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| Product | Description | |
|---|---|---|
| Cefetamet Pivoxil Hydrochloride | The hydrochloride salt form of Cefetamet pivoxil, one of the third generation cephalosporin antibiotics, could be effective in the treatment for sorts of infections caused by sensitive bacteria. Uses: The hydrochloride salt form of cefetamet pivoxil could be effective in the treatment for sorts of infections caused by sensitive bacteria. Synonyms: Cefetamet pivoxil hydrochloride; CS-O-14591. Grades: 95%. CAS No. 111696-23-2. Molecular formula: C20H26ClN5O7S2. Mole weight: 548.03. |  |
| Cefonicid sodium | Cefonicid sodium is a broadspectrum cephalosporin antibiotic which can be detected using adsorptive square-wave stripping voltammetry. Uses: A semisynthetic second-generation broadspectrum cephalosporin with antibacterial activity that inhibits the formation of the bacterial cell wall. Synonyms: disodium;(6S,7S)-7-[[(2S)-2-hydroxy-2-phenylacetyl]amino]-8-oxo-3-[[1-(sulfonatomethyl)tetrazol-5-yl]sulfanylmethyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate. Grades: ≥95%. CAS No. 61270-78-8. Molecular formula: C18H16N6Na2O8S3. Mole weight: 586.53. | |
| Cefoselis hydrochloride | Cefoselis, a new parenteral cephalosporin, is a widely used beta-lactam antibiotic and is active against clinical isolates of both gram-positive and gram-negative aerobic bacteria. It showed potent antibacterial activity against Hemophilus influenzae and Moraxella catarrhalis. It was highly active against MSSA and MSCNS, but it was poor in the activity against MRSA,MRCNS,PRSP and Enterococcus faecalis, and had no activity for Enterococcus faecium. Synonyms: Wincef hydrochloride. Grades: >98%. CAS No. 911212-25-4. Molecular formula: C19H23ClN8O6S2. Mole weight: 559.02. | |
| Cefoselis sulfate | Cefoselis sulfate is a stable cephalosporin for BETA-lactamase. The drug shows antimicrobial activity for a wide range of bacteria including Pseudomonas. Synonyms: Winsef; (6R- (6alpha, 7beta (Z)))-7- ( ( (2-Amino-4-thiazolyl) (methoxyimino)acetyl)amino)-3- ( (2, 3-dihydro-2- (2-hydroxyethyl)-3-imino-1H-pyrazol-1-yl)methyl)-8-oxo-5-Thia-1-azabicyclo (4. 2. 0)oct-2-ene-2-carboxylic acid sulfate. Grades: 0.98. CAS No. 122841-12-7. Molecular formula: C19H22N8O6S2.H2SO4. Mole weight: 620.64. | |
| Cefpiramide sodium | Cefpiramide sodium is a new Pseudomonas-active cephalosporin with a broad spectrum of antibacterial activity. It was more active against Acinetobacter spp. and Pseudomonas spp. It inhibited many Pseudomonas aeruginosa resistant to carbenicillin, piperacillin, and cefotaxime, but it was less active than ceftazidime and cefsulodin. It also inhibited staphylococci and streptococci and had appreciable activity against Streptococcus faecalis and Listeria moncytogenes. Uses: Anti-bacterial agents. Synonyms: SM-1652; Wy-44635; SM 1652; Wy 44635; SM1652; Wy44635. Grades: >98%. CAS No. 74849-93-7. Molecular formula: C25H23N8NaO7S2. Mole weight: 635.63. | |
| Cefprozil monohydrate | Cefprozil hydrate (Cefzil) is a second-generation cephalosporin type antibiotic. Cefprozil hydrate (Cefzil) can be used to treat bronchitis, ear infections, skin infections, and other bacterial infections. Uses: Beta lactam antibiotics. Grades: >98%. CAS No. 121123-17-9. Molecular formula: C18H19N3O5S.H2O. Mole weight: 407.44. | |
| Ceftaroline Fosamil | Ceftaroline fosamil is a cephalosporin antibacterial indicated for the treatment of adults with acute bacterial skin and soft tissue infections, including those caused by methicillin-resistant Staphylococcus aureus (MRSA). Synonyms: PPI 0903; PPI0903; PPI-0903; T-91825; T 91825; T91825; Teflaro; Zinforo; (6R,7R)-7-[[(2Z)-2-ethoxyimino-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetyl]amino]-3-[[4-(1-methylpyridin-1-ium-4-yl)-1,3-thiazol-2-yl]sulfanyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate. Grades: ≥98%. CAS No. 229016-73-3. Molecular formula: C22H21N8O8PS4. Mole weight: 684.67. | |
| Celikalim | Celikalim is s ATP-sensitive potassium channel agonist originated by Wyeth. It increases K+ outward flux in dog and human airway smooth muscle. But clinical trials for Hypertension, Ischaemic heart disorders and Thrombosis was discontinued. Uses: Hypertension; ischaemic heart disorders; thrombosis. Synonyms: Way-120,491; Way120491; Way-120491; Way 120491; Celikalim;2-[(3S,4R)-3-hydroxy-2,2-dimethyl-6-(trifluoromethoxy)-3,4-dihydrochromen-4-yl]-3H-isoindol-1-one. Grades: 98%. CAS No. 124916-54-7. Molecular formula: C20H18F3NO4. Mole weight: 393.36. | |
| Celiprolol hydrochloride | Celiprolol hydrochloride is a cardioselective β1-adrenergic blocker with potential antianginal and antihypertensive properties. Synonyms: Celiprolol HCl; 3-[3-acetyl-4-[3-(tert-butylamino)-2-hydroxypropoxy]phenyl]-1,1-diethylurea hydrochloride. Grades: 98%. CAS No. 57470-78-7. Molecular formula: C20H33N3O4.HCl. Mole weight: 415.95. | |
| CeMMEC1 | CeMMEC1 is an N-methylisoquinolinone derivative that inhibits the second bromodomain of TAF1 (Kd = 1.8 μM; IC50 = 0.9 μM). It does not bind to either the first or second bromodomain of BRD4. CeMMEC1 can also inhibit the proliferation of THP-1 and H23 lung adenocarcinoma cells. Synonyms: CeMMEC1; 440662-09-9; N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-methyl-1-oxo-1,2-dihydroisoquinoline-4-carboxamide; N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methyl-1-oxoisoquinoline-4-carboxamide; Oprea1_520920; SCHEMBL20942542; BCP19839; EX-A1815; EiM08-22966; AKOS005754739; AC-35499; MS-25094; HY-111445; CS-0040872; Z1863671528; N-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-2-METHYL-1-OXO-1,2-DIHYDRO-4-ISOQUINOLINECARBOXAMIDE. Grades: ≥98%. CAS No. 440662-09-9. Molecular formula: C19H16N2O4. Mole weight: 336.3. | |
| CeMMEC13 | CeMMEC13 is an isoquinolinone and a potent inhibitor of TAF1 bromodomain with IC50 of 2.1 μM. It acts on the bromodomain of TAF1 but does not bind to bromodomains of BRD4, BRD9, or CREBBP. CeMMEC13 synergizes with (+)-JQ1 to inhibit the proliferation of THP-1 and H23 lung adenocarcinoma cells. Synonyms: CeMMEC13; 1790895-25-8; 1-Methyl-2-oxo-1,2-dihydro-quinoline-4-carboxylic acid (2,3-dihydro-benzo[1,4]dioxin-6-yl)-amide; N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1-methyl-2-oxo-1,2-dihydroquinoline-4-carboxamide; CHEMBL4871450; N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-methyl-2-oxoquinoline-4-carboxamide; SCHEMBL20942221; BCP25037; EX-A1816; BDBM50572136; s8329; AKOS027600530; CeMMEC13, >=98% (HPLC); CCG-267868; AC-35506; BS-15617; HY-101088; CS-0020799; C73404; A924884; Z441586532; N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,2-dihydro-1-methyl-2-oxo-4-quinolinecarboxamide. Grades: ≥98%. CAS No. 1790895-25-8. Molecular formula: C19H16N2O4. Mole weight: 336.3. | |
| CeMMEC1 hydrochloride | CeMMEC1 is an N-methylisoquinolinone derivative that inhibits the second bromodomain of TAF1 (Kd = 1.8 μM; IC50 = 0.9 μM). It does not bind to either the first or second bromodomain of BRD4. CeMMEC1 can also inhibit the proliferation of THP-1 and H23 lung adenocarcinoma cells. Synonyms: CeMMEC1 HCl. Grades: ≥98%. CAS No. 2095432-53-2. Molecular formula: C19H17ClN2O4. Mole weight: 372.8. | |
| Censavudine | Censavudine is a nucleoside reverse transcriptase inhibitor. It is active against HIV resistant to both abacavir and tenofovir. It is a candidate for people with multi-drug resistant (MDR) strains of the virus. It is a derivative of stavudine (d4T), but is less toxic. It has demonstrated potent in vitro activity against HIV-2. It was developed by Bristol Myers-Squibb and in clinic phase 2 trials. Uses: Censavudine is active against hiv resistant to both abacavir and tenofovir. Synonyms: OBP-601; OBP601; OBP 601; BMS-986001; BMS 986001; BMS986001; festinavir; 4'-Ed4T; Censavudine; 2',3'-Didehydro-3'-deoxy-4'-ethynylthymidine;4'-Ed4T;4'-Ethynylstavudine;4'-Ethynyl D4T;1-[(2R,5R)-5-ethynyl-5-(hydroxymethyl)-2H-furan-2-yl]-5-methylpyrimidine-2,4-dione. Grades: 98%. CAS No. 634907-30-5. Molecular formula: C12H12N2O4. Mole weight: 248.24. | |
| Centrinone | Centrinone, a pyrimidinamine derivative, has been found to be a high affinity and selective PLK4 inhibitor (Ki = 0.16 nM). Synonyms: Centrinone; LCR-263; LCR 263; LCR263. 2-[[2-Fluoro-4-[[ (2-fluoro-3-nitrophenyl) methyl]sulfonyl]phenyl]thio]-5-methoxy-N- (5-methyl-1H-pyrazol-3-yl) -6- (4-morpholinyl) -4-pyrimidinamine. Grades: ≥98% by HPLC. CAS No. 1798871-30-3. Molecular formula: C26H25F2N7O6S2. Mole weight: 633.65. | |
| Centrinone B | Centrinone B, has been found to be a high affinity and selective PLK4 inhibitor (Ki: 0.6 nM) and exhibit more than 2000-fold selectivity for PLK4 over Aurora A and Aurora B. Synonyms: Centrinone-B; Centrinone B; CentrinoneB; LCR-323; LCR 323; LCR323; 2-[[2-Fluoro-4-[[ (2-fluoro-3-nitrophenyl) methyl]sulfonyl]phenyl]thio]-5-methoxy-N- (5-methyl-1H-pyrazol-3-yl) -6- (1-piperidinyl) -4-pyrimidinamine. Grades: ≥98% by HPLC. CAS No. 1798871-31-4. Molecular formula: C27H27F2N7O5S2. Mole weight: 631.67. | |
| CEP 1347 | CEP 1347, also named KT 7515 or CHEMBL290352, an ethylthiomethyl derivative, is a potent, selective inhibitor of the cJun-amino terminal kinase pathway currently under clinical evaluation for the treatment of neurodegenerative diseases. It blocks Aβ-induced cortical neuron apoptosis (EC50 ~51 nM). Uses: Anti-alzheimer agents; amyloid-β inhibitor. Synonyms: CHEMBL290352; CEP-1347; 3,9-Bis(etsm)-K-252a; CEP1347; 156177-65-0; CEP 1347; KT7515; 3,9-Bis((ethylthio)methyl)-K-252a; KT 7515; KT-7515; GTPL8173; SCHEMBL12047710; BDBM24942; CEP1374; CEP 1374; CEP-1374; ZINC3928304; AKOS024458422; KT-1575; 170587-65-2; 9,12-Epoxy-1H-diindolo(1,2,3-fg:3',2',1'-kl)pyrrolo(3,4-i)(1,6)benzodiazocine-10-carboxylic acid, 5,16-bis((ethylthio)methyl)-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-, methyl ester, (9S-(9alpha,10beta,12alpha))-; CEP 1347|(9S,10R,12R)-5-16-Bis[(ethylthio)methyl]-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester; methyl (15S, 16R, 18R)-10, 23-bis[(ethylsulfanyl)methyl]-16-hydroxy-15-methyl-3-oxo-28-oxa-4, 14, 19-triazaoctacyclo[12.11.2.1^{15, 18}.0^{2, 6}.0^{7, 27}.0^{8, 13}.0^{19, 26}.0^{20, 25}]octacosa-1, 6, 8, 10, 12, 20, 22, 24, 26-nonaene-16-carboxylate. CAS No. 156177-65-0. Molecular formula: C33H33N3O5S2. Mole weight: 615.76. | |
| CEP-14083 | CEP-14083 is a ALK inhibitor. It has a potent activity against ALK in enzymatic assays (IC50 = 11 nmol/L). CEP-14083 can also inhibit the insulin receptor at a concentration within a nanomolar range. In a preclinical assay, CEP-14083 showed it can control the expression of molecules that determine T-cell identity and signaling in lymphoma cells. Synonyms: CEP14083; CEP 14083; CEP-14083. 1-methyl-3-(4-methyl-6-oxo-13-propyl-2,4,6,7,8,13-hexahydro-1H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-10-yl)-1-phenylurea. Grades: 98%. CAS No. 856692-39-2. Molecular formula: C31H30N6O2. Mole weight: 518.61. | |
| CEP-14513 | CEP-14513 is a ALK inhibitor. It shows ALK inhibitory activity in both in vitro enzymatic assay (IC50 = 5 nM) and cell-based assays of ALK tyrosine phosphorylation (IC50 = 30 nM). Synonyms: CEP14513; CEP 14513; CEP-14513. 13-isobutyl-4-methyl-6-oxo-2,4,6,7,8,13-hexahydro-1H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-10-yl 4-(dimethylamino)benzylcarbamate. Grades: 98%. CAS No. 856693-04-4. Molecular formula: C34H36N6O3. Mole weight: 576.69. | |
| CEP-28122 | CEP-28122 is a highly potent and selective oral anaplastic lymphoma kinase inhibitor with antitumor activity in experimental human cancer models. Synonyms: CEP 28122; CEP28122; Bicyclo[2.2.1]hept-5-ene-2-carboxamide, 3-[[5-chloro-2-[[(7S)-6,7,8,9-tetrahydro-1-methoxy-7-(4-morpholinyl)-5H-benzocyclohepten-2-yl]amino]-4-pyrimidinyl]amino]-, (1S,2S,3R,4R)-; (1S,2S,3R,4R)-3-[[5-Chloro-2-[[(7S)-6,7,8,9-tetrahydro-1-methoxy-7-(4-morpholinyl)-5H-benzocyclohepten-2-yl]amino]-4-pyrimidinyl]amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide. Grades: ≥95%. CAS No. 1022958-60-6. Molecular formula: C28H35ClN6O3. Mole weight: 539.07. | |
| CEP-32496 | CEP-32496 is a highly potent inhibitor of BRAF(V600E/WT) and c-Raf with Kd of 14 nM/36 nM and 39 nM, also potent to Abl-1, c-Kit, Ret, PDGFRβ and VEGFR2, respectively; insignificant affinity for MEK-1, MEK-2, ERK-1 and ERK-2. Phase 1/2. Synonyms: 1-(3-((6,7-dimethoxyquinazolin-4-yl)oxy)phenyl)-3-(5-(1,1,1-trifluoro-2-methylpropan-2-yl)isoxazol-3-yl)urea; RXDX-105; RXDX 105; RXDX105; CEP32496; CEP-32496; CEP 32496; AC013773; AC 013773; AC-013773 Agerafenib. Grades: >98%. CAS No. 1188910-76-0. Molecular formula: C24H22F3N5O5. Mole weight: 517.46. | |
| CEP-32496 hydrochloride | CEP-32496, also known as AC013773, is an orally available v-raf murine sarcoma viral oncogene homolog B1 (B-raf) serine/threonine protein kinase inhibitor with potential antineoplastic activity. CEP-32496 specifically and selectively inhibits the activity of the mutated form (V600E) of B-raf kinase. This inhibits the activation of the RAF/mitogen-activated protein kinase kinase (MEK)/extracellular signal-related kinase (ERK) signaling pathway and may result in a decrease in the proliferation of tumor cells expressing the mutated B-raf gene. The Raf mutation BRAF V600E, in which valine is substituted for glutamic acid at residue 600, is frequently found in a variety of human tumors and results in the constitutive activation of the RAF/MEK/ERK signaling pathway that regulates cellular proliferation and survival. Synonyms: CEP-32496; CEP32496; CEP 32496; AC013773; AC 013773; AC-013773. CAS No. 1227678-26-3. Molecular formula: C24H23ClF3N5O5. Mole weight: 553.92. | |
| CEP-37440 | CEP-37440 is an orally available dual kinase inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) and focal adhesion kinase (FAK), with potential antineoplastic activity. Upon administration, ALK-FAK inhibitor CEP-37440 selectively binds to and inhibits ALK kinase and FAK kinase. The inhibition leads to disruption of ALK- and FAK-mediated signal transduction pathways and eventually inhibits tumor cell growth in ALK- and FAK-overexpressing tumor cells. ALK belongs to the insulin receptor superfamily and plays an important role in nervous system development; its dysregulation and gene rearrangements are associated with a variety of tumors. The cytoplasmic tyrosine kinase FAK, a signal transducer for integrins, is upregulated and constitutively activated in various tumor types; it plays a key role in tumor cell migration, proliferation, survival, and tumor angiogenesis. Synonyms: CEP-37440; CEP 37440; CEP37440. CAS No. 1391712-60-9. Molecular formula: C30H38ClN7O3. Mole weight: 580.12. | |
| CEP-40783 | CEP-40783 is an orally-active, nanomolar potent and highly kinase-selective Type II inhibitor of the AXL and c-Met RTK with IC50 values of 7 nM and 12 nM, respectively. Synonyms: N-[4-(6,7-dimethoxyquinolin-4-yl)oxy-3-fluorophenyl]-3-(4-fluorophenyl)-2,4-dioxo-1-propan-2-ylpyrimidine-5-carboxamide; CEP40783; CEP 40783; CEP-40783; RXDX-106; RXDX 106; RXDX106. CAS No. 1437321-24-8. Molecular formula: C31H26F2N4O6. Mole weight: 588.56. | |
| Cephalexin hydrochloride | Cefalexin hydrochloride is a cephalosporin antibiotic. It is a first-generation cephalosporin antibiotic introduced in 1967 by Eli Lilly and Company. It is an orally administered agent with a similar antimicrobial spectrum to the intravenous agents cefalotin and cefazolin. Uses: Anti-bacterial agents. Synonyms: Keflex hydrochloride. Grades: >98%. CAS No. 59695-59-9. Molecular formula: C16H18ClN3O4S. Mole weight: 383.85. | |
| Cephapirin Sodium | Cephapirin is a cephalosporin antibiotic agent. Uses: Anti-bacterial agents. Synonyms: sodium;(6R,7R)-3-(acetyloxymethyl)-8-oxo-7-[(2-pyridin-4-ylsulfanylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; Cephapirin Sodium; Cefapirin sodium; Cephap; BL P 1322; BL-P 1322; BLP 1322. NSC 179171. Grades: Assay: 855 - 1000 ug/mg. CAS No. 24356-60-3. Molecular formula: C17H16N3NaO6S2. Mole weight: 445.44. | |
| Cerdulatinib | Cerdulatinib, also known as PRT2070 and PRT062070, is a novel, oral, dual spleen tyrosine kinase (Syk) and janus kinase (JAK) inhibitor. Cerdulatinib preferentially inhibited JAK1 and JAK3 dependent cytokine mediated signaling and functional responses in various cell types. IL2 mediated STAT5 Y694 was inhibited with an IC50 of 0.27uM, while IL4 mediated signaling to STAT6 Y641 and functional responses in B cells and monocytes, namely CD69, CD25, and CD23 up-regulation, were inhibited with IC50 within the range of 0.11uM to 0.57uM. It is currently being studied in patients with genetically-defined hematologic cancers, as well as for patients who have failed therapy due to relapse or acquired mutations. Synonyms: Cerdulatinib; PRT2070; PRT-2070; PRT 2070; PRT-062070; PRT 062070; PRT062070. CAS No. 1198300-79-6. Molecular formula: C20H27N7O3S. Mole weight: 445.542. | |
| Cerestat | Cerestat, a naphthalenyl-guanidine derivative, which has been found to be a potent and noncompetitive NMDA receptor antagonist(IC50 = 36 nM) and exhibits more than 70-fold selectivity for NMDA receptor over σ receptor. Synonyms: N-(3-Ethylphenyl)-N-methyl-N'-1-naphthalenylguanidine hydrochloride; CNS 1102. Grades: ≥98% by HPLC. CAS No. 137160-11-3. Molecular formula: C20H21N3.HCl. Mole weight: 339.86. | |
| Cetaben | Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors of nuclear hormone receptor superfamily comprising of the following three subtypes: PPARα, PPARγ, and PPARβ/&delta. Cetaben is an unique PPARα-independent peroxisome proliferator with hypolipidemic activity, characterized by reduction in serum triglyceride and cholesterol concentrations in rats. Cetaben has the ability to inhibit cholesterol production in human hepatoma Hep-G2 cells. Synonyms: Hexadecylamino-p-amino benzoic acid. Grades: ≥98%. CAS No. 55986-43-1. Molecular formula: C23H39NO2. Mole weight: 361.6. | |
| Cevimeline | Cevimeline is a selective M1 receptor agonist. Uses: Muscarinic agonists. Synonyms: AF-102B, Cevimeline, FKS 508, HSDB 7286, SNI 2011. Grades: >98%. CAS No. 107233-08-9. Molecular formula: C10H17NOS. Mole weight: 199.31. | |
| Cevipabulin | Cevipabulin, is a small synthetic molecule of triazolopyrimidine derivative with potential antitumor activity. With a novel mechanism of action distinct from the action of other vinca alkaloid compounds, it specifically binds to tubulin at the vinca site, and promotes the polymerization of tubulin into microtubules. Cebipabulin stabilizes tubulin and inhibits microtubule disassembly. This results in cell cycle arrest at the G2/M phase, and leading to cell death. Synonyms: TTI 237; TTI237; TTI237; D06576. CAS No. 849550-05-6. Molecular formula: C18H18ClF5N6O. Mole weight: 464.825. | |
| CFI-401870 | CFI-401870 is a TTK (tyrosine threonine kinase) Inhibitor with IC50 value < 10 nM. CFI-401870 showed low off-target activity (>500×) and microsomal stability (T(1/2) > 30 min). CFI-401870 recapitulated the phenotype of TTK RNAi, demonstrated in vivo tumor growth inhibition upon oral dosing. It has been selected for preclinical evaluation. Uses: Anti-tumor. Synonyms: CFI-401870; CFI 401870; CFI401870; N-((R)-cyclopropyl(pyridin-2-yl)methyl)-3-(4-((1R,3R,5S)-3-hydroxy-8-azabicyclo[3.2.1]octan-8-yl)phenyl)-1H-indazole-5-carboxamide. Grades: 98%. CAS No. 1430741-35-7. Molecular formula: C30H31N5O2. Mole weight: 493.61. | |
| CFM-2 | Potent and selective AMPA antagonist. Synonyms: CFM-2; CFM 2; CFM2. Grades: >98%. CAS No. 178616-26-7. Molecular formula: C17H17N3O3. Mole weight: 311.34. | |
| c-FMS inhibitor | c-FMS inhibitor is a novel c-Fms kinase inhibitor with a potential as anti-inflammatory agent and antirheumatic agent. Synonyms: 1H-Pyrrole-2-carboxamide, 4-cyano-N-[4-(4-methyl-1-piperazinyl)-2-(4-methyl-1-piperidinyl)phenyl]-. Grades: >98%. CAS No. 885704-21-2. Molecular formula: C23H30N6O. Mole weight: 406.52. | |
| CFTRinh-172 | CFTRinh-172 is a voltage-independent, selective CFTR inhibitor with Ki of 300 nM, showing no effects on MDR1, ATP-sensitive K+ channels, or a series of other transporters. Synonyms: CFTR Inh-172; CFTR Inh 172; CFTR Inh172; CFTR(Inh)-172; CFTR(Inh) 172; CFTR(Inh)172; CFTR Inhibitor-172; CFTR Inhibitor 172; CFTR Inhibitor172. Grades: >98%. CAS No. 307510-92-5. Molecular formula: C18H10F3NO3S2. Mole weight: 409.4. | |
| CGH 2466 dihydrochloride | CGH 2466 dihydrochloride is an adenosine A1, A2B and A3 receptor antagonist (IC50 = 19, 21, and 80 nM, respectively). It also displays an inhibitory effect on p38 MAPK (IC50 = 187 - 400 nM) and phosphodiesterase type 4D (IC50 = 22 nM). CGH 2466 is potentially used for the treatment of asthma and chronic obstructive pulmonary disease (COPD). Uses: Potential treatment of asthma and copd. Synonyms: CGH 2466 dihydrochloride; CGH2466 dihydrochloride; CGH-2466 dihydrochloride; 4-(3,4-Dichlorophenyl)-5-(4-pyridinyl)-2-thiazolamine dihydrochloride. Grades: ≥99% by HPLC. CAS No. 1177618-54-0. Molecular formula: C14H9N3SCl2.2HCl. Mole weight: 395.13. | |
| CGP 12177 | CGP 12177 is a partial β3-adrenoceptor agonist with Ki value of 88 nM. It is also an of β1- and β2-adrenoceptors antagonist with Ki values of 0.9 nM and 4 nM for β1-, β2adrenoceptors. CGP12177 can slightly activate L-type Ca2+ current in human ventricular myocytes. Uses: Adrenergic beta-antagonists. Synonyms: CGP 12177; CGP12177; CGP-12177; Tbhpbo; CGP 12177 Hydrochloride; CGP 12177 HCl. 4-[3-[(1,1-Dimethylethyl)amino]2-hydroxypropoxy]-1,3-dihydro-2H-benzimidazol-2-one;64208-32-8(hydrochloride). Grades: 98%. CAS No. 81047-99-6. Molecular formula: C14H21N3O3. Mole weight: 279.34. | |
| CGP 12177 hydrochloride | CGP 12177 hydrochloride is a partial agonist of β3-adrenoceptors, and also an antagonist of β1- and β2-adrenoceptors (Ki = 0.9, 4 and 88 nM for β1, β2 and β3 receptors respectively). Synonyms: CGP 12177 hydrochloride; CGP12177 hydrochloride; CGP-12177 hydrochloride; 4-[3-[(1,1-Dimethylethyl)amino]2-hydroxypropoxy]-1,3-dihydro-2H-benzimidazol-2-one hydrochloride. CAS No. 64208-32-8. Molecular formula: C14H21N3O3.HCl. Mole weight: 315.8. | |
| CGP-12388 | CGP-12388 is a beta-adrenoceptor antagonist-derived radioligands. It is used for cardiac PET imaging due to its high hydrophilicity and affinity to beta-adrenoceptor. Uses: Cgp-12388 is used for cardiac pet imaging due to its high hydrophilicity and affinity to beta-adrenoceptor. Synonyms: 4-(3-(Isopropylamino)-2-Hydroxypropoxy)-2H-Benzimidazol-2-One;Cgp 12388; Cgp-12388; Cgp12388;2H-Benzimidazol-2-one, 4-(3-(isopropylamino)-2-hydroxypropoxy)-;4-[2-hydroxy-3-(propan-2-ylamino)propoxy]benzimidazol-2-one. Grades: 95%. CAS No. 108929-47-1. Molecular formula: C13H19N3O3. Mole weight: 263.29. | |
| CGP 13501 | CGP 13501 is a positive allosteric modulator of GABAB receptors, potentiating the effects of GABA at this receptor type. Uses: Gaba-b receptor agonists. Synonyms: CGP13501; CGP 13501; CGP-13501; 3,5-bis(1,1-Dimethylethyl)-4-hydroxy-α,α-dimethylbenzenepropanal. Grades: ≥98% by HPLC. CAS No. 56189-68-5. Molecular formula: C19H30O2. Mole weight: 290.44. | |
| CGP 20712 dihydrochloride | CGP 20712 dihydrochloride is a potent and selective β1-adrenoceptor antagonist (IC50 = 0.7 nM) with 10,000-fold selectivity over β2-adrenoceptors. Synonyms: CGP 20712A Dihydrochoride; CGP 20712ADihydrochoride; CGP 20712A; CGP20712A; CGP-20712A. SR-01000076208; 1-[2-((3-Carbamoyl-4-hydroxy)phenoxy)ethylamino]-3-[4-(1-methyl-4-trifluoromethyl-2-imidazolyl)phenoxy]-2-propanol dihydrochloride. Grades: ≥96% by HPLC. CAS No. 1216905-73-5. Molecular formula: C23H25F3N4O5.2HCl. Mole weight: 567.39. | |
| Cgp 31358 | CGP 31358 is a compound that can bind to a site on the N-methyl-D-aspartate (NMDA) receptor which is coupled to both the transmitter recognition site and the channel domain.It can be a tool for researching the molecular pharmacology of this receptor-channel complex. Uses: A tool for researching the molecular pharmacology of receptor-channel complex. Synonyms: Cgp 31358; Cgp-31358; Cgp31358; 1-(4-(1-(4-chlorophenyl)-1-methylethyl)-2-methoxyphenyl)-1H-1,2,4-Triazole-3-carboxamide. Grades: 98%. CAS No. 125652-47-3. Molecular formula: C19H19ClN4O2. Mole weight: 370.83. | |
| Cgp-33304 | Cgp-33304 is a dual phospholipase A2 inhibiting agent and leukotriene receptor antagonists. It may prevent hypoxia secondary to leukotriene induced bronchoconstriction in shock states. It has potential to be an useful therapeutic agent in acute ischemic disorders including traumatic shock. Uses: Cgp-33304 has potential to be an useful therapeutic agent in acute ischemic disorders including traumatic shock. Synonyms: Cgp 33304; Cgp33304; Cgp-33304; 1H-Tetrazole-5-carboxamide, N-(5-(3-(4-acetyl-3-hydroxy-2-propylphenox y)propoxy)-4-bromo-2-methylphenyl)-, monosodium salt;CGP33304;N-(3-(3-(4-Acetyl-3-hydroxy-2-n-propylphenoxy)propoxy)-4-bromo-6-methylphenyl)-1H-tetrazole-5-carboxamide sodium;Sodium 5-((5-(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy)-4-bromo-2-methylphenyl)carbamoyl)tetrazol-1-ide. Grades: >98%. CAS No. 111130-14-4. Molecular formula: C23H25BrN5NaO5. Mole weight: 554.38. | |
| CGP 35348 | CGP 35348 is a selective and brain penetrant GABAB receptor antagonist (IC50 = 34 μM as measured in rat cortical membranes) with higher affinity for postsynaptic than presynaptic receptors. Synonyms: CGP35348; CGP-35348; (3-Aminopropyl) (diethoxymethyl)phosphinic acid. CAS No. 123690-79-9. Molecular formula: C8H20NO4P. Mole weight: 225.22. | |
| Cgp-35949 | Cgp-35949 is an LTD4 antagonist which has phospholipase inhibitory activity. It represents a new approach to the treatment of asthma. Uses: Cgp-35949 represents a new approach to the treatment of asthma. Synonyms: Cgp 35949; Cgp-35949; Cgp35949; 1H-Tetrazole-5-carboxamide, N-(5-(3-(4-acetyl-3-hydroxy-2-propylphenox y)propoxy)-4-chloro-2-methylphenyl)-, monosodium salt;CGP35949;N-(5-(3-(4-Acetyl-3-hydroxy-2-propylphenoxy)propoxy)-4-chloro-2-methylphenyl)-1H-tetrazole-5-carboxamide monosodium salt;Sodium N-[5-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]-4-chloro-2-methylphenyl]-1,2,3-triaza-4-azanidacyclopenta-2,5-diene-5-carboxamide;Sodium 5-((5-(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy)-4-chloro-2-methylphenyl)carbamoyl)tetrazol-1-ide. Grades: >98%. CAS No. 111130-13-3. Molecular formula: C23H25ClN5NaO5. Mole weight: 509.92. | |
| CGP 36216 | CGP 36216 hydrochloride is a selective GABAB antagonist that is active to presynaptic receptors but inactive to postsynaptic receptors. Synonyms: CGP 36216 hydrochloride; CGP36216 hydrochloride; CGP-36216 hydrochloride; (3-Aminopropyl)ethylphosphinic acid hydrochloride. Grades: ≥99% by HPLC. CAS No. 123691-29-2. Molecular formula: C5H14NO2P. Mole weight: 151.14. | |
| CGP 36216 hydrochloride | CGP 36216 is a selective GABA antagonist with IC50 of 43 μM, which is active at the presynaptic but not postsynaptic. Synonyms: CGP 36216. Grades: ≥98%. CAS No. 1781834-71-6. Molecular formula: C5H14NO2P·HCl. Mole weight: 187.6. | |
| CGP 37849 | CGP 37849 is a potent, selective and competitive NMDA receptor antagonist (Ki = 35 nM). CGP 37849 exhibits an anticonvulsant effect following oral administration in vivo. Synonyms: CGP37849; CGP 37849; CGP-37849; (E)-(±)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid. Grades: ≥99% by HPLC. CAS No. 127910-31-0. Molecular formula: C6H12NO5P. Mole weight: 209.14. | |
| CGP 39551 | Cgp 39551 is a selective and competitive N-methyl-D-aspartate (NMDA) receptor antagonist originated by Novartis. Ki is 310 nM for inhibition of [3H]-CPP binding in rat brain. CGP 39551 produces excitatory effects and causes psychotomimetic effects in humans. Treatment for Craniocerebral trauma, Epilepsy and Stroke was discontinued. Uses: Craniocerebral trauma, epilepsy and stroke. Synonyms: Cgp 39551; Cgp39551; Cgp-39551; (E)-(+/-)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid ethyl ester;CGP 39551;(E)-(-)-2-amino-4-methyl-5-phosphono-3-pentenoic acid ethyl ester. Grades: 98%. CAS No. 127910-32-1. Molecular formula: C8H16NO5P. Mole weight: 237.19. | |
| Cgp 39653 | Cgp 39653 is a competitive N-Methyl-D-aspartate (NMDA) receptor antagonist. CGP 39653 can selectively bins to the NMDA receptor as an antagonist with high affinity. It is currently the ligand of choice for labeling the NMDA receptor. Uses: The ligand of choice for labeling the nmda receptor. Synonyms: Cgp 39653; Cgp-39653; Cgp-39653; (R,Z)-2-amino-4-(phosphonomethyl)hept-3-enoic acid. Grades: 98%. CAS No. 132472-31-2. Molecular formula: C8H16NO5P. Mole weight: 237.19. | |
| CGP 43487 | CGP 43487 has been found to be a NMDA receptor antagonist and was once studied about its influenment of dopaminergic function as a supplement in the treatment of Parkinson's disease. Synonyms: Cgp 43487; Cgp43487; Cgp-43487; [(E,4R)-4-amino-5-ethoxy-2-methyl-5-oxopent-2-enyl]phosphonic acid. Grades: 98%. CAS No. 146388-56-9. Molecular formula: C8H16NO5P. Mole weight: 237.19. | |
| CGP 46381 | CGP 46381 is a selective GABAB receptor antagonist (IC50 = 4.9 μM). Synonyms: (3-Aminopropyl) (cyclohexylmethyl)phosphinic Acid; P-(3-Aminopropyl)-P-(cyclohexylmethyl)phosphinic Acid. CAS No. 123691-14-5. Molecular formula: C10H22NO2P. Mole weight: 219.26. | |
| CGP 48369 | Cgp 48369 is a nonpeptide a angiotensin type 1 receptor antagonist originated by Novartis. Treatmenf for for Hypertension in Switzerland was discontinued in 1995. Uses: Hypertension. Synonyms: Cgp 48369; Cgp48369; Cgp-48369. 5-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2,6-dibutylpyrimidin-4(1H)-one. Grades: 98%. CAS No. 135689-23-5. Molecular formula: C26H30N6O. Mole weight: 442.56. | |
| CGP 52411 | CGP 52411, also called DAPH, inhibits and reverses the formation of Aβ42 fibers (β-sheet content of aggregated β-amyloid (1-42): IC50 = 4.5 μM) in neurons associated with Alzheimer's disease. And it is also a selective inhibitor of the epidermal growth factor receptor (EGFR) (IC50 = 0.3 μM in vitro). Uses: Anti-alzheimer agents; amyloid-β inhibitor. Synonyms: CGP 52411; CGP52411; CGP-52411; 5,6-dianilinoisoindole-1,3-dione; 406-050-3; Z13D008FZ2; 4,5-dianilinophthalimide; DAPH; Cgp 52411; 5,6-Bis(phenylamino)-1H-isoindole-1,3(2H)-dione; 145915-58-8; Cgp-52411; UNII-Z13D008FZ2; CHEMBL268868; 5,6-dianilino-1h-isoindole-1,3(2h)-dione; CHEBI:53110; Z13D008FZ2; AC1Q6JME; DAPH-1; SCHEMBL11017; 4,5-Bis(anilino)phthalimide; D3943_SIGMA; 4,5-bis-(anilino)phthalimide; AC1L1C19; ZINC6094; DTXSID4040393; CTK8D4606; AAALVYBICLMAMA-UHFFFAOYSA-N; BCPP000288; HMS3260P13; 5,6-dianilinoisoindole-1,3-dione; Tox21_500236; ABP000886; AR-1G6110; BDBM50040929; MFCD00236442; AKOS024457581; BCP9000511; CCG-221540; LP00236; CGP 52411/CGP52411; NCGC00093700-01; NCGC00093700-02; NCGC00093700-03; NCGC00093700-04; NCGC00093700-05; NCGC00260921-01; AK393267; HE062397; HE312151; 5,6-Bis-phenylamino-isoindole-1,3-dione; 5,6-Bis(phenylamino)isoindoline-1,3-dione; J587.895K; 1H-Isoindole-1,3(2H)-dione, 5,6-bis(phenylamino)-; BRD-K13087974-001-01-7; CGP 52411|DAPH|5,6-Bis(phenylamino)-1H-isoindole-1,3(2H)-dione. CAS No. 145915-58-8. Molecular formula: C20H15N3O2. Mole weight: 329.35. | |
| CGP-53153 | CGP-53153 is a steroidal inhibitor of 5 alpha reductase is a steroidal which effects the conversion of testosterone (T) to 5α-dihydrotestosterone (DHT). In vitro, CGP 53153 competitively inhibited rat microsomal 5α-reductase from prostate by 50% (ICs0) at a concentration of 36 nM compared to the reference compound finasteride which inhibited 5α-reductase with an ICs0 of 11 nM in the same system. In vivo, inhibition of 5α-reductase activity was characterized in three different test systems. Synonyms: (1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-(2-cyanopropan-2-yl)-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide; wt1-ricin a; SCHEMBL8823373; CGP 53153; CGP-53153; CGP53153. CAS No. 149281-19-6. Molecular formula: C23H33N3O2. Mole weight: 383.53. | |
| CGP 53353 | CGP 53353, also called DAPH 2, highly selectively inhibits procarcinogenic protein kinase C-βII (PKCβII) ,and it is also an inhibitor of prionogenic Sup35 fibrillization (IC50 ~ 3.4 μM). It inhibits de novo Aβ42 assembly in vitro. Uses: Anti-alzheimer agents; amyloid-β inhibitor. Synonyms: CGP53353; CGP 53353; CGP-53353. 5,6-bis(4-fluoroanilino)isoindole-1,3-dione; DAPH 2; CGP-53353; 145915-60-2; DAPH-7; PKCbetaII/EGFR Inhibitor; CHEMBL7939; 5,6-Bis[(4-fluorophenyl)amino]-2H-isoindole-1,3-dione; 5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE; IN1137; 4,5-bis(4-Fluoroanilino)-phthalimide; CGP 53 353; CG53353; 4,5-Bis(4-fluoroanilino)phthalimide; 4,5-Bis[4-fluoroanilino]phthalimide; PKCbII/EGFR Inhibitor; AC1O8KXF; DAPH-2; MolMap_000016; C7866_SIGMA; SCHEMBL230492; GTPL5163; CTK8E9235; RONQPWQYDRPRGG-UHFFFAOYSA-N; HMS3229K07; HMS3269E05; ZINC600430; CGP53353; BDBM50040930; CGP 53353; DNC003638; MFCD00938569; AKOS015911570; CCG-206784; NCGC00159569-01; NCGC00159569-02; AK394840; HE005407; HE312152; ZB014534; DB-042814; FT-0643387; 5,6-bis(4-fluoroanilino)isoindole-1,3-dione; 5,6-Bis((4-fluorophenyl)amino)isoindoline-1,3-dione; 5,6-Bis-(4-fluoro-phenylamino)-isoindole-1,3-dione; BRD-K32292990-001-01-0; I14-37922; 5,6-bis[(4-fluorophenyl)amino]-2,3-dihydro-1H-isoindole-1,3-dione; CGP 53353|5,6-bis[(4-Fluorophenyl)amino]-1H-isoindole-1,3(2H)-dione. CAS No. 145915-60-2. Molecular formula: C20H13F2N3O2. Mole weight: 365.34. | |
| CGP 53820 | CGP 53820 has been found to be a HIV-1 Protease pseudosymmetric inhibitor that could probably be effective in the treatment of HIV infections. Synonyms: Cgp 53820; Cgp-53820; Cgp53820; (2S)-2-acetamido-N-[(2S,3S)-4-[[[(2S)-2-acetamido-3-methylbutanoyl]amino]-(cyclohexylmethyl)amino]-3-hydroxy-1-phenylbutan-2-yl]-3-methylbutanamide. Grades: 98%. CAS No. 149267-24-3. Molecular formula: C31H51N5O5. Mole weight: 573.78. | |
| CGP 54626 hydrochloride | The hydrochloride salt form of CGP 54626, a dichloropheny derivative, has been found to be a GABAB receptor antagonist that could probably be effective as an analgesic agent. IC50: 4 nM. Synonyms: CGP 54626 hydrochloride; CGP54626 hydrochloride; CGP-54626 hydrochloride; CGP 54626 HYDROCHLORIDE;[S-(R*,R*)]-[3-[[1-(3,4-DICHLOROPHENYL)ETHYL]AMINO]-2-HYDROXYPROPYL](CYCLOHEXYLMETHYL) PHOSPHINIC ACID HYDROCHLORIDE;(S-(R*,R*))-(3-((1-(3,4-Dichlorophenyl)ethyl)amino)-2-hydroxypropyl)-([3.4-3H]-cyclohexylmethyl)phosphinicacid;[3. Grades: 98%. CAS No. 149184-21-4. Molecular formula: C18H28Cl2NO3P.HCl. Mole weight: 410.31. | |
| CGP 55845 hydrochloride | CGP 55845 hydrochloride is a potent and selective GABAB receptor antagonist (IC50 = 5 nM), which prevents agonist binding (pKi = 8.35) and inhibits release of GABA and glutamate (pEC50 = 8.08 and 7.85, respectively). Synonyms: CGP 55845 HCl; CGP 55845HCl; CGP 55845; CGP55845; CGP-55845; (2S)-3-[[ (1S)-1- (3, 4-Dichlorophenyl)ethyl]amino-2-hydroxypropyl] (phenylmethyl)phosphinic acid hydrochloride. Grades: ≥98% by HPLC. CAS No. 149184-22-5. Molecular formula: C18H22Cl2NO3P.HCl. Mole weight: 438.71. | |
| CGP 57813 | CGP 57813 has been found to be a HIV-1 protease inhibitor that has been once developed by Novartis. Synonyms: Cgp 57813; Cgp-57813; Cgp57813; Carbamic acid, (2-hydroxy-4- ( (4-methoxyphenyl) methyl) -5- ( (2-methyl-1- ( ( (2- (4-morpholinyl) -2-oxo-1- (phenylmethyl) ethyl) amino) carbonyl) propyl) amino) -5-oxo-1- (phenylmethyl) pentyl) -, 1,1-dimethylethyl ester, (1S-(1R*,2R*,4S*,5(. Grades: 98%. CAS No. 150608-41-6. Molecular formula: C43H58N4O8. Mole weight: 758.94. | |
| CGP-59326 | CGP-59326, a pyrrolopyrimidine derivative, has been found to be an EGFR antagonist and could used in antineoplastic studies. Synonyms: CGP-59326; CGP 59326; CGP59326; CHEMBL306081; 1H-Pyrrolo(2,3-d)pyrimidin-4-amine, N-(3-chlorophenyl)-5,6-dimethyl-; 7H-Pyrrolo(2,3-d)pyrimidin-4-amine, N-(3-chlorophenyl)-5,6-dimethyl-. Grades: 98%. CAS No. 173458-56-5. Molecular formula: C14H13ClN4. Mole weight: 272.73. | |
| CGP60474 | CGP60474 is a promising inhibitor of PKC with a high degree of selectivity versus other serine/threonine and tyrosine kinases and show competitive kinetics relative to ATP. Synonyms: CGP-60474; CGP 60474. Grades: >98%. CAS No. 164658-13-3. Molecular formula: C18H18ClN5O. Mole weight: 355.82. | |
| CGP74514A | CGP74514A is a cell permeable Cdk inhibitor selective for Cyclin-dependent kinase-1 (Cdk1) (IC50=25nM). CGP74514A was also reported also to affect the activities of other kinases including PKCα (IC50=6.1μM), PKA (IC50=125μM) and EGFR (IC50>10μM), but only at much higher concentrations. Synonyms: 2-N-[(1R,2S)-2-aminocyclohexyl]-6-N-(3-chlorophenyl)-9-ethylpurine-2,6-diamine; CGP 74514A; 481724-82-7 (CGP74514A HCl salt); CGP-74514A; CGP74514A; N(2)-(2-aminocyclohexyl)-N(6)-(3-chlorophenyl)-9-ethyl-9H-purine-2,6-diamine. Grades: >98%. CAS No. 190653-73-7. Molecular formula: C19H24ClN7. Mole weight: 385.9. | |
| CGP 74514 dihydrochloride | CGP 74514 Dihydrochloride is a potent cdk1 inhibitor with IC50 of 25 nM. It can reduce Akt phosphorylation and increase mitochondrial damage in leukemia cells. Synonyms: CGP 74514. Grades: ≥98%. Molecular formula: C19H24ClN7·2HCl. Mole weight: 458.82. | |
| CGP 78608 hydrochloride | CGP 78608 hydrochloride is a potent and selective NMDA antagonist with > 500-fold selectivity over kainate and AMPA receptors (IC50 = 2.7 and 3 μM, respectively). CGP 78608 exhibits an anticonvulsant effect in vivo following systemic administration. Synonyms: CGP78608 hydrochloride; CGP-78608 hydrochloride; [ (1S) -1-[[ (7-Bromo-1, 2, 3, 4-tetrahydro-2, 3-dioxo-5-quinoxalinyl) methyl]amino]ethyl]phosphonic acid hydrochloride; Phosphonic acid, P-[(1S)-1-[[(7-bromo-1,2,3,4-tetrahydro-2,3-dioxo-5-quinoxalinyl)methyl]amino]ethyl]-, hydrochloride (1:1); (S)-(1-(((7-Bromo-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)methyl)amino)ethyl)phosphonic acid hydrochloride. Grades: ≥98% by HPLC. CAS No. 1135278-54-4. Molecular formula: C11H13BrN3O5P.HCl. Mole weight: 414.58. | |
| CGP7930 | CGP7930 is a positive allosteric modulator at the GABAB receptor. It has anxiolytic effects in animal studies, and has a synergistic effect with GABAB agonists such as baclofen and GHB. It increases the potency and efficacy of GABA at both native and recombinant GABAB receptors with EC50 values of 5.37 and 4.60μM respectively. It also enhances the inhibitory effect of the agonist L-baclofen in cultured cortical neurons. It reduces operant self-administration of ethanol and cocaine in rats. Uses: Cgp7930 has anxiolytic effects in animal studies, and has a synergistic effect with gabab agonists such as baclofen and ghb. it reduces operant self-administration of ethanol and cocaine in rats. Synonyms: 3,5-Bis(1,1-dimethylethyl)-4-hydroxy-beta,beta-dimethylbenzenepropanol;2,6-Ditert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol;3-(3',5'-Di-tert-butyl-4'-hydroxy)phenyl-2,2-dimethylpropanol;CGP7930; CGP-7930; CGP 7930. Grades: >98 %. CAS No. 57717-80-3. Molecular formula: C19H32O2. Mole weight: 292.46. | |
| CGP-79807 | CGP-79807 is a potent CDC2 protein kinase inhibitor that originated by Novartis. In Sep 2000, Preclinical development for Cancer in Switzerland was on-going, but no development has been reported. Uses: Cancer. Synonyms: CGP-79807; CGP 79807; CGP79807; UNII-532R2SRL4B; CHEMBL172140; 532R2SRL4B; SCHEMBL5842014; SCHEMBL5842019; BDBM50073763. 3-((9-ethyl-2-((trans-4-hydroxycyclohexyl)amino)-9H-purin-6-yl)amino)-Benzonitrile. Grades: 98%. CAS No. 1229665-91-1. Molecular formula: C20H23N7O. Mole weight: 370.44. | |
| CGS 12066B dimaleate | CGS 12066B dimaleate is a 5-HT1B full agonist, which is 10-fold selective over 5-HT1A and 1000-fold selective over 5-HT2C receptors. Uses: Serotonin receptor agonists. Synonyms: CGS 12066B dimaleate; CGS12066B dimaleate; CGS-12066B dimaleate; 7-Trifluoromethyl-4-(4-methyl-1-piperazinyl)pyrrolo[1,2-a]-quinoxaline dimaleate. Grades: ≥98% by HPLC. CAS No. 109028-10-6. Molecular formula: C17H17F3N4.2C4H4O4. Mole weight: 566.49. | |
| CGS 19755 | CGS 19755 is a potent and competitive NMDA receptor antagonist with anticonvulsant, anxiolytic, analgesic and neuroprotective activity. Synonyms: CGS-19755; CGS 19755; CGS19755; CPDD 0027; CPDD-0027; CPDD0027; Selfotel; cis-4-[Phosphomethyl]-piperidine-2-carboxylic acid. CAS No. 110347-85-8. Molecular formula: C7H14NO5P. Mole weight: 223.17. | |
| CGS 20625 | CGS 20625 is a partial agonist for the benzodiazepine binding site of the GABAA receptor used as an anti-anxiety drug. It acts as a central benzodiazepine receptor agonist (IC50 = 1.3 nM) with no affinity for other neurotransmitter receptor binding sites. Uses: Anti-anxiety drug. Synonyms: CGS 20625; CGS20625; CGS-20625; 5, 6, 7, 8, 9, 10-Hexahydro-2- (4-methoxyphenyl) cyclohepta[b]pyrazolo[3, 4-d]pyridin-3 (2H) -one. Grades: ≥99% by HPLC. CAS No. 111205-55-1. Molecular formula: C18H19N3O2. Mole weight: 309.36. | |
| CGS 9343B | CGS 9343B is a calmodulin (CaM) antagonist that inhibits calmodulin-stimulated cAMP phosphodiesterase activity (IC50 = 3.3 nM). It also prevents estrogen-induced transcription activation by ER, reversibly blocks voltage-activated Na+, Ca2+ and K+ currents in PC12 cells and inhibits nAChR. Synonyms: CGS 9343B; CGS9343B; CGS-9343B; Zaldaride Maleate; 1,3-Dihydro-1-[1-[(4-methyl-4H,6H-pyrrolo[1,2-a][4,1]benzoxazepin-4-yl)methyl]-4-piperidinyl]-2H-benzimidazol-2-one maleate. Grades: ≥98% by HPLC. CAS No. 109826-27-9. Molecular formula: C26H28N4O2.C4H4O4. Mole weight: 544.61. | |
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