BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Angiotensin II 5-valine TFA | Angiotensin II 5-valine is an agonist of angiotensin receptor. Synonyms: Valine angiotensin II TFA; 5-L-Valine angiotensin II TFA. Molecular formula: C51H70F3N13O14. Mole weight: 1146.18. |  |
| Angiotensin IV | Cas No. 23025-68-5. | |
| Anguizole | Anguizole is a small molecule inhibitor of HCV replication and alters NS4B's subcellular distribution. Synonyms: Anguizole|442666-98-0|7- [chloro (difluoro ) methyl ] -5- (furan-2-yl ) -N- (thiophen-2-yl methyl ) pyrazolo [1, 5-a] pyrimidine-2-carboxamide |CS-0558|CHEMBL2170006|SCHEMBL14366829|D TXSID30359937|ZINC720413|BCP21132|An guizole, CAS: 442666-98-0|AKOS025149511|NCGC00379046-01|HY-13321|A924203|7- (Chloro difluoro methyl ) -5- (2-furanyl ) -N- (2-thienyl methyl ) pyrazolo [1, 5-a] pyrimidine-2-carboxamide |7- [chloro (difluoro ) methyl ] -5- (2-furyl ) -N- (2-thienyl methyl ) pyrazolo [1, 5-a] pyrimidine-2-carboxamide |7- [chloro (difluoro ) methyl ] -5-furan-2-yl -N- (thiophen-2-yl methyl ) pyrazolo [1, 5-a] pyrimidine-2 carboxamide. Grades: >98%. CAS No. 442666-98-0. Molecular formula: C17H11ClF2N4O2S. Mole weight: 408.81. | |
| Anhydroicaritin | β-Anhydroicaritin is an Icartin (I163680) derivative displaying anti-inflammatory activity and inhibition of human phosphodiesterase-5. Synonyms: 3,5,7-Trihydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-4H-chromen-4-one. Grades: >98%. CAS No. 38226-86-7. Molecular formula: C21H20O6. Mole weight: 368.4. | |
| Anhydronotoptol | Anhydronotoptol is found in the Notopterygii Rhizoma et Radix. Grades: > 95%. CAS No. 88206-51-3. Molecular formula: C21H20O4. Mole weight: 336.38. | |
| Anhydrovinblastin | immunosuppression. Uses: Immunosuppression. Synonyms: ANHYDROVINBLASTINE; Vinblastineanhydrous; Vincaleukoblastine, 3',4'-didehydro-4'-deoxy-; C11641; 3',4'-anhydrovinblastine; 3,4-ANHYDROVINBLASTINE,95%; ANHYDROVINBLASTIN; 3',4'-Didehydro-4'-deoxyvincaleukoblastine. Grades: >98%. CAS No. 38390-45-3. Molecular formula: C46H56N4O8. Mole weight: 792.96. | |
| Anidulafungin Impurity 1 | Anidulafungin Impurity 1 is an impurity of Anidulafungin, a new echinocandin antifungal agent with indications for use in esophageal candidiasis and candidemia. Molecular formula: C58H73N7O17. Mole weight: 1140.25. | |
| Anidulafungin Impurity 2 | Anidulafungin Impurity 2 is an impurity of Anidulafungin, a new echinocandin antifungal agent with indications for use in esophageal candidiasis and candidemia. Molecular formula: C5H12N2O4. Mole weight: 164.16. | |
| Anidulafungin Impurity 3 | Anidulafungin Impurity 3 is an impurity of Anidulafungin, a new echinocandin antifungal agent with indications for use in esophageal candidiasis and candidemia. Synonyms: 4-[4-(4-pentoxyphenyl)phenyl]benzoic acid; 4-[4-(4-pentoxyphenyl)phenyl]benzoic acid. Grades: ≥95%. CAS No. 158938-08-0. Molecular formula: C24H24O3. Mole weight: 360.45. | |
| Anidulafungin Impurity 4 | Anidulafungin Impurity 4 is an impurity of Anidulafungin, a new echinocandin antifungal agent with indications for use in esophageal candidiasis and candidemia. CAS No. 54615-51-9. Molecular formula: C6H11NO3. Mole weight: 145.16. | |
| Anidulafungin Impurity 5 | Anidulafungin Impurity 5 is an impurity of Anidulafungin, a new echinocandin antifungal agent with indications for use in esophageal candidiasis and candidemia. Molecular formula: C25H23NO7. Mole weight: 449.46. | |
| Anifrolumab | Anifrolumab is a monoclonal antibody that blocks the activity of type I interferon (IFN). Anifrolumab has been investigated for the treatment of systemic lupus erythematosus (SLE). Synonyms: Saphnelo. CAS No. 1326232-46-5. | |
| Aniline-2-sulfonic acid | Aniline-2-sulfonic acid (CAS# 88-21-1) is a useful research chemical. Synonyms: 2-aminobenzenesulfonic acid. Grades: 90 %. CAS No. 88-21-1. Molecular formula: C6H7NO3S. Mole weight: 173.19. | |
| Anilinium hypophosphite | Anilinium hypophosphite (CAS# 82395-88-8 ) is a useful research chemical. Synonyms: aniline;phosphenous acid. Grades: 95 %. CAS No. 82395-88-8. Molecular formula: C6H10NO2P. Mole weight: 159.12. | |
| Anilino(oxo)acetic acid | Anilino(oxo)acetic acid (CAS# 500-72-1) is a useful research chemical compound. Synonyms: 2-anilino-2-oxoacetic acid. CAS No. 500-72-1. Molecular formula: C8H7NO3. Mole weight: 165.15. | |
| Anisaldehyde dimethyl acetal | Anisaldehyde dimethyl acetal (CAS# 2186-92-7) is a reagent used in the synthesis of two possible diastereomers of natural 6-chlorotetrahydrofuran acetogenin. Synonyms: 1-(dimethoxymethyl)-4-methoxybenzene. Grades: 98.5 %. CAS No. 2186-92-7. Molecular formula: C10H14O3. Mole weight: 182.22. | |
| Anise Oil | Anise Oil is commonly used as a flavoring agent. Extractives and their physically modified derivatives. Pimpinella anisum, Umbelliferae. Synonyms: Essential oils, anise; Oils, essential, anise; Anise fruit oil; Anise seed oil; Aniseed oil; Oil of anise; Oils, anise; Oils, Pimpinella anisum; Oils, Pimpinellaanisum fruit; Pimpinella anisum fruit oil; Pimpinella anisum seed oil. CAS No. 8007-70-3. | |
| Anisodamine hydrobromide | Anisodamine is a naturally occurring atropine derivative, which is also known as 7β-hydroxyhyoscyamine. It is an anticholinergic and α1-adrenergic receptor as well as mAChR antagonist used in the treatment of acute circulatory shock in China. Synonyms: 6-Hydroxyhyoscyamine; phenoxymethanamine. Grades: ≥95%. CAS No. 55449-49-5. Molecular formula: C17H24BrNO4. Mole weight: 386.28. | |
| Annamycin | Annamycin liposomal is a liposome-encapsulated form of the semi-synthetic doxorubicin analogue annamycin with antineoplastic activity. Annamycin intercalates into DNA and inhibits topoisomerase II, resulting in the inhibition of DNA replication and repair and RNA and protein synthesis. Liposomal annamycin is less toxic and shows improved antitumor activity compared to annamycin. Uses: Antibiotics, antineoplastic. Synonyms: 2'-Iodo-3'-hydroxy-4'-epi-4-demethoxydoxorubicin; AR-522. CAS No. 92689-49-1. Molecular formula: C26H25IO11. Mole weight: 640.38. | |
| Anpirtoline hydrochloride | Anpirtoline hydrochloride is the hydrochloride salt of anpirtoline, which is a highly potent 5-HT1B receptor agonist with Ki values of 28 nM. It decreases central serotonin synthesis and attenuates aggressive behavior in vivo. It also acts as an antagonist at 5-HT3 receptors with Ki value of 29.5 nM and is brain penetrant. It is a receptor agonist with antinociceptive/antidepressant-like actions in rodents. Synonyms: Pyridine, 2-chloro-6-(4-piperidinylthio)-, hydrochloride (1:1); Pyridine, 2-chloro-6-(4-piperidinylthio)-, monohydrochloride; 2-Chloro-6-(piperidin-4-ylsulfanyl)pyridine hydrochloride; 2-Chloro-6-(piperidin-4-ylthio)pyridine hydrochloride; D16949; D-16949; D 16949. Grades: ≥99% by HPLC. CAS No. 99201-87-3. Molecular formula: C10H14Cl2N2S. Mole weight: 265.20. | |
| ANQ 11125 | ANQ 11125 has been found to be a motilin receptor antagonist. Synonyms: ANQ 11125; ANQ-11125; ANQ11125. Grades: ≥95% by HPLC. CAS No. 153966-48-4. Molecular formula: C86H125N19O21. Mole weight: 1761.05. | |
| ANR 94 | ANR 94 is an adenosine A2A antagonist. Synonyms: ANR 94; ANR94; ANR-94; 8-Ethoxy-9-ethyl-9H-purin-6-amine. CAS No. 634924-89-3. Molecular formula: C9H13N5O. Mole weight: 207.23. | |
| Ansofaxine hydrochloride | Ansofaxine hydrochloride is a triple reuptake inhibitor of serotonin (IC50 = 723 nM), dopamine (IC50 = 491 nM) and norepinephrine (IC50 = 763 nM). Synonyms: Ansofaxine HCl; LY-03005 hydrochloride; LY-03005 HCl; LY 03005 hydrochloride; LY 03005 HCl; LY03005 hydrochloride; LY03005 HCl. CAS No. 916918-84-8. Molecular formula: C24H32ClNO3. Mole weight: 417.97. | |
| Antalarmin hydrochloride | Antalarmin hydrochloride is the hydrochloride salt of antalarmin, which is a selective nonpeptide antagonist of the corticotropin-releasing hormone (CRH) receptor 1 with Ki value of 1 nM. It suppresses CRF-induced ACTH secretion and blocks CRF- and novelty-induced anxiety-like behavior in animal models of anxiety. It also can reduce cardiovascular, endocrinological and behavioral responses to stressful stimuli through its antagonism of central CRH signaling. It produces anti-inflammatory effects in arthritis models by reducing dose escalation in cocaine-addicted rats and suppresses stress-induced gastric ulceration related to irritable bowel syndrome. Synonyms: N-Butyl-N-ethyl-2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Monohydrochloride; N-Butyl-N-ethyl-2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Hydrochloride. Grades: ≥99% by HPLC. CAS No. 220953-69-5. Molecular formula: C24H35N4Cl. Mole weight: 415.01. | |
| Anthranil | Anthranil (CAS# 271-58-9) is a useful research chemical. Synonyms: 2,1-benzoxazole. CAS No. 271-58-9. Molecular formula: C7H5NO. Mole weight: 119.12. | |
| Anthranilyl-HIV Protease Substrate | Anthranilyl-HIV Protease Substrate is a hexapeptide FRET substrate derived from the p24/p15 cleavage site of the gag-pol polyprotein of the virus (excitation at 280 nm, emission at >435 nm). Synonyms: Abz-TI-Nle-F(4-NO2)-QR-NH2; (2-aminobenzoyl)-L-threonyl-L-isoleucyl-L-norleucyl-4-nitro-L-phenylalanyl-L-glutaminyl-L-argininamide; H-2Abz-Thr-Ile-Nle-Phe(4-NO2)-Gln-Arg-NH2; L-Argininamide, N-(2-aminobenzoyl)-L-threonyl-L-isoleucyl-L-norleucyl-4-nitro-L-phenylalanyl-L-glutaminyl-. Grades: 95%. CAS No. 133233-38-2. Molecular formula: C43H65N13O11. Mole weight: 940.06. | |
| Anthraquinone-2,7-disulfonic Acid Disodium Salt | Anthraquinone-2,7-disulfonic Acid Disodium Salt is a useful research chemical. Synonyms: Sodium anthraquinone-2,7-disulfonate; Disodium anthraquinone-2,7-disulfonate; 2,7-Anthracenedisulfonic acid, 9,10-dihydro-9,10-dioxo-, disodium salt. Grades: 80%. CAS No. 853-67-8. Molecular formula: C14H6Na2O8S2. Mole weight: 412.3. | |
| Anthraquinone-2-sulfonic acid sodium salt monohydrate | Anthraquinone-2-sulfonic acid sodium salt monohydrate was used to investigate the effects of reactant concentration and synthesis parameters on the electrical conductivity of polypyrrole coated polyethyleneterephthalate fabrics. It has been used as dopant in the preparation of polypyrrole films by electrochemical polymerization. Synonyms: sodium;9,10-dioxoanthracene-2-sulfonate;hydrate. Grades: 97 %. CAS No. 153277-35-1. Molecular formula: C14H7NaO5S ยท H2O. Mole weight: 328.27. | |
| Anthrone | Anthrone (CAS# 90-44-8) is a tricyclic aromatic ketone and related compound of anthracene. Anthrone is used as a reagent in the colorometric determination of carbohydrates. Dyes and metabolites. Synonyms: 10H-anthracen-9-one. Grades: 97 %. CAS No. 90-44-8. Molecular formula: C14H10O. Mole weight: 194.23. | |
| anti-3-Oxotricyclo[2.2.1.02,6]heptane-7-carboxylic acid | anti-3-Oxotricyclo[2.2.1.02,6]heptane-7-carboxylic acid (CAS# 50703-32-7 ) is a useful research chemical. Synonyms: (1S,2R,3R,4R,6S)-5-oxotricyclo[2.2.1.02,6]heptane-3-carboxylic acid. CAS No. 50703-32-7. Molecular formula: C8H8O3. Mole weight: 152.15. | |
| Antibiotic-202 | Antibiotic-202 has antibacterial property. Synonyms: Antibiotic-202; Antibiotic 202; Antibiotic202; 1-[2,7-bis[2-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]ethynyl]spiro[fluorene-9,4'-piperidine]-1'-yl]ethanone1-[2,7-Bis[2-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]ethynyl]spiro[fluorene-9,4'-piperidine]. CAS No. 1616113-45-1. Molecular formula: C35H39NO11. Mole weight: 649.68. | |
| Antide Acetate | Antide is a GnRH and LH-RH antagonist that displays potent anti-ovulatory and weak histamine release activity. Synonyms: N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-N6-(3-pyridinylcarbonyl)-L-lysyl-N6-(3-pyridinylcarbonyl)-D-lysyl-L-leucyl-N6-(1-methylethyl)-L-lysyl-L-prolyl-D-alaninamide, monoacetate. CAS No. 625092-10-6. Molecular formula: C84H112ClN17O16. Mole weight: 1651.30. | |
| anti-Diphenylglyoxime | anti-Diphenylglyoxime (CAS# 23873-81-6) is a useful research chemical. Synonyms: N-(2-hydroxyimino-1,2-diphenylethylidene)hydroxylamine. CAS No. 23873-81-6. Molecular formula: C14H12N2O2. Mole weight: 240.26. | |
| Antifreeze Polypeptide 6 (winter flounder) | Antifreeze polypeptides (AFP) have the common ability to lower the freezing point of serum, thus allowing fish to survive in sub-zero ocean temperatures. Type I AFPs are found in the blood of winter flounder, yellowtail flounder, Alaskan plaice, and the shorthorn and grubby sculpin. AFP37 (HPLC6) is isolated from the winter flounder, Pseudopleuronectes americanus, and consists of 37 amino acids arranged in three 11-residue repeats to form α-helices. Synonyms: AFP 6 (winter flounder); H-Asp-Thr-Ala-Ser-Asp-Ala-Ala-Ala-Ala-Ala-Ala-Leu-Thr-Ala-Ala-Asn-Ala-Lys-Ala-Ala-Ala-Glu-Leu-Thr-Ala-Ala-Asn-Ala-Ala-Ala-Ala-Ala-Ala-Ala-Thr-Ala-Arg-OH; L-alpha-aspartyl-L-threonyl-L-alanyl-L-seryl-L-alpha-aspartyl-L-alanyl-L-alanyl-L-alanyl-L-alanyl-L-alanyl-L-alanyl-L-leucyl-L-threonyl-L-alanyl-L-alanyl-L-asparagyl-L-alanyl-L-lysyl-L-alanyl-L-alanyl-L-alanyl-L-alpha-glutamyl-L-leucyl-L-threonyl-L-alanyl-L-alanyl-L-asparagyl-L-alanyl-L-alanyl-L-alanyl-L-alanyl-L-alanyl-L-alanyl-L-alanyl-L-threonyl-L-alanyl-L-arginine; HPLC-6 (winter flounder); AFP37 (winter flounder). Grades: ≥95%. CAS No. 122604-16-4. Molecular formula: C133H225N43O51. Mole weight: 3242.47. | |
| Antifungal agent 1 | A potent antifungalagent. Synonyms: 3-(4-chloroanilino)-6-hydroxy-9-methylcarbazole-1,4-dione. CAS No. 1265166-14-0. Molecular formula: C19H13ClN2O3. Mole weight: 352.77. | |
| Anti-Inflammatory Peptide 1 Acetate | Anti-Inflammatory Peptide 1 Acetate possesses a potent anti-inflammatory activity in vivo and is a strong inhibitor of phospholipase A2 (PLA2), whose increased presence and activity results in inflammation and pain at certain bodily sites. Molecular formula: C47H86N12O16S2. Mole weight: 1139.39. | |
| Antioxidant peptide A acetate | Antioxidant peptide A acetate acts as an antioxidant by reacting with reactive oxygen species such as superoxide radicals and hydroxyl radicals. Synonyms: H-PRO-HIS-CYS-LYS-ARG-MET-OH acetate; H-Pro-His-Cys-Lys-Arg-Met-OH.CH3CO2H; L-prolyl-L-histidyl-L-cysteinyl-L-lysyl-L-arginyl-L-methionine acetic acid. Grades: ≥95%. CAS No. 2918771-43-2. Molecular formula: C31H54N12O7S2.C2H4O2. Mole weight: 831.02. | |
| Antipain | Antipain, a protease inhibitor isolated from Actinomycetes, inhibits N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced transformation and increases chromosomal aberration. It restricts DNA synthesis and function of mice uterus. Uses: Protease inhibitors. Synonyms: [(S)-1-Carboxy-2-phenylethyl]carbamoyl-L-arginyl-L-valyl-argininal; L-valinamide, N2-[[((1S)-1-carboxy-2-phenylethyl)amino]carbonyl]-L-arginyl-N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-; Phe-CO-Arg-Val-L-Arg-H; N2-{[(1S)-1-Carboxy-2-phenylethyl]carbamoyl}-N5-(diaminomethylene)-L-ornithyl-N-{5-[(diaminomethylene)amino]-1-oxo-2-pentanyl}-L-valinamide. Grades: 95%. CAS No. 37691-11-5. Molecular formula: C27H44N10O6. Mole weight: 604.70. | |
| Antipain dihydrochloride | Antipain dihydrochloride, a protease inhibitor isolated from Actinomycetes, inhibits N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced transformation and increases chromosomal aberration. It restricts DNA synthesis and function of mice uterus. Synonyms: Antipain dihydrochloride from microbial source; N-(Nα-Carbonyl-Arg-Val-Arg-al)-Phe; N2-[((1S)-1-Carboxy-2-phenylethyl)carbamoyl]-N5-(diaminomethylene)-L-ornithyl-N-{5-[(diaminomethylene)amino]-1-oxo-2-pentanyl}-L-valinamide dihydrochloride; L-valinamide, N2-[[((1S)-1-carboxy-2-phenylethyl)amino]carbonyl]-L-arginyl-N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-, hydrochloride (1:2). Grades: ≥95%. CAS No. 37682-72-7. Molecular formula: C27H44N10O6.2HCl. Mole weight: 677.62. | |
| Antiparallel Dimer-AVP | Antiparallel Dimer-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: Anti-Parallel Dimer-Vasopressin; H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2.H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6', Cys1'-Cys6); 2[L-cystyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparginyl-L-cystyl-L-prolyl-L-arginyl-glycinamide] (inter-disulfide bridges between 1,6' and 1',6 cysteines). Molecular formula: C92H130N30O24S4. Mole weight: 2168.48. | |
| Antiparallel Dimer Oxytocin | Antiparallel Dimer Oxytocin is an impurity of Oxytocin, which is a mammalian neurohypophysial hormone used as a vasodilator agent. Synonyms: 2[L-cystyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparginyl-L-cystyl-L-leucyl-L-prolyl-L-glycinamide] (Inter-disulfide bridges between 1,6' and 1'6 cysteines); Oxytocin antiparallel dimer; β-Oxytocin dimer; Glycinamide, L-cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-leucyl-, bimol. cyclic (1?6'),(6?1')-bis(disulfide); L-cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-leucyl-glycinamide (1->6'),(6->1')-bis(disulfide) compound with L-cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-leucyl-glycinamide; H-Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2.H-Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (Disulfide bridge: Cys1-Cys6', Cys1'-Cys6). Grades: ≥95%. CAS No. 20054-93-7. Molecular formula: C86H132N24O24S4. Mole weight: 2014.39. | |
| anti-Pyruvic aldehyde 1-oxime | anti-Pyruvic aldehyde 1-oxime (CAS# 31915-82-9) is a useful research chemical. Synonyms: (1Z)-1-hydroxyiminopropan-2-one. Grades: 95 %. CAS No. 31915-82-9. Molecular formula: C3H5NO2. Mole weight: 87.08. | |
| Antirhine | Cas No. 16049-28-8. | |
| Antisauvagine-30 | Antisauvagine-30 is a selective, competitive and potent corticotropin-releasing factor CRF2 receptor antagonist with Kd values of 153.6 and 1.4 nM for binding to rat CRF1 and mouse CRF2β receptors respectively. It prevents stress-enhanced fear conditioning and MEK 1/2-dependent activation of ERK1/2 in mice in vivo. It inhibits sauvagine-stimulated cAMP accumulation in HEK-mCRF2β cells. Synonyms: (D-Phe11,His12)-Sauvagine (11-40); H-D-Phe-His-Leu-Leu-Arg-Lys-Met-Ile-Glu-Ile-Glu-Lys-Gln-Glu-Lys-Glu-Lys-Gln-Gln-Ala-Ala-Asn-Asn-Arg-Leu-Leu-Leu-Asp-Thr-Ile-OH; D-phenylalanyl-L-histidyl-L-leucyl-L-leucyl-L-arginyl-L-lysyl-L-methionyl-L-isoleucyl-L-alpha-glutamyl-L-isoleucyl-L-alpha-glutamyl-L-lysyl-L-glutaminyl-L-alpha-glutamyl-L-lysyl-L-alpha-glutamyl-L-lysyl-L-glutaminyl-L-glutaminyl-L-alanyl-L-alanyl-L-asparagyl-L-asparagyl-L-arginyl-L-leucyl-L-leucyl-L-leucyl-L-alpha-aspartyl-L-threonyl-L-isoleucine; 11-D-Phenylalanine-12-L-histidine-11-40-sauvagine (11-40). Grades: ≥95%. CAS No. 220673-95-0. Molecular formula: C161H274N48O46S. Mole weight: 3650.29. | |
| Antitrypanosomal agent 1 | Antitrypanosomal agent 1 is a potent and selective inhibitor of trypanothione reductase (TR), with an IC50 of 3.3 μM. It inhibits glutathione reductase (GR) (IC50 = 64.8 μM) and T. brucei (EC50 = 1 μM). Synonyms: 1-(3,4-Dichlorophenyl)-3-dimethylamino-1-propanone HCl; NSC-304108. Grades: ≥95%. CAS No. 75144-12-6. Molecular formula: C11H14Cl3NO. Mole weight: 282.59. | |
| Antitubercular agent-30 | Antitubercular agent-30 is an antibacterial agent against Mycobacterium tuberculosis (MIC=50 μg/mL). It has antitubercular activity. Synonyms: N-(4-nitrophenyl)-2-(2-thienyl)acetamide; N-(4-Nitro-phenyl)-2-thiophen-2-yl-acetamide; WAY-297407. CAS No. 384857-54-9. Molecular formula: C12H10N2O3S. Mole weight: 262.29. | |
| Antrafenine Dihydrochloride | Antrafenine Dihydrochloride is the dihydrochloride form of Antrafenine, which is a piperazine derivative drug. It acts as an analgesic and anti-inflammatory drug, but is not widely used. Uses: Antrafenine dihydrochloride acts as an analgesic and anti-inflammatory drug. Synonyms: 2-[[7-(TrifluoroMethyl)-4-quinolinyl]amino]benzoic Acid [4-[3-(TrifluoroMethyl)phenyl]-1-piperazinyl]ethyl Ester dihydrochloride; Benzoic acid, 2-((7-(trifluoromethyl)-4-quinolinyl)amino)-, 2-(4-(3-(trifluoromethyl)phenyl)-1-piperazinyl)ethyl ester, dihydrochloride. Grades: 98%. CAS No. 55300-30-6. Molecular formula: C30H28Cl2F6N4O2. Mole weight: 661.47. | |
| ANX-510 | ANX-510 is a folate-based biomodulator with potential antineoplastic activity. 5,10-methylenetetrahydrofolate (MTHF) stabilizes the covalent binding of the fluorouracil metabolite 5-5-fluoro-2'-deoxyuridine-5'-O-monophosphate (FdUMP) to its target enzyme, thymidylate synthase, which results in inhibition of thymidylate synthase, depletion of thymidine triphosphate (TTP), a necessary constituent of DNA, and tumor cell death. Synonyms: 5,10-Methylenetetrahydrofolic acid; 5,10-Methylene-tetrahydrofolate; Tetrahydromethylenefolate; N-{4-[3-amino-1-oxo-1,2,5,6,6a,7-hexahydroimidazo[1,5-f]pteridin-8(9H)-yl]benzoyl}-L-glutamic acid. CAS No. 3432-99-3. Molecular formula: C20H23N7O6. Mole weight: 457.44. | |
| AOD9604 acetate | AOD9604 acetate is a modified fragment of human growth hormone (hGH) that was originally developed as an anti-obesity drug. AOD9604 is formulated as the injection for weight loss, muscle building and so on. Synonyms: AOD-9604 acetate; AOD 9604 acetate; H-Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe-OH.CH3CO2H (Disulfide bridge: Cys7-Cys14); L-tyrosyl-L-leucyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-cysteinyl-L-arginyl-L-seryl-L-valyl-L-alpha-glutamyl-glycyl-L-seryl-L-cysteinyl-glycyl-L-phenylalanine (7->14)-disulfide acetic acid; LAT 8881 acetate. Grades: ≥95%. Molecular formula: C80H127N23O25S2. Mole weight: 1875.15. | |
| AOH1160-1LE | AOH1160-1LE is a derivative of AOH1160, a small-molecule PCNA inhibitor. AOH1160-1LE was shown to bind into the PCNA-interacting protein-box (PIP-box). Molecular formula: C28H24N2O5. Mole weight: 468.50. | |
| AOH1996 | AOH1996 is a small-molecule PCNA inhibitor that enhances the interaction between PCNA and the largest subunit of RNA polymerase II, RPB1, and dissociates PCNA from actively transcribed chromatin regions, while inducing DNA double-stranded breaks in a transcription-dependent manner. AOH1996 was identified as a selective chemotherapeutic. Synonyms: AOH 1996; AOH-1996; NSC789796; NSC-789796. CAS No. 2089314-64-5. Molecular formula: C26H22N2O4. Mole weight: 426.46. | |
| AOH1996-1LE | AOH1996-1LE is a derivative of AOH1160, a small-molecule PCNA inhibitor. AOH1996-1LE was shown to bind into the PCNA-interacting protein-box (PIP-box). | |
| AP 1189 | AP 1189 exhibits biased agonistic activity towards the melanocortin 1 and melanocortin 3 receptors. Synonyms: Hydrazinecarboximidamide, 2-[(2E)-3-[1-(2-nitrophenyl)-1H-pyrrol-2-yl]-2-propen-1-ylidene]-, acetate (1:1), (2E)-; AP1189; AP-1189; Resomelagon acetate; (E)-2-((E)-3-(1-(2-nitrophenyl)-1H-pyrrol-2-yl)allylidene)hydrazine-1-carboximidamide acetate. Grades: ≥95%. CAS No. 1809420-72-1. Molecular formula: C14H14N6O2.C2H4O2. Mole weight: 358.35. | |
| AP18 | AP18 is a selective Transient receptor potential A1(TRPA1) channel blocker which reversibly inhibits TRPA1 with IC50 values of 3.1 and 4.5 μM at human and mouse respectively. It has been used to study TRPA1 signaling in mice and rats as well as in vitro. It blocks the transient receptor potential ankyrin 1 receptors and can reduce chronic pain associated with arthritis. It also blocks cinnamaldehyde-induced nociception in vivo and blocks cold- and mustard oil-induced activation of mouse TRPA1 but not capsaicin-induced activation. It reverses CFA-induced mechanical hyperalgesia in mice. Uses: Ap18 blocks the transient receptor potential ankyrin 1 receptors and can reduce chronic pain associated with arthritis. Synonyms: AP-18; AP 18; AP18. 4-(4-Chlorophenyl)-3-methylbut-3-en-2-oxime;AP-18;4-(4-Chlorophenyl)-3-methyl-3-buten-2-oneoxime;(NE)-N-[(Z)-4-(4-chlorophenyl)-3-methylbut-3-en-2-ylidene]hydroxylamine;(2E,3E)-4-(4-chlorophenyl)-3-methylbut-3-en-2-one oxime. Grades: 98%. CAS No. 55224-94-7. Molecular formula: C11H12ClNO. Mole weight: 209.67. | |
| AP1867 | AP1867 is a precursor for the dTAG system which pairs a novel degrader of FKBP12(F36V) with expression of FKBP12(F36V) in-frame with a protein of interest. Synonyms: AP 1867; 3- (3- ( (R) -3- (3, 4-Dimethoxyphenyl) -1- ( ( (S) -1- ( (S) -2- (3, 4, 5-trimethoxyphenyl) butanoyl) -piperidine-2-carbonyl) oxy) propyl) phenoxy) propanoic acid. CAS No. 195514-23-9. Molecular formula: C38H47NO11. Mole weight: 693.78. | |
| AP1867-2-(carboxymethoxy) | AP1867-2-(carboxymethoxy), the AP1867 (a synthetic FKBP12F36V-directed ligand) based moiety, binds to CRBN ligand via a linker to form dTAG molecules. It is a ligand and a binder that contributes to the enhancer-promoter structural interactions of DNA elements. Synonyms: PROTAC FKBP12-binding moiety 2; 2-(2-((R)-3-(3,4-Dimethoxyphenyl)-1-(((S)-1-((S)-2-(3,4,5-trimethoxyphenyl)butanoyl)piperidine-2-carbonyl)oxy)propyl)phenoxy)acetic acid; 2-Piperidinecarboxylic acid, 1-[(2S)-1-oxo-2-(3,4,5-trimethoxyphenyl)butyl]-, (1R)-1-[2-(carboxymethoxy)phenyl]-3-(3,4-dimethoxyphenyl)propyl ester, (2S)-; Ortho-AP1867. Grades: ≥96%. CAS No. 2230613-03-1. Molecular formula: C38H47NO11. Mole weight: 693.78. | |
| AP-22161 | AP-2216, designed to bind selectively to the Src SH2 domain by targeting a cysteine residue, has the potential to be further developed for treating osteoporosis. Synonyms: 4-[(2S)-2-acetamido-3-[[(5S)-3-carbamoyl-2-(cyclohexylmethoxy)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-yl]amino]-3-oxopropyl]-2-formylbenzoic acid; AP-22161; AP 22161; AP22161; SCHEMBL7243003; G7VE62573J; UNII-G7VE62573J. Grades: >98%. CAS No. 268741-42-0. Molecular formula: C32H39N3O7. Mole weight: 577.67. | |
| AP2238 | AP2238 is a inhibitor of both acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation. Uses: Cholinesterase inhibitors. Synonyms: AP-2238; AP 2238; AP2238; CHEMBL75121; UNII-545225E0BC; BDBM10949; DNC007569; 2H-1-Benzopyran-2-one, 6, 7-dimethoxy-3- (4- ( (methyl (phenylmethyl)amino)methyl)phenyl)-; 3-[4- (N-Benzyl-N-methylaminomethyl)phenyl]-6, 7-dimethoxy-2H-1-benzopyran-2-one. Grades: 98%. CAS No. 553681-56-4. Molecular formula: C26H25NO4. Mole weight: 415.48. | |
| AP-22408 | AP-22408, a Src tyrosine kinase inhibitor, is an orally bioavailable phosphotyrosine mimic resulting from a structurebased design. Synonyms: [4-[(2S)-2-acetamido-3-[[(5S)-3-carbamoyl-2-(cyclohexylmethoxy)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-yl]amino]-3-oxopropyl]-2-phosphonophenyl]phosphonic acid; AP-22408; AP 22408; AP22408; UNII-3U3L5QR4KV; CC1; AC1L9I7C; 3U3L5QR4KV; SCHEMBL7245569. Grades: >98%. CAS No. 268741-43-1. Molecular formula: C30H41N3O10P2. Mole weight: 665.61. | |
| AP23464 | AP23464 is a potent adenosine 5'-triphosphate (ATP)-based inhibitor of Src and Abl kinases. It displays antiproliferative activity against a human CML cell line and Bcr-Abl-transduced Ba/F3 cells with an IC50=14 nM. Synonyms: AP-23464; AP 23464; (4-((2-cyclopentyl-9-(3-hydroxyphenethyl)-9H-purin-6-yl)amino)phenyl)dimethylphosphine oxide. Grades: >98%. CAS No. 845895-51-4. Molecular formula: C30H38N5O2P. Mole weight: 475.53. | |
| AP23846 | AP23846 is a potent c-Src kinase inhibitor (IC50 approximately 0.5 nmol/L in vitro, approximately 10-fold more potent than PP2, the most widely used commercially available Src family kinase inhibitor). Synonyms: AP-23846; (4-((2-cyclopentyl-9-ethyl-9H-purin-6-yl)amino)phenyl)dipropylphosphine oxide. Grades: >98%. CAS No. 878654-51-4. Molecular formula: C20H16FN3O2. Mole weight: 439.53. | |
| AP23848 | AP23848 is a potent Bcr-Abl inhibitor. Synonyms: AP-23848; AP 23848; PF-562771; (4-((2-Cyclopentyl-9-(3-hydroxyphenethyl)-9H-purin-6-yl)amino)phenyl)dipropylphosphine oxide. Grades: >98%. CAS No. 834894-21-2. Molecular formula: C13H15N5O6. Mole weight: 531.63. | |
| AP6A Sodium salt | AP6A Sodium salt is the salt of AP6A, a potent vasoconstrictor. Synonyms: P1-(5'-Adenosyl) P6-(5'-adenosyl) hexaphosphate Sodium salt; Diadenosine hexaphosphate Sodium salt; P1,P6-di(Adenosine-5')hexaphosphate Sodium salt; Diadenosine 5',5''''-P1,P6-hexaphosphate Sodium salt; AppppppA Sodium salt; Ap(6)A Sodium salt; Adenosine-(5')-hexaphospho-(5')-adenosine Sodium salt; Adenosine 5'-hexaphosphate 5'-ester with adenosine Sodium salt; P1,P6-Bis(5'-adenosyl)hexaphosphate Sodium salt. Grades: ≥95% by HPLC. Molecular formula: C20H30N10O25P6 (free acid). Mole weight: 996.35 (free acid). | |
| APC-100 | APC-100 is an orally available, vitamin E derivative and androgen receptor (AR) antagonist with potential anti-oxidant, chemopreventative and antineoplastic activity. APC-100 binds to ARs in target tissues thereby inhibiting androgen-induced receptor activation and facilitating the formation of inactive complexes that cannot be translocated to the nucleus. APC-100 may ultimately lead to an inhibition of growth in both AR-dependent and AR-independent prostate tumor cells. Uses: Antioxidants. Synonyms: 2,2,5,7,8-Pentamethyl-6-chromanol; Chromanol; 6-Hydroxy-2,2,5,7,8-pentamethylchroman; APC100; 3,4-Dihydro-2,2,5,7,8-pentamethyl-2H-1-Benzopyran-6-ol. Grades: 98%. CAS No. 950-99-2. Molecular formula: C14H20O2. Mole weight: 220.312. | |
| APC-6336 | APC-6336 is a Hepatitis C virus NS3 protein inhibitor. Synonyms: (2R)-2-[[2-[(6-carbamoyl-1H-benzimidazol-2-yl)methyl]-3-methylbenzimidazole-5-carbonyl]amino]-3-phosphonopropanoic acid; APC-6336; APC 6336; APC6336; UNII-4124YUO44Z; CRA-6336; 4124YUO44Z. Grades: >98%. CAS No. 263870-19-5. Molecular formula: C21H21N6O7P. Mole weight: 500.4. | |
| Apcin | Apcin is an inhibitor of the E3 ligase activity of the mitotic anaphase-promoting complex/cyclosome (APC/C), which is a large multimeric complex. It functions as a ubiquitin ligase, initiating the metaphase-anaphase transition and regulating ordered transitions through the cell cycle by controlling the ubiquitin-mediated proteolysis of cell cycle proteins. It competitively binds to the D-box binding site of Cdc20 and prevents substrate recognition and ubiquitylation required for continuation of mitosis. It synergistically increases apoptosis in multiple myeloma cells in combination with proTAME (prodrug of TAME). It also prolongs mitotic duration in RPE1 cells in combination with proTAME in vitro. It blocks mitotic exit and being synergistically amplified by co-addition of Ts-Arg-OMe. Synonyms: 3-(2-Methyl-5-nitro-imidazol-1-yl)-N-(2,2,2-trichloro-1-phenylamino-ethyl)-propionamide; 2-(2-Methyl-5-nitroimidazol-1-yl)ethyl N-[2,2,2-trichloro-1-(pyrimidin-2-ylamino)ethyl]carbamate; [2,2,2-trichloro-1-(2-pyrimidinylamino)ethyl]-carbamic acid, 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl ester. Grades: ≥98% by HPLC. CAS No. 300815-04-7. Molecular formula: C13H14Cl3N7O4. Mole weight: 438.65. | |
| Apcin-A | Apcin-A is an anaphase-promoting complex (APC) inhibitor. Apcin-A interacts strongly with Cdc20, and inhibits the ubiquitination of Cdc20 substrates. Synonyms: Apcin-A; 1683617-62-0; 3-Aminopropyl (2,2,2-trichloro-1-(pyrimidin-2-ylamino)ethyl)carbamate; starbld0000888; SCHEMBL22567019; EX-A5236; AKOS030257613; MS-25252; HY-130841; CS-0114386. CAS No. 1683617-62-0. Molecular formula: C10H14Cl3N5O2. Mole weight: 342.61. | |
| APcK110 | KIT inhibitor; inhibits phosphorylation of KIT, STAT3, STAT5 and Akt. Suppresses proliferation of OCI/AML3 cells (IC50 = 175 nM). Caspase-dependant apoptosis inducer. Synonyms: APcK 110; APcK-110; 6-(3,5-Dimethoxyphenyl)-3-(4-fluorophenyl)-1H-pyrazolo[3,4-b]pyridine. Grades: >98%. CAS No. 1001083-74-4. Molecular formula: C34H49N5O6. Mole weight: 349.36. | |
| APD597 (JNJ-38431055) | APD597, also known as JNJ-38431055, is a potent and selective GPR119 agonist, which is potential useful for the treatment of type 2 diabetes. GPR119 agonists mediate a unique nutrient-dependent dual elevation of both insulin and glucagon like peptide 1/glucose-dependent insulinotropic peptide levels in vivo. Synonyms: APD597; APD-597; APD 597; JNJ-38431055; JNJ 38431055; JNJ38431055. Grades: 98%. CAS No. 897732-93-3. Molecular formula: C21H29N5O6S. Mole weight: 479.55. | |
| APD668 | APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119 respectively. Synonyms: APD668; APD-668; APD 668; JNJ28630368; JNJ-28630368; JNJ 28630368. Grades: 0.99. CAS No. 832714-46-2. Molecular formula: C21H24FN5O5S. Mole weight: 477.511. | |
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