BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| R 892 | R 892 is a selective, highly potent, and metabolically stable bradykinin B1 receptor antagonist (ID50= 2.8 and > 600 nM at B1 and B2 receptors respectively). It may be useful for the assessment of the physiological and pathological roles of kinin B1 receptors. R 892 exhibits no intrinsic agonist activity and is resistant to aminopeptidase and kininase II (ACE) cleavage. Synonyms: R 892; R892; R-892; (1Z,4Z,6S,7Z,9S,10Z,12R,13Z,15S)-1-((S)-1-((S)-1-((S)-2-((Z)-((S)-6-amino-1-hydroxy-2-((Z)-(1-hydroxyethylidene)amino)hexylidene)amino)-5-guanidinopentanoyl)pyrrolidine-2-carbonyl)pyrrolidin-2-yl)-6-benzyl-15-((S)-sec-butyl)-1,4,7,10,13-pentahydroxy-9-(hy. Grade: >98%. CAS No. 229030-05-1. Molecular formula: C58H83N13O12. Mole weight: 1154.37. |  |
| R8-T198wt | R8-T198wt is a cell-permeable peptide inhibitor of Pim-1 kinase. It inhibits Pim-1 phosphorylation of p27Kip1 and Bad, and induces cell cycle arrest (at G1) and apoptosis in DU145 prostate cancer cells. R8-T198wt is possible that this peptide can also inhibit other kinases of the Pim family, such as Pim-2 and Pim-3, because not only Pim-1 but also Pim-2 and Pim-3 can directly phosphorylate p27Kip1 at the Thr198 residue. Synonyms: H-Gly-Gly-Gly-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Gly-Cys-Lys-Lys-Pro-Gly-Leu-Arg-Arg-Arg-Gln-Thr-OH. Grade: >95%. CAS No. 2305815-72-7. Molecular formula: C111H211N59O26S. Mole weight: 2820.33. | |
| Rabies Virus Glycoprotein | Rabies Virus Glycoprotein, a 29-amino-acid cell penetrating peptide derived from a rabies virus glycoprotein, is only structural protein of the virus that induces the formation of virus-neutralizing antibodies and which confers immunity to animals. Synonyms: Tyr-Thr-Ile-Trp-Met-Pro-Glu-Asn-Pro-Arg-Pro-Gly-Thr-Pro-Cys-Asp-Ile-Phe-Thr-Asn-Ser-Arg-Gly-Lys-Arg-Ala-Ser-Asn-Gly. Grade: ≥95%. Molecular formula: C141H217N43O43S2. Mole weight: 3266.67. | |
| Rac1 Inhibitor F56, control peptide | Rac1 Inhibitor F56, control peptide is a control peptide version of Rac1 Inhibitor. Synonyms: H-Met-Val-Asp-Gly-Lys-Pro-Val-Asn-Leu-Gly-Leu-Phe-Asp-Thr-Ala-Gly-OH. Grade: >98%. CAS No. 1315378-77-8. Molecular formula: C72H116N18O23S. Mole weight: 1632.89. | |
| Rac1 Inhibitor W56 | Rac1 Inhibitor W56 is a peptide comprising residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activation site of Rac1. Synonyms: FLA 870; FLA-870; FLA870; Raclopride tartrate; MVDGKPVNLGLWDTAG. Grade: >97%. CAS No. 1095179-01-3. Molecular formula: C74H117N19O23S. Mole weight: 1671.93. | |
| Rac-Selenobiotin | Selenobiotin as an excretion product of Phycomyces blakesleeanus. It is an excellent growth factor, as efficient as biotin in supporting the growth of biotin-requiring microorganisms. It is a biotin analog. Synonyms: Hexahydro-2-oxo-1H-selenolo[3,4-d]imidazole-4-pentanoic Acid. Grade: > 95%. CAS No. 57956-29-3. Molecular formula: C10H16N2O3Se. Mole weight: 291.21. | |
| (±)-Ractopamine-[d3] HCl (2-hydroxyethyl-[1,1,2-d3]) | An isotope lablled Ractopamine. Ractopamine is a feed additive to promote leanness in animals raised for their meat. Pharmacologically, it is a TAAR1 agonist and β adrenoreceptor agonist that stimulates β1 and β2 adrenergic receptors. Grade: 95% by HPLC; 98% atom D. CAS No. 1219794-72-5. Molecular formula: C18H21D3ClNO3. Mole weight: 340.87. | |
| Raffinose-sp-biotin | Raffinose-sp-biotin. | |
| RAGE antagonist peptide | RAGE antagonist peptide was produced as an inhibitor of the RAGE signaling pathway based on the RAGE-binding domain of high mobility group box-1 (HMGB1). It blocks S100P, S100A4 and HMGB-1 mediated RAGE activation in vitro and in vivo. Synonyms: Ac-Glu-Leu-Lys-Val-Leu-Met-Glu-Lys-Glu-Leu-NH2. CAS No. 1092460-91-7. Molecular formula: C57H101N13O17S. Mole weight: 1272.56. | |
| Ramoplanin | Ramoplanin complex is a complex of three high molecular weight glycolipopeptide peptides, the chain length and the shape of the diketene lipid side chain are different. It inhibits cell wall biosynthesis through a mechanism different from vancomycin-related glycopeptide. Synonyms: Ramoplanin; A 16686; A16686; A-16686; MD 62198; MD62198; MD-62198; MDL62198. Grade: >95% by HPLC. CAS No. 76168-82-6. Molecular formula: C106H170ClN21O30. Mole weight: 2254.06. | |
| Ramucirumab | Ramucirumab is a human IgG1 monoclonal antibody developed by ImClone Systems Inc to treat solid tumors. It has been approved by FDA for the treatment of advanced gastric or gastro-esophageal junction adenocarcinoma and metastatic non-small-cell lung carcinoma (NSCLC). Ramucirumab acts as a VEGFR2 antagonist via binding to VEGFR2. Uses: Antitumor agent. Synonyms: Cyramza; Imc 1121b. Grade: ≥98%. CAS No. 947687-13-0. Molecular formula: C6374H9864N1692O1996S46. Mole weight: 143609.63. | |
| Rapastinel | Rapastinel, a brain penetrable tetrapeptide, could be a partial agonist of NMDA receptor. It was already finished the Phase II trial for acting as an antidepressant agent. It was just planed a phase III trial for Major depressive disorder. Uses: Rapastinel is a brain penetrable tetrapeptide and could be a partial agonist of nmda receptor. Synonyms: GLYX-13; GLYX 13; GLYX13; BV-102; BV102; BV 102; TPPT-amide; Rapastinel; UNII-6A1X56B95E; GLYX-13 trifluoroacetate; TPPT-amide trifluoroacetate. Grade: ≥98% by HPLC. CAS No. 117928-94-6. Molecular formula: C18H31N5O6. Mole weight: 413.47. | |
| Rat CGRP-(8-37) | CGRP 8-37 (rat) is a peptide antagonist for CGRP1 receptors. Synonyms: Calcitonin Gene-Related Peptide 8-37 (rat); 8-37-a-Calcitoningene-related peptide (human reduced), 25-L-aspartic acid, 35-L-glutamic acid-; Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asp-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Glu-Ala-Phe-NH2; CGRP 8-37 rat; L-valyl-L-threonyl-L-histidyl-L-arginyl-L-leucyl-L-alanyl-glycyl-L-leucyl-L-leucyl-L-seryl-L-arginyl-L-seryl-glycyl-glycyl-L-valyl-L-valyl-L-lysyl-L-alpha-aspartyl-L-asparagyl-L-phenylalanyl-L-valyl-L-prolyl-L-threonyl-L-asparagyl-L-valyl-glycyl-L-seryl-L-alpha-glutamyl-L-alanyl-L-phenylalaninamide. Grade: ≥95%. CAS No. 129121-73-9. Molecular formula: C138H224N42O41. Mole weight: 3127.51. | |
| (R)-Bicalutamide-[d4] | (R)-Bicalutamide-[d4] is the labelled (R)-enantiomer of Bicalutamide. Bicalutamide is an antiandrogen drug commonly used for the treatment of prostate cancer. Synonyms: (R)-Bicalutamide D4; (2R)-N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl-d4)sulfonyl]-2-hydroxy-2-methylpropanamide; (R)-Casodex-d4. Grade: >95%. CAS No. 1217826-87-3. Molecular formula: C18H10D4F4N2O4S. Mole weight: 434.41. | |
| RC 160 | RC 160 is a cyclic octapeptide somatostatin analog (Ki= 0.7, 5.4, 30.9, 45 and > 1000 nM for sst5, sst2, sst3, sst4 and sst1 receptors respectively). RC 160 is a peptide neurokinin-1 receptor (NK1) antagonist and inhibits increases in vascular permeability stimulated by substance P in a concentration-dependent manner in isolated guinea pig trachea and main bronchi. It is used in the treatment of esophageal variceal bleeding in patients with cirrhotic liver disease and AIDS-related diarrhea. Uses: Antineoplastic agents. Synonyms: D-Phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-L-tryptophanamide, cyclic (2→7)-disulfide; BMY-41606; BMY 41606; BMY41606; RC160; RC-160; DP-05-094; Octastatin; L-Tryptophanamide, D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-, cyclic (2→7)-disulfide; RC 160 (protein); Vapreotide; D-Phe-Cys-Trp-D-Trp-Lys-Val-Cys-Trp-CONH2 (Disulfide bridge: Cys2-Cys7). Grade: 98%. CAS No. 103222-11-3. Molecular formula: C57H70N12O9S2. Mole weight: 1131.37. | |
| RC-3095 | RC-3095 is a bombesin/gastrin-releasing peptide (BN/GRP) antagonist with potential anticancer activity. Synonyms: [D-Tpi6, Leu13 psi(CH2NH)-Leu14]bombesin-(6-14); (S)-N1-((2S,5S,8S,14S,17S,20S)-14-((1H-imidazol-5-yl)methyl)-20-carbamoyl-1-(1H-indol-3-yl)-17-isobutyl-8-isopropyl-5,22-dimethyl-3,6,9,12,15-pentaoxo-4,7,10,13,16,19-hexaazatricosan-2-yl)-2-((R)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxamido)pentanediamide; N2-[(3R)-2,3,4,9-Tetrahydro-1H-β-carbolin-3-ylcarbonyl]-L-glutaminyl-L-tryptophyl-L-alanyl-L-valylglycyl-N-[(2S)-1-{[(2S)-1-amino-4-methyl-1-oxo-2-pentanyl]amino}-4-methyl-2-pentanyl]-L-histidina mide. Grade: ≥95%. CAS No. 138147-78-1. Molecular formula: C56H79N15O9. Mole weight: 1106.32. | |
| (R)-Cetirizine-[d4] Dihydrochloride | (R)-Cetirizine-[d4] Dihydrochloride is the labelled salt of Levocetirizine, which is a histamine H1 receptor antagonist and could be used as an antihystaminic agent. Synonyms: Levocetirizine D4 Dihydrochloride; 2-[2-[4-[(R)-(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy-d4]acetic Acid Dihydrochloride; (-)-Cetirizine-d4 Dihydrochloride. Grade: 98% by CP; 98% atom D. Molecular formula: C21H23D4Cl3N2O3. Mole weight: 465.83. | |
| (R)-Cinacalcet-[d3] | (R)-Cinacalcet-D3 is a labelled analogue of Cinacalcet. Cinacalcet is a calcimimetic activating the calcium-sensing receptor. It is indicated for the treatment of secondary hyperparathyroidism and hypercalcemia in patients with parathyroid gland cancer. Synonyms: (R)-Cinacalcet D3. Grade: 98% by HPLC; 99% atom D. CAS No. 1228567-12-1. Molecular formula: C22H19D3F3N. Mole weight: 360.43. | |
| (R)-Cinacalcet-[d3] Hydrochloride | (R)-Cinacalcet-[d3] Hydrochloride is the labelled salt of (R)-Cinacalcet. Cinacalcet is the first calcimimetic drug approved by the United States Food and Drug Administration for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease. Synonyms: (R)-Cinacalcet-D3 Hydrochloride; (R)-α-(Methyl-d3)-N-[3-[3-(trifluoromethyl)phenyl)propyl]-1-napthalenemethanamine Hydrochloride; (R)-N-(3-(3-(trifluoromethyl)phenyl)propyl)-1-(1-napthyl)ethylamine-d3 Hydrochloride; Mimpara-d3; Sensipar-d3; Cinacalcet-d3 Hydrochloride. Grade: ≥98% by HPLC; 99% atom D. Molecular formula: C22H20D3ClF3N. Mole weight: 396.89. | |
| (R)-Citalopram-[d4] Oxalate | (R)-Citalopram-[d4] Oxalate is the labelled analogue of (R)-Citalopram Oxalate. (R)-Citalopram Oxalate is an inhibitor of serotonin (5-HT) uptake. It shows antidepressant activity. Synonyms: (-)-(R)-Citalopram-d4 Oxalate; (R)-Citalopram Oxalate-d4; 1-(3-Dimethylaminopropyl)-1-(4-fluoro-phenyl)-1,3-dihydro-isobenzofuran-5-carbonitrile-d4 Oxalate; Escitalopram EP Impurity K-d4. Grade: 98% by HPLC. Molecular formula: C20H17D4FN2O.C2H2O4. Mole weight: 418.45. | |
| (R)-Crizotinib-[d5] (piperidine-[3,3,4,5,5-d5]) | One of the isotopic labelled form of (R)-Crizotinib, which is probably be a potent ALK inhibitor as well as c-MET inhibitor. Synonyms: (R)-3-[1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)pyridin-2-ylamine. Grade: 95% by HPLC; 98% atom D. CAS No. 1395950-84-1. Molecular formula: C21H17D5Cl2FN5O. Mole weight: 455.37. | |
| (R)-Darifenacin-[d4] Hydrobromide | (R)-Darifenacin-[d4] Hydrobromide is the labelled salt of (R)-Darifenacin, which is the enantiomeric impurity of Darifenacin, a medication used to treat urinary incontinence. Synonyms: (R)-Darifenacin-d4 Hydrobromide; (3R)-1-[2-(2,3-Dihydro-5-benzofuranyl)ethyl]-α-α-diphenyl-3-pyrrolidineacetamide-d4 Hydrobromide; ent-Darifenacin-d4 Hydrobromide. Grade: >95%. CAS No. 1261394-25-5. Molecular formula: C28H27D4BrN2O2. Mole weight: 511.49. | |
| ReACp53 | ReACp53 is a cell-permeable inhibitor of p53 amyloid formation that targets mutant p53 protein in primary prostate cancer. Synonyms: H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Pro-Ile-Leu-Thr-Arg-Ile-Thr-Leu-Glu-OH; L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-prolyl-L-isoleucyl-L-leucyl-L-threonyl-L-arginyl-L-isoleucyl-L-threonyl-L-leucyl-L-glutamic acid. Grade: ≥95%. Molecular formula: C108H206N52O24. Mole weight: 2617.13. | |
| ReACp53 acetate | ReACp53 acetate is an acetate form of ReACp53 that is a cell-penetrating peptide, used to inhibit p53 amyloid formation in cancer cell lines. Grade: >98.0%. Molecular formula: C110H210N52O26. Mole weight: 2677.18. | |
| rec IGF-II (1-67) (human) | IGF-II appears to be specifically involved in fetal growth, but otherwise shows similar biological activity to IGF-I (approx. ED50 = 0.1 ng/mL). Synonyms: H-Ala-Tyr-Arg-Pro-Ser-Glu-Thr-Leu-Cys-Gly-Gly-Glu-Leu-Val-Asp-Thr-Leu-Gln-Phe-Val-Cys-Gly-Asp-Arg-Gly-Phe-Tyr-Phe-Ser-Arg-Pro-Ala-Ser-Arg-Val-Ser-Arg-Arg-Ser-Arg-Gly-Ile-Val-Glu-Glu-Cys-Cys-Phe-Arg-Ser-Cys-Asp-Leu-Ala-Leu-Leu-Glu-Thr-Tyr-Cys-Ala-Thr-Pro-Ala-Lys-Ser-Glu-OH. Grade: ≥95%. CAS No. 96081-16-2. Molecular formula: C321H499N93O101S6. Mole weight: 7469.41. | |
| Reductiomycin | Reductiomycin is produced by the strain of Str. griseorubiginosus S551. It can resist gram-positive bacteria, fungi and some yeast. It also inhibits the proliferation of chicken Newcastle disease virus. Synonyms: AM 6201; Alkaloid AM 6201; Antibiotic S 551II; Antibiotic AM 6201; BRN 4525860; (E)-4-(3-((2-hydroxy-5-oxocyclopent-1-en-1-yl)amino)-3-oxoprop-1-en-1-yl)-2,3-dihydrofuran-2-yl acetate. CAS No. 68748-55-0. Molecular formula: C14H15NO6. Mole weight: 293.27. | |
| Regorafenib | Regorafenib, also known as BAY 73-4506, is an orally bioavailable small molecule with potential antiangiogenic and antineoplastic activities. Regorafenib binds to and inhibits vascular endothelial growth factor receptors (VEGFRs) 2 and 3, and Ret, Kit, PDGFR and Raf kinases, which may result in the inhibition of tumor angiogenesis and tumor cell proliferation. VEGFRs are receptor tyrosine kinases that play important roles in tumor angiogenesis; the receptor tyrosine kinases RET, KIT, and PDGFR, and the serine/threonine-specific Raf kinase are involved in tumor cell signaling. Regorafenib is demonstrated to increase the overall survival of patients with metastatic colorectal cancer and has been approved by the US FDA on September 27, 2012. Uses: Antineoplastic agent. Synonyms: 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide; 4-[4-[N'-(4-Chloro-3-trifluoromethylphenyl)ureido]-3-fluorophenoxy]pyridine-2-carboxylic Acid Methylamide; Regorafenibum; Stivarga; 4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-methylpicolinamide; BAY 73-4506; BAY 734506; BAY734506; BAY-734506. Grade: >98%. CAS No. 755037-03-7. Molecular formula: C21H15ClF4N4O3. Mole weight: 482.83. | |
| RES-701-1 | RES-701-1 is an endothelin type B receptor antagonist produced by Streptomyces sp. RE-701. It selectively inhibits the ET-1 binding to endothelin type B receptor. Uses: Endothelin receptor antagonists. Synonyms: GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-ASP-TRP-PHE-PHE-ASN-TYR-TYR-TRP; GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-ASP-TRP-PHE-PHE-ASN-TYR-TYR-TRP-OH; CYCLO(-GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-ASP)-TRP-PHE-PHE-ASN-TYR-TYR-TRP-OH; CYCLO(-GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-BETA-ASP). Grade: 95%. CAS No. 151308-34-8. Molecular formula: C103H115N23O23. Mole weight: 2043.16. | |
| Resistoflavine | A rare, boat-shaped, pentacyclic polyketide isolated from several species of streptomyces; exhibits weak antibacterial activity against gram-positive and gram-negative bacteria; exhibits potent cytotoxic activity against tumour cell lines in vitro; inhibits growth, and nucleic acid and protein synthesis in bacillus subtilis. Synonyms: Resistoflavin; BRN 2491848; (-)-3,5,7,11b-Tetrahydroxy-1,1,9-trimethyl-2H-benzo(cd)pyrene-2,6,10(1H,11bH)-trione. Grade: >98% by HPLC. CAS No. 29706-96-5. Molecular formula: C22H16O7. Mole weight: 392.36. | |
| Resorcinomycin A | Resorcinomycin A is produced by the strain of Streptoverticillum roseoverticillatum. It has strong anti-mycobacterium effect and weak anti-mycoplasma effect. Synonyms: N-(alpha-Guanidino-3,5-dihydroxy-4-isopropylphenylacetyl)glycine; S-Resorcinomycin A; (S)-(2-((diaminomethylene)amino)-2-(3,5-dihydroxy-4-isopropylphenyl)acetyl)glycine. Grade: 95%. CAS No. 100234-70-6. Molecular formula: C14H20N4O5. Mole weight: 324.33. | |
| Retapamulin | Retapamulin (SB-275833) is a topical antibiotic, which binds to both E. coli and S. aureus ribosomes with similar potencies with Kd of 3 nM. Uses: For research use only. Synonyms: [(3-exo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl]thio]acetic Acid; [(3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl Ester; Altabax; Altargo; Mutilin; 14-(exo-8-Methyl-8-azabicyclo[3.2.1]oct-3-ylsulfanyl)acetate; SB-275833; SB275833; SB 275833. Grade: 97%. CAS No. 224452-66-8. Molecular formula: C30H47NO4S. Mole weight: 517.76. | |
| Retatrutide | Retatrutide is a triple glucagon, GIP, and GLP-1 receptor agonist. Retatrutide showed glucose control and weight loss in patients with type 2 diabetes mellitus (T2DM). Uses: Retatrutide is a new peptide medication that has showed great promise in drug discovery because of its distinct mode of action and its medicinal uses. the high specificity and affinity of retitrutide for its target receptors is one of the main characteristics that make it an attractive option for drug discovery. this peptide is engineered to bind specifically to specific cell surface receptors, th. Synonyms: LY3437943; LY 3437943; LY-3437943. Grade: 98% by HPLC. CAS No. 2381089-83-2. Molecular formula: C221H342N46O68. Mole weight: 4731.33. | |
| RETF-4NA | RETF-4NA is a sensitive substrate for chymase when free or bound to α2M. It is selectively hydrolyzed by chymase but not by cathepsin G. Synonyms: acetyl-L-Arg-Glu-Thr-Phe-4-nitroanilide. CAS No. 1160928-63-1. Molecular formula: C32H43N9O10. Mole weight: 713.75. | |
| (R)-(-)-Etodolac-[d3] | (R)-(-)-Etodolac-[d3] is the labelled R-enantiomer of Etodolac. Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2. Synonyms: (R)-(-)-Etodolac D3; (1R)-1,8-(Diethyl-d3)-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic Acid; (-)-(R)-Etodolac-d3; (-)-Etodolac-d3; (-)-Etodolic Acid-d3; R-Etodolac-d3. Grade: >95%. CAS No. 1246815-33-7. Molecular formula: C17H18D3NO3. Mole weight: 290.38. | |
| Retrocyclin-1 | Retrocyclin-1, a theta-defensin, is a circular octadecapeptide containing an internal trisulfide ladder. In addition to its antimicrobial activity, it has a significant in vitro ability to protect human cells from infection with the T- and M-tropic strains of HIV-1. Retrocyclin is a small molecule HIV-1 entry inhibitor. Synonyms: RC-100; Cyclo(-Gly-Ile-Cys-Arg-Cys-Ile-Cys-Gly-Arg-Gly-Ile-Cys-Arg-Cys-Ile-Cys-Gly-Arg) (Disulfide bridge: Cys3-Cys16, Cys5-Cys14, Cys7-Cys12); cyclo[L-arginyl-L-cysteinyl-L-isoleucyl-L-cysteinyl-glycyl-L-arginyl-glycyl-L-isoleucyl-L-cysteinyl-L-arginyl-L-cysteinyl-L-isoleucyl-L-cysteinyl-glycyl-L-arginyl-glycyl-L-isoleucyl-L-cysteinyl] (2->11),(4->9),(13->18)-tris(disulfide). Grade: ≥95%. CAS No. 724760-19-4. Molecular formula: C74H128N30O18S6. Mole weight: 1918.39. | |
| Reveromycin B | Reveromycin B is a polyketide antibiotic isolated from Streptomyces, which can inhibit mitotic activity. Synonyms: BDBM50217842; ZINC49871994. Grade: >98% by HPLC. CAS No. 144860-68-4. Molecular formula: C36H52O11. Mole weight: 660.79. | |
| Reveromycin C | Reveromycin C is a polyketide isolated from Streptomyces. It is an antibiotic inhibitor with mitotic activity that responds to EGF. Grade: >95% by HPLC. CAS No. 144860-69-5. Molecular formula: C37H54O11. Mole weight: 674.82. | |
| Rezafungin | Rezafungin, a next-generation, broad-spectrum and long-lasting echinocandin, has potent antifungal activity against Candida spp., Aspergillus spp. and Pneumocystis spp. Synonyms: Biafungin; CD101; SP-3025; 2-{[(2R,6S,9S,11R,12S,14aS,15S,16S,20S,23S,25aS)-23-[(1S,2S)-1,2-Dihydroxy-2-(4-hydroxyphenyl)ethyl]-2,11,15-trihydroxy-6,20-bis[(1R)-1-hydroxyethyl]-16-methyl-5,8,14,19,22,25-hexaoxo-9-({[4''-(pentyloxy)-1,1':4',1''-terphenyl-4-yl]carbonyl}amino)tetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-12-yl]oxy}-N,N,N-trimethylethanaminium. Grade: ≥95%. CAS No. 1396640-59-7. Molecular formula: C63H85N8O17+. Mole weight: 1226.39. | |
| RF 9 | RF 9 is a potent and selective Neuropeptide FF receptor antagonist, with Kis of 58±5 and 75±9 nM for hNPFF1R and hNPFF2R, respectively. It displays selectivity over several related receptors including NPY Y1 GPR10, GPR54, GPR103 and the opioid receptors. Synonyms: 2-Adamantanecarbonyl-Arg-Phe-NH2. Grade: ≥96%. CAS No. 876310-60-0. Molecular formula: C26H38N6O3. Mole weight: 482.62. | |
| RFRP-2 (rat) | RFRP-2 (rat) belongs to the RFamide peptides family, called RFamide-related peptides (RFRPs), which exist in the mammalian brain. Synonyms: Neuropeptide VF Precursor (108-125) amide (rat); H-Ala-Asn-Met-Glu-Ala-Gly-Thr-Met-Ser-His-Phe-Pro-Ser-Leu-Pro-Gln-Arg-Phe-NH2; L-alanyl-L-asparagyl-L-methionyl-L-alpha-glutamyl-L-alanyl-glycyl-L-threonyl-L-methionyl-L-seryl-L-histidyl-L-phenylalanyl-L-prolyl-L-seryl-L-leucyl-L-prolyl-L-glutaminyl-L-arginyl-L-phenylalaninamide; RFamide-Related Peptide 2 (rat). Grade: 95%. CAS No. 420088-80-8. Molecular formula: C88H134N26O25S2. Mole weight: 2020.29. | |
| RFRP 3 (human) | RFRP-3 (RFamide-related peptide-3), a homolog of avian gonadotropin-inhibitory hormone, is an agonist of the NPFF1 receptor (IC50 = 0.7 nM for inhibition of forskolin-induced cAMP production). The human RFRP-3 was recently shown to potently inhibit GnRH stimulation of gonadotropin secretion from sheep in vivo and from cultured gonadotropes through inhibition of Ca2+ mobilization. Synonyms: NPVF; Neuropeptide VF (124-131) (human); H-Val-Pro-Asn-Leu-Pro-Gln-Arg-Phe-NH2; L-valyl-L-prolyl-L-asparagyl-L-leucyl-L-prolyl-L-glutaminyl-L-arginyl-L-phenylalaninamide; Neuropeptide NPVF; RFamide-related peptide 3; L-Val-L-Pro-L-Asn-L-Leu-L-Pro-L-Gln-L-Arg-L-Phe-NH2. Grade: ≥95% by HPLC. CAS No. 311309-27-0. Molecular formula: C45H72N14O10. Mole weight: 969.15. | |
| RFRP3 (human) acetate | RFRP3 (human) acetate, a homolog of avian gonadotropin-inhibitory hormone, is an agonist of the NPFF1 receptor (IC50 = 0.7 nM for inhibition of forskolin-induced cAMP production). The human RFRP3 can effectively inhibit GNRH-stimulated gonadotropin secretion in sheep in vivo and in culture by inhibiting Ca2+ mobilization. Synonyms: H-Val-Pro-Asn-Leu-Pro-Gln-Arg-Phe-NH2.CH3CO2H; L-valyl-L-prolyl-L-asparagyl-L-leucyl-L-prolyl-L-glutaminyl-L-arginyl-L-phenylalaninamide acetic acid; RFRP-3 acetate; RFRP 3 acetate; RFamide-related peptide-3 acetate. Grade: ≥95%. Molecular formula: C47H76N14O12. Mole weight: 1029.19. | |
| RGD peptide | RGD peptide is an inhibitor of integrin-ligand interactions. Synonyms: H-Gly-Arg-Gly-Asp-Asn-Pro-OH; RGD peptide (GRGDNP); glycyl-L-arginyl-glycyl-L-alpha-aspartyl-L-asparagyl-L-proline; (S)-1-((6S,12S,15S)-1-amino-15-(2-amino-2-oxoethyl)-6-(2-aminoacetamido)-12-(carboxymethyl)-1-imino-7,10,13-trioxo-2,8,11,14-tetraazahexadecane)pyrrolidine-2-carboxylic acid. Grade: 98%. CAS No. 114681-65-1. Molecular formula: C23H38N10O10. Mole weight: 614.61. | |
| Rhizoxin | Rhizoxin is an antitumor antibiotic produced by Rhizopus sp. No. F-1360. It was highly active against leukemia L1210 and melanoma B16. Synonyms: Antibiotic WF-1360; WF-1360. Grade: >98%. CAS No. 90996-54-6. Molecular formula: C35H47NO9. Mole weight: 625.7. | |
| Rhodamine-PEG-Biotin, MW 1K-5K | Rhodamine-PEG-Biotin, MW 1,000 is a linear biotinylation polyPEG functionalized with fluorescent probe (red) for labeling. The biotin forms strong complex with avidin/streptavidin used for protein labeling or purification. Please contact us for GMP-grade inquiries. | |
| Ribavirin | Ribavirin is a guanosine (ribonucleic) analog used to stop viral RNA synthesis and viral mRNA capping, thus, it is a nucleoside inhibitor. Synonyms: 1-b-D-ribafuranosyl-1H-1,2,4-triazole-3-carboxamide; MegaRibavirin; NSC 163039; Ravanex; Rebetol; Ribamide; Ribamidil; Ribasphere; Ribavarin; Tribavirin; Vilona; Viramid; Virazole; Virizadole; 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-1,2,4-triazole-3-carboxamide. Grade: ≥95%. CAS No. 36791-04-5. Molecular formula: C8H12N4O5. Mole weight: 244.20. | |
| Ribostamycin | Ribostamycin is an antibiotic produced by Streptomyces ribosidifcus. It is active against gram-positive bacteria. Synonyms: Vistamycin; Hetangmycin; Xylostatin; Antibiotic SF 733; SF-733; SF 733. Grade: 95%. CAS No. 25546-65-0. Molecular formula: C17H34N4O10. Mole weight: 454.47. | |
| Ribostamycin sulfate | Ribostamycin is an aminoglycoside antibiotic, containing a neutral sugar moiety, and is produced by Streptomyces ribosidificus. Synonyms: Vistamycin Sulfate; Landamycine; Ribomycine. Grade: >98%. CAS No. 53797-35-6. Molecular formula: C17H36N4O14S. Mole weight: 552.55. | |
| (R)-Ibuprofen-[d3] | (R)-Ibuprofen-[d3] is the labelled analogue of (R)-Ibuprofen, which is a nonsteroidal anti-inflammatory drug (NSAID). Synonyms: (R)-Ibuprofen D3; (R)-(-)-Ibuprofen-d3; (αR)-α-(Methyl-d3)-4-(2-methylpropyl)benzeneacetic Acid; (-)-Ibuprofen-d3; (R)-2-(4-Isobutylphenyl)propanoic Acid-d3; (R)-Ibuprofen-d3; R-(-)-p-Isobutylhydratropic Acid-d3. Grade: ≥98% by HPLC; ≥99% atom D. CAS No. 121702-86-1. Molecular formula: C13H15D3O2. Mole weight: 209.31. | |
| Ridaforolimus | Ridaforolimus is a small molecule and non-prodrug analogue of the lipophilic macrolide antibiotic rapamycin with potential antitumor activity. Ridaforolimus binds to and inhibits the mammalian target of rapamycin (mTOR), which may result in cell cycle arrest and, consequently, the inhibition of tumor cell growth and proliferation. Upregulated in some tumors, mTOR is a serine/threonine kinase involved in regulating cellular proliferation, motility, and survival that is located downstream of the PI3K/Akt signaling pathway. Synonyms: AP23573; AP 23573; AP-23573; MK8669; MK 8669; MK-8669; Deforolimus. Grade: >95% by HPLC. CAS No. 572924-54-0. Molecular formula: C53H84NO14P. Mole weight: 990.20. | |
| Rifampicin | It is a semi-synthetic antibiotic of the rifamycin group. It is an inhibitor of bacterial RNA polymerase and has antibacerial activity. Uses: Antibiotics, antitubercular; enzyme inhibitors; leprostatic agents; nucleic acid synthesis inhibitors. Synonyms: Rimactane; 3-[[(4-Methyl-1-piperazin-yl)imino]methyl]rifamycin; Abrifam; Eremfat; Famcin; NSC 113926; Rifa; Rifacap; Rifadin; Rifadine; Rifaldazine; Rifampicin SV; Rifamycin AMP; Rifaprodin; Rifoldin; Riforal; Rimactan; Rimactane; Rimapen; Sinerdol; Tubocin. Grade: 98%. CAS No. 13292-46-1. Molecular formula: C43H58N4O12. Mole weight: 822.94. | |
| Rifapentine | Rifapentine (Priftin) is a semi-synthetic antibiotic compound used in the treatment of tuberculosis. Synonyms: MDL473; MDL 473; MDL-473; DL 473; DL-473; DL473; R 773; R-773; R773. Grade: >98%. CAS No. 61379-65-5. Molecular formula: C47H64N4O12. Mole weight: 877.03. | |
| Rifaximin EP Impurity B | Rifaximin EP Impurity B is an impurity of Rifaximin. Rifaximin is a semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity. It also acts as a pregnane X receptor (PXR) agonist. It is approved for the treatment of traveler's diarrhea, irritable bowel syndrome, and hepatic encephalopathy. Uses: A rifamycin (r508200) derivative as antibacterial agent. Synonyms: Rifamycin B; Nancimycin; 4-O-(Carboxymethyl)rifamycin; 4-O-(Carboxymethyl)rifamycin; [(1,2-Dihydro-5,6,17,19,21-pentahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,11-dioxo-2,7-(epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-9-yl)oxy]acetic Acid 21-Acetate. CAS No. 13929-35-6. Molecular formula: C39H49NO14. Mole weight: 755.80. | |
| Rifaximin EP Impurity C | Rifaximin EP Impurity C is an antibacterial drug which functions by inhibiting bacterial RNA polymerase (RNAP), is an impurity of Rifaximin. It also has anti-gram-positive bacterial and mycobacterium activities. Uses: Anti-bacterial agents. Synonyms: Rifamycin SV; Rifocin; Rifamicine SV; (2S,12Z,14E,16S,17S,18R,19R,20R,21S,22R,23S,24E)-21-(Acetyloxy)-5,6,9,17,19-pentahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-2,7-(epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-1,11(2H)-dione. Grade: >95%. CAS No. 6998-60-3. Molecular formula: C37H47NO12. Mole weight: 697.77. | |
| Rifaximin EP Impurity E | Rifaximin EP Impurity E is an impurity of Rifaximin. Rifaximin is a semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity. It also acts as a pregnane X receptor (PXR) agonist. It is approved for the treatment of traveler's diarrhea, irritable bowel syndrome, and hepatic encephalopathy. Synonyms: Rifamycin S; 5,17,19,21-Tetrahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-2,7-(epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-1,6,9,11(2H)-tetrone 21-Acetate; 1,4-Dideoxy-1,4-dihydro-1,4-dioxorifamycin. Grade: 98%. CAS No. 13553-79-2. Molecular formula: C37H45NO12. Mole weight: 695.75. | |
| Rifaximin EP Impurity F | Rifaximin EP Impurity F is an intermediate of Rifaximin. Rifaximin is a semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity. It also acts as a pregnane X receptor (PXR) agonist. It is approved for the treatment of traveler's diarrhea, irritable bowel syndrome, and hepatic encephalopathy. Uses: Rifaximin intermediate. Synonyms: Rifamycin O; 4-O-(Carboxymethyl)-1-deoxy-1,4-dihydro-4-hydroxy-1-oxo-rifamycin γ-Lactone. Grade: 95%. CAS No. 14487-05-9. Molecular formula: C39H47NO14. Mole weight: 753.79. | |
| Rilmenidine | Rilmenidine, an innovative antihypertensive agent, is an orally active, selective I1 imidazoline receptor agonist. Rilmenidine is an alpha 2-adrenoceptor agonist. Rilmenidine induces autophagy. Rilmenidine modulates proliferation and stimulates the proapoptotic protein Bax thus inducing the perturbation of the mitochondrial pathway and apoptosis in human leukemic K562 cells[1][2][3]. Uses: Adrenergic alpha-2 receptor agonists. Synonyms: Rilmenidine; 54187-04-1; Oxaminozoline; Hyperium; N-(Dicyclopropylmethyl)-4,5-dihydrooxazol-2-amine; Rilmenidine [INN]; N-(Dicyclopropylmethyl)-4,5-dihydro-1,3-oxazol-2-amine; Rilmenidia [Spanish]; Rilmenidinum [Latin]; 2-Oxazolamine, N-(dicyclopropylmethyl)-4,5-dihydro-; CHEBI:8862; Oxazolidine, 2-((dicyclopropylmethyl)imino)-; N-(dicyclopropylmethyl)-4,5-dihydrooxazol-3-ium-2-amine; N-(Dicyclopropylmethyl)-N-(4,5-dihydro-1,3-oxazol-2-yl)amine. Grade: > 95%. CAS No. 54187-04-1. Molecular formula: C10H16N2O. Mole weight: 180.25. | |
| Rilmenidine-[d4] | An isotope labelled Rilmenidine. Rilmenidine is a medication for the treatment of hypertension. Synonyms: N-(dicyclopropylmethyl)-4,5-dihydro(D4)-1,3-oxazol-2-amine. Grade: 95% by HPLC; 98% atom D. CAS No. 85047-14-9. Molecular formula: C10H12D4N2O. Mole weight: 184.28. | |
| Rilmenidine fumarate | Rilmenidine fumarate. CAS No. 54249-57-9. | |
| Rilmenidine hemifumarate | Rilmenidine hemifumarate, a centrally acting antihypertensive agent, is an I1-imidazoline binding site selective ligand and α2-adrenoceptor agonist. Rilmenidine targets the nonadrenergic imidazoline-binding site I1 receptor with a Ki value of 7.1 nM and demonstrates weaker affinity for the I2 receptor with a Ki value of 5.2 μM. Synonyms: 2-[N-(Dicyclopropylmethyl)amino]oxazoline hemifumarate; Oxaminozoline; S 3341. Grade: ≥99% by HPLC. CAS No. 207572-68-7. Molecular formula: C10H16N2O.1/2C4H4O4. Mole weight: 238.29. | |
| Rilmenidine Impurity A | Rilmenidine Impurity A. Synonyms: Rilmenidine Impurity A; 54187-44-9; N-(Dicyclopropylmethyl)-N'-(2-hydroxyethyl)urea; 1-(DICYCLOPROPYLMETHYL)-3-(2-HYDROXYETHYL)UREA; starbld0007487; SCHEMBL11637079; BCP25666; N-(Dicyclopropylmethyl)-N inverted exclamation mark -(2-hydroxyethyl)urea. Grade: > 95%. CAS No. 54187-44-9. Molecular formula: C10H18N2O2. Mole weight: 198.27. | |
| Rilmenidine Impurity B | An impurity of Rilmenidine,Rilmenidine Is A novel non-nucleoside reverse transcriptase inhibitor. Rilpivirine seems to be well tolerated with less CNS disturbance than Efavirenz, and has non-teratogenic potential. An anti-HIV agent. Synonyms: 1-(2-chloroethyl)-3-(dicyclopropylmethyl)urea. Grade: > 95%. Molecular formula: C10H17ClN2O. Mole weight: 216.71. | |
| Rilmenidine Impurity C | An impurity of Rilmenidine,Rilmenidine Is A novel non-nucleoside reverse transcriptase inhibitor. Rilpivirine seems to be well tolerated with less CNS disturbance than Efavirenz, and has non-teratogenic potential. An anti-HIV agent. Synonyms: 2-[N-(Dicyclopropylmethyl)imino]-N-(dicyclopropylmethyl)isooxazoline Synonyms: 1,1-Dicyclopropyl-N-(3-(dicyclopropylmethyl)oxazolidin-2-ylidene)methanamine. Grade: > 95%. Molecular formula: C17H26N2O. Mole weight: 274.41. | |
| Rilmenidine Phosphate | Rilmenidine Phosphate is a selective I(1) imidazoline receptor agonist, used for the treatment of hypertension. Synonyms: S 3341-3; N-(Dicyclopropylmethyl)-4,5-dihydro-2-oxazolamine Phosphate. Grade: 98%. CAS No. 85409-38-7. Molecular formula: C10H19N2O5P. Mole weight: 278.24. | |
| Ristocetin A | Ristocetin A is a potent antibacterial glycopeptide antibiotic. It induced platelet aggregation by binding to a factor absent in people suffering from von willebrands disease, and is an important diagnostic acid. Synonyms: Ristomycin A; 1H,15H,34H-20,23:30,33-Dietheno-3,18:35,48-bis(iminomethano)-4,8:10,14:25,28:43,47-tetrametheno-28H-[1,14,6,22]dioxadiazacyclooctacosino[4,5-m][10,2,16]benzoxadiazacyclotetracosine, ristomycin A deriv. Grade: >95% by HPLC. CAS No. 11021-66-2. Molecular formula: C95H110N8O44. Mole weight: 2067.92. | |
| Ristocetin A sulfate | It is a class III antibiotic isolated from Amycolatopsis lurida originally used in the treatment staphylococcal infections. However, it has side effects like thrombocytopenia and platelet agglutination. Synonyms: Ristomycin III; Ristomycin A Monosulfate. Grade: ≥95%. CAS No. 90831-71-3. Molecular formula: C95H112N8O48S. Mole weight: 2166.00. | |
| Ristocetin sulfate | Ristocetin sulfate is a potent antibacterial glycopeptide antibiotic produced by Amycolatopsis lurida, which was withdrawn from clinical use following a high incidence of thrombocytopenia. Synonyms: Ristomycin sulfate; Ristomycin monosulfate. Grade: >95% by HPLC. CAS No. 11140-99-1. | |
| Risuteganib | ALG1001, also known as Luminate, a first-in-class integrin peptide therapy, is an angiogenesis inhibitors and Integrin alpha 5 beta 1 modulator. A study from Johns Hopkins University also showed that ALG-1001 reduced vascular leakage. Synonyms: ALG 1001; ALG1001; ALG-1001; H-Gly-Arg-Gly-Cys(O3H)-Thr-Pro-OH; Gly-Arg-Gly-Cys(acid)-Thr-Pro; glycyl-L-arginyl-glycyl-L-cysteyl-L-threonyl-L-proline. CAS No. 1307293-62-4. Molecular formula: C22H39N9O11S. Mole weight: 637.66. | |
| (R)-Linezolid-[d3] | (R)-Linezolid-[d3] is the labelled analogue of (R)-Linezolid, which is an enatiomeric impurity of Linezolid. Synonyms: (R)-Linezolid-d3; N-[[(5R)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide-d3. Grade: >95%. CAS No. 1795786-02-5. Molecular formula: C16H17D3FN3O4. Mole weight: 340.36. | |
| RLLFT-NH | RLLFT-NH is a reversed amino acid sequence control peptide for TFLLR-NH2. TFLLR-NH2 is a peptide derived from the protease-activated receptor-1 (PAR1) that acts as a PAR1 selective agonist (EC50 = 1.9 μM). Synonyms: RLLFT. CAS No. 447408-68-6. Molecular formula: C31H53N9O6. Mole weight: 647.82. | |
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