BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Phenylpropyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranoside | Phenylpropyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranoside, also known as PTAG, stands as a remarkable biomedicine employed for multifarious ailments. Its bioactivity holds substantial potential for drug synthesis targeting bacterial infections, inflammation, and associated disorders. Remarkably intricate in its chemical composition, this compound unveils a plethora of compelling antimicrobial and anti-inflammatory attributes. Synonyms: Phenylpropyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranoside; [(2R,3S,4R,5R,6R)-5-acetamido-3,4-diacetyloxy-6-(3-phenylpropoxy)oxan-2-yl]methyl acetate; DTXSID70585910; AKOS025294929; PHENYLPROPYL 2-ACETAMIDO-3,4,6-TRI-O-ACETYL-2-DEOXY-BETA-D-GLUCOPYRANOSIDE; W-201908; 3-Phenylpropyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-beta-D-glucopyranoside. CAS No. 220341-05-9. Molecular formula: C23H31NO9. Mole weight: 465.49. |  |
| Phloridzin | Cas No. 7061-54-3. | |
| Phloridzin hydrate | | |
| Phortress | Phortress, a lysyl amide prodrug of the benzothiazole 5-fluoro 203, is an apoptosis stimulant potentially for the treatment of solid tumours. Phortress had no effect on HUVEC and MRCV cell proliferation and survival. Unlike paclitaxel and fumagillin, Phortress did not inhibit endothelial tube differentiation. Synonyms: (2S)-2,6-Diamino-N-[4-(5-fluoro-2-benzothiazolyl)-2-methylphenyl]hexanamide dihydrochloride; Phortress; NSC 710305; NSC710305; NSC-710305; 5F-DF-203-L-lysinamide; 5FDF 203Llysinamide. Grades: ≥98% by HPLC. CAS No. 328087-38-3. Molecular formula: C20H23FN4OS.2HCl. Mole weight: 459.41. | |
| Phosphatidyl 1-(D-2,3-dideoxy-myo-inositol) | Phosphatidyl 1-(D-2,3-dideoxy-myo-inositol) is an essential biomolecule, finding widespread application in cellular signaling cascades and lipid metabolic pathways. It is revered for its multifaceted role in studying lipid disorders, diabetes and neurodegenerative ailments. CAS No. 701976-55-8. Molecular formula: C28H57O9P. Mole weight: 568.72. | |
| Phosphatidyl inositol - 10mg/ml solution in chloroform:methanol(4:1) | Phosphatidyl inositol is a meticulous and concentrated concoction boasting an impressive 10mg/ml density within a chloroform:methanol (4:1) concoction, exclusively formulated to align with the stringent requirements of the biomedical sector. Molecular formula: C47H83O13P. Mole weight: 887.13. | |
| Phosphoramidon Disodium Salt | Phosphoramidon is a powerful inhibitor of thermolysin without inhibiting the other endopeptidases such as trypsin, papain, chymotrypsin. Synonyms: N-(alpha-Rhamno-pyranosyl-phos-phono)-L-leucyl-L-tryptophan disodium salt; L-Tryptophan, N- ( ( (6-deoxy-alpha-L-mannopyranosyl) oxy) hydroxyphosphinyl) -L-leucyl-, disodium salt. Grades: >98%. CAS No. 164204-38-0. Molecular formula: C23H32N3Na2O10P. Mole weight: 587.47. | |
| Phosphoric acid mono-((2R,3R,4S,5R)-2,3,4,5,7-pentahydroxy-6-hydroxyimino-heptyl) ester disodium salt (compound H) | Compound H, known as phosphoric acid mono-((2R,3R,4S,5R)-2,3,4,5,7-pentahydroxy-6-hydroxyimino-heptyl) ester disodium salt is a prominent biomedical compound in the research of specific ailments. Molecular formula: C7H14O10NPNa2. Mole weight: 349.14. | |
| Photochlor | Photochlor, also known as HTTP, is a lipophilic, second-generation, chlorin-based photosensitizer. Upon intravenous administration, HPPH selectively accumulates in the cytoplasm of cancer or pre-cancerous cells. When laser light is applied, a photodynamic reaction between HPPH and oxygen occurs, resulting in the production of cytotoxic free radicals and singlet oxygen and free radical-mediated cell death. Compared to the first-generation photosensitizer porfimer sodium, HPPH shows improved pharmacokinetic properties and causes only mild skin photosensitivity which declines rapidly within a few days after administration. Synonyms: HPPH; 2-(1-Hexyloxyethyl)-2-devinyl pyropheophorbide-a; 14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbinepropanoic acid. Grades: >98%. CAS No. 149402-51-7. Molecular formula: C39H48N4O4. Mole weight: 636.83. | |
| PHY34 | PHY34 is an autophagy inhibitor with nanomolar potency. It exhibits potent cytotoxic activity against high-grade serous ovarian cancer (HGSOC) cells via activation of apoptosis. Synonyms: 4-[[(3aR,4S,6R,7S,7aS)-7-hydroxy-4-(hydroxymethyl)-2,2-dimethyl-4,6,7,7a-tetrahydro-3aH-[1,3]dioxolo[4,5-c]pyran-6-yl]oxy]-9-(1,3-benzodioxol-5-yl)-3H-benzo[f][2]benzofuran-1-one. CAS No. 2130033-55-3. Molecular formula: C30H30O12. Mole weight: 582.55. | |
| Physostigmine hemisulfate | Physostigmine hemisulfate, a derivative of Physostigmine, is a parasympathomimetic, specifically, a reversible cholinesterase inhibitor. Synonyms: (3aS)-cis-1,2,3,3a,8,8a-Hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indol-5-ol methylcarbamate hemisulfate; Eserine sulfate; physostigmine sulfate. Grades: ≥98% by HPLC. CAS No. 64-47-1. Molecular formula: C15H21N3O2.1/2H2SO4. Mole weight: 324.39. | |
| Pifithrin-β hydrobromide | Pifithrin-β hydrobromide is a reversible inhibitor of p53-dependent transcription and apoptosis, inhibits the growth of the cancer cell lines IGROV-1 (IC50 = 23 μM). Uses: Inhibits the growth of the cancer cell lines igrov-1, a2780, and hct116. Synonyms: Cyclic Pifithrin-alpha Hydrobromide; 2-(4-methylphenyl)-5,6,7,8-tetrahydroimidazo[2,1-b][1,3]benzothiazole;hydrobromide. Grades: ≥98%. CAS No. 511296-88-1. Molecular formula: C16H17BrN2S. Mole weight: 349.29. | |
| Pifithrin-mu | Pifithrin-mu is an inhibitor of p53-mediated apoptosis, preventing p53 binding to Bcl-xL (Kd = 0.82 mM) and Bcl-2 (Kd = 0.80 mM). Pifithrin-mu enhances reprogramming of human somatic cells to induced pluripotent stem cells (iPSCs) via silencing p53. Synonyms: Pifithrin-μ; phenylethynesulfonamide; Pifithrin-micro; NSC 303580. Grades: >98%. CAS No. 64984-31-2. Molecular formula: C8H7NO2S. Mole weight: 181.21. | |
| PIK-124 | PIK-124 is a potent PI3K inhibitor. Synonyms: PIK124; PIK 124; (E)-4-(3-chloro-4-fluorobenzyl)-6-((4-oxo-2-thioxothiazolidin-5-ylidene)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one. Grades: 98%. CAS No. 711025-68-2. Molecular formula: C19H12ClFN2O3S2. Mole weight: 434.89. | |
| PIK-293 | PIK-293 is a PI3K inhibitor, mostly for PI3Kδ with IC50 of 0.24 μM, 500-, 100- and 50-fold less potent to PI3Kα/β/γ, respectively. Synonyms: PIK 293; PIK293; 2-((4-amino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)-5-methyl-3-o-tolylquinazolin-4(3H)-one. Grades: >98%. CAS No. 900185-01-5. Molecular formula: C22H19N7O. Mole weight: 397.43. | |
| PIK-39 | PIK-39 is a potent PI3K inhibitor. Synonyms: PIK 39; PIK39; 2-(((9H-purin-6-yl)thio)methyl)-5-chloro-3-(2-methoxyphenyl)quinazolin-4(3H)-one. Grades: 98%. CAS No. 371242-53-4. Molecular formula: C21H15ClN6O2S. Mole weight: 450.90. | |
| Pimonidazole | Pimonidazole, also known as Ro 03-8799 and PD 126675, is a nitroimidazole drug with hypoxic selectivity and radiosensitizing property. Pimonidazole is reduced in hypoxic environments as in tumor cells, thereby it can be used as an hypoxia marker. In hypoxic cells, reduced pimonidazole binds to -SH-containing molecules such as glutathione and proteins, and the resulting complexes accumulated in tissues, thereby sensitizing cells to be more susceptible for radiation treatment. Synonyms: NSC 380540; NSC-380540; NSC380540; PD 126675; PD126675; PD-126675; Ro 03-8799. Grades: >98%. CAS No. 70132-50-2. Molecular formula: C11H18N4O3. Mole weight: 254.29. | |
| Pimozide | Pimozide is a diphenylbutylpiperidine derivative and a dopamine antagonist with antipsychotic property. Pimozide selectively inhibits type 2 dopaminergic receptors in the central nervous system (CNS), and also inhibits STAT3 and STAT5. Uses: Anti-dyskinesia agents. Synonyms: R6238. Grades: 98%. CAS No. 2062-78-4. Molecular formula: C28H29F2N3O. Mole weight: 461.55. | |
| Pinatuzumab | Pinatuzumab is an anti-CD22 monoclonal antibody which has been used in the research of non-Hodgkin lymphoma (NHL). CAS No. 1639820-81-7. | |
| Pinitol diacetonide | Pinitol diacetonide, an intriguing biomedical compound with immense therapeutic potential, unveils its applicability in combating multifarious ailments including diabetes, cancer, and inflammation. Deriving from the naturally occurring pinitol, abundantly present in plants, this compound manifests remarkable pharmacological attributes. Its profound properties make it an indispensable component for pioneering therapeutic advances addressing these adversities. Synonyms: Di-O-isopropylidene-D-pinitol. CAS No. 57819-56-4. Molecular formula: C13H22O6. Mole weight: 274.31. | |
| Pipendoxifene | Pipendoxifene, also known as ERA-923, is a new antiestrogen with potential anticancer activity. ERA-923 potently inhibits estrogen binding to ER-alpha (IC50=14 nM). In ER-alpha-positive human MCF-7 breast carcinoma cells, ERA-923 inhibits estrogen-stimulated growth (IC50=0.2 nM) associated with cytostasis. In vitro, a MCF-7 variant with inherent resistance to tamoxifen (10-fold) or 4-OH tamoxifen (>1000-fold) retains complete sensitivity to ERA-923. In preclinical models, ERA-923 has an improved efficacy and safety compared with tamoxifen. In the combination with temsirolimus, ERA-923 showed excellent anticancer activity in preclinical models. Synonyms: ERA-923; ERA 923; ERA923; 2-(p-Hydroxyphenyl)-3-methyl-1-(p-(2-piperidinoethoxy)benzyl)indol-5-ol. Grades: >98%. CAS No. 198480-55-6. Molecular formula: C29H32N2O3. Mole weight: 456.58. | |
| Piroxantrone | Piroxantrone is an anthrapyrazole antineoplastic antibiotic. Piroxantrone intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. Although less cardiotoxic than doxorubicin, this agent exhibits a narrow spectrum of antineoplastic activity. Synonyms: oxanthrazole; oxantrazole; Piroxantrone HCl; PD-111815; PD 111815; PD111815. CAS No. 91441-23-5. Molecular formula: C21H25N5O4. Mole weight: 411.46. | |
| Pitavastatin 3-O-Glucuronide | A metabolite of Pitavastatin which is a Hydroxymethylglutaryl-CoA reductase inhibitor. Grades: > 95%. Molecular formula: C31H31FNO10. Mole weight: 596.58. | |
| Pivanex | Pivanex, also known as AN-9, is a histone deacetylase inhibitor analog of butyric acid that causes apoptosis of cancer cells through signaling cellular differentiation. AN-9 exerts a significant anticancer activity in vitro and in vivo. Synonyms: AN-9; AN 9; AN9; pivaloyloxymethyl butyrate; Titan. CAS No. 122110-53-6. Molecular formula: C10H18O4. Mole weight: 202.25. | |
| Pivekimab | Pivekimab is a human anti-IL-3 monoclonal antibody. Pivekimab can be used in the synthesis of ADC Pivekimab sunirine, which is developed for the treatment of hematological malignancies. CAS No. 2234335-84-1. | |
| PKI-179 | PKI-179 is a second generation, small-molecule mimetic of ATP that targets the mammalian target of rapamycin (mTOR) with potential antineoplastic activity. PKI-179 selectively inhibits mTOR and phosphoinositide-3-kinase (PI3K) alpha. By inhibiting the PI3K/mTOR signaling pathway, this agent may inhibit tumor cell proliferation and survival. Synonyms: PKI-179; PKI 179; PKI179. Grades: ≥98%. CAS No. 1197160-28-3. Molecular formula: C25H28N8O3. Mole weight: 488.55. | |
| Plevitrexed | Plevitrexed is an orally bioavailable, small molecule, non-polyglutamatable, antifolate quinazoline derivative thymidine synthetase inhibitor with potential antineoplastic activity. Plevitrexed is transported into the cell via the physiological reduced folate carrier (RFC) system. Intracellularly, this agent selectively binds to the folate binding site of thymidylate synthase and inhibits thymidine synthesis, which may result in DNA synthesis inhibition and apoptosis. Uses: Antineoplastic agents. Synonyms: ZD 9331; BGC9331; (αS)-α-[[4-[[(1,4-Dihydro-2,7-dimethyl-4-oxo-6-quinazolinyl)methyl]-2-propynylamino]-2-fluorobenzoyl]amino]-1H-tetrazole-5-butanoic Acid; NSC 696259; Vamidex; (2S)-2-((4-(((2,7-Dimethyl-4-oxo-1,4-dihydroquinazolin-6-yl)methyl)(prop-2-ynyl)amino)-2-fluorobenzoyl)amino)-4-(1H-tetrazol-5-yl)butanoic acid. Grades: ≥95%. CAS No. 153537-73-6. Molecular formula: C26H25FN8O4. Mole weight: 532.53. | |
| PluriSln 1 | PluriSln 1 is an inhibitor of stearoyl-CoA desaturase 1 (SCD1). It is useful for eliminating undifferentiated human pluripotent stem cells (hPSCs) from culture by selectively inducing apoptosis in these cells. Additionally, pluriSln 1 induces endoplasmic reticulum stress, reduces protein synthesis, and prevents teratoma formation in immunocompromised mice models. Synonyms: N'-phenylisonicotinohydrazide; N'-phenylpyridine-4-carbohydrazide. Grades: >98%. CAS No. 91396-88-2. Molecular formula: C12H11N3O. Mole weight: 213.24. | |
| p-Methoxyphenyl 1-thio-b-D-galactopyranoside | p-Methoxyphenyl 1-thio-b-D-galactopyranoside is an indispensable biochemical compound, serving as a substrate renowned for its exceptional efficacy in identifying and characterizing diverse enzyme activities implicated in carbohydrate metabolism. CAS No. 41341-62-2. | |
| p-Methoxytopolin-9-glucoside | p-Methoxytopolin-9-glucoside is an intriguing and compelling bioactive compound, extensively utilized in studying disorders associated with oxidative stress and inflammation. Molecular formula: C19H23N5O6. Mole weight: 417.42. | |
| PND-1186 | Cas No. 1356154-94-3. | |
| p-Nitrophenyl 2-Acetamido-2-deoxy-α-D-galactopyranoside | p-Nitrophenyl 2-Acetamido-2-deoxy-α-D-galactopyranoside is an essential compound in biomedicine. It is commonly utilized in the production of synthetic substrates for studying glycosidase enzymes. This compound is valuable in research concerning carbohydrate chemistry, specifically in the investigation of enzymes involved in breaking down glycosylation processes. It plays a crucial role in medicinal chemistry by aiding in the development of drugs targeting certain diseases related to carbohydrate processing and glycosylation disorders. Synonyms: 4-Νitrophenyl 2-(acetylamino)-2-deoxy-α-D-galactopyranoside; p-Nitrophenyl N-acetyl-α-D-galactosaminoside; p-Nitrophenyl-α-N-acetylgalactosamine;GalNAc-α-PNP. Grades: 98%. CAS No. 23646-68-6. Molecular formula: C14H18N2O8. Mole weight: 342.3. | |
| p-Nitrophenyl 2-Azido-2-deoxy-β-D-galactopyranoside | p-Nitrophenyl 2-Azido-2-deoxy-β-D-galactopyranoside is a prominent biochemical compound, extensively utilized as a glycosidase substrate, facilitating the detection of glycosidases in enzymatic studies. Grades: 98%. Molecular formula: C12H14N4O7. Mole weight: 326.26. | |
| PNU 74654 | PNU 74654 inhibits the Wnt-β catenin pathway by blocking the interaction between β-catenin and TCF (T cell factor). Treatment of human adrenocortical cell lines with PNU 74654 significantly reduced expression of several Tcf/β-catenin target genes. Synonyms: PNU 74654; PNU-74654; PNU74654; 2-Phenoxybenzoic acid-[(5-methyl-2-furanyl)methylene]hydrazide. Grades: ≥99% by HPLC. CAS No. 113906-27-7. Molecular formula: C19H16N2O3. Mole weight: 320.34. | |
| Podophyllotoxin-4-O-glucoside | source from rhizoma podophylli emodi. Uses: Antineoplastic. Synonyms: Podophyllotoxin 7'-O-beta-D-glucopyranoside; (5R,5aR,8aR,9R)-9-(beta-D-Glucopyranosyloxy)-5,8,8a,9-tetrahydro-5-(3,4,5-trimethoxyphenyl)-furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one. Grades: >98%. CAS No. 16481-54-2. Molecular formula: C28H32O13. Mole weight: 576.55. | |
| Polatuzumab | Polatuzumab is a monoclonal antibody directed against CD79b, which is ubiquitously expressed on the surface of malignant B cells. Polatuzumab can be used in the synthesis of polatuzumab vedotin, an ADC indicated in combination with bendamustine and a rituximab product for adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). CAS No. 2279068-37-8. | |
| Poloxipan | Poloxipan is a potent and pan-specific PLK1 inhibitor. In vitro, Poloxipan has IC50 3.2 uM (Plk1); 1.7 uM (Plk2); and 3 uM (Plk3). Poloxipan showed minor inhibition over FHA dommain of Chk2, S2 domian of STAT1, STAT5b, Lck, etc. Synonyms: (Z)-2-(5-bromo-2-methoxybenzylidene)-6-methyl-2H-thiazolo[3,2-b][1,2,4]triazine-3,7-dione; 2-(5-Bromo-2-methoxybenzylidene)-6-methyl-2H-thiazolo[3,2-b][1,2,4]triazine-3,7-dione. Grades: 98%. CAS No. 1239513-63-3. Molecular formula: C14H10BrN3O3S. Mole weight: 380.22. | |
| Polydatin | Polydatin is a crystal component extracted from the root stem of perennial herbage Polygonum Cuspidatum Sieb.et Zucc. It is an inhibitor of platelet aggregation. Synonyms: Piceid; Trans-Piceid; 3,4,5-Tsg; 3,4,5-Trihydroxystilbene-3-beta-monoglucoside; (E/Z)-Polydatin; Resveratrol 3-O-b-D-glucopyranoside. Grades: >98%. CAS No. 65914-17-2. Molecular formula: C20H22O8. Mole weight: 390.38. | |
| Polygalacturonic acid sodium | Polygalacturonic acid sodium is a bioactive compound widely employed in the biomedical sector, exhibiting remarkable efficacy in studying diverse pathological ailments encompassing inflammation, malignancies and viral affections. Synonyms: Sodium polypectate; Polyanhydrogalacturonic acid. CAS No. 9049-37-0. | |
| Polysucrose | Polysucrose is a highly versatile biocompatible polymer extensively utilized as a stabilizer and excipient for pharmaceutical and vaccine formulations. It is esteemed for its exceptional biocompatibility and solubility attributes. Synonyms: Alpha-D-Fructofuranosyl Alpha-D-Glucopyranoside; SWE; SCHEMBL365357; (2R,3R,4S,5S,6R)-2-[(2R,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol; Q27465514. CAS No. 25702-74-3. Molecular formula: C12H22O11. Mole weight: 342.30. | |
| Polysucrose 400 | Polysucrose 400 is a crucial compound product, used for studying diverse ailments including diabetes and cancer. Synonyms: 2-(chloromethyl)oxirane; (2R,3R,4S,5S,6R)-2-[(2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol; SCHEMBL8603704; Sucrose-epichlorohydrin copolymer; AKOS040757967; A852961; |A-D-Glucopyranoside, |A-D-fructofuranosyl, polymer with 2-(chloromethyl)oxirane. CAS No. 26873-85-8. Molecular formula: C15H27ClO12. Mole weight: 400K. | |
| Ponezumab | Ponezumab is a humanized anti-amyloid monoclonal antibody. Ponezumab has been used in the research of Alzheimer's disease. Synonyms: PF-04360365; PF 04360365; PF04360365. CAS No. 1178862-65-1. | |
| Ponsegromab | Ponsegromab is a humanized anti-GDF15 monoclonal antibody with potential anti-cachexia activity. Ponsegromab binds to GDF15, thereby preventing the binding of GDF15 to its receptor glial-cell-derived neurotrophic factor (GDNF) family receptor alpha-like (GFRAL) and blocking GDF15/GFRAL-mediated signaling. Synonyms: PF 06946860. CAS No. 2368950-15-4. | |
| Populin | Populin is an organic compound derived from the bark of Populus tremula, aiding in studying diverse inflammatory ailments such as arthritand asthma. Synonyms: 6-Benzoylsalicin; Populoside. CAS No. 99-17-2. Molecular formula: C20H22O8. Mole weight: 390.38. | |
| Porfimer Sodium | Porfimer sodium is the sodium salt of a mixture of oligomers formed by ether and ester linkages of up to eight porphyrin units with photodynamic activity. It is a photosensitizer used in photodynamic therapy and radiation therapy and for palliative treatment of obstructing endobronchial non-small cell lung carcinoma and obstructing esophageal cancer. Synonyms: Dihematoporphyrin Ether; Photofrin. Grades: >98%. CAS No. 97067-70-4. Molecular formula: C68H74N8O11. Mole weight: 1179.36. | |
| Potassium Channel Activator 1 | A potassium channel activator used for the treatment of one or more disorders or conditions wherein the dopaminergic system is disrupted. Synonyms: (2,4-Dimethyl-6-morpholin-4-yl-pyridin-3-yl)-carbamic acid benzyl ester. CAS No. 908608-06-0. Molecular formula: C19H23N3O3. Mole weight: 341.4. | |
| Potassium D-erythronate | Potassium D-erythronate: An intricate biomedical formulation synthesized from D-erythronate, integrating the crucial element of potassium. Its principal application lies in mitigating insufficiencies linked to potassium levels within the corporeal framework. By reinstating the depleted potassium reserves, it optimizes and upholds the harmonious functionality of vital bodily processes, while also ensuring equilibrium in electrolyte dynamics. Synonyms: 2,3,4-Trihydroxybutanoic acid potassium salt. CAS No. 88759-55-1. Molecular formula: C4H7KO5. Mole weight: 174.19. | |
| PP1 | PP1 is a potent, reversible, ATP-competitive, and selective inhibitor of the Src family of protein tyrosine kinases. It inhibits p56lck (IC50 = 5 nM), p59fynT (IC50 = 6 nM), Hck (IC50 = 20 nM), and Src (IC50 = 170 nM) without significantly affecting the activity of EGFR kinase (IC50 = 250 nM), JAK2 (IC50 = 50 μM), or ZAP-70 (IC50 ≥ 0.6 μM). Synonyms: PP1; PP 1; PP1. Grades: >98%. CAS No. 172889-26-8. Molecular formula: C16H19N5. Mole weight: 281.36. | |
| PPI-2458 | PPI-2458 is a synthetic derivative of fumagillin with antineoplastic and cytotoxic properties. PPI-2458 irreversibly inhibits the enzyme methionine aminopeptidase type 2 (MetAP2), thereby preventing abnormal cell growth and angiogenesis. PPI-2458 is reported to have a better toxicity profile compared to other agents of its class. Synonyms: PPI 2458; PPI2458; Metapro; NSC-720735. CAS No. 431077-35-9. Molecular formula: C22H36N2O6. Mole weight: 424.54. | |
| PPOH | PPOH is a selective inhibitor of the epoxygenation reactions catalyzed by specific CYP450 isozymes. Synonyms: 6-(2-propargyloxyphenyl)hexanoic acid. Grades: ≥99%. CAS No. 206052-01-9. Molecular formula: C15H18O3. Mole weight: 246.3. | |
| PPP hydrochloride | PPP hydrochloride is a selective inactivator of human cytochrome P450 2B6 (CYP2B6). Synonyms: 1-(2-phenylpropan-2-yl)piperidine hydrochloride; 1-(alpha,alpha-Dimethylbenzyl)piperidine hydrochloride. Grades: 99%. CAS No. 21602-56-2. Molecular formula: C14H21N.HCl. Mole weight: 239.78. | |
| PR-104 | PR-104 is a non-toxic, small-molecule, hypoxia-activated, 3,5-dinitrobenzamide nitrogen mustard pre-prodrug with potential antitumor activity. Upon intravenous administration, PR-104 is converted by systemic phosphatases to the alcohol intermediate PR-104A, which is reduced to form the active DNA-crosslinking mustard species hydroxylamine PR-104H intracellularly under hypoxic conditions. PR-104H specifically crosslinks hypoxic tumor cell DNA, resulting in the inhibition of DNA repair and synthesis, cell-cycle arrest, and apoptosis in susceptible hypoxic tumor cell populations while sparing normoxic tissues. Synonyms: PR 104; PR104; 2- ( (2-Bromoethyl) (2, 4-dinitro-6- ( (2- (phosphonooxy) ethyl) carbamoyl) phenyl) amino) ethyl methanesulfonate; Benzamide, 2-[(2-bromoethyl)[2-[(methylsulfonyl)oxy]ethyl]amino]-3,5-dinitro-N-[2-(phosphonooxy)ethyl]-. Grades: ≥97%. CAS No. 851627-62-8. Molecular formula: C14H20BrN4O12PS. Mole weight: 579.27. | |
| Prednimustine | Prednimustine is a drug used in chemotherapy. It is the ester formed from two other drugs, prednisolone and chlorambucil. Prednimustine probably kills rapidly growing cells by modifying cell's DNA with a chemical structure called an alkyl group. Uses: Antineoplastic agents, alkylating. Synonyms: LEO 1031; LEO1031; LEO-1031; Stereocyt; NSC-134087; (11beta)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl 4-{4-[bis(2-chloroethyl)amino]phenyl}butanoate; NSC-171345; BRN 2826967. Grades: >98%. CAS No. 29069-24-7. Molecular formula: C35H45Cl2NO6. Mole weight: 646.65. | |
| Pregnanediol 3a-O-b-D-glucuronide | Pregnanediol 3a-O-b-D-glucuronide, an indispensable biomarker in the field of biomedicine, serves as a crucial diagnostic and monitoring tool for hormonal diseases. By reflecting the metabolic pathways of progesterone, this compound enables the assessment of hormonal imbalances and the evaluation of therapeutic interventions. In biomedical research and clinical environments, its significance lies in facilitating the accurate detection of diseases and the evaluation of treatment effectiveness. Synonyms: (3a,5b,20S)-20-Hydroxypregnan-3-yl b-D-glucopyranosiduronic acid; 20a-Hydroxy-5b-pregnan-3a-yl b-D-glucopyranosiduronic acid; 5b-Pregnane-3a,20a-diol glucuronide. CAS No. 1852-49-9. Molecular formula: C27H44O8. Mole weight: 496.63. | |
| Pregnanediol 3a-O-b-D-glucuronide BSA conjugate | | |
| Pregnanetriol 3a-O-b-D-glucuronide | Pregnanetriol 3a-O-b-D-glucuronide is a prominent biomarker extensively utilized within the biomedical industry, holding paramount significance in studying bile acid metabolic status. Profoundly implicated in the research of liver ailments, encompassing cholestasand hepatocellular carcinoma, this compound assumes a pivotal role. Synonyms: (3a,5b,20S)-17,20-Dihydroxypregnan-3-yl b-D-glucopyranosiduronic acid; 17,20a-Dihydroxy-5b-pregnan-3a-yl, b-D-glucopyranosiduronic acid. CAS No. 74915-85-8. Molecular formula: C27H44O9. Mole weight: 512.63. | |
| Prinomastat | Prinomastat is a synthetic hydroxamic acid derivative with potential antineoplastic activity. Prinomastat inhibits matrix metalloproteinases (MMPs) (specifically, MMP-2, 9, 13, and 14), thereby inducing extracellular matrix degradation, and inhibiting angiogenesis, tumor growth and invasion, and metastasis. As a lipophilic agent, prinomastat crosses the blood-brain barrier. Uses: Matrix metalloproteinase inhibitors. Synonyms: AG3340; AG-3340; AG 3340; KBR-9896; KBR 9896; KBR9896. CAS No. 192329-42-3. Molecular formula: C18H21N3O5S2. Mole weight: 423.50. | |
| Proadifen Hydrochloride | Proadifen hydrochloride is a Cytochrome P450 inhibitor (IC50 = 19μM) and stimulate endothelial cell prostacyclin production. Uses: Cytochrome p-459 inhibitor; blocks glibenclamide-sensitive k+ channels. Synonyms: 2-(diethylamino)ethyl 2,2-diphenylpentanoate;hydrochloride;SKF-525A, Hydrochloride; Proadifen hydrochloride; NSC 170997; NSC-170997; NSC170997. Grades: ≥98%. CAS No. 62-68-0. Molecular formula: C23H32ClNO2. Mole weight: 389.96. | |
| Probenecid Acyl β-D-Glucuronide | A metabolite of Probenecid. Probenecid is a medication that increases uric acid excretion in the urine. Probenecid can be used in treating gout and hyperuricemia. Synonyms: 1-[4-[(Dipropylamino)sulfonyl]benzoate]. Grades: > 95%. CAS No. 34017-15-7. Molecular formula: C19H27NO10S. Mole weight: 461.48. | |
| Procarbazine Hydrochloride | Procarbazine Hydrochloride is an alkylating agent, with anticancer activity. Synonyms: Ibenzmethyzin; ibenzmethyzin hydrochloride; ibenzmethyzine hydrochloride; MIH; MIH hydrochloride; PCB Hydrochloride; PCZ; Procarbazin. Matulane. Natulan; Natulanar; Natunalar. PCB; PCZ. NCI-C01810; Ro 4-6467/1. Grades: >98%. CAS No. 366-70-1. Molecular formula: C12H20ClN3O. Mole weight: 257.762. | |
| Promethazine N-β-D-Glucuronide | A metabolite of Promethazine. Promethazine is a neuroleptic medication and first-generation antihistamine of the phenothiazine family. It has strong sedative and weak antipsychotic effects. Synonyms: N-b-D-Glucopyranuronosyl-N,N,a-trimethyl-10H-phenothiazine-10-ethanaminium inner salt; Promethazine N-glucuronide. Grades: > 95%. CAS No. 137908-81-7. Molecular formula: C23H28N2O6S. Mole weight: 460.54. | |
| Propargyl 2,3,4,6-tetra-O-acetyl-b-D-galactopyranoside | Propargyl 2,3,4,6-tetra-O-acetyl-b-D-galactopyranoside is a crucial compound used as a substrate for enzymes involved in carbohydrate metabolism and glycosylation processes. It finds application in the synthesis of complex carbohydrates and investigations regarding the role of glycans in disease progression, such as cancer and neurodegenerative disorders. Synonyms: Propargyl 2,3,4,6-tetra-O-acetyl-b-D-galactopyranoside; SCHEMBL17784269; HKGFUJKLPCRVFW-DRRXZNNHSA-N; propargyl 2,3,4,6-tetra-O-acetyl-beta-D-galactopyranoside. Molecular formula: C17H22O10. Mole weight: 386.3. | |
| Propargyl a-D-glucopyranoside | Propargyl α-D-glucopyranoside is an invaluable compound harnessed in the ambit of biomedical exploration assuming as a precursor for engendering glycosides and modified carbohydrates. It is used in studying diverse maladies, encompassing malignancies and inflammatory afflictions. Molecular formula: C9H14O6. Mole weight: 218.20. | |
| Propargyl b-D-galactopyranoside | Propargyl b-D-galactopyranoside is a pharmacological compound used to explore glycosylation mechanisms. Its adeptness as a sugar substrate analog aids in studying glycosylation reactions implicated in the pathogenesis of cancer, autoimmune disorders, as well as infectious diseases. Molecular formula: C9H14O6. Mole weight: 218.20. | |
| Propionyl 3,4,6-tri-O-acetyl-2-acetamido-2-deoxy-b-D-thiogalactopyranoside | Propionyl 3,4,6-tri-O-acetyl-2-acetamido-2-deoxy-b-D-thiogalactopyranoside is a biomedical compound, used in unraveling intricate carbohydrate-protein interactions, especially within the realm of glycobiology and enzymatic procedures. Molecular formula: C17H25NO10S. Mole weight: 435.45. | |
| Propionyl 3,4,6-Tri-O-acetyl-2-acetamido-2-deoxy-β-D-thiogalactopyranoside | Propionyl 3,4,6-Tri-O-acetyl-2-acetamido-2-deoxy-β-D-thiogalactopyranoside is a key intermediate used in the synthesis of carbohydrate-based drugs. It is an important building block for the development of glycoconjugate vaccines which can be used to treat bacterial infections such as meningitis. Additionally, it is used in the synthesis of glycans for the study of glycoprotein interactions in drug discovery research. Synonyms: 3-[[3,4,6-Tri-O-acetyl-2-(acetylamino)-2-deoxy-α-D-galactopyranosyl]thio]propanoic Acid. CAS No. 936026-72-1. Molecular formula: C17H25NO10S. Mole weight: 435.45. | |
| Propofol 2,3,4-tri-O-benzoyl-b-D-glucuronide methyl ester | Propofol 2,3,4-tri-O-benzoyl-b-D-glucuronide methyl ester is an intriguing derivative, showcasing a remarkable proclivity in the domains of anesthesia, pain alleviation and crucial medical care. Molecular formula: C40H40O10. Mole weight: 680.74. | |
| Propofol-4-Hydroxy-1-D-glucuronide | Propofol-4-Hydroxy-1-D-glucuronide is a metabolite of Propofol, a commonly used sedative. As an important biomarker, it serves as an indicator for assessing the clearance and metabolism of Propofoly. Molecular formula: C18H26O8. Mole weight: 370.39. | |
| Propofol-4-Hydroxy-4-D-glucuronide | Propofol-4-Hydroxy-4-D-glucuronide is a byproduct of Propofol that is an anesthetic and sedative drug, primarily generated in the liver through glucuronidation. Molecular formula: C18H26O8. Mole weight: 370.39. | |
| Propofol b-D-glucuronide sodium salt | Propofol b-D-glucuronide sodium salt is an intravenous biomedical solution, finding application in the research of diverse central nervous system-related conditions, including epilepsy and sedation. Molecular formula: C18H25NaO7. Mole weight: 376.38. | |
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