BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| AMG-47a | AMG-47a is a potent inhibitor of Lck and T cell proliferation. It has anti-inflammatory activity (ED50 = 11 mg/kg) in the anti-CD3 induced production of IL-2 in mice. It displays subnanomolar inhibition against Lck, and low inhibition against other hard to inhibit kinases in several other in vitro assays. It effectively inhibits the JNK family of kinases including TYK2 at ~ 1.2 μM but well under 10 μM. It selectively reduced the levels of EGFP-KRASG12V protein but did not affect EGFP protein in cells. Uses: Amg-47a has anti-inflammatory activity. Synonyms: AMG-47a; AMG 47a; AMG47a; AMG-47; AMG 47; AMG47. 4-Methyl-3-[2-[[2-(4-morpholinyl)ethyl]amino]-6-quinazolinyl]-N-[3-(trifluoromethyl)phenyl]benzamide. Grades: 95%. CAS No. 882663-88-9. Molecular formula: C29H28F3N5O2. Mole weight: 535.56. |  |
| AMG 487 | AMG 487 is a CXCR3 antagonist that inhibits cell migration and metastasis. Synonyms: AMG-487; AMG 487; AMG487. Benzeneacetamide, N-((1R)-1-(3-(4-ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl)ethyl)-N-(3-pyridinylmethyl)-4-(trifluoromethoxy)-; N-[(1R)-1-[3-(4-ethoxyphenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(pyridin-3-ylmethyl)-2-[4-(trifluorome. CAS No. 473719-41-4. Molecular formula: C32H28F3N5O4. Mole weight: 603.59. | |
| AMG-517 | AMG-517 is a potent and selective TRPV1 antagonist, antagonizes capsaicin, proton, and heat activation of TRPV1 with IC50 of 0.76 nM, 0.62 nM and 1.3 nM. Synonyms: AMG-517; AMG 517; AMG517; BD-0082; BD 0082; BD0082; BAY E 9736. Grades: >98%. CAS No. 659730-32-2. Molecular formula: C20H13F3N4O2S. Mole weight: 430.4. | |
| AMG 548 | AMG-548 is a selective p38α inhibitor with Ki value of 0.5nM. It displays >1000-fold selectivity against 36 other kinases, and it can inhibit whole blood LPS-stimulated TNF&alpha. In Sep 2008, Preclinical for Rheumatoid arthritis in USA was discontinued. Uses: Inflammation; rheumatoid arthritis. Synonyms: AMG 548; AMG-548; AMG548; UNII-PGR0H531I4; 2-[[(2S)-2-Amino-3-phenylpropyl]amino]-3-methyl-5-(2-naphthalenyl)-6-(4-pyridinyl)-4(3H)-pyrimidinone. Grades: 98%. CAS No. 864249-60-5. Molecular formula: C29H27N5O. Mole weight: 461.56. | |
| AMG-628 | AMG-628 is a highly selective, ATP-competitive inhibitor of Raf kinases. It can inhibit activation of tyrosine protein kinases. AMG-628 can also inhibit growth, and induce cell cycle arrest and apoptosis in colon and melanoma cell lines with the B-RafV600E mutation. Synonyms: AMG-628; AMG 628; AMG628; UNII-28J966TN3X; CHEMBL226574;N-(4-((6-(4-(1-(4-fluorophenyl)ethyl)-1-piperazinyl)-4-pyrimidinyl)oxy)-2-benzothiazolyl)-Acetamide. Grades: 98%. CAS No. 862269-73-6. Molecular formula: C25H25FN6O2S. Mole weight: 492.57. | |
| AMG 837 | AMG 837 sodium salt is a potent GPR40 agonist with a superior pharmacokinetic profile and robust glucose-dependent stimulation of insulin secretion in rodents. It displayed the expected two-fold increase in potency on GPR4 compared to the racemic compound and its activity crossed over to the rat and mouse forms of GPR40. It is a highly potent stimulator of insulin secretion in MIN6 cells with an EC50 comparable to that seen in the aequorin Ca2+-flux assay. It was a potent partial agonist in the calcium flux assay on the GPR40 receptor and potentiated glucose stimulated insulin secretion in vitro and in vivo. Synonyms: AMG-837, AMG837, AMG 837. Grades: >98%. CAS No. 865231-46-5. Molecular formula: C26H21F3O3. Mole weight: 438.44. | |
| AMG 837 calcium hydrate | AMG 837 calcium hydrate is a potent GPR40 agonist(EC50=13 nM) with a superior pharmacokinetic profile and robust glucose-dependent stimulation of insulin secretion in rodents. Synonyms: AMG-837; AMG837; AMG 837. Grades: 0.98. CAS No. 1259389-38-2. Molecular formula: C52H42CaF6O7. Mole weight: 455.45. | |
| AMG 837 hemicalcium salt | The calcuim salt form of AMG 837, which has been found to be a GPR40 partial agonist and could probably be used as an antidiabetic agent. Synonyms: AMG 837 hemicalcium salt; AMG837 hemicalcium salt; AMG-837 hemicalcium salt; (βS)-β-1-Propyn-1-yl-4-[[4'-(trifluoromethyl)[1,1'-biphenyl]-3-yl]methoxy]benzenepropanoic acid hemicalcium salt. Grades: ≥98% by HPLC. CAS No. 1291087-14-3. Molecular formula: C26H20F3O3.½Ca. Mole weight: 457.47. | |
| AMG 837 sodium salt | AMG 837 sodium salt is a potent GPR40 agonist with a superior pharmacokinetic profile and robust glucose-dependent stimulation of insulin secretion in rodents. It displayed the expected two-fold increase in potency on GPR4 compared to the racemic compound and its activity crossed over to the rat and mouse forms of GPR40. It is a highly potent stimulator of insulin secretion in MIN6 cells with an EC50 comparable to that seen in the aequorin Ca2+-flux assay. It was a potent partial agonist in the calcium flux assay on the GPR40 receptor and potentiated glucose stimulated insulin secretion in vitro and in vivo. Synonyms: AMG-837 sodium; AMG837 sodium; AMG 837 sodium; AMG-837 sodium salt. Grades: >98%. CAS No. 865231-45-4. Molecular formula: C26H20F3NaO3. Mole weight: 460.42. | |
| AMG8562 | AMG8562 is a novel vanilloid receptor TRPV1 modulator. Synonyms: AMG-8562; AMG8562; AMG 8562; (E)-N-[(2R)-2-hydroxy-2,3-dihydro-1H-inden-4-yl]-3-[2-piperidin-1-yl-4-(trifluoromethyl)phenyl]prop-2-enamide;AMG-8562;2-Propenamide, N-((2R)-2,3-dihydro-2-hydroxy-1H-inden-4-yl)-3-(2-(1-piperidinyl)-4-(trifluoromethyl)phenyl)-, (2E)-. Grades: >98 %. CAS No. 1041478-78-7. Molecular formula: C24H25F3N2O2. Mole weight: 430.47. | |
| AMG-8718 | This active molecular is a potent BACE1 inhibitor that is a potential target for the treatment of Alzheimer's disease. AMG-8718 produced significantly reductions of CSF and brain Aβ levels in animal models. It also exhibited reduced potential for QTc elongation in a cardiovascular safety model. BACE1 inhibition has direct efficacy in the Alzheimer's disease pathology but it does not affect viability largely. Uses: The treatment of alzheimer's disease. Synonyms: AMG8718; AMG 8718; AMG-8718. (4S)-7'-(2-fluoropyridin-3-yl)-3'-[2-(3-methyloxetan-3-yl)ethynyl]spiro[5H-1,3-oxazole-4,5'-chromeno[2,3-b]pyridine]-2-amine. Grades: 98%. CAS No. 1215868-94-2. Molecular formula: C25H19FN4O3. Mole weight: 442.45. | |
| AMG-978 | AMG-978 is an inhibitor of beta-secretase 1 (BACE1) (IC50 = 27 nM) which is in the preclinical study for the treatment of Alzheimer's disease. Uses: The potential treatment of alzheimer's disease. Synonyms: AMG 978; AMG978. | |
| AMG-9810 | AMG-9810 is potent, non-vanilloid and selective TRPV1 receptor antagonist with IC50 value of 17 nM. It inhibits capsaicin-, proton-, heat- and endogenous ligand-induced activation of human and rat recombinant TRPV1 receptors. It displays antihyperalgesic properties in a rat model of inflammatory pain. It was developed by Amgen. Uses: Amg-9810 displays antihyperalgesic properties. Synonyms: AMG-9810; AMG9810; AMG 9810. (2E)-N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-[4-(1,1-dimethylethyl)phenyl]-2-propanamide;2-PropenaMide, N-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[4-(1,1-diMethylethyl)phenyl]-, (2E)-;(E)-3-(4-tert-butylphenyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)prop-2-enami. Grades: 98%. CAS No. 545395-94-6. Molecular formula: C21H23NO3. Mole weight: 337.41. | |
| AMG PERK 44 | AMG PERK 44 is a potent and selective PERK inhibitor with IC50 of 6 nM, which exhibits 160-fold selectivity over B-Raf, GCN2 and a panel of 387 other kinases. Synonyms: 4-[2-Amino-4-methyl-3-(2-methyl-6-quinolinyl)benzoyl]-1,2-dihydro-1-methyl-2,5-diphenyl-3H-pyrazol-3-one hydrochloride. Grades: ≥98%. CAS No. 1883548-84-2. Molecular formula: C34H28N4O2·HCl. Mole weight: 561.07. | |
| AMI-193 | AMI-193 has been found to be a selective 5-HT antagonist and could be also used as a starting reagent in some pharmaceutical synthesis. Synonyms: Spiramide; R 5808; R-5808; R5808; 8-[3-(4-Fluorophenoxy)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]-decanone. Grades: ≥99% by HPLC. CAS No. 510-74-7. Molecular formula: C22H26FN3O2. Mole weight: 383.46. | |
| Amidantel | Amidantel is a bio-active chemical compound. It is used as anthelmintics. Uses: Amidantel is used as anthelmintics. Synonyms: Amidantel free base; Amidantelum; 4'-((1-(Dimethylamino)ethylidene)amino)-2-methoxyacetanilide; Bay-d-8815. Grades: 98%. CAS No. 49745-00-8. Molecular formula: C13H19N3O2. Mole weight: 249.31. | |
| Amikacin hydrate | Amikacin hydrate is an aminoglycoside antibiotic and a semisynthetic analog of kanamycin. Amikacin works by binding to the bacterial 30S ribosomal subunit, causing misreading of mRNA and leaving the bacterium unable to synthesize proteins vital to its growth. Synonyms: BAY 41-6551 hydrate. Grades: >98%. CAS No. 1257517-67-1. Molecular formula: C22H45N5O14. Mole weight: 603.62. | |
| Amiloride HCl | Amiloride HCl is a relatively selective inhibitor of the epithelial sodium channel, used in the management of hypertension and congestive heart failure. Uses: Acid sensing ion channel blockers. Synonyms: Amiloride HCl anhydrous; Amiloride (hydrochloride); Amiloride hydrochloride anhydrous; MK-870 hydrochloride; N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride. Grades: ≥ 98%. (HPLC). CAS No. 2016-88-8. Molecular formula: C6H9Cl2N7O. Mole weight: 266.09. | |
| Amino(3,5-dimethyl-1H-pyrazol-4-yl)acetic acid | Amino(3,5-dimethyl-1H-pyrazol-4-yl)acetic acid (CAS# 67809-62-5) is a useful research chemical. Synonyms: 2-amino-2-(3,5-dimethyl-1H-pyrazol-4-yl)acetic acid. Grades: 95 %. CAS No. 67809-62-5. Molecular formula: C7H11N3O2. Mole weight: 169.18. | |
| Aminoacetaldehyde diethyl acetal | Aminoacetaldehyde diethyl acetal (CAS# 645-36-3) is a useful synthetic intermediate. It can be used as a building block for imidazole containing compounds such as 5-bromo-2-(1H-imidazol-2-yl)pyridine and heteroaryl-2-imidazoles. Synonyms: 2,2-diethoxyethanamine. Grades: 95 %. CAS No. 645-36-3. Molecular formula: C6H15NO2. Mole weight: 133.19. | |
| Aminoacetonitrile | Aminoacetonitrile (CAS# 540-61-4) is used in preparation of the Heterocyclic compounds and their medical applications. Synonyms: 2-aminoacetonitrile. CAS No. 540-61-4. Molecular formula: C2H4N2. Mole weight: 56.07. | |
| Aminoallyl-UTP-ATTO-680 | Aminoallyl-UTP-ATTO-680 is recommended for direct enzymatic labeling of DNA/cDNA, such as PCR and Nick Translation. It was incorporated as an alternative to its natural counterpart, dTTP. The resulting dye-labeled DNA/cDNA probes are ideal for fluorescent hybridization applications such as FISH or microarray-based gene expression profiling. Synonyms: 5-(3-Aminoallyl)-uridine-5'-triphosphate, labeled with ATTO 680, Triethylammonium salt. Grades: ≥95% by HPLC. Molecular formula: C39H49N6O20P3S (free acid). Mole weight: 1046.82 (free acid). | |
| Aminobutyl-DOTA-tris(t-butyl ester) | Aminobutyl-DOTA-tris(t-butyl ester) is a bifunctional chelating agent. Synonyms: Tri-tert-butyl 2,2',2''-(10-(2-((4-aminobutyl)amino)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate; 1,4,7,10-Tetraazacyclododecane-1,4,7-tris(t-butyl acetate)-10-(4-aminobutyl)acetamide. CAS No. 1402393-59-2. Molecular formula: C32H62N6O7. Mole weight: 642.87. | |
| Aminocardiolipin | Amino-CL can be modified with or attached to amine reactive probes/surfaces. Cardiolipin (CL) is an important component in prokaryotic and in eukaryotic inner mitochondrial membranes. Monolysocardiolipin is an intermediate in CL remodeling, and acetyl transferase tafazzin mutations impairing linoleic acid transfer to MCL are considered the main reason of Barth syndrome. Synonyms: Amino-CL. Molecular formula: C69H135NO17P2. Mole weight: 1312.78. | |
| Aminodiphenylmethane hydrochloride | Aminodiphenylmethane hydrochloride (CAS# 5267-34-5) is used as molecular tools to block maturation of nuclear lamin A and decelerate cancer cell migration. Synonyms: diphenylmethanamine;hydrochloride. CAS No. 5267-34-5. Molecular formula: C13H14ClN. Mole weight: 219.71. | |
| Aminoethyl desmethoxy fluvoxamine | An impurity of Fluvoxamine Maleate, a selective serotonin reuptake inhibitor (SSRI) used to treat obsessive compulsive disorder (OCD). Synonyms: (E)-1-[4-(Trifluoromethyl)phenyl]pentan-1-one O-{2-[(2-aminoethyl)amino]ethyl}oxime. Molecular formula: C16H24F3N3O. Mole weight: 331.38. | |
| Aminoferrocene | Aminoferrocene (CAS# 1273-82-1 ) is a useful research chemical. Synonyms: FERROCENYLAMINE; AMINOFERROCENE. Grades: > 96.0 % (GC) (T). CAS No. 1273-82-1. Molecular formula: C10H11FeN. Mole weight: 201.05. | |
| Aminoguanidine hydrochloride | Aminoguanidine hydrochloride is the hydrochloride salt form of Aminoguanidine. Aminoguanidine is an inhibitor that has an irreversible function on iNOS with selectivity against eNOS and nNOS. IC50: iNOS= 5.4 μM; rat nNOS= 160 μM. Synonyms: 2-aminoguanidine;hydrochloride. CAS No. 1937-19-5. Molecular formula: CH7ClN4. Mole weight: 110.55. | |
| Aminomalononitrile p-toluenesulfonate | Aminomalononitrile p-toluenesulfonate (CAS# 5098-14-6) is a reagent for diazonamide synthesis via heck endocyclization. It may also have implications for developing IκB Kinase-β inhibitors. Synonyms: 2-aminopropanedinitrile;4-methylbenzenesulfonic acid. Grades: 95 %. CAS No. 5098-14-6. Molecular formula: C10H11N3O3S. Mole weight: 253.28. | |
| Aminooxyacetic Acid | Aminooxyacetic acid, often abbreviated AOA or AOAA, is a GABA transaminase (GABA-T) inhibitor (Ki = 9.16 μM) that inhibits 4-aminobutyrate aminotransferase (GABA-T) activity in vitro and in vivo, leading to less gamma-aminobutyric acid (GABA) being broken down. Subsequently, the level of GABA is increased in tissues. At concentrations high enough to fully inhibit 4-aminobutyrate aminotransferase activity, aminooxyacetic acid is indicated as a useful tool to study regional GABA turnover in rats. AOAA is also an inhibitor of pyridoxal phosphate (PLP)-dependent enzymes, which serve as an inhibitor by attacking the Schiff base linkage between PLP and the enzyme, forming oxime type complexes. Uses: Gaba agents. Synonyms: Aminooxyacetate; AOAA; 2-Aminooxyacetic acid; U 7524; U7524; U-7524. Grades: ≥95%. CAS No. 645-88-5. Molecular formula: C2H5NO3. Mole weight: 91.07. | |
| Amino-PEG10-t-butyl Ester | Amino-PEG10-t-butyl Ester (CAS# 1818294-42-6 ) is a useful research chemical. Synonyms: Amino-PEG10-COOtBu; 3- [2- [2- [2- [2- [2- [2- [2- [2- [2- (2-aminoethoxy) ethoxy] ethoxy] ethoxy] ethoxy] ethoxy] ethoxy] ethoxy] ethoxy] ethoxy] propanoic acid tert-butyl ester; 2-Methyl-2-propanyl 1-amino-3,6,9,12,15,18,21,24,27,30-decaoxatritriacontan-33-oate; 3,6,9,12,15,18,21,24,27,30-Decaoxatritriacontan-33-oic acid, 1-amino-, 1,1-dimethylethyl ester; H2N-PEG10-CH2CH2COOtBu; Amino-PEG10-Boc. Grades: >97%. CAS No. 1818294-42-6. Molecular formula: C27H55NO12. Mole weight: 585.73. | |
| Amino-PEG3-alcohol | 2-[2-(2-Aminoethoxy)ethoxy]ethanol (CAS# 6338-55-2) is a useful research chemical compound. Synonyms: 2-[2-(2-aminoethoxy)ethoxy]ethanol; 2-[2-(2-aminoethoxy)ethoxy]ethanol. Grades: >98%. CAS No. 6338-55-2. Molecular formula: C6H15NO3. Mole weight: 149.19. | |
| Amino-PEG3-t-butyl acetate | NH2-PEG3-C1-Boc is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 5 can be used in the synthesis of a series of PROTACs. NH2-PEG3-C1-Boc is a PEG derivative containing an amino group with a t-butyl protected carboxyl group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions. PEG Linkers may be useful in the development of antibody drug conjugates, PROTACs and drug delivery methods. Synonyms: NH2-PEG3-C1-Boc; PROTAC Linker 5; Amino-PEG3-CH2CO2-t-butyl ester; H2N-PEG3-CH2COOtBu; Acetic acid, 2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester. Grades: >95%. CAS No. 189808-70-6. Molecular formula: C12H25NO5. Mole weight: 263.33. | |
| Amino-PEG5-t-butyl Ester | Amino-PEG5-t-butyl Ester (CAS# 1446282-18-3) is a useful research chemical. Synonyms: Amino-PEG5-COOtBu; H2N-PEG5-CH2CH2COOtBu; 4,7,10,13,16-Pentaoxaoctadecanoic acid, 18-amino-, 1,1-dimethylethyl ester. Grades: >95%. CAS No. 1446282-18-3. Molecular formula: C17H35NO7. Mole weight: 365.46. | |
| Amino-PEG7-alcohol | Amino-PEG7-alcohol (CAS# 1425973-14-3) is a reagent used in pharmaceutical preparations such as the preparation of a water-soluble cancer vaccine adjuvant. Synonyms: 2- [2- [2- [2- [2- [2- (2-aminoethoxy) ethoxy] ethoxy] ethoxy] ethoxy] ethoxy] ethanol; 2- [2- [2- [2- [2- [2- (2-aminoethoxy) ethoxy] ethoxy] ethoxy] ethoxy] ethoxy] ethanol. Grades: >97%. CAS No. 1425973-14-3. Molecular formula: C14H31NO7. Mole weight: 325.40. | |
| Aminopotentidine | Aminopotentidine is a high selectivity and high affinity histamine H2 receptor antagonist. Its KB values are 220 and 280 nM at human and guinea pig H2 receptors respectively. It is the precursor for the synthesis of the [125I]-iodo derivative, so it can be used in the synthetic preparation of an iodo derivative. Synonyms: Benzamide, 4-amino-N- [2- [ [ (cyanoamino) [ [3- [3- (1-piperidinylmethyl) phenoxy] propyl] imino] methyl] amino] ethyl] -; 4-Amino-N- [2- [ [ (cyanoamino) [ [3- [3- (1-piperidinylmethyl) phenoxy] propyl] imino] methyl] amino] ethyl] benzamide; Benzamide, 4-amino-N- [2- [ [ (cyanoamino) [ [3- [3- (1-piperidinylmethyl) phenoxy] propyl] amino] methylene] amino] ethyl] -; 4-amino-N- (2- (3-cyano-2- (3- (3- (piperidin-1-ylmethyl) phenoxy) propyl) guanidino) ethyl) benzamide; 4-Amino-N-[2- (N'-cyano-N''-{3-[3- (1-piperidinylmethyl) phenoxy]propyl}carbamimidamido) ethyl]benzamide. Grades: ≥97% by HPLC. CAS No. 140873-26-3. Molecular formula: C26H35N7O2. Mole weight: 477.60. | |
| Aminopyrazine | Aminopyrazine (CAS# 5049-61-6) is a useful intermediate for organic synthesis and other chemical processes. Synonyms: pyrazin-2-amine. Grades: 95 %. CAS No. 5049-61-6. Molecular formula: C4H5N3. Mole weight: 95.10. | |
| Aminostilbamidine methanesulfonate salt | Aminostilbamidine methanesulfonate salt is a fluorescent cationic dye that is used for detecting DNA. Synonyms: ASBMS. CAS No. 1173097-67-0. Molecular formula: C18H25N5O6S2. Mole weight: 471.55. | |
| Aminotriester | Synonyms: AMINOTRIESTER; DENDRON P3; DI-TERT-BUTYL 4-AMINO-4-[2-(TERT-BUTOXYCARBONYL)ETHYL]HEPTANEDIOATE; DI-T-BUTYL 4-[2-(T-BUTOXYCARBONYL)ETHYL]-4-AMINOHEPTANEDICARBOXYLATE; DI-TERT-BUTYL 4-AMINO-4-[2- (TERT-BUTOXYCARBONYL) ETHYL]HEPTANEDIOATEDENDRON P3. Grades: 98%. CAS No. 136586-99-7. Molecular formula: C22H41NO6. Mole weight: 415.56. | |
| Amiodarone | Amiodarone, an iodine-rich benzofuran derivative, as a vaughan-Williams Class III antiarrhythmic agent it is an ATP-sensitive potassium channel inhibitor (IC50= 19.1 μM). Synonyms: (2-butyl-1-benzofuran-3-yl)-[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]methanone Alphapharm Brand of Amiodarone Hydrochloride Amiobeta Amiodarex Amiodarona Amiodarone Amiodarone Hydrochloride Amiohexal Aratac Armstrong Brand of Amiodarone Hydrochloride. Grades: ≥99%. CAS No. 1951-25-3. Molecular formula: C25H29I2NO3. Mole weight: 645.32. | |
| Amisulpride hydrochloride | Amisulpride hydrochloride could inhibit radioligand binding to native dopamine D2 receptor in membranes from the rat striatum with an IC50 value of 21nM. It has been revealed to displace [3H]raclopride binding in vivo with an ED50 value of 17.3±1.86mg/kg in the rat limbic system. It has been noted to inhibit quinpirole-induced [3H]thymidine with an IC50 value of 22±3nM. It is used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder. It has been approved in February 2002 by FDA. Uses: Amisulpride hydrochloride is used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder. Synonyms: DAN 2163 hydrochloride; DAN2163 hydrochloride; DAN-2163 hydrochloride; 4-amino-N-[(1-ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxybenzamide;hydrochloride. Grades: >98%. CAS No. 81342-13-4. Molecular formula: C17H28N3O4SCl. Mole weight: 405.94. | |
| Amitifadine hydrochloride | A Serotonin-Preferring Triple Reuptake Inhibitor for the Treatment of Major Depression, with the IC50 values for serotonin, norepinephrine and dopamine reuptake are 12/23/96 nM. Uses: A triple reuptake inhibitor (tri) or serotonin-norepinephrine-dopamine reuptake inhibitor (sndri). Synonyms: (1R, 5S)-1-(3, 4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane; hydrochloride; 1-(3,4-dichlorophenyl)-3-azabicyclo-(3.1.0)hexane hydrochloride. Grades: ≥98%. CAS No. 410074-74-7. Molecular formula: C11H12Cl3N. Mole weight: 264.57. | |
| Amlodipine EP Impurity A | Amlodipine EP impurity A is an impurity of Amlodipine. Amlodipine is a long-acting dihydropyridine L-type calcium channel blocker. Amlodipine is used to lower blood pressure and prevent chest pain. Synonyms: Amlodipine USP Related Compound D; Phthaloyl Amlodipine; phthalimidoamlodipine; Phthaloylamlodipine; 3-ethyl 5-methyl 4-(2-chlorophenyl)-2-((2-(1,3-dioxoisoindolin-2-yl)ethoxy)methyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate; 4-(2-Chlorophenyl)-2-[[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]methyl]-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic Acid 3-Ethyl 5-Methyl Ester. CAS No. 88150-62-3. Molecular formula: C28H27ClN2O7. Mole weight: 538.98. | |
| Ammonium benzoate | Synonyms: Benzoic acid, ammonium salt (1:1); Benzoic acid, ammonium salt; Vulnoc AB; Vulnoc ABS. Grades: ≥95%. CAS No. 1863-63-4. Molecular formula: C7H9NO2. Mole weight: 139.15. | |
| Ammonium citrate dibasic | Ammonium citrate dibasic (CAS# 3012-65-5) is a useful research chemical. Synonyms: azane;2-hydroxypropane-1,2,3-tricarboxylic acid. Grades: > 99 %. CAS No. 3012-65-5. Molecular formula: C6H14N2O7. Mole weight: 226.18. | |
| Ammonium diethyldithiocarbamate | Ammonium diethyldithiocarbamate (CAS# 21124-33-4 ) is a useful research chemical. Synonyms: azanium;N,N-diethylcarbamodithioate. Grades: 95 %. CAS No. 21124-33-4. Molecular formula: C5H14N2S2. Mole weight: 166.31. | |
| Ammonium iron(III) hexacyanoferrate(II) (Giese salt) | Synonyms: Ferric ammonium ferrocyanide. Grades: 95%. CAS No. 25869-00-5. Molecular formula: C6H4Fe2N7. Mole weight: 285.84. | |
| Ammonium iron(III) oxalate trihydrate | Ammonium iron(III) oxalate trihydrate (CAS# 13268-42-3) is used in preparation of complexed metal oxide catalysts for manufacture of ethylene by oxidative dehydrogenation of ethane. Grades: Purified. CAS No. 13268-42-3. Mole weight: 428.06. | |
| Ammonium metatungstate hydrate | Synonyms: Ammonium tungsten oxide hydrate; Hexaammonium wolframate hydrate. Grades: 0.9999. CAS No. 12333-11-8. Molecular formula: (NH4)6H2W12O40 · xH2O. Mole weight: 2956.3. | |
| Ammonium oxalate monohydrate | Synonyms: Ethanedioic acid, ammonium salt, hydrate (1:1:1); Ethanedioic acid, monoammonium salt, monohydrate; Ammonium bioxalate monohydrate; Ammonium oxalate, NH4C2HO4, hydrate. Grades: 95%. CAS No. 5972-73-6. Molecular formula: C2H2O4.H3N.H2O. Mole weight: 125.08. | |
| Ammonium Salicylate | Synonyms: AMMONIUM 2-HYDROXYBENZOATE; AMMONIUM SALICYLATE; Ai3-36572; Benzoic acid, 2-hydroxy-, ammonium salt; Einecs 250-553-9. Grades: Purity >98%. CAS No. 31295-34-8. Molecular formula: C7H9NO3. Mole weight: 155.15. | |
| Ammonium thiocyanate | Ammonium thiocyanate (CAS# 1762-95-4) is used in synthetic chemistry as a thiocyanation reagent. Ammonium thiocyanate is also a knwn plant poison and is used as a weed eradicant in the agricultural industry. Synonyms: azanium;thiocyanate. Grades: > 98.5 %. CAS No. 1762-95-4. Molecular formula: CH4N2S. Mole weight: 76.12. | |
| Ammonium thioglycolate solution | Ammonium thioglycolate solution (CAS# 5421-46-5) is a mucolytic that is used in many hair treating products (such as permanent wave products), and is also a known cause of allergic contact dermatitis to hairdressers constantly exposed to such products. Synonyms: azanium;2-sulfanylacetate. Grades: 95 %. CAS No. 5421-46-5. Molecular formula: C2H7NO2S. Mole weight: 109.15. | |
| AMN 082 dihydrochloride | The hydrochloride salt form of AMN 082 has been found to be a mGlu7 agonist. Synonyms: AMN 082; AMN-082; AMN082; N,N'-Bis(diphenylmethyl)-1,2-ethanediamine dihydrochloride. Grades: ≥99% by HPLC. CAS No. 97075-46-2. Molecular formula: C28H28N2.2HCl. Mole weight: 465.45. | |
| AMODIAQUINE | Amodiaquine is a drug which used to treat malaria, including Plasmodium falciparum malaria when uncomplicated. It has similar action to chloroquine. It is not available in the United States, but widely available in Africa. Uses: An antimalarial. Synonyms: 4-[(7-Chloro-4-quinolinyl)amino]-2-[(diethylamino)methyl]phenol; 4-[(7-Chloro-4-quinolyl)amino]-α-(diethylamino)-o-cresol; Camochin; Camoquin; Camoquinal; Camoquine; Flavoquine; Miaquin; NSC-13453; SN-10751; NSC 13453; SN 10751; NSC13453; SN10751. Grades: 95%. CAS No. 86-42-0. Molecular formula: C20H22ClN3O. Mole weight: 355.86. | |
| Amonafide L-malate | Amonafide L-malate is the malate salt of amonafide, an imide derivative of naphthalic acid, with potential antineoplastic activity. Amonafide intercalates into DNA and inhibits topoisomerase II, resulting in DNA double-strand breaks (DSB) and inhibition of DNA replication and RNA synthesis. Synonyms: AS1413; AS 1413; AS-1413; XLS-001; XLS001; XLS001; Xanafide. CAS No. 618863-60-8. Molecular formula: C20H24N4O6. Mole weight: 416.43. | |
| Amorolfine | Amorolfine is an antifungal used for the treatment of infections in fingernails or toenails. Synonyms: amorolfin; Amorolfinum; Amorolfina. Grades: 99%. CAS No. 78613-35-1. Molecular formula: C21H35NO. Mole weight: 317.51. | |
| Amorphous aluminum hydroxyphosphate sulfate | Amorphous aluminum hydroxyphosphate sulfate (AAHS) is an aluminum-containing adjuvant produced by Merck & Company (Rahway, NJ, USA), and is used in several commercial vaccines, including Recombivax, Gardasil, and Vaxelis. Synonyms: AAHS; aluminum hydroxyphosphate sulfate. CAS No. 150828-31-2. Molecular formula: AlHO9PS-3. Mole weight: 235.03. | |
| Amoxicillin Clavulanate | A broad-spectrum beta-lactam antibiotic. It is similar in structure to Ampicillin. Synonyms: Amoxicillin and clavulanic acid; Amoksiclav; Amoxyclav; Amoxicillin clavulanate acid; Amoxicillin mixture with Clavulanate; 4-Oxa-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3-(2-hydroxyethylidene)-7-oxo-, (2R,3Z,5R)-, mixt. with (2S,5R,6R)-6-(((2R)-amino(4-hydroxyphenyl)acetyl)amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid. Grades: Amoxicillin: ≥54.0%; Clavulanic Acid: ≥26.8%. CAS No. 79198-29-1. Molecular formula: C24H28N4O10S. Mole weight: 564.56. | |
| AMPA/kainate antagonist-1 | AMPA/kainate antagonist-1 is a non-competitive AMPA/kainate antagonist. Synonyms: (r)-(+)-8-methyl-5-(3-methyl-4-nitrophenyl)-8,9-dihydro-7h-1,3-dioxolo[4,5-h][2,3]benzodiazepine. Grades: 98%. CAS No. 732277-05-3. Molecular formula: C18H17N3O4. Mole weight: 339.3. | |
| AMPA/Kainate Antagonist-2 | AMPA/kainate antagonist-2 is a non-competitive AMPA/kainate antagonist. Synonyms: AMPA/kainate antagonist-2; 923271-87-8; AMY40928BCP34146(+)-5-(4-amino-3-methylphenyl)-7-(2-thiazolyl)-8,9-dihydro-7H-1,3-dioxolo-[4,5-h][2,3]benzodiazepine. Grades: 98%. CAS No. 923271-87-8. Molecular formula: C20H18N4O2S. Mole weight: 378.4. | |
| AMPA/kainate antagonist-3 | AMPA/kainate antagonist-3 is a non-competitive AMPA/kainate antagonist. Grades: 98%. CAS No. 732278-52-3. Molecular formula: C21H21N5O2S. Mole weight: 407.5. | |
| Ampalex | CX516 is a positive allosteric modulator at AMPA receptor that inhibits the deactivation of AMPA receptors. CX-516 is a nootropic and ampakine agent. Synonyms: CX-516; CX 516; CX516; BDP 12; BDP-12; BDP12; SPD-420; SPD420; brand name: Ampalex. Grades: >98%. CAS No. 154235-83-3. Molecular formula: C14H15N3O. Mole weight: 241.29. | |
| Ampicillin EP Impurity C | An impurity of Ampicillin, an antibiotic used for the treatment of various bacterial infections. Synonyms: Diketopiperazines of ampicillin. Molecular formula: C16H19N3O4S. Mole weight: 349.40. | |
| Ampicillin EP Impurity F (2S-Isomer) | An impurity of Ampicillin, an antibiotic used for the treatment of various bacterial infections. Synonyms: 4-Thiazolidinecarboxylic acid, 2-[[(aminophenylacetyl)amino]methyl]-5,5-dimethyl-, [2S-[2α(S*),4α]]-. CAS No. 124774-49-8. Molecular formula: C15H21N3O3S. Mole weight: 323.41. | |
| Ampicillin EP Impurity M | An impurity of Ampicillin, an antibiotic used for the treatment of various bacterial infections. Synonyms: co-oligomers of ampicillin and of penicilloic acids of ampicillin. | |
| Ampicillin EP Impurity N | An impurity of Ampicillin, an antibiotic used for the treatment of various bacterial infections. Synonyms: (3S)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-2,2-dimethyl-7-oxo-2,3,4,7-tetrahydro-1,4-thiazepine-3-carboxylic acid. Molecular formula: C16H19N3O4S. Mole weight: 349.40. | |
| Ampicillin oligomer 1 (dimer) | An impurity of Ampicillin, an antibiotic used for the treatment of various bacterial infections. Molecular formula: C32H38N6O8S2. Mole weight: 698.81. | |
| Ampicillin oligomer 1 (trimer) | An impurity of Ampicillin, an antibiotic used for the treatment of various bacterial infections. CAS No. 114977-84-3. Molecular formula: C48H57N9O12S3. Mole weight: 1048.21. | |
| Ampicillin oligomer 2 | An impurity of Ampicillin, an antibiotic used for the treatment of various bacterial infections. Molecular formula: C32H40N6O9S2. Mole weight: 716.82. | |
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