BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Propofol β-D-Glucuronide | A metabolite of Propofol.Propofol is a short-acting medication that results in a decreased level of consciousness and lack of memory for events. Its uses include the starting and maintenance of general anesthesia, sedation for mechanically ventilated adults, and procedural sedation. Synonyms: 2,6-Bis(1-methylethyl)phenyl β-D-Glucopyranosiduronic Acid; Propofol Glucuronide. Grades: > 95%. CAS No. 114991-26-3. Molecular formula: C18H26O7. Mole weight: 354.39. |  |
| Propofol-D-glucuronide methyl ester | Propofol-D-glucuronide methyl ester is an intriguing compound functioning as both a prodrug and metabolite derived from propofol. Molecular formula: C19H28O7. Mole weight: 368.42. | |
| Propranolol-2-O-b-D-glucuronide | Propranolol-2-O-b-D-glucuronide, a metabolite of the beta-adrenergic blocker propranolol utilized to manage hypertension and cardiac arrhythmias, plays a crucial role in the drug's pharmacokinetics - potentially influencing its efficacy. CAS No. 66322-66-5. Molecular formula: C22H29NO8. Mole weight: 435.47. | |
| Propyl 2-acetamido-2-deoxy-b-D-glucopyranoside | Propyl 2-acetamido-2-deoxy-b-D-glucopyranoside is a paramount compound extensively employed in the biomedical sector serving as a catalyst for drug development and research, focusing on ailments of multiple afflictions, encompassing bacterial infections, inflammation and autoimmune disorders. Synonyms: Propyl 2-acetamido-2-deoxy-b-D-glucopyranoside; N-[(2R,3R,4R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-propoxyoxan-3-yl]acetamide; Propyl N-Acetyl-?-D-glucosamine;Propyl 2-acetamido-2-deoxy- beta -D-glucopyranoside. CAS No. 70832-36-9. Molecular formula: C11H21NO6. Mole weight: 263.3. | |
| Propyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranoside | Propyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranoside is a fascinating compound widely recognized in the biomedical field, serving as an indispensable tool for studying intricate bacterial infections. Synonyms: PROPYL 2-ACETAMIDO-3,4,6-TRI-O-ACETYL-2-DEOXY-BETA-D-GLUCOPYRANOSIDE; [(2R,3S,4R,5R,6R)-5-acetamido-3,4-diacetyloxy-6-propoxyoxan-2-yl]methyl acetate. CAS No. 98346-06-6. Molecular formula: C17H27NO9. Mole weight: 389.4. | |
| Propylbeta-D-glucopyranoside | Propylbeta-D-glucopyranoside is a biomedical product commonly used as a surfactant, emulsifier and component in cell culture media. It is primarily employed in the research and development of drugs targeting metabolic disorders, diabetes and related diseases. Synonyms: Propyl ss-D-glucopyranoside; N-Propyl-beta-D-glucopyranoside; (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-propoxyoxane-3,4,5-triol. Grades: 95%. CAS No. 34384-77-5. Molecular formula: C9H18O6. Mole weight: 222.24. | |
| Propylthiouracil N-b-D-glucuronide | Propylthiouracil N-b-D-glucuronide, an essential pharmaceutical compound, revolutionizes the treatment of hyperthyroidism. With its remarkable ability to inhibit enzymes, this compound exerts its therapeutic effects by meticulously obstructing the production of thyroid hormones. By expertly interfering with the conversion process of T4 to T3, it offers respite from the distressing symptoms associated with hyperthyroidism. Among these symptoms are accelerated heart rate, unwanted weight loss, and excessive perspiration. Synonyms: 1-Deoxy-1-(3,4-dihydro-4-oxo-6-propyl-2-thioxo-1(2H)-pyrimidinyl)- b-D-glucopyranuronic acid. CAS No. 33987-24-5. Molecular formula: C13H18N2O7S. Mole weight: 346.36. | |
| Proscillaridin A | Proscillaridin A is a potent cardiovascular drug used in the research of congestive heart failure and arrhythmias. Proscillaridin A acts by inhibiting the Na+/K+ ATPase pump, which enhances intracellular calcium levels, leading to increased contractility. Synonyms: Scillarenin 3b-rhamnoside; 3-(6-Deoxy-a-L-mannopyranosyloxyl)-14-hydroxybufa-4,20,22-trienolide. CAS No. 466-06-8. Molecular formula: C30H42O8. Mole weight: 530.65. | |
| Prostaglandin E2 | Prostaglandin E2 is a naturally occurring COX product used as a medication in labor induction, bleeding after delivery, and termination of pregnancy. It directly targets muscle stem cells (MuSCs) via EP4 receptor, resulting in MuSC expansion. Uses: Endogenous prostaglandin and primary product of arachidonic acid/cyclooxygenase pathway. Synonyms: Dinoprostone; PGE2; Prostin E2; Prepidil. Grades: >98%. CAS No. 363-24-6. Molecular formula: C20H32O5. Mole weight: 352.47. | |
| proTAME | proTAME is a cell-permeable prodrug of N-4-tosyl-L-arginine methyl ester (TAME), which is an inhibitor of the anaphase-promoting complex/cyclosome (APC/C) suppressing its activation by Cdc20 and Cdh1. It induces mitotic arrest by activating the spindle assembly checkpoint (SAC). Synonyms: Pro-N-4-tosyl-L-arginine methyl ester; Methyl (2S) -5- [bis [ (2-phenylacetyl) oxymethoxycarbonylamino] methylideneamino] -2- [ (4-methylphenyl) sulfonylamino] pentanoate. Grades: ≥90%. CAS No. 1362911-19-0. Molecular formula: C34H38N4O12S. Mole weight: 726.75. | |
| PRP-194 | PRP-194 is a pyrrolopyridine derivative with molecule weight 194.66. Currently there is no formal name with this intermediate, and we temporally call this product as PRP-194. PRP-194 is an important intermediate for the synthesis of fluorescent dyes. Synonyms: PRP 194; PRP194; 5-chloro-2,3,3-trimethyl-3H-pyrrolo[2,3-b]pyridine. CAS No. 596085-87-9. Molecular formula: C10H11ClN2. Mole weight: 194.66. | |
| PRT4165 | PRT4165 is a small molecule inhibitor of polycomb repressive complex 1, which inhibits ubiquitin signaling at DNA double-strand breaks. PRT4165 is a potent inhibitor of PRC1-mediated H2A ubiquitylation in vivo and in vitro. Synonyms: PRT4165; PRT-4165; PRT 4165. Grades: 98%. CAS No. 31083-55-3. Molecular formula: C15H9NO2. Mole weight: 235.24. | |
| PS 48 | PS 48 is an allosteric activator of phosphoinositide-dependent protein kinase 1 (PDPK1; PDK1) binding to the PIF-binding pocket of PDK1. Synonyms: PS-48; PS 48; PS48; (Z)-5-(4-Chlorophenyl)-3-phenylpent-2-enoic acid; (2z)-5-(4-Chlorophenyl)-3-Phenylpent-2-Enoic Acid. Grades: 99%. CAS No. 1180676-32-7. Molecular formula: C17H15ClO2. Mole weight: 286.75. | |
| PSB 0788 | PSB 0788 is a selective A2B antagonist. Synonyms: PSB-0788; PSB 0788; PSB0788. 8-[4-[4-(4-Chlorobenzyl)piperazide-1-sulfonyl)phenyl]]-1-propylxanthine. CAS No. 1027513-54-7. Molecular formula: C25H27ClN6O4S. Mole weight: 543.04. | |
| PSB 1115 | PSB 1115 is a selective human A2B receptor antagonist. Synonyms: PSB1115; PSB-1115; Benzenesulfonic acid, 4-(2,3,6,9-tetrahydro-2,6-dioxo-1-propyl-1H-purin-8-yl)-; 4-(2,3,6,9-Tetrahydro-2,6-dioxo-1-propyl-1H-purin-8-yl)benzenesulfonic acid; Benzenesulfonic acid, 4-(2,3,6,7-tetrahydro-2,6-dioxo-1-propyl-1H-purin-8-yl)-. Grades: ≥95%. CAS No. 152529-79-8. Molecular formula: C14H14N4O5S. Mole weight: 350.35. | |
| PSB 12379 | PSB 12379, an α,β-Methylene-ADP (AOPCP) derivative, is a potent Ecto-5'-Nucleotidase (CD73) inhibitor with Kis of 9.03 nM (rat) and 2.21 nM (human). PSB-12379 displayed high selectivity versus other ecto-nucleotidases (NTPDase 1-3 and NPP 1-3) and ADP-activated P2Y (P2Y1 and P2Y12) receptors. PBS-12379 represents the most potent eN inhibitor known to date, showing high selectivity and metabolic stability. Synonyms: PSB12379; PSB-12379; N6-Benzyl-α,β-methyleneadenosine 5'-diphosphate; N6-benzyl-(alpha,beta)-methylene-ADP; (1-Deoxy-1-(6-benzylamino-9H-purine-9-yl)-beta-D-ribofuranose-5-O-yl)phosphonylmethylphosphonic acid; N-Benzyl-5'-O-[hydroxy (phosphonomethyl) phosphoryl]adenosine; N-(phenylmethyl)-adenosine, 5'-[hydrogen P-(phosphonomethyl)phosphonate]. Grades: ≥98% by HPLC. CAS No. 1802226-78-3. Molecular formula: C18H23N5O9P2. Mole weight: 515.35. | |
| PSB 603 | PSB 603 is a highly selective A2B antagonis. Synonyms: PSB603; PSB 603; PSB-603. 8-[4-[4-(4-Chlorophenzyl)piperazide-1-sulfonyl)phenyl]]-1-propylxanthine. CAS No. 1092351-10-4. Molecular formula: C24H25ClN6O4S. Mole weight: 529.01. | |
| Pseudaminic acid | Pseudaminic acid is an indispensable compound in the biomedical sector assuming a pivotal involvement in the synthesis of pseudaminic acid capsules, designated for studying bacterial infections resulting from pathogens that express pseudaminic acid-binding proteins. Synonyms: 5,7-Bis(acetylamino)-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-2-nonulopyranosonic acid. Molecular formula: C13H22N2O8. Mole weight: 334.32. | |
| Psicose diacetonide | Psicose diacetonide is a chemical compound revered in the realms of the biomedical industry for its profound capabilities in studying a myriad of diseases, including the ominous cancer. Synonyms: 2,3:4,5-Di-O-isopropylidene-a-D-psicopyranose. CAS No. 205582-81-6. | |
| PTC299 | PTC299, a VEGF inhibitor, is an orally bioavailable, small molecule inhibitor of vascular endothelial growth factor (VEGF) synthesis with potential antiangiogenesis and antineoplastic activities. VEGF inhibitor PTC299 targets post-transcriptionally by selectively binding the 5'- and 3'-untranslated regions (UTR) of VEGF messenger RNA (mRNA), thereby preventing translation of VEGF. This inhibits VEGF protein production and decreases its levels in the tumor and bloodstream. In turn, this may result in the inhibition of migration, proliferation and survival of endothelial cells, microvessel formation, the inhibition of tumor cell proliferation, and eventually the induction of tumor cell death. VEGFs are upregulated in a variety of tumor cell types and play key roles during angiogenesis. In addition, PTC299 may enhance the antitumor activity of other chemotherapeutic agents. PTC299, is currently in Phase II trials as a potential agent to treat vestibular schwannoma. Synonyms: Emvododstat; 4-Chlorophenyl (1S)-6-Chloro-1,3,4,9-tetrahydro-1-(4-methoxyphenyl)-2H-pyrido[3,4-b]indole-2-carboxylate; 2H-Pyrido(3,4-b)indole-2-carboxylic acid, 6-chloro-1,3,4,9-tetrahydro-1-(4-methoxyphenyl)-, 4-chlorophenyl ester, (1S)-; 6-chloro-1,3,4,9-tetrahydro-1-(4-methoxyphenyl)-, 4-chlorophenyl ester, (1S)-2H-pyrido(3,4-b)indole-2-carboxylic acid. Grades: ≥98%. CAS No. 1256565-36-2. Molecular formula: C25H20Cl2N2O3. Mole weight: 467.34. | |
| p-Topolin-9-glucoside | p-Topolin-9-glucosid, derived from plants, is an organic element that displays considerable potential due to its cytokinin properties, which effectively stimulate cell division and growth. Synonyms: 6-(4-hydroxybenzylamino)-9-b-D-glucopyranosylpurine. CAS No. 1046433-04-8. Molecular formula: C18H21N5O6. Mole weight: 403.39. | |
| Ptp1B-In-2 | Ptp1B-In-2 is a selective protein tyrosine phosphatase-1B (PTP1B) inhibitor. Synonyms: Ptp1B In 2; MDK3465; MDK-3465; MDK 3465; methyl 5-(N-(4-(N-(2-methoxy-2-oxoethyl)methylsulfonamido)benzyl)-1-phenylmethylsulfonamido)-2-((4-methylbenzyl)oxy)benzoate. CAS No. 1919853-46-5. Molecular formula: C34H36N2O9S2. Mole weight: 680.79. | |
| PTZ-256 | PTZ-256 is a phenothiazine derivative with chemical name: 3-(10H-phenothiazin-10-yl)propane-1-amine. PTZ-256 has molecule weight 256, therefore, we call it as PTZ-256. Synonyms: PTZ 256; PTZ256; 3-(10H-phenothiazin-10-yl)propan-1-amine; N-(3-aminopropyl)phenothiazine; 10-(3-aminopropyl)phenothiazine. CAS No. 2095-21-8. Molecular formula: C15H16N2S. Mole weight: 256.37. | |
| Purpurogallin | Purpurogallin is a red, crystalline compound, and the aglycon of several glycosides from nutgalls and oak barks. It can inhibit hydroxyestradiol methylation by catechol-O-methyltransferase. It potently and specifically inhibits PLK, TLR1/TLR2 activation pathway. Purpurogallin showed antiplatelet and antithrombotic activities; anti - inflammatory effects; antitumor activity, anti-oxidation activities; hepatoprotecting effects; antibacterial activity toward gram-positive bacteria. Synonyms: 2,3,4,6-Tetrahydroxy-5H-benzocyclohepten-5-one; NSC 35676; BRN 1978265. Grades: 98%. CAS No. 569-77-7. Molecular formula: C11H8O5. Mole weight: 220.18. | |
| PV-10 | PV-10 is an injectable ten percent solution of rose bengal disodium, an iodinated fluorescein derivative, with potential antineoplastic and radiosensitizing activities. When injected into tumor tissue, PV-10 specifically targets and concentrates in tumor cells, producing cytotoxic singlet oxygen when exposed to ionizing radiation. In addition, PV-10 may stimulate an anti-tumor immune response. Synonyms: Rose bengal sodium; PV 10; PV10; Bengal Rose B sodium salt; 4,5,6,7-Tetrachloro-2',4',5',7'-tetraiodofluorescein disodium salt. CAS No. 11121-48-5. Molecular formula: C20H2Cl4I4Na2O5. Mole weight: 1017.64. | |
| PX-316 | PX-316 is a AKT inhibior. PX-316, when administered intraperitoneally to mice at 150 mg/kg, inhibits Akt activation in HT-29 human tumor xenografts up to 78% at 10 h with recovery to 34% at 48 h. PX-316 has antitumor activity against early human MCF-7 breast cancer and HT-29 colon cancer xenografts in mice. PX-316 formulated in 20% hydroxypropyl-beta-cyclodextrin for intravenous administration is well tolerated in mice and rats with no hemolysis and no hematological toxicity. Thus, PX-316 is the lead compound of a new class of potential agents that inhibit Akt survival signaling. Synonyms: PX 316; PX316; D-3-Deoxyphosphatidylinositol Ether Lipid; NSC710297; NSC-710297; Phosphoric acid,2R,3S,4R,6R)-2,3,4,6-tetrahydroxycyclohexyl ester; 1-O-(1-O-Octadecyl-2-O-methyl-L-glycero-3-phospho)-3-deoxy-D-myo-inositol. CAS No. 253440-95-8. Molecular formula: C28H57O10P. Mole weight: 584.73. | |
| PYR-41 | PYR-41 is a ubiquitin-activating enzyme inhibitor (UBE1 inhibitor). PYR-41 blocks ubiquitination reactions but paradoxically leads to the accumulation of high MW ubiquitinated proteins. PYR-41 also mediated cross-linking of specific protein kinases (Bcr-Abl, Jak2) to inhibit their signaling activity. PYR-41 has demonstrated anti-tumor activity in animal studies, partially selective protein cross-linking may represent an alternate approach to affect signal transduction modules and ubiquitin cycle-regulatory proteins for cancer therapy. Synonyms: PYR-41; PYR 41; PYR41. Grades: 0.98. CAS No. 418805-02-4. Molecular formula: C17H13N3O7. Mole weight: 371.305. | |
| PYR4897 | PYR4897 is a useful intermediate for chemical synthesis. It is used for synthetizing a number of biologically important molecules, such as porphyrins, photosensitizers, bile pigments and anticancer drugs and so on. Uses: Pyr4897 is used for synthetizing a number of biologically important molecules, such as porphyrins, photosensitizers, bile pigments and anticancer drugs and so on. Synonyms: Tert-butyl 4-(2-methoxycarbonylethyl)-3,5-dimethyl-1H-pyrrole-2-carboxylate; PYR-4897; PYR 4897. Grades: 98%. CAS No. 60024-89-7. Molecular formula: C15H23NO4. Mole weight: 281.35. | |
| PYR5084 | PYR5084 is a useful intermediate for chemical synthesis. It is used for synthetizing a number of biologically important molecules, such as porphyrins, photosensitizers, bile pigments and anticancer drugs and so on. Uses: Pyr5084 is used for synthetizing a number of biologically important molecules, such as porphyrins, photosensitizers, bile pigments and anticancer drugs and so on. Synonyms: 3,4-Dimethyl-5-formyl-1H-pyrrole-2-carboxylic acid benzyl ester; 1H-Pyrrole-2-carboxylic acid, 5-formyl-3,4-dimethyl-, phenylmethyl ester. Grades: 98%. CAS No. 59435-08-4. Molecular formula: C15H15NO3. Mole weight: 257.29. | |
| PYR5120 | PYR5120 is a useful intermediate for chemical synthesis. It is used for synthetizing a number of biologically important molecules, such as porphyrins, photosensitizers, bile pigments and anticancer drugs and so on. Uses: Pyr5120 is used for synthetizing a number of biologically important molecules, such as porphyrins, photosensitizers, bile pigments and anticancer drugs and so on. Synonyms: PYR-5120; PYR 5120; 1H-Pyrrole-2-carboxylic acid, 5-formyl-3,4-dimethyl-, 1,1-dimethylethylester. Grades: 98%. CAS No. 59435-12-0. Molecular formula: C12H17NO3. Mole weight: 223.27. | |
| PYR8535 | PYR8535 is pyrrole derivative. It is used as a useful intermediate for chemical synthesis of a number of biologically important molecules, including bile pigments, porphyrins, photosensitizers and anticancer drugs and so on. Uses: Pyr8535 is used as a useful intermediate for chemical synthesis of a number of biologically important molecules, including bile pigments, porphyrins, photosensitizers and anticancer drugs and so on. Synonyms: PYR 8535; PYR-8535; 1H-Pyrrole-3-propanoic acid, 5-formyl-4-methyl-2-[(phenylmethoxy)carbonyl]-, methyl ester. Grades: 98%. CAS No. 62618-53-5. Molecular formula: C18H19NO5. Mole weight: 329.35. | |
| Pyridone 6 | Pyridone 6 is a potent and selective inhibitor of JAK1, JAK2, JAK3, and Tyk2, displaying significantly weaker affinities for other protein tyrosine kinases. It was shown to block IL-2 and IL-4-dependent proliferation of mouse T-cell lymphoma cells. Synonyms: Pyridone 6; Pyridone-6; Pyridone6; CMP 6; JAK Inhibitor I; Janus-Associated Kinase Inhibitor I. Grades: >98%. CAS No. 457081-03-7. Molecular formula: C18H16FN3O. Mole weight: 309.34. | |
| Pyridostatin TFA salt | Pyridostatin stabilizes G-quadruplexes (G4s) in cells and elicits a DNA damage response by causing the formation of DNA double strand breaks (DSB). Synonyms: 4-(2-aminoethoxy)-N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)pyridine-2,6-dicarboxamide tris(2,2,2-trifluoroacetate); Pyridostatin; PDS; Pyridostatin TFA salt. Grades: 98%. CAS No. 1472611-44-1. Molecular formula: C37H35F9N8O11. Mole weight: 938.72. | |
| Pyridoxal galactoside | Pyridoxal galactoside is a biomedical compound, exhibiting promising in studying specific disorders associated with vitamin B6 deficiency or metabolism. By serving as a precursor to pyridoxal is an active variant of vitamin B6, it facilitates various enzymatic reactions involved in neurotransmitter synthesis. Molecular formula: C14H19O8N. Mole weight: 329.31. | |
| Pyridoxine galactoside | Pyridoxine galactoside is an essential biomolecular compound, used in studying vitamin B6 deficits. Serving as a pivotal antecedent to the dynamic configuration of pyridoxine's active state, this compound exerts an indispensable role in disparate enzymatic reactions and the intricate process of neurotransmitter synthesis. Molecular formula: C14H21NO8. Mole weight: 331.3. | |
| Pyrogallol a-D-glucopyranoside | Pyrogallol a-D-glucopyranoside is a paramount bioactive compound with profound antioxidant capabilities, aiding in research of a plethora of afflictions, notably diabetes, cancer and cardiovascular maladies. Molecular formula: C12H16O8. Mole weight: 288.25. | |
| Pyroxamide | Pyroxamide is a synthetic derivative of hydroxamic acid with antineoplastic properties, Pyroxamide inhibits histone deacetylases involved in transcription; induces hyperacetylation of core histones, modulating chromatin structure and affecting transcription of some genes that inhibit tumor growth; and induces growth arrest and apoptosis. Pyroxamide is used in clinical studies for cancer chemotherapy. Synonyms: N1-hydroxy-N8-(pyridin-3-yl)octanediamide; N-Hydroxy-N'-3-pyridinyloctanediamide; Octanedioic acid hydroxyamide pyridin-3-ylamide. Grades: 99%. CAS No. 382180-17-8. Molecular formula: C13H19N3O3. Mole weight: 265.313. | |
| PYZD-4409 | PYZD-4409 is an inhibitor of ubiquitin-activating enzyme UBA1 (E1). PYZD-4409 induced cell death in malignant cells and preferentially inhibited the clonogenic growth of primary acute myeloid leukemia cells compared with normal hematopoietic cells. Mechanistically, genetic or chemical inhibition of E1 increased expression of E1 stress markers. Moreover, BI-1 overexpression blocked cell death after E1 inhibition, suggesting ER stress is functionally important for cell death after E1 inhibition. Finally, in a mouse model of leukemia, intraperitoneal administration of PYZD-4409 decreased tumor weight and volume compared with control without untoward toxicity. Thus, our work highlights the E1 enzyme as a novel target for the treatment of hematologic malignancies. Synonyms: PYZD-4409; PYZD 4409; PYZD4409. Grades: 0.98. CAS No. 423148-78-1. Molecular formula: C14H7ClFN3O5. Mole weight: 351.674. | |
| QC | | |
| QC-3611 | QC-3611 is a selective inhibitor of JARID1A/1B, which is a target existing in various tumors (JARID1A IC50 = 13 nM ;JARID1B IC50 = 2 nM). QC-3611 is promisingly to be used as an antineoplastic drug. Uses: Potential antineoplastic drug. Synonyms: QC 3611; QC3611. CAS No. 1613410-75-5. Molecular formula: C17H14ClN3O3. Mole weight: 343.76. | |
| QS11 | QS11 contains a planar purine ring with C2, C6, and N9-positions substituted. QS11, a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor, ) was demonstrated to synergize with Wnt proteins to activate b-catenin signaling. Synonyms: (2S)-2-[[2-(2,3-dihydro-1H-inden-5-yloxy)-9-[(4-phenylphenyl)methyl]purin-6-yl]amino]-3-phenylpropan-1-ol; QS 11; QS-11; QS 11 (QS11,BML-WN117); (2S)-2-{[9-(4-Biphenylylmethyl)-2-(2,3-dihydro-1H-inden-5-yloxy)-9H-purin-6-yl]amino}-3-phenyl-1-propanol; J-501013. Grades: >98%. CAS No. 944328-88-5. Molecular formula: C36H33N5O2. Mole weight: 567.68. | |
| Quercetin 3-b-D-galactoside | Quercetin 3-b-D-galactoside is a naturally occurring compound widely distributed in plant sources like apples and onions, showcasing remarkable characteristics as a potent antioxidant and anti-inflammatory compound. This biomedical industry treasure serves for studying cardiovascular ailments, allergies and even as a growth suppressor for malignant cells. Synonyms: Hyperoside; 2-(3,4-Dihydroxyphenyl)-3-(b-D-galactopyranosyloxy)-5,7-dihydroxy-4H-1-benzopyran-4-one; Hyperin. Molecular formula: C21H20O12. Mole weight: 464.38. | |
| Quercetin 3-b-D-glucopyranoside | Quercetin 3-b-D-glucopyranoside is a naturally occurring flavonoid compound abundantly present in diverse botanical sources, a widely acknowledged dietary supplement extensively employed in the biomedical field. Renowned for its exceptional prowess as an antioxidant and anti-inflammatory compound, this product exhibits remarkable efficacy in counteracting the perils of oxidative stress and ailments linked to inflammation. Remarkably, the immense therapeutic potential of Quercetin 3-b-D-glucopyranoside extends to the research of chronic maladies encompassing cancer, cardiovascular afflictions and neurodegenerative disorders. Synonyms: Isoquercitrin; Quercetin 3-b-D-glucoside. Molecular formula: C21H20O12. Mole weight: 464.38. | |
| Quercetin-3-O-b-D-glucose-7-O-b-D-gentiobiosiden | Cas No. 60778-02-1. | |
| Quercetin 4'-Glucoside | Cas No. 20229-56-5. | |
| Quercetin 7-O-b-D-glucuronide | Quercetin 7-O-b-D-glucuronide is a well-known compound, holding immense application in the realm of disease research. Acting as a potent antioxidant, it showcases remarkable anti-inflammatory properties, thereby facilitating the research for an array of afflictions including cancer, cardiovascular disorders and neurodegenerative diseases. Synonyms: Quercetin 7-glucuronide; 38934-20-2; (2S,3S,4S,5R,6S)-6-((2-(3,4-Dihydroxyphenyl)-3,5-dihydroxy-4-oxo-4H-chromen-7-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid; (2S,3S,4S,5R,6S)-6-[2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-4-oxochromen-7-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid; Quercetin 7-O-|A-D-Glucuronide; DTXSID90469884; HY-W778608; QUERCETIN 7-O-BETA-D-GLUCURONIDE; CS-0855348; (2S,3S,4S,5R,6S)-6-{[2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-4-oxo-4H-chromen-7-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid. CAS No. 38934-20-2. Molecular formula: C21H18O13. Mole weight: 478.36. | |
| Quercetin-7-O-β-D-glucopyranoside | Cas No. 491-50-9. | |
| quinethazone | Quinethazone is a thiazide-like diuretic. It is a carbonic anhydrase inhibitor and can be used for the treatment of hypertension. Uses: Hypertension. Synonyms: 2-Ethyl-7-chloro-1,2,3,4-tetrahydro-4-oxoquinazoline-6-sulfonamide; 2-Ethyl-7-chloro-2,3-dihydro-4(1H)-quinazolone-6-sulfonamide; Aquamox; CL 36010; Hydromox; Idrokin; Quimethazin; Quinethazon; Quinethazonum; 7-Chloro-2-ethyl-1,2,3,4-tetrahydro-4-oxo-6-quinazolinesulfonamide; 7-Chloro-2-ethyl-1,2,3,4-tetrahydro-4-oxo-6-sulfamoylquinazoline; 7-Chloro-2-ethyl-6-sulfamyl-1,2,3,4-tetrahydro-4-quinazolinone. Grades: 98%. CAS No. 73-49-4. Molecular formula: C10H12ClN3O3S. Mole weight: 289.74. | |
| QX77 | QX-77 is an activator of molecular chaperone-mediated autophagy (CMA). It can induce the up-regulation of Rab11 expression and up-regulate the expression of LAMP2A. Grades: 98%. CAS No. 1798331-92-6. Molecular formula: C16H13ClN2O2. Mole weight: 300.74. | |
| R-130823 | R-130823 is a highly selective inhibitor against mitogen-activated protein kinase p38alpha (IC50=22 nM). The release of tumor necrosis factor-alpha, interleukin-1beta, -6 and -8 was inhibited in lipopolysaccharide-stimulated human blood pretreated by R-130823, with IC50 values of 0.089, 0.066, 0.95 and 0.16 microM, respectively. Synonyms: R130823; R 130823; 2-(4-Fluorophenyl)-4-(1-phenethyl-1,2,3,6-tetrahydropyridin-4-yl)-3-(pyridin-4-yl)-1H-pyrrole. CAS No. 321344-32-5. Molecular formula: C28H26FN3. Mole weight: 423.53. | |
| R1487 HCl | R1487 is an orally bioavailable and highly selective inhibitor of p38α mitogen-activated protein kinase, with Kd values of 0.2 nM and 29 nM for p38α and p38β, respectively. Synonyms: R1487 ; R 1487 ; R-1487 ; R1487 HCl. Grades: 98%. CAS No. 449808-64-4. Molecular formula: C19H19ClF2N4O3. Mole weight: 424.83. | |
| R306465 | R306465, also known as JNJ-16241199, is a novel hydroxamate-based histone deacetylase (HDAC) inhibitor with broad-spectrum antitumour activity against solid and haematological malignancies in preclinical models. R306465 was found to be a potent inhibitor of HDAC1 and -8 (class I) in vitro. R306465 potently inhibited cell proliferation of all main solid tumour indications, including ovarian, lung, colon, breast and prostate cancer cell lines, with IC50 values ranging from 30 to 300 nM. The high activity of R306465 in cell-based assays and in vivo after oral administration makes R306465 a promising novel antitumoral agent with potential applicability in a broad spectrum of human malignancies. Uses: Histone deacetylase inhibitors. Synonyms: R 306465; R-306465; JNJ-16241199; JNJ16241199; JNJ 16241199. CAS No. 604769-01-9. Molecular formula: C19H19N5O4S. Mole weight: 413.45. | |
| R763 | Cas No. 871357-89-0. | |
| rac-Ketoprofen acyl-beta-D-glucuronide (mixture of isomers) | A metabolite of Ketoprofen. Synonyms: 1-(3-Benzoly-a-methylbenzeneacetate)-b-D-glucopyranuronic acid; Ketoprofen Glucuronide. Grades: > 95%. CAS No. 76690-94-3. Molecular formula: C22H22O9. Mole weight: 430.40. | |
| rac-Lotaustralin | rac-Lotaustralin is a prodigious and potent compound used for studying the menacing forces of breast and lung carcinomas. Synonyms: 2-(b-D-Glucopyranosyloxy)-2-methylbutyronitrile. Molecular formula: C11H19NO6. Mole weight: 261.27. | |
| (Rac)-SEP-363856 hydrochloride | (Rac)-SEP-363856 is the racemate of SEP-363856, a trace amine-associated receptor 1 (TAAR1) agonist used in the research of schizophrenia. Synonyms: (Rac)-SEP-363856 HCl; (Rac)-SEP-856 HCl; (Rac)-SEP-856 hydrochloride. CAS No. 1310422-02-6. Molecular formula: C9H13NOS.HCl. Mole weight: 219.73. | |
| RAD1901 HCl salt | Cas No. 1349723-93-8. | |
| Radicamine A | Radicamine A, a product of Rabdosia japonica, possesses impressive potential as an anticancer agent. Promising results indicate selectivity in its cytotoxic action against cancer cells, warranting its further development as a potential treatment for gastric and colon cancer. Extending the horizons for cancer therapeutics, Radicamine A presents an intriguing opportunity for cutting-edge drug development. Synonyms: (2R)-3beta,4alpha-Dihydroxy-5beta-(3-hydroxy-4-methoxyphenyl)pyrrolidine-2alpha-methanol; 3,4-Pyrrolidinediol, 2-(3-hydroxy-4-methoxyphenyl)-5-(hydroxymethyl)-, (2R,3R,4R,5R)-; (2R,3R,4R,5R)-2-(3-Hydroxy-4-methoxyphenyl)-5-(hydroxymethyl)-3,4-pyrrolidinediol. Grades: 95%. CAS No. 431981-74-7. Molecular formula: C12H17NO5. Mole weight: 255.27. | |
| Radicamine B | Radicamine B, a formidable antitumor antibiotic, exerts its actions as a DNA intercalator and DNA polymerase inhibitor, thereby inducing cancer cell apoptosis. Remarkably efficacious in combating diverse cancer forms, such as breast, lung, and colon cancer, this compound stands as a hopeful beacon in the fight against neoplastic disorders. Its remarkable potential warrants further exploration and experimentation. Synonyms: 3,4-Pyrrolidinediol, 2-(hydroxymethyl)-5-(4-hydroxyphenyl)-, (2R,3R,4R,5R)-; (2R,3R,4R,5R)-2-(Hydroxymethyl)-5-(4-hydroxyphenyl)-3,4-pyrrolidinediol. Grades: 95%. CAS No. 431981-75-8. Molecular formula: C11H15NO4. Mole weight: 225.24. | |
| Raloxifene 4-D-glucuronide D4 | Raloxifene 4-D-glucuronide D4 is a formidable metabolite derived from Raloxifene, renowned for its usage in studying osteoporosis within postmenopausal women. Molecular formula: C34H31NO10SD4. Mole weight: 653.73. | |
| Raloxifene-4-D-glucuronide D4 lithium salt | Raloxifene-4-D-glucuronide D4 lithium salt is a notable biomedical compound, aiding in studying postmenopausal osteoporosand breast cancer. Operating as a discerning estrogen receptor modulator, this stable derivative of Raloxifene showcases enhanced solubility and bioavailability conferred by its salt form. Molecular formula: C34H30NO10SD4 Li. Mole weight: 659.66. | |
| Raloxifene-4-D-glucuronide lithium salt | Raloxifene-4-D-glucuronide lithium salt is an esteemed biomedical compound, ingeniously deployed for studying the ravages of osteoporosand curbing the sinister growth of breast cancer. This prodigious innovation is a cleverly modified iteration of raloxifene, an acclaimed selective estrogen receptor modulator (SERM). Molecular formula: C34H34NO10S Li. Mole weight: 655.64. | |
| Raloxifene 6-D-glucuronide | Raloxifene 6-D-glucuronide is a formidable and discriminative estrogen receptor modulator (SERM), aiding in unraveling the intricate labyrinth of Raloxifene's metabolic pathways and elimination mechanisms. Synonyms: 2- (4-Hydroxyphenyl) -3-[4-2[2- (1-piperindinyl) ethoxybenzoyl]benzo[b]thien-6-yl]-b-D-glucopyranosiduronic acid. Molecular formula: C34H35NO10S. Mole weight: 649.71. | |
| Raloxifene 6-D-glucuronide D4 | Raloxifene 6-D-glucuronide D4 is a pharmacological compound for studying osteoporosand breast carcinoma acting as an estrogen receptor modifier. Molecular formula: C34H31NO10SD4. Mole weight: 653.73. | |
| Raloxifene-6-D-glucuronide D4 lithium salt | Raloxifene-6-D-glucuronide D4 lithium salt is a vital pharmaceutical compound extensively employed in the biomedical sector with application revolving around the research of osteoporosis in postmenopausal females. This compound functions as an extraordinary selective estrogen receptor modulator. Molecular formula: C34H30NO10SD4 Li. Mole weight: 659.66. | |
| Raloxifene-6-D-glucuronide lithium salt | Raloxifene-6-D-glucuronide lithium salt is a biomedical compound, used for studying the scourge of osteoporosand hormone receptor-positive breast cancer. It is perched as a lithium salt derivative of Raloxifene-6-D-glucuronide. Molecular formula: C34H34NO10S Li. Mole weight: 655.64. | |
| Raltegravir b-D-glucuronide methyl ester | Raltegravir b-D-glucuronide methyl ester is an invaluable pharmaceutical compound extensively applied in the biomedical industry, exhibiting profound application in studying human immunodeficiency virus (HIV) infections. It is renowned for its ability to inhibit HIV integrase enzyme. Synonyms: 4-[[[(4-Fluorophenyl)methyl]amino]carbonyl]-1,6-dihydro-1-methyl-2-[1-methyl-1-[[(5-methyl-1,3,4-oxadiazol-2-yl)carbonyl]amino]ethyl]-6-oxopyrimidin-5-yl-D-Glucopyranosiduronic Acid Methyl Ester. Molecular formula: C27H31FN6O11. Mole weight: 634.57. | |
| Raltegravir β-D-Glucuronide | A metabolite of Raltegravir.Raltegravir is an integrase inhibitor as antiretroviral drug. It can be used for the treatment of HIV infection. Synonyms: 4-[[[(4-Fluorophenyl)methyl]amino]carbonyl]-1,6-dihydro-1-methyl-2-[1-methyl-1-[[(5-methyl-1,3,4-oxadiazol-2-yl)carbonyl]amino]ethyl]-6-oxopyrimidin-5-yl β-D-Glucopyranosiduronic Acid. Grades: > 95%. CAS No. 952654-62-5. Molecular formula: C26H29FN6O11. Mole weight: 620.54. | |
| Ramipril Acyl-β-D-glucuronide | A metabolite of ramipril.Ramipril is an angiotensin-converting enzyme inhibitor. It can be used for treatment of hypertension and congestive heart failure. Synonyms: 1- [ (2S, 3aS, 6aS) -1- [ (2S) -2- [ [ (1S) -1- (Ethoxycarbonyl) -3-phenylpropyl]amino]-1-oxopropyl]octahydrocyclopenta [b]pyrrole-2-carboxylate] β-D-Glucopyranuronic Acid. Grades: > 95%. CAS No. 1357570-21-8. Molecular formula: C29H40N2O11. Mole weight: 592.63. | |
| Ramiprilat acyl-b-D-glucuronide | Ramiprilat acyl-b-D-glucuronide is a biomedical product of significant relevance, holding applications in studying hypertension and congestive heart failure. Its vital role as a metabolite of Ramipril, an antihypertensive compound widely employed for blood pressure reduction. Molecular formula: C27H36N2O11. Mole weight: 564.59. | |
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