USBiological 4 - Products
Worldwide
Our biochemicals, antibodies, recombinant proteins, cell culture media and molecular biology kits are used in virtually all scientific applications.From affordable research quantities to larger bulk amounts.
| Product | Description | |
|---|---|---|
| Q-VE-OPh (Negative Control) | Cell permeable, non-toxic negative control for the caspase inhibitor Q-VD-OPh. Stable in aqueous environment. Several folds less inhibitory activity than Q-VD-OPh. Perfect for both in vitro and in vivo studies. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C27H27F2N3O6. US Biological Life Sciences. |  Worldwide |
| (R)-(-)-2-Oxothiazolidine-4-carboxylic Acid | (R)-(-)-2-Oxothiazolidine-4-carboxylic Acid or Procysteine is a precursor to glutathione (GSH) which is an important antioxidant in plants, animals and fungi. Group: Biochemicals. Grades: Highly Purified. CAS No. 19771-63-2. Pack Sizes: 500mg, 1g. Molecular Formula: C4H5NO3S. US Biological Life Sciences. | Worldwide |
| (R) -3- (Phenyl ( (S) -1-phenylethyl) amino) butan-1-ol-d2 | (R) -3- (Phenyl ( (S) -1-phenylethyl) amino) butan-1-ol-d2 is intermediate of Maltol (M160130), an fragrance molecule used in flavor enhancers and fragrances. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500mg, 1g. Molecular Formula: C18H21D2NO. US Biological Life Sciences. | Worldwide |
| rac-Clopidogrel Carboxylic Acid | rac-Clopidogrel Carboxylic Acid is an metabolite of the drug Clopidogrel. Group: Biochemicals. Grades: Highly Purified. CAS No. 90055-55-3. Pack Sizes: 100mg, 500mg. Molecular Formula: C15H14ClNO2S. US Biological Life Sciences. | Worldwide |
| Rac Inhibitor III, EHop-016 | A cell-permeable NSC23766 analog that is more selective against Rac interaction with Vav2 (by 45% blockage at 4uM) than Tiam (35% blockage at 50uM) and ~100-times more potent than NSC23766 in suppressing Rac1-GTP level in MDA-MB-435 (IC50=1.1 vs. 95uM, respectively) cultures. Effectively inhibits PAK Thr423 phosphorylation (IC50 <2uM), while reducing Cdc42-GTP level only at higher concentrations (by 18% at 5uM), in MDA-MB-435 cultures.Rac Inhibitor III, EHop-016, CAS 1380432-32-5, is a cell-permeable analog of NSC23766. It is ~100-fold more potent than NSC23766 in suppressing Rac1-GTP level in MDA-MB-435 cells. Group: Biochemicals. Alternative Names: N?-(9-Ethyl-9H-carbazol-3-yl)-N²-(3-morpholin-4-yl-propyl)-pyrimidine-2,4-diamine. Grades: Highly Purified. CAS No. 1380432-32-5. Pack Sizes: 10mg. Molecular Formula: C??H??N?O. US Biological Life Sciences. | Worldwide |
| rac Quinacrine-d10 Dihydrochloride | Anthelmintic; antimalarial. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C23H20D10ClN3O 2(HCl). US Biological Life Sciences. | Worldwide |
| Ractopamine-10-O- β-glucuronide (Mixture of Diastereomers) | Ractopamine-10-O- β-glucuronide is a metabolite of Ractopamine (R071400); a β-adrenergic agonist and a repartitioning agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 166022-10-2. Pack Sizes: 1mg. Molecular Formula: C24H31NO9, Molecular Weight: 477.5. US Biological Life Sciences. | Worldwide |
| RAD51 Inhibitor, B02 ((E)-3-Benzyl-2-(2-(pyridin-3-yl)vinyl)quinazolin-4(3H)-one) | A cell-permeable pyridinylvinyl-quinazolinone compound that is shown to specifically inhibit human RAD51 (IC50=27.4uM). Does not affect RecA even at much higher concentration (~250uM). Directly interacts with RAD51 (=5.6uM), and disrupts its binding to DNA and nucleoprotein filament formation. Blocks double-strand break-induced homologous recombination and enhances sensitivity of cells to Cisplatin and Mitomycin C. Diminishes co-aggregate formation between RAD51-ssDNA filament and dsDNA. RAD51-Stimulatory Compound-1, RS-1 is also available. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| RAD51 Inhibitor, RI-1 | A cell-permeable 1H-Pyrrole-2,3-dione derivative that covalently binds to RAD51 at Cys319 and irreversibly destabilizes a protein-protein interface that is essential for filament formation and recombinase activity. Stimulates single strand annealing at a 5-30uM concentration. Inhibits subnuclear RAD51 foci formation following DNA damage without affecting replication protein A. Also, effectively sensitizes cancer cells to mitomycin C (~25uM) and generate synergistic cell kill in RAD51C mutant cells and with lesser effect on RAD51 complemented cells. Satisfies all four Lipinski rules for predicting drug likeness.CAS No:415713-60-9. Group: Biochemicals. Alternative Names: 3-chloro-1-(3,4-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione. Grades: Highly Purified. CAS No. 415713-60-9. Pack Sizes: 10mg. Molecular Formula: C??H??Cl?N?O?, Molecular Weight: 361.6. US Biological Life Sciences. | Worldwide |
| Rad6 Inhibitor (4-Amino-6-(phenylamino)-[1,3,5]triazin-2-yl)methyl-4-nitrobenzoate, (4-Amino-6-(phenylamino)-1,3,5-triazin-2-yl)methyl 4-nitrobenzoate, TZ9, TZ-9, TZ 9, HHR6 Inhibitor) | A cell-permeable triazine compound that directly targets human E2 Ubiquitin-conjugating enzyme Rad6B/HHR6B catalytic site via noncovalent interactions and effectively inhibits Rad6B-Ub thioester bond formation as well as subsequent substrate ubiquitination without affecting UbcH5B/UBE2D2-catalyzed BCA2 ubiquitination. Shown to inhibit the proliferation of high Rad6B-expressing MDA-MB-231 (IC50 = 6uM in 72h), but not the low Rad6B-expressing, non-transformed MCF10A, via G2/M arrest and apoptosis induction. Two known cellular Rad6 substrates, beta-catenin and PCNA, are reported to be downregulated following 24h inhibitor treatment in MDA-MB-231 cultures (0.5 to 5uM).CAS Number:002789-86-7. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?, Primary Target: Rad6B/HHR6B. US Biological Life Sciences. | Worldwide |
| RAGE Antagonist, FPS-ZM1 | A blood-brain-barrier-permeant, non-toxic, tertiary amide compound that acts as a high affinity, potent, multimodal blocker of RAGE (Receptor for Advanced Glycation End products) V domain-mediated ligand binding (Ki = 25, 148, and 230nM, respectively, against Ab40, HMGB1, and S100B, binding to sRAGE). Blocks RAGE-mediated influx of Ab40 and Ab42 into the brain. Also shown to suppress Ab-RAGE induced NF-kB activation and NF-kB-dependent transcription of b-secretase. Daily treatment of APPsw/0 murine AD model (1mg/kg/d via i.p.) is reported to greatly reduce Thioflavin S-positive amyloid plaques in cortex and hippocampus (by 70 to 80%) and restore congnitive performance to the level of non-AD mice.CAS No:945714-67-0. Group: Biochemicals. Grades: Highly Purified. CAS No. 945714-67-0. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Rapamycin | Rapamycin. Group: Molecular Biology. Grades: Highly Purified. CAS No. 53123-88-9. Pack Sizes: 25mg. Molecular Formula: C51H79NO13. US Biological Life Sciences. | Worldwide |
| Rapamycin-13C,d3 (contains d0) Technical Grade | Labelled Rapamycin. A triene macrolide antibiotic isolated from Streptomyces hygroscopicus. Name derived from the native word for Easter Island, RapaÂNui. Used as an immunosuppressant; antirestenotic. Group: Biochemicals. Grades: Purified. Pack Sizes: 1mg, 5mg. Molecular Formula: C5013CH76D3NO13, Molecular Weight: 918.18. US Biological Life Sciences. | Worldwide |
| Ras Superfamily GTPases GTP/GDP Binding Antagonist, CID 1067700 | A thiourea-derived small molecule that acts as a competitive inhibitor of nucleotide (BODIPY-GTP and BODIPY-GDP) binding by Rab7 (Ki=12.89-19.70nM). Equilibrates rapidly with Rab7 without affecting the rate of release of bound BODIPY-GTP or BODIPY-GDP. However, it exhibits a slightly lower potency against BODIPY-GDP bound Rab7 than BODIPY-GTP bound Rab7A. Acts by binding to the nucleotide binding pocket of Rab7. Also shown to inhibit nucleotide binding by mutant forms of Rab7 (Rab7Q67L and Rab7T22N) that are constitutively in the GTP and GDP bound states, with good potency. Also shown to block the nucleotide binding of several other Ras-related GTPases, but with reduced potency. Group: Biochemicals. Grades: Highly Purified. CAS No. 314042-01-8. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?S?, Primary Target: Rab7. US Biological Life Sciences. | Worldwide |
| (R)-CPPene ((R)-4-[(2E)-3-Phosphono-2-propenyl]-2-piperazinecarboxylic Acid, SDZ EAA 494, Midafotel) | A highly potent competitive antagonist of NMDA receptors (ED50 = 39 nM; pA2 = 6.8). Biologically active admitted systemically. Frequently used in assessing the functional roles of NMDA receptors mediated neurotransmissions in a variety of research areas, such as excitotoxic cell death, apoptosis, bipolar disorders, ischemia, traumatic brain injury, epilepsy, and neuropathic pain. Group: Biochemicals. Grades: Highly Purified. CAS No. 117414-74-1. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| (R)-CPP ((R)-3-(2-Carboxypiperazin-4-yl)propyl-1-phosphonic Acid) | A highly potent antagonist slightly selective for NR2A over other subtype nMDA receptors (Ki = 0.041, 0.27, 0.63 and 1.99uM for nMDA subtypes NR2A, NR2B, NR2C, and NR2D, respectively). Commonly used for various research in brain functions and disorders that neurotransmissions via nMDA receptors are involved. Group: Biochemicals. Grades: Highly Purified. CAS No. 126453-07-4. Pack Sizes: 10mg. Molecular Formula: C?H??N?O?P. US Biological Life Sciences. | Worldwide |
| Rebeccamycin (NSC 359079, BRN 4732638) | Antibiotic. Weak topoisomerase I (Topo I) inhibitor. Structurally similar to staurosporine. Does not show any inhibitory activity against protein kinases. Shows significant antitumor properties in vitro (IC50=480nM against mouse B16 melanoma cells and IC50=500nM against P388 leukemia cells). Group: Biochemicals. Grades: Highly Purified. CAS No. 93908-02-2. Pack Sizes: 250ug, 1mg. Molecular Formula: C??H??Cl?N?O?. US Biological Life Sciences. | Worldwide |
| Reboxetine Mesylate ( (2R*) -2- [ (R*) - (2-Ethoxyphenoxy) phenylmethyl] morpholine Methanesulfonate, Edronax, Vestra) | A potent and selective inhibitor of noradrenalin uptake (Ki values are 1.1, 129 and >10000nM for rat NET, SERT and DAT, respectively). Displays >1000-fold selectivity over alpha-adrenoceptors, 5-HT, dopamine and muscarinic ACh receptors. Orally active antidepressant. Group: Biochemicals. Grades: Highly Purified. CAS No. 71620-89-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Reductiomycin | Antibiotic, antibacterial, antifungal and antiviral. Antitumor compound. Group: Biochemicals. Grades: Highly Purified. CAS No. 68748-55-0. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Renin Inhibitor (Aliskiren Hemifumarate) | A non-peptide, direct renin inhibitor (IC50 = 0.6nM for human renin) and an anti-hypertensive agent. Aliskiren confers neuronal resistance to A beta toxicity in primary rat cortical cultures. Group: Biochemicals. Alternative Names: (2S,4S,5S,7S)-N-(2-Carbamoyl-2-methylpropyl)-5-amino-4-hydroxy-2,7-diisopropyl-8-[4-methoxy-3-(3-methoxypropoxy)phenyl]-octanamide Hemifumarate. Grades: Highly Purified. CAS No. 173334-58-2. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Resiquimod (R-848, S 28463) | Immune response modifier. Potent antitumor and antiviral compound. Stimulates antibody secretion and cytokine production. Used as adjuvant to increase the effectiveness of vaccines. Potent and selective synthetic ligand for Toll-like receptor 7 (TLR7) in mouse and for TLR7 and TLR8 in human. Activates immune cells via the TLR7/TLR8 MyD88-dependent signaling pathway and leads to the induction of NF-kappaB. NLRP3/NALP3 inflammasome activator, independent of TLRs and RIG-I. Upregulator of the opioid growth factor receptor. Used in the treatment of skin lesions such as herpes simplex virus. Group: Biochemicals. Alternative Names: 1-[4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol; 4-Amino-2- (ethoxymethyl) -1- (2-hydroxyisobutyl) imidazo[4, 5-c]quinoline; 4-Amino-2-ethoxymethyl-α,α-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol; R 848; Resiquimod; S 28463. Grades: Highly Purified. CAS No. 144875-48-9. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C??H??N?O?, Molecular Weight: 314.4. US Biological Life Sciences. | Worldwide |
| Resistomycin (Geliomycin, Heliomycin, Itamycin, 3,5,7,10-Tetrahydroxy-1,1,9-trimethyl-1H-benzo-[cd]pyrene-2,6-dione) | Antibacterial (Gram-positive and mycobacteria). RNA polymerase inhibitor. Apoptosis inducer. Group: Biochemicals. Grades: Highly Purified. CAS No. 20004-62-0. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Reticulol | Antibiotic. Cyclic adenosine 3',5'-monophosphate phosphodiesterase and topoisomerase I (Topo I) inhibitor. Antitumor compound. Group: Biochemicals. Alternative Names: 6,8-Dihydroxy-7-methoxy-3-methyl-1H-2-benzopyran-1-one; 6,8-Dihydroxy-7-methoxy-3-methylisocoumarin; K 251-1; NSC 294978; Reticulol; 6,8-Dihydroxy-7-methoxy-3-methyl-isocoumarin. Grades: Highly Purified. CAS No. 26246-41-3. Pack Sizes: 250ug, 1mg. Molecular Formula: C??H??O?. US Biological Life Sciences. | Worldwide |
| REV-ERB Agonist II, SR9009 | A pyrrolidinecarbamate compound that acts as a specific REV-ERB-alpha/beta agonist. Exhibits a direct and reversible binding (Kd = 800nM REV-ERB-alpha) and shows excellent selectivity over a panel of 46 other nuclear receptors. Potently increases REV-ERB-dependent repressor activity (IC50 = 670 and 800nM in Gal4-REV-ERB-alpha and beta transfected HEK 293 cells) and reduces BMAL1 mRNA in HepG2 cells (IC50 = 710nM). Shown to cross the blood-brain barrier and exhibit desirable pharmacokinetic properties. A 7-day administration of SR9009 (100mg/kg, i.p., b.i.d.) causes a significant weight and fat loss in C57BL6 mice with concomitant reduction in plasma glucose and free fatty acid levels, and alters circadian pattern. 217739, CAS # 1379686-30-2, acts as a specific REV-ERB-α/ β agonist that exhibits a direct and reversible binding (Kd = 800nM). Group: Biochemicals. Grades: Highly Purified. CAS No. 1379686-30-2. Pack Sizes: 25mg. Molecular Formula: C??H??ClN?O?S. US Biological Life Sciences. | Worldwide |
| RGS Proteins Inhibitor II, CCG-50014 (4-(4-Fluorobenzyl)-2-p-tolyl-1,2,4-thiadiazolidine-3,5-dione) | A cell-permeable thiadiazolidinedione compound that acts as a direct, potent, selective and cysteine-reactive irreversible inhibitor of RGS4 over other RGS proteins (IC50=0.03, 0.12, 3.5, 11, >200 and >200uM against RGS4, RGS19, RGS16, RGS8, RGS7 and RGS4Cys- using FCPIA assay, respectively). Shown to block RGS4-Ga0 interaction and repress Ga0-dependent membrane localization of RGS4 in HEK-293T cells with no effect on the intrinsic rate of GTP hydrolysis by Ga0. Suggested to interact with Cys107-RGS8 allosteric regulatory site and display minimal affinity towards papain (IC50>100uM). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Rhapontigenin | A natural analog of resveratrol with antioxidant and anti-cancer activity. Rhapontigenin was found to scavenge intracellular reactive oxygen species (ROS), the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical, and hydrogen peroxide (H2O2). Rhapontigenin protected against H2O2-induced membrane lipid peroxidation and cellular DNA damage, which are the main targets of oxidative stress-induced cellular damage. Group: Biochemicals. Alternative Names: 5-[(1E)-2-(3-?hydroxy-4-methoxyphenyl)ethenyl]-1,?3-benzenediol. Grades: Highly Purified. CAS No. 500-65-2. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Rhodamine B | Rhodamine B is used in biological studies for an anti-reactive oxygen species/hepatic fibrosis drug delivery system based on salvianolic acid B loaded mesoporous silica nanoparticles. Group: Biochemicals. Grades: Highly Purified. CAS No. 81-88-9. Pack Sizes: 100g, 250g. Molecular Formula: C28H31ClN2O3. US Biological Life Sciences. | Worldwide |
| Rho Inhibitor, Rhosin ( (2R) -2-Amino-3- (1H-indol-3-yl) -N'- ( (1E) -quinoxalin-6-ylmethylidene) propanehydrazide, G04) | A cell-permeable (quinoxalinyl methyl idene-D-Tryptophanyl) hydrazide that directly targets Rho GEF binding domain (Kd = 354nM for RhoA), thereby prevents Rho from interacting with its GEFs (including LARG, DBL, LBC, p115 RhoGEF, and PDZ RhoGEF), but not p190RhoGAP, RhoGDI, or its effectors (ROCK, mDia, PKN, Rhoteckin). Shown to inhibit serum-induced RhoA, RhoB, and RhoC, but not Cdc42 or Rac1, activation, MLC & PAK phosphorylation, as well as stress fiber & focal complex formation in serum-starved NIH3T3 cultures (Effective conc. 30uM) in a reversible manner. Group: Biochemicals. Grades: Highly Purified. CAS No. 1173671-63-0. Pack Sizes: 25mg. Molecular Formula: C??H??N?O, Primary Target: Rho GTPase. US Biological Life Sciences. | Worldwide |
| Rho Kinase Inhibitor XIII, RKI-1447 (1-(3-Hydroxybenzyl)-3-(4-(pyridin-4-yl)thiazol-2-yl)urea, Mesylate, 1-(3-Hydroxybenzyl)-3-(4-(pyridin-4-yl)thiazol-2-yl)urea, Methanesulfonate, ROCK Inhibitor XIII) | A cell-permeable pyridylthiazolyl-urea that acts as a potent, ATP site-targeting, Rho Kinase inhibitor (IC50 = 14.5 and 6.2nM against ROCK1 and ROCK2, respectively), displaying much reduced potency against PKA, PKN1/PRK1, p70S6K/RPS6kB1, AKT1, MRCKa/CDC42BPA (85.5%, 80.5%, 61.9%, 56%, and 50.4% inhibition, respectively, by 1uM RKI-1447) or 15 other kinases. Selectively inhibits ROCK-dependent, but not mTORC2-dependent, cellular phosphorylations (effective conc. 0.1-1uM in MDA-MB-231, MDA-MB-468, and H1299 cultures). Shown to be efficacious in suppressing established tumor expansion in a murine ErbB2 mammary cancer model (200mg/kg/day i.p.) in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?S; CH?SO?H. US Biological Life Sciences. | Worldwide |
| Rho/SRF Pathway Inhibitor, CCG-1423 (N- (2- (4-Chloroanilino) -1-methyl-2-oxoethoxy) -3, 5-bis (trifluoromethyl) benzamide) | A cell-permeable benzamide compound that acts as an effective inhibitor against RhoA- and RhoC-mediated cellular activities by targeting signaling events downstream of Ga12/13 and RhoA/C, affecting MKL recruitment and/or postrecruitment function of MKL1, but not SRF-SRE interaction or ROCK kinase activity. CCG-1423 is shown to inhibit RhoC-dependent cell growth in A375M2 and SK-Mel-147 (IC50≤300nM) and block RhoC/ Ga12-mediated PC-13 invasion in Matrigel assays (by ~90% at 3uM). Group: Biochemicals. Grades: Highly Purified. CAS No. 285986-88-1. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| (R)-Ketamine-d6 Hydrochloride | (R)-Ketamine-d6 is labelled (R)-Ketamine (K165305, HCl salt) which is the less active enantiomer of the NMDA receptor antagonist and anesthetic agent Ketamine (K165300). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C13H11D6Cl2NO, Molecular Weight: 280.22. US Biological Life Sciences. | Worldwide |
| Ro 20-1724 (4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone) | A cell-permeable, selective inhibitor of cAMP-specific phosphodiesterase (PDE IV; IC50=2uM). Inhibits superoxide generation and arachidonic-induced platelet aggregation. Also inhibits fMLP-induced neutrophil adhesion to vascular endothelial cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 29925-17-5. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Rolipram (4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone) | A cell-permeable, selective inhibitor of cAMP-specific phosphodiesterase (PDE IV; IC50=800nM). A rolipram-insensitive PDE IV subtype is also known to exist. Also inhibits NF-kB and NFAT activation in Jurkat and primary T cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 61413-54-5. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Roquefortine C (NSC292134) | Potent neurotoxin. Mycotoxin. Tremorgenic. Gram-positive bacteria growth inhibitor. Cytochrome p450 inhibitor. Lymphocyte proliferation inhibitor. Cytotoxic. Group: Biochemicals. Grades: Highly Purified. CAS No. 58735-64-1. Pack Sizes: 500ug, 1mg. US Biological Life Sciences. | Worldwide |
| ROR-alpha/gamma Agonist | A cell-permeable diaryl amide derived from T1317 (a known LXR agonist and retinoic acid receptor (ROR) inverse agonist) that acts as a highly selective agonist of RORalpha/gamma and does not exhibit affinity for FXR, LXRa and LXRb. Shown to stabilize p53 in cancer cells and increase the expression of p21 and PUMA. Induces apoptosis in hepatocellular carcinoma (HepG2) cells in a RORa and p53-dependent process. Also reported to increase the expression of Sox4 and REV-ERBa in HepG2 cells. Exhibits suitable pharmacokinetic properties with sustained plasma levels even after 8 hours following a single i.p. injection. Exposure to SR1078 Induces expression of glucose-6-phosphatase and fibroblast growth factor 21 in murine models (10mg/kg/i.p.). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| RORg Inverse Agonist, SR2211 (1,1,1,3,3,3-hexafluoro-2-(2-fluoro-4'-((4-(pyridin-4-ylmethyl)piperazin-1-yl)methyl)-[1,1'-biphenyl]-4-yl)propan-2-ol, SR-2211, SR 2211) | A cell-permeable, piperazine containing biphenyl compound that binds directly to retinoic acid receptor related orphan receptor g (RORg) and acts as a highly selective and inverse agonist (Ki =105nM; IC50 ~320nM). Reported to block the transcriptional activity of RORg and suppress the synthesis of IL-17 in EL-4 murine lymphoma cell line. Exhibits only a minimal effect on RORa and LXRa activity.CAS Number:1359164-11-6. Group: Biochemicals. Grades: Highly Purified. CAS No. 1359164-11-6. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Rotigotine Hydrochloride ((6S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol Hydrochloride, Dopamine Receptor Agonist, Rotigotine Hydrochloride, Neupro) | A highly potent non-ergoline dopamine D2 and D3 receptor agonist (Ki = 13 and 0.71nM for D2 and D3 respectively). Also displays significant affinity for 5-HT1A and adrenergic alpha2B receptors. Transdermally used in treatment of Parkinson's disease and restless legs syndrome. Group: Biochemicals. Grades: Highly Purified. CAS No. 125572-93-2. Pack Sizes: 10mg. Molecular Formula: C??H??NOS HCl. US Biological Life Sciences. | Worldwide |
| (R)-Perharidine 1 | Potent and selective inhibitor of cyclin dependent kinases CDK1, CDK2, CDK5 and CDK9. Apoptosis inducer. Inhibits the proliferation of various cancer cell lines. Casein kinase 1 (CK1delta/epsilon) inhibitor. Potential anti-inflammatory compound. Potential antidiabetic compound. Group: Biochemicals. Grades: Highly Purified. CAS No. 1133437-80-5. Pack Sizes: 1mg, 5mg, 25mg. US Biological Life Sciences. | Worldwide |
| [R- (R*, R*) ]- (1, 2-Dihydroxypropyl) phosphonic Acid | P-[(1R,2R)-1,2-Dihydroxypropyl]-phosphonic Acid (Fosfomycin EP Impurity A) is a Fosfomycin (F727500) impurity. Fosfomycin is an antibiotic that exerts a broad spectrum of antibacterial activity. P-[(1R,2R)-1,2-Dihydroxypropyl]-phosphonic Acid is an intermediate in the synthesis of [2- [2-Amino-3-hydroxy-2- (hydroxymethyl) propoxy] -1-hydroxypropyl] phosphonic Acid (A611565), another Fosfomycin (F727500) impurity. Group: Biochemicals. Grades: Highly Purified. CAS No. 132125-60-1. Pack Sizes: 25mg, 50mg. Molecular Formula: C3H9O5P. US Biological Life Sciences. | Worldwide |
| RS 102895 Hydrochloride (1-[2-[4- (Trifluoromethyl) phenyl]ethyl]-spiro[4H-3, 1-benzoxazine-4, 4-piperidin]-2 (1H) -one Hydrochloride, RS 102895, RS102895) | A selective antagonist for CCR2 receptors (IC50 = 0.36 and 17.8uM for CCR2b and CCR1 receptors, respectively). Blocks monocyte chemoattractant protein-1 induced calcium influx and chemotaxis (IC50 = 32nM and 1.7uM respectively). A potential anti-inflammatory therapeutic agent by Inhibiting alpha1A, alpha1D and 5-HT1A receptors. Group: Biochemicals. Grades: Highly Purified. CAS No. 300815-41-2. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| RS 127445 Hydrochloride | A selective, high affinity , orally bioavailable 5-HT2B receptor antagonist. RS-127445 was found to have nanomolar affinity for the 5-HT2B receptor (pKi = 9.5) and 1,000 fold selectivity for this receptor as compared to numerous other receptor and ion channel binding sites including the closely related 5-HT2A and 5-HT2C receptors. In isolated human cells, RS-127445 exbhited an IC50 greater than 10uM. Group: Biochemicals. Grades: Highly Purified. CAS No. 199864-86-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| (R)-Semivioxanthin | Mycotoxin. Antibacterial (Gram-positive) and antifungal. Immunoregulator by degradation of IkappaB (Inhibitor of NF-kappaB) and regulation of the TNF-alpha (tumor necrosis factor-alpha) and MAPK (mitogen-activated protein kinase) signaling pathways. Group: Biochemicals. Alternative Names: (3R)-3,4-Dihydro-9,10-dihydroxy-7-methoxy-3-methyl-1H-naphtho[2,3-c]pyran-1-one; (+)-Semi-vioxanthin; (R)-semi-Vioxanthin; Semivioxanthin. Grades: Highly Purified. CAS No. 70477-26-8. Pack Sizes: 500ug, 1mg. Molecular Formula: C??H??O?. US Biological Life Sciences. | Worldwide |
| (R)-Semixanthomegnin | Antibacterial mycotoxin derivative. Monomer (half) of the genotoxic mycotoxin xanthomegnin. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C15H12O6. US Biological Life Sciences. | Worldwide |
| RSK2 Inhibitor, RMM-46 ((E)-2-Cyano-N-(1-hydroxy-2-methylpropan-2-yl)-3-(3-(3,4,5-trimethoxyphenyl)-1H-indazol-5-yl)acrylamide, RMM46, RSK Inhibitor IV) | A cell-permeable cyanoacrylamide compound that acts as a potent, reversible, and selective inhibitor of ribosomal S6 kinase 2 (RSK2; IC50 = 12 and 2.5nM for wild-type and T493M RSK2, respectively). Shown to act by covalently modifying Cys436 at the ATP-binding site. Exhibits good selectivity over NEK2 and PLK1 (IC50 = 530nM and 2.2uM) and does not affect the activity of a panel of 26 other protein kinases. Also shown to block phosphorylation of mitogen and stress activated kinases (MSK) 1, 2, and 3 in PMA-stimulated COS7 cells (IC50 ~100nM) and CREB phosphorylation in PMA- or UV-stimulated HeLa cells (IC50 ~300nM). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?. US Biological Life Sciences. | Worldwide |
| (R)-(+)-SKF38393 Hydrochloride (Dopamine D1/D5 Receptor Partial Agonist, (R)-SKF-38393 Hydrochloride, SKF-38393, SKF38393, SKF 38393) | A benzazepine derivative that acts as a selective Dopamine D1/D5 receptor partial agonist. Examination of the isomers in several in vitro and in vivo tests for both central and peripheral dopaminergic activity revealed that activity resided almost exclusively in the R isomer. The results suggest that the properly oriented 1-phenyl substituent of 1 is important for dopamine-like activity. Reported to have stimulant and anorectic effects. Group: Biochemicals. Grades: Highly Purified. CAS No. 81702-42-3. Pack Sizes: 5mg. Molecular Formula: C16H??NO? HCl. US Biological Life Sciences. | Worldwide |
| (RS)-PPG (RS) -4-Phosphonophenyl glycine) | A potent and subtype-selective agonist for group III metabotropic glutamate receptors. 25-fold higher selectivity for mGlu8 (EC50 =0.21uM ) than for other group III mGlu receptors (EC50 = 5.2, 4.7, and 185uM for mGlu4,6,7, respectively). Widely used as anticonvulsant, antidepressant, anxiolytic, and neuroprotective agent in research. Group: Biochemicals. Grades: Highly Purified. CAS No. 120667-15-4. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Rubiginone D2 ((2S,3S,4R)-2,4-Dihydroxy-8-methoxy-3-methyl-3,4-dihydrotetraphene-1,7,12(2H)-trione) | Antibiotic. Antibacterial. Antitumor compound. Group: Biochemicals. Grades: Highly Purified. CAS No. 274913-71-2. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Rubratoxin A | Mycotoxin. Potent and selective competitive protein phosphatase 2A (PP2A) inhibitor. Does not inhibit PP1, PP2B, PTP1B, ALP and CIP. Antitumor agent. Antimetastatic. Group: Biochemicals. Alternative Names: BRN 1633008; HSDB 3532, (4S,5R,10R)-rel-10-[(R)-[(2R)-3,6-dihydro-6-oxo-2H-pyran-2-yl]hydroxymethyl]-4,5,8,9,10,11-hexahydro-4,8-dihydroxy-5-[(1S)-1-hydroxyheptyl]-1H-cyclonona[1,2-c:5,6-c']difuran-1,3,6-trione. Grades: Highly Purified. CAS No. 22467-31-8. Pack Sizes: 250ug, 500ug. Molecular Formula: C??H??O??. US Biological Life Sciences. | Worldwide |
| Rubrofusarin (NSC 258316) | Monomer of aurofusarin. Mycotoxin. Anticancer and antimycobacterial compound in vivo. Moderate tyrosinase inhibitor. Anti-estrogenic. Group: Biochemicals. Grades: Highly Purified. CAS No. 3567-00-8. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| Rubromycin Beta (Methyl-8,10'-dihydroxy-5,7-dimethoxy-4,9,9'-trioxo-4,4',9,9'-tetrahydro-3H,3'H-spiro[naphtho[2,3-b]furan-2,2'-pyrano[4,3-g]chromene]-7'-carboxylate) | Antibiotic. HIV-1 reverse transcriptase inhibitor. Human telomerase inhibitor. Cytostatic against different tumor cell lines. Group: Biochemicals. Grades: Highly Purified. CAS No. 27267-70-5. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| Rubromycin Gamma | Antibiotic. HIV-1 reverse transcriptase and human telomerase inhibitor. Antibacterial. Cytostatically active against different tumor cell lines. Group: Biochemicals. Grades: Highly Purified. CAS No. 27267-71-6. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| Ruxolitinib-azide | Ruxolitinib-azide is a derivative of Ruxolitinib (R702000), which is a selective Janus tyrosine kinase (JAK1 and JAK2) inhibitor used in the treatment of myeloproliferative neoplasms and psoriasis. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C17H20N8, Molecular Weight: 336.39. US Biological Life Sciences. | Worldwide |
| RXFP1 Agonist (2-Isopropoxy-N- (2- (3- (trifluoro methyl sulfonyl) phenylcarbamoyl) phenyl) benzamide, LGR7 Agonist, Relaxin/Insulin-like Family Peptide Receptor 1 Agonist, Leucine-Rich Repeat-Containing GPCR 7 Agonist) | A cell-permeable 2-acetamido-N-phenylbenzamide that selectively activates human, but not mouse, LGR7/RXFP1-mediated cAMP induction (EC50 = 200nM in THP1) via allosteric interaction with the ECL3 region without competing against ECL2-mediated relaxin binding or affecting AVPR1B- or LGR8/RXFP2-mediated cAMP induction. Although shown to be ~150-fold and 500-fold less potent than relaxin (RLX), respectively, in VEGF mRNA induction and cellular impedance assays, pharmacokinetic studies reveal superior in vivo stability to RLX and in vivo bioavailability in mice via oral (Cmax/Tmax = 604nM/plasma/1h and 1026ng/g heart/1.5h; 30mg/kg) or intraperitoneal (Cmax/Tmax = 9.29uM/plasma/1h and 28.6uMol/kg heart/1h; 30mg/kg) administration with good aqueous solubility (7uM in PBS). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| RyR-Calstabin Interaction Stabilizer, S107 (7-methoxy-4-methyl-2, 3, 4, 5-tetrahydrobenzo[f][1, 4]thiazepine, Ryanodine Receptor Stabilizer; Rycal S107) | A cell-permeable, orally active benzothiazepine that effectively blocks leaky intracellular calcium release by preventing the dissociation/depletion of calstabin from the ryanodine receptor (RyR) complex due to receptor modifications, such as oxidation, S-nitrosylation, hyperphosphorylation, or mutation (complete blockage of 1 mM tetracaine-induced leakage in murine RyR2 S2808D+/+ myocytes at 1uM). Shown to prevent stress-induced cognitive dysfunction by stabilizing RyR2-calstabin-2 (FKBP12.6) interaction in brain (75mg/kg/day; p.o.) and maintain exercise capacity by stabilizing RyR1-calstabin-1 (FKBP12) interaction in skeletal muscle (2. 5ug/0. 25uL/h/animal; s.c) in mice, as well as restore normal cardiac function (20mg/kg/day; s.c) in mice with R2474S or S2808D RyR2 mutation in vivo.Primary Target:RyR2. Group: Biochemicals. Alternative Names: 7-methoxy-4-methyl-2, 3, 4, 5-tetrahydrobenzo[f][1, 4]thiazepine, Ryanodine Receptor Stabilizer; Rycal S107. Grades: Highly Purified. CAS No. 927871-76-9. Pack Sizes: 10mg. Molecular Formula: C??H??NOS, Molecular Weight: 209.3. US Biological Life Sciences. | Worldwide |
| S18986 ((S)-2,3-dihydro-[3,4]cyclopentano-1,2,4-benzothiadiazine-1,1-dioxide, (S)-2,3,3a,4-tetrahydro-1H-benzo[e]pyrrolo[2,1-c][1,2,4]thiadiazine 5,5-dioxide, AMPA Receptor Positive Allosteric Modulator, S18986) | A positive allosteric modulator selective for the AMPA receptors. A nootropic and neuroprotective agents frequently used in researches studying cognition, memory, and aging related cognitive declines. Induces production of BNDF and AMPA-mediated release of noradrenaline and acetylcholine. Biologically viable admitted systematically. Group: Biochemicals. Grades: Highly Purified. CAS No. 175340-20-2. Pack Sizes: 5mg. Molecular Formula: C??H??N?O?S. US Biological Life Sciences. | Worldwide |
| S1P4 Receptor Antagonist (CYM50358) | An arylcarboxamide that acts as a potent and selective sphingosine-1-phosphate receptor 4 (S1P4) antagonist (IC50=25nM), among a panel of five S1P receptors. It is shown to inhibit other S1P isoforms only at much higher concentrations (IC50 = 6.4uM, 3.9uM, 5.5uM, and 25uM for S1P1, S1P2, S1P5, and S1P3 (95% inhibition), respectively). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| S 24795 (alpha 7 Nicotinic Acetylcholine Receptor Agonist, S 24795, 2-(2-(4-bromophenyl)-2-oxoethyl)-1-methylpyridin-1-ium Iodide, alpha 7 nAChR Agonist, S 24795, S-24795, S24795) | A potent partial agonist selective for alpha7 nAChRs (EC50 = 34uM). Widely used in investigating the roles of alpha7 nAChRs in aging, learning and memory, and cognition. Enhances memory in mouse models for Alzheimer's disease. Group: Biochemicals. Grades: Highly Purified. CAS No. 304679-75-2. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| S6K1 Inhibitor II, DG2 (3-Bromo-4- (4- (2-methoxyphenyl) piperazin-1-yl) -1H-pyrazolo[3, 4-d]-pyrimidine) | A cell-permeable pyrazolopyrimidine compound that acts as a potent, ATP-competitive and reversible inhibitor of S6K1 (p70 ribosomal protein S6 kinase 1; IC50=9.1nM) with ~2,400 reduced activity towards Akt (IC50=22uM). Shown to completely block rpS6-Ser240/244 phosphorylation in L6 cells at 2.5uM without inducing pAkt-Thr308 and Ser473, and display substantial selectivity in a 219-kinase panel (1uM of DG2 in the presence of 10uM of ATP; IC50 ≥50%; Clk1, Clk2, Dyrk1A, Dyrk3, Flt3, Flt3-D835Y, Flt4, GSK-3a/b, R, MAP4K4, Mink1, PKA, PRKG1, PRKG2, Ret-V804L, Ret-Y791F, RSK1, RSK3, RSK2, MSK2, MSK1 and p70S6K). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| S6K1 Inhibitor, PF-4708671 ((2-((4-(5-Ethylpyrimidin-4-yl)piperazin-1-yl)methyl)-5-(trifluoromethyl)-1H-benzo[d]imidazole, p70 Ribosomal S6 Kinase 1 Inhibitor) | A cell-permeable piperazinyl-pyrimidine compound that acts as an inhibitor against S6K1 (Ki=20nM; IC50=160nM) and MSK1 (IC50=950nM) kinase activity, exhibiting little or much reduced potency against 85 other protein and lipid kinases ( IC50=4.7, 9.2, 65uM, respectively, against RSK1, RSK2, and S6K2; <27% inhibition of the rest at 1uM). Shown to selectively inhibit IGF1- and PMA-stimulated S6K1 substrates phosphorylation in HEK-293 cells in a dose-dependent manner (up to 10uM) in vitro and alleviate heart remodeling and functional damage in a MI (myocardial infarction) model in mice in vivo (75/mg/kg/daily i.p.). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??F?N?, Molecular Weight: 390.4. US Biological Life Sciences. | Worldwide |
| Safrole | Safrole, is an oily liquid typically extracted from the root-bark or the fruit of sassafras plants in the form of sassafras oil. It is a precursor in the synthesis of the insecticide synergist piperonyl butoxide and the empathogenic / entactogenic drug MDMA (M303985). Group: Biochemicals. Grades: Highly Purified. CAS No. 94-59-7. Pack Sizes: 10mg, 25 mg. Molecular Formula: C10H10O2. US Biological Life Sciences. | Worldwide |
| SAG Analog (cis-isomer) (Compound 10b, 3, 4-Dichloro-N- (cis-4- (methylamino) cyclohexyl) -N- (3-pyridin-4-ylbenzyl) benzo[b]thiophene-2-carboxamide) | A cell-permeable, highly active, Sonic hedgehog (Shh) signaling agonist. Smoothened (Smo) agonist. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. US Biological Life Sciences. | Worldwide |
| SAG Analog (trans-isomer) (Compound 10c, 3, 4-Dichloro-N- (trans-4- (methylamino) cyclohexyl) -N- (3-pyridin-4-ylbenzyl) benzo[b]thiophene-2-carboxamide) | A cell-permeable, low toxicity, Sonic hedgehog (Shh) signaling agonist. Smoothened (Smo) agonist. Also acts as a potent activator of VEGF expression in vitro. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug , 1mg. US Biological Life Sciences. | Worldwide |
| SAG Dihydrochloride (Water Soluble) (N-Methyl-N?- (3-pyridinylbenzyl) -N?- (3-chlorobenzo [b]thiophene-2-carbonyl) -1, 4-diaminocyclohexane. 2HCl) | Cell permeable Sonic hedgehog (Shh) agonist. Cell permeable smoothened (Smo) agonist. Induces Sonic hedgehog (Shh) pathway activation and counteracts cyclopamine inhibition of Smo. Acts as an activator of Smo at low concentrations and as an inhibitor of Smo at very high concentrations. Potent activator of VEGF expression in vitro. Group: Biochemicals. Grades: Highly Purified. CAS No. 364590-63-6. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| Salbutamol Hemisulfate (a-([t-Butylamino]methyl)-4-hydroxy-m-xylene-a,a-diol, Albuterol, b-Adrenoceptor Agonist, Salbutamol Hemisulfate) | A potent and selective beta-2-adrenoceptor agonist (EC50 = 5.3nM) that displays bronchodilator actions. Unlike other beta-2- adrenoceptor agonists, Salmeterol binds to exo-site domain of beta-2-AR receptors, producing a slow onset of action and prolonged activation. Clinically used for the treatment of asthma and chronic obstructive pulmonary disease (COPD). Group: Biochemicals. Grades: Highly Purified. CAS No. 51022-70-9. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Salinomycin, Sodium Salt | Cancer stems cells (CSCs) are a subpopulation of cells within tumors that drive tumor growth and recurrence. They are resistant to many current cancer treatments. Salinomycin (sodium salt) is an antibacterial and coccidiostat compound that shows selective toxicity for the CSCs that exist as a subpopulation within HMLER breast cancer cells (IC50s = ~24 versus ~90uM).1 At 8uM, salinomycin treatment of 4T1 and MCF7Ras breast cancer cell lines results in a ~2-fold and ~3-fold, respective reduction of CSCs relative to controls.1 Treatment of 5mg/kg salinomycin in mice implanted with SUM159 human breast cancer cells inhibits mammary tumor growth and induces increased epithelial differentiation of tumor cells. Group: Biochemicals. Alternative Names: alpha-ethyl-6?[5-[2-(5-?ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)-15-hydroxy-2,?10, 12-trimethyl-1, 6, 8-trioxadispiro[4. 1. 5. 3]pentadec-13-en-9-yl]-2-?hydroxy-1, ?3-dimethyl-4- oxoheptyl]tetrahydro-5-methyl-2H-pyran-2-acetic acid,? monosodium salt. Grades: Highly Purified. CAS No. 55721-31-8. Pack Sizes: 5mg, 10mg, 50mg. Molecular Formula: C42H69O11 Na, Molecular Weight: 773. US Biological Life Sciences. | Worldwide |
| Salinosporamide A | Potent, irreversible inhibitor of all the 3 proteolytic activities of the mammalian 20S proteasome. Group: Biochemicals. Alternative Names: SalA; Marizomib; NPI-0052. Grades: Highly Purified. CAS No. 437742-34-2. Pack Sizes: 100ug. US Biological Life Sciences. | Worldwide |
| Salmeterol Xinafoate ((±) 4-Hydroxy-a1-[[[6- (4-phenylbutoxy) hexyl]amino]m-ethyl]-1, 3-benzenedimethanol Xinafoate, GR 33343X Xinafoate, b2-Adrenoceptor Agonist, Salmeterol Xinafoate) | A potent and selective beta-2-adrenoceptor agonist (EC50 = 5.3nM) that displays bronchodilator actions. Unlike other beta-2- adrenoceptor agonists, Salmeterol binds to exo-site domain of beta-2-AR receptors, producing a slow onset of action and prolonged activation. Clinically used for the treatment of asthma and chronic obstructive pulmonary disease (COPD). Group: Biochemicals. Grades: Highly Purified. CAS No. 94749-08-3. Pack Sizes: 10mg. Molecular Formula: C??H??NO?; C??H?O?. US Biological Life Sciences. | Worldwide |
| Salvinorin A (kappa-opioid Receptor Agonist, Salvinorin A, Divinorin A) | A highly potent and selective non-alkaloid positive allosteric modulator of Kappa-opioid receptors (Ki = 4.3nM and 16nM for native and cloned kappa-opioid receptors, respectively). Also acts as a D2DR partial agonist (Ki = 5-10nM). Used in studies of addition. Group: Biochemicals. Grades: Highly Purified. CAS No. 83729-01-5. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Saquayamycin B1 | Angucycline antibiotic. Antibacterial. Antitumor compound. Active against Gram-positive bacteria and P388 leukemia cells. Farnesyl-protein transferase inhibitor. Inhibitor of nitric oxide synthase (NOS) (shown for Saquayamycin A1). Group: Biochemicals. Alternative Names: 9- (2, 9-dimethyl-3-oxo-4, 4a, 5a, 6, 7, 9, 9a, 10a-octahydrodipyrano [4, 2-a: 4', 3'-e] [1, 4]dioxin-7-yl) -3, 4a, 8, 12b-tetrahydroxy-3-methyl-2, 4-dihydrobenzo [a]anthracene-1, 7, 12-trione. Grades: Highly Purified. CAS No. 99260-68-1. Pack Sizes: 500ug, 1mg. US Biological Life Sciences. | Worldwide |
| Sarcophine (NSC250434) | Acetylcholine esterase and ATPase inhibitor. Ichthyotoxin. Tumorigenesis and JB6 cell trans- formation inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 55038-27-2. Pack Sizes: 2mg, 10mg. US Biological Life Sciences. | Worldwide |
Would you like to list your products on USA Chemical Suppliers?
Our database is helping our users find suppliers everyday.