BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Gusperimus trihydrochloride | Gusperimus is a derivative of the anti-tumor antibiotic spergualin, which has immunosuppressive activity. Synonyms: Spanidin; NKT-01. Grades: 98%. CAS No. 85468-01-5. Molecular formula: C17H37N7O3.3HCl. Mole weight: 496.91. |  |
| GW-3333 | GW-3333 is a dual inhibitors of tumor necrosis factor-alpha (TNF)-Converting Enzyme (TACE) and matrix metalloproteinases. Synonyms: GW-3333; GW3333; GW 3333; 3-[formyl(hydroxy)amino]-4-methyl-N-[3-methyl-1-oxo-1-(pyridin-2-ylamino)pentan-2-yl]-2-(2-methylpropyl)pentanamide. Grades: >98%. CAS No. 212609-68-2. Molecular formula: C22H36N4O4. Mole weight: 420.55. | |
| GW 441756 | GW 441756 is a potent and selective Tropomyosin-related kinase A (TrkA) inhibitor (IC50 = 2 nM), reducing cell proliferation and potentiates the effects of chemotherapeutic agents. Uses: A specific tropomyosin-related kinase a (trka) inhibitor. Synonyms: GW-441756; GW 441756; GW441756. 1,3-Dihydro-3-[(1-methyl-1H-indol-3-yl)methylene]-2H-pyrrolo[3,2-b]pyridin-2-one;(3Z)-3-[(1-methylindol-3-yl)methylidene]-1H-pyrrolo[3,2-b]pyridin-2-one. Grades: ≥98%. CAS No. 504433-23-2. Molecular formula: C17H13N3O. Mole weight: 275.30. | |
| GW-6604 | GW6604 is a potent and selective ALK-5 inhibitor with an IC(50) of 140 nM and in a cellular assay inhibited TGF-beta-induced transcription of PAI-1 (IC(50): 500 nM). In vivo, GW6604 (40 mg kg(-1) p.o.) increased liver regeneration in TGF-beta-overexpressing mice, which had undergone partial hepatectomy. Uses: Alk-5 inhibitor. Synonyms: GW6604; GW-6604; GW 6604. 2-phenyl-4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridine. Grades: ≥98%. CAS No. 452342-37-9. Molecular formula: C19H14N4. Mole weight: 298.34. | |
| GW 803430 | GW 803430 is a potent and selective melanin-concentrating hormone receptor 1 (MCH1) antagonist (IC50 = 9.3 nM). GW 803430 exhibits antiobesity and antidepressant-like effects in rats and mice. Synonyms: GW-803430; GW 803430; GW803430. 6-(4-Chlorophenyl)-3-[3-methoxy-4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-thieno[3,2-d]pyrimidin-4(3H)-one. Grades: ≥99% by HPLC. CAS No. 515141-51-2. Molecular formula: C25H24ClN3O3S. Mole weight: 481.99. | |
| GW-870086 | GW-870086 is a glucocorticoid receptor agonist with a pIC50 of 10.1 in A549 cells expressing NF-κB. It can be used as an anti-inflammatory agent. Synonyms: GW-870086; GW-870086X; 870086; GW870086; GW870086X; GW 870086; GW 870086X. CAS No. 827319-43-7. Molecular formula: C31H39F2NO6. Mole weight: 559.651. | |
| Gyki 13324 | GYKI-13324 is bifunctional nitrosoureido derivative and alkylating agent. It can produce long-term or total regression of adenomatous, but only marginal growth delay of mucinous tumors. GYKI-13324, seems to be a candidate in the clinical management of colorectal tumors. Uses: Colorectal tumor. Synonyms: GYKI-13324; GYKI 13324; GYKI13324. N- (2-Chloroethyl) -N'- (4- ( ( ( (2-chloroethyl) amino) carbonyl) nitrosamino) -2, 3-dihydroxybutyl) -N-nitrosourea. Grades: 98%. CAS No. 76123-41-6. Molecular formula: C10H18Cl2N6O6. Mole weight: 389.19. | |
| GYKI-13380 | GYKI-13380is a bio-active compound. But no detailed information has been published ye. Synonyms: GYKI-13380; GYKI 13380; GYKI13380; LS-79445; LS 79445; LS79445. 4-((3-(Cyclopentyloxy)-4-methoxyphenyl)methyl)-2-imidazolidinone. Grades: 98%. CAS No. 75614-09-4. Molecular formula: C16H22N2O3. Mole weight: 290.36. | |
| GYKI 14166 | Efegatran is a thrombin inhibitor under the development of Eli Lilly. It can be used for the treatment of thromboembolic disorders. No development reported was reported for the treatment of Thrombosis. Uses: Thrombosis. Synonyms: Efegatran; RGH 2958; LY 294468; GYKI 14166; RGH2958; LY294468; GYKI14166; RGH-2958; LY-294468; GYKI-14166; (S)-1-(D-phenylalanyl)-N-((S)-5-guanidino-1-oxopentan-2-yl)pyrrolidine-2-carboxamide sulfate. Grades: 98%. CAS No. 83997-16-4. Molecular formula: C20H30N6O3.H2O4S. Mole weight: 500.57. | |
| GYKI14451 | GYKI14451 is a synthetic tripeptide inhibitor of thrombin. It has anti-atherosclerotic activity. Uses: Gyki14451 has anti-atherosclerotic activity. Synonyms: GYKI-14451; GYKI14451; LY-178207; GYKI 14451;LY 178207; LY178207;Boc-D-Phe-Pro-Arg-H;Tert-butyl ((R)-1-((S)-2-(((S)-5-guanidino-1-oxopentan-2-yl)carbamoyl)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)carbamate. Grades: 98%. CAS No. 69201-89-4. Molecular formula: C25H38N6O5. Mole weight: 502.61. | |
| GYKI-14451 sulfate | GYKI-14451 is a synthetic tripeptide inhibitor of thrombin.It has anti-atherosclerotic activity. Uses: Thrombosis. Synonyms: GYKI-14451 sulfate; GYKI 14451 sulfate; GYKI14451 sulfate; tert-butyl ((R)-1-((S)-2-(((S)-5-guanidino-1-oxopentan-2-yl)carbamoyl)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)carbamate hemisulfate; LY 178207; LY178207; LY-178207; Boc-D-Phe-Pro-Arg-H;69201-89-4 (free base). Grades: 98%. CAS No. 83861-29-4. Molecular formula: C50H76N12O10.H2O4S. Mole weight: 1103.30. | |
| GYKI-16638 HCl | GYKI-16638 is a novel antiarrhythmic agent, shows combined Class IB and Class III antiarrhythmic properties, resembling the electrophysiological manifestation seen after chronic amiodarone treatment. Uses: A novel antiarrhythmic agent. Synonyms: GYKI-16638 HCl; GYKI 16638 HCl; GYKI16638 HCl; N- [4- [2- [1- (2, 6-dimethoxyphenoxy) propan-2-yl-methylamino] ethyl] phenyl] methanesulfonamide; hydrochloride. Grades: ≥98%. CAS No. 307556-59-8. Molecular formula: C21H31ClN2O5S. Mole weight: 458.998. | |
| GYKI-20238 | GYKI-20238 is a thiazolidine compound with anti-amnesic activity. Uses: Anti-amnesic. Synonyms: GYKI-20238; GYKI20238; GYKI 20238; GYKI-20,238; GYKI20,238; GYKI 20,238. 2-Methylimino-3-(2,6-dichlorophenyl)-4-methylthiazolidine. Grades: ≥96%. CAS No. 30725-74-7. Molecular formula: C11H12Cl2N2S. Mole weight: 274.01. | |
| GYKI-23107 | GYKI-23107 is an antiarrhythmic agent with local anaesthetic activity. Uses: Antiarrhythmic agent. Synonyms: N1-(2,6-dimethylphenyl)-N2,N2-dimethylpropane-1,2-diamine; GYKI-23107; GYKI 23107; GYKI23107. Grades: 98%. CAS No. 83843-49-6. Molecular formula: C13H22N2. Mole weight: 206.33. | |
| GYKI-23107 dihydrochloride | GYKI-23107 is an antiarrhythmic agent with local anaesthetic activity. Uses: Antiarrhythmic agent. Synonyms: GYKI-23107 dihydrochloride; GYKI 23107 dihydrochloride; GYKI23107 dihydrochloride; 83843-49-6 (free base);N1-(2,6-dimethylphenyl)-N2,N2-dimethylpropane-1,2-diamine dihydrochloride. Grades: 98%. CAS No. 83843-39-4. Molecular formula: C13H24Cl2N2. Mole weight: 279.25. | |
| Gymnestrogenin | Gymnestrogenin is a triterpenoid compound found in the Gymnema sylvestre. with dual LXRα/β antagonistic property. Synonyms: (3S, 4aS, 5S, 6aR, 6aS, 6bR, 8aR, 9R, 10S, 12aR, 14bS)-4a, 9-bis(hydroxymethyl)-2, 2, 6a, 6b, 9, 12a-hexamethyl-1, 3, 4, 5, 6, 6a, 7, 8, 8a, 10, 11, 12, 13, 14b-tetradecahydropicene-3, 5, 10-triol. Grades: >98%. CAS No. 19942-02-0. Molecular formula: C30H50O5. Mole weight: 490.725. | |
| Gypenoside XLVI | Gypenosides are triterpenoid saponins isolated from Gynostemma pentaphyllum. Synonyms: Gypenoside XLVI; 94705-70-1; GypenosideXLVI; 2-[2-[[2,12-Dihydroxy-4,4,8,10,14-pentamethyl-17-[6-methyl-2-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol; HY-N6252. Grades: >98%. CAS No. 94705-70-1. Molecular formula: C48H82O19. Mole weight: 963.15. | |
| H2L5186303 | H2L5186303 is a potent and selective lysophosphatidic acid 2 (LPA2) receptor antagonist (IC50 = 8.9, 1230 and 27354 nM for LPA2, LPA3 and LPA1 receptors respectively, in a LPA-elicited calcium mobilization assay). Synonyms: H2L5186303; H2L 5186303; H2L-5186303; (Z,Z)-4,4'-[1,3-Phenylenebis(oxy-4,1-phenyleneimino)]bis[4-oxo-2-butenoic acid. Grades: ≥98% by HPLC. CAS No. 139262-76-3. Molecular formula: C26H20N2O8. Mole weight: 488.45. | |
| H2L 5765834 | H2L 5765834 is an antagonist of the lysophosphatidic acid receptors LPA1, LPA5 and LPA3 (IC50 = 94, 463 and 752 nM, respectively). H2L 5765834 may be used for the treatment of systemic sclerosis. Uses: Potential treatment of systemic sclerosis. Synonyms: H2L 5765834; H2L5765834; H2L-5765834; 2,3-Dihydro-2-[3-(4-nitrophenoxy)phenyl]-1,3-dioxo-1H-isoindole-5-carboxylic acid; 2-[3-(4-nitrophenoxy)phenyl]-1,3-dioxoisoindole-5-carboxylic acid. Grades: ≥99% by HPLC. CAS No. 420841-84-5. Molecular formula: C21H12N2O7. Mole weight: 404.33. | |
| H3B-6527 | H3B-6527 is a potent, highly selective and orally active FGFR4 inhibitor with potential antineoplastic activity. Synonyms: N-{2-[ (6-{[ (2, 6-Dichloro-3, 5-dimethoxyphenyl)carbamoyl] (methyl)amino}-4-pyrimidinyl)amino]-5- (4-ethyl-1-piperazinyl)phenyl}acrylamide; H3B-6527; H3B 6527; H3B6527. CAS No. 1702259-66-2. Molecular formula: C29H34Cl2N8O4. Mole weight: 629.543. | |
| H 89 2HCl | H 89 2HCl is a cell permeable and potent PKA inhibitor with Ki of 48 nM in a cell-free assay, wihich is 10-fold selective for PKA than PKG, 500-fold greater selectivity than PKC, MLCK, calmodulin kinase II and casein kinase I/II. Synonyms: N-[2-[[3-(4-Bromophenyl)-2-propenyl]amino]ethyl]-5-isoquinolinesulfonamide dihydrochloride. Grades: ≥98%. CAS No. 130964-39-5. Molecular formula: C20H20BrN3O2S·2HCl. Mole weight: 519.28. | |
| H-8 dihydrochloride | H-8 is a cell-permeable and potent inhibitor of PKA and PKG with Ki values of 1.2 and 0.48 μM, respectively. It also slightly inhibits PKC and MLCK with Ki values of 15 and 68 μM. Synonyms: N-[2-(Methylamino)ethyl]-5-isoquinolinesulfonamide dihydrochloride. Grades: ≥98%. CAS No. 113276-94-1. Molecular formula: C12H15N3O2S·2HCl. Mole weight: 338.3. | |
| HA-1004 dihydrochloride | HA-1004 dihydrochloride is an inhibitor of PKA, PKC, cGKI, MYLK, and calcium channel protein. Synonyms: 5-Isoquinolinesulfonamide, N-[2-[(aminoiminomethyl)amino]ethyl]-, hydrochloride (1:2); 5-Isoquinolinesulfonamide, N-[2-[(aminoiminomethyl)amino]ethyl]-, dihydrochloride; HA 1004 dihydrochloride; HA1004 dihydrochloride; N-(2-guanidinoethyl)-5-isoquinolinesulfonamide dihydrochloride. Grades: ≥98%. CAS No. 92564-08-4. Molecular formula: C12H15N5O2S.2HCl. Mole weight: 366.27. | |
| HA-155 | HA-155 is an autotaxin inhibitor. Autotaxin, also known as ectonucleotide pyrophosphatase/phosphodiesterase 2 (NPP2 or ENPP2), is a secreted enzyme converting lysophosphatidylcholine (LPC) into lysophosphatidic acid (LPA), which is responsible for tumor cell motility stimulation. Synonyms: HA 155; HA155; Autotaxin Inhibitor IV; Boronic acid, B- [4- [ [4- [ [3- [ (4-fluorophenyl) methyl] -2, 4-dioxo-5-thiazolidinylidene] methyl] phenoxy] methyl] phenyl] -. Grades: ≥95%. CAS No. 1229652-22-5. Molecular formula: C24H19BFNO5S. Mole weight: 463.3. | |
| Halcinonide | Halcinonide is a high potency corticosteroid used in topical preparations as an anti-inflammatory agent. Synonyms: Pregn-4-ene-3,20-dione, 21-chloro-9-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (11β,16α)-; (11β,16α)-21-Chloro-9-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregn-4-ene-3,20-dione; Pregn-4-ene-3,20-dione, 21-chloro-9-fluoro-11β,16α,17-trihydroxy-, cyclic 16,17-acetal with acetone; Adcortin; Alcinonide; Halciderm; Halcimat; Halog; SQ 18566. Grades: >98%. CAS No. 3093-35-4. Molecular formula: C24H32ClFO5. Mole weight: 454.96. | |
| Halicloic acid A | Halicloic acid A is a potent IDO inhibitor. Synonyms: Halicloic Acid A; CHEMBL2087614; BDBM50421038; 4-(4'-(2''-methoxy-4''-hydroxy-3'',6''-dimethylbenzoyloxy)-3',5',6'-trimethyl-2'-methoxybenzoyloxy)-2-methoxy-3,6-dimethylbenzoic acid. Grades: > 98%. CAS No. 1393581-27-5. Molecular formula: C38H56O5. Mole weight: 592.85. | |
| Halofuginone hydrobromide | Halofuginone hydrobromide is a salt form of Halofuginone, which is a coccidiostat used in veterinary medicine. Synonyms: DL-trans-7-Bromo-6-chloro-3-[3-(3-hydroxypiperidin-2-yl)-2-oxopropyl]-3H-quinazolin-4-one hydrobromide. CAS No. 64924-67-0. Molecular formula: C16H18Br2ClN3O3. Mole weight: 495.596. | |
| Halofuginone lactate | Halofuginone lactate is a halogenated derivative of febrifugine. Halofuginone inhibits prolyl-tRNA synthetase in an ATP-dependent manner with a Ki of 18.3 nM. Grades: >95%. CAS No. 82186-71-8. Molecular formula: C19H23BrClN3O6. Mole weight: 504.76. | |
| HAMNO | HAMNO is a novel protein interaction inhibitor of replication protein A (RPA), which is involved in the ATR/Chk1 pathway. HAMNO acts by binding to the N-terminal DBD-F domain of RPA70. HAMNO inhibits both ATR autophosphorylation and phosphorylation of RPA32 Ser33 by ATR. It is a potential treatment of cancer. Uses: Potential antitumor drug. Synonyms: HAMNO; CID 6335338, MLS000737724, NSC111847, NSC-111847; NSC111847. 1-(2-Hydroxyphenyliminomethyl)-2-naphthol; 2(1H)-Naphthalenone, 1-[[(2-hydroxyphenyl)amino]methylene]-. Grades: 99%. CAS No. 138736-73-9. Molecular formula: C17H13NO2. Mole weight: 263.29. | |
| HBX 41108 | HBX 41108 is an inhibitor of ubiquitin-specific protease (USP) 7 (IC50 = 424 nM). HBX 41108 inhibits USP7-mediated p53 deubiquitination (IC50 = 0.8 μM). HBX 41108 stabilizes p53, activates transcription of a p53 target gene without inducing genotoxic stress, and inhibits cancer cell growth. HBX 41108 induces p53-dependent apoptosis in p53 wild type and null isogenic cancer cell lines. Synonyms: HBX 41108; HBX-41108; HBX41108; HBX 41,108; HBX-41,108; HBX41,108. 7-Chloro-9-oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile. Grades: ≥98% by HPLC. CAS No. 924296-39-9. Molecular formula: C13H3ClN4O. Mole weight: 266.64. | |
| HCV371 | HCV371 is a potent and selective HCV NS5B polymerase inhibitor. It binds the NS5B with an apparent dissociation constant of 150 nM, which leads to high selectivity and lack of cytotoxicity in the antiviral assays. It displayed broad inhibitory activities against the NS5B RdRp enzyme. It showed no inhibitory activity against a panel of human polymerases, including mitochondrial DNA polymerase gamma and other unrelated viral polymerases. Synonyms: HCV-371; HCV 371; HCV371. (R)-2-(5-cyano-8-methyl-1-propyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic acid. Grades: 98%. CAS No. 675184-27-7. Molecular formula: C18H20N2O3. Mole weight: 312.37. | |
| H-D-3-Pal-OH 2HCl | H-D-3-Pal-OH 2HCl, a synthetic peptide of scientific interest, has the potential to be a promising avenue in the pursuit of new treatments for diseases of varying kinds. Research into the properties of this compound suggests its ability to inhibit cell proliferation and promote apoptosis in oncogenic cells. Interestingly, it may also function as an immunomodulator and possess therapeutic applications towards autoimmune disorders. These findings speak to the complex and multifaceted nature of H-D-3-Pal-OH 2HCl and the implications it could have in furthering scientific understanding of these conditions. Synonyms: (R)-2-Amino-3-(pyridin-3-yl)propanoic acid dihydrochloride; H-D-3-Pal-OH.2HCl; 3-(3-Pyridyl)-D-alanine dihydrochloride. Grades: 95%. CAS No. 93960-21-5. Molecular formula: C8H12Cl2N2O2. Mole weight: 239.10. | |
| H-D-allo-Threonine Methyl Ester Hydrochloride | H-D-allo-Threonine Methyl Ester Hydrochloride is used to prepare hepatitis A virus 3C cysteine protease inhibitors. Synonyms: H-D-allo-Thr-OMe HCl; (2R,3R)-Methyl 2-Amino-3-hydroxybutanoate Hydrochloride; Methyl D-allo-Threoninate Hydrochloride. Grades: ≥95%. CAS No. 60538-18-3. Molecular formula: C5H12ClNO3. Mole weight: 169.61. | |
| H-D-Leu-Thr-Arg-PNA | Synonyms: ACMC-20mq5f. Grades: 95%. CAS No. 122630-72-2. Molecular formula: C22H36N8O6. Mole weight: 508.6. | |
| HDMAPP triammonium salt | HDMAPP is a photo-crosslinkable biotin derivative that targets the HMBPP Site of BTN3A1, and activates Vγ9Vδ2 T cells, which plays a key role in the cross talk of the innate and adaptive immune system. Synonyms: HMBPP triammonium; [[(E)-4-hydroxy-3-methylbut-2-enoxy]-oxidophosphoryl] phosphate triammonium salt. Grades: ≥90%. CAS No. 443892-56-6. Molecular formula: C5H9O8P2·3NH4. Mole weight: 313.2. | |
| H-D-Phe-Pro-arginal | H-D-Phe-Pro-arginal is a thrombin inhibitor which is being developed by IVAX for the potential treatment of thromboembolic disorders. It has a similar efficacy to heparin at the highest dose studied. Uses: H-d-phe-pro-arginal is developed for the potential treatment of thromboembolic disorders. Synonyms: GYKI-14166;GYKI14166;RGH-2958;GYKI 14166;RGH 2958;RGH2958;LY-294468;LY294468;Efegatran;(S)-1-(D-phenylalanyl)-N-((S)-5-guanidino-1-oxopentan-2-yl)pyrrolidine-2-carboxamide. Grades: 98%. CAS No. 60503-05-1. Molecular formula: C20H30N6O3. Mole weight: 402.57. | |
| Hederacolchiside E | Hederacolchiside E is extracted from Pulsatilla chinensis (Bunge) Regel. Synonyms: Hederacolchiside E; 33783-82-3; Hederacholchiside E; CHEMBL4165893; DTXSID201316054; AKOS040760443; HY-107311; CS-0027959; D84974. Grades: >98%. CAS No. 33783-82-3. Molecular formula: C65H106O30. Mole weight: 1367.5. | |
| Hederagenin 3-O-α-L-rhamnopyranosyl(1?2)-(β-D-glucopyranosyl(1?4))-α-L-arabinopyranoside | Cas No. 68027-15-6. | |
| Hederagenin - 3-O-β-D- Galactosyl( 1?3)-β-D-glucosyl( 1?3)-α-L-rhamnosyl(1?2)-α-L-arabinoside | Hederagenin - 3-O-β-D- Galactosyl( 1?3)-β-D-glucosyl( 1?3)-α-L-rhamnosyl(1?2)-α-L-arabinoside is a triterpenoids isolated from pulsatilla chinensis BungeRegel. Pulsatilla chinensis (Bunge) Regel is a botanical with a long history of medical use in China, which exhibits "blood-cooling" and detoxification activities. The roots of P. chinensis have been widely used in the traditional Chinese medicine for adjunctive treatment of intestinal amebiasis, malaria, vaginal trichomoniasis, bacterial infections and malignant tumor. Grades: > 98%. Molecular formula: C53H86O22. Mole weight: 1075.24. | |
| Hematoporphyrin | Hematoporphyrin is a substrate for affinity chromatography of heme-binding proteins. Synonyms: Photodyn; Sensibion. Grades: >98%. CAS No. 14459-29-1. Molecular formula: C34H38N4O6. Mole weight: 598.69. | |
| Hemokinin 1 (human) | Hemokinin 1 (human) is an endogenous substance P homolog and acts as a selective agonist at the tachykinin NK1 receptor (IC50 = 1.8, 370 and 480 nM for NK1, NK3 and NK2 receptors, respectively). It induces proliferation of B-cells in vitro and exhibits antihypertensive activity in vivo. Synonyms: Hemokinin 1 (human); 491851-53-7; HemokininHK-1 (human); DTXSID60746659. CAS No. 491851-53-7. Molecular formula: C54H84N14O14S. Mole weight: 1185.4. | |
| Henagliflozin | Henagliflozin, a glucoside compound, has been found to be a sodium-glucose transporter 2 inhibitor that could probably be effective in hyperglycaemic. It is under Phase I trial against Type-2 diabetes mellitus. Synonyms: UNII-21P2M98388; 21P2M98388; Henagliflozin; SHR3824; SHR-3824; SHR 3824; (1R,2S,3S,4R,5R)-5-[4-chloro-3-[(4-ethoxy-3-fluorophenyl)methyl]phenyl]-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol. Grades: 98%. CAS No. 1623804-44-3. Molecular formula: C22H24ClFO7. Mole weight: 454.88. | |
| Heparan Sulfate | Heparan sulfate, a complex and linear polysaccharide in which the backbone is composed of repeating sulfated disaccharide units, exists as part of glycoproteins named heparan sulfate proteoglycans, which are expressed abundantly on the cell surface and in the extracellular matrix. Synonyms: Alpha-idosane; HHS 5; Heparan N-Sulfate; Heparan Sulfate; Heparan Sulphate; Heparitin; Heparitin Monosulfate; N-Acetylheparan Sulfate; Suleparoid; Tavidan. CAS No. 9050-30-0. Molecular formula: (C24H30N2O39S6)n. | |
| Heparin Binding Peptide | Heparin Binding Peptide, a heparin-binding peptide isolated from a proteolytic hydrolysate of bovine lactoferrin, increase the endothelialisation of prosthetic materials in vitro. Synonyms: Trp-Gln-Pro-Pro-Arg-Ala-Arg-Ile; WQPPRARI. Molecular formula: C47H74N16O10. Mole weight: 372.69. | |
| Heparin disaccharide I-S, tetrasodium salt | It is a predominant disaccharide produced from heparin by heparinase I and II. Synonyms: 2-Deoxy-4-O-(4-deoxy-2-O-sulfo-α-L-threo-hex-4-enopyranuronosyl)-2-(sulfoamino)-D-glucose 6-(hydrogen sulfate) Sodium Salt; sodium (2R,3R,4S)-2-((2R,3S,4R,5R)-4,6-dihydroxy-5-(sulfonatoamino)-2-(sulfonatooxymethyl)tetrahydro-2H-pyran-3-yloxy)-4-hydroxy-3-(sulfonatooxy)-3,4-dihydro-2H-pyran-6-carboxylate; alpha-DeltaUA-2S-[1->4]-GlcNS-6S; Tetrasodium 2-deoxy-4-O-(4-deoxy-2-O-sulfonato-α-L-threo-hex-4-enopyranuronosyl)-6-O-sulfonato-2-(sulfonatoamino)-D-glucopyranose. Grades: ≥98%. CAS No. 136098-10-7. Molecular formula: C12H15NNa4O19S3. Mole weight: 665.40. | |
| Heparin Sodium | Heparin sodium is a sodium salt of heparin which is a naturally-occurring anticoagulant used for anticoagulation for cardiovascular disease. It is an inhibitor of activated coagulation factors such as Factors Xa and IIa (thrombin). Uses: Anticoagulation for cardiovascular disease. Synonyms: Adomiparin Sodium; Alfa 87-120; Ardeparin Sodium; Badyket; Bemiparin Sodium; Dalteparin Sodium; Deligoparin Sodium; Depo-Heparin; Fragmin; Hepaflush; Hepagumin; Hepalean; Heprinar; Hepsal; Lipo-Hepin; Liquaemin Sodium; Logiparin; Longheparin; Minolteparin Sodium; Monoparin; Nadroparine Sodium; Normiflo; Panheprin; Parnaparin Sodium; Pularin; Reviparin Sodium; Semuloparin Sodium; Sevuparin Sodium; Sodium Acid Heparin; Sodium Heparin; Sodium Heparinate; Thrombo-Hepin. CAS No. 9041-8-1. Molecular formula: (C12H16NS2Na3)20. Mole weight: 6000-20000. | |
| Heparosan from E. coli K5 | Heparosan is an endogenous Glycosaminoglycan biosynthesized and secreted by E. coli K5. Heparosan serves as the starting carbon backbone for the chemoenzymatic synthesis of heparin, a widely used clinical anticoagulant drug. Synonyms: Heparosan; Heparosan (E. coli K5). | |
| Heptadecanedioic acid | Heptadecanedioic acid (CAS# 2424-90-0 ) is a useful research chemical. Synonyms: 1,15-PENTADECANEDICARBOXYLIC ACID; HEPTADECANEDIOIC ACID; heptadecandionic acid; 1,17-Heptadecanedioic acid. Grades: 95 %. CAS No. 2424-90-0. Molecular formula: C17H32O4. Mole weight: 300.43. | |
| Heptakis(6-deoxy-6-thio)-beta-cyclodextrin | Heptakis(6-deoxy-6-thio)-beta-cyclodextrin is a vital compound extensively used in the biomedical industry. With its exceptional binding capabilities, it is commonly employed in drug formulation and delivery systems. This product plays a significant role in enhancing the solubility and stability of various drugs, allowing for improved therapeutic outcomes. Synonyms: 6-Deoxy-6-thio-b-cyclodextrin; 160661-60-9; Heptakis-(6-Mercapto-6-deoxy)-beta-Cyclodextrin; SCHEMBL23014690; AS-84178; A906604. CAS No. 160661-60-9. Molecular formula: C42H70O28S7. Mole weight: 1247.4. | |
| Heptaminol Hydrochloride | Heptaminol Hydrochloride is an amino alcohol which is classified as a vasoconstrictor used in the treatment of low blood pressure, particularly orthostatic hypotension. Uses: A vasoconstrictor. Synonyms: 6-Amino-2-methyl-2-heptanol hydrochloride; Cardiosintol. Grades: ≥95%. CAS No. 543-15-7. Molecular formula: C8H19NO. Mole weight: 181.7. | |
| Heptanoicacid, 5-methyl- | 5-Methylheptanoic acid is a versatile fatty acid renowned for its potent biocidal properties, making it a popular choice in the biomedical industry. This multifaceted compound has exhibited remarkable efficacy in treating several pathogenic infections caused by gram-positive bacteria, viz. Staphylococcus aureus and Streptococcus pneumoniae. Notably, this chemical marvel holds tremendous promise in combatting acne outbreaks by impeding bacterial proliferation on the skin. Its effectiveness and versatility make it a pivotal fatty acid in the field of biomedicine. Synonyms: 5-METHYLHEPTANOIC ACID. CAS No. 1070-68-4. Molecular formula: C8H16O2. Mole weight: 144.21. | |
| Hernandulcin | hernandulcin is a sesquiterpene found in Phyla dulcis. Synonyms: Hernandulcin; 95602-94-1; UNII-7V22TJL7NX; (6S)-6-[(2S)-2-hydroxy-6-methylhept-5-en-2-yl]-3-methylcyclohex-2-en-1-one; 7V22TJL7NX. Grades: 95%. CAS No. 95602-94-1. Molecular formula: C15H24O2. Mole weight: 236.35. | |
| Herzuma | Herzuma is a biosimilar of trastuzumab approved by EU for the treatment of patients with early breast cancer, metastatic breast cancer or metastatic gastric cancer whose tumors have either receptor tyrosine-protein kinase erbB-2 (HER2) overexpression or HER2 gene amplification. Uses: Cancer therapy. | |
| Hexadecyl b-D-maltopyranoside | Hexadecyl b-D-maltopyranoside is used as a detergent for the purification, extraction and solubilization of membrane-bound proteins. Synonyms: n-Hexadecyl b-D-maltoside. CAS No. 98064-96-1. Molecular formula: C28H54O11. Mole weight: 566.729. | |
| Hexadecyl propionate | Hexadecyl propionate, a synthetic compound with broad applicability, is extensively utilized in cosmetic products for its emollient effects. This molecular agent functions to both soften and soothe the skin while simultaneously shielding it from environmental threats, a remarkable feat. Furthermore, this versatile compound has found applications within various pharmaceutical formulations, particularly those designed for treating a myriad of dermatological disorders, such as eczema and psoriasis. Synonyms: 1-Hexadecanol, propanoate; Propionic acid hexadecyl ester; NSC 53827; NSC 67972; 1-Hexadecanol, 1-propanoate. Grades: ≥95%. CAS No. 6221-96-1. Molecular formula: C19H38O2. Mole weight: 298.50. | |
| Hexafluorenium bromide | Hexafluronium bromide is.a cholinesterase inhibitor used in anesthesiology to prolong and potentiate the skeletal muscle relaxing action of suxamethonium during surgery. Uses: Acetylcholine receptor. Synonyms: Mylaxen; 9H-fluoren-9-yl-[6-[9H-fluoren-9-yl(dimethyl)azaniumyl]hexyl]-dimethylazanium;dibromide. Grades: ≥98%. CAS No. 317-52-2. Molecular formula: C36H42N2.2Br. Mole weight: 662.54008. | |
| Hexakis(6-mercapto-6-deoxy)-alpha-cyclodextrin | Hexakis(6-mercapto-6-deoxy)-alpha-cyclodextrin is a compound of utmost importance in the biomedical sector, showcasing an exclusive configuration that renders it exemplary for drug conveyance. It assumes a pivotal function in aiming drug delivery systems, thereby facilitating efficacious research of an array of ailments such as cancer, inflammation and infections. Synonyms: Hexakis(6-mercapto-6-deoxy)-a-cyclodextrin; Hexakis(6-mercapto-6-deoxy)-α-cyclodextrin. CAS No. 180839-60-5. Molecular formula: C36H60O24S6. Mole weight: 1069.24. | |
| Hexa-L-Tyrosine | Hexa-L-Tyrosine, a molecule frequently employed in the creation of peptide-based therapeutic treatments for afflictions such as cancer and neurodegenerative conditions, possesses potent antioxidant capabilities. It may also serve as a fundamental unit in the assembly of peptides displaying enhanced pharmacologically relevant traits. Synonyms: H-Tyr-Tyr-Tyr-Tyr-Tyr-Tyr-OH; H-YYYYYY-OH; L-tyrosyl-L-tyrosyl-L-tyrosyl-L-tyrosyl-L-tyrosyl-L-tyrosine; Hexatyrosine. Grades: 95%. CAS No. 6934-38-9. Molecular formula: C54H56N6O13. Mole weight: 997.05. | |
| Hexamidine diisethionate | Synonyms: Desomedine; Hexomedine; Ophtamedine; 2-Hydroxyethanesulfonic acid, compound with 4, 4'-[hexane-1, 6-diylbis (oxy)]bis[benzenecarboxamidine] (2:1). Grades: 98%. CAS No. 659-40-5. Molecular formula: C24H38N4O10S2. Mole weight: 606.71. | |
| Hexapeptide-2 | Hexapeptide-2 is a synthetic peptide used as a skin conditionor. | |
| Hexapeptide-3 | Synonyms: H-Glu-Glu-Met-Gln-Arg-Arg-NH2. Grades: 98%. CAS No. 1205679-02-2. Molecular formula: C32H58N14O11S. Mole weight: 847. | |
| Hexapeptide-9 | Hexapeptide-9 is an anti-aging hexapeptide that triggers the skin into regeneration of its damaged cells. Synonyms: Glycyl-L-prolyl-L-glutaminylglycyl-L-prolyl-L-glutamine; Collaxyl; Hexapeptide 9; L-Glutamine, glycyl-L-prolyl-L-glutaminylglycyl-L-prolyl-. Grades: 98%. CAS No. 885024-94-2. Molecular formula: C24H38N8O9. Mole weight: 582.61. | |
| HFI 142 | HFI 142 is an insulin-regulated aminopeptidase (IRAP) inhibitor (Ki = 2.01 μM). HFI 142 improves memory in control and memory-deficient mice models. Synonyms: HFI-142; HFI 142; HFI142; Ethyl 2-amino-7-hydroxy-4-(3-pyridinyl)-4H-1-benzopyran-3-carboxylate; 2-Amino-7-hydroxy-4-pyridin-3-yl-4H-chromene-3-carboxylic acid ethyl ester. Grades: ≥98% by HPLC. CAS No. 332164-34-8. Molecular formula: C17H16N2O4. Mole weight: 312.32. | |
| HIDC iodide | HIDC iodide is a carbocyanine dye that stains mitochondria of live cells. Synonyms: DiIC1(5); 2-[5-(1,3-dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)-1,3-pentadienyl]-1,3,3-trimethyl-3H-indolium iodide; Hexacyanin 2; HIDCI. CAS No. 36536-22-8. Molecular formula: C27H31IN2. Mole weight: 510.45. | |
| Hidrosmin | Hidrosmin is a biomedical product used in the research of chronic venous insufficiency. Synonyms: 4H-1-Benzopyran-4-one, 7-[[6-O-(6-deoxy-α-L-mannopyranosyl)?-β-D-glucopyranosyl]?oxy]?-5-(2-hydroxyethoxy)?-2-[3-(2-hydroxyethoxy)?-4-methoxyphenyl]?-, mixt. with 7-[[6-O-(6-deoxy-α-L-mannopyranosyl)?-β-D-glucopyranosyl]?oxy]?-5-(2-hydroxyethoxy)?-2-(3-hydroxy-4-methoxyphenyl)?-4H-1-benzopyran-4-one and 7-[[6-O-(6-deoxy-α-L-mannopyranosyl)?-β-D-glucopyranosyl]?oxy]?-5-hydroxy-2-[3-(2-hydroxyethoxy)?-4-methoxyphenyl]?-4H-1-benzopyran-4-one Mixture. CAS No. 218433-35-3. Molecular formula: C32H40O17.C30H36O16.C30H36O16. | |
| HIF-2a Translation Inhibitor 76 | A cell-permeable HIF-2a translation inhibitor (IC50 value 5 μM). It inhibits HIF-2a translation via enhancing the binding of IRP1 (Iron-Regulatory Protein 1) to the IRE (Iron-Responsive Element) region at the 5' UTR of the HIF-2α mRNA. Synonyms: HIF-2a translation inhibitor; HIF-2|A-IN-4; 882268-69-1; methyl 3-[ (2E) -2-[cyano (methylsulfonyl) methylidene]hydrazinyl]thiophene-2-carboxylate; HIF-2alpha-IN-4; SCHEMBL781448; HMS554D20; Methyl 3- ( ([cyano (methanesulfonyl) methylidene]amino) amino) thiophene-2-carboxylate; CCG-45847; MS-24103; HY-136748; CS-0133535; SR-01000635592-1; methyl 3- (2- (cyano (methylsulfonyl) methylene) hydrazineyl) thiophene-2-carboxylate. Grades: 99%. CAS No. 882268-69-1. Molecular formula: C9H9N3O4S2. Mole weight: 287.32. | |
| HIOC | HIOC is a selective tropomyosin-related kinase receptor B (TrkB) receptor agonist with neuroprotective property. HIOC was shown to prevent retinas from light-induced retinal degeneration (LIRD) in vivo. HIOC is used in the treatment of early brain injury following subarachnoid hemorrhage (SAH). Synonyms: N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]-2-oxo-3-piperidinecarboxamide. Grades: ≥98% by HPLC. CAS No. 314054-36-9. Molecular formula: C16H19N3O3. Mole weight: 301.34. | |
| Hippeastrine | Hippeastrine is an indole alkaloid isolated from the Amaryllidaceae, which exhibits cytotoxic activity. Synonyms: (+)-Hippeastrine; 1-Methyl-5α-hydroxy-9,10-methylenedioxy-1,2,3,5aα,11bα,11cβ-hexahydro[2]benzopyrano[3,4-g]indole-7(5H)-one; 5α-Hydroxy-1-methyl-9,10-[methylenebis(oxy)]lycorenan-7-one. Grades: > 95%. CAS No. 477-17-8. Molecular formula: C17H17NO5. Mole weight: 315.32. | |
| Hirsutine | Hirsutine is an alkaloid isolated from Uncaria rhynchophylla, showing anti-cancer activity. Synonyms: Hirsutine; 7729-23-9; UNII-W596OF93C7; W596OF93C7; methyl (E)-2-[(2S,3R,12bR)-3-ethyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate; CHEMBL327134; (E)-16,17-Didehydro-17-methoxy-17,18-seco-3-beta-yohimban-16-carboxylic acid methyl ester; Corynan-16-carboxylic acid, 16,17-didehydro-17-methoxy-, methyl ester, (3-beta,16E)-; 17,18-Seco-3-beta-yohimban-16-carboxylic acid, 16,17-didehydro-17-methoxy-, methyl ester, (E)-; 76376-57-3; DIHYDROTESTOSTERONEBENZOATE; hirsutine, (3beta,16E)-isomer; DTXSID801045724; HY-N2193; BDBM50396011; AKOS040760133; Corynan-16-carboxylic acid, 16,17-didehydro-17-methoxy-, methyl ester, (3.beta.,16E)-; 17,18-Seco-3.beta.-yohimban-16-carboxylic acid, 16,17-didehydro-17-methoxy-, methyl ester, (E)-. Grades: 98%. CAS No. 7729-23-9. Molecular formula: C22H28N2O3. Mole weight: 368.47. | |
| Hispidin | Hispidin is a polyphenol isolated from Pteris ensiformis. It exhibits antioxidant, anti-inflammatory, and cytoprotective properties. Hispidin is also a precursor of fungal luciferin, emits bioluminenscence in the luminous fungal fruiting body. Synonyms: 6-(3,4-dihydroxystyrl)-4-hydroxy-2-pyrone; 6-[(E)-2-(3,4-dihydroxyphenyl)vinyl]-4-hydroxy-2H-pyran-2-one. Grades: ≥95%. CAS No. 555-55-5. Molecular formula: C13H10O5. Mole weight: 246.2. | |
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