BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| CH0076989 | CH0076989 is a small molecule agonist for CCR3. It activates a number of signalling pathways including chemotaxis and receptor internalisation. Uses: Ch0076989 activates a number of signalling pathways including chemotaxis and receptor internalisation. Synonyms: CH-0076989; CH 0076989; CH0076989; UNII-9E629B19WL; CHEMBL485834; 9E629B19WL;4-(2-(Benzofuran-4-yl)acetamido)-2-bromo-1-(3-phenylpropyl)pyridin-1-ium bromide. Grades: 98%. CAS No. 54371-52-9. Molecular formula: C24H22Br2N2O2. Mole weight: 530.25. |  |
| CH 275 | CH 275 is a potent somatostatin receptor 1 (sst1) agonist (IC50 = 30.9 nM, 345 nM, > 1 μM, > 10 μM and > 10μM for human sst1, sst3, sst4, sst2 and sst5 respectively). It attenuates somatostatin release in the rat nucleus accumbens. Synonyms: CH 275; CH275; CH-275. CAS No. 174688-78-9. Molecular formula: C74H96N14O15S2. Mole weight: 1485.8. | |
| CH5132799 | CH5132799 is a novel class I PI3K inhibitor, which exhibited a strong inhibitory activity especially against PI3K; (IC(50)=0.014 uM). In human tumor cell lines with PI3K pathway activation, CH5132799 showed potent antiproliferative activity. CH5132799 is orally available and showed significant antitumor activity in PI3K pathway-activated human cancer xenograft models in mice. Synonyms: CH5132799; CH-5132799; CH 5132799; PA-799; PA799; PA-799. CAS No. 1007207-67-1. Molecular formula: C15H19N7O3S. Mole weight: 377.423. | |
| CH5137291 | CH5137291 is a potent androgen receptor (AR) pure antagonist which did not produce the agonist metabolite with AR nuclear translocation-inhibiting activity. It inhibits the growth of castration-resistant prostate cancer cells. It offers a novel therapeutic approach against major types of castration-resistant prostate cancers. Uses: Ch5137291 offers a novel therapeutic approach against major types of castration-resistant prostate cancers. Synonyms: CH-5137291; CH 5137291;CH5137291; UNII-A5ZX7J376H; A5ZX7J376H; CHEMBL1290098. 6-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)pyridine-2-sulfonamide. Grades: >98 %. CAS No. 1043446-39-4. Molecular formula: C18H14F3N5O3S2. Mole weight: 469.46. | |
| CH5138303 | CH5138303 is a novel and potent Hsp90 inhibitor. CH5138303 showed high binding affinity for N-terminal Hsp90α (Kd = 0.52 nM) and strong in vitro cell growth inhibition against human cancer cell lines (HCT116 IC50=0.098 μM, NCI-N87 IC50=0.066 μM) and also displayed high oral bioavailability in mice (F = 44.0%) and potent antitumor efficacy in a human NCI-N87 gastric cancer xenograft model (tumor growth inhibition=136%). Synonyms: CH-5138303; CH 5138303. Grades: >98%. CAS No. 959763-06-5. Molecular formula: C19H18ClN5O2S. Mole weight: 415.90. | |
| CH7057288 | CH7057288 is a selective TRK inhibitor that may be useful in inhibiting TRK fusion-positive cancer cell growth with IC50 values of 1.1 nM, 7.8 nM and 5.1 nM for TRKA, TRKB, and TRKC respectively. TRK receptor tyrosine kinases are expressed as fusion proteins encoded by various fusion genes across a wide variety of cancer types, including lung and colorectal cancer. Synonyms: N-tert-butyl-2-[2-[6,6-dimethyl-8-(methylsulfonylamino)-11-oxidanylidene-naphtho[2,3-b][1]benzofuran-3-yl]ethynyl]-6-methyl-pyridine-4-carboxamide; HY-107362; CS-0028214; RCH. CAS No. 2095616-82-1. Molecular formula: C32H31N3O5S. Mole weight: 569.67. | |
| Charybdotoxin trifluoroacetate salt | Charybdotoxin is a specific inhibitor of the big conductance Ca2+-activated K+ channel which is originally isolated from the scorpion L. quinquestriatus. It blocks large-conductance Ca2+-activated K+ channels (BKCas) in GH3 rat pituitary tumor cells and primary bovine aortic smooth muscle cells (Kds = 2.1 and ~2.1 nM, respectively). Synonyms: ChTX. Grades: ≥95%. Molecular formula: C176H277N57O55S7·xCF3COOH. Mole weight: 4295.90. | |
| Chebulagic acid | Chebulagic acid is a polyphenol and tannin that has been found in T. chebula and has diverse biological activities. It is an inhibitor of COX-1, COX-2, and 5-lipoxygenase (5-LO; IC50s = 15, 0.92, and 2.1 μM, respectively) as well as α-glucosidase and 15-LO (IC50s = 0.05 and 24.9 μM, respectively). Chebulagic acid inhibit the LPS-induced upregulation of TNF-α and IL-1β in a dose- and time-dependent manner. And it can also inhibit the production of NO, prostaglandin E2 (PGE2), and reactive oxygen species (ROS), and nuclear translocation of NF-κB in RAW 264.7 macrophages in a concentration-dependent manner. Chebulagic acid also show a protective effect against 1-methyl-4-phenylpyridinium (MPP+) - induce cytotoxicity which mimics the pathological symptom of Parkinson's disease. Uses: Topoisomerase i inhibitors. Synonyms: β-D-glucopyranose; Cyclic 3,6-[(1R)-4,4',5,5',6,6'-hexahydroxy[1,1'-biphenyl]-2,2'-dicarboxylate] 1-(3,4,5-trihydroxybenzoate); Cyclic 2?2:4?1-ester with (2S)-2-[(3S,4S)-5-carboxy-3,4-dihydro-3,7,8-trihydroxy-2-oxo-2H-1-benzopyran-4-yl]butanedioic acid. Grades: ≥98%. CAS No. 23094-71-5. Molecular formula: C41H30O27. Mole weight: 954.66. | |
| Chelidonic acid | Chelidonic acid is a secondary metabolite found in several plants with therapeutic potential in allergic disorders in experimental animals. It is used as a mild analgesic, an antimicrobial, an acentral nervous system sedative. Chelidonic acid also shows anti-inflammatory activity and has potential to inhibit IL-6 production by blocking NF-κB and caspase-1. Chelidonic acid is a glutamate decarboxylase inhibitor, with a Ki of 1.2 μM. Synonyms: 4-oxopyran-2,6-dicarboxylic acid. CAS No. 99-32-1. Molecular formula: C7H4O6. Mole weight: 184.10. | |
| CHF-4227 | CHF-4227 is a selective estrogen receptor modulator, binds with high affinity to the human estrogen receptor-alpha and -beta (dissociation constant K(I) = 0.017 and 0.099 nM, respectively). Uses: Estrogen receptor modulator. Synonyms: CHF4227; CHF 4227; CHF-4227; 3-(4-methoxyphenyl)-4-(4-(2-(piperidin-1-yl)ethoxy)benzyl)-2H-chromen-7-ol. Grades: ≥98%. CAS No. 444643-64-5. Molecular formula: C30H33NO4. Mole weight: 471.59. | |
| CHF-6001 | This active molecular is a Type 4 cyclic nucleotide phosphodiesterase (PDE4) inhibitor originated by Chiesi Farmaceutici with IC50 value of 0.026 ± 0.006 nM. CHF6001 inhibited PDE4 isoforms A to D with equal potency, showed an elevated ratio of high-affinity rolipram binding site versus low-affinity rolipram binding site and displayed >20,000-fold selectivity versus PDE4 compared with a panel of PDEs. In May 2016, Chiesi completed a phase I trial in Chronic Obstructive Pulmonary Disease (In volunteers) in United Kingdom (Inhalation). In Oct 2016, Phase-II clinical trials in Chronic obstructive pulmonary disease (Adjunctive treatment) in Hungary (Inhalation) was on-going. Uses: Allergic asthma; chronic obstructive pulmonary disease. Synonyms: CHF-6001; CHF 6001; CHF6001. UNII-0984EU6E2F; 0984EU6E2F; CHEMBL3113974; SCHEMBL12096092; CHF6001; VCFBPAOSTLMYIV-SANMLTNESA-N;[(1S)-1-[3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl]-2-(3,5-dichloro-1-oxidopyridin-1-ium-4-yl)ethyl] 3-(cyclopropylmethoxy)-4-(methanesulfonamido)benzoate. Grades: 98%. CAS No. 1239278-59-1. Molecular formula: C30H30Cl2F2N2O8S. Mole weight: 687.53. | |
| CHF-6162 | CHF-6162 is an agonist of glucocorticoid receptor (GR) (IC50 = 0.24nM), which shows greater potency than fluticasone and budesonide in a radioligand binding assay. Uses: The potential teatment of airway inflammation. Synonyms: CHF-6162; CHF 6162; CHF6162. | |
| Chidamide | Chidamide, also known as CS055 and HBI-8000, is an orally bioavailable benzamide type inhibitor of histone deacetylase (HDAC) isoenzymes 1, 2, 3 and 10, with potential antineoplastic activity. Chidamide selectively binds to and inhibits HDAC leading to an increase of acetylation levels of histone protein H3. This agent also inhibits the expression of signaling kinases in the PI3K/Akt and MAPK/Ras signaling pathways and may result in cell cycle arrest and the induction of tumor cell apoptosis. This may inhibit tumor cell proliferation in susceptible tumor cells. HDACs, a class of enzymes that deacetylate chromatin histone proteins, are upregulated in many tumor types and play key roles in gene expression. Compared to some other benzamide type HDAC inhibitors, chidamide is more stable, more resistant to degradation and has a longer half-life. Synonyms: CS055; CS-055; CS 055; HBI-8000; HBI 8000; HBI8000; N-(2-amino-5-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propen-1-yl]amino]methyl]-benzamide. CAS No. 743420-02-2. Molecular formula: C22H19FN4O2. Mole weight: 390.418. | |
| Chi Lob 7/4 | An IgG1 chimeric monoclonal antibody agonist of CD40 with potential immunostimulatory and antineoplastic activities. | |
| CHIR-124 | CHIR-124 is a quinolone-based small molecule Chk1 inhibitor, that is structurally unrelated to other known inhibitors of Chk1. It potently and selectively inhibits Chk1 in vitro (IC(50) = 0.0003 micromol/L). CHIR-124 interacts synergistically with topoisomerase poisons (e.g., camptothecin or SN-38) in causing growth inhibition in several p53-mutant solid tumor cell lines as determined by isobologram or response surface analysis. CHIR-124 is a novel and potent Chk1 inhibitor with promising antitumor activities when used in combination with topoisomerase I poisons. Synonyms: CHIR-124; CHIR 124; CHIR124. Grades: 0.98. CAS No. 405168-58-3. Molecular formula: C23H22ClN5O. Mole weight: 419.913. | |
| CHIR 2279 | CHIR 2279, an isoquinolin derivative, was once studied against hypertension as an α1 adrenergic receptor antagonist. Synonyms: Chir 2279; Chir2279; Chir 2279; (N-(2-(4-Hydroxyphenyl)ethyl)glycyl)-(N-(4-biphenylyl)glycyl)-N-(2-phenylethyl)glycinamide. Grades: 98%. CAS No. 158198-45-9. Molecular formula: C34H36N4O4. Mole weight: 564.674. | |
| CHIR-29498 | CHIR-29498 is a peptoid antibacterial agent. Synonyms: 2-[[(1R,4aS,10aR)-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthren-1-yl]methylamino]-N-(2-aminoethyl)-N-[2-[(2-amino-2-oxoethyl)-(1,2,3,4-tetrahydronaphthalen-1-yl)amino]-2-oxoethyl]acetamide ; CHIR-29498; CHIR 29498; CHIR29498; UNII-43I7U24XMF. Grades: >98%. CAS No. 236102-25-3. Molecular formula: C38H55N5O3. Mole weight: 629.88. | |
| CHIR 4531 | CHIR 4531, an oligopeptides compound, has been found to be an opioid mu receptor agonist and was once studied in pain therapy. Synonyms: Chir 4531; Chir4531; Chir-4531; AC1L322L; DTXSID90166381; (N-(2,2-Diphenylethyl)glycyl)-(N-(3,4-(methylenedioxy)benzyl)glycyl)-N-(2-(4-hydroxyphenyl)ethyl)glycinamide; AM017371. Grades: 98%. CAS No. 158198-48-2. Molecular formula: C36H38N4O6. Mole weight: 622.72. | |
| CHIR-98023 | CHIR-98023 is a glycogen synthase kinase 3 inhibitor developed for the treatment of Type 2 diabetes mellitus. Synonyms: N'-[4-(2,4-dichlorophenyl)-5-(1H-imidazol-2-yl)pyrimidin-2-yl]-N-(5-nitropyridin-2-yl)ethane-1,2-diamine; CHIR-98023; CHIR98023; CHIR 98023; CT-98023; UNII-CMQ1L0E91Y; CHIR-837. Grades: >98%. CAS No. 252916-76-0. Molecular formula: C20H16Cl2N8O2. Mole weight: 471.3. | |
| CHIR 99021 dihydrochloride | CHIR 99021 is a potent glycogen synthase kinase GSK-3 inhibitor. Synonyms: CHIR-99021 dihydrochloride; CHIR99021 dihydrochloride; CT-99021 dihydrochloride; CT 99021 dihydrochloride; CT99021 dihydrochloride; GSK-3 Inhibitor XVI dihydrochloride; 6-[2-[[4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)pyrimidin-2-yl]amino]ethylamino]pyridine-3-carbonitrile dihydrochloride. Grades: 99%. CAS No. 2109414-84-6. Molecular formula: C22H18Cl2N8.2HCl. Mole weight: 538.26. | |
| CHIR99021 HCl | CHIR99021, also known as CT99021, is a GSK-3α/β inhibitor (IC50= 10 nM/6.7 nM) with antiproliferative activity in vitro and in vivo. CHIR-99021 has also been shown to induce the reprogramming of murine and human somatic cells into stem cells. Synonyms: 6-((2-((4-(2,4-dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)amino)nicotinonitrile hydrochloride; CHIR99021 HCl; CHIR99021 hydrochloride; CHIR99021; CHIR-99021; CHIR 99021; CT99021; CT-99021; CT 99021. CAS No. 1797989-42-4. Molecular formula: C22H19Cl3N8. Mole weight: 501.8. | |
| CHIR 99021 trihydrochloride | CHIR 99021 is a highly selective GSK-3 inhibitor. CHIR 99021 is used in the treatment of parkinsonism. Uses: The treatment of parkinsonism. Synonyms: CHIR-99021 trihydrochloride; CHIR 99021 trihydrochloride; CHIR99021 trihydrochloride; 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile trihydrochloride. Grades: ≥98% by HPLC. CAS No. 1782235-14-6. Molecular formula: C22H18Cl2N8.3HCl. Mole weight: 574.72. | |
| Chk2 Inhibitor | Chk2 inhibitor is an inhibitor of checkpoint kinase 2 (Chk2; IC50 = 13.5 nM). Chk2 inhibitor enhances survival of 184B5, but not MDA-MB-231, cells following ionizing radiation and inhibits cell cycle arrest at the G2 stage induced by ionizing radiation in 184B5 cells. It also inhibits the production of IL-2 in Jurkat cells, the production of TNF-α in LPS-stimulated THP-1 cells and the growth of CEM leukemia T cells. Synonyms: SC-203885; (5Z)-5-(2-amino-1,5-dihydro-5-oxo-4H-imidazol-4-ylidene)-3,4,5,10-tetrahydro-azepino[3,4-b]indol-1(2H)-one; Hymenialdisine Analogue 1. CAS No. 724708-21-8. Molecular formula: C15H13N5O2. Mole weight: 295.3. | |
| Chlorcyclizine | Chlorcyclizine is a first-generation Histamine Receptor antagonist of the phenylpiperazine class. It can be used primarily to treat allergy symptoms such as rhinitis, urticaria, and pruritus, and may also be used as an antiemetic. Chlorcyclizine also has some anticholinergic, antiserotonergic, and local anesthetic properties. It also has been studied as a potential treatment for hepatitis C. Uses: Allergy symptoms. Synonyms: 1-[(4-Chlorophenyl)(phenyl)methyl]-4-methylpiperazine, 1-[(4-Chlorophenyl)phenylmethyl]-4-methyl-piperazine; 1620-21-9 (HCl salt); Di-Paralene; Mantadil; Pruresidine; Trihistan. Grades: 98%. CAS No. 82-93-9. Molecular formula: C18H21ClN2. Mole weight: 300.83. | |
| Chlorcyclizine hydrochloride | Chlorcyclizine is a phenylpiperazine that acts as a histamine H1 receptor antagonist (Ki = 9 nM). It is believed to be effective against hepatitis C virus (HCV; EC50 = 44 nM in vitro), targeting viral entry into host cells. Chlorcyclizine showed a synergistic effect with other hepatitis C drugs such as ribavirin, interferon, telaprevir, boceprevir, sofosbuvir, daclatasvir, and cyclosporin A. Synonyms: NSC 169496; Chlorcyclizine HCl; 1-[(4-chlorophenyl)phenylmethyl]-4-methyl-piperazine monohydrochloride. Grades: ≥98%. CAS No. 14362-31-3. Molecular formula: C18H21ClN2·HCl. Mole weight: 337.3. | |
| Chlorcyclizine hydrochloride (1:x) | The hydrochloride salt form of Chlorcyclizine which could be used as an antihistamine agent and is also found to have anticholinergic effect at some extent. Synonyms: Eramide; Chlorcyclizine HCl; Histantin; Perazil; Di-Paralene. CAS No. 1620-21-9. Molecular formula: C18H21ClN2.xHCl. Mole weight: 300.831 (free base). | |
| Chlorisondamine diiodide | Chlorisondamine diiodide is an exceptionally long-lasting and irreversible nicotinic acetylcholine receptor antagonist with IC50 value of 1.6 mM. It blocks central nicotinic responses and can persist for several weeks. It is used as an intracranial injection to study the analysis and localization of small drug molecules in rat brain tissue. Synonyms: 3-[[4-(Chlorophenyl)piperazin-1-yl]methyl-1H-pyrrolo[2,3-b]pyridine diiodide; 4,5,6,7-Tetrachloro-2,3-dihydro-2-methyl-2-[2-(trimethylammonio)ethyl]-2H-isoindolium diiodide. Grades: ≥99% by HPLC. CAS No. 96750-66-2. Molecular formula: C14H20Cl4I2N2. Mole weight: 611.95. | |
| Chlormethiazole hydrochloride | Chlormethiazole hydrochloride is the hydrochloride salt of chlormethiazole, which is a GABAA agonist. It is a useful research chemical and is used in the study of effects of thiazole methiodide and hydrochloride fractions of thiamine upon the neuromuscular system. It is neuroprotective in a number of animal models and is used as a sedative and anticonvulsant. It prevents the degeneration of serotonergic nerve terminals induced by MDMA. Synonyms: 4-methyl-5-(β-chloroethyl)thiazole hydrochloride; 5-(2-Chloroethyl)-4-methylthiazole hydrochloride; Somnevrin hydrochloride. Grades: ≥99% by HPLC. CAS No. 6001-74-7. Molecular formula: C6H9Cl2NS. Mole weight: 198.11. | |
| Chloropyramine hydrochloride | Chloropyramine hydrochloride. Synonyms: Halopyramine Hydrochloride; N-(β-Dimethylaminoethyl)-N-(p-chlorobenzyl)-α-aminopyridine Hydrochloride; NSC 409949; Sinopen Hydrochloride; Suprastin Hydrochloride; Alergosan; Allergan S Hydrochloride; Chlorpyramine Hydrochloride; Chloropyribenzamine Hydrochloride; 2-[(p-Chlorobenzyl)[2-(dimethylamino)ethyl]amino]-pyridine Monohydrochloride; N-[(4-Chlorophenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl-1,2-ethanediamine Monohydrochloride; N1-[(4-Chlorophenyl)methyl]-N2,N2-dimethyl-N1-2-pyridinyl-1,2-ethanediamine Hydrochloride. CAS No. 6170-42-9. Molecular formula: C16H20ClN3.HCl. Mole weight: 326.26. | |
| Chloroquine | An antimalarial agent. Synonyms: Aralen; Chlorochin; Chloraquine. Grades: 99.98%. CAS No. 54-05-7. Molecular formula: C18H26ClN3. Mole weight: 319.87. | |
| Chlorotrianisene | Chlorotrianisene is a powerful synthetic, non-steroidal estrogenic compound which is metabolized by liver microsomal enzymes primarily to the mono-O-demethylated derivative. It binds to the estrogen receptor on various estrogen receptor bearing cells. It was used for the treatment of menopause, deficiencies in ovary function, and prostate cancer. It belongs triphenylethylene group. It was derived from estrobin (DBE) and is a relatively weak estrogen. It is a selective estrogen receptor modulator (SERM), with predominantly estrogenic but also antiestrogenic effects, and was arguably the first SERM to ever be introduced. It has been listed. Uses: Chlorotrianisene was used for the treatment of menopause, deficiencies in ovary function, and prostate cancer. Synonyms: 1, 1', 1''-(1-Chloro-1-ethenyl-2-ylidene)-tris(4-methoxybenzene); 1-[2-Chloro-1, 2-bis(4-methoxyphenyl)vinyl]-4-methoxybenzene; Chlortrianisestrol; Chlortrianizen; Khlortrianizen; Hormonisene; Anisene; Metace; Rianil; Tace; 1-[1-Chloro-2, 2-bis(4-methoxyphenyl)ethenyl]; Chlorotrianisene; Chlortrianisestrol; Chlortrianizen; Chlorotrianisine; Chlorestrolo; Chlorotrianizen; Khlortrianizen; Clorestrolo; Clorotrisin; Hormonisene; Anisene; Metace; Rianil; Tace. Grades: 95%. CAS No. 569-57-3. Molecular formula: C23H21ClO3. Mole weight: 380.87. | |
| Chlorphenoxamine | Chlorphenoxamine is an analog of diphenhydramine. It has antimuscarinic and antihistaminic properties. It has been used as an antipruritic and antiparkinsonian agent. Uses: Chlorphenoxamine has been used as an antipruritic and antiparkinsonian agent. Synonyms: 2-(1-(p-Chlorophenyl)-1-phenylethoxy)-N,N-dimethylethylamine;2-[1-(4-Chlorophenyl)-1-phenylethoxy]-N,N-dimethylethanamine;beta-Dimethylamino-aethyl-(p-chlor-alpha-methylbenzhydryl)-aether;Ethylamine, 2-[1-(p-chlorophenyl)-1-phenylethoxy]-N,N-dimethyl-;p-Chlor-alpha-methyl-diphenhydramin;N-(2-(1-p-chlorophenyl-1-phenylethoxy)ethyl)dimethylamine;1-(4-Chlorophenyl)-1-[2-(dimethylamino)ethoxy]-1-phenylethane;Contristamine; Systral. Grades: >98%. CAS No. 77-38-3. Molecular formula: C18H22ClNO. Mole weight: 303.84. | |
| Chlorpromazine | Chlorpromazine is a low-potency typical antipsychotic agent that is used to treat psychotic disorders. Chlorpromazine exerts its antipsychotic effect by blocking postsynaptic dopamine receptors in cortical and limbic areas of the brain, thereby preventing the excess of dopamine in the brain. This leads to a reduction in psychotic symptoms, such as hallucinations and delusions. Synonyms: Thorazine; Largactil; Contomin; 3-(2-chlorophenothiazin-10-yl)-N,N-dimethylpropan-1-amine. CAS No. 50-53-3. Molecular formula: C17H19ClN2S. Mole weight: 318.86. | |
| Chlorprothixene | Chlorprothixene has strong binding affinities to dopamine and histamine receptors, such as D1, D2, D3, D5, H1, 5-HT2, 5-HT6 and 5-HT7, with Ki of 18 nM, 2.96 nM, 4.56 nM, 9 nM, 3.75 nM, 9.4 nM, 3 nM and 5.6 nM, respectively. Uses: Antipsychotic agents; dopamine antagonists. Grades: >98%. CAS No. 113-59-7. Molecular formula: C18H18ClNS. Mole weight: 315.86. | |
| Chlorprothixene hydrochloride | Chlorprothixene hydrochloride is the hydrochloride salt form of chlorprothixene, a typical thioxanthine antipsychotic that functions by antagonizing dopamine D2 receptors. It can block a subset of GABAA receptors in rat cortex that is also blocked by clozapine. It exerts strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrenergic receptors. It has also been shown to be effective against P. falciparum growth with an EC50 value of 1.7 μM. Synonyms: cis-Chlorprothixene; NSC 169899; Minithixen hydrochloride; Truxal hydrochloride; NSC 56379; NSC 78193; (3Z)-3-(2-chlorothioxanthen-9-ylidene)-N,N-dimethylpropan-1-amine;hydrochloride. Grades: ≥98%. CAS No. 6469-93-8. Molecular formula: C18H18ClNS·HCl. Mole weight: 352.3. | |
| chlortetracycline hydrochloride (1:x) | Chlortetracycline HCl is the first identified tetracycline antibiotic. Uses: Anti-bacterial agents. Synonyms: Chlortetracycline HCl; (4aS,5aS,6S,12aR)-7-chloro-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide hydrochloride. Grades: >98%. CAS No. 3671-8-7. Molecular formula: C22H23ClN2O8.xHCl. Mole weight: 478.886 (free base). | |
| Chlorthal-dimethyl | Chlorthal-dimethyl, also called as Dacthal, it is metabolized in animals to monomethyl ester and chlorthal which are eliminated in urine and used as a pesticide intermediate. Synonyms: dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate Dacthal DCPA dimethyl 2,3,5,6-tetrachloro-terephthalate dimethyl 2,3,5,6-tetrachloroterephthalate. CAS No. 1861-32-1. Molecular formula: C10H6Cl4O4. Mole weight: 331.96. | |
| CHM 1 | CHM 1 is an apoptosis inducer with potent antitumor activity in human hepatocellular carcinoma. It inhibits tubulin polymerization in vitro and in vivo, and results in cell cycle arrest at G2/M phase by activating Cdc2 kinase activity. CHM 1 also exhibits vascular targeting activity via upregulation of p53 and induction of death receptor (DR5)-mediated apoptosis in HUVEC cells. Uses: Antitumor agent. Synonyms: CHM-1; CHM 1; CHM1; NSC 656158; NSC-656158; NSC656158; 6-(2-Fluorophenyl)-1,3-dioxolo[4,5-g]quinolin-8(5H)-one. Grades: ≥99% by HPLC. CAS No. 154554-41-3. Molecular formula: C16H10FNO3. Mole weight: 283.25. | |
| CHMFL-ABL-053 | CHMFL-ABL-053 is a potent and orally available inhibitor of BCR-ABL (IC50 = 70 nM) without inhibitory activity against c-KIT kinase that is a common target of BCR-ABL inhibitors currently used. A pharmacokinetic study revealed that it had 4.3h of half-life and 24% bioavailability in rats. It is developed for the treatment of chronic myeloid leukemia (CML). Uses: The treatment of chronic myeloid leukemia (cml). Synonyms: CHMFL-ABL-053; CHMFL-ABL053; CHMFL-ABL 053. 2 - ((3-Amino-4-methylphenyl)amino) - N - (2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide. CAS No. 1808287-83-3. Molecular formula: C28H26F3N7O2. Mole weight: 549.56. | |
| CHMFL-FLT3-122 | CHMFL-FLT3-122 is a potent and selective FLT3 inhibitor (IC50 = 40 nM) with >10-fold and 170-fold selectivity for FLT3 over BTK kinase and c-KIT kinase. It causes apoptosis via cell cycle arrest in G0/G1 phase in vitro. In MV4-11 cell inoculated xenograft model, it suppressed tumor growth. Uses: Antitumor agent. Synonyms: CHMFL-FLT3-122; CHMFL FLT3 122; CHMFLFLT3122; 1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-(dimethylamino)-ethanone. CAS No. 1839150-56-9. Molecular formula: C26H29N7O2. Mole weight: 471.55. | |
| CHPG | CHPG is a selective metabotropic glutamate 5 (mGlu5) receptor agonist, and it is inactive in CHO cells. CHPG potentiates NMDA-induced depolarizations in rat hippocampal slices, and promotes proliferation of human embryonic cortical NSCs with activation of the MAPKs signaling pathway. Uses: Excitatory amino acid agonists. Synonyms: (RS)-2-Chloro-5-hydroxyphenylglycine; 2-chloro-5-hydroxyphenylglycine; 2-Amino-2-(2-chloro-5-hydroxyphenyl)acetic acid. Grades: ≥99% by HPLC. CAS No. 170846-74-9. Molecular formula: C8H8NO3Cl. Mole weight: 201.61. | |
| CHPG Sodium salt | The sodium salt of CHPG, which is the selective metabotropic glutamate 5 (mGlu5) receptor agonist. Synonyms: (RS)-2-Chloro-5-hydroxyphenylglycine sodium salt. Grades: ≥99% by HPLC. CAS No. 1303993-73-8. Molecular formula: C8H7ClNNaO3. Mole weight: 223.59. | |
| Chroman 1 | Chroman 1, a chroman-based compound, is an effective ROCK II inhibitor which could probably influence the cell motility involved in sorts of disorders. Uses: Chroman 1is an effective rock ii inhibitor which could probably influence the cell motility involved in sorts of disorders. Synonyms: Chroman 1; Chroman-1; Chroman1. (3S)-N-[2-[2-(dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)phenyl]-6-methoxy-3,4-dihydro-2H-chromene-3-carboxamide;chroman1;1273579-40-0;CHEMBL3221807;3543AH;CS-0775; CS 0775; CS0775. Grades: 95%. CAS No. 1273579-40-0. Molecular formula: C24H28N4O4. Mole weight: 436.50. | |
| Chromanol 293B | Chromanol 293B is a specific slow delayed rectifier K+ current (IKs) blocker with an IC50 value of 6.89 μM in xenopus oocytes expressing rat. It shows no activity at rat Kv1.1 or Kir2.1 channels at a concentration of 30 μM. It inhibits cystic fibrosis transmembrane conductance regulator (CTFR) Cl- currents (ICTFR) with an IC50 value of 19 μM in xenopus oocytes expressing human CTFR. It increases the extent and rate of IKs in guinea pig ventricular cells in a dose-dependent manner. It is a useful research chemical. Uses: Potassium channel blockers. Synonyms: rel-N-[(3R,4S)-6-cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-methyl-ethanesulfonamide; rel-N-[(3R,4S)-6-Cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-methylethanesulfonamide; trans-N-[6-Cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-methyl-ethanesulfonamide. Grades: ≥99% by HPLC. CAS No. 163163-23-3. Molecular formula: C15H20N2O4S. Mole weight: 324.39. | |
| CHS-828 | CHS-828 is a synthetic guanidine-based small anticancer molecule. CHS 828 was found to exert potent cytotoxic effects in human breast and lung cancer cell lines, with lesser effects on normal fibroblasts and endothelial cells. In nude mice bearing human tumor xenografts, CHS 828, at doses from 20 to 50 mg/kg/day p.o., inhibited the growth of MCF-7 breast cancer tumors and caused regression of NYH small cell lung cancer tumors. Oral administration of CHS 828 once weekly improved efficacy without increasing toxicity. CHS 828 was found to compare favorably with established chemotherapeutic agents such as cyclophosphamide, etoposide, methotrexate, and paclitaxel. In mice with NYH tumors, long-term survival (>6 months) was observed after treatment with CHS 828 was stopped. CHS 828 is an effective new antitumor agent, with a potentially new mechanism of action. CHS-828 appeared to kill cancer cells by depleting NAD. CHS 828 is presently being tested in Phase I clinical trials in collaboration with the European Organization for Research and Treatment of Cancer. Synonyms: CHS 828; CHS828; CHS-828; GMX-1778; GMX1778; GMX 1778. CAS No. 200484-11-3. Molecular formula: C19H22ClN5O. Mole weight: 371.869. | |
| CI 1002 | CI 1002, an azepinoquinazoline derivative, has been found to be an acetylcholinesterase inhibitor that could probably be effective against cognitive dysfunction in Alzheimer's disease. It has already been discontinued by Pfizer. Synonyms: UNII-7U374ZW3YB; CI-1002; CI 1002; CI1002; 1,3-Dichloro-6,7,8,9,10,12-hexahydroazepino(2,1-b)quinazoline; 1,3-dichloro-6,7,8,9,10,12-hexahydroazepino[2,1-b]quinazoline; PD-142676; PD 142676; PD142676. Grades: 98%. CAS No. 149028-28-4. Molecular formula: C13H14Cl2N2. Mole weight: 269.17. | |
| CI-1002 hydrochloride | The hydrochloride salt form of CI 1002, an azepinoquinazoline derivative, has been found to be an acetylcholinesterase inhibitor that could probably be effective against cognitive dysfunction in Alzheimer's disease. Synonyms: CI-1002 hydrochloride; CI 1002 hydrochloride; CI1002 hydrochloride; UNII-I77CZ53Y9M; PharmaGSID_47259; 149062-75-9; 1,3-Dichloro-6,7,8,9,10,12-hexahydroazepino(2,1-b)quinazoline hydrochloride; CI-1002 hydrochloride; 1,3-dichloro-6,7,8,9,10,12-hexahydroazepino[2,1-b]quinazoline hydrochloride. Grades: 98%. CAS No. 149062-75-9. Molecular formula: C13H15Cl3N2. Mole weight: 305.63. | |
| CI-1018 | CI-1018 is a selective type 4 phosphodiesterase inhibitor associated with vasculitis. CI-1018 has been in development to suppress inflammation. Synonyms: 4-Pyridinecarboxamide, N-(3,4,6,7-tetrahydro-9-methyl-4-oxo-1-phenylpyrrolo(3,2,1-jk)(1,4)benzodiazepin-3-yl)-; CI-1018; CI-1018; CI-1018; UNII-05127JZ9KQ. Grades: >98%. CAS No. 245329-99-1. Molecular formula: C24H20N4O2. Mole weight: 396.44. | |
| CI 1020 | CI 1020 has been found to be a novel endothelin-A receptor antagonist and could be used as an antihypertensive agent. Synonyms: CI 1020; CI1020; CI-1020; 3-(1,3-Benzodioxol-5-yl)-5-hydroxy-5-(4-methoxyphenyl)-4-[(3,4,5-trimethoxyphenyl)methyl]-2(5H)-furanone. Grades: ≥98% by HPLC. CAS No. 162256-50-0. Molecular formula: C28H26O9. Mole weight: 506.50. | |
| CI-1040 | CI-1040 is a MEK inhibitor, which demonstrated in vivo activity in preclinical animal models and subsequently became the first MEK inhibitor to enter clinical trial. CI-1040 suffered however from poor exposure due to its poor solubility and rapid clearance, and as a result, development of the compound was terminated. Synonyms: CI1040; CI-1040; CI 1040; PD184352; PD 184352; PD-184352. CAS No. 212631-79-3. Molecular formula: C17H14ClF2IN2O2. Mole weight: 478.662. | |
| CI-898 hydrochloride | CI-898 is a lipophilic antifolate inhibitor of dihydrofolate reductase (DHFR). The presence of the cofactor NADPH enhances bind of CI-898 and DHFR. CI-898 inhibits growth and halts the cell cycle at the G1/S phase in L1210 mouse lymphocytic leukemia cells and is active against methotrexate-resistant cancer cell lines. It also inhibits the growth of S. faecalis and S. aureus when used at concentrations less than 0.25 μg/ml. It also enhances the activity of doxorubicin, cyclophosphamide, and 6-thioguanine in mice with advanced stage P338 leukemia. Synonyms: Trimetrexate; CI 898 trihydrochloride; Trimetrexate trihydrochloride; TMTX. Grades: ≥98%. CAS No. 1658520-97-8. Molecular formula: C19H23N5O3·3HCl. Mole weight: 478.80. | |
| CI 951 | CI 951 is a dihydronaphthyridine Ca2+ channel antagonist and it may be applicated for the treatment of focal cerebral ischemia. CI 951 has potential as a cerebral vasodilator. Uses: Focal cerebral ischemia. Synonyms: CI 951; CI-951; CI951. 1,6-Naphthyridine-3-carboxylic acid, 1,4-dihydro-2-methyl-5-(1-methylethoxy)-4-(2-(trifluoromethyl)phenyl)-, ethyl ester. Grades: 98%. CAS No. 126661-07-2. Molecular formula: C22H23F3N2O3. Mole weight: 420.42. | |
| CI966 | CI966 is a highly potent and selective blocker of the GABA transporter 1 (GAT-1) with IC50 value of 0.26 μM acting as a central nervous system depressant. It has potential as a potential anxiolytic, anticonvulsant and neuroprotective therapeutic but was discontinued during clinical development due to the incidence of severe adverse effects at higher doses and hence was never marketed. In a phase I human clinical trial it was developed for the treatment of epilepsy. Uses: Ci966 it has potential as a potential anxiolytic, anticonvulsant and neuroprotective therapeutic. it was developed for the treatment of epilepsy. Synonyms: CI-966; CI 966; CI966; CHEMBL77287; CHEMBL542207; 1- (2- (Bis (4- (trifluoromethyl) phenyl) methox) ethyl) -1, 2, 5, 6-tetrahydro-3-pyrdinecarboxylic acid. Grades: >98%. CAS No. 110283-79-9. Molecular formula: C23H21F6NO3. Mole weight: 473.41. | |
| CI 966 hydrochloride | The hydrochloride salt form of CI 966, which is an inhibitor of the GABA transporter and could be used as anticonvulsive as well as neuroprotective agent. Synonyms: CI 966 hydrochloride; CI966 hydrochloride; CI-966 hydrochloride; 1-[2-[bis[4- (Trifluoromethyl) phenyl]methoxy]ethyl]-1, 2, 5, 6-tetrahydropyridine-3-carboxylic acid hydrochloride. Grades: ≥98% by HPLC. CAS No. 110283-66-4. Molecular formula: C23H21F6NO3.HCl. Mole weight: 509.87. | |
| CI 969 | This active molecular is a muscarinic agonist agent. Synonyms: CI 969; CI969; CI-969; (Z)-1-(1-methyl-1,2,5,6-tetrahydropyridin-3-yl)ethanone O-acetyl oxime hydrochloride. Grades: 98%. CAS No. 113590-49-1. Molecular formula: C10H17ClN2O2. Mole weight: 232.71. | |
| CI 988 | CI 988 has been found to be a CCK-2 receptor antagonist and could exhibit anxiolytic activity. Uses: Anti-anxiety agents. Synonyms: CI 988; CI988; CI-988; PD 134308, PD-134,308, PD-134308; 4-[[(1R)-2-[[(2R)-3-(1H-indol-3-yl)-2-methyl-1-oxo-2-[[(tricyclo[3.3.1.13,7]dec-2-yloxy)carbonyl]amino]propyl]amino]-1-phenylethyl]amino]-4-oxobutanoic acid. Grades: ≥99% by HPLC. CAS No. 130332-27-3. Molecular formula: C35H42N4O6. Mole weight: 614.73. | |
| Cibacron Blue | Cibacron Blue is a renowned dye extensively employed in the biomedical sector exhibiting remarkable utility in the researchs of affinity chromatography and protein purification. Its distinct affinity towards biological entities, namely enzymes, proteins and biomolecules, renders it an invaluable tool in the research of a wide range of ailments encompassing cancer, diabetes and infectious diseases. Synonyms: Cibacron blue 3GA; 1-amino-4-[4-[[4-chloro-6-(2-sulfoanilino)-1,3,5-triazin-2-yl]amino]-3-sulfoanilino]-9,10-dioxoanthracene-2-sulfonic acid. CAS No. 84166-13-2. Molecular formula: C29H20ClN7O11S3. Mole weight: 774.16. | |
| CID-2858522 | CID-2858522 selectively inhibits the NF-κB pathway induced by PKC, operating downstream of PKC but upstream of IKKbeta, without inhibiting other NF-kappaB activation pathways. Synonyms: CID2858522; CID-2858522; CID 2858522; ML029; ML-029; ML 029. Grades: >98%. CAS No. 758679-97-9. Molecular formula: C28H39N3O3. Mole weight: 465.63. | |
| Ciglitazone | Ciglitazone is a selective agonist at peroxisome proliferator-activated receptor γ (PPARγ) with an EC50 value of 3 μM in vitro. It is at least 33-fold selective over PPARα and &delta. It shows antihyperglycemic activity in genetically obese C57 B1/6 ob/ob mice and is used as an antihyperglycemic agent. Uses: Hypoglycemic agents. Synonyms: ADD 3878; ADD-3878; ADD3878; Ciglitazona; U 63287; U-63287; U63287; ADD 3878; ADD-3878; ADD3878; (+/-) -5-[4- (1-methylcyclohexylmethoxy) benzyl]thiazolidine-2, 4-dione; ADD-3878; 5-[[4-[ (1-Methylcyclohexyl) methoxy]phenyl]methyl]-2, 4-thiazolidinedione. Grades: ≥99% by HPLC. CAS No. 74772-77-3. Molecular formula: C18H23NO3S. Mole weight: 333.44. | |
| Cilazapril Monohydrate | Cilazapril is a angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and congestive heart failure. Uses: Angiotensin-converting enzyme inhibitors. Synonyms: CILAZAPRIL MONOHYDRATE;6H-Pyridazino(1,2-a)(1,2)diazepine-1-carboxylic acid, 9-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)octahydro-10-oxo-, monohydrate, (1S-(1alpha,9alpha(R*)))-; 6H-Pyridazino(1,2-a)(1,2)diazepine-1-carboxylic acid, octahydro-9-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-10-oxo-, hydrate, (1S-(1-alpha,9-alpha(R*)))-; MS-27800; D01069; Q27252108; (1S,9S)-9-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}-10-oxooctahydro-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid hydrate; (1S,9S)-9-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}-10-oxooctahydro-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid--water (1/1); 6H-PYRIDAZINO(1,2-A)(1,2)DIAZEPINE-1-CARBOXYLIC ACID, 9-((1-(ETHOXYCARBONYL)-3-PHENYLPROPYL)AMINO)OCTAHYDRO-10-OXO-, MONOHYDRATE, (1S-(1.ALPHA.,9.ALPHA.A(R*)))-. Grades: >98%. CAS No. 92077-78-6. Molecular formula: C22H33N3O6. Mole weight: 435.51. | |
| Cilobradine hydrochloride | Cilobradine hydrochloride, also called as DK-AH 269, a benzazepinone derivative, is an HCN Channel blocker that might be beneficial in the treatment of cardiovascular diseases, e.g. ischemia. Synonyms: 3-[[(3S)-1-[2-(3,4-dimethoxyphenyl)ethyl]piperidin-3-yl]methyl]-7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one;hydrochloride 1,3,4,5-tetrahydro-7,8-dimethoxy-3-((1-(2-(3,4-dimethoxyphenyl)ethyl)-3-piperidinyl)methyl)-2H-3-benzazepin-2-one hydrochloride D. CAS No. 186097-54-1. Molecular formula: C28H39ClN2O5. Mole weight: 519.07. | |
| Cilostamide | Cilostamide is a selective and specific inhibitor of type III phosphodiesterase (PDE3). It shows moderate selectivity for PDE3A isozyme and PDE3B. It increases intracellular cAMP and inhibits ADP-induced platelet aggregation. It has an antithrombotic effect. Uses: Phosphodiesterase inhibitors. Synonyms: Cilostamide; OPC 3689; OPC-3689; OPC3689; N-Cyclohexyl-N-methyl-4-(1,2-dihydro-2-oxo-6-quinolyloxy)butyramide; 6-[3-(N-Cyclohexyl-N-methylcarbamoyl)propoxy]quinolin-2[1H]-one. CAS No. 68550-75-4. Molecular formula: C20H26N2O3. Mole weight: 342.44. | |
| Ciluprevir | Ciluprevir is used experimentally in the treatment of hepatitis C. It is manufactured by Boehringer Ingelheim Pharma GmbH & Co. kg and developed under the research code of BILN-2061. It is targeted against NS2-3 protease. Synonyms: BILN 2061; BILN-2061; BILN2061; BILN-2061ZW; BILN2061ZW; BILN 2061ZW; Ciluprevir. Grades: >98%. CAS No. 300832-84-2. Molecular formula: C40H50N6O8S. Mole weight: 774.93. | |
| CIM 0216 | CIM 0216 has been found to be a selective TRPM3 agonist and could stimulate the release of insulin from pancreatic islet cells. Synonyms: CIM-0216; CIM 0216; CIM0216; 3,4-Dihydro-N-(5-methyl-3-isoxazolyl)-α-phenyl-1(2H)-quinolineacetamide. Grades: ≥98% by HPLC. CAS No. 1031496-06-6. Molecular formula: C21H21N3O2. Mole weight: 347.41. | |
| Cimbuterol | Cimbuterol is a β-adrenergic agonist. Synonyms: 2-Amino-5-(2-tert-butylamino-1-hydroxyethyl)-benzonitrile. CAS No. 54239-39-3. Molecular formula: C13H19N3O. Mole weight: 233.315. | |
| Cinacalcet | Cinacalcet is the first calcimimetic drug approved by the United States Food and Drug Administration for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease. Synonyms: Sensipar, (R)-N-[-1-(1-naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine. Grades: 0.98. CAS No. 226256-56-0. Molecular formula: C22H22F3N. Mole weight: 357.41. | |
| Cinalukast | Cinalukast is a selective Leukotriene D4 receptor antagonist originated by Roche and IC 50 value is 6.4 nM. Cinalukast inhibits the actions of Leukotriene D4 at the CysLT1 receptor and it can prevent airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus. Treatment for Asthma was discontinued. Uses: Asthma. Synonyms: Ro 24-5913; UNII-5E1O433QAI; CHEMBL283754;4-[[3-[(1E)-2-(4-Cyclobutyl-2-thiazolyl)ethenyl]phenyl]amino]-2,2-diethyl-4-oxo-Butanoic Acid. Grades: 98 %. CAS No. 128312-51-6. Molecular formula: C23H28N2O3S. Mole weight: 412.55. | |
| Cinanserin hydrochloride | Cinanserin hydrochloride is the hydrochloride salt of cinanserin, which is a 5-HT2 antagonist and an inhibitor of GPVI-mediated cell activation. It also acts as an inhibitor of CRP-XL- and collagen-induced Ca2+ release and aggregation. It is also an inhibitor of 3C-like proteinase of severe acute respiratory syndrome coronavirus, and it strongly reduces virus replication in vitro. Uses: Serotonin antagonists. Synonyms: Cinanserin HCl; Cinanserin Hydrochloride; SQ-10643; SQ 10643; SQ10643; NSC-125717; NSC 125717; NSC125717; (E) -N-[2-[3- (Dimethylamino) propylsulfanyl]phenyl]-3-phenylprop-2-enamide hydrochloride; N-[2-[[3-(Dimethylamino)propyl]thio]phenyl]-3-phenyl-2-propenamide Hydrochloride; MAPTC; SQ 10643; 2'-[[3- (Dimethylamino) propyl]thio]cinnamanilide Hydrochloride. Grades: ≥99% by HPLC. CAS No. 54-84-2. Molecular formula: C20H25N2OSCl. Mole weight: 376.94. | |
| Cindunistat hydrochloride maleate | Cindunistat is a selective Nitric oxide synthase (iNOS) type II inhibitor. It is potentially useful in patients with symptomatic osteoarthritis of the knee. But in Feb 2012, Phase-II/III for Osteoarthritis was discontinued. Uses: Osteoarthritis. Synonyms: PHA-728669F; PHA 728669F; PHA728669F; SD-6010; SD 6010; SD6010 PF-00572986; PF00572986; PF 00572986; PF-572986; PF572986; PF 572986; PHA-84250; PHA84250; PHA 84250; SC-084250; SC 084250; SC084250; Cindunistat. cindunistat hydrochloride maleate;(R,Z)-2-amino-3-((2-((1-aminoethylidene)amino)ethyl)thio)-2-methylpropanoic acid compound with maleic acid (2:1) hydrochloride. Grades: 98%. CAS No. 753491-31-5. Molecular formula: C20H39ClN6O8S2. Mole weight: 591.15. | |
| Cinitapride hydrogen tartrate | Cinitapride hydrogen tartrate is a gastroprokinetic agent that acts as an agonist of the 5-HT1 and 5-HT4 receptors and as an antagonist of the 5-HT2 receptors. Synonyms: 4-amino-N-[1-(cyclohex-3-en-1-ylmethyl)piperidin-4-yl]-2-ethoxy-5-nitrobenzamide; (2R,3R)-2,3-dihydroxybutanedioic acid. CAS No. 1207859-16-2. Molecular formula: C25H36N4O10. Mole weight: 552.57. | |
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