BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| (R)-MG132 | (R)-MG-132 is a reversible, cell permeable and selective tripeptide aldehyde proteasome inhibitor (IC50 = 0.22 μM), the most potent stereoisomer of MG-132. It exhibits cytostatic and cytotoxic effects in tumor cells in vitro. Synonyms: (R)-MG132; (R)-MG 132; MolPort-009-019-420; Cbz-L-leu-D-leu-L-leu-H; KS-000006AS; N-[(Phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-3-methylbutyl]-D-leucinamide. Grade: ≥97% by HPLC. CAS No. 1211877-36-9. Molecular formula: C26H41N3O5. Mole weight: 475.62. |  |
| (R)-N-(2-acetyl-1,2,3,4-tetrahydro-5,8-dimethoxy-2-naphthalenyl)-acetamide-[13C] | Intermediate in the preparation of labelled Amrubicin. Synonyms: (R)-N-(2-acetyl-1,2,3,4-tetrahydro-5,8-dimethoxy-2-naphthalenyl)-acetamide-13C; N-[(2R)-2-Acetyl-1,2,3,4-tetrahydro-5,8-dimethoxy-2-naphthalenyl]-acetamide-13C. CAS No. 1391067-98-3. Molecular formula: C15[13C]H21NO4. Mole weight: 292.33. | |
| Rolitetracycline | Rolitetracycline is a semi-synthetic tetracycline antibiotic. It has broad-spectrum Gram-positive activity in the body. Uses: Antibacterial. Synonyms: Reverin; Syntetrin; Rolitetraciclina; Rolitetracyclinum; Pyrrolidino-Methyl-Tetracycline. Grade: >98% by HPLC. CAS No. 751-97-3. Molecular formula: C27H33N3O8. Mole weight: 527.56. | |
| Romidepsin | Romidepsin strongly inhibits HDAC1 and HDAC2 with IC50 of 1.6 nM and 3.9 nM, respectively, but is relatively weak in inhibiting HDAC4 and HDAC6 with IC50 25 nM and 790 nM, respectively. Uses: For research used only. Synonyms: Istodax; FK228; FK 228; FK-228; Chromadax; Antibiotic FR 901228; FR901228; FR-901228; NSC-630176; L-Valine, N-((3S,4E)-3-hydroxy-7-mercapto-1-oxo-4-heptenyl)-D-valyl-D-cysteinyl-(2Z)-2-amino-2-butenoxyl-, (4-1)-lactone, cyclic (1-2)-disulfide. Grade: >98%. CAS No. 128517-07-7. Molecular formula: C24H36N4O6S2. Mole weight: 540.69. | |
| Roridin A | It has antifungal effect, and it can inhibit 50% of mast cell tumor P815 cells at 0.001 μg/mL in vitro. Synonyms: Roridine A; Roridan A; NSC 200737; Antibiotic 379X; Verrucarin A, 7'-deoxo-7'-(1-hydroxyethyl)-. Grade: ≥98%. CAS No. 14729-29-4. Molecular formula: C29H40O9. Mole weight: 532.62. | |
| Roseoflavin | An antibacterial pigment isolated from streptomyces davawensis; an anti-metabolite of riboflavin; mimic riboflavin in flavin biosynthesis; an important regulator of bacterial gene expression by binding to untranslated regions of RNA, so-called ribo-switching sites. Synonyms: 8-demethyl-8-(dimethylamino)riboflavin; 1-Deoxy-1-[8-(Dimethylamino)-7-Methyl-2,4-Dioxo-3,4-Dihydrobenzo[g]pteridin-10(2h)-Yl]-D-Ribitol; Roseoflavine; 8-Dimethylaminoriboflavin. Grade: >98% by HPLC. CAS No. 51093-55-1. Molecular formula: C18H23N5O6. Mole weight: 405.40. | |
| Rosin, maleated, polymer with bisphenol A and formaldehyde | Rosin, maleated, polymer with bisphenol A and formaldehyde. Grade: 95%. CAS No. 68188-63-6. | |
| Rosin, maleic anhydride, tall oil fatty acids, zinc oxide, calcium oxide resinate | Rosin, maleic anhydride, tall oil fatty acids, zinc oxide, calcium oxide resinate. Grade: 95%. CAS No. 96774-55-9. | |
| Rosin polymer with diethylene glycol, ethylene glycol, glycerol, isophthalic acid, polyethylene glycol ether with bisphenol A (2:1) and terephthalic acid | Rosin polymer with diethylene glycol, ethylene glycol, glycerol, isophthalic acid, polyethylene glycol ether with bisphenol A (2:1) and terephthalic acid. Grade: 95%. CAS No. 114352-07-7. | |
| Roxithromycin Impurity C | An impurity found in the macrolide antibiotic, Clarithromycin. It exhibits antibacterial properties. Synonyms: 9-Erythromycin 9-Oxime; 9-Erythromycin A Oxime; Erythromycin Oxime; Roxithromycin Impurity C; Clarithromycin EP Impurity J. Grade: >95%. CAS No. 13127-18-9. Molecular formula: C37H68N2O13. Mole weight: 748.94. | |
| Roxithromycin Impurity F | A metabolite of the macrolide antibiotic, Roxithromycin. Synonyms: (9E)-9-[O-[(2-Methoxyethoxy)methyl]oxime]-N-demethyl Erythromycin; (E)-N-Demethylroxithromycin; N-Demethylroxithromycin; RU 44981; Roxithromycin Impurity 6; Roxithromycin EP Impurity F. Grade: >95%. CAS No. 118267-18-8. Molecular formula: C40H74N2O15. Mole weight: 823.02. | |
| (R)-Oxybutynin-[d11] | A labelled impurity of Oxybutynin which belongs to a class of drugs called anticholinergics/antimuscarinics. Synonyms: 4-(Diethylamino)but-2-yn-1-yl (R)-2-(cyclohexyl-d11)-2-hydroxy-2-phenylacetate; (R)-Oxybutynin D11; Benzeneacetic acid, α-cyclohexyl-d11-α-hydroxy-, 4-(diethylamino)-2-butynyl ester, (αR)-; (-)-Oxybutynin-d11; (R)-Oxybutynin-d11; Aroxybutynin-d11. Grade: >95%. Molecular formula: C22H20NO3D11. Mole weight: 368.56. | |
| (R)-(-)-Phenylephrine-[d3] Hydrochloride | (R)-(-)-Phenylephrine-[d3] Hydrochloride is the labelled salt of Phenylephrine, which is a selective α1-adrenergic receptor agonist of the phenethylamine class. Synonyms: (R)-(-)-Phenylephrine D3 Hydrochloride; (R)-(-)-Phenylephrine-2,4,6-d3 HCl; Phenylephrine D3 hydrochloride; 3-[(1R)-1-hydroxy-2-(methylamino)ethyl](2,4,6-D3)phenol hydrchloride; (αR)-3-Hydroxy-α-[(methylamino)methyl]benzenemethanol-d3 Hydrochloride; (-)-m-Hydroxy-α-[(methylamino)methyl]benzyl Alcohol-d3 Hydrochloride. Grade: >95%. CAS No. 1276197-50-2. Molecular formula: C9H11D3ClNO2. Mole weight: 206.68. | |
| (R)-Praziquantel-[d11] | (R)-Praziquantel-[d11] is the labelled analogue of (R)-Praziquantel, which is the active enantiomer of Praziquantel. Praziquantel can be used for the treatment of a number of types of parasitic worm infections. Specifically it is used for schistosomiasis, clonorchiasis, opisthorchiasis, tapeworm infections, cysticercosis, hydatid disease, and other fluke infections. Synonyms: (R)-Praziquantel-d11; (11bR)-2-(Cyclohexyl-1,2,2,3,3,4,4,5,5,6,6-d11-carbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one. Grade: 98% by HPLC. CAS No. 1399880-38-6. Molecular formula: C19H13D11N2O2. Mole weight: 323.48. | |
| RS 09 | RS 09 is a TLR4 agonist. Synonyms: Ala-Pro-Pro-His-Ala-Leu-Ser; RS09; RS-09; L-Serine, L-alanyl-L-prolyl-L-prolyl-L-histidyl-L-alanyl-L-leucyl-; L-Alanyl-L-prolyl-L-prolyl-L-histidyl-L-alanyl-L-leucyl-L-serine. Grade: ≥95%. CAS No. 1449566-36-2. Molecular formula: C31H49N9O9. Mole weight: 691.78. | |
| RS09 2TFA | RS09 2TFA, a TLR4 agonist, is an adjuvant that promotes NF-κB nuclear translocation and induces inflammatory cytokine secretion in RAW264.7 macrophages in vitro. RS09 increases antibody production in the vaccine environment. Synonyms: H-Ala-Pro-Pro-His-Ala-Leu-Ser-OH.2TFA; L-alanyl-L-prolyl-L-prolyl-L-histidyl-L-alanyl-L-leucyl-L-serine trifluoroacetic acid; RS 09 2TFA. Grade: ≥95%. Molecular formula: C35H51F6N9O13. Mole weight: 919.82. | |
| (R,S)-1-Methyl-3-nicotinoylpyrrolidone-[13C6] | (R,S)-1-Methyl-3-nicotinoylpyrrolidone-[13C6]. Uses: An amino alcohol metabolite of nicotine, and precursor to nnk. Synonyms: 1-Methyl-3-(3'-pyridylcarbonyl-1,2',3',4',5',6'-13C6-pyrrolidinone. Grade: 95% atom 13C. CAS No. 1189492-36-1. Molecular formula: C5[13C]6H12N2O2. Mole weight: 210.18. | |
| (R,S)-1-Methyl-3-nicotinoylpyrrolidone-[d3] | (R,S)-1-Methyl-3-nicotinoylpyrrolidone-[d3]. Synonyms: (+/-)-1-Methyl-3-(3-pyridinylcarbonyl)-2-pyrrolidinone-d3. CAS No. 86270-95-3. Molecular formula: C11H9D3N2O2. Mole weight: 207.24. | |
| (R,S)-1-Tosyl Glycerol-[d5] | (R,S)-1-Tosyl Glycerol-[d5]. Uses: Protected, labelled glycerol. Synonyms: 1-Tosyloxy-2,3-propanediol-d5; 2,3-Dihydroxypropyl Tosylate-d5; p-Toluenesulfonic Acid Glyceryl Ester-d5; 1-p-Toluenesulfonate Glycerol-d5; 1,2,3-Propanetriol 1-(4-Methylbenzenesulfonate)-d5. CAS No. 928623-32-9. Molecular formula: C10H9D5O5S. Mole weight: 251.31. | |
| (R,S)-Anabasine-[2,4,5,6-d4] | (R,S)-Anabasine-[2,4,5,6-d4] is the labelled analogue of (R,S)-Anabasine, which is a nicotinic receptor agonist. Synonyms: (R,S)-Anabasine-2,4,5,6-d4; (R,S)-3-(2-Piperidinyl)pyridine-2,4,5,6-d4; (R,S)-Anabaseine-d4. Grade: ≥95%; ≥98% atom D. CAS No. 1020719-08-7. Molecular formula: C10H10D4N2. Mole weight: 166.26. | |
| (R,S)-Anatabine-[2,4,5,6-d4] | (R,S)-Anatabine-[2,4,5,6-d4] is the labelled analogue of (R,S)-Anatabine, which is a metabolite of Nicotine. Synonyms: (R,S)-Anatabine-2,4,5,6-D4; (+/-)-1,2,3,6-Tetrahydro-2,3'-bipyridine-d4; (+/-)-Anatabine-d4; DL-Anatabine-d4; Rac-Anatabine-d4; Racemic Anabasine-D4. Grade: ≥95%. CAS No. 1020719-11-2. Molecular formula: C10H8D4N2. Mole weight: 164.24. | |
| (R,S)-N-Nitroso Anabasine-[d4] | (R,S)-N-Nitroso Anabasine-[d4] is a labelled metabolite of Nicotine, which is a potent parasympathomimetic stimulant. Uses: A labelled metabolite of tobacco, a specific n-nitrosamines. Synonyms: NAB-d4; 5-(1-Nitroso-2-piperidinyl)pyridine-2,3,4,6-d4. Grade: 95%. CAS No. 1020719-68-9. Molecular formula: C10H9D4N3O. Mole weight: 195.25. | |
| (R,S)-N-Nitroso Anatabine-[2,4,5,6-d4] | (R,S)-N-Nitroso Anatabine-[2,4,5,6-d4] is the labelled analogue of (R,S)-N-Nitroso Anatabine, which is a metabolite of Nicotine. Nicotine is a potent parasympathomimetic stimulant. Synonyms: (R,S)-N-Nitroso Anatabine-2,4,5,6-D4; NAT-d4; 1,2,3,6-Tetrahydro-1-nitroso-2,3'-bipyridine-2',4',5',6'-d4. Grade: >95%. CAS No. 1020719-69-0. Molecular formula: C10H7D4N3O. Mole weight: 193.24. | |
| (R,S)-Norcotinine-pyridyl-[d4] | (R,S)-Norcotinine-pyridyl-[d4] is the labelled metabolite of (+/-)-Cotinine. Synonyms: 5-(3-Pyridinyl)-2-pyrrolidinone-pyridyl-d4; (RS)-Norcotinine-d4; (+/-)-Demethylcotinine-d4; (+/-)-Norcotinine-d4. Grade: 95%. CAS No. 1020719-70-3. Molecular formula: C9H6D4N2O. Mole weight: 166.21. | |
| (R)-(+)-Styrene-[d5] Oxide | (R)-(+)-Styrene-[d5] Oxide. Uses: A labelled main metabolite of styrene (s687790), catalyzed by epoxide hydrolase. Synonyms: (R)-Phenyl-d5-oxirane; (2R)-2-(Phenyl-d5)-oxirane; (R)-(+)-(Epoxyethyl)benzene-d5; (2R)-2-(Phenyl-d5)oxirane; (R)-Epoxystyrene-d5; (R)-Phenylethylene-d5 Oxide. CAS No. 192506-02-8. Molecular formula: C8H3D5O. Mole weight: 125.18. | |
| (R)-(-)-Tamsulosin-[d5] Hydrochloride | One of the isotopic labelled form of (R)-(-)-Tamsulosin, which is an α1-adrenoceptor antagonist and could be used against benign prostatic hypertrophy. Synonyms: 5-[(2R)-2-[[2-(-Ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzenesulfonamide-d5 Hydrochloride; Flomax-d5; Harnal-d5; Omnic-d5; Pradif-d5; YM 12617-1-d5; YM 617-d5; Yutanal-d5; (R)-(-)-Tamsulosin D5 Hydrochloride. Grade: >98%. Molecular formula: C20H24D5ClN2O5S. Mole weight: 450. | |
| Rugulosin ((+) form) | An intense yellow pigment produced by some species of penicillium, aspergillus and the fungal symbiotants of some lichens; shows antibacterial and insecticidal activity; an inhibitor of RNA Polymerase and Rnase. Synonyms: (+)-Rugulosin; Radicalisin; NSC 160880; 5H,13a,5a,14-[1,2,3,4]Butanetetraylcycloocta[1,2-b:5,6-b']dinaphthalene-5,8,13,16(14H)-tetrone, 1,7,9,15,17,20-hexahydroxy-3,11-dimethyl-. Grade: >98% by HPLC. CAS No. 23537-16-8. Molecular formula: C30H22O10. Mole weight: 542.49. | |
| Rugulotrosin A | It is a symmetric dimer antibiotic isolated from an uncharacterised species of penicillium. It displays significant antibacterial activity against a wide range of gram-positive bacteria. Synonyms: (4R,4'R,4aR,4'AR,7R)-Rel-2,2',3,3',4,4',9,9'-Octahydro-1,1',4,4',8,8'-Hexahydroxy-6,6'-Dimethyl-9,9'-Dioxo-[7,7'-Bi-4aH-Xanthene]-4a,4'A-Dicarboxylic Acid Dimethyl Ester. Grade: >98% by HPLC. CAS No. 685135-81-3. Molecular formula: C32H30O14. Mole weight: 638.57. | |
| RVD-Hpα | RVD-Hpα is a neuropeptide that acts as a selective CB1 receptor agonist. It has been demonstrated to increase the phosphorylation of ERK1/2 levels or release of intracellular Ca2+. CAS No. 1193362-76-3. Molecular formula: C65H105N19O17. Mole weight: 1424.66. | |
| RVD-Hpα acetate | RVD-Hpα acetate is a neuropeptide that acts as a selective CB1 receptor agonist. It has been demonstrated to increase the phosphorylation of ERK1/2 levels or release of intracellular Ca2+. It is also a high-affinity CB2 positive allosteric modulator (Ki = 50 nM). Synonyms: H-Arg-Val-Asp-Pro-Val-Asn-Phe-Lys-Leu-Leu-Ser-His-OH.CH3CO2H; L-arginyl-L-valyl-L-alpha-aspartyl-L-prolyl-L-valyl-L-asparagyl-L-phenylalanyl-L-lysyl-L-leucyl-L-leucyl-L-seryl-L-histidine. Grade: ≥95%. Molecular formula: C67H109N19O19. Mole weight: 1484.71. | |
| (R)-Viloxazine-[d5] Hydrochloride | (R)-Viloxazine-[d5] Hydrochloride is the labelled (R)-isomer of Viloxazine which is used as an antidepressant. Uses: The labelled (r)-isomer of. Synonyms: (R)-2-[((2-Ethoxy-d5)phenoxy)methyl]morpholine Hydrochloride; (R)-2-[(2-Ethoxy-d5)phenoxymethyl]tetrahydro-1,4-oxazine Hydrochloride. Grade: 95%. CAS No. 1246815-04-2. Molecular formula: C13H15D5ClNO3. Mole weight: 278.79. | |
| S-(1,2-Dicarboxyethyl)glutathione | It shows anti-inflammatory and anti-anaphylactic effects in vivo and inhibits histamine release from rat mast cells in vitro. Synonyms: S-(alpha,beta-Dicarboxyethyl)glutathione; H-Glu(Cys(1,2-dicarboxyethyl)-Gly-OH)-OH. Grade: 95%. CAS No. 1115-52-2. Molecular formula: C14H21N3O10S. Mole weight: 423.40. | |
| (S)-2-Amino-2-(1-methylcyclopropyl)acetic acid hydrochloride | (2S)-2-Amino-2-(1-methylcyclopropyl)acetic acid hydrochloride is an amino acid antibiotic produced by Micromonospora miyakonensis PA-4046. It has activity against Escherichia coli. Synonyms: Antibiotic PA 40461 hydrochloride; L-2-(1-Methylcyclopropyl)glycine hydrochloride; PA-4046-I hydrochloride; (S)-2-(1-methylcyclopropyl)glycine hydrochloride; (alphaS)-alpha-Amino-1-methylcyclopropaneacetic acid hydrochloride. Grade: 97.0%. CAS No. 1523541-83-4. Molecular formula: C6H11NO2.HCl. Mole weight: 165.62. | |
| (S)-2-Amino-3-(methylamino)propanoic acid hydrochloride | A neurotoxic glutamate agonist found in cyanobacteria. Synonyms: beta-N-Methylamino-L-alanine hydrochloride; L-BMAA Hydrochloride; (S)-2-amino-3-(methylamino)propanoic acid monohydrochloride; H-Dap(Me)-OH HCl; S-(+)-β-Methyl-α,β-diaminopropionic Acid Hydrochloride; BMAA Hydrochloride; β-Methylamino-L-alanine Hydrochloride (1:1); L-Alanine, 3-(methylamino)-, hydrochloride (1:1); 3-(Methylamino)-L-alanine hydrochloride (1:1). Grade: ≥95%. CAS No. 16012-55-8. Molecular formula: C4H11ClN2O2. Mole weight: 154.59. | |
| (S)-2-Methyl-[d3]-butanoyl Chloride | (S)-2-Methyl-[d3]-butanoyl Chloride. Synonyms: (S)-2-Methyl-d3-butyryl Chloride; (S)-2-Methyl-d3-butanoic Acid Chloride; (S)-2-Methylbutyric acid chloride-d3. Grade: 95%. CAS No. 1217722-29-6. Molecular formula: C5H6D3ClO. Mole weight: 123.59. | |
| (S)-3-(2-Chloro-4-nitro-1H-imidazol-1-yl)-2-(4-trifluoromethoxybenzyloxy)propyl 4-Methoxy-3-(4-trifluoromethoxybenzyl)benzoate | (S)-3-(2-Chloro-4-nitro-1H-imidazol-1-yl)-2-(4-trifluoromethoxybenzyloxy)propyl 4-Methoxy-3-(4-trifluoromethoxybenzyl)benzoate is a building block used in the synthesis of pharmaceuticals. Molecular formula: C30H24ClF6N3O8. Mole weight: 703.97. | |
| (S)-3-((2R,3S,5S)-5-Allyl-3-(benzyloxy)-4-oxotetrahydrofuran-2-yl)propane-1,2-diyl dibenzoate | (S)-3-((2R,3S,5S)-5-Allyl-3-(benzyloxy)-4-oxotetrahydrofuran-2-yl)propane-1,2-diyl dibenzoate, a chemical compound demonstrating properties for anti-cancer drug development, exhibits pronounced inhibition of cancer cells through modulation of the cell cycle and promotion of apoptosis. Current research explores its potential for treating conditions pertaining to inflammation and oxidative stress. CAS No. 871348-04-8. Molecular formula: C31H30O7. Mole weight: 514.6. | |
| (S)-(+)-3-Hydroxytetrahydrofuran-[d4] | (S)-(+)-3-Hydroxytetrahydrofuran-[d4]. Synonyms: 3S-Hydroxytetrahydrofuran-d4; (S)-Tetrahydro-3-furanol-d4; (+)-3-Hydroxytetrahydrofuran-d4. CAS No. 1217718-57-4. Molecular formula: C4H4D4O2. Mole weight: 92.13. | |
| (S)-3-Isopropylamino-1,2-propanediol | An impurity of Metoprolol. Metoprolol is a selective beta-1 receptor blocker used primarily to treat hypertension, angina pectoris, heart failure, and certain arrhythmias. Synonyms: (S)-1-Isopropylaminopropanediol; (S)-3-(Isopropylamino)propane-1,2-diol; (-)-3-Isopropylamino-1,2-propanediol; (2S)-3-[(1-Methylethyl)amino]-1,2-propanediol; (2S)-3-[(Propan-2-yl)amino]propane-1,2-diol; 1,2-Propanediol 3-[(1-methylethyl)amino]-, (2S)-. Grade: ≥95%. CAS No. 90742-94-2. Molecular formula: C6H15NO2. Mole weight: 133.19. | |
| (S)-4-Benzyl-3-propionyl-2-oxazolidinone-[d3] | (S)-4-Benzyl-3-propionyl-2-oxazolidinone-[d3]. Uses: Intermediate in the preparation of labelled albaconazole. Synonyms: (4S)-3-(1-Oxopropyl)-4-(phenylmethyl)-2-oxazolidinone-d3; (+)-4-Benzyl-3-propionyl-2-oxazolidinone-d3; (4S)-4-Benzyl-3-propanoyloxazolidin-2-one-d3; (4S)-4-Benzyl-3-propionyl-1,3-oxazolidin-2-one-d3; (S)-N-Propionyl-4-benzyl-1,3-oxazolidin-2-one-d3; 3-[1-Oxopropyl]-4(S)-(phenylmethyl)-2-oxazolidinone-d3. CAS No. 156451-08-0. Molecular formula: C13H12D3NO3. Mole weight: 236.28. | |
| (S)-4-Ethyl-4-hydroxy-7,8-dihydro-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione | (S)-4-Ethyl-4-hydroxy-7,8-dihydro-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione is a key intermediate for the synthesis of irinotecan and camptothecin analogues. It is also an ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: 1H-Pyrano[3,4-f]indolizine-3,6,10(4H)-trione, 4-ethyl-7,8-dihydro-4-hydroxy-, (4S)-; (4S)-4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione; Irinotecan Intermediates (94-5); 1H-Pyrano[3,4-f]indolizine-3,6,10(4H)-trione, 4-ethyl-7,8-dihydro-4-hydroxy-, (S)-; (4S)-4-Ethyl-4-hydroxy-7,8-dihydro-1H-pyrano[3,4-f]indolizine-3,6,10(4H)trione. Grade: ≥95%. CAS No. 110351-94-5. Molecular formula: C13H13NO5. Mole weight: 263.25. | |
| S-4-Methoxybenzyl-L-penicillamine | S-4-Methoxybenzyl-L-penicillamine is a derivative of D-Penicillamine, which is a penicillin metabolite used in the treatment of Wilson's disease, Cystinuria, Scleroderma and arsenic poisoning. Synonyms: L-Pen(pMeOBzl)-OH; H-β,β-Dimethyl-L-Cys(pMeOBzl)-OH; H-Pen(Mob)-OH; 3-[[(4-Methoxyphenyl)methyl]thio]-L-valine; (R)-2-Amino-3-((4-methoxybenzyl)thio)-3-methylbutanoic acid; 3-[(4-Methoxybenzyl)sulfanyl]-L-valine; L-Valine, 3-[[(4-methoxyphenyl)methyl]thio]-. Grade: ≥95%. CAS No. 387868-34-0. Molecular formula: C13H19NO3S. Mole weight: 269.34. | |
| S-4-Methylbenzyl-L-penicillamine | S-4-Methylbenzyl-L-penicillamine is a methylbenzyl L analogue of D-Penicillamine, which is Penicillin metabolite used in the treatment of Wilson's disease, Cystinuria, Scleroderma and arsenic poisoning. Synonyms: 3-[[(4-Methylphenyl)methyl]thio]-L-valine; (R)-2-Amino-3-methyl-3-((4-methylbenzyl)thio)butanoic acid; L-Valine, 3-[[(4-methylphenyl)methyl]thio]-; 3-[(4-Methylbenzyl)sulfanyl]-L-valine; H-β,β-Dimethyl-L-cys(pmebzl)-OH. Grade: 98%. CAS No. 1039102-11-8. Molecular formula: C13H19NO2S. Mole weight: 253.36. | |
| (S)-4-Phenyloxazolidin-2-one | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L12) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: 2-Oxazolidinone, 4-phenyl-, (4S)-; (4S)-(+)-4-Phenyl-1,3-oxazolidin-2-one; (4S)-4-Phenyl-2-oxazolidinone; 2-Oxazolidinone, 4-phenyl-, (S)-; (+)-4-Phenyl-2-oxazolidinone; (4S)-4-Phenyloxazolidin-2-one; (S)-(+)-4-Phenyl-2-oxazolidinone; (S)-4-Phenyl-1,3-oxazolidin-2-one; (S)-4-Phenyl-2-oxazolidinone; (4S)-POZ; (S)-POZ. Grade: ≥95%. CAS No. 99395-88-7. Molecular formula: C9H9NO2. Mole weight: 163.18. | |
| Saccharocarcin A | An unusual tetronic acid structurally related to kijanimicin, chlorothricin, tetrocarcin and versipelostatin; has pronounced activity against gram positive bacteria and chlamydia trachomatis; inhibits transcription from the promoter of GRP78; appears to target the phosphatidylinositide-3-kinase/akt signalling pathway. Synonyms: 10-[[4-(acetylamino)-2,4,6-trideoxy-3-C-methylhexopyranosyl]oxy]-4-[[O-2,6-dideoxyhexopyranosyl-(1→4)-O-2,6-dideoxy-3-O-(tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)hexopyranosyl-(1→4)-2,6-dideoxyhexopyranosyl]oxy]-15-ethyl-2,3,4,4a,6a,9,10,12a,15,16,20a,20b-dodecahydro-21-hydroxy-1,3,7,9,11,20a-hexamethyl-18H-16a,19-metheno-16aH-benzo[b]naphth[2,1-j]oxacyclotetradecin-18,20(1H)-dione. Grade: >95% by HPLC. CAS No. 158475-32-2. Molecular formula: C67H101NO20. Mole weight: 1240.51. | |
| Saccharocarcin B | An unusual tetronic acid structurally related to kijanimicin, chlorothricin, tetrocarcin and versipelostatin; has pronounced activity against gram positive bacteria and chlamydia trachomatis; inhibits transcription from the promoter of GRP78; appears to target the phosphatidylinositide-3-kinase/akt signalling pathway. Synonyms: 10-[[4-(acetylamino)-2,4,6-trideoxy-3-C-methylhexopyranosyl]oxy]-4-[[O-2,6-dideoxyhexopyranosyl-(1→4)-O-2,6-dideoxy-3-O-(tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)hexopyranosyl-(1→4)-2,6-dideoxyhexopyranosyl]oxy]-2,3,4,4a,6a,9,10,12a,15,16,20a,20b-dodecahydro-21-hydroxy-1,3,7,9,11,20a-hexamethyl-15-propyl-18H-16a,19-metheno-16aH-benzo[b]naphth[2,1-j]oxacyclotetradecin-18,20(1H)-dione. Grade: >99% by HPLC. CAS No. 158475-33-3. Molecular formula: C68H103NO20. Mole weight: 1254.54. | |
| S-Adenosyl-L-cysteine | S-Adenosyl-L-cysteine. Synonyms: Adenosine, 5'-S-(2-amino-2-carboxyethyl)-5'-thio-, (R)-; S-(5'-Deoxyadenosin-5'-yl)-L-cysteine; 5'-S-Adenosyl-L-cysteine; Adenosylcysteine; S-(((2S,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)-L-cysteine. CAS No. 35899-53-7. Molecular formula: C13H18N6O5S. Mole weight: 370.38. | |
| Safracin B | Safracin B is a new antibiotic from the family of Safracin produced by Pseudomonas fluorescens A2-2. Safracin B exhibits broad spectrum antimicrobial and strong antitumor activities. Synonyms: Antibiotic EM 5519; Antibiotic Y 16482α. Grade: ≥85% (HPLC). CAS No. 87578-99-2. Molecular formula: C28H36N4O7. Mole weight: 540.61. | |
| SAH-SOS1A | SAH-SOS1A is a cell-permeable, stabilized hydrocarbon-stapled alpha helical peptide that acts as a K-Ras/son of sevenless 1 (SOS1) interaction inhibitor. It binds within nucleotide binding pocket of wild-type and mutant K-Ras. CAS No. 1652561-87-9. Molecular formula: C100H159N27O28. Mole weight: 2187.53. | |
| Salinomycin | It is an antibiotic produced by the strain of Str. albus 80614. It has anti-gram-positive bacteria and mycobacterium effects. It also has the effect against gram-negative bacteria and fungi but the effect is weak. It has a therapeutic effect on chickens infected with coccidiococci. Synonyms: Procoxacin; Coxistac; AHR 3096; AHR3096; AHR-3096; HSDB 7032; HSDB7032; HSDB-7032; K 364; K364; K-364; Bio-Cox; Sacox; Salocin; 1,?6,?8-Trioxadispiro[4.1.5.?3]?pentadecane; Antibiotic 61477; Salinomicina. Grade: 98%. CAS No. 53003-10-4. Molecular formula: C42H70O11. Mole weight: 751.01. | |
| Salinomycin Sodium | Salinomycin Sodium is an antibiotic produced by the strain of Str. albus 80614. It has anti-gram-positive bacteria and mycobacterium effects. It also has the effect against gram-negative bacteria and fungi but the effect is weak. It has a therapeutic effect on chickens infected with coccidiococci. It can be used to prevent chicken coccidiosis. Synonyms: Salinomycin sodium salt; Sodium salinomycin; Procoxacin sodium salt; Coxistac sodium salt; Bio-Cox sodium salt; Sacox sodium salt; Salinomicina sodium salt. Grade: >98%. CAS No. 55721-31-8. Molecular formula: C42H69NaO11. Mole weight: 772.99. | |
| SAMS | SAMS peptide, a synthetic peptide substrate for AMPK based on the sequence around Ser79 on acetyl-CoA carboxylase, is more selective for the kinase than acetyl CoA carboxylase itself, and provides a convenient and sensitive assay for AMPK. Synonyms: (Ser76, Arg86.87)-ACC-α (73-87) (dephosphorylated) (E.coli, rat); (Ser76, Arg86.87)-Acetyl-CoA Carboxylase 1 (73-87) (dephosphorylated) (E.coli, rat); (Ser77, Arg87.88)-ACC-α (74-88) (dephosphorylated) (bovine, ovine); (Ser77, Arg87.88)-Acetyl-CoA Carboxyla; H-His-Met-Arg-Ser-Ala-Met-Ser-Gly-Leu-His-Leu-Val-Lys-Arg-Arg-OH; L-histidyl-L-methionyl-L-arginyl-L-seryl-L-alanyl-L-methionyl-L-seryl-glycyl-L-leucyl-L-histidyl-L-leucyl-L-valyl-L-lysyl-L-arginyl-L-arginine. Grade: >95%. CAS No. 125911-68-4. Molecular formula: C74H131N29O18S2. Mole weight: 1779.15. | |
| Sancycline | Sancycline is a tetracycline bacteriostatic antibiotic which also binds to the Tet repressor protein (TetR). Sancycline acts by reversibly binding to the 30S ribosomal subunit and inhibiting protein translation by blocking entry of aminoacyl-tRNA into the ribosome A site. Synonyms: Minocycline EP Impurity B; 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide; Norcycline; Bonomycin. Grade: >95%. CAS No. 808-26-4. Molecular formula: C21H22N2O7. Mole weight: 414.41. | |
| Sancycline hydrochloride | The hydrochloride salt of a rare semi-synthetic tetracycline. It is prepared by hydrogenolysis of the chloro and benzylic hydroxy moieties of declomycin. It inhibits protein translation by reversibly binding to the 30S ribosomal subunit and blocking the entry of aminoacyl tRNA into the ribosomal A site. It is a semi-synthetic antibiotic with activity against tetracycline-resistant E. coli, S. aureus and E. faecalis. Synonyms: 6-Demethyl-6-deoxytetracycline hydrochloride; NSC 51812; (4S,4aS,5aR,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1-11-dioxo-2-naphthacenecarboxamide Hydrochloride; Bonomycin; Norcycline; GS 2147; Minocycline EP Impurity B. Grade: >98% by HPLC. CAS No. 6625-20-3. Molecular formula: C21H23ClN2O7. Mole weight: 450.87. | |
| Sangivamycin | Sangivamycin is a nucleoside (purine) antibiotic produced by the strain of Str. rimosus BA-90912. 0.02-0.05 μg/mL of Sangivamycin inhibits HeLa cells. It has weak inhibitory effect on sarcoma-180 and adenocarcinoma 755 in mice. It has obvious inhibitory effect on leukemia L-1210. When intraperitoneally administered, the drug binds to nucleic acids in tissues in mice through phosphorylation. Uses: Antibiotics, antineoplastic. Synonyms: 4-Amino-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide; 7-Deazaadenosine-7-carboxamide; NSC 65346; Antibiotic B-14437; Ara-sangivamycin. Grade: 95%. CAS No. 18417-89-5. Molecular formula: C12H15N5O5. Mole weight: 309.28. | |
| Saquayamycin A1 | It is produced by the strain of Str. nodosus MH190-16F3. It has antimicrobial effect, but it has weaker effect against gram-negative bacteria. It has inhibitory effect on leukemia P388 cells and adriamycin-resistant P388 cells. Synonyms: Benz[a]anthracene-1,7,12(2H)-trione, 9-[2,6-dideoxy-4-O-[(2R,6S)-5,6-dihydro-6-methyl-5-oxo-2H-pyran-2-yl]- -Darabino-hexopyranosyl]-3,4,4a,12b-tetrahydro-3,4a,8,12b-tetrahydroxy-3-methyl-, (3R,4aR,12bS)-; (3R)-9-[4-O-[(2R,6S)-5,6-Dihydro-6-methyl-5-oxo-2H-pyran-2-yl]-2,6-dideoxy-β-D-arabino-hexopyranosyl]-3,4,4a,12b-tetrahydro-3α,4aα,8,12bα-tetrahydroxy-3-methylbenz[a]anthracene-1,7,12(2H)-trione. Grade: 95%. CAS No. 99260-66-9. Molecular formula: C31H32O12. Mole weight: 596.58. | |
| (Sar1)-Angiotensin II | (Sar1)-Angiotensin II is a specific agonist of angiotensin AT1 receptor. It binds to brain membrane-rich particles, with a Kd of 2.7 nM. (Sar1)-Angiotensin II can stimulate protein synthesis and cell growth in embryonic chick myocytes. Synonyms: 1-Sar-5-ile-angiotensin II; Angiotensin II, sarcosyl(1)-isoleucine(5)-. CAS No. 51833-69-3. Molecular formula: C49H71N13O10. Mole weight: 1002.17. | |
| (Sar1)-Angiotensin II acetate | (Sar1)-Angiotensin II acetate is a specific agonist of the angiotensin AT1 receptor that binds to brain membrane-rich particles, with a Kd of 2.7 nM. (Sar1)-Angiotensin II acetate can stimulate protein synthesis and cell growth in embryonic chick myocytes. Synonyms: H-Sar-Arg-Val-Tyr-Ile-His-Pro-Phe-OH.CH3CO2H; sarcosyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanine acetic acid. Grade: ≥95%. CAS No. 2863657-02-5. Molecular formula: C51H75N13O12. Mole weight: 1062.22. | |
| (Sar1,Ile4,8)-Angiotensin II | (Sar1,Ile4,8)-Angiotensin II activates extracellular signal-regulated kinases 1 and 2 (ERK1/2) through angiotensin II type 1A receptors. Its activation depends on the expression of β-arrestin 2. Synonyms: Sar-Arg-Val-Ile-Ile-His-Pro-Ile-OH; sarcosyl-L-arginyl-L-valyl-L-isoleucyl-L-isoleucyl-L-histidyl-L-prolyl-L-isoleucine; SII-Angiotensin II. Grade: ≥95%. CAS No. 185461-45-4. Molecular formula: C43H75N13O9. Mole weight: 918.14. | |
| [Sar1,Ile8]-Angiotensin II | It is a specific antagonist of angiotensin receptor, and it is also a peptide that has multiple effect on vascular smooth muscle. Synonyms: Sarilesin; H-Sar-Arg-Val-Tyr-Ile-His-Pro-Ile-OH; sarcosyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-isoleucine. Grade: ≥95%. CAS No. 37827-06-8. Molecular formula: C46H73N13O10. Mole weight: 968.15. | |
| SAR441255 | SAR441255 is a synthetic peptide agonist of the GLP-1, GCG, and GIP receptors. SAR441255 showed substantial body weight loss and improved glucose control in diabetic obese monkeys. Synonyms: H-Aib-HGTFTSDLSKL-K(γGlu-γGlu-Palm acid)-EEQRQ-AibEFIEWLKA-dAla-GPPS-Aib-KPPPK-NH2. Molecular formula: C206H323N51O66. Mole weight: 4570.06. | |
| [Sar9,Met(O2)11]-Substance P | A selective agonist of tachykinin NK1 receptor. Synonyms: H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Sar-Leu-Met(O2)-NH2; L-arginyl-L-prolyl-L-lysyl-L-prolyl-L-glutaminyl-L-glutaminyl-L-phenylalanyl-L-phenylalanyl-sarcosyl-L-leucyl-S,S-dioxo-L-methioninamide; (Sar(9))SP sulfone; 9-Sar-substance P sulfone; Sarcosyl(9)-substance P sulfone; 9-Sar-11-met(O2)-substance P; 9-Sarcosyl-11-methionine(O2)-substance P. Grade: ≥97% by HPLC. CAS No. 110880-55-2. Molecular formula: C64H100N18O15S. Mole weight: 1393.66. | |
| [Sar9] Substance P | A potent and selective neurokinin (NK)-1 receptor agonist. Synonyms: Substance P, 9-(N-methylglycine)-; H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Sar-Leu-Met-NH2; L-arginyl-L-prolyl-L-lysyl-L-prolyl-L-glutaminyl-L-glutaminyl-L-phenylalanyl-L-phenylalanyl-sarcosyl-L-leucyl-L-methioninamide. Grade: ≥95%. CAS No. 77128-75-7. Molecular formula: C64H100N18O13S. Mole weight: 1361.66. | |
| [Sar9] Substance P acetate | [Sar9]-Substance P acetate is a potent and selective neurokinin (NK)-1 receptor agonist. The effect of SP on progesterone metabolism was mimicked by the rNK1-specific agonist [Sar-9,Met(O2)11]-SP. Synonyms: Substance P, 9-(N-methylglycine)-, acetate (1:1); 9-(N-Methylglycine)substance P acetate; [MeGly9]-substance P acetate; H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Sar-Leu-Met-NH2.CH3CO2H; L-arginyl-L-prolyl-L-lysyl-L-prolyl-L-glutaminyl-L-glutaminyl-L-phenylalanyl-L-phenylalanyl-sarcosyl-L-leucyl-L-methioninamide acetate. Grade: ≥95%. Molecular formula: C66H104N18O15S. Mole weight: 1421.71. | |
| Sarafloxacin hydrochloride | Sarafloxacin is a quinolone antibiotic drug, inhibiting the topoisomerase II ligase domain. It inhibits bacterial Topo II α (DNA gyrase, topoisomerase) and is effective against Mycobacterium tuberculosis. Synonyms: Sarafloxacin HCl; A-56620; A 56620; A56620. Grade: >98%. CAS No. 91296-87-6. Molecular formula: C20H17F2N3O3.HCl. Mole weight: 421.83. | |
| Sarafotoxin S6c | Sarafotoxin S6c is a highly selective ETB endothelin receptor agonist (Ki = 0.29 and 28000 nM at ETB and ETA receptors, respectively). Uses: Vasoconstrictor agents. Synonyms: Sarafotoxin C; S6C; H-Cys-Thr-Cys-Asn-Asp-Met-Thr-Asp-Glu-Glu-Cys-Leu-Asn-Phe-Cys-His-Gln-Asp-Val-Ile-Trp-OH (Disulfide bridge: Cys1-Cys15, Cys3-Cys11); L-cysteinyl-L-threonyl-L-cysteinyl-L-asparagyl-L-alpha-aspartyl-L-methionyl-L-threonyl-L-alpha-aspartyl-L-alpha-glutamyl-L-alpha-glutamyl-L-cysteinyl-L-leucyl-L-asparagyl-L-phenylalanyl-L-cysteinyl-L-histidyl-L-glutaminyl-L-alpha-aspartyl-L-valyl-L-isoleucyl-L-tryptophan (1->15),(3->11)-bis(disulfide). Grade: ≥95% by HPLC. CAS No. 121695-87-2. Molecular formula: C103H147N27O37S5. Mole weight: 2515.75. | |
| Saralasin | Saralasin is a competitive and nonselective angiotensin II receptor antagonist. Uses: Angiotensin ii type 1 receptor blockers. Synonyms: (Sar1,Val5,Ala8)-Angiotensin II; Aralasin; Saralasinum. Grade: ≥97% by HPLC. CAS No. 34273-10-4. Molecular formula: C42H65N13O10. Mole weight: 912.04. | |
| Sarcosine | Sarcosine is an endogenous GlyT1 inhibitor. Sarcosine displays antipsychotic activity and has the potential to treat schizophrenia. Sarcosine has been shown to potentiate the action of glycine on the NMDA glycine binding site. Uses: Sarcosine, also known as n-methylglycine, is a naturally occurring amino acid derivative that has shown promise in various areas including drug discovery and development. in recent years, there has been growing interest in exploring the pharmacological properties of sarcosine and its derivatives due to their diverse biological activities. sarcosine is a basic derivative of amino acids that is ess. Synonyms: N-Methylglycine; Sarcosinic acid; Methylglycine; Glycine, N-methyl-. Grade: 98%. CAS No. 107-97-1. Molecular formula: C3H7NO2. Mole weight: 89.09. | |
| Sarecycline hydrochloride | Sarecycline hydrochloride is a novel, tetracycline-substituted, narrow-spectrum antibiotic compound used for the treatment of bacterial infections and neoplasms. It was approved by FDA for use as an orally once daily antibiotic treatment for patients suffering from moderate to severe acne vulgaris. It has anti-inflammatory activity and the potential for a favorable tolerability profile. Synonyms: P005672 HCl; P-005672 HCl; P 005672 HCl. CAS No. 1035979-44-2. Molecular formula: C24H30ClN3O8. Mole weight: 523.96. | |
| (S)-Atenolol-[d7] | (S)-Atenolol-[d7] is the labelled analogue of (S)-Atenolol, which is a selective β-adrenergic blocker and could be used as an antihypertensive agent. Synonyms: (S)-Atenolol-d7 (Iso-propyl-d7); 4-[(2S)-2-Hydroxy-3-[(1-methylethyl-d7)amino]propoxy]benzeneacetamide; (-)-Atenolol-d7; Esatenolol-d7; S-(-)-Atenolol-d7. Grade: 95% by HPLC; 98% atom D. CAS No. 1309283-20-2. Molecular formula: C14H15D7N2O3. Mole weight: 273.38. | |
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