BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| BFCAs-1 | BFCAs-1 is a polyamino polycarboxylic bifunctional chelating agent, which has a broad range of applications in chemistry, biology and medicine and diagnostic imaging. Grades: >98%. CAS No. 585531-74-4. Molecular formula: C32H60N4O8. Mole weight: 628.84. |  |
| BFF 122 | BFF 122 is a potent and selective inhibitor of kynurenine aminotransferase II (IC50 = 1 μM and >30 μM for KAT II and KAT I respectively). Synonyms: BFF122; BFF 122; BFF-122; BF5; (S)-9-(4-Amino-piperazin-1-yl)-8-fluoro-3-methyl-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid. Grades: 99%. CAS No. 1152314-49-2. Molecular formula: C17H19FN4O4. Mole weight: 362.36. | |
| BGJ-398 | BGJ398, also known as NVP-BGJ398, is a pan FGFR kinase inhibitor, and is an orally bioavailable pan inhibitor of human fibroblast growth factor receptors (FGFRs) with potential antiangiogenic and antineoplastic activities. BGJ398 selectively binds to and inhibits the activities of FGFRs, which may result in the inhibition of tumor angiogenesis and tumor cell proliferation, and the induction of tumor cell death. Synonyms: 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea; NVPBGJ398; NVPBGJ 398; NVPBGJ-398; BGJ398; BGJ-398; BG J398; Infigratinib. Grades: 0.98. CAS No. 872511-34-7. Molecular formula: C26H31Cl2N7O3. Mole weight: 560.48. | |
| BI 01383298 | BI01383298 is a potent and selective inhibitor of human SLC13A5 (Na+/citrate co-transporter) with IC50 of 56 nM in HEK cells overexpressing hSLC13A5. BI01383298 is highly selective over other family members and other transporters with >1000-fold selectivity over others. Synonyms: 1-[(3,5-Dichlorophenyl)sulfonyl]-N-[(4-fluorophenyl)methyl]-4-piperidinecarboxamide. Grades: ≥98%. CAS No. 2227549-00-8. Molecular formula: C19H19Cl2FN2O3S. Mole weight: 445.34. | |
| B I09 | B I09 is a cell permeable IRE-1 RNase inhibitor (IC50 = 1.23 μM) that blocks IRE-1/XBP1 pathway. B I09 exhibits an inhibitory effect on growth of human chronic lymphocytic leukemia (CLL) cells in vitro and promotes CLL regression in a mouse model. Uses: Potential treatment of cll. Synonyms: B-I09; B I09; BI09; 7-(1,3-Dioxan-2-yl)-1,2,3,4-tetrahydro-8-hydroxy-5H-[1]benzopyrano[3,4-c]pyridin-5-one. Grades: ≥98% by HPLC. CAS No. 1607803-67-7. Molecular formula: C16H17NO5. Mole weight: 303.31. | |
| BI-2852 | BI-2852 is a KRAS inhibitor. It blocks the interaction of GEF, GAP and effectors with KRAS, thereby inhibiting downstream signal transduction and producing anti-proliferative effects in KRAS mutant cells. Synonyms: BI-2852; 2375482-51-0; CHEMBL4750445; (3~{S})-3-[2-[[[1-[(1-methylimidazol-4-yl)methyl]indol-6-yl]methylamino]methyl]-1~{H}-indol-3-yl]-5-oxidanyl-2,3-dihydroisoindol-1-one; (3S)-5-hydroxy-3-[2-[[[1-[(1-methylimidazol-4-yl)methyl]indol-6-yl]methylamino]methyl]-1H-indol-3-yl]-2,3-dihydroisoindol-1-one; F0K; SCHEMBL24414712; BCP31539; EX-A4793; BDBM50549225; s8959; AKOS040732592; BI2852; BI 2852; MS-29593; HY-126247; CS-0100975; A934943; (S)-5-Hydroxy-3-(2-((((1-((1-methyl-1H-imidazol-4-yl)methyl)-1H-indol-6-yl)methyl)amino)methyl)-1H-indol-3-yl)isoindolin-1-one; (S)-5-hydroxy-3-(2-(((1-((1-methyl-1H-imidazol-4-yl)methyl)-1H-indol-6-yl)methylamino)methyl)-1H-indol-3-yl)isoindolin-1-one. Grades: ≥98% by HPLC. CAS No. 2375482-51-0. Molecular formula: C31H28N6O2. Mole weight: 516.6. | |
| BI-3812 | BI-3812 is potent and efficacious BCL6 inhibitor. It inhibits the BTB domain of BCL6 with an IC50 of ≤3 nM. The high potency and good permeability properties of BI-3812 make this molecule a very good cellular probe compound for testing hypotheses around BCL6 biology. The transcription factor BCL6 is a known driver of oncogenesis in lymphoid malignancies, including diffuse large B cell lymphoma (DLBCL). Synonyms: BI-3812; 2166387-64-8; CHEMBL4755229; 1-(5-chloro-4-((8-methoxy-1-methyl-3-(2-(methylamino)-2-oxoethoxy)-2-oxo-1,2-dihydroquinolin-6-yl)amino)pyrimidin-2-yl)-N,N-dimethylpiperidine-4-carboxamide; SCHEMBL20284237; AMY16876; BCP31903; EX-A2841; BDBM50546197; s8735; AKOS040741329; SB40386; BI 3812; BI3812; AC-31571; MS-30157; HY-111381; CS-0040299; A935150; EN300-22885148; Z3417458909; 1-[5-chloro-4-({8-methoxy-1-methyl-3-[(methylcarbamoyl)methoxy]-2-oxo-1,2-dihydroquinolin-6-yl}amino)pyrimidin-2-yl]-N,N-dimethylpiperidine-4-carboxamide; 1-[5-Chloro-4-({8-methoxy-1-methyl-3-[2-(methylamino)-2-oxoethoxy]-2-oxo-1,2-dihydro-6-quinolinyl}amino)-2-pyrimidinyl]-N,N-dimethyl-4-piperidinecarboxamide; 1-[5-chloro-4-[[8-methoxy-1-methyl-3-[2-(methylamino)-2-oxoethoxy]-2-oxoquinolin-6-yl]amino]pyrimidin-2-yl]-N,N-dimethylpiperidine-4-carboxamide. Grades: ≥98%. CAS No. 2166387-64-8. Molecular formula: C26H32ClN7O5. Mole weight: 558.03. | |
| BI-44847 | BI-44847 is a synthetic bio-active chemical had been in phase II clinical trials for the treatment of type 2 diabetes. Uses: Sodium-glucose transporter 2 inhibitors. Synonyms: BI-44847; BI 44847; BI44847; UNII-43WJ33399D; beta-D-Glucopyranoside,4-((2-fluoro-4-methoxyphenyl)methyl)- 5-methyl-1-(1-methylethyl)-1H-pyrazol-3-yl. Grades: ≥98%. CAS No. 421592-30-5. Molecular formula: C21H29FN2O7. Mole weight: 440.46. | |
| BI 6015 | BI 6015 is a hepatocyte nuclear factor 4α (HNF4α) antagonist that suppresses expression of known HNF4α target genes. BI 6015 produces cytotoxicity in a range of tumor cell lines, including human hepatocellular carcinoma. Synonyms: BI6015; BI 6015; BI-6015. 2-Methyl-1-[(2-methyl-5-nitrophenyl)sulfonyl]-1H-benzimidazole. Grades: ≥98% by HPLC. CAS No. 93987-29-2. Molecular formula: C15H13N3O4S. Mole weight: 331.35. | |
| BI-6C9 | BI-6C9 ( N-[4-[(4-Aminophenyl)thio]phenyl]-4-[[(4-methoxyphenyl)sulfonyl]amino]-Butanamide) is a tBid inhibitor that possesses antiapoptotic properties. Bid plays an essential role in matrine-induced AIF translocation. BI-6C9 also blocked matrine-induced AIF translocation detected by confocal microscopy. Bid inhibitor BI-6C9 was applied to confirm the essential role of Bid in cell death induced by matrine. Synonyms: N-[4-[(4-aminophenyl)thio]phenyl]-4-[[(4-methoxyphenyl)sulfonyl]amino]-butanamide. Grades: ≥98%. CAS No. 791835-21-7. Molecular formula: C23H25N3O4S2. Mole weight: 471.6. | |
| BI 9321 | BI 9321 is a nuclear receptor-binding SET domain (NSD) 3 antagonist with IC50 of 1.2 μM. It is also selectively binds the PWWP1 domain of NSD3 with Kd of 166 nM. BI 9321 antagonizes the interaction of H3 with NSD3-PWWP1 in U2OS cells. High selectivity of BI-9321 was confirmed using in vitro assays and quantitative chemical proteomics. Cellular target engagement was confirmed with FRAP (Fluorescence Recovery After Photobleaching) and BRET (Bioluminescence Resonance Energy Transfer) at 1 μM. Synonyms: (4-(5-(7-Fluoroquinolin-4-yl)-1-methyl-1H-imidazol-4-yl)-3,5-dimethylphenyl)methanamine trihydrochloride. Grades: ≥98%. Molecular formula: C22H21FN4ยท3HCl. Mole weight: 469.81. | |
| Bialamicol hydrochloride | Bialomicol is a synthetic bio-active chemical. Uses: A synthetic bio-active chemical. Synonyms: Bialamicol Hydrochloride; Bialamicol hydrochloride [USAN]; CAM 807; CAM-807; Camoform hydrochloride; CI 301; CI301; CI-301; NSC 6386;PAA 701 dihydrochloride; PAA-701; PAA701 dihydrochloride; SN 6771 dihydrochloride; UNII-VIQ3X36S8C;2-(diethylaminomethyl)-4-[3-(diethylaminomethyl)-4-hydroxy-5-prop-2-enylphenyl]-6-prop-2-enylphenol;dihydrochloride. Grades: ≥98%. CAS No. 3624-96-2. Molecular formula: C28H42Cl2N2O2. Mole weight: 509.556. | |
| BIBB 515 | 2,3-Oxidosqualene cyclase (OSC) is an important enzyme in the biosynthesis of animal, plant, and fungal sterols. BIBB 515 is a selective and potent inhibitor of 2,3-oxidosqualene cyclase (OSC) with an ED50 value of 0.2-0.5 and 0.36-33.3 mg/kg in rats and mice, respectively. It is concluded that the lipid-lowering effect of BIBB 515 is mainly the result of an inhibition of LDL production rather than due to an increase in LDL catabolism. OSC inhibitors may offer a novel approach for lipid-lowering therapy. Synonyms: BIBB-515; BIBB515. Grades: ≥98%. CAS No. 156635-05-1. Molecular formula: C22H21ClN2O2. Mole weight: 380.9. | |
| BIBR 1532 | BIBR 1532 is a potent, selective, non-competitive telomerase inhibitor with IC50 of 100 nM.BIBR1132 is highly selective for inhibition of telomerase, resulting in delayed growth arrest of tumor cells. Treatment of cancer cells with BIBR1532 leads to progressive telomere shortening, consecutive telomere dysfunction, and finally growth arrest after a lag period that is largely dependent on initial telomere length. Synonyms: BIBR1532; BIBR-1532; BIBR 1532. Grades: >98%. CAS No. 321674-73-1. Molecular formula: C21H17NO3. Mole weight: 331.36. | |
| Bicifadine hydrochloride | Bicifadine hydrochloride is a potent antagonist of SLC6A2 (noradrenalin transporter) (IC50 = 55 nM). Bicifadine also has antagonistic activity at the 5-HT receptors and dopamine transporters (IC50 = 117 nM and 910 nM, respectively). It exhibits antinociceptive and antiallodynic properties in rodent models of acute, persistent, and chronic pain. Uses: The treatment of acute and chronic pain. Synonyms: 1-(4-Methylphenyl)-3-azabicyclo[3.1.0]hexane hydrochloride. Grades: ≥98% by HPLC. CAS No. 66504-75-4. Molecular formula: C12H15N.HCl. Mole weight: 209.72. | |
| BigLEN (mouse) | BigLEN (mouse) is a proSAAS-derived neuropeptide that acts as a GPR171 agonist. It regulates food intake in mice, and suppresses the release of glutamate onto parvocellular neurons of the paraventricular nucleus in a process dependent upon activation of postsynaptic G proteins. CAS No. 501036-69-7. Molecular formula: C78H130N24O22. Mole weight: 1756.03. | |
| BigLEN (rat) | BigLEN (rat) is a proSAAS-derived peptide that acts as a potent GPR171 agonist (EC50 = 1.6 nM). It regulates body weight in mice and promotes the outgrowth of neurites in Neuro2A cells. CAS No. 369377-66-2. Molecular formula: C76H128N24O23. Mole weight: 1746. | |
| BI-Lawsone | BI-Lawsone is a natutral compound isolated from Lomatia ferruginea. Lawsone is a red-orange dye. Synonyms: Bilawsone; 3,3'-Bilawsone; 2,2'-Bis(3-hydroxy-1,4-naphthoquinone); 4-hydroxy-3-(1-hydroxy-3,4-dioxonaphthalen-2-yl)naphthalene-1,2-dione. CAS No. 33440-64-1. Molecular formula: C20H10O6. Mole weight: 346.3. | |
| BIM 23042 | Cas No. 111857-96-6. | |
| BIM5078 | Hepatocyte nuclear factor (HNF)4α is a key regulator of gene expression in cell types playing an important role in metabolic homeostasis, such as hepatocytes, enterocytes, as well as pancreatic β cells. BIM5078 is a potent hepatocyte nuclear factor 4a (HNF4a) antagonist that directly binds to ligand-binding pocket of HNF4α with an EC50 value of 11.9 nM and modulates the expression of known HNF4a target genes. The EC50 of BIM5078 was calculated to be 11.9 nM and further analyses of the data using the Hill equation showed that the Hill coefficient for BIM5078 was 0.9, consistent with a single binding complex between BIM5078 and HNF4&alpha. Grades: ≥98%. CAS No. 337506-43-1. Molecular formula: C14H10ClN3O4S. Mole weight: 351.8. | |
| Bimatoprost Acid | Bimatoprost Acid is an impurity of the antiglaucoma agent Bimatoprost. It is a metabolically stable analog of PGF2α and is a potent agonist for the FP receptor. Synonyms: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-5-heptenoic Acid; 17-Phenyl-18,19,20-trinor-PGF2α; PhXA 70; (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-pentenyl]cyclopentyl]-5-heptenoic Aci. Grades: > 95%. CAS No. 38344-08-0. Molecular formula: C23H32O5. Mole weight: 388.51. | |
| Bimatoprost Acid Methyl Ester | Bimatoprost Acid Methyl Ester is an impurity of the antiglaucoma agent Bimatoprost. Synonyms: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-5-heptenoic Acid Methyl Ester; 17-Phenyl-18,19,20-trinor-PGF2α Methyl Ester. Grades: > 95%. CAS No. 38315-47-8. Molecular formula: C24H34O5. Mole weight: 402.54. | |
| BINAP, mono-oxide | BINAP, mono-oxide (CAS# 204862-91-9 ) is a useful research chemical. Grades: 95 %. CAS No. 204862-91-9. Molecular formula: C44H32OP2. Mole weight: 638.69. | |
| Bindarit | Bindarit treatment inhibits the release of MCP-1 from IL-1 stimulated osteoblast cell line Saos-2. Synonyms: Bindarit; AF-2838; AF2838; AF 2838. Grades: >98%. CAS No. 130641-38-2. Molecular formula: C19H20N2O3. Mole weight: 324.37. | |
| Binfloxacin | Binfloxacin, a bio-active chemical compound, has antibiotic effect. Uses: Binfloxacin has antibiotic effect. Synonyms: 3-Quinolinecarboxylicacid, 7-(1,4-diazabicyclo[3.2.2]non-4-yl)-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-;7-(1,4-Diazabicyclo[3.2.2]non-4-yl)-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid;CP73049;CP-73049. Grades: 95%. CAS No. 108437-28-1. Molecular formula: C19H22FN3O3. Mole weight: 359.39. | |
| BIO | BIO is a potent and reversible inhibitor of GSK-3 with IC50 of 5 nM for GSK-3α/&beta. BIO enhances reprogramming of mouse fibroblasts, neural stem cells, and thymocytes to induced pluripotent stem (iPS) cells. It also promotes differentiation of cardiomyocytes from human ES and iPS cells. Synonyms: GSK-3 Inhibitor IX; 6-bromoindirubin-3-oxime; 6-bromo-3-(3-nitroso-1H-indol-2-yl)-1H-indol-2-ol. Grades: >98%. CAS No. 667463-62-9. Molecular formula: C16H10BrN3O2. Mole weight: 356.17. | |
| BIO 1211 | BIO 1211 is a selective and high affinity integrin α4β1 (Very Late Antigen 4; VLA-4) inhibitor with 200-fold selectivity for the activated form of α4β1 (KD = 70 pM; IC50=0.004 μM). Synonyms: BIO-1211; BIO1211. Grades: >98%. CAS No. 187735-94-0. Molecular formula: C36H48N6O9. Mole weight: 708.8. | |
| BIO 5192 | BIO 5192 is a selective and potent inhibitor of integrin α4β1 (Very Late Antigen-4; VLA-4) (Kd < 10 pM) with selectivity for α4β1 over a range of other integrins (IC50 values are 1.8, 138, 1053,> 500 and > 10,000 nM for α4β1, α9β1, α2β1, α4β7 and αIIbβ3, respectively). BIO 5192 causes a 30-fold increase in mobilization of murine hematopoietic stem and progenitors (HSPCs) over basal levels. Synonyms: BIO-5192; AMD-15057; BIO 5192; AMD 15057; BIO5192; AMD15057; (2S) -2- [ [ [ (2S) -1- [ (3, 5-Dichlorophenyl) sulfonyl] -2-pyrrolidinyl] carbonyl] amino] -4- [ [ (2S) -4-methyl-2- [methyl [2- [4- [ [ [ (2-methylphenyl) amino] carbonyl] amino] phenyl] acetyl] amino] -1-oxopentyl] amino] butanoic acid. Grades: ≥98% by HPLC. CAS No. 327613-57-0. Molecular formula: C38H46Cl2N6O8S. Mole weight: 817.78. | |
| Biotiin-Amylin, human amidated | Grades: ≥95%. CAS No. 1678415-18-3. Molecular formula: C175H275N53O57S3. Mole weight: 4129.56. | |
| (+)-Biotin azidopropylamide | (+)-Biotin azidopropylamide, a scientific compound, is a highly effective labeling agent for proteins aimed at facilitating their affinity purification and detection. Its multifaceted role spans across understanding protein-protein interactions, molecular biology, and oncology whereby its application in the development of diagnostic assays for cancer has proven resourceful. Synonyms: N-(3-Azidopropyl)biotinamide; biotin-azide. CAS No. 908007-17-0. Molecular formula: C13H22N6O2S. Mole weight: 326.42. | |
| Biotinoyl tripeptide-1 | Biotinoyl tripeptide-1 is a peptide beneficial for hair conditioning. Biotinoyl tripeptide-1 is also used in anti-aging cosmetics. Synonyms: (2S)-2-[[(2S)-2-[[2-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]acetyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-6-aminohexanoic acid. CAS No. 299157-54-3. Molecular formula: C24H38N8O6S. Mole weight: 566.67. | |
| Biotinyl-phenylboronic acid | Biotinyl-phenylboronic acid is the functionalized arylboronic acid of biotin used for palladium-catalyzed oxidative Heck reaction to protein-bound alkenes and Suzuki-Miyaura cross-coupling for labeling of protein bound phenylhalides in high yields and with excellent chemoselectivity. Synonyms: [3-[5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl)pentanoylamino]phenyl]boronic acid. Grades: 99%. CAS No. 1661014-48-7. Molecular formula: C16H22BN3O4S. Mole weight: 363.24. | |
| Bioymifi | Bioymifi is a potent and selective death receptor 5 (DR5) activator. Bioymifi works by mimicking the ability of TRAIL to stimulate clustering of DR5, triggering apoptosis. Bioymifi caused apoptosis and cell death in a variety of human cancer cell lines. Synonyms: DR5 Activator. Grades: >98%. CAS No. 1420071-30-2. Molecular formula: C22H12BrN3O4S. Mole weight: 494.32. | |
| Biricodar | Biricodar, also known as VX-710 or INCEL, is a novel compound that binds directly to P-gp. VX-710 concentrations of 0.5 to 2.5 M are sufficient to fully restore sensitivity of P-gp expressing cells to the cytotoxic action of paclitaxel and other cytotoxic drugs associated with the MDR phenotype. Synonyms: 1,7-dipyridin-3-ylheptan-4-yl (2S)-1-[2-oxo-2-(3,4,5-trimethoxyphenyl)acetyl]piperidine-2-carboxylate; biricodar; Incel; N-(2-oxo-2-(3,4,5-trimethoxyphenyl)acety)piperidine-2-carboxylic acid 1,7-bis(3-pyridyl)-4-heptyl ester; VX-710; VX 710; VX710; Biricodar; Incel. CAS No. 159997-94-1. Molecular formula: C34H41N3O7. Mole weight: 603.71. | |
| BIRT 377 | BIRT 377 is a negative allosteric modulator of LFA-1 (lymphocyte function-associated antigen-1) (Kd = 26 nM), which is involved in some important immunological events. BIRT 377 reversibly inhibits LFA-1 mediated binding of SKW3 leukemia cells to ICAM-1, and inhibits superantigen (SEB)-induced IL-2 production from lymphocytes in vitro and attenuates the SEB-induced increase in IL-2 plasma levels in a mouse model in vivo. Synonyms: BIRT-377; BIRT 377; BIRT377; (5R)-5-[(4-Bromophenyl)methyl]-3-(3,5-dichlorophenyl)-1,5-dimethyl-2,4-imidazolidinedione; (R)-5-(4-bromobenzyl)-3-(3,5-dichlorophenyl)-1,5-dimethylimidazolidine-2,4-dione. Grades: ≥98% by HPLC. CAS No. 213211-10-0. Molecular formula: C18H15BrCl2N2O2. Mole weight: 442.13. | |
| Bis[1,3-bis(h2-ethenyl)-1,1,3,3-tetramethyldisiloxane]platinum | Grades: 95%. CAS No. 81032-58-8. Molecular formula: C16H36O2PtSi4. Mole weight: 567.87. | |
| BIS(1-BUTYLPENTYL) DECANE-1,10-DIYL DIGLUTARATE | Abbreviated as Sec or U, in older publications also as Se-Cys, as a building block of selenoproteins, this 21st proteinogenic amino acid exists naturally in three domains of life, but not in every lineage. Uses: Used for the characterization of total sodium concentration in human blood plasma; also used for the preparation of nitrite-selective membrane electrode, used for the potentiometric determination of nad(p)h coenzymes. Synonyms: 5-O-nonan-5-yl 1-O-[10-(5-nonan-5-yloxy-5-oxopentanoyl)oxydecyl] pentanedioate; ETH 469; AC1ND8J0; 30585_FLUKA; ETH-469; ZINC100650269; 5-O-nonan-5-yl 1-O-[10-(5-nonan-5-yloxy-5-oxopentanoyl)oxydecyl] pentanedioate. Grades: ≥ 95.0%. CAS No. 101342-76-1. Molecular formula: C38H70O8. Mole weight: 654.96. | |
| Bis(2-cyanoethyl)-N,N-diisopropylphosphoramidite | A useful phosphorylating reagent. Synonyms: N,N-bis(1-Methylethyl)phosphoramidous acid bis(2-cyanoethyl) ester; Bis(2-cyanoethyl) diisopropylphosphoramidite; Bis (2-cyanoethoxy) (diisopropylamino)phosphine; Bis(2-cyanoethoxy)-N,N-diisopropylaminophosphine; Phosphoramidous acid, bis(1-methylethyl)-, bis(2-cyanoethyl) ester; Phosphoramidous acid, N,N-bis(1-methylethyl)-, bis(2-cyanoethyl) ester. Grades: 96%. CAS No. 102690-88-0. Molecular formula: C12H22N3O2P. Mole weight: 271.30. | |
| Bis(2-ethylhexyl) carbonate | Bis(2-ethylhexyl) carbonate (CAS# 14858-73-2 ) is a useful research chemical. Synonyms: Bis-(2-ethylhexyl) carbonate; diethylhexyl carbonate; Carbonic acid, bis(2-ethylhexyl) ester. CAS No. 14858-73-2. Molecular formula: C17H34O3. Mole weight: 286.4. | |
| bis-(4-(1,1,3,3-Tetramethylbutyl)phenyl) ether | Bis-(4-(1,1,3,3-Tetramethylbutyl)phenyl) ether is a highly valuable compound for the pharmaceutical industry due to its significance as a key intermediate. The synthesis of drugs and compounds for the treatment of a myriad of diseases depends on the use of bis-(4-(1,1,3,3-Tetramethylbutyl)phenyl) ether. Its versatility lies in its utilization as a crucial material in developing anti-inflammatory, antiviral agents, and inhibition of enzymes and receptors. The incorporation of this compound in drug formulations has immense implications for the healthcare industry. Synonyms: 1,1'-Oxybis[(1,1,3,3-tetramethylbutyl)benzene]; p-t-octylphenyl ether; 2,2,4-trimethyl-4-[4-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]phenyl]pentane; 1,1'-Oxybis[4-(1,1,3,3-tetramethylbutyl)benzene]; 1,1'-Oxybis[4-(2,4,4-trimethylpentan-2-yl)benzene]. Grades: 95%. CAS No. 101-58-6. Molecular formula: C28H42O. Mole weight: 394.63. | |
| Bis(4-fluorophenyl)phenylphosphine oxide | Catalyst for hydroformylation reactions Used for preparation of chlorine-tolerant polymers for desalination Crosslinking agent in preparation of polymer electrolyte membranes for fuel cell applications. Synonyms: Bis(4-fluorophenyl)phenylphosphineoxide. Grades: 97%. CAS No. 54300-32-2. Molecular formula: C18H13F2OP. Mole weight: 314.27. | |
| bis[6-(5,6-dihydrochelerythrinyl)]amine | Bis[6-(5,6-dihydrochelerythrinyl)]amine is found in Zanthoxylum nitidum, which shows strong activity against Aspergillus fumigatus and methicillin-resistant Staphylococcus aureus. Synonyms: 13,13'-Iminobis(1,2-dimethoxy-12-methyl-12,13-dihydro[1,3]benzodioxolo[5,6-c]phenanthridine); Bis(1,2-dimethoxy-12-methyl-12,13-dihydro-[1,3]dioxolo[4',5':4,5]benzo[1,2-c]phenanthridin-13-yl)amine. Grades: > 95%. CAS No. 165393-48-6. Molecular formula: C42H37N3O8. Mole weight: 711.76. | |
| Bisegliptin | Bisegliptin is an antidiabetic agent, but no detailed information has been published yet. Uses: Antidiabetic agent. Synonyms: ethyl 4-((2-((2S,4S)-2-cyano-4-fluoropyrrolidin-1-yl)-2-oxoethyl)amino)bicyclo[2.2.2]octane-1-carboxylate. Grades: 98%. CAS No. 862501-61-9. Molecular formula: C18H26FN3O3. Mole weight: 351.42. | |
| Bis(N-diazo)-tris(O-acetyl)-2-deoxystreptamine | Bis(N-diazo)-tris(O-acetyl)-2-deoxystreptamine (CAS# 90852-19-0 ) is a useful research chemical. Synonyms: [(1S,3R,4S,6R)-2,3-diacetyloxy-4,6-diazidocyclohexyl] acetate. CAS No. 90852-19-0. Molecular formula: C12H16N6O6. Mole weight: 340.29. | |
| bis-N-Succinimidyl diglycolic acid | Bis-N-Succinimidyl diglycolic acid, a widely utilized cross-linking reagent, plays a pivotal role in biomedicine. Its reaction with proteins' primary amines leads to covalent binding, which is instrumental in exploring protein-protein interactions. This reagent is also an indispensable component in the development of drug delivery and biomaterials to combat various diseases, including cancer. Synonyms: Bis-N-succinimidyl diglycolic acid, 2,2-Oxydiacetic acid bis-N-succinimidyl ester; DIG(NHS)2. Grades: 95%. CAS No. 373614-12-1. Molecular formula: C12H12N2O9. Mole weight: 328.232. | |
| Bisoprolol Acid Impurity | Bisoprolol Acid Impurity is a major metabolite and impurity of Bisoprolol, a medication used for the treatment of hypertension, heart failure and other heart diseases. Synonyms: 4-(2-Hydroxy-3-isopropylaminopropoxy)benzoic Acid. Grades: > 95%. CAS No. 72570-70-8. Molecular formula: C13H19NO4. Mole weight: 253.30. | |
| Bisoprolol EP Impurity A | isoprolol EP Impurity A is a metabolite of Metoprolol and Bisoprolol. Bisoprolol is a medication used for the treatment of hypertension, heart failure and other heart diseases. Synonyms: Des(isopropoxyethyl) Bisoprolol; 4-[2-Hydroxy-3-[ (1-Methylethyl) aMino]propoxy]benzeneMethanol. Grades: > 95%. CAS No. 62572-93-4. Molecular formula: C13H21NO3. Mole weight: 239.32. | |
| Bisoprolol EP Impurity G | An impurity of Bisoprolol, a medication used for the treatment of hypertension, heart failure and other heart diseases. Synonyms: rac Des(isopropoxyethyl)-2-isopropoxyethoxymethyl Bisoprolol; 1-[4-[[ (2-Isopropoxyethoxy) methoxy]methyl]phenoxy]-3-isopropylamino-2-propanol. Grades: > 95%. CAS No. 1215342-36-1. Molecular formula: C19H33NO5. Mole weight: 355.48. | |
| Bisoprolol EP Impurity K | Bisoprolol EP Impurity K is an impurity of Bisoprolol, a medication used for the treatment of hypertension, heart failure and other heart diseases. Synonyms: Keto Bisoprolol; 2-Isopropoxyethyl-4-[[(2RS)-2-hydroxy-3-(isopropylaMino)propyl]oxy]benzoate; 4-[2-hydroxy-3-[(1-Methylethyl)aMino]propoxy]-Benzoic Acid 2-(1-Methylethoxy)ethyl Ester. Grades: > 95%. CAS No. 864544-37-6. Molecular formula: C18H29NO5. Mole weight: 339.44. | |
| Bisoprolol EP Impurity L | Bisoprolol EP Impurity L is an impurity of Bisoprolol, which is a medication used for the treatment of hypertension, heart failure and other heart diseases. Synonyms: 4-[[(2RS)-2-hydroxy-3-(isopropylamino)propyl]oxy]-benzaldehyde; 4-[2-Hydroxy-3-[ (1-methylethyl) amino]propoxy]benzaldehyde; p-[2-Hydroxy-3- (isopropylamino) propoxy]benzaldehyde; Benzaldehyde, 4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-; H 128/80; Benzaldehyde, p-[2-hydroxy-3-(isopropylamino)propoxy]-; 4- (2-Hydroxy-3- (isopropylamino) propoxy) benzaldehyde; Metoprolol EP Impurity C; Metoprolol Impurity C. Grades: ≥95%. CAS No. 29122-74-5. Molecular formula: C13H19NO3. Mole weight: 237.29. | |
| Bisoprolol fumarate | Cas No. 104344-23-2. | |
| Bitoscanate | Bitoscanate is an organic chemical compound used in the treatment of hookworms. Uses: Used in the treatment of hookworms. Synonyms: Bitoscanate; 16842; Bitoscanatum; Hoe 16842; Phenylene thiocyanate; AI3-28258; HSDB 6435;; 1,4-Diisothiocyanatobenzene;1,4-Phenylene diisothiocyanate. Grades: ≥95%. CAS No. 4044-65-9. Molecular formula: C8H4N2S2. Mole weight: 192.26. | |
| BIX 02565 | BIX 02565, a RSK2 inhibitor, has also been found to significanltly influence sorts of adrenergic receptor subtypes involved in ascular tone and cardiac function. IC50: 1.1 nM (RSK2). Uses: Bix 02565 is a rsk2 inhibitor that has also been found to significanltly influence sorts of adrenergic receptor subtypes involved in ascular tone and cardiac function. Synonyms: BIX 02565; BIX02565; CHEMBL1933288; BIX02565; GTPL8039; SCHEMBL1980595; BDBM50360301. Grades: 97%. CAS No. 1311367-27-7. Molecular formula: C26H30N6O2. Mole weight: 458.56. | |
| BIX NHE1 inhibitor | BIX NHE1 inhibitor is a potent and selective NHE1 inhibitor (IC50 = 31 nM). It attenuates ischemic damage in an ischemia reperfusion injury isolated rat heart model ex vivo, attenuates phenylephrine-induced cardiomyocyte hypertrophy in vitro. Synonyms: BI-9627; BI 9627; BI9627; 4-(1-Acetyl-4-piperidinyl)-N-(aminoiminomethyl)-3-(trifluoromethyl)benzamide hydrochloride. Grades: ≥98% by HPLC. CAS No. 1204329-34-9. Molecular formula: C16H19F3N4O2.HCl. Mole weight: 392.8. | |
| Bizine | Lysine-specific demethylase 1 (LSD1) is an epigenetic enzyme, which can oxidatively cleave methyl groups from monomethyl and dimethyl Lys4 of histone H3. Bizine is an LSD1 inhibitor, which is a phenelzine analog that inhibits lysine-specific demethylase 1 with ki of 59 nM. It is 23-fold, 63-fold, and >100-fold selective for LSD-1 over monoamine oxidase (MAO) A, MAOB, and LSD2, respectively. Synonyms: BSM-0353. Grades: ≥95%. CAS No. 1591932-50-1. Molecular formula: C18H23N3O. Mole weight: 297.4. | |
| Bizine hydrochloride | Bizine hydrochloride is a potent and selective histone demethylase LSD1 inhibitor. Bizine can modulate bulk histone methylation in cancer cells and protect neurons exposed to oxidative stress, suggesting potential applications in neurodegenerative disease. Uses: Potential neurodegenerative disease therapy. Synonyms: N-[4-(2-hydrazinylethyl)phenyl]-4-phenylbutanamide hydrochloride. Grades: 98%. Molecular formula: C18H23N3O.HCl. Mole weight: 333.86. | |
| BKT140 | BKT140 is a CXCR4 inhibitor with antineoplastic activity. Studies demonstrated that BKT140 showed a robust mobilization of white blood cells (WBC) and hematopoietic stem cells (HSC). Synonyms: BL-8040; Motixafortide; 4F-benzoyl-TN14003. Grades: 98%. CAS No. 664334-36-5. Molecular formula: C97H144FN33O19S2. Mole weight: 2159.55. | |
| (-)-Blebbistatin | (-)-Blebbistatin is a cell-permeable inhibitor for non muscle myosin II ATPase with IC50 of ~2 μM, does not inhibit myosin light chain kinase, inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. Synonyms: (S)-(-)-Blebbistatin; (S)-blebbistatin; (3aS)-3a-hydroxy-6-methyl-1-phenyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-one. Grades: >98%. CAS No. 856925-71-8. Molecular formula: C18H16N2O2. Mole weight: 292.33. | |
| Blinin | Blinin is a diterpene originally isolated from C. blini. Uses: Antimalarial. Synonyms: 4-[2-[(1S,2R,4aS,7S,8aR)-4a-[(Acetyloxy)methyl]-1,2,3,4,4a,7,8,8a-octahydro-7-hydroxy-5-(hydroxymethyl)-1,2-dimethyl-1-naphthalenyl]ethyl]-2(5H)-furanone; 2(5H)-Furanone, 4-[2-[(1S,2R,4aS,7S,8aR)-4a-[(acetyloxy)methyl]-1,2,3,4,4a,7,8,8a-octahydro-7-hydroxy-5-(hydroxymethyl)-1,2-dimethyl-1-naphthalenyl]ethyl]-; 4-[2-[(1S,2R,4aS,7S,8aR)-4a-[(Acetyloxy)methyl]-1,2,3,4,4a,7,8,8a-octahydro-7-hydroxy-5-(hydroxymethyl)-1,2-dimethyl-1-naphthalenyl]ethyl]-2(5H)-furanone. Grades: >98%. CAS No. 125675-09-4. Molecular formula: C22H32O6. Mole weight: 392.49. | |
| BLU-554 | BLU-554 is a potent and selective inhibitor of fibroblast growth factor receptor 4 (FGFR4) (IC50 = 5 nM), which is promisingly to be used for the treatment of hepatocellular carcinoma and cholangiocarcinoma. Synonyms: BLU-554; BLU 554; BLU554, Fisogatinib; SCHEMBL16668287; EX-A841; MFCD30496704; N-[(3S,4S)-3-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)quinazolin-2-yl]amino]oxan-4-yl]prop-2-enamide; BLU554. Grades: 99.08 %. CAS No. 1707289-21-1. Molecular formula: C24H24Cl2N4O4. Mole weight: 503.38. | |
| BLU9931 | BLU9931 is a potent and irreversible small-molecule inhibitor of FGFR4, as a targeted therapy to treat patients with HCC whose tumors have an activated FGFR4 signaling pathway. BLU9931 is exquisitely selective for FGFR4 versus other FGFR family members and all other kinases. Synonyms: BLU9931; BLU-9931; BLU 9931. Grades: 98%. CAS No. 1538604-68-0. Molecular formula: C26H22Cl2N4O3. Mole weight: 509.38. | |
| BM 567 | Thromboxane A2 (TXA2) is a potent thrombogenic and vasoconstrictor eicosanoid. It has been reported as a causal factor in the onset of stroke and myocardial infarction. BM 567 is a dual acting antithrombogenic agent, which is acting as an inhibitor of thromboxane A2 (TXA2) synthase and an antagonist of the TP receptor. It also antagonizes the vascular smooth muscle TP receptor with an IC50 value of 1.1 nM. Synonyms: BM567; BM-567. Grades: ≥98%. CAS No. 284464-77-3. Molecular formula: C18H28N4O5S. Mole weight: 412.5. | |
| BML 111 | BML 111 is a FPR2 (lipoxin A4 receptor) agonist. It inhibits tumor-related angiogenesis and reduces tumor growth in hepatoma H22 cell bearing mice. BML 111 also protects against hemorrhagic shock-induced acute lung injury in rats and attenuates renal ischemia/reperfusion injury. Synonyms: BML-111; BML 111; BML111. (5S,6R)-Methyl 5,6,7-trihydroxyheptanoate; methyl (5S,6R)-5,6,7-trihydroxyheptanoate. CAS No. 78606-80-1. Molecular formula: C8H16O5. Mole weight: 192.21. | |
| BML-284 | BML-284 is potent, selective and cell-permeable Wnt signaling activator. It induces β-catenin and transcription factor (TCF)-dependent transcriptional activity in 293T cells in a dose dependent manner with an EC50 of 0.7 mM in vitro. Uses: Bml-284 may be a useful tool in the study of physiological processes that involve the wnt pathway. Synonyms: BML 284; 2-Amino-4-(3,4-(methylenedioxy)benzylamino)-6-(3-methoxyphenyl)pyrimidine; 4-N-(1,3-benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)pyrimidine-2,4-diamine. Grades: >98%. CAS No. 853220-52-7. Molecular formula: C19H18N4O3. Mole weight: 350.37. | |
| BMP-22 | BMP-22 is an inhibitor of autotaxin with IC50 of 170 nM. It is selective for autotaxin over the phosphodiesterases NPP6 and NPP7 at 10 μM. BMP-22 inhibits autotaxin-mediated production of lysophosphatidic acid (LPA) from lysophosphatidylcholine (LPC) in vitro in a concentration-dependent manner. MP-22 can decrease the number of lung metastatic foci in a B16/F10 syngeneic mouse melanoma model of lung metastasis. Synonyms: 4-pentadecylbenzylphosphonic acid; BMP22; BMP 22. Grades: ≥95%. CAS No. 1306684-90-1. Molecular formula: C22H39O3P. Mole weight: 382.52. | |
| BMPS | Cas No. 55750-62-4. | |
| BMS 181168 | This active molecular is an potential cognitive enhancer originated by Bristol-Myers Squibb. Mechanism of Action is not identified. Bmy 21502 is also a nootropic agent and it can protect rodents from ECS-induced amnesia in a step-down passive avoidance task. But clinical study for treatment of Alzheimer's disease was discontinued. Uses: Alzheimer's disease. Synonyms: Bmy 21502; Bmy21502; Bmy-21502; Bms-181168; Bms 181168; Bms181168. 1-((1-(2-(trifluoromethyl)pyrimidin-4-yl)piperidin-4-yl)methyl)pyrrolidin-2-one. Grades: 98%. CAS No. 123259-91-6. Molecular formula: C15H19F3N4O. Mole weight: 328.34. | |
| BMS 182264 | BMS 182264 is a bio-active chemical, but few detailed information has been published yet. Synonyms: BMS 182264; BMS-182264; BMS182264; CHEMBL19169; N-Cyano-N'-(4-cyanophenyl)-N''-1,2,2-trimethylpropylguanidine. Grades: 98%. CAS No. 127749-54-6. Molecular formula: C15H19N5. Mole weight: 269.35. | |
| BMS-186318 | BMS-186318 has been found to be a HIV protease inhibitor that was once studied against HIV by Bristol-Myers Squibb. Synonyms: BMS 186318; BMS-186318; BMS186318; 12-Oxa-2,6,10-triazatetradecanoic acid, 4,8-dihydroxy-13,13-dimethyl-3-((4-(2-(4-morpholinyl)-2-oxoethoxy)phenyl)methyl)-11-oxo-9-(phenylmethyl)-, 1,1-dimethylethyl ester, (3S,4R,8R,9S)-; BMS-186318 analog 19; 12-Oxa-2,6,10-triazat. Grades: 98%. CAS No. 161302-40-5. Molecular formula: C36H54N4O9. Mole weight: 686.85. | |
| BMS-187071 | BMS-187071 has been found to be a HIV protease inhibitor that was once studied against HIV by Bristol-Myers Squibb. Synonyms: BMS 187071; BMS187071; BMS187071; (3-((3-((2,3,3-Trimethyl-2(S)-2-hydroxy-1-oxobutyl)amino)-2-hydroxy-4-phenylbutyl)amino)-2-hydroxy-1-(phenylmethyl)propyl)carbamic acid, 1,1-dimethylethyl ester; [3-[[3-[(2,3,3-Trimethyl-2(S)-2-hydroxy-1-oxobutyl)amino]-2-hydroxy-4. Grades: 98%. CAS No. 161302-39-2. Molecular formula: C32H49N3O6. Mole weight: 571.75. | |
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