BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| PKG Substrate | PKG Substrate is a selective substrate for cGMP-dependent protein kinase (PKG). Synonyms: Arg-Lys-Arg-Ser-Arg-Ala-Glu; L-arginyl-L-lysyl-L-arginyl-L-seryl-L-arginyl-L-alanyl-L-glutamic acid; N5-(Diaminomethylidene)-L-ornithyl-L-lysyl-N5-(diaminomethylidene)-L-ornithyl-L-seryl-N5-(diaminomethylidene)-L-ornithyl-L-alanyl-L-glutamic acid; (S)-2-((6S,9S,12S,15S,18S,21S)-1,6-diamino-9-(4-aminobutyl)-12,18-bis(3-guanidinopropyl)-15-(hydroxymethyl)-1-imino-21-methyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosanamido)pentanedioic acid. Grade: ≥95%. CAS No. 81187-14-6. Molecular formula: C35H67N17O11. Mole weight: 902.01. |  |
| PKI 14-22 amide, myristoylated | PKI 14-22 amide, myristoylated is a cell-permeable version of protein kinase inhibitor PKI (14-22) amide. N-terminus is myristoylated to increase cell membrane permeability. The non-myristoylated version of this peptide is a highly specific inhibitor of cAMP-dependent protein kinase (PKA) with Ki=36 nM. This product is a useful tool for studying PKA in cellular systems. Synonyms: Protein kinase inhibitor-(14-22)-amide, myristoylated. Grade: >98%. CAS No. 201422-03-9. Molecular formula: C53H100N20O12. Mole weight: 1209.5. | |
| PKI (5-24) | PKI (5-24) is a competitive, non-reversible peptide inhibitor of PKA (cAMP-dependent protein kinase) (Ki = 2.3 nM). Its sequence is derived from the heat-stable skeletal muscle inhibitor protein of PKA. The PKA Inhibitor peptide binds to the catalytic subunit of PKA and displaces the regulatory subunit, and mimics protein substrate by binding to the catalytic site via the Arg-cluster basic residues. Synonyms: L-threonyl-L-threonyl-L-tyrosyl-L-alanyl-L-a-aspartyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-serylglycyl-L-arginyl-L-threonylglycyl-larginyl-L-aspartic acid; PKI (5-24); Protein Kinase A Inhibitor (5-24). CAS No. 99534-03-9. Molecular formula: C94H148N32O31. Mole weight: 2222.4. | |
| PKI (5-24) acetate | PKI (5-24) acetate is a competitive, non-reversible peptide inhibitor of PKA (cAMP-dependent protein kinase) (Ki = 2.3 nM). Synonyms: H-Thr-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-His-Asp-OH.CH3CO2H; L-Threonyl-L-threonyl-L-tyrosyl-L-alanyl-L-α-aspartyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-serylglycyl-L-arginyl-L-threonylglycyl-L-arginyl-L-arginyl-L-asparaginyl-L-alanyl-L-isoleucyl-L-histidyl-L-aspartic acid acetate salt; PKI(5-24) acetate salt. Grade: ≥95%. Molecular formula: C96H152N32O33. Mole weight: 2282.43. | |
| Platencin | Platencin is a broad-spectrum Gram-positive antibiotic produced by Streptomyces. Platencin is an effective antibiotic against FabF and FabH proteins. No toxicity was observed. Grade: >99% by HPLC. CAS No. 869898-86-2. Molecular formula: C24H27NO6. Mole weight: 425.47. | |
| Platensimycin | Platensimycin is a broad spectrum, gram-positive antibiotic produced by strains of streptomyces platensis. It inhibits bacterial growth by selectively inhibiting the elongation enzyme, b-ketoacyl acyl carrier protein synthase (fabf) of the fatty acid synthesis pathway. Synonyms: (-)-Platensimycin. Grade: >95% by HPLC. CAS No. 835876-32-9. Molecular formula: C24H27NO7. Mole weight: 441.47. | |
| Plecanatide | Plecanatide, also called Trulance, a synthetic analogue of uroguanylin, is a guanylate cyclase-C (GCC) agonist being developed by Synergy Pharmaceuticals for the treatment of gastrointestinal disorders, such as chronic idiopathic constipation (CIC) and irritable bowel syndrome with constipation (IBS-C). In January 2017, an oral formulation of plecanatide received its first global approval in the USA for the treatment of adult patients with CIC. Besides, Plecanatide is undergoing phase III investigation in IBS-C. It had also undergone preclinical investigations in inflammatory bowel disease (IBD) and ulcerative colitis; however, development in these indications has been discontinued. Uses: Guanylyl cyclase c agonists; gastrointestinal agents. Synonyms: L-Leucine, L-asparaginyl-L-α-aspartyl-L-α-glutamyl-L-cysteinyl-L-α-glutamyl-L-leucyl-L-cysteinyl-L-valyl-L-asparaginyl-L-valyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-, cyclic (4→12)?,?(7→15)?-bis(disulfide); 105: PN: WO2012037380 SEQID: 105 claimed protein; 1: PN: US20100152118 SEQID: 1 claimed protein; 1: PN: WO2008151257 SEQID: 1 claimed protein; 1: PN. CAS No. 467426-54-6. Molecular formula: C65H104N18O26S4. Mole weight: 1681.89. | |
| Pleuromutilin | It is produced by the strain of Drosophila subatrata. It is mainly anti-gram-positive bacterial activity. Synonyms: Drosophilin B; Drosopholin B; Mutilin 14-glycolate; (3aR,4R,5R,7S,8S,9R,9aS,12R)-8-hydroxy-4,7,9,12-tetramethyl-3-oxo-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulen-5-yl 2-hydroxyacetate; Valnemulin impurity E; Glycolic acid, 8-dihydroxy-4,6,9,10-tetramethyl-6-vinyl-3a,9-propano-3aH-cyclopentacycloocten-1(4H)-one; antibiotic bc757. Grade: >95%. CAS No. 125-65-5. Molecular formula: C22H34O5. Mole weight: 378.50. | |
| Plitidepsin | Plitidepsin is a cyclic depsipeptide isolated from the marine tunicate Aplidium albicans. Plitidepsin shows potent anticancer activity against a large variety of cultured human cancer cells, inducing apoptosis by triggering mitochondrial cytochrome c release, initiating the Fas/DC95, JNK pathway and activating caspase 3 activation. This agent also inhibits elongation factor 1-a, thereby interfering with protein synthesis, and induces G1 arrest and G2 blockade, thereby inhibiting tumor cell growth. Synonyms: aplidin; aplidine; plitidepsin; dehydrodidemnin B. Grade: >98%. CAS No. 137219-37-5. Molecular formula: C57H87N7O15. Mole weight: 1110.34. | |
| PLL-g-PEG-Biotin | PLL-g-PEG-Biotin is a biotinylated poly-L-lysine PEG conjugate that was made from the covalent attachment of PEG 2000 and biotin to the Poly-L-lysine molecules. It is a positively charged PLL-g-PEG copolymer that can bind to streptavidin or avidin with high affinity. It is a linear amphiphilic block copolymer used for gene transfection or surface modification. Synonyms: Poly(L-lysine)-graft-biotinylated PEG; Biotinylated PLL-g-PEG; Poly lysine-g-polyethylene glycol-biotin. | |
| PLP 139-151 | PLP 139-151 is the 139-151 amino acid residue of myelin protein (PLP), used to induce experimental autoimmune encephalomyelitis (EAE). Synonyms: Myelin Proteolipid Protein (139-151) (depalmitoylated) (human, bovine, dog, mouse, rat); His-Cys-Leu-Gly-Lys-Trp-Leu-Gly-His-Pro-Asp-Lys-Phe; L-histidyl-L-cysteinyl-L-leucyl-glycyl-L-lysyl-L-tryptophyl-L-leucyl-glycyl-L-histidyl-L-prolyl-L-alpha-aspartyl-L-lysyl-L-phenylalanine. Grade: >98%. CAS No. 131334-43-5. Molecular formula: C72H104N20O16S. Mole weight: 1537.79. | |
| PM 102 | PM 102, an antagonist of heparin, is a peptide that reverses the anticoagulant effect of heparin. Synonyms: PM 102; PM102; PM-102; AEARARRAAARAARRAKK(AEARARRAAARAARRA)PX(AEARARRAAARAARRA)EN. CAS No. 1234564-95-4. Molecular formula: C235H425N111O64. Mole weight: 5830. | |
| p-Methylbenzyl benzoate | p-Methylbenzyl benzoate. CAS No. 38418-10-9. Molecular formula: C15H14O2. Mole weight: 226.27. | |
| PMSF | Used as a Protease inhibitor such as Chymotrypsin, Trypsin and Thrombin as well as Acetylcholineesterase. Synonyms: Phenylmethylsulfonyl Fluoride. Grade: ≥ 99% (GC). CAS No. 329-98-6. Molecular formula: C7H7FO2S. Mole weight: 174.19. | |
| PMX 205 | PMX 205 is a potent C5a receptor peptide antagonist (IC50 = 31 nM). It is orally active and blocks inflammatory signaling and symptoms in animal models of colitis and allergic asthma. PMX 205 reduces fibrillar amyloid deposits, decreases hyperphosphorylated tau levels and rescues cognitive function in a mouse model of Alzheimer's Disease. Synonyms: PMX-205; Hydrocinnamate. Grade: >98%. CAS No. 514814-49-4. Molecular formula: C45H62N10O6. Mole weight: 839.05. | |
| PMX 205 acetate | PMX 205 acetate is a potent complement C5a receptor antagonist (IC50 = 31 nM). It is orally active and blocks inflammatory signaling and symptoms in animal models of colitis and allergic asthma. PMX 205 reduces fibrillar amyloid deposits, decreases hyperphosphorylated tau levels and rescues cognitive function in a mouse model of Alzheimer's Disease. Synonyms: hydrocinnamoyl-Orn(1)-Pro-D-Cha-Trp-Arg-(1).CH3CO2H; L-Arginine, N2-(1-oxo-3-phenylpropyl)-L-ornithyl-L-prolyl-3-cyclohexyl-D-alanyl-L-tryptophyl-, (5→1)-lactam acetate; PMX205 acetate; PMX-205 acetate; Hydrocinnamate-(Orn-Pro-DCHA-Trp-Arg) acetate. Grade: ≥95%. Molecular formula: C47H66N10O8. Mole weight: 899.09. | |
| PMX 53 | PMX 53 is a dual C5aR(CD88) antagonist and Mas-related gene 2 (MrgX2) agonist. It stimulates MrgX2-mediated mast cell degranulation, and also inhibits C5a-induced hypernociception in rats, inhibits lung metastasis in a mouse breast cancer model and reduces atherosclerotic lesions in a mouse model of atherosclerosis. Synonyms: L-Arginine, N-acetyl-L-phenylalanyl-L-ornithyl-L-prolyl-3-cyclohexyl-D-alanyl-L-tryptophyl-, (6→2)-lactam; 3D53; C 5aRA; PMX53; PMX-53; Ac-Phe-Orn(1)-Pro-D-Cha-Trp-Arg-(1); Ac-Phe-cyclo(Orn-Pro-D-Cha-Trp-Arg); Ac-Phe-[Orn-Pro-cha-Trp-Arg]. Grade: >98%. CAS No. 219639-75-5. Molecular formula: C47H65N11O7. Mole weight: 896.09. | |
| PMX 53 acetate | PMX 53 is a potent and orally active C5aR(CD88) antagonist and Mas-related gene 2 (MrgX2) agonist. It stimulates MrgX2-mediated mast cell degranulation, inhibits C5a-induced neutrophil myeloperoxidase release and chemotaxis, inhibits lung metastasis in a mouse breast cancer model, and reduces atherosclerotic lesions in a mouse model of atherosclerosis. Synonyms: L-Arginine, N-acetyl-L-phenylalanyl-L-ornithyl-L-prolyl-3-cyclohexyl-D-alanyl-L-tryptophyl-, (6→2)-lactam, monoacetate; Ac-Phe-Orn(1)-Pro-D-Cha-Trp-Arg-(1).CH3CO2H; C 5aRA acetate salt. Grade: ≥95%. CAS No. 852629-88-0. Molecular formula: C47H65N11O7.C2H4O2. Mole weight: 956.14. | |
| PMX 53 TFA | PMX 53 is a dual C5aR (CD88) antagonist and Mas-related gene 2 (MrgX2) agonist. It stimulates MrgX2-mediated mast cell degranulation, and also inhibits C5a-induced hypernociception in rats, inhibits lung metastasis in a mouse breast cancer model and reduces atherosclerotic lesions in a mouse model of atherosclerosis. Synonyms: L-Arginine, N-acetyl-L-phenylalanyl-L-ornithyl-L-prolyl-3-cyclohexyl-D-alanyl-L-tryptophyl-, (6→2)-lactam, mono(trifluoroacetate); PMX53 TFA; PMX-53 TFA; PMX 53 Trifluoroacetate; PMX53 Trifluoroacetate; PMX-53 Trifluoroacetate. Grade: ≥95%. CAS No. 852629-87-9. Molecular formula: C49H66F3N11O9. Mole weight: 1010.11. | |
| Pneumocandin A0 | Pneumocandin A0 is a lipopeptide antibiotic produced by Zalerion arboricola. It has a strong anti-Candida effect. It has the effect of inhibiting the synthesis of 1,3 early-glucan in vitro, with an IC50 of 0.07-0.5 μg/mL. Pneumocandin A0 is an impurity of Micafungin. Synonyms: 1H-Dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacycloheneicosine, cyclic peptide deriv.; Antibiotic L 671329; L 671329; Stereoisomer of N2-(10,12-dimethyl-1-oxotetradecyl)-4,5-dihydroxy-L-ornithyl-L-threonyl-4-hydroxy-L-prolyl-4-hydroxy-4-(4-hydroxyphenyl)-L-threonyl-3-hydroxy-L-glutaminyl-3-hydroxy-4-methyl-L-proline cyclic (6→1)-peptide. Grade: 95%. CAS No. 120692-19-5. Molecular formula: C51H82N8O17. Mole weight: 1079.24. | |
| Pneumocandin B0 | Pneumocandin B0 is a lipopeptide antibiotic produced by Zalerion arboricola. It has a strong anti-Candida effect. It has the effect of inhibiting the synthesis of 1,3 early-glucan in vitro, with an IC50 of 0.07-0.5 μg/mL. Uses: Antifungal. Synonyms: L-688,786; L 688,786; L688,786; L-688786; L 688786; L688786; (3S)-(4R,5R)-N2-[(10R,12S)-10,12-Dimethyl-1-oxotetradecyl]- 4,5-dihydroxy-L-ornithyl-L-threonyl-(4R)-4-hydroxy-L-prolyl-(4S)-4-hydroxy-4-(4-hydroxyphenyl)-L-threonyl-(3R)-3-hydroxy-L-glutaminyl-3-hydroxy-L-proline (6→1)-Lactam. Grade: >98%. CAS No. 135575-42-7. Molecular formula: C50H80N8O17. Mole weight: 1065.21. | |
| Pneumocandin C0 | Pneumocandin C0 is a lipopeptide antibiotic produced by Zalerion arboricola. It has a strong anti-Candida effect. It has the effect of inhibiting the synthesis of 1,3 early-glucan in vitro, with an IC50 of 0.07-0.5 μg/mL. Pneumocandin C0 is an impurity of Caspofungin acetate which is an essential component of the cell wall of filamentous fungi. Synonyms: Pneumocandin B0, 6-(trans-4-hydroxy-L-proline)-; Pneumocandin B0, 6-((4R)-4-hydroxy-L-proline)-; 6-[(4R)-4-Hydroxy-L-proline]pneumocandin B0. Grade: ≥95%. CAS No. 144074-96-4. Molecular formula: C50H80N8O17. Mole weight: 1065.21. | |
| PNU-159682 | PNU-159682 is a major active metabolite of nemorubicin (MMDX) in human liver microsomes. It is a highly potent DNA topoisomerase II inhibitor with excellent cytotoxicity, and shows >3,000-fold cytotoxic than its parent compound (MMDX and doxorubicin). It is a more potent and well tolerated ADC cytotoxin than doxorubicin. Uses: Adcs cytotoxin. Synonyms: (8S,10S)-7,8,9,10-Tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-(((1S,3R,4aS,9S,9aR,10aS)-octahydro-9-methoxy-1-methyl-1H-pyrano(4',3':4,5)oxazolo(2,3-c)(1,4)oxazin-3-yl)oxy)-5,12-naphthacenedione; 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-(((1S,3R,4aS,9S,9aR,10aS)-octahydro-9-methoxy-1-methyl-1H-pyrano(4',3':4,5)oxazolo(2,3-c)(1,4)oxazin-3-yl)oxy)-, (8S,10S)-; PNU159682; PNU 159682. Grade: ≥97%. CAS No. 202350-68-3. Molecular formula: C32H35NO13. Mole weight: 641.62. | |
| Polyaniline (emeraldine salt) long chain, grafted to lignin | Polyaniline (emeraldine salt) long chain, grafted to lignin. CAS No. 335349-50-3. | |
| Polyaniline (emeraldine salt) short chain, grafted to lignin | Additive in polymer blends and liquid dispersions for corrosion resistant coatings; antistatic fabrics, coatings, and packaging; conductive inks and adhesives; printed circuit boards; radar and microwave absorption; EMI/RFI shielding; sensors. PANI-LIG can be used in a variety of applications such as energy harvesting, dye sensitized solar cells, biosensors, and synthesis of ruthenium nanoparticles. Synonyms: Lignosulfonic acid, ethoxylated, compds. with polyaniline, hydrochlorides. CAS No. 313949-90-5. | |
| Poly(Bisphenol A carbonate) | Poly(Bisphenol A carbonate). Synonyms: Bisphenol-A-polycarbonate; 25037-45-0; Carbonicacid,polyesterwith4,4'-isopropylidenediphenol; carbonicacid-4,4'-propane-2,2-diyldiphenol(1:1); Carbonicacid,polymerwith4,4'-(1-methylethylidene)bis(phenol); BisphenolAcarbonate. Grade: 95%. CAS No. 25037-45-0. Molecular formula: C16H18O5. Mole weight: 290.31112. | |
| Polybutylated bisphenol A | Polybutylated bisphenol A. CAS No. 68784-69-0. Molecular formula: C15H16O2·C8H8·C4H8. Mole weight: 388.50. | |
| Polyester bis-MPA dendron 2 carboxyl, 1 biotin (core) | Polyester bis-MPA dendron 2 carboxyl, 1 biotin (core) stands as an incredibly versatile substance widely employed in the realm of biomedicine. Possessing a paramount core structure, it garners extensive utilization within the domain of drug delivery systems. Manifesting exceptional attributes conducive to the targeting of distinct ailments, drug conveyance, and proficient release at designated loci, this product proves instrumental in combatting an array of maladies encompassing cancers, infections, and neurological disorders. Molecular formula: C31H48N2O16S. Mole weight: 736.78. | |
| Polyester bis-MPA dendron 2 NHBoc, 1 Biotin (core) | Polyester bis-MPA dendron 2 NHBoc, 1 Biotin (core) is a biomedical product used in the drug development of certain diseases. This product acts as a carrier system for targeted drug delivery due to its unique properties. It can effectively encapsulate and transport drugs, such as anti-cancer agents or antibiotics, to specific sites in the body. Additionally, the presence of biotin allows for the attachment of targeting moieties, enhancing drug specificity and efficacy. Molecular formula: C39H66N4O16S. Mole weight: 879.02. | |
| Polyester bis-MPA dendron 4 carboxyl, 1 biotin (core) | Polyester bis-MPA dendron 4 carboxyl, biotin (core) presents a versatile groundwork for the nuanced realm of targeted drug delivery. Through the strategic attachment of biotin to its core structure, an array of possibilities manifests, encompassing the potential to combat malignant neoplasms and diverse autoimmune maladies. Molecular formula: C49H72N2O28S. Mole weight: 1169.16. | |
| Polyester bis-MPA dendron 4 NHBoc, 1 Biotin (core) | Polyester bis-MPA dendron 4 NHBoc, 1 Biotin (core) is designed for targeted drug delivery. Its core, consisting of Biotin, allows for specific binding to targeted cells or receptors. This facilitates the delivery of drugs for the treatment of various diseases, enhancing therapeutic efficacy and reducing side effects. Its unique structure, incorporating Polyester bis-MPA dendron with NHBoc, further improves drug encapsulation and stability. Molecular formula: C65H108N6O28S. Mole weight: 1453.64. | |
| Polyester bis-MPA dendron 8 carboxyl, 1 biotin (core) | Polyester bis-MPA dendron 8 carboxyl, 1 biotin (core) is a specialized biomedical product utilized in drug delivery systems. This versatile dendron-based polyester offers excellent biocompatibility and controlled release properties. It is commonly employed in targeted therapies for diseases such as cancer, where it efficiently transports anticancer drugs to tumor cells. Its core, comprising 1 biotin, facilitates selective targeting and uptake by biotin receptor overexpressing cells. Molecular formula: C85H120N2O52S. Mole weight: 2033.91. | |
| Polyester bis-MPA dendron 8 NHBoc, 1 Biotin (core) | Polyester bis-MPA dendron 8 NHBoc, 1 Biotin (core) is a biomedicine compound meticulously engineered for the purpose of precision drug delivery systems and cutting-edge imaging applications. By virtue of its biotin core and intricately structured polyester bis-MPA dendron 8 NHBoc configuration, this revolutionary creation facilitates targeted therapeutic interventions through specific biomolecular interactions. With its promise to revolutionize the treatment landscape for ailments necessitating tailored approaches like neoplastic afflictions or immune dysregulation, this product embodies unparalleled potential. Molecular formula: C117H192N10O52S. Mole weight: 2602.88. | |
| Polyethyleneglycol Bisphenol A Epichlorohydrin Copolymer | Polyethyleneglycol Bisphenol A Epichlorohydrin Copolymer has been shown to protect the intestinal epithelium against microbial invasion during stress. CAS No. 37225-26-6. | |
| Polyethylene glycol loxenatide | Polyethylene glycol loxenatide is a long-acting glucagon-like peptide-1 receptor agonist for type 2 diabetes mellitus (T2DM). Synonyms: PEX168. | |
| POLYETHYLENIMINE BRANCHED PERMETHYLATED PERMETHOBROMIDE | POLYETHYLENIMINE BRANCHED PERMETHYLATED PERMETHOBROMIDE. Synonyms: POLYETHYLENIMINE BRANCHED PERMETHYLATED PERMETHOBROMIDE. CAS No. 28728-59-8. | |
| Poly(I:C) Biotin | Poly(I:C) Biotin is chemically labeled by covalent coupling of biotin probes containing reactive alkylating groups. Poly(I:C) Biotin has fluorescence characteristics while retaining TLR3 recognition characteristics. Poly(I:C) is a synthetic double-stranded RNA (dsRNA) analog associated with viral infection. Synonyms: Biotin-labeled synthetic analog of dsRNA; Biotin-labeled poly(I:C); Biotinylated poly I:C; Biotin-labeled polyinosine-polycytidylic acid. | |
| Poly(melamine-co-formaldehyde) methylated/butylated (55/45) | Poly(melamine-co-formaldehyde) methylated/butylated (55/45). Grade: 95%. CAS No. 68036-97-5. Molecular formula: C4H8N6O. Mole weight: 156.14600. | |
| Polymyxin B1 | Polymyxin B1 is a cyclic peptide antibiotic of Bacillus polymyxa. The effect of anti-gram-negative bacteria is greater than that of anti-gram-positive bacteria. Synonyms: 4,10-anhydro{N-[(6R)-6-methyloctanoyl]-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-phenylalanyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine}; polymycin B. Grade: ≥95%. CAS No. 4135-11-9. Molecular formula: C56H98N16O13. Mole weight: 1203.47. | |
| Polymyxin B1 Sulfate | It is produced by the strain of Pseudomonas sp. It is one of the polypeptide fractions in polymyxin B sulfate. Polymyxin B1 is an antibacterial compound. It has a high volume of distribution and longer elimination half-life in patients with multidrug-resistant gram-negative bacterial infection. Synonyms: Polymyxin B1 sulfate salt (1:1); N2-(6-Methyl-1-oxooctyl)-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-phenylalanyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine Cyclic (10→4)-Peptide sulfate (1:1). Grade: >90.0%. CAS No. 108965-61-3. Molecular formula: C56H98N16O13.H2SO4. Mole weight: 1301.55. | |
| Polymyxin B3 | Polymyxin B3 is a peptide antibiotic produced by Bacillus polymyxa. Polymyxin B3 is active against gram-negative bacteria. Grade: ≥95%. CAS No. 71140-58-4. Molecular formula: C55H96N16O13. Mole weight: 1189.5. | |
| Polymyxin B3 sulfate | It is produced by the strain of Pseudomonas sp. Polymyxin B3 sulfate is an individual fraction found in the antibiotic mixture polymyxin B sulfate. Polymyxin B targets and alters permeability lipopolysaccharide (LPS) of gram-negative bacteria leading to lysing of the cell. Grade: ≥90.0% by HPLC. Molecular formula: C55H96N16O13.xH2O4S. Mole weight: 1189.45 (free base). | |
| Polymyxin B6 sulfate | It is produced by the strain of Bacillus Polymyxa. Polymyxin B sulfate is a polypeptide antibiotic and is composed of polymyxins B1, B2, and B3 with fractions B1 and B2 comprising the majority of the mixture. Polymyxin B targets and alters permeability lipopolysaccharide (LPS) of gram-negative bacteria leading to lysing of the cell. Grade: >90.0%. Molecular formula: C56H98N16O14.xH2SO4. Mole weight: 1219.47 (free base). | |
| Polymyxin B nonapeptide | Polymyxin B nonapeptide interacts with the outer membrane of gram-negative bacteria to increase the permeability of the membrane by promoting hydrophobic diffusion. Synonyms: Polymyxin B Cyclononapeptide; Polymyxin B1, 1-De(N2-(6-Methyl-1-Oxooctyl)-L-2,4-Diaminobutanoic Acid)-; PMBN; T-Dab-Dab-Dab-Dab-d-FL-Dab-Dab-T (Lactam: Dab3-Thr9); N2-(L-Thr-L-A2bu-)Cyclo(L-A2bu*-L-A2bu-D-Phe-L-Leu-L-A2bu-L-A2bu-L-Thr-); Nα-(L-Thr-L-A2bu-)Cyclo(L-A2bu*-L-A2bu-D-Phe-L-Leu-L-A2bu-L-A2bu-L-Thr-). Grade: ≥95%. CAS No. 86408-36-8. Molecular formula: C43H74N14O11. Mole weight: 963.13. | |
| Polymyxin B sulphate | Polymyxin B is an antibiotic produced by Bacillus polymyxia strains. It is effective against gram-negative infections. Synonyms: Aerosporin; PMB; Poly-RX. CAS No. 1405-20-5. Molecular formula: C56H100N16O17S. Mole weight: 1301.56. | |
| Polymyxin E1 Sulfate | It is produced by the strain of Bacillus polymyxa var. colistinus. Polymyxin E1 Sulfate is sulfate salt form of Polymyxin E1, which is used as an antibiotic in the treatment of infectious diseases resulting from multi-drug resistant (MDR) gram-negative bacteria. Synonyms: Colistin A Sulfate; Polymixin E1 Sulfate salt; Colistin IV Sulfate; N2-(6-Methyl-1-oxooctyl)-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-leucyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine Cyclic (10→4)-Peptide Sulfate. Grade: ≥90.0% by HPLC. Molecular formula: C53H100N16O13.xH2SO4. Mole weight: 1169.46 (free base). | |
| Polymyxin E2 Sulfate | It is produced by the strain of Bacillus polymyxa var. colistinus. Polymyxin E2 Sulfate is sulfate salt form of Polymyxin E2, which is used as an antibiotic in the treatment of infectious diseases resulting from multi-drug resistant (MDR) gram-negative bacteria. Synonyms: Colistin B Sulfate Salt; Polymyxin E2 Sulfate Salt; 1-[(2S)-4-Amino-2-[(6-methyl-1-oxoheptyl)amino]butanoic acid]polymyxin E1 Sulfate Salt; Colistin I Sulfate Salt; N2-(6-Methyl-1-oxoheptyl)-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-leucyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine (10→4)-Lactam Sulfate Salt. Grade: ≥90.0% by HPLC. CAS No. 1338055-88-1. Molecular formula: C52H98N16O13.xH2SO4. Mole weight: 1155.43 (free base). | |
| Polymyxin Ile-B1 Sulfate | It is produced by the strain of Pseudomonas Sp. It is one of the individual polypeptide components in polymyxin B sulfate. Polymyxin B targets and alters permeability lipopolysaccharide (LPS) of gram-negative bacteria leading to lysing of the cell. Synonyms: Polymyxin B1-I sulfate; Polymyxin II Sulfate; Polymyxin B1 Isoleucine sulfate. Grade: ≥90.0%. Molecular formula: C56H98N16O13.xH2O4S. Mole weight: 1203.47 (free base). | |
| Polymyxin M | Polymyxin M is a cyclic peptide antibiotic produced by Bacillus polymyxa var. Ross. Synonyms: mattacin. Grade: 95%. CAS No. 6683-17-6. Molecular formula: C51H96N16O14. Mole weight: 1157.40. | |
| Polyoxin A | Polyoxin A is a nucleoside antifungal antibiotic produced by Str. cacaor var. asoensis and Str. piomogenus. Synonyms: (S-(E))-1-(5-((2-Amino-5-O-(aminocarbonyl)-2-deoxy-L-xylonoyl)amino)-1,5-dideoxy-1-(3,4-dihydro-5-(hydroxymethyl)-2,4-dioxo-1(2H)-pyrimidinyl)-beta-D-allofuranuronoyl)-3-ethylidene-2-azetidinecarboxylic acid. Grade: 95%. CAS No. 19396-03-3. Molecular formula: C23H32N6O14. Mole weight: 616.53. | |
| Polyoxin B | Polyoxin B is a nucleoside antifungal antibiotic produced by Str. cacaor var. asoensis and Str. piomogenus. Synonyms: Polyoxin AL; piomycin; (2S)-2-[[(2S,3S,4S)-2-amino-5-carbamoyloxy-3,4-dihydroxypentanoyl]amino]-2-[(2R,3S,4R,5R)-3,4-dihydroxy-5-[5-(hydroxymethyl)-2,4-dioxopyrimidin-1-yl]oxolan-2-yl]acetic acid. Grade: Assay 70%. CAS No. 19396-06-6. Molecular formula: C17H25N5O13. Mole weight: 507.41. | |
| Polyoxorim | Polyoxorim is a member of the class of polyoxins that is isolated from the soil organism Streptomyces cacaoi var. asoensis. Polyoxorim exhibits fungicidal properties and may be used on rice, industrial grounds, golf courses and parks. It has a role as an EC 2.4.1.16 (chitin synthase) inhibitor and an antifungal agrochemical. It is a polyoxin and an antibiotic fungicide. Synonyms: 5-[[2-Amino-5-O-(aminocarbonyl)-2-deoxy-L-xylonoyl]amino]-1-(5-carboxy-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,5-dideoxy-β-D-allofuranuronic acid; Polyoxin D; 1-{5-[{[2-amino-5-(carbamoyloxy)-3,4-dihydroxypentanoyl]amino}(carboxy)methyl]-3,4-dihydroxytetrahydrofuran-2-yl}-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid(non-preferred name); Polyoxin D, Streptomyces cacaoi var asoensis. Grade: ≥96%. CAS No. 22976-86-9. Molecular formula: C17H23N5O14. Mole weight: 521.39. | |
| (±)-Pomalidomide-[d3] (phthalimide-[4,5,6-d3]) | One of the isotopic labelled form of (±)-Pomalidomide, which is a potent TNF-α production inhibitor and could probably used as an antitumor agent. Synonyms: 4-Amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione-5,6,7-d3; CC-4047-d3. Grade: 95% by HPLC; 98% atom D. CAS No. 2093128-28-8. Molecular formula: C13H8D3N3O4. Mole weight: 276.27. | |
| Porcine dynorphin A (1-13) acetate | Porcine dynorphin A(1-13) acetate is an endogenous opioid peptide that preferentially activates κ opioid receptors. Synonyms: Dynorphin A Porcine Fragment 1-13 acetate; Dynorphin A (1-13) acetate; H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-OH.CH3CO2H; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-prolyl-L-lysyl-L-leucyl-L-lysine acetic acid; Dynorphin A (swine), 14-de-L-tryptophan-15-de-L-aspartic acid-16-de-L-asparagine-17-de-L-glutamine-, acetate (salt); Dynorphin A (pig), 14-de-L-tryptophan-15-de-L-aspartic acid-16-de-L-asparagine-17-de-L-glutamine-, acetate (salt); 1-13-Dynorphin A (swine) acetate. Grade: ≥95%. Molecular formula: C77H130N24O17. Mole weight: 1664.00. | |
| Porfiromycin | Porfiromycin is a quinone antibiotic produced by Str. ardus NRRL 2817. It has anti-Gram-positive and negative bacteria activity. It can inhibit sarcoma-180, Ehrlich ascites carcinoma, L-1210, H leukemia (solid type). The dose of inhibiting KB cell protein synthesis is 0.5 μg/mL. It is a bioreductive DNA alkylating agent that preferentially kills hypoxic tumor cells relative to other aerobic counterparts. Synonyms: N-Methylmitomycin C; NSC-56410; U-14743; Methylmitomycin; Methyl mitomycin C; Regamycin; Mitiromycin D; Porphyromycin; (1aS,8S,8aR,8bS)-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-1,5-dimethylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione. Grade: >98%. CAS No. 801-52-5. Molecular formula: C16H20N4O5. Mole weight: 348.35. | |
| Povidone-iodine | Povidone-iodine can be used as a topical preservative. It has activity against Gram-positive and Gram-negative bacteria, fungi, parasites, viruses and yeast. Uses: Use to clean contaminated wounds and for pre-operative preparation of the skin; used as a suspending agent, dispersing agent, and vehicle for pharmaceuticals, as a blood volume expander, topical antiseptic, and for infections of the skin and mucous membranes; the iodine can be radiolabeled for research applications. Synonyms: Betadine; Isodine; PVP Iodine. Grade: Available Iodine: 10%. CAS No. 25655-41-8. Molecular formula: (C6H9NO)x (I2)x. | |
| pp60 c-src (521-533) (phosphorylated) | pp60 c-src (521-533) (phosphorylated), the pp60 c-src carboxy-terminal phosphoregulatory peptide phosphorylated at Tyr527, participates in the regulation of kinase activity through binding intramolecularly or intermolecularly to the SH2 domain of the pp60 c-src protein. Synonyms: H-Thr-Ser-Thr-Glu-Pro-Gln-Tyr(PO3H2)-Gln-Pro-Gly-Glu-Asn-Leu-OH; L-threonyl-L-seryl-L-threonyl-L-alpha-glutamyl-L-prolyl-L-glutaminyl-O4-phosphono-L-tyrosyl-L-glutaminyl-L-prolyl-glycyl-L-alpha-glutamyl-L-asparagyl-L-leucine; L-Leucine, L-threonyl-L-seryl-L-threonyl-L-a-glutamyl-L-prolyl-L-glutaminyl-O-phosphono-L-tyrosyl-L-glutaminyl-L-prolylglycyl-L-a-glutamyl-L-asparaginyl-; Thr-Ser-Thr-Glu-Pro-Gln-O-Phosphono-Tyr-Gln-Pro-Gly-Glu-Asn-Leu-OH. Grade: >99%. CAS No. 149299-77-4. Molecular formula: C62H95N16O28P. Mole weight: 1543.48. | |
| P,p'-[p-phenylenebis(azo)]bisphenol | P,p'-[p-phenylenebis(azo)]bisphenol. CAS No. 21811-64-3. Molecular formula: C18H14N4O2. Mole weight: 318.30. | |
| PR 39 (porcine) | PR 39 (porcine) is a gene-encoded, proline-arginine-rich porcine antimicrobial peptide with multiple biological functions. It might function in the inflammatory milieu not only to kill bacteria, but also to aid in modulating the viability of inflammatory cells by regulating apoptosis. Uses: Anti-bacterial agents. Synonyms: PR39 (porcine); PR-39 (porcine); H-RRRPRPPYLPRPRPPPFFPPRLPPRIPPGFPPRFPPRFP-NH2; H-Arg-Arg-Arg-Pro-Arg-Pro-Pro-Tyr-Leu-Pro-Arg-Pro-Arg-Pro-Pro-Pro-Phe-Phe-Pro-Pro-Arg-Leu-Pro-Pro-Arg-Ile-Pro-Pro-Gly-Phe-Pro-Pro-Arg-Phe-Pro-Pro-Arg-Phe-Pro-NH2; L-arginyl-L-arginyl-L-arginyl-L-prolyl-L-arginyl-L-prolyl-L-prolyl-L-tyrosyl-L-leucyl-L-prolyl-L-arginyl-L-prolyl-L-arginyl-L-prolyl-L-prolyl-L-prolyl-L-phenylalanyl-L-phenylalanyl-L-prolyl-L-prolyl-L-arginyl-L-leucyl-L-prolyl-L-prolyl-L-arginyl-L-isoleucyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-L-prolyl-L-prolyl-L-arginyl-L-phenylalanyl-L-prolyl-L-prolyl-L-arginyl-L-phenylalanyl-L-prolinamide. Grade: >98%. CAS No. 139637-11-9. Molecular formula: C229H346N70O40. Mole weight: 4719.74. | |
| Pramlintide | Pramlintide, a synthetic version of amylin, is the first in a new class of pharmaceutical agents and exhibits high affinity for amylin, CGRP and calcitonin receptors (Ki values are 0.023, 3.8 and 5.1 nM respectively). Synonyms: AC 0137; AC 137; Symlin; Tripro-Amylin; riproamylin; Pramlintide; LS-181996; LS181996; Amylin. CAS No. 151126-32-8. Molecular formula: C171H267N51O53S2. Mole weight: 3949.42. | |
| Pravastatin Sodium | Pravastatin sodium is an HMG-CoA reductase inhibitor against sterol synthesis with IC50 of 5.6 μM. Synonyms: Mevalotin; Selektine; Elisor; (3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-[(2S)-2-methylbutanoyl]oxy-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate sodium; Lipostat; Bristacol. Grade: >98%. CAS No. 81131-70-6. Molecular formula: C23H35NaO7. Mole weight: 446.52. | |
| Praziquantel | Praziquantel, marketed as Biltricide, is an anthelmintic used in humans and animals for the treatment of tapeworms and flukes. Specifically, it is effective against schistosoma, Clonorchis sinensis the fish tapeworm Diphyllobothrium latum. Uses: Anthelmintics. Synonyms: 2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one; (+/-)-Praziquantel; Azinox; Biltricide; Cesol; Cysticide; Distocide; Droncit; Embay 8440; Prazinon; Pyquiton; Warmnil. Grade: >98%. CAS No. 55268-74-1. Molecular formula: C19H24N2O2. Mole weight: 312.41. | |
| Prepro VIP (111-122), human | It is the 111-122 amino acid fragment of prepro-vasoactive intestinal polypeptide (VIP). VIP is present in the peripheral and central nervous system as a non-adrenergic, non-cholinergic neurotransmitter or neuromodulator. Synonyms: PHM/VIP (Spacer Peptide); Preprovasoactive intestinal peptide (111-122); Val-Ser-Ser-Asn-Ile-Ser-Glu-Asp-Pro-Val-Pro-Val; L-valyl-L-seryl-L-seryl-L-asparagyl-L-isoleucyl-L-seryl-L-alpha-glutamyl-L-alpha-aspartyl-L-prolyl-L-valyl-L-prolyl-L-valine; N-(1-(N-(1-(N-(N-(N-(N-(N2-(N-(N-L-Valyl-L-seryl)-L-seryl)-L-asparginyl)-L-isoleucyl)-L-seryl)-L-alpha-glutamyl)-L-alpha-aspartyl)-L-propyl)-L-valyl)-L-propyl)-L-valine. Grade: 95%. CAS No. 123025-94-5. Molecular formula: C53H87N13O21. Mole weight: 1242.33. | |
| Prepro VIP (111-122), human acetate | Prepro VIP (111-122), human acetate is the 111-122 amino acid fragment of prepro-vasoactive intestinal polypeptide (VIP). VIP is present in the peripheral and central nervous system as a non-adrenergic, non-cholinergic neurotransmitter or neuromodulator. Synonyms: H-Val-Ser-Ser-Asn-Ile-Ser-Glu-Asp-Pro-Val-Pro-Val-OH.CH3CO2H; L-Valine, N-[1-[N-[1-[N-[N-[N-[N-[N2-[N-(N-L-valyl-L-seryl)-L-seryl]-L-asparaginyl]-L-isoleucyl]-L-seryl]-L-α-glutamyl]-L-α-aspartyl]-L-prolyl]-L-valyl]-L-prolyl]-, acetate salt (1:1); L-Valyl-L-seryl-L-seryl-L-asparaginyl-L-isoleucyl-L-seryl-L-α-glutamyl-L-α-aspartyl-L-prolyl-L-valyl-L-prolyl-L-valine acetate salt. Grade: ≥95%. CAS No. 2918768-00-8. Molecular formula: C53H87N13O21.C2H4O2. Mole weight: 1302.39. | |
| Prepro VIP (81-122), human | It is the 81-122 amino acid fragment of prepro-vasoactive intestinal polypeptide (VIP). Peptide histidine valine 42 (PHV-42) has been specified to precisely correspond to Prepro VIP (81-122), which reduces the force and frequency of spontaneous uterine contractions in isolated rats. Synonyms: His-Ala-Asp-Gly-Val-Phe-Thr-Ser-Asp-Phe-Ser-Lys-Leu-Leu-Gly-Gln-Leu-Ser-Ala-Lys-Lys-Tyr-Leu-Glu-Ser-Leu-Met-Gly-Lys-Arg-Val-Ser-Ser-Asn-Ile-Ser-Glu-Asp-Pro-Val-Pro-Val; L-histidyl-L-alanyl-L-alpha-aspartyl-glycyl-L-valyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-phenylalanyl-L-seryl-L-lysyl-L-leucyl-L-leucyl-glycyl-L-glutaminyl-L-leucyl-L-seryl-L-alanyl-L-lysyl-L-lysyl-L-tyrosyl-L-leucyl-L-alpha-glutamyl-L-seryl-L-leucyl-L-methionyl-glycyl-L-lysyl-L-arginyl-L-valyl-L-seryl-L-seryl-L-asparagyl-L-isoleucyl-L-seryl-L-alpha-glutamyl-L-alpha-aspartyl-L-prolyl-L-valyl-L-prolyl-L-valine; peptide histidine valine 42; Preprovasoactive intestinal peptide (81-122); Prepro-vip (81-122). Grade: >98%. CAS No. 111366-38-2. Molecular formula: C202H325N53O64S. Mole weight: 4552.13. | |
| Pressinoic Acid | Pressinoic Acid is a synthetic hexapeptide with strong corticotrophin-releasing activity. It is also an oxytocin inhibitor and induces maternal behavior. Synonyms: Cys-Tyr-Phe-Gln-Asn-Cys (Disulfide bridge: Cys1-Cys6); L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteine (1->6)-disulfide; 1-6-Oxytocin, 3-L-phenylalanine-. Grade: >95%. CAS No. 35748-51-7. Molecular formula: C33H42N8O10S2. Mole weight: 774.86. | |
| Prezatide Copper Acetate | Prezatide copper acetate is a complex composed of tripeptide prezatide, acetic acid and copper ion. Prezatide is used for skin care, and has the potential to treat chronic obstructive pulmonary disease and metastatic colon cancer. Uses: This product is a functional skin care material with anti-inflammatory, light scar and wrinkle removal. it has good water solubility and can be added directly below 40°c. in the water phase of the cosmetic formula, it is added in the final stage of the formula. used in personal skin care products with anti-inflammatory and anti-allergic effects, such as essence lotion, cream, facial mask and sunscreen, etc. Synonyms: L-Lysine, N-(N-glycyl-L-histidyl)-, copper complex; Cuprate(1-), (glycyl-L-histidyl-κN-L-lysinato)[glycyl-κN-L-histidyl-κN ,κN-Llysinato(2-)]-, hydrogen, diacetate; Cuprate(1-), [N-(N-glycyl-L-histidyl)-L-lysinato][N-(N-glycyl-L-histidyl)-L-lysinato(2-)]-, hydrogen, diacetate; Iamin; PC 1020 acetate; GHK2-Cu Acetate. CAS No. 130120-57-9. Molecular formula: C32H54CuN12O12. Mole weight: 862.39. | |
| Pristinamycin | Pristinamycin is a complex of antibiotics produced by streptomyces pristinaespiralis, containing two components Pristinamycin IA and Pristinamycin IIA. Pristinamycin IA is a macrolide, and Pristinamycin IIA (streptogramin A) is a depsipeptide. Pristinamycin has been indicated for the treatment of MRSA. Synonyms: Pyostacine; Stafac; Pristinamycine; Staphylomycin; Virginiamycin. CAS No. 270076-60-3. Molecular formula: C73H89N11O17. Mole weight: 1392.55. | |
| Pristinamycin IIA | Pristinamycin IIA is an ester peptide antibiotic produced by Str. pristinaespiralis 5647 (NRRL 2958). Activity against gram-positive bacteria. Uses: Anti-bacterial agents. Synonyms: virginiamycin M1; Streptogramin A; Mikamycin A; Ostreogrycin a. Grade: ≥ 95%. CAS No. 21411-53-0. Molecular formula: C28H35N3O7. Mole weight: 525.59. | |
| Pristinamycin IIB | Pristinamycin IIB is an ester peptide antibiotic produced by Str. pristinaespiralis 5647 (NRRL 2958). Activity against gram-positive bacteria. Synonyms: Volpristin; Virginiamycin M2. CAS No. 21102-49-8. Molecular formula: C28H37N3O7. Mole weight: 527.61. | |
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