BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Cinnabarinic acid | Cinnabarinic acid is a kynurenine pathway metabolite of tryptophan and is produced by the oxidation of 3-Hydroxyanthranilic acid. It is a metabotropic glutamate receptor (mGlu4R-specific) agonist. It activates mGlu4 receptors in transiently transfected HEK293 cells and is selective over all other mGlu subtypes. It decreases cAMP levels in native cultured cerebellar granule cells. It may be used in studies of the functions of components of the kynurenine metabolic pathway. It leads to loss of apoptosis and mitochondrial respiration. It induces apoptosis in thymocytes by the generation of reactive oxygen species. It also counteracts excitotoxic neuronal cell death induced by NMDA in mixed cultures of cortical cells. It has neuroprotective activity. Synonyms: 2-Amino-3-oxo-3H-phenoxazine-1,9-dicarboxylic acid. Grades: ≥98% by HPLC. CAS No. 606-59-7. Molecular formula: C14H8N2O6. Mole weight: 300.22. |  |
| Cinobufotalin | Cinobufotalin is one of the bufadienolides prepared from toad venom. It has anticancer activity. Uses: Analgesic, anti-inflammatory, antitumor, anesthesia. Synonyms: 14,15b-Epoxy-3b,5a,16b-trihydroxy-5b,20(22)-bufadienolide 16-acetate. Grades: >98%. CAS No. 1108-68-5. Molecular formula: C26H34O7. Mole weight: 458.54. | |
| Cinoxacin | Cinoxacin, a quinolone carboxylic acid derivative that structurally resembles ciprofloxacin, was an older synthetic antimicrobial to treat urinary tract infections. Uses: Topoisomerase ii inhibitors. Synonyms: 1-ethyl-4-oxo-[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid 64716, Compound Acid, Azolinic Azolinic Acid Cinobac Cinoxacin Clinoxacin Compound 64716. CAS No. 28657-80-9. Molecular formula: C12H10N2O5. Mole weight: 262.22. | |
| Cipargamin | NITD609 is a novel antimalarial drug candidate, with IC50 of appr 1 nM against P. falciparum. Synonyms: (3R,3'S)-5,7'-dichloro-6'-fluoro-3'-methylspiro[1H-indole-3,1'-2,3,4,9-tetrahydropyrido[3,4-b]indole]-2-one; cipargamin; NITD609, NITD 609, NITD-609, KAE609, KAE 609, KAE-609, GNF-609; GNF 609; GNF609; Cipargamin. CAS No. 1193314-23-6. Molecular formula: C19H14Cl2FN3O. Mole weight: 390.24. | |
| Ciproxifan | Ciproxifan is a highly potent and selective histamin H3-receptor antagonist with IC50 of 9.2 nM, with low apparent affinity at other receptor subtypes. Synonyms: FUB 359; FUB359; FUB-359. Grades: >98%. CAS No. 184025-18-1. Molecular formula: C16H18N2O2.C4H4O4. Mole weight: 386.4. | |
| Ciproxifan maleate | Ciproxifan maleate, also called as FUB-359 maleate, is a highly potent and strongly selective histamine H3 inverse agonist/antagonist (IC50 = 9.2 nM) which displays little affinity for other receptor subtypes. Synonyms: (Z)-but-2-enedioic acid;cyclopropyl-[4-[3-(1H-imidazol-5-yl)propoxy]phenyl]methanone Ciproxifan maleate Ciproxifan (maleate) FUB 359 maleate salt 184025-19-2 Cyclopropyl (4-[3-(1H-imidazol-4-yl)propyloxy]phenyl) ketone maleate salt ciproxifan?FUB359 FUB 3. CAS No. 184025-19-2. Molecular formula: C20H22N2O6. Mole weight: 386.40. | |
| CIQ | CIQ is a derivative of tetrahydroisoquinoline acts as subunit-selective potentiator of NMDA receptors containing the NR2C (EC50=2.7 μM) or NR2D (EC50=2.8 μM) subunit. Uses: A substituted tetrahydroisoquinoline. Synonyms: (3-chlorophenyl)-[6,7-dimethoxy-1-[(4-methoxyphenoxy)methyl]-3,4-dihydro-1H-isoquinolin-2-yl]methanone; (3-chlorophenyl)[3,4-dihydro-6,7-dimethoxy-1-[(4-methoxyphenoxy)methyl]-2(1H)-isoquinolinyl]-methanone. Grades: ≥98%. CAS No. 486427-17-2. Molecular formula: C26H26ClNO5. Mole weight: 467.94. | |
| Cirazoline hydrochloride | Cirazoline hydrochloride is the hydrochloride salt of cirazoline, which is a potent and selective α1-adrenergic receptor (α1-AR) agonist with Ki value of 120 nM for recombinant α1AR in CHO cell membranes. It is non-selective imidazoline binding site ligand and acts as a full agonist at α1A- and a partial agonist at α1B- and α1D-ARs in vitro. It decreases blood pressure when administered via microinjection to the nucleus reticularis lateralis (NRL) of anesthetized normotensive cats. It enhances spatial memory and reduces depressive- and anxiety-like behavior in mic. It also enhances performance in the variable delayed response task in aged rhesus monkeys at high doses of 1-10 μg/kg. It also impairs performance at lower doses of 0.01-1 μg/kg. It is also a particularly effective vasoconstricting agent. Synonyms: Cirazoline Hydrochloride; Cirazoline HCl; 2-[(2-Cyclopropylphenoxy)methyl]-4,5-dihydro-1H-imidazole Hydrochloride; LD-3098; LD3098; LD 3098. Grades: ≥99% by HPLC. CAS No. 40600-13-3. Molecular formula: C13H17N2OCl. Mole weight: 252.74. | |
| cis-ACCP | cis-ACCP is a reversible and competitive inhibitor of type IV collagen-specific MMP-2 and MMP-9. Synonyms: [(1R,2S)-2-aminocyclohexyl]carbamoylphosphonic acid; P-[[[(1R,2S)-2-aminocyclohexyl]amino]carbonyl]-phosphonic acid. Grades: ≥95%. CAS No. 777075-44-2. Molecular formula: C7H15N2O4P. Mole weight: 222.2. | |
| cis-ACPD | cis-ACPD has been found to be a potent NMDA receptor agonist as well as a mGluR agonist. Synonyms: (±)-1-Aminocyclopentane-cis-1,3-dicarboxylic acid. Grades: ≥98% by HPLC. CAS No. 477331-06-9. Molecular formula: C7H11NO4. Mole weight: 173.17. | |
| cis-Anethol | Cas No. 104-46-1. | |
| Cisapride hydrate | Cisapride, also called as R51619, is a serotonin 5-HT4 receptor agonist used as a gastroprokinetic agent. Cisapride stimulates gastrointestinal motility, probably by facilitating acetylcholine release at the myenteric plexus. Synonyms: 4-amino-5-chloro-N-[(3S,4R)-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-yl]-2-methoxybenzamide; hydrate; Cisapridemonohydrate; 260779-88-2; cis-4-Amino-5-chloro-N-[1-[3-(4-fluorophenoxy)propyl]-3-methoxy-4-piperidinyl]-2-methoxybenxamidemonohydrate; CISAPRIDEMONOHYDRATE; 81098-60-4 (Cisapride free base); 189888-25-3 (Cisapride tartrate); 260779-88-2 (Cisapride hydrate). Grades: ≥99%. CAS No. 260779-88-2. Molecular formula: C23H29N3O4ClFH2O. Mole weight: 483.96. | |
| cis-Diethylstilbestrol | The cis-isomer of diethylstilbestrol, a synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. Synonyms: CCRIS 9140; 4-[(1Z)-1-ethyl-2-(4-hydroxyphenyl)but-1-enyl]phenol; AI3-17297. CAS No. 22610-99-7. Molecular formula: C18H20O2. Mole weight: 268.35. | |
| cis-Flupenthixol hydrochloride | cis-Flupenthixol is a typical antipsychotic, a dopamine D2 receptor antagonist, and an inverse agonist at the serotonin (5-HT) receptor subtype 5-HT2A. In vivo, cis-flupenthixol reduces cocaine-induced locomotor activity and prevents development of conditioned place preferences for the immediate effects of intravenously administered cocaine without affecting development of conditioned place aversions in rats. It is also a neuroleptic agent related structurally to thiothixene. Uses: Antipsychotic agents. Synonyms: cis-Flupentixol; cis-(Z)-Flupentixol dihydrochloride; 2-[4-[(3Z)-3-[2-(trifluoromethyl)thioxanthen-9-ylidene]propyl]piperazin-1-yl]ethanol dihydrochloride; Emergil. Grades: ≥95%. CAS No. 51529-01-2. Molecular formula: C23H25F3N2OS·2HCl. Mole weight: 507.4. | |
| cis-Ned 19 | cis-Ned 19 is a irreversible nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist, which inhibits Ca2+ release (IC50 = 800 nM) and [32P]NAADP binding (IC50 = 15 μM). Ned-19 has two diastereomers, the 'trans' and 'cis', the trans form was more potent than the cis form in regard to both inhibition of Ca2+ release (IC50 of 6 nM versus 800 nM) and [32P]NAADP binding (IC50 of 0.4 nM versus 15 μM). Synonyms: cis-Ned 19; cis-Ned19; cis-Ned-19; (1S,3S)-1-[3-[[4-(2-Fluorophenyl)piperazin-1-yl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid. Grades: ≥97% by HPLC. CAS No. 1137264-00-6. Molecular formula: C30H31FN4O3. Mole weight: 514.59. | |
| CJ 033466 | CJ 033466 has been found to be a partial and selective 5-HT4 agonist and could exhibit gastroprokinetic effects in vivo. Synonyms: CJ 033466; CJ033466; CJ-033466; 5-Amino-6-chloro-2-methyl-N-[[1-(2-methylpropyl)-4-piperidinyl]methyl]-imidazo[1,2-a]pyridine-8-carboxamide. Grades: ≥98% by HPLC. CAS No. 519148-48-2. Molecular formula: C19H28ClN5O. Mole weight: 377.91. | |
| CJ-13610 | CJ-13610 is an inhibitor of 5-lipoxygenase (5-LO). It inhibits 5-LO product formation in human polymorphonuclear leukocytes (PMNLs) challenged with A23187 in vitro. It also inhibits 5-LO product formation induced by phosphorylation in PMNLs and HeLa cells. Synonyms: 4-[3-[4-(2-methylimidazol-1-yl)phenyl]sulfanylphenyl]oxane-4-carboxamide; Tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-2H-pyran-4-carboxamide. Grades: ≥98%. CAS No. 179420-17-8. Molecular formula: C22H23N3O2S. Mole weight: 393.5. | |
| CJ-42794 | CJ-42794 is a selective prostaglandin E receptor subtype 4 (EP4) antagonist. It inhibits [3H]-PGE2 binding to the human EP4 receptor with a mean pKi of 8.5. It competitively antagonized cAMP accumulation with a pA2 value of 8.7 in HEK293 cells overexpressing rat prostanoid EP4 receptors. It did not exhibit any remarkable binding to 65 additional proteins, including GPCRs, enzymes, and ion channels. It reversed the inhibitory effects of PGE2 on LPS-induced TNFα production in a concentration-dependent manner. It has excellent pharmacological properties that make it a useful tool for exploring the physiological role of EP4 receptors. Uses: Cj-42794 has excellent pharmacological properties that make it a useful tool for exploring the physiological role of ep4 receptors. Synonyms: CJ-042794; CJ 042794; CJ042794; RQ-00015986, RQ-15986. 4-[ (1S) -1-[[5-chloro-2- (4-fluorophenoxy) benzoyl]amino]ethyl]benzoic acid; (S) -4- (1- (5-chloro-2- (4-fluorophenoxy) benzaMido) ethyl) benzoic acid;CJ-042794;4-((S)-1-(2-(4-fluorophenoxy)-5-chlorobenzamido)ethyl)benzoic acid. Grades: >98%. CAS No. 847728-01-2. Molecular formula: C22H17ClFNO4. Mole weight: 413.83. | |
| CJ463 | CJ463 is a potent ans selective Urokinase (uPA) inhibitor, which plays a crucial role in carcinogenesis by facilitating tumor cell invasion and metastasis. It may be a novel agent for treatment of lung cancer. Uses: Cj463 may be a novel agent for treatment of lung cancer. Synonyms: CJ-463; CJ 463; CJ463. (S) -N- (4-carbamimidoylbenzyl) -3-hydroxy-2- ( (R) -3-hydroxy-2- ( (phenylmethyl) sulfonamido) propanamido) propanamide. Grades: 98%. CAS No. 600142-19-6. Molecular formula: C21H27N5O6S. Mole weight: 477.54. | |
| CK 3197 | CK 3197 is a Phosphoric diester hydrolase inhibitor originated by Bayer HealthCare Pharmaceuticals. CK 3197 has hemodynamic and myocardial energetic effects. In Jan 2007, preclinical for Heart failure in USA was discontinued. Uses: Heart failure. Synonyms: CK 3197; CK-3197; CK3197. 1-benzoyl-5-(4-(4,5-dihydro-2-methyl-1H-imidazol-1-yl)benzoyl)-4-ethyl-1,3-dihydro-2H-Imidazol-2-one. Grades: 98%. CAS No. 132523-92-3. Molecular formula: C23H22N4O3. Mole weight: 402.45. | |
| CKD-516 | This active molecular is a tubulin polymerisation inhibitor which is applicated for solid cancer treatment. CKD-516 disruptes tubulin of the endothelial cytoskeleton selectively. In Jun 2012, a South Korea company, Chong Kun Dang initiated enrolment in a phase I trial for solid tumours treatment in South Korea. In Dec 2014, Phase-I clinical trials in Solid tumours in South Korea was on going. Uses: Solid tumours. Synonyms: CKD-516 HCl; CKD 516 HCl; CKD516 HCl; (2S)-2-amino-3-methyl-N-[4-[3-(1,2,4-triazol-1-yl)-4-(3,4,5-trimethoxybenzoyl)phenyl]-1,3-thiazol-2-yl]butanamide;hydrochloride;1188371-47-2 (free base). Grades: 98%. CAS No. 1188371-47-2. Molecular formula: C26H28N6O5S. Mole weight: 536.6. | |
| CL 218872 | CL 218872 has been found to be a benzodiazepine agonist and has been found to exhibit anxiolytic and anticonvulsant activities. Synonyms: CL 218872; CL218872; CL-218872; 3-Methyl-6-[-3-(trifluoromethyl)phenyl]-1,2,4-triazolo[4,3-b]pyridazine. Grades: ≥99% by HPLC. CAS No. 66548-69-4. Molecular formula: C13H9F3N4. Mole weight: 278.24. | |
| CL-316243 | CL-316243 is a potent and highly selective β3-adrenoceptor agonist (EC50 = 3 nM) with > 10000-fold selective over β1 and β2 receptors. CL 316243 possesses anti-obesity and anti-diabetic effects due to increasing brown adipose tissue thermogenesis and metabolic rate, and consequently may be useful for treating obesity as well as non-insulin-dependent diabetes mellitus in obese persons, without causing excessive side effects. Synonyms: CL-316243; CL 316243; CL316243; 5-[(2R)-2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate; 138908-40-4 (CL-316243 sodium). Grades: >98%. CAS No. 183720-02-7. Molecular formula: C20H20ClNNa2O7. Mole weight: 419.794. | |
| CL 316243 disodium salt | The sodium salt form of CL 316243, which has been found to be a β3-adrenoceptor agonist and could probably decrease blood insulin as well as glucose levels. Synonyms: CL 316243 disodium salt; CL316243 disodium salt; CL-316243 disodium salt; 5-[(2R)-2-[[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylic acid disodium salt. Grades: ≥98% by HPLC. CAS No. 151126-84-0. Molecular formula: C20H18ClNNa2O7. Mole weight: 465.80. | |
| CL-316243 sodium | CL-316243 is a highly selective β3-adrenoceptor agonist with EC50 value of 3 nM; > 10000-fold selective over β1 and β2 receptors. CL-316243 can restore the expression of down-regulated fatty acid oxidation genes in type 2 diabetic mice and enhance insulin-stimulated glucose disposal in nonobese rats. Preclical trials for the treatment of Obesity, Overactive bladder and Type 2 diabetes mellitus were discontinued. Uses: Obesity; overactive bladder; type 2 diabetes mellitus. Synonyms: CL-316243 sodium; CL 316243 sodium; CL316243 sodium; disodium;5-[(2R)-2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate;BTA 243; HP 186; BTA243; HP186; BTA-243; HP-186. Grades: 98%. CAS No. 138908-40-4. Molecular formula: C20H18ClNNa2O7. Mole weight: 465.79. | |
| Cl-4AS-1 | Cl-4AS-1 is a mouse mammary tumor virus (MMTV) promoter and represses MMP1 promoter activity. It also inhibits 5α-Reductase type I and II with IC50 values of 6 and 10 nM respectively, as well as is a potent steroidal androgen receptor agonist with IC50 value of 12 nM. It mimics the action of 5α-dihydrotestosterone (DHT). Synonyms: (4aα, 4bβ, 6aα, 7α, 9aβ, 9bα, 11aβ)-N-(2-Chlorophenyl)-2, 4a, 4b, 5, 6, 6a, 7, 8, 9, 9a, 9b, 10, 11, 11a-tetradecahydro-1, 4, 6a-trimethyl-2-oxo-1H-indeno[5, 4-f]quinoline-7-carboxamide. Grades: ≥99% by HPLC. CAS No. 188589-66-4. Molecular formula: C26H33ClN2O2. Mole weight: 441.01. | |
| CL656 | CL656 is an agonist of stimulator of interferon genes (STING) for treating cancer. Synonyms: c-[2'FdAMP(S)-2'FdIMP(S)]; cAIM(PS)2 Difluor (Rp/Sp); Adenosine, 2'-deoxy-2'-fluoro-5'-O-(hydroxymercaptophosphinyl)-P-thioinosinylyl-(3'?5')-2'-deoxy-2'-fluoro-, cyclic nucleotide; CL 656; CL-656; (Rp/Sp) c-[2'FdAM(PS)-2'FdIM(PS]); 9-((2R, 3R, 3aR, 7aR, 9R, 10R, 10aR, 14aR)-9-(6-amino-9H-purin-9-yl)-3, 10-difluoro-12-hydroxy-5-mercapto-5-oxido-12-sulfidooctahydro-2H, 7H-difuro[3, 2-d:3', 2'-j][1, 3, 7, 9]tetraoxa[2, 8]diphosphacyclododecin-2-yl)-1, 9-dihydro-6H-purin-6-one. Grades: >98%. CAS No. 1951464-79-1. Molecular formula: C20H21F2N9O9P2S2. Mole weight: 695.51. | |
| CL 82,198 | CL 82,198 is a selective inhibitor of human collagenase-3, also known as matrix metalloproteinase-13 (MMP-13). It doesn't have effect against MMP-1, MMP-9 or TNF-α converting enzyme. CL 82,198 is also used to evaluate the role of MMP-13 in diverse processes, including cancer cell migration, acute lung injury, and joint degeneration associated with osteoarthritis. Synonyms: CL-82198; N-[4-(4-Morpholinyl)butyl]-2-benzofurancarboxamide. Grades: ≥95%. CAS No. 307002-71-7. Molecular formula: C17H22N2O3. Mole weight: 302.4. | |
| CL 82198 hydrochloride | The hydrochloride salt form of CL 82198, an inhibitor of MMP-13, has been found to restrain in vitro invasion by the human pituitary adenoma cell line HP75. Synonyms: CL 82198 hydrochloride; CL82198 hydrochloride; CL-82198 hydrochloride; N-[4-(4-Morpholinyl)butyl]-2-benzofurancarboxamide hydrochloride. Grades: ≥98% by HPLC. CAS No. 1188890-36-9. Molecular formula: C17H23N2O3.HCl. Mole weight: 338.83. | |
| Clazosentan | Clazosentan, also called as AXV 034, Ro 61-1790 or VML 588, a novel endothelin A antagonist, improves cerebral blood flow and behavior after traumatic brain injury. In 2016 Actelion plans two phase III trials of Clazosentan for Cerebral vasospasm (in patients with aneurysmal subarachnoid haemorrhage) in Japan. Synonyms: N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-[2-(2H-tetrazol-5-yl)pyridin-4-yl]pyrimidin-4-yl]-5-methylpyridine-2-sulfonamideAXV034; AXV-034; AXV 034; AXV 034343; AXV-034343; AXV-343434; Ro 61-1790; Ro-61-1790; VML 588; VML-588; VML 588; Clazosentan. Grades: 95%. CAS No. 180384-56-9. Molecular formula: C25H23N9O6S. Mole weight: 577.57. | |
| Clebopride Malate | Clebopride is a substituted benzamide as a dopamine antagonist used to treat functional gastrointestinal disorders. Uses: Dopamine antagonist. Synonyms: 4-Amino-5-chloro-2-methoxy-N-(1-benzyl-4-piperidyl)benzamide malate; 4-amino-N-(1-benzylpiperidin-1-ium-4-yl)-5-chloro-2-methoxybenzamide;2,4-dihydroxy-4-oxobutanoate. Grades: ≥95%. CAS No. 57645-91-7. Molecular formula: C23H28ClN3O6. Mole weight: 477.94. | |
| Clemastine | Clemastine is a histamine H1 antagonist commonly used for the symptoms of allergic rhinitis, hay fever, and cold. Uses: Anti-allergic agents. Synonyms: HS 592; HS-592; HS592; Meclastin; Mecloprodin; Clemastina; Tavist; Meclastine. CAS No. 15686-51-8. Molecular formula: C21H26ClNO. Mole weight: 343.895. | |
| Clemizole | Clemizole is an H1 antagonist acts as a TRPC5 channel blocker (IC50 values are 1.1, 6.4, 9.1, 11.3 and 26.5 μM for TRPC5, TRPC4, TRPC3, TRPC6 and TRPC7 respectively). Uses: Trpc5 channel blocker. Synonyms: Clemizole; NSC 46261; NSC-46261; NSC46261; 1-[(4-chlorophenyl)methyl]-2-(pyrrolidin-1-ylmethyl)benzimidazole. Grades: ≥95%. CAS No. 442-52-4. Molecular formula: C19H20ClN3. Mole weight: 325.8350. | |
| Clenhexerol | Clenhexerol is a β-adrenergic agonist. Synonyms: 1-(4-Amino-3,5-dichlorophenyl)-2-hexylaminoethanol. CAS No. 78982-88-4. Molecular formula: C14H22Cl2N2O. Mole weight: 305.243. | |
| Clenproperol | Clenproperol is a β-adrenergic agonist. Synonyms: 4-Amino-3, 5-dichloro-alpha- ( ( (1-methylethyl) amino) methyl) benzenemethanol. Grades: 98%. CAS No. 38339-11-6. Molecular formula: C11H16Cl2N2O. Mole weight: 263.16. | |
| Cl-HIBO | Cl-HIBO is a strongly desensitising and subtype-selective AMPA receptor agonist, which is a heterotetrameric transmembrane receptor and is found in various areas of the brain. It is selective for GluR1 and GluR2 subunit-containing receptors with EC50 values of 4.7 and 1.7 μM for rat recombinant homomeric GluR1 and 2 receptors respectively. It mediates fast synaptic transmission in the central nervous system. Synonyms: 4-Chlorohomoibotenic acid; (RS)-2-Amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)propionic acid; α-Amino-4-chloro-2,3-dihydro-3-oxo-5-isoxazolepropanoic Acid; 2-amino-3-(4-chloro-3-oxo-1,2-oxazol-5-yl)propanoic acid. Grades: ≥99% by HPLC. CAS No. 909400-43-7. Molecular formula: C6H7ClN2O4. Mole weight: 206.59. | |
| Clidinium Bromide | Clidinium bromide is an anticholinergic used as an antispasmodic to reduce stomach acid and decreases intestinal spasms. Uses: An anticholinergic. used as an antispasmodic. Synonyms: (1-methyl-1-azoniabicyclo[2.2.2]octan-3-yl) 2-hydroxy-2,2-diphenylacetate;bromide. Grades: 95%. CAS No. 3485-62-9. Molecular formula: C22H26BrNO3. Mole weight: 432.35. | |
| Climbazole | Climbazole is a topical antifungal agent commonly used in the treatment of human fungal skin infections such as dandruff and eczema. Climbazole has shown a high in vitro and in vivo efficacy against Pityrosporum ovale that appears to play an important role in the pathogenesis of dandruff. Synonyms: Crinipan AD;1-(4-chlorophenoxy)-3,3-dimethyl-1-(imidazol-1-yl)-butan-2-one;CLIMBAZOL;1-(4-chloro-phenoxy)-1-imidazol-1-yl-3,3-dimethyl-butan-2-one;1-(4-Chlorophenoxy)-1-(imidazol-1-yl)-3,3-dimethyl-2-butanone. Grades: >98%. CAS No. 38083-17-9. Molecular formula: C15H17ClN2O2. Mole weight: 292.76. | |
| Clobenpropit dihydrobromide | Clobenpropit dihydrobromide is a highly potent histamine H3 antagonist/inverse agonist (pA2=9.93) that can cross blood-brain barrier. It also displays partial agonist activity at H4 receptors. Synonyms: Carbamimidothioic acid, N-[(4-chlorophenyl)methyl]-, 3-(1H-imidazol-5-yl)propyl ester, hydrobromide (1:2); Carbamimidothioic acid, [(4-chlorophenyl)methyl]-, 3-(1H-imidazol-4-yl)propyl ester, dihydrobromide; Clobenpropit hydrobromide; 3-(1H-imidazol-5-yl)propyl (4-chlorobenzyl)carbamimidothioate dihydrobromide. Grades: ≥99% by HPLC. CAS No. 145231-35-2. Molecular formula: C14H17ClN4S.2HBr. Mole weight: 470.65. | |
| Clofibrate | Clofibrate is a fibric acid derivative used in the treatment of hyperlipoproteinemia type III and severe hypertriglyceridemia. Synonyms: Atromid-S. Grades: >98%. CAS No. 637-07-0. Molecular formula: C12H15ClO3. Mole weight: 242.7. | |
| Clofoctol | Clofoctol is a bacteriostatic antibiotic used to against gram-positive bacteria. Uses: A bacteriostatic antibiotic. Synonyms: 2-[(2,4-dichlorophenyl)methyl]-4-(2,4,4-trimethylpentan-2-yl)phenol. Grades: ≥98%. CAS No. 37693-01-9. Molecular formula: C21H26Cl2O. Mole weight: 365.34. | |
| Clomoxir | Clomoxir is a carnitine O-palmitoyltransferase inhibitor. Synonyms: 2-[5-(4-chlorophenyl)pentyl]oxirane-2-carboxylic acid; 2-Oxiranecarboxylicacid, 2-[5-(4-chlorophenyl)pentyl]-; Clomoxirum. CAS No. 88431-47-4. Molecular formula: C14H17ClO3. Mole weight: 268.737. | |
| Clopidogrel | Clopidogrel, a thienopyridine derivative, could be used in the prevention and treatment of sorts of arterial circulation disorders caused by platelet aggregation. Uses: Clopidogrel could be used in the prevention and treatment of sorts of arterial circulation disorders caused by platelet aggregation. Synonyms: Clopidogrel; Plavix; Zyllt; (S)-Clopidogrel; CLOPIDOGREL SULFATE. Grades: ≥98%. CAS No. 113665-84-2. Molecular formula: C16H16ClNO2S. Mole weight: 321.82. | |
| (±)-Clopidogrel hydrochloride | (±)-Clopidogrel hydrochloride is the hydrochloride salt of clopidogrel, which is a high affinity, selective and irreversible antagonist of the platelet purinergic P2Y12 receptor with IC50 value of 100 nM. It is used as a potent antithrombotic agent and requires bioactivation. It inhibits ADP-induced platelet aggregation ex vivo and functions as a prodrug. It enables its anti-aggregating activity via biotransformation to its active metabolite via CYP2C19 in the liver. Synonyms: Plavix; α-(2-chlorophenyl)-6,7-dihydro-thieno[3,2-c]pyridine-5(4H)-acetic acid, methyl ester, monohydrochloride; Methyl 2-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)-2-(2-chlorophenyl)acetate hydrochloride. Grades: ≥99% by HPLC. CAS No. 130209-90-4. Molecular formula: C16H17NO2SCl2. Mole weight: 358.28. | |
| Clopidogrel thiolactone | The thiolactone form of Clopidogrel that could be an effective antiplatelet agent for behaving as an inhibitor of P2Y12 receptor. Uses: The thiolactone form of clopidogrel that could be an effective antiplatelet agent for behaving as an inhibitor of p2y12 receptor. Synonyms: Clopidogrel thiolactone; 2-oxoclopidogrel; UNII-0IX303KU54; 2-oxo-clopidogrel; 0IX303KU54. Grades: 98%. CAS No. 1147350-75-1. Molecular formula: C16H16ClNO3S. Mole weight: 337.82. | |
| (+)-Cloprostenol methyl amide | (+)-Cloprostenol is a synthetic analog of prostaglandin F2α (PGF2α). It is an FP receptor agonist and a potent luteolytic agent in rats and hamsters. Synonyms: (+)-9alpha,11alpha,15R-Trihydroxy-16-(3-chlorophenoxy)-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-oic acid, methyl amide; (+)-16-m-Chlorophenoxy tetranor PGF2α methyl amide. Grades: ≥98%. Molecular formula: C23H32ClNO5. Mole weight: 438. | |
| (+)-Cloprostenol methyl ester | (+)-Cloprostenol is a synthetic analog of prostaglandin F2α (PGF2α). It is an FP receptor agonist and a potent luteolytic agent in rats and hamsters. Synonyms: Methyl (Z)-7-[(1R,2R,3R,5S)-2-[(E,3R)-4-(3-chlorophenoxy)-3-hydroxybut-1-enyl]-3,5-dihydroxycyclopentyl]hept-5-enoate; (+)-16-m-Chlorophenoxy tetranor PGF2α methyl ester. Grades: ≥98%. CAS No. 56687-85-5. Molecular formula: C23H31ClO6. Mole weight: 438.9. | |
| Clorgyline hydrochloride | Clorgyline is a potent monoamine oxidase (MAO) inhibitor that preferentially targets MAO-A over MAO-B (Kis = 0.054 and 58 μM, respectively). This inhibition is irreversible. Clorgyline is without effect on serotonin receptors, but it does inhibit the sigma receptor σ1 on Jurkat human T lymphocyte cells (IC50 = 31 nM). Synonyms: N-2,4-Dichlorophenoxypropyl-N-methylpropargylamine. Grades: ≥98%. CAS No. 17780-75-5. Molecular formula: C13H15Cl2NO·HCl. Mole weight: 308.6. | |
| Clorprenaline | Clorprenaline is a beta-adrenergic receptor agonist. Uses: Bronchodilator agents. Synonyms: 1-(2-Chlorophenyl)-2-isopropylaminoethanol. CAS No. 3811-25-4. Molecular formula: C11H16ClNO. Mole weight: 213.705. | |
| Clorsulon | Clorsulon is used in the treatment of Fasciola hepatica infections in calves and sheep. Synonyms: Clorsulon; Clorsulone; Clorsulonum; BRN 2821757; BRN2821757; BRN-2821757; L-631,529; L631,529; L 631,529; MK 401; MK-401; MK401. Grades: >98%. CAS No. 60200-06-8. Molecular formula: C8H8Cl3N3O4S2. Mole weight: 380.66. | |
| Closantel | Closantel is a gram positive antibacterial activity inhibitor, inhibiting the KinA/Spo0F system with IC50 of 3.8 μM. Synonyms: R-31520; R 31520; R31520. Grades: >98%. CAS No. 57808-65-8. Molecular formula: C22H14Cl2I2N2O2. Mole weight: 663.07. | |
| Closantel sodium | Closantel is a salicylaniline anthelmintic, which exhibits a different anthelmintic spectrum and obvious toxicity in mammals. Closamide sodium is widely used in various infections of the above-mentioned parasitic diseases in cattle and sheep. Synonyms: Closantel sodium; 61438-64-0; Closantel (sodium); 61438-64-0; (sodium)sodium 2-((5-chloro-4-((4-chlorophenyl)(cyano)methyl)-2-methylphenyl)carbamoyl)-4,6-diiodophenolate. Grades: >98%. CAS No. 61438-64-0. Molecular formula: C22H13Cl2I2N2NaO2. Mole weight: 685.06. | |
| Clozapine hydrochloride | Clozapine (HF 1854) is an antipsychotic used to treat schizophrenia. Clozapine is a potent antagonist of dopamine and a number of other receptors. Clozapine is also a potent and selective agonist at the muscarinic M4 receptor. Clozapine is a partial agonist of the serotonin (5-HT) receptor subtype 5-HT1A. It also binds to the 5-HT2A, 5-HT2C, 5-HT3, 5-HT6, and 5-HT7 receptors, as well as the histamine H1 and α1-adrenergic receptors. Synonyms: 8-chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine dihydrochloride; HF 1854 dihydrochloride. Grades: ≥98%. Molecular formula: C18H19ClN4·2HCl. Mole weight: 399.74. | |
| CM-352 | CM-352 has been found to be a MMP inhibitor that could probably be used as an antihemorrhagic agent with little influence in normal hemostatic function. Synonyms: CM352; CM 352; CM-352; (R) -N-hydroxy-2- ( (4- (4- (methylcarbamoyl) phenoxy) phenyl) sulfonyl) -8-azaspiro[4. 5]decane-2-carboxamide. Grades: 98%. CAS No. 1542205-83-3. Molecular formula: C24H29N3O6S. Mole weight: 487.57. | |
| CMA | CMA is a murine-selective agonist of STING. It triggers type I IFN response in murine macrophages, without effect on human STING signaling. Synonyms: 9-Oxo-10(9H)-acridineacetic acid. Grades: ≥98% by HPLC. CAS No. 38609-97-1. Molecular formula: C15H11NO3. Mole weight: 253.25. | |
| c-Met inhibitor 1 | c-Met inhibitor 1 is an inhibitor of the c-Met receptor signaling pathway useful for the treatment of cancer including gastric, glioblastoma, and pancreatic cancer. Synonyms: c-Met inhibitor 1; c Met inhibitor 1. Grades: >98%. CAS No. 1357072-61-7. Molecular formula: C17H14N8S. Mole weight: 362.41. | |
| CMI-392 | CMI-392 is a dual antagonist of 5-lipoxygenese (IC50= 100 nM) and platelet-activating factor (PAF) receptor (IC50= 10 nM). Uses: Lipoxygenase inhibitors. Synonyms: 3-[[2-[2-(4-chlorophenyl)sulfanylethoxy]-3-methoxy-5-[(2S,5S)-5-(3,4,5-trimethoxyphenyl)oxolan-2-yl]phenyl]methyl]-1-hydroxy-1-methylurea; 2-(3-methoxy-4-(4-chlorophenylthioethoxy)-5-(N-methyl-N-hydroxyureidyl)methylphenyl)-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran; CMI 392; CMI-392. CAS No. 205654-37-1. Molecular formula: C31H37ClN2O8S. Mole weight: 633.15. | |
| CMI-977 | CMI-977, an oxolan compound, has been found to be a 5-Lipoxygenases inhibitor and was once studied as an antiasthmatic agent. Synonyms: CMI-977; CMI 977; CMI977; LPD-977; LPD 977; LPD977; MLN-977; MLN977; MLN 977; 1-[4-[(2S,5S)-5-[(4-fluorophenoxy)methyl]oxolan-2-yl]but-3-ynyl]-1-hydroxyurea. Grades: 98%. CAS No. 175212-04-1. Molecular formula: C16H19FN2O4. Mole weight: 322.34. | |
| CMP8 | CMP8 is a selective ligand for the estrogen receptor, which can bind to the ligand binding domain of the estrogen receptor. The IC50 values of CMP8 for mutant MGERα, MGRERα and wild-type hERα and hERβ are 29 nM, 41 nM, 1100 nM and 2200 nM, respectively. Grades: 98%. CAS No. 851107-28-3. Molecular formula: C33H34ClNO3. Mole weight: 528.1. | |
| CMPD-1 | CMPD-1, also called MK2a Inhibitor, inhibits tubulin polymerisation. It inhibit p38α-mediated MK2a phosphorylation (apparent Ki = 330 nM). Synonyms: CMPD1; CMPD-1; CMPD 1; IN1225; IN-1225; IN 1225; 4-[4-(2-fluorophenyl)phenyl]-N-(4-hydroxyphenyl)butanamide; MK2a Inhibitor; MAPKAPK2a Inhibitor; CMPD1; CHEMBL235658; 41179-33-3; IN1225; 4-(2' -Fluorobiphenyl-4-yl)-N-(4-hydroxyphenyl)-butyramide; Mitogen-activated protein kinase-activated protein kinase 2a Inhibitor; MK2a Inhibitor_x000D_; SCHEMBL169905. CAS No. 41179-33-3. Molecular formula: C22H20FNO2. Mole weight: 349.4. | |
| CMPDA | CMPDA is a positive allosteric modulator of AMPA receptors. Binds at the modulator binding pocket located at the interdimer interface and the clamshell hinges. Synonyms: CMPDA; 380607-77-2; N,N'-(1,4-Phenylenedi-2,1-ethanediyl)bis-2-propanesulfonamide; A36XX25K37; N-[2-[4-[2- (propan-2-ylsulfonylamino) ethyl]phenyl]ethyl]propane-2-sulfonamide; N,N'-(Benzene-1,4-Diyldiethane-2,1-Diyl)dipropane-2-Sulfonamide; 2-Propanesulfonamide, N,N'-(1,4-phenylenedi-2,1-ethanediyl)bis-; UNII-A36XX25K37; SCHEMBL6565144; BCP23929; AKOS024458123; CS-3632; HY-12508; MS-26117; E99011; Q27465085; N,N'-(2,2'-(1,4-phenylene)bis(ethane-2,1-diyl))dipropane-2-sulfonamide; RNN. Grades: >98%. CAS No. 380607-77-2. Molecular formula: C16H28N2O4S2. Mole weight: 376.53. | |
| CNQX disodium salt | The sodium salt form of CNQX, which is an AMPA/kainate antagonist and could be used in studies of neurological disorders or damage. Synonyms: 6-Cyano-7-nitroquinoxaline-2,3-dione disodium. Grades: ≥99% by HPLC. CAS No. 479347-85-8. Molecular formula: C9H2N4O4Na2. Mole weight: 276.12. | |
| CNX-1351 | CNX-1351 is a selective covalent Inhibitor of PI3K&alpha. In an end point assay, CNX-1351 potently inhibited PI3Kα and was 20-400 times less potent against β, γ, and &delta. CNX-1351 inhibit PI3Kα signaling in cells and shows prolonged inhibition consistent with a covalent mechanism of Action. CNX-1351 inhibits growth of cells dependent on PI3K&alpha. CNX-1351 also inhibits PI3Kα signaling in vivo and bonds to p110&alpha. Synonyms: CNX-1351; CNX 1351; CNX1351. Grades: 0.98. CAS No. 1276105-89-5. Molecular formula: C30H35N7O3S. Mole weight: 573.716. | |
| CNX-774 | CNX-774 is a potent Btk inhibitor (IC50 < 1 nM). Synonyms: CNX-774; CNX 774; CNX774. CAS No. 1202759-32-7. Molecular formula: C26H22FN7O3. Mole weight: 499.49638. | |
| Co 101244 | Co 101244 is an N-methyl-D-aspartate NR2B subtype antagonist. Synonyms: 1-[2-(4-Hydroxyphenoxy)ethyl]-4-[(4-methylphenyl)methyl]-4-piperidinol; PD 174494; Ro 63-1908; Co 101244; PD 174494; Ro63-1908; Co101244; PD174494; Ro-63-1908; Co-101244. CAS No. 193359-26-1. Molecular formula: C21H27NO3. Mole weight: 341.45. | |
| Co 101244 hydrochloride | Co 101244 hydrochloride, with strongly neuroprotective effect in vivo and in vitro, is an ifenprodil-like noncompetitive, highly selective antagonist of NR2B-containing NMDA receptors (IC5= 43 nM). Synonyms: 1-[2-(4-hydroxyphenoxy)ethyl]-4-[(4-methylphenyl)methyl]piperidin-4-ol;hydrochloride; 4-hydroxy-N-(2-(4-hydroxyphenoxy)ethyl)-4-(4-methylbenzyl)piperidine; Co 101244; 193359-26-1 (Co 101244 free base); Co-101244; Co101244;PD 174494; PD-174494; PD174494. Grades: >98%. CAS No. 193356-17-1. Molecular formula: C21H27NO3.HCl. Mole weight: 377.91. | |
| Co 102862 | Co 102862, also known as V102862, an orally active anticonvulsant with robust activity, is a potent, broad-spectrum state-dependent inhibitor of mammalian voltage-gated Na+ channels with ~ 80-fold higher affinity for inactivated Na+ channels compared to channels in the resting state. Synonyms: CO-102862; CO 102862; CO102862; [[4- (4-fluorophenoxy) phenyl]methylideneamino]urea; 4-(4-fluorophenoxy)benzaldehyde semicarbazone; Co 102862; Co-102862; FPhOBal semicarbazone; 181144-66-1; 2- (4- (4-Fluorophenoxy) benzylidene) hydrazinecarboxamide; Hydrazinecarboxamide, 2-[[4-(4-fluorophenoxy)phenyl]methylene]-. Grades: >99 %. CAS No. 181144-66-1. Molecular formula: C14H12FN3O2. Mole weight: 273.26. | |
| CO-1686 hydrobromide | CO-1686 hydrobromide is the hydrobromide salt form of CO-1686. CO-1686, also called as Rociletinib, is an oral tyrosine kinase inhibitor that irreversibly and selectively inhibits mutation of EGFR for treating Non-small cell lung cancer.Non-small cell lun. Synonyms: N-[3-[[2-[4-(4-acetylpiperazin-1-yl)-2-methoxyanilino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]phenyl]prop-2-enamide;hydrobromide CO-1686 (hydrobromide) CO-1686 hydrobromide HY-15729A CS-5247 KB-310894 1446700-26-0. CAS No. 1446700-26-0. Molecular formula: C27H29BrF3N7O3. Mole weight: 636.46. | |
| CoA-S-acetyl-tryptamine | CoA-S-acetyl-tryptamine is a biomedical product exerting vital influence over specialized receptors implicated in neurotransmission. Molecular formula: C33H48N9O17P3S. Mole weight: 967.77. | |
| Cobimetinib hemifumarate | Cobimetinib, also known as GDC-0973 and XL-518, is a novel selective MEK inhibitor, and the IC50value against MEK1 is 4.2 nM, with potential antineoplastic activity. Synonyms: Methanone, [3,?4-difluoro-2-[(2-fluoro-4-iodophenyl)?amino]?phenyl]?[3-hydroxy-3-(2S)?-2-piperidinyl-1-azetidinyl]?-, (2E)?-2-butenedioate (2:1). CAS No. 1369665-02-0. Molecular formula: C21H21F3IN3O2.1/2C4H4O4. Mole weight: 589.35. | |
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