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DL-Phenylalanine benzyl ester 4-toluenesulfonate salt
Pyroglutamic acid (also known as PCA, 5-oxoproline, pidolic acid, or pyroglutamate for its basic form) is an uncommon and little studied amino acid derivative in which the free amino group of glutamic acid or glutamine cyclizes to form a lactam. It is a metabolite in the glutathione cycle that is converted to glutamate by 5-oxoprolinase. Pyroglutamate is found in many proteins including bacteriorhodopsin. N-terminal glutamic acid and glutamine residues can spontaneously cyclize to become pyroglutamate. This is one of several forms of blocked N-terminals which present a problem for N-terminal sequencing using Edman chemistry, which requires a free primary amino group not present in pyroglutamic acid. The enzyme pyroglutamate aminopeptidase can restore a free N-terminus by cleaving off the pyroglutamate residue. Synonyms: DL-Pyroglutamic acid; 149-87-1; 5-Oxopyrrolidine-2-carboxylic acid; 2-Pyrrolidone-5-carboxylic acid; 5-Oxo-DL-proline; 5-OXOPROLINE; DL-Proline, 5-oxo-; DL-2-Pyrrolidone-5-carboxylic acid; DL-Glutamic Acid Lactam; dl-pyrrolidonecarboxylic acid; 6VT1YZM21H; CHEBI:16010; D-(+)-Pyroglutamic Acid; MFCD00064322; NSC-40887; OXOPROLINE; DL-Pidolic acid; 5-Oxo-L-proline-d5; UNII-6VT1YZM21H; DL-5-Oxoprolin. Grade: ? 95%. CAS No. 149-87-1. Molecular formula: C5H7NO3. Mole weight: 129.11.
DL-tryptophan amide hydrochloride. Uses: An amino acid amide used as a substrate for studying the action of aminopeptidase enzyme. note: the isomer l-tryptophanamide, hydrochloride is also available as catalogue number t895505. Synonyms: DL-Trp-NH2 HCl; 2-amino-3-(1H-indol-3-yl)propanamide hydrochloride. Grade: ≥ 99% (TLC). CAS No. 67607-61-8. Molecular formula: C11H13N3O·HCl. Mole weight: 239.70.
D-Lys(Cbz)-NCA is widely used as a precursor for the synthesis of polypeptides. Synonyms: N6-Carbobenzoxy-D-lysine-N-Carboxyanhydride; N-ε-Benzyloxycarbonyl-D-lysine Carboxyanhydride. CAS No. 68199-92-8. Molecular formula: C15H18N2O5. Mole weight: 306.31.
D-Lysine is the unnatural isomer of L-Lysine that has the ability to reduce non-enzymatic glycation in vitro. D-Lysine also exists as polypeptide chains of poly-D-lysine, a nonspecific adhesion-promoting molecule that has the potential to be a polymeric drug carrier. Synonyms: D-2,6-Diaminohexanoic acid; (R)-2,6-Diaminocaproic acid; (2R)-2,6-diaminohexanoic acid; H-D-Lys-OH; D-Lys; H D Lys OH. Grade: ≥ 99.5% (Chiral HPLC). CAS No. 923-27-3. Molecular formula: C6H14N2O2. Mole weight: 146.19.
D-Lysine hydrochloride
D-Lysine hydrochloride is a chiral resolution reagent to separate racemic compounds into different mirror isomers and is an important tool for the production of optically active drugs. Synonyms: D-Lys-OH HCl; (R)-2,6-Diaminohexanoic acid monohydrochloride. CAS No. 7274-88-6. Molecular formula: C6H14N2O2·HCl. Mole weight: 182.66.
D-Lys(tfa)-NCA
Applications: N-[4-[(4R)-2,5-Dioxo-4-oxazolidinyl]butyl]-2,2,2-trifluoroacetamide is used in the preparation of phosphate-binding particles which are used to reduce the phosphate level in patients with chronic kidney diseases. Synonyms: Acetamide, N-[4-[(4R)-2,5-dioxo-4-oxazolidinyl]butyl]-2,2,2-trifluoro-; (R)-N-(4-(2,5-Dioxooxazolidin-4-yl)butyl)-2,2,2-trifluoroacetamide. CAS No. 1809273-81-1. Molecular formula: C9H11F3N2O4. Mole weight: 268.19.
D-Lys(Z)-Pro-Arg-pNA
D-Lys(Z)-Pro-Arg-pNA is a luminescent substrate of activated protein C (APC). Synonyms: Chromozym Pca; (5(R)-Amino-6-{2(S)-[4-guanidino-1-(4-nitro-phenylcarbamoyl)-butylcarbamoyl]-pyrrolidin-1(S)-yl}-6-oxo-hexyl)-carbamic acid benzyl ester; L-Argininamide, N6-[(phenylmethoxy)carbonyl]-D-lysyl-L-prolyl-N-(4-nitrophenyl)-; d-Lys(Z)-PR-pNA. Grade: ≥95%. CAS No. 108963-69-5. Molecular formula: C31H43N9O7. Mole weight: 653.73.
D-Lys(Z)-Pro-Arg-pNA diacetate
D-Lys(Z)-Pro-Arg-pNA diacetate is a chromogenic substrate. Synonyms: Spectrozyme PCa; Chromozym Pca diacetate; H-D-Lys(Cbz)-Pro-Arg-pNA.diacetate; d-Lys(Z)-P-R-pNA.diacetate; N6-[(Benzyloxy)carbonyl]-D-lysyl-L-prolyl-N-(4-nitrophenyl)argininamide acetate (1:2). Grade: ≥95%. CAS No. 108963-70-8. Molecular formula: C31H43N9O7.2C2H4O2. Mole weight: 773.83.
Dm-AMP1
DmAMP1, an antifungal plant defensin from dahlia (Dahlia merckII), interacts with sphingolipids from Saccharomyces cerevisiae.
DMPC (1,2-Dimyristoyl-sn-glycero-3-phosphocholine) is a synthetic phospholipid utilized in liposomes and lipid bilayers for the study of biological membranes. Synonyms: 1,2-Dimyristoyl-sn-glycero-3-PC; 1,2-Ditetradecanoyl-sn-glycero-3-phosphocholine; (R)-2,3-Bis(tetradecanoyloxy)propyl [2-(Trimethylammonio)ethyl] Phosphate. Grade: > 97.0% (T) (HPLC). CAS No. 18194-24-6. Molecular formula: C36H72NO8P. Mole weight: 677.93.
DMPE
DMPE (1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine) is a high purity phospholipid utilized for liposome production. Synonyms: 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine. Grade: ≥98%. CAS No. 998-07-2. Molecular formula: C33H66NO8P. Mole weight: 635.85.
DNA-binding protein RFX6 (414-431)
DNA-binding protein RFX6 (414-431) is a truncated fragment of DNA-binding protein RFX6. DNA-binding protein RFX6 is a transcription factor required to direct islet cell differentiation during endocrine pancreas development. Synonyms: Regulatory factor X 6 (414-431); Regulatory factor X domain-containing protein 1 (414-431).
DNA-dependent protein kinase catalytic subunit (2836-2844)
DNA-dependent protein kinase catalytic subunit (2836-2844) is a peptide derived from DNA-dependent protein kinase catalytic subunit. PRKDC (DNA-PKcs) mutations were found in 3 out of 10 of endometriosis-associated ovarian cancers, as well as in the field defects from which they arose. They were also found in 10% of breast and pancreatic cancers. Synonyms: DNA-PK catalytic subunit (2836-2844); DNA-PKcs (2836-2844).
DNA ligase 3 isoform alpha precursor (790-806)
DNA ligase 3 isoform alpha precursor (790-806) is a bioactive peptide of DNA ligase 3 isoform alpha precursor. DNA ligases are critical enzymes of DNA metabolism. DNA ligase 3 isoform alpha is involved in repair and recombination.
DNA repair protein RAD50 (1281-1289)
A fragment of DNA repair protein RAD50. RAD50 is a component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. This peptide can be used in Ovarian carcinoma research.
D-Norvalinol (CAS# 80696-30-6) is a useful research chemical compound. Synonyms: H-D-Nva-ol; (R)-2-Amino-1-pentanol; (R)-2-Aminopentan-1-ol; (R)-(-)-2-Amino-1-pentanol; (2R)-2-aminopentan-1-ol. Grade: ≥ 98 %. CAS No. 80696-30-6. Molecular formula: C5H13NO. Mole weight: 103.17.
Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2
Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2 is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1) and MMP-9. It is cleaved to release the fluorescent moiety N-methylanthranilic acid (Nma), of which the fluorescence can be used to quantify MMP-1 and MMP-9 activity. Synonyms: Matrix Metalloproteinase-1/Matrix Metalloproteinase-9 Fluorogenic Substrate; MMP-1/MMP-9 Fluorogenic Substrate; 1-(2,4-dinitrophenyl)-L-prolyl-3-cyclohexyl-L-alanylglycyl-S-methyl-L-cysteinyl-L-histidyl-L-alanyl-N6-[2-(methylamino)benzoyl]-L-lysinamide. Grade: ≥95%. CAS No. 150956-92-6. Molecular formula: C49H68N14O12S. Mole weight: 1077.23.
Dnp-PLGMWSR
Dnp-PLGMWSR is a fluorogenic substrate for matrix metalloproteinase-2 (MMP-2) and MMP-9. Synonyms: Dnp-Pro-Leu-Gly-Met-Trp-Ser-Arg-OH; Matrix Metalloproteinase-2/Matrix Metalloproteinase-9; Fluorogenic Substrate I; MMP-2/MMP-9 Fluorogenic Substrate I. CAS No. 135662-07-6. Molecular formula: C44H61N13O13S. Mole weight: 1012.1.
DODMA is a cationic lipid containing the unsaturated oleic acid. It can be used in formulation of liposomes for drug delivery system. Synonyms: 1-Propanamine, N,N-dimethyl-2,3-bis[(9Z)-9-octadecenyloxy]-; 1,2-Dioleyloxy-3-dimethylamino-propane; ACMC-20m6xx; ACMC-20m7p2; 1-Propanamine, N,N-dimethyl-2,3-bis[(9Z)-9-octadecenyloxy]-, (2S)-; (2,3-bis-octadec-9-enyloxypropyl)-dimethylamine; 1,2-dioleyloxy-N,N-dimethylaminopropane; N-[2,3-Di(oleyloxy)propyl]-N,N-dimethylamine; 2,3-Dioleyloxy-1-(dimethylamino)propane; 2-amino-2,3-dimethyloleanol; 2,3-Dioleyloxy-1-(dimethylamino)propane. Grade: >98% by HPLC. CAS No. 104162-47-2. Molecular formula: C41H81NO2. Mole weight: 620.08.
Dolabellanin-B2
Dolabellanin-B2 has antibacterial activity against Gram-negative bacteria E.coli JM109 and DH5-alpha, H.influenza IID 983, and V.vulnificus RIMD 2219009. Dolabellanin-B2 has antibacterial activity against Gram-positive bacteria S.aureus IID 1677, B.subtilis RIMD 0225014 and L.monocytogenes VIU206. It also possesses antifungal activity against S.cerevisiae A581A, S.pombe IFO 1628, C.albicans and TIMM-1623, and C.tropicalis TIMM-0313.
Dominulin-A
Dominulin A has antibacterial activity. The source of Dominulin A is the social paper wasp, Polistes dominulus. Grade: >97% by HPLC.
Dominulin-B
Dominulin-B shows antimicrobial activity against the Gram-positive bacteria B.subtilis, and the Gram-negative bacteria E.coli JM109 (MIC=8 μg/ml).
DOPC
DOPC (1,2-Dioleoyl-sn-glycero-3-phosphocholine) is a high purity phospholipid utilized for liposome production. Uses: Dopc has been used for the reconstitution of proteoliposome (pl), used in the preparation of lipid vesicles. Synonyms: 1,2-Dioleoyl-sn-glycero-3-PC; 1,2-dioleoyl-sn-glycero-3-phosphatidylcholine; sn-3-Dioleoyllecithin; 1,2-DOPC; PDD 111; 18:1 PC. Grade: > 97.0% (T) (HPLC). CAS No. 4235-95-4. Molecular formula: C44H84NO8P. Mole weight: 786.11.
DOPG
DOPG is a phosphatidylglycerol in which the phosphatidyl acyl groups are both oleoyl. It has been used to physically stabilize emulsions and suspensions. It is also used in formulations of pulmonary surfactants, intravenous fat emulsions, and oral solutions. Synonyms: Dioleoyl phosphatidylglycerol; 1,2-Dioctadecenoyl-sn-glycero-3-[phospho-rac-(1-glycerol)]; C18:1 phosphatidylglycerol; C18:1 PG; DOPG; 3-{[(2,3-dihydroxypropoxy)(hydroxy)phosphoryl]oxy}-2-[(9Z)-octadec-9-enoyloxy]propyl (9Z)-octadec-9-enoate. Grade: ≥95% by HPLC. CAS No. 62700-69-0. Molecular formula: C42H79O10P. Mole weight: 775.04.
DOPS
DOPS (1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium salt) is high purity phospholipid utilized for liposome production. Synonyms: (2S,8R,19Z)-2-amino-5-hydroxy-11-oxo-8-[[(9Z)-1-oxo-9-octadecenyl]oxy]-4,6,10-trioxa-5-phosphaoctacos-19-enoic acid, 5-oxide, monosodium salt; L-α-Phosphatidyl-L-serine, dioleoyl sodium salt; 1,2-Dioleoyl-sn-Glycero-3-Phosphatidylserine Na salt; 18:1 PS. Grade: >98%. CAS No. 90693-88-2. Molecular formula: C42H77NO10P; Na. Mole weight: 810.03.
DOTA(allyl ester)3, a protected DOTA derivative, is used for coupling to acid- or base-sensitive compounds. Synonyms: DOTA(OAll)3; 4,7,10-Tri-(allyloxycarbonylmethyl)-1,4,7,10-tetraazacyclododecan-1-yl-acetic acid; 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid 1,4,7-triallyl ester; 2-(4,7,10-tris(2-(allyloxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecan-1-yl)acetic acid; {4,7,10-Tris[2-(allyloxy)-2-oxoethyl]-1,4,7,10-tetraazacyclododecan-1-yl}acetic acid. Molecular formula: C25H40N4O8. Mole weight: 524.61.
DOTA-LM3
DOTA-LM3 is a somatostatin receptor (SSTR) antagonist. DOTA-LM3 can be labeled with 177Lu and 68Ga for imaging and detecting tumors. Synonyms: DOTA-Cpa-(D-Cys)-Tyr-[D-Aph(Cbm)]-Lys-Thr-Cys-(D-Tyr)-NH2 [Disulfide Bond (D-Cys)2/Cys7]; DOTA-Cpa-D-Cys-Tyr-D-Aph(Cbm)-Lys-Thr-Cys-D-Tyr-NH2 [Disulfide Bond (D-Cys)2/Cys7]. CAS No. 1192362-32-5. Molecular formula: C69H93ClN16O19S2. Mole weight: 1550.16.