BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Deoxycorticosterone acetate | Deoxycorticosterone acetate is a steroid hormone used for intramuscular injection for replacement therapy of the adrenocortical steroid. Synonyms: Deoxycorticosterone Acetate; DOCA; Percotol; Cortexone acetate. Grades: >98%. CAS No. 56-47-3. Molecular formula: C23H32O4. Mole weight: 372.5. |  |
| Dephospho CoA | Dephospho CoA is an indispensable enzymatic coenzyme exhibiting multifaceted participation in diverse intricate biochemical processes. With its pivotal involvement in lipid and carbohydrate metabolism, it assumes the vital role of serving as a precursor for the synthesis of acetyl-CoA. Functioning as an augmenter in the elimination of phosphates, it facilitates the degradation and utilization of adipose tissue-derived lipids and saccharides. Synonyms: Dephospho Coenzyme A; 3'-dephospho-CoA; [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [ (3R) -3-hydroxy-2, 2-dimethyl-4-oxo-4-[[3-oxo-3- (2-sulfanylethylamino) propyl]amino]butyl] hydrogen phosphate. CAS No. 3633-59-8. Molecular formula: C21H35N7O13P2S. Mole weight: 687.55. | |
| Dequalinium Chloride | Dequalinium Chloride is a PKC inhibitor with IC50 of 7-18 μM, and also a selective blocker of apamin-sensitive K+ channels with IC50 of 1.1 μM. Synonyms: Dequalinium chloride; Dequavagyn; NSC 166454; NSC-166454; NSC166454. Grades: >98%. CAS No. 522-51-0. Molecular formula: C30H40N4.2Cl. Mole weight: 527.57. | |
| Deracoxib | Deracoxib is a non-steroidal anti-inflammatory drug (NSAID) of the coxib class. Deracoxin is a selective cyclooxygenase-2 (COX-2) inhibitor used in the treatment of osteoarthritis in dogs. At low doses, adminsitartion of Deracoxin showed no factors associated with gastrointestinal tract perforation. Synonyms: Deram; Deramaxx; SC 046; SC 46; SC 59046. Grades: >98%. CAS No. 169590-41-4. Molecular formula: C17H14F3N3O3S. Mole weight: 397.37. | |
| Derrubone | Derrubone is a prenylated isoflavone, a type of flavonoid. It was originally isolated from the Indian tree Derris robusta.It has potential application as an inhibitor of Hsp90 to its function as a chaperone protein. Synonyms: 5,7-Dihydroxy-3',4'-methylenedioxy-6-prenylisoflavone. Grades: >98%. CAS No. 22044-58-2. Molecular formula: C21H18O6. Mole weight: 366.37. | |
| Deserpidine | Deserpidine is an antihypertensive drug related to Reserpine. It is naturally found in Rauvolfia spp. Deserpidine is a competitive ACE (angiotensin converting enzyme) inhibitor. Deserpidine can block the conversion of angiotensin I to angiotensin II as a potent vasoconstrictor through competing with angiotensin I for ACE. Reduced level of serum angiotensin II leads to a decrease in blood pressure. Deserpidine can also decrease angiotensin II-induced aldosterone secretion by the adrenal cortex. Uses: Antihypertensive drug. Synonyms: (3β, 16β, 17α, 18β, 20α)-17-methoxy-18-[(3, 4, 5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic Acid Methyl Ester; Deserpidic Acid Methyl Ester 3,4,5-Trimethoxybenzoate; Deserpidin; 1-Demethoxyreserpine; 11-Desmethoxyreserpine; Canescin; Canescine; Canescine (Rauwolfia); Harmonyl; NSC 72138; Raunormin; Raunormine; Recanescin; Recanescine; Reserpidine. Grades: 95%. CAS No. 131-01-1. Molecular formula: C32H38N2O8. Mole weight: 578.66. | |
| Desfesoterodine fumarate | Desfesoterodine is the active metabolite of fesoterodine as its isobutyrate ester. Uses: Muscarinic m3 receptor antagonists. Synonyms: PNU-200577 fumarate; (R)-2-[3-(diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)phenol fumaric acid salt. Grades: ≥98%. CAS No. 380636-50-0. Molecular formula: C22H31NO2. Mole weight: 341.5. | |
| Desformylflustrabromine hydrochloride | The hydrochloride salt form of Desformylflustrabromine, which has been found to be a positive allosteric modulator of α4β2 nicotinic acetylcholine receptors. Synonyms: 1H-Indole-3-ethanamine, 6-bromo-2-(1,1-dimethyl-2-propen-1-yl)-N-methyl-, hydrochloride (1:1); Desformylflustrabromine monohydrochloride; 6-Bromo-2-(1,1-dimethyl-2-propenyl)-N-1H-indole-3-ethanamine hydrochloride. Grades: ≥98% by HPLC. CAS No. 951322-11-5. Molecular formula: C16H21BrN2.HCl. Mole weight: 357.72. | |
| des-Gln14-Ghrelin (rat) | Des-Gln14-Ghrelin (rat) is an endogenous ligand for the ghrelin receptor (GHS-R1a), produced by alternative splicing of the rat ghrelin gene. It induces Ca2+ release in cells expressing ghrelin receptors (EC50 = 2.4 nM) and GH release in vivo. Synonyms: des-Gln14-Ghrelin (rat); des Gln14 Ghrelin (rat). CAS No. 293735-04-3. Molecular formula: C142H237N43O40. Mole weight: 3186.7. | |
| des-His1-[Glu9]-Glucagon (1-29) amide | A glucagon receptor antagonist (pA2 = 7.2 for inhibition of glucagon-induced adenylyl cyclase activation in rat liver membranes) that displays no agonist activity. It binds to glucagon receptors to stimulate breakdown of inositol phospholipids by phospholipase C. It was shown to potentiate glucose-stimulated pancreatic insulin release in vitro. It blocks added glucagon-induced hyperglycemia in normal rabbits without affecting glycogenolysis in vivo. Also blocks endogenous glucagon-induced hyperglycemia in streptozocin diabetic rats. Synonyms: (Des-His1,Glu9)-Glucagon (1-29) amide (human, rat, porcine); H-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Glu-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-NH2; L-seryl-L-glutaminyl-glycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-glutamyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-alpha-aspartyl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-glutaminyl-L-alpha-aspartyl-L-phenylalanyl-L-valyl-L-glutaminyl-L-tryptophyl-L-leucyl-L-methionyl-L-asparagyl-L-threoninamide. Grades: ≥95%. CAS No. 110084-95-2. Molecular formula: C148H221N41O47S. Mole weight: 3358.68. | |
| Desmethyl-S 14506 | Desmethyl-S 14506 is a precursor for S 14506, a 5-HT1A agonist, which can be used for PET study. Synonyms: 4-fluoro-N-[2-[4-(7-hydroxynaphthalen-1-yl)piperazin-1-yl]ethyl]benzamide. Grades: 98%. CAS No. 135722-26-8. Molecular formula: C23H24FN3O2. Mole weight: 393.45. | |
| Desmethyl SCH 442416 | Desmethyl SCH 442416 is a precursor to [11C]SCH 442416 for PET studies. SCH 442416 is a potent and brain-permeable A2A adenosine receptor antagonist. Desmethyl SCH 442416 is less potent and less selective in binding the A2A receptor compared to SCH 445416 (Ki values 44 nM, 48 nM, and 34 nM for A1, A2A and A3, respectively). Synonyms: SCH 442416, SCH442416; SCH-442416; Desmethyl. Grades: 95%. CAS No. 188112-92-7. Molecular formula: C19H17N7O2. Mole weight: 375.38. | |
| Desmethyl-VS-5584 | Desmethyl-VS-5584, a demethyl analogue of VS-5584, is a PI3K/mTOR kinase inhibitor for the treatment of cancer. Synonyms: 5-[9-(1-Methylethyl)-2-(4-morpholinyl)-9H-purin-6-yl]-2-pyrimidinamine; Desmethyl-VS-5584; Desmethyl-VS5584. CAS No. 1246535-95-4. Molecular formula: C16H20N8O. Mole weight: 340.39. | |
| desmethyl-WAY 100635 trihydrochloride | Desmethyl-WAY 100635 trihydrochloride is a precursor for labeling the 5-HT1A antagonist WAY 100635 and can be used for PET radioligand. Synonyms: DWAY; Cyclohexanecarboxylic acid {2-[4-(2-hydroxy-phenyl)-piperazin-1-yl]-ethyl}-pyridin-2-yl-amide trihydrochloride. Grades: 98%. CAS No. 2108805-94-1. Molecular formula: C24H32N4O2.3HCl. Mole weight: 517.92. | |
| Desmethyl-YM 298198 | Desmethyl-YM 298198 is a derivative of YM 298198, a selective antagonist of mGlu1. Synonyms: 6-Amino-N-cyclohexyl-3-methylthiazolo[3,2-a]benzimidazole-2-carboxamide hydrochloride. Grades: ≥98% by HPLC. CAS No. 1177767-57-5. Molecular formula: C17H20N4OS.HCl. Mole weight: 364.89. | |
| Dexamethasone phosphate sodium salt | Cas No. 2392-39-4. | |
| dexbrompheniramine | Dexbrompheniramine is an histamine H1-receptor antagonist used for the treatment of allergic conditions including hay fever or urticaria. It is the pharmacologically active dextrorotatory isomer of brompheniramine. Dexbrompheniramine is a first generation antihistamine that reduces the effects of natural chemical histamine in the body including the symptoms like sneezing, itching, watery eyes, and runny nose. Uses: Allergic conditions. Synonyms: DEXBROMPHENIRAMINE; DEXBROMPHENIRAMINE BASE;D-Brompheniramine;(S)-Brompheniramine;(S)-γ-(4-Bromophenyl)-N,N-dimethyl-2-pyridinepropan-1-amine;Disomer. Grades: 95%. CAS No. 132-21-8. Molecular formula: C16H19BrN2. Mole weight: 319.24. | |
| Dexibuprofen lysine | Dexibuprofen is a Cyclooxygenase inhibitor originated by Gebro Pharma GmbH. It is a non-steroidal anti-inflammatory drug as the active dextrorotatory enantiomer of ibuprofen. Dexibuprofen can be used for the treatment of Postoperative pain. Uses: Postoperative pain. Synonyms: Dexibuprofen lysine; Doctrin; L 669455; L-669,455; Dexibuprofen lysine; MK 233; MK233; MK-233; UNII-T179MT9211; (+)-(S)-p-Isobutylhydratropic acid, compound with L-lysine (1:1), monohydrate. Grades: 95%. CAS No. 141505-32-0. Molecular formula: C19H34N2O5. Mole weight: 370.48. | |
| DFB | DFB is a selective allosteric potentiator of the metabotropic glutamate receptor mGlu5. DFB exhibits no agonistic activity itself, but potentiates (3 - 6-fold) the action of agonists at mGlu5 devoid of any effect at other mGlu subtypes (EC50 for potentiation = 2 - 5.3 μM). Synonyms: [(3-Fluorophenyl)methylene]hydrazone-3-fluorobenzaldehyde; 3,3'-Difluorobenzaldazine. Grades: ≥99% by HPLC. CAS No. 15332-10-2. Molecular formula: C14H10F2N2. Mole weight: 244.24. | |
| DG 041 | DG 041 inhibits PGE2 facilitation of platelet aggregation in vitro and ex vivo. Displays good plasma and metabolic stability. Synonyms: (2E)-3-[1-[(2,4-Dichlorophenyl)methyl]-5-fluoro-3-methyl-1H-indol-7-yl]-N-[(4,5-dichloro-2-thienyl)sulfonyl]-2-propenamide;DTSI; UNII-1844425CLP. Grades: ≥98%. CAS No. 861238-35-9. Molecular formula: C23H15Cl4FN2O3S2. Mole weight: 592.32. | |
| DG5128 | DG5128, a new oral hypoglycemic agent, is an orally available preferential antagonist of α2-adrenoceptor with 7.4 times higher affinity toward α2-adrenoceptor than α1-adrenoceptor. Synonyms: 2-[2-(4, 5-dihydro-1H-imidazol-2-yl)-1-phenylethyl]pyridine; dihydrochloride; 2-(2-(4,5-dihydro-1H-imidazol-2-yl)-1-phenylethyl)pyridine dihydrochloride sesquihydrate; DG 5128; DG-5128; midaglizole; midaglizole dihydrochloride. CAS No. 79689-25-1. Molecular formula: C16H19Cl2N3. Mole weight: 324.25. | |
| DGAT1-IN-1 | Imidazopyridine and imidazothiazole compounds as inhibitors of diacylglycerol o-acyltransferase type 1 enzyme and their preparation. Synonyms: DGAT1-IN-1; DGAT1 IN 1. Grades: >98%. CAS No. 1449779-49-0. Molecular formula: C30H28F3N3O4. Mole weight: 551.56. | |
| DGAT-1 inhibitor 2 | DGAT-1 inhibitor 2 is an effective inhibitor of DGAT-1, which is one of two known DGAT enzymes that catalyze the final step in triglyceride synthesis. It is a promising strategy for the treatment of obesity and type 2 diabetes. Synonyms: DGAT-1 inhibitor; DGAT 1 inhibitor; Bicyclo[2.2.2]octane-1-acetic acid, 4-[4-(4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]-. Grades: >98%. CAS No. 942999-61-3. Molecular formula: C24H28N4O3. Mole weight: 420.5. | |
| DH 97 | DH 97 is a potent MT2 melatonin receptor antagonist (pKi = 8.03) with 89- and 229-fold selectivity over MT1 and GPR50 (melatonin-related orphan receptor) respectively. Synonyms: DH-97; DH 97; DH97; N-Pentanoyl-2-benzyltryptamine; N-[2-(2-benzyl-1H-indol-3-yl)ethyl]pentanamide. CAS No. 220339-00-4. Molecular formula: C22H26N2O. Mole weight: 334.46. | |
| diABZI STING agonist-1 | diABZI STING agonist-1 is a selective agonist of stimulator of interferon genes (STING) receptor, with EC50s of 130, 186 nM for human and mouse, respectively. Synonyms: 1H-Benzimidazole-5-carboxamide, 1-[(2E)-4-[5-(aminocarbonyl)-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]-7-methoxy-1H-benzimidazol-1-yl]-2-buten-1-yl]-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]-7-[3-(4-morpholinyl)propoxy]-; (E)-1-(4-(5-carbamoyl-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-(3-morpholinopropoxy)-1H-benzo[d]imidazol-1-yl)but-2-en-1-yl)-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-methoxy-1H-benzo[d]imidazole-5-carboxamide; STING agonist compound 3; 1-[(2E)-4-[5-(Aminocarbonyl)-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]-7-methoxy-1H-benzimidazol-1-yl]-2-buten-1-yl]-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]-7-[3-(4-morpholinyl)propoxy]-1H-benzimidazole-5-carboxamide. Grades: >98%. CAS No. 2138299-33-7. Molecular formula: C42H51N13O7. Mole weight: 849.94. | |
| diABZI STING agonist-1-trihydrochloride | Cas No. 2138299-34-8. | |
| Diarylpropionitrile | Diarylpropionitrile, also called as DPN, is a selective agonist of estrogen receptor β (ERβ) with a 70-fold higher relative binding affinity for ERβ(18%) versus ER (0.25%). ERβ: EC50=0.85 nM; ERα: EC50=66 nM. Synonyms: 2, 3-BIS(4-HYDROXYPHENYL)-PROPIONITRILE; DPN; 2, 3-bis(p-hydroxyphenyl)propionitrile; propionitrile, 2, 3-bis(p-hydroxyphenyl); 2, 3-Bis(4-hydroxyphenyl)propanenitrile; 2, 3-Bis(4-hydroxyphenyl)propiononitrile; Diarylpropionitrile. Grades: >99 %. CAS No. 1428-67-7. Molecular formula: C15H13NO2. Mole weight: 239.27. | |
| Diazoline | Diazoline is used for symptomatic relief of allergic symptoms caused by histamine release, including nasal allergies and allergic dermatosis. Synonyms: Mebhydrolin napadisylate; Omeril; Diazolin; Incidal; mebhydroline 1,5-naphthalenedisulfonate. Grades: 98% (HPLC). CAS No. 6153-33-9. Molecular formula: C48H48N4O6S2. Mole weight: 841.04. | |
| Dicyclomine hydrochloride | Dicyclomine is an M1 and M2 muscarinic acetylcholine receptor antagonist. It inhibits inositol phosphate accumulation induced by the non-selective acetylcholine agonist carbamoylcholine (carbacho) in guinea pig cortex. Dicyclomine inhibits potassium-induced contraction of ileum, colon, and duodenum in anesthetized rats. Formulations containing dicyclomine have been used to treat functional and irritable bowel syndrome and to relieve muscle spasms in the gastrointestinal tract. Uses: Parasympatholytics. Synonyms: Dicycloverine; Dicyclomine HCl; Bentyl. Grades: ≥98%. CAS No. 67-92-5. Molecular formula: C19H35NO2·HCl. Mole weight: 346. | |
| Dicycloverine (Dicyclomine) | Dicycloverine, also known as dicyclomine, is an anticholinergic that blocks muscarinic receptors. Grades: >95%. CAS No. 77-19-0. Molecular formula: C19H35NO2. Mole weight: 309.49. | |
| Didox | Didox, synthetic antioxidant, is a strong inhibitor of ribonucleotide reductase (RR) that has been found to reduce the levels of oxidative injury markers in the brains of HIV patients with dementia. Uses: Has been found to reduce the levels of oxidative injury markers in the brains of hiv patients with dementia. Synonyms: 3,4-Dihydroxybenzohydroxamic acid; N,3,4-Trihydroxybenzamide. Grades: ≥95%. CAS No. 69839-83-4. Molecular formula: C7H7NO4. Mole weight: 169.13. | |
| DIDS disodium salt | DIDS disodium salt is a stilbene sulfonate that acts as a ClC-Ka chloride channel blocker (IC50 = 100 μM). It blocks the maxi chloride channel in apical membranes from human placenta to inhibit the Cl- uptake. DIDS also has antagonistic activity at TRPM4 and TRPC4 channels. Synonyms: 4,4'-Diisothiocyanato-2,2'-stilbenedisulfonic acid disodium salt. Grades: ≥95% by HPLC. CAS No. 67483-13-0. Molecular formula: C16H8N2Na2O6S4. Mole weight: 498.48. | |
| Diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate | Diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate (DDC) inhibits heme production by inhibiting ferrochelatase, the enzyme that catalyzes the addition of Fe2+ to protoporphyrin IX to create heme B. Synonyms: diethyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate. Grades: ≥ 98 %. CAS No. 632-93-9. Molecular formula: C14H21NO4. Mole weight: 267.32. | |
| Diethyl maleate | Diethylmaleate, a glutathione-depleting compound, is the diethyl ester of maleic acid and inhibits NF-kB. It is used as a reagent in the synthesis of several organic compounds including that of polyaspartic acid ester based polyurea coatings. Uses: Used in organic synthesis and as a flavoring agent. Synonyms: diethyl (Z)-but-2-enedioate. Grades: 99.07 %. CAS No. 141-05-9. Molecular formula: C8H12O4. Mole weight: 172.18. | |
| Diethylstilbestrol | Diethylstilbestrol, a synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. Synonyms: Diethylstilbestrol; Stilbestrol; Stilboestrol; 56-53-1; Distilbene; Stilboestroform. Grades: >98%. CAS No. 56-53-1. Molecular formula: C18H20O2. Mole weight: 268.35. | |
| Difenoconazole | Pestanal is a broad spectrum fungicide. Synonyms: 1-[[2-[2-Chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1H-1,2,4-triazole. Grades: > 95%. CAS No. 119446-68-3. Molecular formula: C19H17Cl2N3O3. Mole weight: 406.26. | |
| Diflapolin | Diflapolin is a dual inhibitor of 5-lipoxygenase-activating protein (FLAP) and soluble epoxide hydrolase (sEH). It is selective for FLAP and sEH over other arachidonic acid metabolism enzymes. Diflapolin (1, 3, and 10 mg/kg) decreases inflammation in a mouse model of peritonitis induced by zymosan, reducing the production of LTB4 and LTC4 and inhibiting leukocyte recruitment. Grades: ≥98%. CAS No. 724453-98-9. Molecular formula: C22H17Cl2N3O2S. Mole weight: 458.36. | |
| Digitoxigenin | Digitoxigenin is a cardenolide and aglycone constituent of digitoxin, an extract from the foxglove plant, D. purpurea. Digitoxigenin is highly cytotoxic, inhibiting Na+/K+ ATPase-dependent protein synthesis, and has been examined for use as an antitumor compound. Synonyms: Cerberigenin; (+)-Digitoxigenin; Echujetin; Evonogenin; NSC 407806; Thevetigenin. Grades: ≥95%. CAS No. 143-62-4. Molecular formula: C23H34O4. Mole weight: 374.5. | |
| Dihomo-γ-linolenoyl ethanolamide | Dihomo-γ-linolenoyl ethanolamide is an endocannabinoid containing dihomo-γ-linoleate in place of the arachidonate moiety of AEA. Dihomo-γ-linolenoyl ethanolamide binds to recombinant human CB1 and CB2 receptors. Its specific role and relative importance as a cannabinergic neurotransmitter has not been elucidated. Synonyms: HGLEA; Homo-gamma-linolenylethanolamide; Anandamide (20.3,n-6); N-homo-gamma-linolenoylethanolamine. Grades: ≥98%. CAS No. 150314-34-4. Molecular formula: C22H39NO2. Mole weight: 349.6. | |
| Dihydrexidine hydrochloride | The hydrochloride salt form of Dihydrexidine, which has been found to be an effective full efficacy dopamine D1 agonist and show antiparkinsonism effects in vivo. Synonyms: (±)-trans-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine hydrochloride. Grades: ≥98% by HPLC. CAS No. 158704-02-0. Molecular formula: C17H17NO2.HCl. Mole weight: 303.79. | |
| Dihydro-β-erythroidine hydrobromide | The hydrobromide salt form of Dihydro-β-erythroidine, which is a competitive nAChR antagonist and has been found to show antagonizes behavioral effects of nicotine in vivo. Synonyms: (2S,13bS)-2-Methoxy-2,3,5,6,8,9,10,13-octahydro-1H,12H-benzo[i]pyrano[3,4-g]indolizin-12-one hydrobromide. Grades: ≥98% by HPLC. CAS No. 29734-68-7. Molecular formula: C16H21NO3.HBr. Mole weight: 356.26. | |
| Dihydrochlamydocin | Dihydrochlamydocin is a cyclic tetrapeptide with putative histone deacetylase (HDAC) inhibitory effect. Naturally derived cyclic tetrapeptides and their synthetic analogs have demonstrated potent antiparasitic and phytotoxic activity by inhibiting HDACs. Synonyms: CHEMBL474318; (3S,9S,12R)-3-Benzyl-9-[(7R)-7-hydroxy-6-oxooctyl]-6,6-dimethyl-1,4,7,10-tetrazabicyclo[10.3.0]pentadecane-2,5,8,11-tetrone; SCHEMBL17072219; DTXSID501017904; BDBM50588306. Grades: ≥95%. CAS No. 157618-75-2. Molecular formula: C28H40N4O6. Mole weight: 528.6. | |
| Dihydroergotamine mesylate | The mesylate salt form of Dihydroergotamine, which has been found to be a partial α-adrenergic agonist and could be used as an antimigraine agent. Synonyms: 9,10-Dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)ergotaman-3',6',18-trione mesylate. Grades: ≥98% by HPLC. CAS No. 6190-39-2. Molecular formula: C33H37N5O5.CH3SO3H. Mole weight: 679.79. | |
| Dihydrosanguinarine | Dihydrosanguinarine (DHSG) is a metabolite of Sanguinarine with antifungal activity. Synonyms: 13,14-Dihydrosanguinarine. Grades: >98%. CAS No. 3606-45-9. Molecular formula: C20H15NO4. Mole weight: 333.34. | |
| Dilept | Dilept is an antagonist of neurotensin (NT) and dopamine (DA) receptor used to mitigate positive and negative symptoms of schizophrenia. Uses: Schizophrenia treatment. Synonyms: N-caproyl-l-prolyl-l-tyrosine methyl ester; methyl (2S)-2-[[(2S)-1-hexanoylpyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoate. Grades: 99%. CAS No. 200954-39-8. Molecular formula: C21H30N2O5. Mole weight: 390.47. | |
| Diloxanide furoate | Diloxanide furoate is an ambecide used to treat infection with amoebas. Uses: An ambecide, an anti-protozoal drug used in the treatment of amoebozoa infections. Synonyms: Furamide; 4-[(Dichloroacetyl)methylamino]phenyl 2-Furancarboxylic Acid Ester; 2-Furoic Acid Ester with 2,2-Dichloro-4'-hydroxy-N-methylacetanilide. Grades: ≥95%. CAS No. 3736-81-0. Molecular formula: C14H11Cl2NO4. Mole weight: 328.15. | |
| Diltiazem | Diltiazem is a nondihydropyridines (non-DHP) calcium channel blocker used in the treatment of hypertension, angina pectoris, and some types of arrhythmia as a potent vasodilator, increasing blood flow and variably decreasing the heart rate via strong depression of A-V node conduction. Uses: A nondihydropyridines (non-dhp) calcium channel blocker. Synonyms: Cardizem; D-cis-Diltiazem; [(2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate. Grades: ≥95%. CAS No. 42399-41-7. Molecular formula: C22H26N2O4S. Mole weight: 414.52. | |
| Diltiazem Malate | Diltiazem is a calcium channel antagonist. It can relax the smooth muscles in the walls of arteries, allow blood to flow more easily, and lower blood pressure. Meanwhile, it can lower blood pressure through acting on the heart itself to reduce the rate, strength, and conduction speed of each beat. Diltiazem can be used in the treatment of hypertension, angina pectoris, and some types of arrhythmia. Uses: Hypertension, angina pectoris, and some types of arrhythmia. Synonyms: MK-793; MK 793; MK793; Tiamate; UNII-14Y6444DRP.;(+)-(2S,3S)-5-(2-(Dimethylamino)ethyl)-2,3-dihydro-3-hydroxy-2-(p-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one acetate (ester),(S)-malate (1:1);1,5-Benzothiazepin-4(5H)-one, 3-(acetyloxy)-5-(2-(di-methylamino)ethyl)-2,3-dihydro-2-(4-methoxyphenyl)-(2S-cis)-, (S)-hydoxybutanedioate (1:1). Grades: 98%. CAS No. 144604-00-2. Molecular formula: C26H32N2O9S. Mole weight: 548.61. | |
| Dimaprit dihydrochloride | The hydrochloride salt form of Dimaprit, which has been found to be a histamine H2 receptor agonist. Uses: Histamine agonists. Synonyms: S-(3-Dimethylaminopropyl)isothiourea dihydrochloride. Grades: ≥99% by HPLC. CAS No. 23256-33-9. Molecular formula: C6H15N3S.2HCl. Mole weight: 234.19. | |
| Dimethylenastron | Dimethylenastron is an inhibitor of mitotic motor kinesin Eg5 (IC50 = 200 nM).The inhibition of kinesin Eg5 by small molecules such as monastrol is currently evaluated as an approach to develop a novel class of antiproliferative drugs for the treatment of malignant tumours. Synonyms: Dimethylenastron. Grades: 98%. CAS No. 863774-58-7. Molecular formula: C16H18N2O2S. Mole weight: 302.39. | |
| Dimethyl-W84 dibromide | Dimethyl-W84 is a selective allosteric modulator of the M2 muscarinic acetylcholine receptor. It hinders the dissociation of the orthosteric antagonist N-methylscopolamine from the M2 receptor. Synonyms: Dimethyl-W84 (dibromide); 402475-33-6; 6-[dimethyl-[3-(5-methyl-1,3-dioxoisoindol-2-yl)propyl]azaniumyl]hexyl-dimethyl-[3-(5-methyl-1,3-dioxoisoindol-2-yl)propyl]azanium; dibromide; CHEMBL268194; AKOS040756231; N1,N1,N6,N6-Tetramethyl-N1,N6-bis(3-(5-methyl-1,3-dioxoisoindolin-2-yl)propyl)hexane-1,6-diaminium bromide. Grades: ≥98%. CAS No. 402475-33-6. Molecular formula: C34H48N4O4·2Br. Mole weight: 736.6. | |
| Dioxadrol hydrochloride | Dioxadrol hydrochloride has been found to be an NMDA antagonist and is used as a dissociative anaesthetic drug. It produces similar effects to PCP in animals. It was developed as analgesics for use in humans, but it was discontinued after patients reported side effects such as nightmares and hallucinations. Uses: Dioxadrol hydrochloride is used as a dissociative anaesthetic drug. Synonyms: D-2-(2,2-Diphenyl-1,3-dioxolan-4-yl)piperidine hydrochloride;D-2,2-Diphenyl-4-(2-piperidyl)-1,3-dioxolane hydrochloride;D-Dioxadrol hydrochloride;Dexoxadrol HCl;(2S)-2-[(4S)-2,2-diphenyl-1,3-dioxolan-4-yl]piperidine hydrochloride;NSC 526062; NSC-526062; Relane ; U 22558 A; d-Dioxadrol hydrochloride; Dexoxadrol HCl; U-22,559A;UNII-T0C1IR71L8. Grades: 98%. CAS No. 631-06-1. Molecular formula: C20H24ClNO2. Mole weight: 345.86. | |
| Diphenhydramine | A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects. Synonyms: Benadryl; Alledryl; Benzhydramine; Probedryl; PM255; PM-255; Dabylen; Debendrin. Grades: 98% (HPLC). CAS No. 58-73-1. Molecular formula: C17H21NO. Mole weight: 255.35. | |
| Diphenhydramine HCl | Cas No. 147-24-0. | |
| Diphenidine hydrochloride | Diphenidine is a homeomorph of the NMDA receptor channel blocker, MK 801, that has been identified as a designer drug. It has been studied as a neuroprotective agent for the treatment of brain injury following hypoxia. Synonyms: DEP; 1-(1,2-diphenylethyl)piperidine;dl-1,2-Diphenyl-1-piperidinoethane hydrochloride; (+-)-1-(1,2-Diphenylethyl)piperidine hydrochloride; Piperidine, 1-(1,2-diphenylethyl)-, hydrochloride, (+-)-; Diphenidine Hydrochloride. Grades: ≥98%. CAS No. 28383-15-5. Molecular formula: C19H23N·HCl. Mole weight: 301.9. | |
| Diphenidol hydrochloride | Diphenidol HCl is a potent antagonist of muscarinic M2 and M3 receptor with pKb of 6.72 and 7.02, respectively, used in the treatment of vomiting and vertigo. Uses: Antiemetics. Synonyms: Diphenidol hydrochloride. Grades: >98%. CAS No. 3254-89-5. Molecular formula: C21H28ClNO. Mole weight: 345.91. | |
| Diphenylpyraline | Diphenylpyraline, a piperidine derivative, has been found to be a H1 receptor antagonist that could be probably effective against some allergy acts. Synonyms: AN 1041; AN-1041; AN1041; Diphenylpyraline; Hispril; Belfene; Mepiben; Allergen; Lyssipoll; 4-benzhydryloxy-1-methylpiperidine. Grades: 98%. CAS No. 147-20-6. Molecular formula: C19H23NO. Mole weight: 281.39. | |
| DIPPA hydrochloride | DIPPA hydrochloride is an irreversible and selective antagonist of κ-opioid receptor (KOR). Synonyms: 2-(3,4-Dichlorophenyl)-N-methyl-N-[(1S)-1-(3-isothiocyanatophenyl)-2-(1-pyrrolidinyl)ethyl]acetamide hydrochloride. Grades: ≥99% by HPLC. CAS No. 155512-52-0. Molecular formula: C22H23Cl2N3OS.HCl. Mole weight: 484.87. | |
| Dipraglurant | Dipraglurant is a mGlu5 receptor negative allosteric modulator. It is currently in phase II for the treatment of dyskinesia in Parkinson's disease. Synonyms: ADX-48621; ADX48621; ADX 48621; Dipraglurant. Grades: >98%. CAS No. 872363-17-2. Molecular formula: C16H12FN3. Mole weight: 265.29. | |
| Disopyramide | Disopyramide is a sodium channel blocker that, in rabbit ventricular myocytes, binds and dissociates from open channels more quickly than from resting channels. Formulations containing disopyramide have been used in the treatment of cardiac arrhythmias and hypertrophic cardiomyopathy. Uses: Voltage-gated sodium channel blockers. Synonyms: (±)-Disopyramide; Ritmilen; SC-7031; Dicorantil; Rythmodan; Disopiramida. Grades: ≥98%. CAS No. 3737-9-5. Molecular formula: C21H29N3O. Mole weight: 339.5. | |
| Disopyramide phosphate | Disopyramide phosphate is an oral antiarrhythmic agent for the treatment of cardiac arrhythmias. Disopyramide is a sodium channel blocker and therefore classified as a Class 1a anti-arrhythmic agent. Synonyms: 4-[di(propan-2-yl)amino]-2-phenyl-2-pyridin-2-ylbutanamide;phosphoric acid; Diisopyramide; Norpace; Palpitin; Palpitine; Rhythmodan. Grades: >98%. CAS No. 22059-60-5. Molecular formula: C21H32N3O5P. Mole weight: 437.47. | |
| DJ-V-159 | DJ-V-159 is an agonist of G protein-coupled receptor family C group 6 member A (GPRC6A). Synonyms: N1, N3-Bis (4-Cyano-3- (Trifluoromethyl) Phenyl) Isophthalamide; 1-N,3-N-Bis[4-Cyano-3-(Trifluoromethyl)Phenyl]Benzene-1,3-Dicarboxamide; DJ-V159; BCP30173; DJ-V 159; EX-A3017. Grades: 98%. CAS No. 2253744-53-3. Molecular formula: C24H12F6N4O2. Mole weight: 502.4. | |
| DL-Adrenaline | DL-Adrenaline is a hormone and a neurotransmitter secreted by the medulla of the adrenal glands. Synonyms: DL-Adrenaline; DL Adrenaline; Racepinefrine; Racepinephrine; DL-Epinephrine; DL Epinephrine; (+/-)-Adrenaline; rac Epinephrine. Grades: >98%. CAS No. 329-65-7. Molecular formula: C9H13NO3. Mole weight: 183.2. | |
| DL-AP3 | DL-AP3 has been found to be an inhibitor of mGluR as well as HPSP. Uses: Excitatory amino acid antagonists. Synonyms: DL-2-Amino-3-phosphonopropionic acid. Grades: ≥95% by HPLC. CAS No. 20263-06-3. Molecular formula: C3H8NO5P. Mole weight: 169.07. | |
| DL-AP5 | DL-AP5, an NMDA receptor antagonist, could be used as an anticonvulsant agent. Synonyms: AP-5; AP5; AP 5; DL-2-Amino-5-phosphonopentanoic acid. Grades: ≥98% by HPLC. CAS No. 76326-31-3. Molecular formula: C5H12NO5P. Mole weight: 197.13. | |
| DL-AP5 Sodium salt | The sodium salt form of DL-AP5, which is a potent NMDA antagonist. Synonyms: DL-2-Amino-5-phosphonopentanoic acid sodium salt. Grades: ≥98% by HPLC. CAS No. 1303993-72-7. Molecular formula: C5H11NNaO5P. Mole weight: 219.11. | |
| d[leu4,Lys8]-VP | d[leu4,Lys8]-VP is a selective vasopressin V1B receptor agonist (Ki = 0.16, 64, 100 and 3800 nM for V1B, oxytocin, V2 and V1A receptors, respectively). It exhibits weak antidiuretic, vasopressor and in vitro oxytocic activities. Synonyms: D[Leu4,Lys8]VP; 1-Deamino-4-leu-8-lys-vasopressin; Vasopressin, 1-deamino-leu(4)-lys(8)-. CAS No. 42061-33-6. Molecular formula: C47H67N11O11S2. Mole weight: 1026.2. | |
| DM8966 | DM8966, also known as Vebufloxacin, shows potent antibacterial activity against gram-positive and -negative bacteria. Synonyms: 9-fluoro-5-methyl-6,7-dihydro-8-(4-methyl-1-piperazinyl)-1-oxo-1H,5H-benzo(i,j)quinolizine-2-carboxylic acid; benofloxacin; OPC 7241; OPC-7241; OPC7241. CAS No. 79644-90-9. Molecular formula: C19H22FN3O3. Mole weight: 359.39. | |
| DMAB-anabaseine dihydrochloride | DMAB-anabaseine dihydrochloride is a partial agonist at α7-containing neuronal nicotinic receptors and antagonist at α4β2 and other nicotinic receptors. It potentiated long-term memory in rats. Synonyms: Benzenamine, 4-[(5,6-dihydro[2,3'-bipyridin]-3(4H)-ylidene)methyl]-N,N-dimethyl-, hydrochloride (1:2); 4-[(5,6-Dihydro[2,3'-bipyridin]-3(4H)-ylidene)methyl]-N,N-dimethylbenzenamine dihydrochloride; Benzenamine, 4-[(5,6-dihydro[2,3'-bipyridin]-3(4H)-ylidene)methyl]-N,N-dimethyl-, dihydrochloride; DMAB-anabaseine hydrochloride. Grades: ≥98% by HPLC. CAS No. 154149-38-9. Molecular formula: C19H21N3.2HCl. Mole weight: 364.32. | |
| DMCM hydrochloride | DMCM hydrochloride, a negative allosteric modulator of GABAA receptors, is a benzodiazepine inverse agonist with strong anxiogenic and convulsant properties. Synonyms: 9H-Pyrido[3,4-b]indole-3-carboxylic acid, 4-ethyl-6,7-dimethoxy-, methyl ester, hydrochloride (1:1); 4-Ethyl-6,7-dimethoxy-9H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester hydrochloride; 6,7-Dimethoxy-4-ethyl-β-carboline-3-carboxylic acid methyl ester hydrochloride; Methyl 6,7-dimethoxy-4-ethyl-β-carboline-3-carboxylate hydrochloride. Grades: ≥98% by HPLC. CAS No. 1215833-62-7. Molecular formula: C17H18N2O4.HCl. Mole weight: 350.80. | |
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