects on IKZF1 and IKZF3. Synonyms: 2- (2, 6-dioxopiperidin-3-yl) -4- [2- [2- [2- [ [2- (2, 6-dioxopiperidin-3-yl) -1, 3-dioxoisoindol-4-yl] amino] ethoxy] ethoxy] ethylamino] isoindole-1, 3-dione. CAS No. 2244520-98-5. Molecular formula: C32H32N6O10. Mole weight: 660.63. | |
| Homosalate | Homosalate could be commonly useful in sorts of cosmetics acting as a chemical UV filter. Uses: Homosalate could be commonly useful in sorts of cosmetics acting as a chemical uv filter. Synonyms: SALICYLIC ACID 3,3,5-TRIMETHYLCYCLOHEXYL ESTER;trimethylcyclohenyl salicylate;Benzoic acid, 2-hydroxy-, 3,3,5-trimethylcyclohexyl ester;Benzoicacid,2-hydroxy-,3,3,5-trimethylcyclohexylester;component of Coppertone;Coppertone;Filtersol ''A'';Filtrosol A. Grades: 98%. CAS No. 118-56-9. Molecular formula: C16H22O3. Mole weight: 262.35. | |
| Hoquizil hydrochloride | Hoquizil hydrochloride is a new oral bronchodilator. Synonyms: (2-hydroxy-2-methylpropyl) 4-(6,7-dimethoxyquinazolin-4-yl)piperazine-1-carboxylate;hydrochloride; Hoquizil hydrochloride; Hoquizil HCl; CP-14,185-1; CP-14185-1. Grades: >98%. CAS No. 23256-28-2. Molecular formula: C19H27ClN4O5. Mole weight: 426.89. | |
| Horseradish peroxidase | Peroxidase is a heme-containing enzyme, and it can be used to oxidize a wide variety of substrates. Synonyms: HRP; Peroxidase. CAS No. 9003-99-0. Molecular formula: H2O3. | |
| Hosenkoside C | Hosenkoside C is a triterpenoid compound found in the Impatiens balsamina L. Synonyms: HosenkosideC; Hosenkoside C; 156764-83-9; HY-N2251; AKOS037515120; AC-34211; CS-0019576. Grades: >98%. CAS No. 156764-83-9. Molecular formula: C48H82O20. Mole weight: 979.164. | |
| Hosenkoside F | Hosenkoside F is a triterpenoid compound found in the Impatiens balsamina L. Synonyms: Hosenkoside F; 160896-45-7; HosenkosideF; HY-N2241; AKOS037515121; MS-31775; CS-0019564; Hosenkoside F (Synonyms: (+)-Hosenkoside F). Grades: >98%. CAS No. 160896-45-7. Molecular formula: C47H80O19. Mole weight: 949.138. | |
| Hosenkoside G | Hosenkoside G is a triterpenoid compound found in the Impatiens balsamina L. Grades: >98%. CAS No. 160896-46-8. Molecular formula: C47H80O19. Mole weight: 949.138. | |
| Hosenkoside M | Hosenkoside M is a triterpenoid compound found in the Impatiens balsamina L. Synonyms: Hosenkoside M; 161016-51-9; (+)-HosenkosideM; (+)-Hosenkoside M; HY-N2244; AKOS037515123; MS-31975; CS-0019567; Hosenkoside M (Synonyms: (+)-Hosenkoside M). Grades: >98%. CAS No. 161016-51-9. Molecular formula: C53H90O24. Mole weight: 1111.279. | |
| H-Phe(4-Ac)-OH HCl | H-Phe(4-Ac)-OH HCl, an essential chemical for a wide range of pharmaceutical and peptide synthesis, boasts exceptional adequacy as a constituent for drug production. This product serves as a key reagent as well as a fundamental building block in the synthesis of peptide-based medications. Medical professionals and researchers commonly employ H-Phe(4-Ac)-OH HCl as an effective measure in the treatment of chronic pain and inflammation arising due to a multitude of conditions, including but not limited to osteoarthritis and rheumatoid arthritis. Synonyms: 4-Acetyl-L-phenylalanine Hydrochloride; 4-Acetylphenylalanine hydrochloride; (S)-3-(4-Acetylphenyl)-2-aminopropanoic acid HCl; p-Acetylphenylalanine hydrochloride. CAS No. 20299-31-4. Molecular formula: C11H14ClNO3. Mole weight: 243.68. | |
| HQ-415 | HQ-415 is a relevant bioactive metal chelators(EC50=15 μM). Uses: A relevant bioactive metal chelators. Synonyms: 7-[(3-Ethoxy-4-methoxyphenyl)-[(4-methylpyridin-2-yl)amino]methyl]quinolin-8-ol; HQ-415; HQ 415; HQ415. Grades: ≥95%. CAS No. 430462-93-4. Molecular formula: C25H25N3O3. Mole weight: 415.48. | |
| HQL 79 | HQL 79 is a selective inhibitor of human hematopoietic prostaglandin D synthase (H-PGDS) (IC50 = 6 μM). HQL 79 is potentially used as an antihistamine that exerts antiallergic and antiasthmatic properties in vivo. Synonyms: HQL-79; HQL 79; HQL79. 4-(Diphenylmethoxy)-1-(3-2H-tetrazol-5-yl)propyl]-piperidine; Cc-704. Grades: ≥99% by HPLC. CAS No. 162641-16-9. Molecular formula: C22H27N5O. Mole weight: 377.48. | |
| HS-1371 | HS-1371 is a novel RIP3 kinase inhibitor with IC50 value of 20.8 nM. It binds to RIP3 in an ATP-competitive and time-independent manner in vitro, and inhibits RIP3-mediated necroptosis via the suppression of RIP3 kinase activity. Synonyms: HS 1371; HS1371; 4-(4-Methylphenoxy)-7-(1-piperidin-4-ylpyrazol-4-yl)quinoline. CAS No. 2158197-70-5. Molecular formula: C24H24N4O. Mole weight: 384.47. | |
| HSF1B | HSF1B is a human heat shock factor protein (HSF1) activator. Synonyms: N-[2,5-bis(4-chlorophenyl)pyrazol-3-yl]-4-butylbenzamide. Grades: 99%. CAS No. 1196723-95-1. Molecular formula: C26H23Cl2N3O. Mole weight: 464.39. | |
| HSR6071 | HSR60716071, a novel pyrazinecarboxamide derivative, exhibits potent inhibition of the IgE-mediated passive cutaneous anaphylaxis (PCA) in rats on oral administration, and that its inhibition of PCA is at least in part due to the depression of allergic histamine release from mast cells. Synonyms: 6-pyrrolidin-1-yl-N-(2H-tetrazol-5-yl)pyrazine-2-carboxamide; 6-(1-pyrrolidinyl)-N-(1H-tetrazol-5-yl)-2-pyrazinecarboxamide; HSR 6071l; HSR-6071. CAS No. 111374-21-1. Molecular formula: C10H12N8O. Mole weight: 260.26. | |
| HTS01037 | HTS01037, a high-affinity ligand of adipocyte fatty acid binding protein (A-FABP/aP2) (Ki = 0.67 μM), and is a competitive antagonist of protein-protein interactions mediated by AFABP/aP2 (Ki= 0.67 μM). Synonyms: HTS01037; HTS 01037; HTS-01037. 4-[(2-methoxycarbonyl-5-thiophen-2-ylthiophen-3-yl)amino]-4-oxobut-2-enoic acid; (E)-4-[(2-methoxycarbonyl-5-thiophen-2-ylthiophen-3-yl)amino]-4-oxobut-2-enoic acid; 4-{[2-(methoxycarbonyl)-5-(2-thienyl)-3-thienyl]amino}-4-oxo-2-butenoic acid. CAS No. 682741-29-3. Molecular formula: C14H11NO5S2. Mole weight: 337.37. | |
| HUHS015 | HUHS015 is a potent PCA-1/ALKBH3 inhibitor both in vitro and in vivo. The bioavailability (BA) of HUHS015 was 7.2% in rats after oral administration. As expected, continuously administering HUHS015 significantly suppressed the growth of DU145 cells, which are human hormone-independent prostate cancer cells, in a mouse xenograft model without untoward effects. Synonyms: HUHS015; HUHS 015; HUHS-015. Grades: 0.98. CAS No. 1453097-13-6. Molecular formula: C19H18N4O. Mole weight: 318.37242. | |
| Human neutrophil peptide-1 | Human neutrophil peptide-1 is an antimicrobial peptide found in Homo sapiens (Human). It belongs to the alpha-defensin family and has antimicrobial activity against gram-negative bacteria, gram-positive bacteria and Fungi. Synonyms: H-Ala-Cys(1)-Tyr-Cys(2)-Arg-Ile-Pro-Ala-Cys(3)-Ile-Ala-Gly-Glu-Arg-Arg-Tyr-Gly-Thr-Cys(2)-Ile-Tyr-Gln-Gly-Arg-Leu-Trp-Ala-Phe-Cys(3)-Cys(1)-OH; L-alanyl-L-cysteinyl-L-tyrosyl-L-cysteinyl-L-arginyl-L-isoleucyl-L-prolyl-L-alanyl-L-cysteinyl-L-isoleucyl-L-alanyl-glycyl-L-alpha-glutamyl-L-arginyl-L-arginyl-L-tyrosyl-glycyl-L-threonyl-L-cysteinyl-L-isoleucyl-L-tyrosyl-L-glutaminyl-glycyl-L-arginyl-L-leucyl-L-tryptophyl-L-alanyl-L-phenylalanyl-L-cysteinyl-L-cysteine (2->30),(4->19),(9->29)-tris(disulfide); Human Defensin NP-1; alpha-Defensin-1; Defensin HNP-1 (human); HNP-1; Defensin human neutrophil peptide-1. Grades: >95%. CAS No. 99287-08-8. Molecular formula: C150H222N44O38S6. Mole weight: 3442.03. | |
| Hupehemonoside | Hupehemonoside is found in Fritillaria pallidiflora. Synonyms: Imperialine 3-beta-D-glucoside; Sipeimine-3-β-D-glucoside. Grades: > 95%. CAS No. 67968-40-5. Molecular formula: C33H53NO8. Mole weight: 591.77. | |
| Hupehenine | Hupehenine is isolated from Fritillaria thunbergii Miq. Synonyms: Cevane-3, 6-diol(3β, 5α, 6β, 17β). Grades: >98%. CAS No. 98243-57-3. Molecular formula: C27H45NO2. Mole weight: 415.65. | |
| Hybendazole hydrochloride | Hybendazole hydrochloride is a synthetic bio-active chemical. Uses: A synthetic bio-active chemical. Synonyms: Hybendazole hydrochloride; Hybendazole HCl; AT-1921; AT 1921; AT1921. DL-2-(alpha-Hydroxybenzyl)benzimidazole hydrochloride. Grades: ≥98%. CAS No. 37975-24-9. Molecular formula: C14H13ClN2O. Mole weight: 260.72. | |
| hydracarbazine | Hydracarbazine is a pyridazine that may increase the hypertensive activities of Acebutolol. Uses: An antihypertensive agent. Synonyms: TH 2151; TH-2151; TH2151; 6-hydrazinylpyridazine-3-carboxamide. Grades: ≥98%. CAS No. 3614-47-9. Molecular formula: C5H7N5O. Mole weight: 153.144. | |
| Hydrastinine hydrochloride | Hydrastinine hydrochloride is a semisynthetic alkaloid as a haemostatic drug. Uses: Semisynthetic alkaloid. Synonyms: 6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-ol;hydrochloride. Grades: ≥98%. CAS No. 4884-68-8. Molecular formula: C11H14ClNO3. Mole weight: 243.69. | |
| Hydrocortamate hydrochloride | This active molecular is a synthetic glucocorticoid with immunosuppressive and anti-inflammatory properties. Hydrocortamate hydrochloride is applicated for the treatment of inflammation caused by corticosteroid-responsive dermatoses. Uses: Inflammation. Synonyms: UNII-9QM8U7R83W; EINECS 204-723-4;Ethamicort; Ulcort; Magnacort; Hydrocortamate HCl; [2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 2-(diethylamino)acetate; hydrochloride; 76-47-1( free base). Grades: 98%. CAS No. 125-03-1. Molecular formula: C27H42ClNO6. Mole weight: 512.08. | |
| Hydrocortisone aceponate | Hydrocortisone aceponate is a corticosteroid used in form of creams for the treatment of various dermatoses (skin conditions). Synonyms: Efficort. Grades: 95%. CAS No. 74050-20-7. Molecular formula: C26H36O7. Mole weight: 460.563. | |
| Hydrocortisone phosphate | Hydrocortisone is a corticosteroid increases blood sugar through gluconeogenesis to suppress the immune system. Uses: A steroid hormone, in the glucocorticoid class of hormones. Synonyms: 1β,17,21-trihydroxypregn-4-ene-3,20-dione 21-(dihydrogen phosphate); Cortisol 21-phosphate; (11beta)-11,17-Dihydroxy-3,20-dioxopregn-4-en-21-yl dihydrogen phosphate. Grades: ≥98%. CAS No. 3863-59-0. Molecular formula: C21H31O8P. Mole weight: 442.44. | |
| Hydroxy Adapalene | Hydroxy Adapalene is an impurity of a third-generation topical retinoid Adapalene, which is commonly used to treat skin conditions such as acne and keratosis pilaris. Synonyms: Adapalene EP Impurity B; 6-(3-(3-Hydroxytricyclo(3.3.1.13,7)dec-1-yl)-4-methoxyphenyl)naphthalene-2-carboxylic acid. Grades: >95%. CAS No. 1346599-76-5. Molecular formula: C28H28O4. Mole weight: 428.53. | |
| Hydroxy-alpha-sanshool | Hydroxy-alpha-sanshool is a compound isolated from the genus Zanthoxylum. It stimulates D-hair afferent nerve fibers. Synonyms: (2E,6Z,8E,10E)-N-(2-Hydroxy-2-methylpropyl)-2,6,8,10-dodecatetraenamide. CAS No. 83883-10-7. Molecular formula: C16H25NO2. Mole weight: 263.381. | |
| Hydroxy-beta-sanshool | Hydroxy-beta-sanshool is a compound isolated from the genus Zanthoxylum. Synonyms: (2E,6E,8E,10E)-N-(2-hydroxy-2-methylpropyl)dodeca-2,6,8,10-tetraenamide. CAS No. 97465-69-5. Molecular formula: C16H25NO2. Mole weight: 263.381. | |
| Hydroxy Brimonidine | Hydroxy Brimonidine is an impurity of Brimonidine, a medication used to lower pressure in the eyes in patients who have glaucoma. Synonyms: Brimonidine EP Impurity G. Grades: 95%. CAS No. 1216379-05-3. Molecular formula: C11H12BrN5O. Mole weight: 310.15. | |
| Hydroxybupropion | Hydroxybupropion is a primary metabolite of bupropion. Bupropion is a pharmaceutical used as an antidepressant and a smoking cessation drug sold under the trade names Wellbutrin® and Zyban®. Synonyms: HYDROXYBUPROPION; HYDROXYBUPROPIONE; 1-(3-CHLOROOPHENYL)-2-[(2-HYDROXY-1,1-DIMETHYLETHYL)AMINO]-1-PROPANONE; 2-HYDROXY-2-(3'-CHLOROPHENYL)-3,5,5-TRIMETHYLMORPHOLINE; 1-(3-Chloroophenyl)-2-[(2-hydroxy-1,1-dimethylethyl)amino]-1-propanone, 2-Hydroxy-2-(3chlorop. Grades: > 95%. CAS No. 92264-81-8. Molecular formula: C13H18ClNO2. Mole weight: 255.75. | |
| Hydroxychloroquine | Hydroxychloroquine is a synthetic antimalarial agent and it can inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine efficiently inhibits SARS-CoV-2 infection in vitro. Uses: Antimalarials. Synonyms: Plaquenil; Oxichloroquine; Polirreumin; 7-Chloro-4-(4-(ethyl(2-hydroxyethyl)amino)-1-methylbutylamino)quinoline; WIN 1258; Win 1258-2. Grades: ≥97%. CAS No. 118-42-3. Molecular formula: C18H26ClN3O. Mole weight: 335.87. | |
| Hydroxychloroquine Sulfate | Hydroxychloroquine Sulfate is an autophagy inhibitor that induces autophagic cell death. It also inhibits TLR9. Hydroxychloroquine is an antimalarial drug, and in combination with other medications, it can be used in the treatment of some autto-immune diseases. It has been used in emergency of COVID-19. Synonyms: 2-[[4-[ (7-Chloro-4-quinolinyl) amino]pentyl]ethylamino]ethanol sulfate. Grades: > 95%. CAS No. 747-36-4. Molecular formula: C18H28ClN3O5S. Mole weight: 433.95. | |
| Hydroxydichlorodiphenyl ether | Hydroxydichlorodiphenyl ether, a chemical compound employed as a fungicide and pesticide, exhibits the capacity to halt the proliferation of cancer cells, thereby displaying promise in therapeutic applications against leukemia and breast cancer. Notably, the compound also showcases clinical relevance in treating skin conditions such as psoriasis and eczema. The multifaceted properties exhibited by Hydroxydichlorodiphenyl ether offer a broad spectrum of potential clinical applications. Synonyms: 2-Hydroxy-4,4'-dichlordiphenyl ether; Phenol, 5-chloro-2-(4-chlorophenoxy)-; 2-Hydroxy-4,4'-dichlorodiphenyl ether. CAS No. 3380-30-1. Molecular formula: C12H8Cl2O2. Mole weight: 255.10. | |
| Hydroxy Donepezil | An impurity of Donepezil, a medication for the treatment of Alzheimer's disease. Synonyms: 2,3-Dihydro-2-[hydroxy[1-(phenylmethyl)-4-piperidinyl]methyl]-5,6-dimethoxy-1H-inden-1-one; 2-[(1-Benzylpiperidin-4-yl)hydroxymethyl]-5,6-dimethoxyindan-1-one. Grades: > 95%. CAS No. 197010-20-1. Molecular formula: C24H29NO4. Mole weight: 395.5. | |
| Hydroxyfasudil Hydrochloride | Hydroxyfasudil Hydrochloride, an active metabolite of Fasudil, preferentially inhibits Rho-kinase and plays a central role in the pathogenesis of coronary artery spasm. It is reported to inhibit neutrophil migration and exhibit potent vasodilatory effects in vivo. Synonyms: HA 1100 hydrochloride; HA1100 hydrochloride; HA-1100 hydrochloride; 5-(1,4-diazepan-1-ylsulfonyl)-2~{H}-isoquinolin-1-one hydrochloride; 1-[(1,2-Dihydro-1-oxo-5-isoquinolinyl)sulfonyl]hexahydro-1H-1,4-diazepine hydrochloride. Grades: >98%. CAS No. 155558-32-0. Molecular formula: C14H18ClN3O3S. Mole weight: 343.826. | |
| Hydroxy-γ-sanshool | Hydroxy-γ-sanshool is an alkaloid isolated from Zanthoxylum bungeanum Maxim. Synonyms: Hydroxy-gamma-Sanshool. Grades: 98%. CAS No. 78886-66-5. Molecular formula: CFN91157. Mole weight: 289.4. | |
| Hydroxyhexamide | Hydroxyhexamide, a derivative of acetohexamide, obtained as a pharmacologically active metabolite of acetohexamide. It might be used in the treatment of type 2 diabetes as a Hypoglycemic agent. Uses: Hydroxyhexamide is a pharmacologically active metabolite of acetohexamide and could be used as a hypoglycemic agent against type 2 diabetes. Synonyms: HYDROXYHEXAMIDE; AC1L2C6O; CHEMBL2105052; HY-B1103. Grades: ≥ 95%. CAS No. 3168-1-2. Molecular formula: C15H22N2O4S. Mole weight: 326.41. | |
| hydroxy-[hydroxy(dimethyl)silyl]oxy-dimethylsilane | Synonyms: 1,1,3,3-Tetramethyldisiloxane-1,3-diol; 1,3-Dihydroxy-1,1,3,3-tetramethyl-1,3-disiloxane; 1,3-Dihydroxy-1,1,3,3-tetramethyldisiloxane; 1,3-Dihydroxytetramethyldisiloxane; Tetramethyldisiloxane-1,3-diol; Tetramethyldisiloxanediol; 1,1,3,3-Tetramethyl-1,3-disiloxanediol; 1,1,3,3-Tetramethyl-1,3-dihydroxydisiloxane; Tetramethyl-1,3-disiloxanediol. Grades: 95%. CAS No. 1118-15-6. Molecular formula: C4H14O3Si2. Mole weight: 166.32. | |
| Hydroxy Itraconazole | A metabolite of Itraconazole, an orally active antimycotic structurally related to Ketoconazole. Uses: Hydroxy itraconazole is a metabolite of itraconazole and could be used as an antimycotic. Synonyms: 4-[4-[4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(2-hydroxy-1-methylpropyl)-3H-1,2,4-triazol-3-one. Grades: > 95%. CAS No. 112559-91-8. Molecular formula: C35H38Cl2N8O5. Mole weight: 721.65. | |
| Hydroxymethyl EDOT | Hydroxymethyl EDOT (CAS# 146796-02-3 ) is a useful research chemical. Synonyms: (2,3-Dihydrothieno[3,4-b][1,4]dioxin-2-yl)methanol; EDT-methanol. Grades: 95 %. CAS No. 146796-02-3. Molecular formula: C7H8O3S. Mole weight: 172.20. | |
| Hyoscyamine Sulfate | Cas No. 6835-16-1. | |
| Hypaconine | Hypaconine, a naturally occurring alkaloid, has been extensively researched for its potential use as an agent for combating cancer. Several studies have revealed that Hypaconine effectively suppresses the proliferation of select cancer cells, thereby demonstrating its potential as a therapeutic intervention for cancer treatment. Furthermore, Hypaconine's properties have also drawn interest as a possible neuroprotective agent. The versatility of this compound, therefore, offers promising therapeutic applications in the treatment of neurodegenerative ailments. Synonyms: Benzoylhypacoitine; (1alpha, 6alpha, 14alpha, 15alpha, 16beta)-1, 6, 16-Trimethoxy-4-(methoxymethyl)-20-methylaconitane-8, 13, 14, 15-tetrol; 3-Deoxymesaconine. Grades: >98%. CAS No. 63238-68-6. Molecular formula: C24H39NO8. Mole weight: 469.6. | |
| Hyponine D | Hyponine D is a sesquiterpene alkaloid. Synonyms: Hyponine D; 259823-31-9; hyponin DCHEMBL504037CHEBI:132388. Grades: >98%. CAS No. 259823-31-9. Molecular formula: C47H50N2O18. Mole weight: 930.913. | |
| Hyponine E | Hyponine E is a sesquiterpene alkaloid isolated from Tripterygium hypoglaucum. Synonyms: (-)-Hyponine E. Grades: >98%. CAS No. 226975-99-1. Molecular formula: C45H48N2O19. Mole weight: 920.874. | |
| Hythiemoside B | Hythiemoside B is found in Siegesbeckia orientalis. Synonyms: Hythiemoside B; 853267-90-0; HY-N8150; CS-0140208E87124. Grades: > 95%. CAS No. 853267-90-0. Molecular formula: C28H46O9. Mole weight: 526.66. | |
| Ibandronate Sodium | Ibandronate sodium is a potent bisphosphonate drug developed by Hoffman La Roche and used in the prevention and treatment of osteoporosis and metastasis-associated skeletal fractures in people with cancer. It may also be used to treat hypercalcemia (elevated blood calcium levels). Ibandronate is indicated for the treatment and prevention of osteoporosis in post-menopausal women. In May 2003, the U.S. Food and Drug Administration (FDA) approved Ibandronate as a daily treatment for post-menopausal osteoporosis. Ibandronate is efficacious for the prevention of metastasis-related bone fractures in multiple myeloma, breast cancer, and certain other cancers. Uses: Bone density conservation agents. Synonyms: Boniva Sodium; Bondronat Sodium; Bonviva Sodium. Grades: >98%. CAS No. 138844-81-2. Molecular formula: C9H22NNaO7P2. Mole weight: 341.21. | |
| Iberdomide | Iberdomide (CC-220) is a cereblon modulator with an IC50 of 60 nM. It has antitumor and immunomodulatory activities. Synonyms: (3S)-3-[7-[[4-(morpholin-4-ylmethyl)phenyl]methoxy]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione; CC-220; CC220; CC 220; Iberdomide. CAS No. 1323403-33-3. Molecular formula: C25H27N3O5. Mole weight: 449.5. | |
| Iberin | Iberin, a naturally occurring member of isothiocyanate family found in cruciferous plants, inhibits cell survival (IC50 = 2.3 μM in HL60 cell). Synonyms: 1-isothiocyanato-3-methylsulfinylpropane; 1-isothiocyanato-3-(methylsulfinyl)propane; 1-isothiocyanato-3-(methylsulphinyl)propane; iberin; IMSP. CAS No. 505-44-2. Molecular formula: C5H9NOS2. Mole weight: 163.26. | |
| I-BET151 | I-BET151 is a BET bromodomain inhibitor, which blocks recruitment of BET to chromatin. It was shown to induce early cell cycle arrest and apoptosis in human and mouse MLL-fusion leukemia cell lines. Synonyms: GSK1210151A; 7-(3,5-Dimethyl-4-isoxazolyl)-1,3-dihydro-8-methoxy-1-[(1R)-1-(2-pyridinyl)ethyl]-2H-imidazo[4,5-c]quinolin-2-one. Grades: >98%. CAS No. 1300031-49-5. Molecular formula: C23H21N5O3. Mole weight: 415.453. | |
| I-BET762 carboxylic acid | I-BET762 carboxylic acid is an I-BET762-based warhead ligand for conjugation reactions of PROTAC targeting on BET. I-BET762 carboxylic acid (Molibresib carboxylic acid) is a BRD4 inhibitor with a pIC50 of 5.1. Synonyms: Molibresib carboxylic acid; GSK525762A carboxylic acid; PROTAC BRD4-binding moiety 2. CAS No. 1300019-38-8. Molecular formula: C20H17ClN4O3. Mole weight: 396.83. | |
| Ibodutant | Ibodutant is a tachykinin receptor antagonist. It selectively blocks the tachykinin receptor NK2, with blockade practically complete in nanomolar concentrations. It is a candidate drug for irritable bowel syndrome diarrhea. It was developed by The Menarini Group. It is in the clinical phase III. Uses: Ibodutant is a candidate drug for irritable bowel syndrome diarrhea. Synonyms: MEN-15596; MEN 15596; MEN15596; Ibodutant 6-Methyl-N-[1-[[(2R)-1-[[1-(oxan-4-ylmethyl)piperidin-4-yl]methylamino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]cyclopentyl]-1-benzothiophene-2-carboxamide;(R)-6-methyl-N-(1-((1-oxo-3-phenyl-1-(((1-((tetrahydro-2H-pyran-4-yl)methyl)piperidi. Grades: 98%. CAS No. 522664-63-7. Molecular formula: C37H48N4O4S. Mole weight: 644.87. | |
| I-BOP | I-BOP is a potent TP receptor agonist that induces platelet aggregation and vascular smooth muscle contraction. Synonyms: (Z)-7-[(1S,2R,3R,4R)-3-[(E,3R)-3-hydroxy-4-(4-iodophenoxy)but-1-enyl]-7-oxabicyclo[2.2.1]heptan-2-yl]hept-5-enoic acid. Grades: ≥95%. CAS No. 128719-90-4. Molecular formula: C23H29IO5. Mole weight: 512.4. | |
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