BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Entospletinib | Entospletinib (GS-9973) is an orally bioavailable, selective Syk inhibitor with IC50 of 7.7 nM. Phase 2. Synonyms: GS9973; GS 9973; GS-9973. Grades: >98%. CAS No. 1229208-44-9. Molecular formula: C23H21N7O. Mole weight: 411.46. |  |
| Enzalutamide | Enzalutamide is an androgen-receptor (AR) antagonist with IC50 of 36 nM. It inhibits the activity of prostate cancer cell Ars, which over expressed in prostate cancer. Uses: Potential antineoplastic agent. Synonyms: MDV3100; MDV 3100; MDV-3100; 4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide; Benzamide, 4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro-N-methyl-; 4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro-N-methylbenzamide; S-Enzalutamide; Xtandi. Grades: >98%. CAS No. 915087-33-1. Molecular formula: C21H16F4N4O2S. Mole weight: 464.44. | |
| Enzalutamide Carboxylic Acid | Enzalutamide Carboxylic Acid is a metabolite of Enzalutamide. Enzalutamide Carboxylic Acid is used as hormone therapies to prevent androgen-fuled growth of castrate-resistant prostate cancer. Synonyms: 4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro-benzoic Acid. CAS No. 1242137-15-0. Molecular formula: C20H13F4N3O3S. Mole weight: 451.4. | |
| Enzastaurin | Enzastaurin is a protein kinase C beta inhibitor with 6- to 20-fold selectivity against PKCα, PKCγ and PKC&epsilon. Binding to the ATP-binding site, enzastaurin selectively inhibits protein kinase C beta, an enzyme involved in the induction of vascular endothelial growth factor (VEGF)-stimulated neo-angiogenesis. This agent may decrease tumor blood supply and so tumor burden. Synonyms: 3-(1-Methyl-1H-indol-3-yl)-4-(1-(1-(pyridin-2-ylmethyl)piperidin-4-yl)-1H-indol-3-yl)-1H-pyrrole-2,5-dione; LY-317615. CAS No. 170364-57-5. Molecular formula: C32H29N5O2. Mole weight: 515.617. | |
| EP Chlorpheniramine Maleate Impurity A (2HCl salt form) | An impurity of Chlorpheniramine. Chlorpheniramine is an antihistamine used to prevent symptoms of allergy. It acts via inhibiting histamine produced during anaphylaxis. Synonyms: 2-(4-Chlorophenyl)-4-(dimethylamino)-2-(2-(dimethylamino)ethyl)butanenitrile; 2-(4-Chlorophenyl)-4-(dimethylamino)-2-[2-(dimethylamino)ethyl]butanenitrile dihydrochloride. Grades: 95%. Molecular formula: C16H26Cl3N3. Mole weight: 366.761. | |
| Epelsiban | Epelsiban is an oxytocin receptor antagonist under the developement of GlaxoSmithKline. It has high affinity for the oxytocin receptor (Ki = 0.13 nM) with >31,000-fold selectivity over the related vasopressin receptors. No development was reported about Phase II clinical tirals for the treatment of premature ejaculation. Uses: Premature ejaculation. Synonyms: GSK-557296; GSK 557296; GSK557296; GSK-557,296-B;(3R,6R)-6-((S)-sec-butyl)-3-(2,3-dihydro-1H-inden-2-yl)-1-((R)-1-(2,6-dimethylpyridin-3-yl)-2-morpholino-2-oxoethyl)piperazine-2,5-dione;1159097-48-9(besylate). Grades: 98%. CAS No. 872599-83-2. Molecular formula: C30H38N4O4. Mole weight: 518.65. | |
| Epelsiban besylate | This active molecular, also known as GSK-557296B is a selective, sub-nanomolar (Ki=0.13 nM) oxytocin receptor antagonist with more than 30000-fold selectivity over the related vasopressin receptors. GlaxoSmithKline developed it for the treatment of premature ejaculation in men and also as an agent to enhance embryo or blastocyst implantation in women undergoing embryo or blastocyst transfer associated with in vitro fertilization. In Jul 1st 2016, Phase-II clinical trials in Adenomyosis in USA was on going. In Jun 13th 2016, GlaxoSmithKline terminated phase I trial in Infertility (In volunteers) in USA. Uses: Adenomyosis;infertility; premature ejaculation. Synonyms: (3R,6R)-3-(2,3-Dihydro-1H-inden-2-yl)-1-((1R)-1-(2,6-dimethylpyridin-3-yl)-2- (morpholin-4-yl)-2-oxoethyl)-6-((1S)-1-methylpropyl)piperazine-2,5-dione monobenzenesulfonate,UNII-H629P9T4UN; UNII-H629P9T4UN; GSK557296B; GSK-557296B; 872599-83-2(free base). Grades: 98%. CAS No. 1159097-48-9. Molecular formula: C36H44N4O7S. Mole weight: 676.83. | |
| Epetirimod | Epetirimod is a small-molecule immune-response modifier intended for the topical treatment of cervical human papilloma virus (HPV) infection and cervical dysplasia. Synonyms: S-30563; S 30563; S30563; 1-(2-methylpropyl)imidazo[4,5-c][1,5]naphthyridin-4-amine; Epetirimod. Grades: >98%. CAS No. 227318-71-0. Molecular formula: C13H15N5. Mole weight: 241.298. | |
| Epetraborole HCl | This active molecular is a selective leucyl-tRNA synthetase inhibitor under the development of Anacor Pharmaceuticals and GlaxoSmithKline as a novel boron-containing antibiotic. Epetraborole was applicated in treatment of infections caused by multidrug-resistant Gram-negative pathogens. All Clostridium perfringens strains had Epetraborole MICs of >32 μg/ml. In Oct 2012, Phase-II for Urinary tract infections in Russia was discontinued. In Mar 2013, Phase-II for Gram-negative infections in USA was Suspended. Uses: Urinary tract infections;gram-negative infections. Synonyms: UNII-MM0NZY12FA; MM0NZY12FA;SCHEMBL1980656; CHEMBL3527377;3-[[(3S)-3-(aminomethyl)-1-hydroxy-3H-2,1-benzoxaborol-7-yl]oxy]propan-1-ol;hydrochloride; AN-3365; GSK-052; AN 3365; GSK 052; AN3365; GSK052. Grades: 98%. CAS No. 1234563-16-6. Molecular formula: C11H17BClNO4. Mole weight: 373.52. | |
| Epibatidine | (±)-Epibatidine is a potent nicotinic agonist (Ki = 0.02 and 233 nM for α4β2 and α7 nicotinic receptors, respectively). Uses: Analgesic. Synonyms: Epibatidine; (±)-exo-2-(6-Chloro-3-pyridinyl)-7-azabicyclo[2.2.1.]heptane. CAS No. 140111-52-0. Molecular formula: C11H13ClN2. Mole weight: 208.69. | |
| (±)-Epibatidine | High affinity nicotinic agonist (Ki values are 0.02 and 233 nM for α4β2 and α7 nicotinic receptors respectively). Analgesic. Uses: Analgesics, non-narcotic. Synonyms: (±)-exo-2-(6-Chloro-3-pyridinyl)-7-azabicyclo[2.2.1.]heptane; 2-(6-chloropyridin-3-yl)-7-azabicyclo[2.2.1]heptane. Grades: ≥99%. CAS No. 148152-66-3. Molecular formula: C11H13ClN2. Mole weight: 208.69. | |
| (-)-Epibatidine dihydrochloride | (-)-Epibatidine dihydrochloride is a highly potent nicotinic agonist and (-)-Enantiomer of (±)-Epibatidine dihydrochloride. Synonyms: (3S)-3-(6-chloropyridin-3-yl)-7-azabicyclo[2.2.1]heptane dihydrochloride. Grades: 99%. CAS No. 152378-30-8. Molecular formula: C11H13ClN2.2HCl. Mole weight: 281.61. | |
| (+)-Epibatidine dihydrochloride | (+)-Epibatidine dihydrochloride is a highly potent nicotinic agonist and (+)-Enantiomer of (±)-Epibatidine dihydrochloride. Synonyms: 3-(6-chloropyridin-3-yl)-7-azabicyclo[2.2.1]heptane dihydrochloride. Grades: 99%. CAS No. 166374-43-2. Molecular formula: C11H13ClN2.2HCl. Mole weight: 281.61. | |
| (±)-Epibatidine dihydrochloride | (±)-Epibatidine dihydrochloride is a highly potent nicotinic agonist used as a non-narcotic analgesic. Uses: Analgesic. Synonyms: (1R,3S,4S)-3-(6-chloropyridin-3-yl)-7-azabicyclo[2.2.1]heptane dihydrochloride. Grades: 99%. CAS No. 162885-01-0. Molecular formula: C11H13ClN2.2HCl. Mole weight: 281.61. | |
| Epi-Calcitriol | Impurity B of Calcitriol is the hormonally active form of vitamin D, and Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR), which inhibits in vivo and in vitro cell proliferation in a wide range of cells including breast, prostate, colon, skin and brain carcinomas and myeloid leukemia cells. Synonyms: 1β,25-Dihydroxyvitamin-D3; 1-Epicalcitriol. Grades: >98%. CAS No. 66791-71-7. Molecular formula: C27H44O3. Mole weight: 416.64. | |
| Epigallocatechin 3-O-(3-O-Methyl)-Gallate | (-)-EGCG-3''-O-Me is a compound of the flavonoid class found in the leaves of Camellia sinensis. It exhibits antioxidative, antiallergic and anti-inflammatory effects. Synonyms: Epigallocatechin 3-O-(3-O-methyl)gallate; [(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4-dihydroxy-5-methoxybenzoate. Grades: >98%. CAS No. 83104-87-4. Molecular formula: C23H20O11. Mole weight: 472.402. | |
| Epigomisin O | Epigomisin O is a lignan isolated from the fruits of Schizandra chinensis. Synonyms: Epigomisin O; 73036-31-4; UNII-BC1N1HR50PBC1N1HR50P(8S, 9S, 10S)-3, 4, 5, 19-tetramethoxy-9, 10-dimethyl-15, 17-dioxatetracyclo[10.7.0.02, 7.014, 18]nonadeca-1(19), 2, 4, 6, 12, 14(18)-hexaen-8-ol. Grades: >98%. CAS No. 73036-31-4. Molecular formula: C23H28O7. Mole weight: 416.47. | |
| Epimagnolin A | Epimagnolin A is a lignan isolated from the dried flower buds of Magnolia biondii Pamp. Synonyms: (3S,3aR,6R,6aR)-3-(3,4-dimethoxyphenyl)-6-(3,4,5-trimethoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan. Grades: >98%. CAS No. 41689-51-4. Molecular formula: C23H28O7. Mole weight: 416.47. | |
| Eplerenone EP Impurity C | An impurity of Eplerenone. Eplerenone is a potassium-sparing diuretic that selectively blocks aldosterone activation of the mineralcorticoid receptor, demonstrating little activity towards other steroid receptors. Synonyms: Δ9,11-7β-Eplerenone; (2'R,7R,8R,10S,13S,14S)-Methyl 10,13-dimethyl-3,5'-dioxo-1,2,3,4',5',6,7,8,10,12,13,14,15,16-tetradecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-7-carboxylate; (7a,17a)-17-Hydroxy-3-oxo-pregna-4,9(11)-diene-7,21-dicarboxylic acid g-lactone methyl ester. Grades: > 95%. CAS No. 95716-70-4. Molecular formula: C24H30O5. Mole weight: 398.50. | |
| Epobis | Epobis is a nonerythropoietic and neuroprotective agonist of the erythropoietin receptor with anti-Inflammatory and memory enhancing effects. Grades: 98%. | |
| Epothilone F | Epothilone F, an active metabolite of Epothilone D, prevents cancer cells from dividing by interfering with tubulin. Synonyms: (1S,3S,7S,10R,11S,12S,16R)-7,11-dihydroxy-3-[(E)-1-[2-(hydroxymethyl)-1,3-thiazol-4-yl]prop-1-en-2-yl]-8,8,10,12,16-pentamethyl-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione; epothilone F. Grades: >98%. CAS No. 208518-52-9. Molecular formula: C27H41NO7S. Mole weight: 523.69. | |
| Eprociclovir | Eprociclovir, an acyclovir analogue, has been found to have antiviral activity especially against herpes virus. Synonyms: A-5021; A5021; A 5021; AV-10; AV10; AV 10; Eprociclovir. UNII-227AL47VGS; AV-10; AC1LAAHS; 227AL47VGS; CHEMBL285442; SCHEMBL4550680; 2-amino-9-[[ (1S, 2R)-1, 2-bis (hydroxymethyl)cyclopropyl]methyl]-3H-purin-6-one. Grades: 98%. CAS No. 145512-85-2. Molecular formula: C11H15N5O3. Mole weight: 265.27. | |
| Eprodisate disodium | Eprodisate disodium is a sulfonated inhibitor of fibrillogenesis which coul be used in the treatment of amyloid A (AA) amyloidosis. Uses: Used in the treatment of amyloid a (aa) amyloidosis. Synonyms: disodium;propane-1,3-disulfonate. Grades: > 98 %. CAS No. 36589-58-9. Molecular formula: C3H6Na2O6S2. Mole weight: 248.19. | |
| Eprotirome | Eprotirome is a synthetic thyroid hormone mimetic as a thyroid hormone receptor beta agonists, lowers total and low-density lipoprotein cholesterol up to 40% without affecting high-density lipoprotein cholesterol levels and without deleterious side effects to the cardiovascular system. Uses: Thyroid hormone receptor beta agonists. Synonyms: KB-2115; KB 2115; KB2115; Eprotirome.3-[[3,5-dibromo-4-[4-hydroxy-3-(1-methylethyl)phenoxy]phenyl]amino-3-oxo-propanoic acid. Grades: ≥98%. CAS No. 355129-15-6. Molecular formula: C18H17Br2NO5. Mole weight: 487.14. | |
| EPZ020411 | EPZ020411, with potent anticancer activity, is an orally bioactive, selective inhibitor of PRMT6/8/1 with over 100-fold selective for other histone methyltransferases including four arginine methyltransferases (PRMT3, PRMT4, PRMT5, and PRMT7). Synonyms: N,N'-dimethyl-N'-[[5-[4-[3-[2-(oxan-4-yl)ethoxy]cyclobutyl]oxyphenyl]-1H-pyrazol-4-yl]methyl]ethane-1,2-diamineEPZ020411; EPZ 020411; EPZ-020411CHEMBL3589039GTPL9243SCHEMBL17 62195749LN, N'-Di methyl -N- ( {3- [4- ( {trans-3- [2- (Tetra hydro-2h-Pyran-4-yl ) ethoxy] cyclobutyl } oxy) pheny l. CAS No. 1700663-41-7. Molecular formula: C25H38N4O3. Mole weight: 442.59. | |
| EPZ020411 HCl | EPZ020411 hydrochloride is a potent and selective small molecule PRMT6 inhibitor with an IC50 of 10 nM, and it displays >10-fold and 20-fold selectivity over PRMT1/8. Synonyms: EPZ-020411 hydrochloride. Grades: ≥97%. CAS No. 2070015-25-5. Molecular formula: C25H39ClN4O3. Mole weight: 479.06. | |
| ER-000444793 | ER-000444793, a potent inhibitor of mitochondrial permeability transition pore (mPTP) opening, inhibits mPTP with an IC50 of 2.8?μM. R-000444793 neither affected cyclophilin D (CypD) enzymatic activity, nor displaced of CsA from CypD protein, suggesting a mechanism independent of CypD inhibition. Synonyms: N-(2-benzylphenyl)-2-oxo-1H-quinoline-4-carboxamide; ER-000444793; ER 000444793; ER000444793. CAS No. 792957-74-5. Molecular formula: C23H18N2O2. Mole weight: 354.4. | |
| Erastin2 | Erastin2 is a ferroptosis inducer and an inhibitor of the system xc- cystine/glutamate transporter, which inhibits glutamate release in CCF-STTG1 cells with an IC50 of 0.0035 μM. Synonyms: 2-[[4-[2-(4-chlorophenoxy)acetyl]-1-piperazinyl]methyl]-3-[4-(1-methylethoxy)[1,1'-biphenyl]-3-yl]-4(3H)-quinazolinone. Grades: ≥98%. CAS No. 1695533-44-8. Molecular formula: C36H35ClN4O4. Mole weight: 623.14. | |
| Erdafitinib | Erdafitinib, also known as JNJ-42756493, is a potent and selective orally bioavailable, pan fibroblast growth factor receptor (FGFR) inhibitor with potential antineoplastic activity. Synonyms: JNJ-42756493; JNJ 42756493; JNJ42756493; Erdafitinib. Grades: 98%. CAS No. 1346242-81-6. Molecular formula: C25H30N6O2. Mole weight: 446.55. | |
| ERGi-USU | ERGi-USU is a high affinity Rio Kinase 2 (RIOK2) inhibitor (Kd = 200 nM) which displays >6-fold selectivity for RIOK2 over a panel of 456 kinases. Synonyms: 1-[2-(2-Thiazolyl)diazenyl]-2-naphthalenol; 1-(1,3-thiazol-2-yldiazenyl)naphthalen-2-ol. Grades: ≥99% by HPLC. CAS No. 1147-56-4. Molecular formula: C13H9N3OS. Mole weight: 255.3. | |
| Eriocitrin | Eriocitrin is a powerful antioxidative flavonoid in lemon with lipid-lowering effects in a rat model of high-fat diet. It might play an important role in the control of the change in glutathione redox status in rat liver during exercise. These findings showed that Eriocitrin was effective in the prevention of oxidative damages caused by acute exercise-induced oxidative stress. Eriocitrin was suggested to be metabolized by intestinal bacteria, and then eriodictyol and 3,4-dihydroxyhydrocinnamic of its metabolite were absorbed. Following administration of Eriocitrin, plasma exhibited an elevated resistance effect to lipid peroxidation. Eriocitrin metabolites functioning as antioxidant agents are discussed. Uses: Antioxidant. Synonyms: (S)-3',4',5,7-TETRAHYDROXYFLAVANONE-7-[6-O-(ALPHA-L-RHAMNOPYRANOSYL)-BETA-D-GLUCOPYRANOSIDE]; ERIOCITRIN; ERIODICTYL-7-RUTINOSIDE; ERIODICTYOL-7-O-RUTINOSIDE; ERIODICTYOL-7-RUTINOSIDE; (S)-7-[[6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-5-hydroxy-4H-benzopyran-4-one; (s)-3',4',5,7-tetrahydroxyflavanone-7-[6-o-(α-l-rhamnopyranosyl)-β-d-glucopyranoside]; (2S)-2-(3,4-dihydroxyphenyl)-5-hydroxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxymethyl]oxan-2-yl]oxy-chroman-4-one. Grades: >98%. CAS No. 13463-28-0. Molecular formula: C27H32O15. Mole weight: 596.53. | |
| Erlosiban | Erlosiban, an iminopyrrolidin derivative, has been found to be a nonpeptide oxytocin receptor antagonist that could probably be used in the treatment of female infertility and preterm labour. It is still under Phase II clinical trail in Preterm labour. Synonyms: UOBE-001; OBE001; OBE001; NII-3765U8A1EC; CHEMBL1254025; 3765U8A1EC; Erlosiban; Erlosiban [INN]; [(2S,4Z)-2-(hydroxymethyl)-4-methoxyiminopyrrolidin-1-yl]-[4-(2-methylphenyl)phenyl]methanone. Grades: 98%. CAS No. 1477482-19-1. Molecular formula: C20H22N2O3. Mole weight: 338.41. | |
| Erlotinib Impurity 8 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: N-(3-Desethynylphenyl)-N-(3-bromophenyl) Erlotinib; N-(3-bromophenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine. Grades: > 95%. CAS No. 328528-74-1. Molecular formula: C20H22BrN3O4. Mole weight: 448.32. | |
| Erlotinib O-Desmethyl Metabolite Isomer (M14) HCl | OSI-420 (CP-473420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for the inhibition of human EGFR and EGFR autophosphorylation in tumor cells. Uses: For research used only. Synonyms: OSI420; OSI-420; OSI 420; CP473420; CP-473420; CP 473420; Desmethyl Erlotinib. Grades: > 95%. CAS No. 183320-51-6. Molecular formula: C21H22ClN3O4. Mole weight: 415.874. | |
| Erythronolide B | Cas No. 3225-82-9. | |
| Erythropoietin | Produced by the kidneys,this glycoprotein is involved in red blood cell production. It has a predicted molecular mass of ~21 kDa but migrates at ~37 kDa on SDS-PAGE. Synonyms: Betapoietin; Ep; EPO; Epocim; Epocrin; Epoetin; Epogis S; Epolyrec; Eposim; Erythropoietins; Erytrostim; Heberitro; Hematopoietin; Hemax; Hemopoietin; Hempoietine; Neuro-EPO; PDpoetin; Repotin; YiBei. CAS No. 11096-26-7. Molecular formula: C134H226N38O41. Mole weight: 3025.49000. | |
| Escibenzoline | It's an anti-arrhythmic drug. Synonyms: (-)-2-[(1S)-2,2-diphenylcyclopropyl]-4,5-dihydro-1H-imidazole; S-cibenzoline; Cibenzoline, (S)-; (-)-(S)-Cibenzoline; 1H-Imidazole, 2-(2,2-diphenylcyclopropyl)-4,5-dihydro-, (S)-; (S)-2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1H-imidazole. CAS No. 103419-18-7. Molecular formula: C18H18N2. Mole weight: 262.35. | |
| ESI 05 | ESI-05 is an Epac2 inhibitor that inhibits cAMP binding to EPAC2 and cAMP mediated EPAC2 guanine nucleotide exchange factor (GEF) activity (IC50 = 0.4 μM). It is selective for Epac2 over Epac1 and PKA at 25 μM. Synonyms: NSC 116966; 1,3,5-Trimethyl-2-[(4-methylphenyl)sulfonyl]benzene. Grades: ≥98% by HPLC. CAS No. 5184-64-5. Molecular formula: C16H18O2S. Mole weight: 274.38. | |
| ESI-09 | ESI-09 is a specific exchange protein directly activated by cAMP (EPAC) inhibitor with IC50 of 3.2 μM and 1.4 μM for EPAC1 and EPAC2, respectively, >100-fold selectivity over PKA.ESI-09 is a novel noncyclic nucleotide EPAC antagonist that is capable of specifically blocking intracellular EPAC-mediated Rap1 activation and Akt phosphorylation, as well as EPAC-mediated insulin secretion in pancreatic β cells. EPAC1 plays an important role in pancreatic cancer cell migration and invasion, and thus represents a potential target for developing novel therapeutic strategies for pancreatic cancer. Synonyms: ESI09; ESI 09; ESI-09. Grades: >98%. CAS No. 263707-16-0. Molecular formula: C16H15ClN4O2. Mole weight: 330.77. | |
| Esmolol Dimer | Esmolol Dimer is an impurity of Esmolol. Esmolol is a cardioselective β-blocker which has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic or membrane stabilizing activities at recommended therapeutic doses. Synonyms: 4-[2-hydroxy-3-[[3-[4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]-1-oxopropyl](1-methylethyl)amino]propoxy]-benzenepropanoic Acid Methyl Ester. Grades: > 95%. CAS No. 98903-89-0. Molecular formula: C31H46N2O7. Mole weight: 558.7. | |
| Esmolol Impurity 1 | Esmolol Impurity 1 is an impurity of Esmolol. Esmolol is a cardioselective β-blocker which has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic or membrane stabilizing activities at recommended therapeutic doses. Synonyms: Methyl 3[4-(2,3-Epoxypropoxy)phenyl]propionate; 3-(4-(2,3-Epoxypropoxy)phenyl)propionic Acid Methyl Ester. Grades: >95%. CAS No. 81147-94-6. Molecular formula: C13H16O4. Mole weight: 236.26. | |
| Esomeprazole Impurity 22 | Esomeprazole Impurity 22 is an impurity of Esomeprazole. Esomeprazole is the (S)-(-)-enantiomer of omeprazole, a medication of the proton pump inhibitor class used for the treatment of gastroesophageal reflux disease (GERD) and gastric ulcer. Synonyms: 2-Pyridinemethanol, 4-hydroxy-3,5-dimethyl- (9CI). Grades: ≥95%. CAS No. 727375-13-5. Molecular formula: C8H11NO2. Mole weight: 153.18. | |
| Esomeprazole Impurity H215/02 | Esomeprazole Impurity H215/02 is an impurity of Esomeprazole. Esomeprazole is the (S)-(-)-enantiomer of omeprazole, a medication of the proton pump inhibitor class used for the treatment of gastroesophageal reflux disease (GERD) and gastric ulcer. Synonyms: 2,2'-(disulfanediylbis(methylene))bis(1-(5-methoxy-1H-benzo[d]imidazol-2-yl)-3,5-dimethylpyridin-4(1H)-one). Grades: ≥95%. CAS No. 1803449-02-6. Molecular formula: C32H32N6O4S2. Mole weight: 628.76. | |
| Esomeprazole Impurity K | An impurity of Esomeprazole. Esomeprazole is the (S)-(-)-enantiomer of omeprazole, a medication of the proton pump inhibitor class used for the treatment of gastroesophageal reflux disease (GERD) and gastric ulcer. Synonyms: Omeprazole Impurity K (H215/01); Sodium-2-(((3,5-dimethyl-4-oxo-1,4-dihydropyridin-2-yl)methyl)sulfinyl)-5-oxidobenzo[d]imidazol-1-ide. Grades: ≥95%. Molecular formula: C15H13N3Na2O3S. Mole weight: 361.33. | |
| Esomeprazole magnesium salt | The magnesium salt form of Esomeprazole which is a proton pump inhibitor so that could be probably useful in the treatment of sorts of digestive tract diseases through decreasing acid secretion. It was just Launched for Heartburn in USA. Uses: The magnesium salt form of esomeprazole which is a proton pump inhibitor so that could be probably useful in the treatment of sorts of digestive tract diseases through decreasing acid secretion. Synonyms: Esomeprazole (magnesium salt). Grades: 98%. CAS No. 1198768-91-0. Molecular formula: C17H18MgN3O3S. Mole weight: 368.71. | |
| Esomeprazole magnesium trihydrate | Esomeprazole magnesium trihydrate acts as a gastric proton pump inhibitor (PPI). In adults, esomeprazole is indicated for the treatment and maintenance of healing of erosive esophagitis, relieving of GERD symptoms; reduction of the risk for NSAID-associated gastric acid production. Synonyms: Esomeprazole (Magnesium trihydrate); (S)-omeprazole magnesium trihydrate; Nexium; KS-1054; KS 1054; KS1054. Grades: ≥ 98%. CAS No. 217087-09-7. Molecular formula: C34H42MgN6O9S2. Mole weight: 767.17. | |
| Esomeprazole potassium | Esomeprazole potassium is a proton pump inhibitor which acts as selective inhibiton of H+/K+-ATPase. With antiulcerative effects in vivo, it treats or ameliorates peptic ulcer or irritation of the gastrointestinal tract. Uses: Anti-ulcer agents. Synonyms: potassium;5-methoxy-2-[(S)-(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]benzimidazol-1-ide AstraZeneca Brand of Esomeprazole Magnesium Esomeprazole Esomeprazole Magnesium Esomeprazole Potassium Esomeprazole Sodium Esomeprazole Strontium Esomeprazole. CAS No. 161796-84-5. Molecular formula: C17H18KN3O3S. Mole weight: 383.51. | |
| Estra-1,3,5(10)-triene-3,17-diol,7-(9-bromononyl)-,17-acetate,(7a,17b)- | Estra-1,3,5(10)-triene-3,17-diol,7-(9-bromononyl)-,17-acetate,(7a,17b)- (CAS# 875573-66-3 ) is a useful research chemical. Synonyms: (7a,17b)-7-(9-bromononyl)-estra-1,3,5(10)-triene-3,17-diol 17-acetate. Grades: 95 %. CAS No. 875573-66-3. Molecular formula: C29H43BrO3. Mole weight: 519.55. | |
| Estradiol 3-sulfamate | Estradiol 3-sulfamate, also known as J 995 or BLE 00084, is a potent, long-acting, and orally active steroid sulfatase inhibitor (IC50= 251 nM, and Ki= 133 nM for estrone sulfatase) to reach Phase ? clinical research for the treatment of endometriosis. Synonyms: [(8R,9S,13S,14S,17S)-17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] sulfamate; E2MATE cpd; estradiol-3-O-sulfamate. CAS No. 172377-52-5. Molecular formula: C18H25NO4S. Mole weight: 351.46. | |
| Estramustine | Estramustine, a derivative of estradiol, is an alkylating antineoplastic agent that is used in the treatment of prostate cancer throughout the world. Uses: Used treatment of breast cancer. also used in the treatment of prostate cancer. Synonyms: Estramustine; NSC 89201; NSC-89201; NSC89201; LEO 275; LEO-275; LEO275; RO 21-8837; [(8R,9S,13S,14S,17S)-17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] N,N-bis(2-chloroethyl)carbamate. Grades: ≥98%. CAS No. 2998-57-4. Molecular formula: C23H31Cl2NO3. Mole weight: 440.4. | |
| Estriol | Estriol is a metabolite of 17β-estradiol with much lower biological activity. It is the primary estrogen found in the urine. Large quantities of estriol and estrone are produced by the placenta during pregnancy. These are also the primary estrogens produced by adipose tissue in men and in post-menopausal women. Synonyms: 16α-hydroxy-17β-estradiol; 1,3,5(10)-Estratriene-3,16α, 17β-triol; E3; Oestriol; Ovestin; Estratriol; Ovestrion. Grades: 0.98. CAS No. 50-27-1. Molecular formula: C18H24O3. Mole weight: 288.387. | |
| Estromustine | Estromustine is a metabolite of estramustine phosphate, an antineoplastic agent used for the treatment of prostate cancer. CAS No. 62899-40-5. Molecular formula: C23H29Cl2NO3. Mole weight: 438.39. | |
| Etazolate hydrochloride | Etazolate hydrochloride is a phosphodiesterase inhibitor with selectivity for PDE4 (IC50 = 2.0 μM). Synonyms: 1-Ethyl-4-[(1-methylethylidene)hydrazino]-1H-pyrazolo-[3,4-b]-pyridine-5-carboxylic acid, ethyl ester hydrochloride; Etazolate HCl. Grades: ≥98% by HPLC. CAS No. 35838-58-5. Molecular formula: C14H19N5O2.HCl. Mole weight: 325.8. | |
| ETC-206 | ETC-206 is a selective MNK1 and MNK2 inhibitor with IC50 of 64 nM and 86 nM, respectively. Synonyms: ETC206; ETC 206. Grades: 98%. CAS No. 1464151-33-4. Molecular formula: C25H20N4O2. Mole weight: 408.5. | |
| Etebenecid | Etebenecid, a benzenesulfonic acid derivative, could be used to reduce uric acid levels acting as a uricosuric agent. Uses: Etebenecid could be used to reduce uric acid levels acting as a uricosuric agent. Synonyms: Etebenecidum; Etebenecid; NSC 49467; NSC-49467; NSC49467 Ethebenecide; Urelim; N,N-DIETHYL-4-SULFAMOYLBENZOIC ACID; 4-((diethylamino)sulfonyl)-benzoicaci; p-(diethylsulfamoyl)-benzoicaci; p-(diethylsulfamoyl)benzoicacid; Antidipsin; Etebenecid. Grades: 95%. CAS No. 1213-06-5. Molecular formula: C11H15NO4S. Mole weight: 257.31. | |
| Ethanol, 2-(2-ethoxyphenoxy)-, methanesulfonate | One of the impurities of Tamsulosin, which is an α1-adrenoceptor antagonist and could be used against benign prostatic hypertrophy. Synonyms: 2-(2-ethyloxyphenoxy)ethyl methanesulfonate. CAS No. 169506-15-4. Molecular formula: C11H16O5S. Mole weight: 260.31. | |
| Ethoxychelerythrine | Cas No. 79559-55-0. | |
| Ethyl 1-[4-(acetylamino)benzyl]-4-(2-phenylethyl)piperidine-4-carboxylate | ML-335 is an agonist of μ-opioid receptor (OPRM1)-occupancy of δ-opioid receptors (OPRD1) heterodimerization. Synonyms: ML 335; ML335; CID-23723457; CYM 51010; Ethyl 1-[4-(acetylamino)benzyl]-4-(2-phenylethyl)piperidine-4-carboxylate. Grades: ≥98%. CAS No. 1069498-96-9. Molecular formula: C25H32N2O3. Mole weight: 408.5. | |
| Ethyl 1-(4-methoxyphenyl)-7a-morpholino-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-3a,4,5,6,7,7a-hexahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate | An impurity of Apixaban, a direct factor Xa inhibitor used as an anticoagulant for the prevention of venous thromboembolism and stroke in atrial fibrillation. CAS No. 1619934-76-7. Molecular formula: C31H37N5O6. Mole weight: 575.7. | |
| Ethyl 2,3,4,6-tetra-O-acetyl-a-D-thioglucopyranoside | Ethyl 2,3,4,6-tetra-O-acetyl-α-D-thioglucopyranoside, a complex and intriguing biomedical compound with vast potential, is widely employed in the pharmaceutical industry. It assumes a pivotal role as an invaluable intermediate in the intricate process of synthesizing potential drugs, targeting an array of debilitating diseases. Synonyms: Ethyl 2,3,4,6-tetra-O-acetyl-a-D-thioglucopyranoside; 52645-73-5; [(2R,3R,4S,5R,6R)-3,4,5-triacetyloxy-6-ethylsulfanyloxan-2-yl]methyl acetate; (2R,3R,4S,5R,6R)-2-(Acetoxymethyl)-6-(ethylthio)tetrahydro-2H-pyran-3,4,5-triyl triacetate; Ethyl 2,3,4,6-tetra-O-acetyl-alpha-D-thioglucopyranoside; Ethyl 2,3,4,6-tetra-O-acetyl-b-D-thioglucopyranoside; MFCD00797608; AKOS015909744; BS-17249; F17517; W-202715; Ethyl 1-thio-B-D-glucopyranoside 2,3,4,6-tetraacetate; Ethyl 2,3,4,6-Tetra-O-acetyl-ss-D-thioglucopyranoside; Ethyl 2,3,4,6-tetra-O-acetyl-1-thio--D-glucopyranoside; Ethyl 2,3,4,6-Tetra-O-acetyl-beta-D-thioglucopyranoside; B-D-GLUCOPYRANOSIDE, ETHYL 1-THIO-, 2,3,4,6-TETRAACETATE. CAS No. 41670-79-5. Molecular formula: C16H24O9S. Mole weight: 392.42. | |
| Ethyl 2,3,4,6-tetra-O-acetyl-b-D-thioglucopyranoside | Ethyl 2,3,4,6-tetra-O-acetyl-b-D-thioglucopyranoside, known as ETATG, reigns as a prized gem within the realm of biomedical exploration. In the quest for innovative pharmacological breakthroughs, it assumes the role of a sentinel, shielding delicate compounds. Its indomitable presence enables the construction of a myriad of pharmaceutical elixirs, meticulously tailored to combat a pantheon of maladies. Stretching beyond the confines of its initial form, ETATG metamorphoses into a catalyst for therapeutic prospects, spanning the domains of oncology, diabetology, and neurodegeneration. CAS No. 52645-73-5. Molecular formula: C16H24O9S. Mole weight: 392.5. | |
| Ethyl 2,4-dihydroxy-6-pentylbenzoate | Ethyl 2,4-dihydroxy-6-pentylbenzoate, a component recognized for its potential in tackling oxidative stress-related illnesses, cancer, and inflammation, stands out for its anti-inflammatory, anti-tumor, and antioxidant capabilities. Pharmaceutical prospects are keen to explore its therapeutic potential, given its unique properties. Synonyms: Ethyl Olivetolate; 2,4-Dihydroxy-6-pentyl-benzoic acid ethyl ester; Benzoic acid, 2,4-dihydroxy-6-pentyl-, ethyl ester. Grades: ≥95%. CAS No. 38862-65-6. Molecular formula: C14H20O4. Mole weight: 252.31. | |
| Ethyl 2-[5-(4-methylpiperazinyl)benzimidazol-2-yl]acetate | An impurity of Dovitinib, a potent VEGFR inhibitor exhibiting antitumor activity. Synonyms: ethyl 2-(5-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)acetate. CAS No. 402948-37-2. Molecular formula: C16H22N4O2. Mole weight: 302.37. | |
| Ethyl 2-bromothiophene-3-carboxylate | Ethyl 2-bromothiophene-3-carboxylate, a significant interstitial compound, is extensively utilized in the composition of drugs and pesticides. Its role as a fundamental precursor for anticancer, anti-inflammatory, and antifungal agents cannot be overstated. Furthermore, it is involved in the creation of state-of-the-art herbicides and insecticides, given its pivotal role in their synthesis. Synonyms: 2-Bromo-3-thiophenecarboxylic acid ethyl ester. CAS No. 632325-50-9. Molecular formula: C7H7BrO2S. Mole weight: 235.1. | |
| Ethyl(2-methylpropyl)amine hydrochloride | Ethyl(2-methylpropyl)amine hydrochloride, a pharmaceutical intermediate, is a white crystalline powder with versatile applications in the synthesis of organic compounds. It serves as an essential building block in the production of amides and esters, consequently contributing to the development of drugs for debilitating conditions like Alzheimer's and Parkinson's disease. Its proficiency in aiding therapeutic breakthroughs and enabling the advancement of the medical industry underscores its significance. Synonyms: N-Ethyl-N-isobutylamine hydrochloride; Ethylisobutylamine hydrochloride; N-Ethyl-2-methyl-1-propanamine hydrochloride (1:1); 1-Propanamine, N-ethyl-2-methyl-, hydrochloride (1:1). Grades: ≥95%. CAS No. 63528-29-0. Molecular formula: C6H16ClN. Mole weight: 137.65. | |
| Ethyl 3-(acetoxy)crotonate | Ethyl 3-(acetoxy)crotonate is an impurity of Edaravone, which is a medication used to treat stroke and amyotrophic lateral sclerosis (ALS). Synonyms: 2-Butenoic acid, 3-(acetyloxy)-, ethyl ester; Crotonic acid, 3-hydroxy-, ethyl ester, acetate; Crotonic acid, β-hydroxy-, ethyl ester, acetate; Ethyl 3-(acetyloxy)-2-butenoate; Ethyl 3-acetoxy-2-butenoate; Ethyl 3-acetoxycrotonate; Ethyl acetoacetate enol acetate; Ethyl β-acetoxycrotonate; NSC 167587. Grades: ≥95%. CAS No. 29214-62-8. Molecular formula: C8H12O4. Mole weight: 172.18. | |
| Ethyl 3-o-benzyl-4,6-o-benzylidene-2-deoxy-2-phthalimido-beta-d-thioglucopyranoside | Ethyl 3-o-benzyl-4,6-o-benzylidene-2-deoxy-2-phthalimido-beta-d-thioglucopyranoside is an immensely significant biomedical compound, used for studying ailments like cancer, diabetes and inflammation. Synonyms: Ethyl 3-o-benzyl-4,6-o-benzylidene-2-deoxy-2-phthalimido-beta-d-thioglucopyranoside; 2-((4aR,6S,7R,8R,8aS)-8-(Benzyloxy)-6-(ethylthio)-2-phenylhexahydropyrano[3,2-d][1,3]dioxin-7-yl)isoindoline-1,3-dione; 2-[(4Ar,6S,7R,8R,8aS)-6-ethylsulfanyl-2-phenyl-8-phenylmethoxy-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-7-yl]isoindole-1,3-dione; MFCD15144993; Ethyl3-o-benzyl-4,6-o-benzylidene-2-deoxy-2-phthalimido-beta-d-thioglucopyranoside. CAS No. 129519-27-3. Molecular formula: C30H29NO6S. Mole weight: 531.6. | |
| Ethyl 4-(2-methoxypropan-2-yl)-2-propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-5-carboxylate | An impurity of Olmesartan, which is a specific angiotensin II type 1 (AT1) receptor antagonist with antihypertensive effect. CAS No. 1039762-39-4. Molecular formula: C46H46N6O3. Mole weight: 730.9. | |
| Ethyl 4,6-O-Benzylidene-3-O-(2-methylnaphthyl)-2-O-benzoyl-1-thio-β-D-glucopyranoside | Ethyl 4,6-O-Benzylidene-3-O-(2-methylnaphthyl)-2-O-benzoyl-1-thio-β-D-glucopyranoside, a remarkable compound enhancing the biomedical industry, unveils promising therapeutic properties for diverse ailments. Its immense potential in precise drug targeting and disease intervention has captivated researchers. Grades: 98%. CAS No. 352008-11-8. Molecular formula: C33H32O6S. Mole weight: 556.679. | |
| Ethyl 4-amino-2-phenyl-1H-imidazole-5-carboxylate | Ethyl 4-amino-2-phenyl-1H-imidazole-5-carboxylate is a useful research chemical. Synonyms: Ethyl-5-amino-2-phenylimidazole-4-carboxylate. Grades: 95 %. CAS No. 32704-59-9. Molecular formula: C12H13N3O2. Mole weight: 231.25. | |
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