BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Fmoc-Thr[GalNAc(Ac)3-α-D]-OH | Fmoc-Thr[GalNAc(Ac)3-α-D]-OH is a biomedical compound used for the research of diseases involving abnormal glycosylation processes. It functions as a glycosylation inhibitor, targeting enzymes responsible for glycan modification. This product aids in the study and understanding of glycosylation-related disorders. Synonyms: Fmoc-Thr(Ac3AcNH-α-Gal)-OH; Fmoc-L-Thr(TnAc4)-OH; N-alpha-(9-Fluorenylmethyloxycarbonyl)-O-(2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-alpha-D-galactopyranosyl)-L-threonine; Fmoc-Thr[GalNAc(Ac)3-alpha-D]-OH. Grades: ≥97% by HPLC. CAS No. 116783-35-8. Molecular formula: C33H38N2O13. Mole weight: 670.66. |  |
| Fmoc-trans-4-methyl-L-Pro-OH | Synonyms: N-(9-Fluorenylmethoxycarbonyl)-(2S,4R)-4-methylproline; 1-(9H-Fluorene-9-ylmethoxycarbonyl)-4beta-methyl-L-proline; Fmoc-trans-4-Amc-OH; Fmoc-trans-4-methyl-L-proline; (2S,4R)-Fmoc-4-Methyl-L-Pro-OH; (4R)-1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-4-methyl-L-proline; 1,2-Pyrrolidinedicarboxylic acid, 4-methyl-, 1-(9H-fluoren-9-ylmethyl) ester, (2S,4R)-. Grades: 98% by HPLC. CAS No. 333777-34-7. Molecular formula: C21H21NO4. Mole weight: 351.39. | |
| Fmoc-Val-Cit-PAB | Fmoc-Val-Cit-PAB is a linked conjugate for ADC. Synonyms: Fmoc-Val-Cit-PAB-OH. CAS No. 159858-22-7. Molecular formula: C33H39N5O6. Mole weight: 601.704. | |
| Fmoc-Val-Cit-PAB-PNP | A useful protective group in antibody drug conjugates. Synonyms: N-[ (9H-Fluoren-9-ylmethoxy) carbonyl]-L-valyl-N5-carbamoyl-N-[4- ({[ (4-nitrophenoxy) carbonyl]oxy}methyl) phenyl]-L-ornithinamide. Grades: ≥98%. CAS No. 863971-53-3. Molecular formula: C40H42N6O10. Mole weight: 766.79. | |
| Fondaparinux Sodium | Fondaparinux sodium is a factor Xa inhibitor that mediates the interaction of herparin with antithrombins. It is used for the prevention of venous thromboembolism after surgery. Synonyms: Arixtra; Quixidar; Fondaparinux sodium; Fondaparinux sodium salt; PENTA; Arixtra; Xantidar; SR 90107A; IC-85158; SR-90107A; SR90107A; IC 85158; IC85158. Grades: > 95%. CAS No. 114870-03-0. Molecular formula: C31H43N3Na10O49S8. Mole weight: 1728.035. | |
| Foresaconitine | Foresaconitine is a norditerpenoid alkaloid isolated from the processed tubers of Aconitum carmichaeli. Synonyms: Vilmorrianine C. Grades: >98%. CAS No. 73870-35-6. Molecular formula: C35H49NO9. Mole weight: 627.76. | |
| Formyl Ciprofloxacin | An impurity of Ciprofloxacin, which is a broad-spectrum antimicrobial carboxyfluoroquinoline, an fluoroquinolone antibiotic that is widely used as an antimicrobial and immunomodulatory agent. Synonyms: Formylciprofloxacin (M4); Ciprofloxacin Formamide. Grades: > 95%. CAS No. 93594-39-9. Molecular formula: C18H18FN3O4. Mole weight: 359.36. | |
| Forsythoside I | Forsythoside I is a natural product isolated from forsythia suspense (thunb.) vahl, showing anti-inflammatory activities. Synonyms: Isoforsythoside A. Grades: 0.98. CAS No. 1177581-50-8. Molecular formula: C29H36O15. Mole weight: 624.59. | |
| Fosbretabulin | Fosbretabulin, also called as CA4P, has antitumor activity against anaplastic thyroid cancer (ATC) cell lines. Fosbretabulin, a novel water-soluble vascular-disrupting agent, is a phosphate derivative of a natural stilbenoid phenol derived from the African bush willow (Combretum caffrum). Synonyms: [2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl] dihydrogen phosphate; 3,4,5-trimethoxy-3'-hydroxy-4'-methoxystilbene; CA4DP; combretastatin A-4; 168555-66-6 (fosbretabulin disodium); 82855-09-2 (combretastatin); 117048 -59-6 (combretastatin A4). Grades: >98%. CAS No. 222030-63-9. Molecular formula: C18H21O8P. Mole weight: 396.33. | |
| Fosbretabulin disodium | Fosbretabulin disodium is the disodium salt of a water-soluble phosphate derivative of a natural stilbenoid phenol derived from the African bush willow (Combretum caffrum) with potential vascular disrupting and antineoplastic activities. Upon administration, the prodrug fosbretabulin is dephosphorylated to its active metabolite, the microtubule-depolymerizing agent combretastatin A4, which binds to tubulin dimers and prevents microtubule polymerization, resulting in mitotic arrest and apoptosis in endothelial cells. In addition, this agent disrupts the engagement of the endothelial cell-specific junctional molecule vascular endothelial-cadherin (VE-cadherin) and so the activity of the VE-cadherin/β-catenin/Akt signaling pathway, which may result in the inhibition of endothelial cell migration and capillary tube formation. As a result of fosbretabulin's dual mechanism of action, the tumor vasculature collapses, resulting in reduced tumor blood flow and ischemic necrosis of tumor tissue. Synonyms: Combretastatin A-4 phosphate disodium, CA4P; CA4DP; Combretastatin A-4 phosphate. CAS No. 168555-66-6. Molecular formula: C18H19Na2O8P. Mole weight: 440.295. | |
| Fosdevirine | Fosdevirine is a highly potent next-generation Anti-HIV nonnucleoside reverse transcriptase inhibitor (NNRTI) with an EC50 of 11 nM. It is a novel and once-daily (QD) inhibitor with activity against efavirenz-resistant strains. It demonstrated potent antiviral activity in treatment-naive HIV-infected subjects, and had favorable PK and resistance profiles. It was originally developed by idenix pharmaceuticals and was in clinical phase 2, but now it has been terminated. Uses: Fosdevirine has potent antiviral activity. Synonyms: GSK2248761; GSK-2248761; GSK 2248761; GSK2248761A; GSK-2248761A; GSK 2248761A; IDX899; IDX-899; IDX 899, Fosdevirine;Methyl (E)-(2-carbamoyl-5-chloro-1H-indol-3-yl)(3-(2-cyanovinyl)-5-methylphenyl)phosphinate;5-Chloro-3-[[3-[(E)-2-cyanoethenyl]-5-methylphenyl]-methoxyphosphoryl]-1H-indole-2-carboxamide. Grades: 95%. CAS No. 1018450-26-4. Molecular formula: C20H17ClN3O3P. Mole weight: 413.80. | |
| Fosfluconazole | Fluconazole, a water-soluble phosphate prodrug of fluconazole, is a triazole antifungal agent that is effective against most Candida strains. Uses: 14-alpha demethylase inhibitors. Synonyms: Procif; UK 292663; UK-292,663. Grades: > 95%. CAS No. 194798-83-9. Molecular formula: C13H13F2N6O4P. Mole weight: 386.26. | |
| Fosfomycin EP Impurity C (Barium Salt) | Fosfomycin EP Impurity C (Barium Salt) is an impurity of Fosfomycin, which is a broad-spectrum antibiotic used for the treatment of urinary tract infections (UTIs). Synonyms: 2-Amino-3-hydroxy-2-(hydroxymethyl)propyl Phosphate Barium Salt; Trometamol Phosphoric Acid Barium Salt; Fosfomycin EP Impurity C Barium Salt; Trometamine Phosphate Barium Salt. CAS No. 114252-50-5. Molecular formula: C4H10BaNO6P. Mole weight: 336.43. | |
| Fosfomycin Impurity D | Grades: > 95%. Molecular formula: C10H25NO11P2. Mole weight: 397.26. | |
| Fosgonimeton | Fosgonimeton is a hepatocyte growth factor receptor agonist. Synonyms: N-hexanoyl-O-phosphono-L-tyrosyl-N1-(6-amino-6-oxohexyl)-L-isoleucinamide. Grades: >98%. CAS No. 2093305-05-4. Molecular formula: C27H45N4O8P. Mole weight: 584.65. | |
| Fosinoprilat | Fosinoprilat is a metabolite of Fosinopril. Fosfenopril is a potent angiotensin converting enzyme (ACE) inhibitor. Synonyms: (4S)-4-Cyclohexyl-1-[2-[hydroxy(4-phenylbutyl)phosphinyl]acetyl]-L-proline Disodium Salt; Fosfenopril Disodium Salt; Fosinoprilat Disodium Salt; Fosinoprilic Acid Disodium Salt; SQ 27519 Disodium Salt; L-Proline, 4-cyclohexyl-1-hydroxy(4-phenylbutyl)phosphinyl. Grades: > 95%. CAS No. 95399-71-6. Molecular formula: C23H34NO5P. Mole weight: 435.50. | |
| Fosinopril sodium salt | Fosinopril Sodium is the ester prodrug of an angiotensin-converting enzyme (ACE) inhibitor. Synonyms: Monopril; Staril; Dynacil; Fosinil; Tenso Stop; Tensocardil; Sodium, Fosinopril; SQ 28,555; SQ 28555; SQ-28,555; SQ-28555; SQ28,555; SQ28555. Grades: >98%. CAS No. 88889-14-9. Molecular formula: C30H45NO7P·Na. Mole weight: 585.64. | |
| Fosnetupitant | Fosnetupitant, a piperazine derivative, has been found to be a NK1 receptor antagonist that could be used in nausea and vomiting caused by chemotherapy. It was just reported a Phase II trail in Japan. Synonyms: Fosnetupitant; T672P80L2S; Fosnetupitant; Piperazinium, 4-(5-((2-(3,5-bis(trifluoromethyl)phenyl)-2-methyl-1-oxopropyl)methylamino)-4-(2-methylphenyl)-2-pyridinyl)-1-methyl-1-((phosphonooxy)methyl)-, inner salt. Grades: 98%. CAS No. 1703748-89-3. Molecular formula: C31H35F6N4O5P. Mole weight: 688.61. | |
| Fosravuconazole | Fosravuconazole is an azole antifungal agent potentially for the treatment of fungal infections, as a water-soluble prodrug of ravuconazole that is being developed by the Drugs for Neglected Diseases Initiative (DNDi). Uses: A water-soluble prodrug of ravuconazole that is being developed by the drugs for neglected diseases initiative (dndi). Synonyms: Fosravuconazole; BEF-1224; BMS-379224; E-1224; BEF1224; BMS379224; E1224.[(2R,3R)-3-[4-(4-cyanophenyl)-1,3-thiazol-2-yl]-2-(2,4-difluorophenyl)-1-(1,2,4-triazol-1-yl)butan-2-yl]oxymethyl dihydrogen phosphate. Grades: ≥98%. CAS No. 351227-64-0. Molecular formula: C23H20F2N5O5PS. Mole weight: 547.09. | |
| Fostriecin sodium salt | Fostriecin sodium salt is a protein phosphatase types 2A (PP2A) and 4 (PP4) inhibitor (IC50 = 1.5 nM and 3 nM, respectively). It also has an inhibitory effect on topoisomerase II (IC50 = 40 μM) and protein phosphatase type 1 (PP1) (IC50 = 131 μM). Fostriecin is found in Streptomyces pulveraceous. Uses: Enzyme inhibitors. Synonyms: Fostriecin Sodium; Antibiotic CI 920 sodium salt; (6R)-5,6-Dihydro-6-[(1E,3R,4R,6R,7Z,9Z,11E)-3,6,13-trihydroxy-3-methyl-4-(phosphonooxy)-1,7,9,11-tridecatetraenyl]-2H-pyran-2-one sodium salt. Grades: ≥98% by HPLC. CAS No. 87860-39-7. Molecular formula: C19H26O9PNa. Mole weight: 452.37. | |
| Fostroxacitabine Bralpamide | Fostroxacitabine Bralpamide is an antineoplastic drug. Synonyms: (2S)-pentan-2-yl N-[(S)-{[(2S,4S)-4-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-dioxolan-2-yl]methoxy}(4-bromophenoxy)phos-phoryl]-L-alaninate; L-Alanine, N-((((2S,4S)-4-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,3-dioxolan-2-yl)methoxy)(4-bromophenoxy)phosphinyl)-, (1S)-1-methylbutyl ester; (S)-pentan-2-yl ((S)-(((2S,4S)-4-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-dioxolan-2-yl)methoxy)(4-bromophenoxy)phosphoryl)-L-alaninate; MIV-818; MIV818; MIV 818; Troxacitabine nucleotide prodrug MIV-818. CAS No. 2129993-56-0. Molecular formula: C22H30BrN4O8P. Mole weight: 589.38. | |
| FOXO4-DRI | FOXO4-DRI is a peptide acting as a specific FOXO4 blocker. It has been demonstrated to alleviate age-related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice. Grades: 95%. Molecular formula: C228H388N86O64. Mole weight: 5358.05. | |
| FPR A14 | FPR A14 is a formyl peptide receptor (FPR) agonist that potently activates neutrophils in vitro (EC50 = 42 and 630 nM for neutrophil chemotaxis and Ca2+ mobilization, respectively). Synonyms: AG 14; AG14; AG-14; 1,3-Benzodioxolane-5-carboxylic acid 4'-benzyloxy-3'-methoxybenzylidene hydrazide. Grades: ≥99% by HPLC. CAS No. 329691-12-5. Molecular formula: C23H20N2O5. Mole weight: 404.42. | |
| FQI 1 | FQI 1 is a cell-permeable and reversible inhibitor of α-globin transcription factor CP2 (LSF; IC50 = 2.1 μM) and an antiproliferative. FQI 1 induces apoptosis in LSF-overexpressing cells, including Hepatocellular carcinoma (HCC cells). FQI 1 acts via inhibiting LSF-DNA binding. Uses: Antiproliferative. Synonyms: FQI 1; FQI1; FQI-1; 8-(2-ethoxyphenyl)-7,8-dihydro[1,3]dioxolo[4,5-g]quinolin-6(5H)-one; 8-(2-Ethoxy-phenyl)-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]quinolin-6-one. Grades: 99%. CAS No. 599151-35-6. Molecular formula: C18H17NO4. Mole weight: 311.33. | |
| FR 113680 | FR 113680 is a novel tripeptide substance P antagonist with NK1 receptor selectivity originated by Fujisawa for the treatment of Asthma. But no development are reported yet. Uses: Asthma. Synonyms: FR 113680; FR113680; FR-113680; Ac-Thr-trp(cho)-phe-N-mebzl. Ac-Thr-trp(cho)-phe-N-mebzl;N-acetyl-L-threonyl-1-formyl-D-tryptophyl-N-methyl-N-(phenylmethyl)-L-Phenylalaninamide. Grades: 98%. CAS No. 126088-92-4. Molecular formula: C35H39N5O6. Mole weight: 625.72. | |
| FR 121196 | FR 121196 is a potential antidementia drug originated by Fujisawa. Mechanism of Action is not undefined. FR 121196 can ameliorate the impaired memory of rat in the Morris water maze. No development was reported for Cognition disorders in Japan. Uses: Cognition disorders. Synonyms: FR 121196; FR 121196; FR 121196. N-(4-acetylpiperazin-1-yl)-4-fluorobenzenesulfonamide. Grades: 98%. CAS No. 133920-65-7. Molecular formula: C12H16FN3O3S. Mole weight: 301.34. | |
| FR-168888 | FR-168888, a guanidine compound, has been found to be a sodium hydrogen antiporter inhibitor that was once studied in myocardial ischaemia therapy. Synonyms: FR-168888; FR 168888; FR168888; Benzamide, N-(aminoiminomethyl)-3-(hydroxymethyl)-5-(1H-pyrrol-1-yl)-, methanesulfonate (1:1). Grades: 98%. CAS No. 168620-46-0. Molecular formula: C14H18N4O5S. Mole weight: 354.38. | |
| FR-168888 Free Base | The free base of FR-168888, a guanidine compound, has been found to be a sodium hydrogen antiporter inhibitor that was once studied in myocardial ischaemia therapy. Synonyms: FR-168888 free base; FR 168888 free base; FR168888 free base; SCHEMBL1388039; SCHEMBL8300855; Benzamide, N-(aminoiminomethyl)-3-(hydroxymethyl)-5-(1H-pyrrol-1-yl)-. Grades: 98%. CAS No. 168620-45-9. Molecular formula: C13H14N4O2. Mole weight: 258.28. | |
| FR-181074 | FR-181074 may be a bio-active chemical to treat Male Sexual Dysfunction. Synonyms: 1-[(2-chlorophenyl)methyl]-3-(2-methylpropanoyl)-2-propylindole-6-carboxamide; FR-181074; FR181074; FR 181074; UNII-D3C5RV093V. Grades: >98%. CAS No. 184147-65-7. Molecular formula: C23H25ClN2O2. Mole weight: 396.91. | |
| FR-181157 | FR-181157, an oxazol derivative, has been found to be a prostaglandin mimetic and could have potential biological activities as a IP receptor agonist. Synonyms: FR-181157; FR 181157; FR181157; FR-181157 Free Base. (S)-FR-181157; SCHEMBL8057380; sodium;2-[3-[[(1S)-2-(4,5-diphenyl-1,3-oxazol-2-yl)cyclohex-2-en-1-yl]methyl]phenoxy]acetate. Grades: 98%. CAS No. 171046-15-4. Molecular formula: C30H26NNaO4. Mole weight: 487.52. | |
| FR-181877 | FR-181877, an oxopyridazin derivative, has been found to be a nonprostanoid PGI2 agonist and could restrain the aggregation of human platelets induced by ADP. IC50: 0.081μM. Synonyms: FR-181877; FR 181877; FR181877. (-)-FR-181877; 2-[[(6S)-6-[(3-benzhydryl-6-oxopyridazin-1-yl)methyl]-5,6,7,8-tetrahydronaphthalen-1-yl]oxy]acetic acid. Grades: 98%. CAS No. 172936-99-1. Molecular formula: C30H28N2O4. Mole weight: 480.56. | |
| FR-182024 | FR-182024, an azabicyclo derivative, has been found to have potential activity as an anti-Helicobacter pylori agent and was once stuied against helicobacter infections. Synonyms: FR-182024; FR 182024; FR182024. 9031SV3FWE; (6R,7R)-3-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]-8-oxo-7-[(2-phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid. Grades: 98%. CAS No. 179034-83-4. Molecular formula: C18H16N4O4S3. Mole weight: 448.53. | |
| FR-182980 | FR-182980, a pyridine derivative, has been found to be a sterol O-acyltransferase inhibitor and was once studied in hypercholesterolaemia. Synonyms: FR-182980; FR182980; FR 182980; 1-cycloheptyl-1-[[4-(4-fluorophenoxy)phenyl]methyl]-3-[6-methyl-2,4-bis(methylsulfanyl)pyridin-3-yl]urea. Grades: 98%. CAS No. 179054-51-4. Molecular formula: C29H34FN3O2S2. Mole weight: 539.73. | |
| FR-186054 | FR-186054, a pyridine derivative, has been found to be a sterol O-acyltransferase inhibitor and was once studied in hyperlipidaemia. Synonyms: FR-186054; FR 186054; FR186054; 1-benzyl-3-[6-methyl-2,4-bis(methylsulfanyl)pyridin-3-yl]-1-[[3-(1H-pyrazol-5-yl)phenyl]methyl]urea. Grades: 98%. CAS No. 179053-90-8. Molecular formula: C26H27N5OS2. Mole weight: 489.66. | |
| FR-190809 | FR-190809 is a potent and orally efficacious ACAT inhibitor potentially for the treatment of Lipoprotein Disorders. Synonyms: 1-cycloheptyl-1-[[4-(4-fluorophenoxy)phenyl]methyl]-3-[6-methyl-2,4-bis(methylsulfonyl)pyridin-3-yl]urea; FR-190809; FR 190809; FR190809.N-cycloheptyl-N-(4-(4-fluorophenoxy)-benzyl)-N'-(2,4-bis(methylsulfonyl)-6-methylpyridin-3-yl)urea. Grades: >98%. CAS No. 215589-63-2. Molecular formula: C29H34FN3O6S2. Mole weight: 603.73. | |
| FR-193262 | FR-193262 is a designed prostacyclin mimetic without PG skeleton which exhibits potent PGI2 agonistic activity with good selectivity for IP receptor and bioavailability. Synonyms: FR-193262; FR 193262; FR193262; sodium;2-[[(5R)-5-[(2R)-2-(4,5-diphenyl-1,3-oxazol-2-yl)pyrrolidin-1-yl]-5,6,7,8-tetrahydronaphthalen-1-yl]oxy]acetate; FR-193262; 187992-22-9(FR-193262); 314289-63-9 (FR-193262 Free Base). Grades: >98%. CAS No. 187992-22-9. Molecular formula: C31H29N2NaO4. Mole weight: 516.56. | |
| FR-193262 Free base | A bio-active organic chemical. Uses: A bio-active organic chemical. Synonyms: FR-193262; FR 193262; FR193262; 2-[[(5R)-5-[(2R)-2-(4,5-diphenyl-1,3-oxazol-2-yl)pyrrolidin-1-yl]-5,6,7,8-tetrahydronaphthalen-1-yl]oxy]acetic acid. Grades: ≥98%. CAS No. 314289-63-9. Molecular formula: C31H30N2O4. Mole weight: 494.59. | |
| FR-202306 | FR-202306 is a synthetic peptide deformylase (PDF) inhibitor. Uses: Peptide deformylase (pdf) inhibitor. Synonyms: FR-202306; FR 202306; FR202306. 3-methoxy-7-methyl-1,3-dihydro-2-benzofuran-4,5,6-triol. Grades: ≥98%. CAS No. 342785-41-5. Molecular formula: C10H12O5. Mole weight: 212.20. | |
| FR-217840 | FR-217840 is a matrix metalloproteinase inhibitor. It can suppress joint destruction. FR217840 may have potential as a novel anti-rheumatic drug. Uses: Anti-rheumatic agent. Synonyms: FR-217840; FR217840; FR 217840. (2S)-1-((5-(4-fluorophenyl)-2-thienyl)sulfonyl)-N-hydroxy-4-(methylsulfonyl)-2-Piperazinecarboxamide. Grades: 98%. CAS No. 848444-16-6. Molecular formula: C16H18FN3O6S3. Mole weight: 463.52. | |
| FR-218944 | FR-218944 is a vasopressin antagonist compound. Synonyms: methanesulfonic acid;2-methoxy-N-(2-methyl-1H-benzimidazol-4-yl)-4-(2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl)benzamide; FR-218944; FR 218944; FR218944. Grades: >98%. CAS No. 233264-02-3. Molecular formula: C28H30N4O6S. Mole weight: 550.63. | |
| FR295389 free base | FR295389 free base is a new cephalosporin. It shows effective in vitro antibacterial activity against metallo-beta-lactamase (MBL)-producers. Uses: Fr295389 free base has effective antibacterial activity. Synonyms: FR-295389 free base; FR 295389 free base; FR295389 free base; (6R,7R)-3-[[7-[3-aminopropyl(carbamimidoyl)amino]-2,3-dihydroimidazo[1,2-b]pyrazol-5-yl]methyl]-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(2-carboxypropan-2-yloxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid. Grades: >98 %. CAS No. 1019207-71-6. Molecular formula: C25H33N13O7S2. Mole weight: 691.74. | |
| FR295389 sulfuric acid | FR295389 sulfuric acid is the sulfate form of FR295389, which is a new cephalosporin. It has effective in vitro antibacterial activity against metallo-beta-lactamase (MBL)-producers. Uses: Fr295389 sulfuric acid has effective antibacterial activity. Synonyms: FR-295389 sulfuric acid; FR 295389 sulfuric acid; FR295389 sulfuric acid; (6R,7R)-3-[[7-[3-aminopropyl(carbamimidoyl)amino]-2,3-dihydroimidazo[1,2-b]pyrazol-5-yl]methyl]-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(2-carboxypropan-2-yloxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sulfuric acid. Grades: >98 %. CAS No. 1019207-72-7. Molecular formula: C25H35N13O11S3. Mole weight: 789.81. | |
| FR-64822 | FR-64822 is a novel non-opioid antinociceptive compound. It has antinociceptive activities in a variety of assays in mice and rats. It also has a strong antinociceptive activity in the acetic acid writhing test. Uses: Fr-64822 has antinociceptive activities. Synonyms: FR 64822; FR64822; FR-64822. N-(4-Pyridylcarbamoyl)amino 1,2,3,6-tetrahydropyridine;1-(3,6-dihydro-2H-pyridin-1-yl)-3-pyridin-4-ylurea;FR64822. Grades: >98 %. CAS No. 102671-35-2. Molecular formula: C11H14N4O. Mole weight: 218.26. | |
| FR 75513 | FR 75513 is a 1,1'-biphenyl-2,6-dicarboxylic acid diester compound with inhibitory activity on guinea-pig detrusor muscle contraction at electrical field stimulation in vitro. IC 50 value is 3.3 x 10(-6) g/ml. Synonyms: FR 75513; FR75513; FR-75513. 3-O-methyl 1-O-propan-2-yl 4-hydroxy-6-methyl-2-(2-nitrophenyl)benzene-1,3-dicarboxylate. Grades: 98%. CAS No. 127975-78-4. Molecular formula: C19H19NO7. Mole weight: 373.36. | |
| FR 76830 | This molecular is developed as a novel bradycardiac agent through organic synthesis. Uses: Bradycardiac agent. Synonyms: FR 76830; FR-76830; FR76830. 2-methyl-N-(4-morpholinylethyl)-4-(3-nitrophenyl)-6-phenyl- 3-Pyridinecarboxamide. Grades: 98%. CAS No. 113243-75-7. Molecular formula: C25H26N4O4. Mole weight: 446.5. | |
| FR-78844 | FR-78844 is used as a bone resorption antagonist. Uses: Fr-78844 is used as a bone resorption antagonist. Synonyms: FR 78844; FR78844; FR-78844; Disodium phenylthiocarbamoyl methyl enediphosphonate; (2- (Phenylamino) -2-thioxoethylidene) bisphosphonic acid disodium salt;Disodium [2-anilino-1-[hydroxy(oxido)phosphoryl]-2-sulfanylideneethyl]-hydroxyphosphinate; FR78844; Phosphonic acid, (2-(phenylamino)-2-thioxoethylidene)bis-, disodium salt. Grades: >98%. CAS No. 112856-39-0. Molecular formula: C8H9NNa2O6P2S. Mole weight: 355.15. | |
| FR900098 sodium salt | FR900098 is a derivative of fosmidomycin that displays antimalarial activity. FR900098 is an inhibitor of DOXP reductoisomerase, a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis. Synonyms: (3-(Acetylhydroxyamino)propyl)-phosphonic acid, monosodium salt; BRN 2096083; P-[3-(Acetylhydroxyamino)propyl]-phosphonic acid, monosodium salt. Grades: ≥95%. CAS No. 73226-73-0. Molecular formula: C5H11NO5P·Na. Mole weight: 219.1. | |
| FRAX1036 | FRAX1036 is a highly selective PAK1 inhibitor that remarkably altered signaling to cytoskeletal-associated proteins. In vitro and in vivo tests with FRAX-1036 have shown that the small-molecule inhibitor can both deter proliferation in ovarian cancer cell. Synonyms: 6-[2-chloro-4-(6-methylpyrazin-2-yl)phenyl]-8-ethyl-2-[2-(1-methylpiperidin-4-yl)ethylamino]pyrido[2,3-d]pyrimidin-7-oneFRAX1036; FRAX-1036; FRAX 1036SCHEMBL14928919CS-5585; HY-19538; CS 5585; HY 19538; CS5585; HY19538. CAS No. 1432908-05-8. Molecular formula: C28H32ClN7O. Mole weight: 518.06. | |
| FRAX486 | FRAX486, an effective PAK inhibitor, could improve epileptic seizures and sorts of other abnormal behaviors. Uses: Frax486 is an effective pak inhibitor that could improve epileptic seizures and sorts of other abnormal behaviors. Synonyms: FRAX486; FRAX-486; FRAX 486; 6-(2,4-dichlorophenyl)-8-ethyl-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one; C25H23Cl2FN6O; FRAX 486. Grades: 98%. CAS No. 1232030-35-1. Molecular formula: C25H23Cl2FN6O. Mole weight: 513.39. | |
| FRAX597 | FRAX597 is a potent, ATP-competitive inhibitor of group I PAKs with IC50 of 8 nM, 13 nM, and 19 nM for PAK1, PAK2, and PAK3, respectively. Synonyms: FRAX597; FRAX-597; FRAX 597. Grades: >98%. CAS No. 1286739-19-2. Molecular formula: C29H28ClN7OS. Mole weight: 558.10. | |
| Frenlosirsen | Frenlosirsen is an interferon regulatory factor 4 (IRF4) synthesis reducer, with antineoplastic properties. Synonyms: all-P-ambo-2'-O,4'-C-[(1S)-ethane-1,1-diyl]-P-thioadenylyl-(3'?5')-2'-O,4'-C-[(1S)-ethane-1,1-diyl]-P-thioguanylyl-(3'?5')-P-thiothymidylyl-(3'?5')-P-thiothymidylyl-(3'?5')-2'-deoxy-P-thioguanylyl-(3'?5')-P-thiothymidylyl-(3'?5')-2'-deoxy-P-thioadenylyl-(3'?5')-2'-deoxy-P-thioadenylyl-(3'?5')-2'-deoxy-P-thioadenylyl-(3'?5')-P-thiothymidylyl-(3'?5')-2'-deoxy-P-thioguanylyl-(3'?5')-2'-O-(2-methoxyethyl)-P-thioadenylyl-(3'?5')-2'-O-(2-methoxyethyl)-P-thioguanylyl-(3'?5')-2'-O-(2-methoxyethyl)-5-methyl-P-thiouridylyl-(3'?5')-2'-O,4'-C-[(1S)-ethane-1,1-diyl]-5-methyl-P-thiocytidylyl-(3'?5')-2'-O,4'-C-[(1S)-ethane-1,1-diyl]guanosine; DNA, d(P-thio)((2',5'-anhydro-6'-deoxy-4'-C-(hydroxymethyl)-alpha-L-mannofurano)A-(3'->4')-(2',5'-anhydro-6'-deoxy-4'-C-(hydroxymethyl)-alpha-L-mannofurano)G-T-T-G-T-A-A-A-T-G-(2'-O-(2-methoxyethyl))rA-(2'-O-(2-methoxyethyl))rG-(2'-O-(2-methoxyethyl))m5rU-(3'->4')-(2',5'-anhydro-6'-deoxy-4'-C-(hydroxymethyl)-alpha-L-mannofurano)m5C-(3'->4')-(2',5'-anhydro-6'-deoxy-4'-C-(hydroxymethyl)-alpha-L-mannofurano)G). CAS No. 2304711-81-5. Molecular formula: C177H226N63O89P15S15. Mole weight: 5605.71. | |
| FTase Inhibitor I | FTase inhibitor I is a potent and selective farnesyltransferase (FTase) inhibitor with an IC50 of 21 nM, which is 30-fold higher for FTase over geranylgeranyl transferase (GGTase; IC50 = 790 nM). Synonyms: Farnesyltransferase Inhibitor I; B581; N-[(2S)-2-[[(2R)-2-amino-3-mercaptopropyl]amino]-3-methylbutyl]-L-phenylalanyl-L-methionine. Grades: ≥95%. CAS No. 149759-96-6. Molecular formula: C22H38N4O3S2. Mole weight: 470.69. | |
| FTase Inhibitor II | FTase Inhibitor II is a cell-permeable analog of farnesyl pyrophosphate (FPP) that potently inhibits FTase with an IC50 of 50-75 nM, and it does not inhibit geranylgeranyl transferase at similar concentrations (IC50 > 100 μM). FTase Inhibitor II is a possible cancer therapeutic agent. Synonyms: Farnesyltransferase Inhibitor II; FTI-II; N-[4-[[(2R)-2-amino-3-mercapto-1-oxopropyl]amino]benzoyl]-L-methionine. Grades: ≥80%. CAS No. 156707-43-6. Molecular formula: C15H21N3O4S2. Mole weight: 371.47. | |
| FTBMT | FTBMT is a novel and selective GPR52 agonist (EC50 = 75 nM, Emax = 122%). FTBMT displays antipsychotic and procognitive properties without causing catalepsy in rodents. Synonyms: 4-[3-[[3-Fluoro-5-(trifluoromethyl)phenyl]methyl]-5-methyl-1H-1,2,4-triazol-1-yl]-2-methylbenzamide. Grades: ≥98% by HPLC. CAS No. 1358575-02-6. Molecular formula: C19H16F4N4O. Mole weight: 392.35. | |
| FTI 276 trifluoroacetate salt | FTI 276 is a Ras CAAX peptidomimetic, a selective inhibitor of farnesyltransferase (FTase) with > 100-fold selectivity over geranylgeranyltransferase I (GGTase I) (IC50 = 0.5 and 50 nM, respectively). It exhibits an inhibitory effect on growth of human lung carcinoma expressing oncogenic K-Ras in nude mice. Synonyms: FTI 276 trifluoroacetate salt; FTI276 trifluoroacetate salt; FTI-276 trifluoroacetate salt; N-[4-[2(R)-Amino-3-mercaptopropyl]amino-2-phenylbenzoyl]methionine trifluoroacetate salt. Grades: ≥95% by HPLC. CAS No. 1217471-51-6. Molecular formula: C21H27N3O3S2.C2HF3O2. Mole weight: 547.61. | |
| FTI 277 trifluoroacetate salt | FTI 277 is a prodrug form of FTI 276 that inhibits farnesyltransferase (FTase) (IC50 = 0.5 nM) with antiproliferative activity. It potently inhibits H-Ras and K-Ras processing in whole cells (IC50 = 0.1 and 10 μM, respectively) and disrupts constitutive H-Ras-specific activation of MAPK. Synonyms: FTI 277 trifluoroacetate salt; FTI277 trifluoroacetate salt; FTI-277 trifluoroacetate salt; N-[4-[2(R)-Amino-3-mercaptopropyl]amino-2-phenylbenzoyl]methionine methyl ester trifluoroacetate salt. Grades: ≥95% by HPLC. CAS No. 1217447-06-7. Molecular formula: C22H29N3O3S2.C2HF3O2. Mole weight: 561.64. | |
| FTY720 phenoxy-biotin | FTY720 is a potent agonist at four of the five sphingosine-1-phosphate (S1P) receptors. Biotin-FTY720 is a biotin-tagged analog of FTY720. The hydroxy methyl side chain of FTY720 that is targeted for phosphorylation by sphingosine kinases is retained in this analog, which means that it would likewise be phosphorylated in vivo. Synonyms: 2-amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol-N-biotinoyl-1,5-diampentane. Grades: ≥95%. Molecular formula: C27H44N4O5S·HCl. Mole weight: 573.2. | |
| FTY720 Phosphate | FTY720 is a derivative of ISP-1 (myriocin). FTY720 phosphate is a potent agonist at four of the sphingosine-1-phosphate (S1P) receptors (S1P1, S1P3, S1P4, and S1P5, IC50 values = 0.2-6 nM). Synonyms: FTY720P; 2-amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol, 1-(dihydrogen phosphate). Grades: ≥98%. CAS No. 402615-91-2. Molecular formula: C19H34NO5P. Mole weight: 387.5. | |
| FTY720 (R)-Phosphate | FTY720 is a potent agonist at four of the five sphingosine-1-phosphate (S1P) receptors. FTY720 (R)-phosphate is one of the stereoisomers of FTY720-phosphate. Synonyms: (2R)-amino-2-[2-(4-octylphenyl)ethyl]-1-(dihydrogen phosphate)-1,3-propanediol. Grades: ≥98%. CAS No. 402616-23-3. Molecular formula: C19H34NO5P. Mole weight: 387.5. | |
| FTY720 (S)-Phosphate | FTY720 is a potent agonist at four of the five sphingosine-1-phosphate (S1P) receptors. FTY720 (S)-phosphate is the single stereoisomer of FTY720. FTY720 (S)-phosphate exhibits Ki values of 2.1, 5.9, 23, and 2.2 nM for S1P1,3,4,5, respectively, whereas the R enantiomer binds with 5 to 130-fold lower affinity. Synonyms: (S)-FTY 720P; (2S)-amino-2-[2-(4-octylphenyl)ethyl]-1-(dihydrogen phosphate)-1,3-propanediol. Grades: ≥98%. CAS No. 402616-26-6. Molecular formula: C19H34NO5P. Mole weight: 387.5. | |
| Fumarate hydratase-IN-1 | Fumarate hydratase-IN-1, an enzyme of the TCA cycle, identified as the principal pharmacological target. CAS No. 1644060-37-6. Molecular formula: C27H30N2O4. Mole weight: 446.54. | |
| Furaltadone Hydrochloride | Furaltadone HCl is an antibacterial and has distinct curative effect in the treatment of coccidiosis. Grades: >98%. CAS No. 3759-92-0. Molecular formula: C13H16N4O6.HCl. Mole weight: 360.75. | |
| Furamidine dihydrochloride | Furamidine dihydrochloride is a protein arginine methyltransferase 1 (PRMT1) inhibitor (IC50 = 9.4 μM) in the class of antimicrobial and antiparasitic agents. It was shown to inhibit cell proliferation in leukemia cell lines. Synonyms: 4,4'-(2,5-Furandiyl)bis-benzenecarboximidamide dihydrochloride. Grades: ≥98% by HPLC. CAS No. 55368-40-6. Molecular formula: C18H16N4O.2HCl. Mole weight: 377.27. | |
| Furanone C-30 | Furanone C-30 is a synthetic furanone bacterial quorum sensing inhibitor that inhibits virulence factor expression in Pseudomonas aeruginosa and increases bacterial susceptibility to antibiotics in vitro. Synonyms: (5Z)-4-Bromo-5-(bromomethylene)-2(5H)-furanone. Grades: ≥98%. CAS No. 247167-54-0. Molecular formula: C5H2Br2O2. Mole weight: 253.88. | |
| Furegrelate sodium salt | Furegrelate is a selective and potent inhibitor of thromboxane synthase with an IC50 value of 15 nM for human platelet microsomal thromboxane synthase. Synonyms: U-63557A; 5-(3-pyridinylmethyl)-2-benzofurancarboxylic acid, sodium salt. Grades: ≥99%. CAS No. 85666-17-7. Molecular formula: C15H10NO3·Na. Mole weight: 275.2. | |
| Furfuryl acrylate | Synonyms: furan-2-ylmethyl acrylate. Grades: 95%. CAS No. 10525-17-4. Molecular formula: C8H8O3. Mole weight: 152.15. | |
| Furilazole | Furilazole, an oxazole derivative, is a herbicide commonly used for gramineous crops. Uses: Furilazole is a herbicide commonly used for gramineous crops. Synonyms: (RS)-3-Dichloroacetyl-5-(2-furanyl)-2,2-dimethyl-1,3-oxazolidine. Grades: 98%. CAS No. 121776-33-8. Molecular formula: C11H13Cl2NO3. Mole weight: 278.13. | |
| Furosemide Impurity C | Furosemide Impurity C is a metabolite of Furosemide. Furosemide is a medication used to treat fluid build-up and swelling caused by congestive heart failure, liver cirrhosis, or kidney disease. Synonyms: 4-Chloro-5-sulfamoylanthranilic acid; 4-Chloro-5-sulfamylanthranilic acid; Desfurylmethylfurosemide; Saluamine; 4-Chloro-5-sulfamoyl-anthranilic Acid; 2-Amino-4-chloro-5-sulfamoylbenzoic Acid; 4-Chloro-5-sulfamoylanthranilic Acid. Grades: > 95%. CAS No. 3086-91-7. Molecular formula: C7H7ClN2O4S. Mole weight: 250.66. | |
| Furosemide Impurity D | Furosemide Impurity D is a Furosemide impurity. Furosemide is a medication used to treat fluid build-up and swelling caused by congestive heart failure, liver cirrhosis, or kidney disease. Synonyms: 4-Deschloro-4-(2-furanylmethyl)amino Furosemide; 5-(Aminosulfonyl)-2,4-bis[(2-furanylmethyl)amino]benzoic Acid. Grades: > 95%. CAS No. 5046-19-5. Molecular formula: C17H17N3O6S. Mole weight: 391.41. | |
| Futibatinib | Futibatinib is an orally bioavailable, selective and irreversible inhibitor of fibroblast growth factor receptors (FGFRs), displaying antineoplastic activity. It inhibits FGFR-mediated signal transduction and tumor cell proliferation. Synonyms: 1-[(3S)-3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]-1-pyrazolo[3,4-d]pyrimidinyl]-1-pyrrolidinyl]-2-propen-1-one; 1-[(3S)-3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]pyrazolo[3,4-d]pyrimidin-1-yl]pyrrolidin-1-yl]prop-2-en-1-one. Grades: ≥ 98 %. CAS No. 1448169-71-8. Molecular formula: C22H22N6O3. Mole weight: 418.45. | |
Our database is helping our users find suppliers everyday.
