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Eumenine mastoparan-OD
Eumenine mastoparan-OD has potent hemolytic activity against ovine erythrocytes at micromolar concentrations. It also exhibits strong antimicrobial activity against the fungi C.albicans and B.cinerea, and weaker activity against the Gram-negative bacterium E.coli and Gram-positive bacterium S.aureus. Synonyms: EMP-OD.
Eumenitin
Eumenitin is a cationic linear alpha-helical antimicrobial peptide that binds preferentially to charged lipid membranes as compared with zwitterionic ones. It exhibits inhibitory activity against both Gram-positive and Gram-negative bacteria, and moderately stimulates degranulation from the rat peritoneal mast cells. Eumenitin does not show hemolytic activity. It may play a role in preventing infection by microorganisms during prey consumption by their larvae. Grade: >97% by HPLC. Molecular formula: C78H137N19O19. Mole weight: 1645.03.
Eurocin
Eurocin acts against a range of Gram-positive human pathogens but not against Gram-negative bacteria.
European bumblebee abaecin
European bumblebee abaecin is a Pro-rich peptide. It is active against B. negaterium (MIC=10 ug/ml), E. coli, and A. tumefaciens (25 ug/ml). The source of European bumblebee abaecin is Bombus pascuorum (Hymenoptera, Apoidea). Grade: >98% by HPLC.
Ewing Tumor EZH2 (666-674)
Ewing Tumor EZH2 (666-674) is a peptide corresponding to residues 666-674 of Ewing Tumor EZH2. EZH2 in Ewing sarcoma cells directly binds to the promoter regions of genes encoding for two key enzymes of GD2 biosynthesis, and EZH2 inhibition enhances expression of these genes. Synonyms: Ewing Tumor Enhancer of Zeste Homolog 2 (666-674).
Exendin-3
Exendin-3 is a bioactive peptide isolated from venoms of the Gila monster lizards, Heloderma horridurn. Synonyms: H-His-Ser-Asp-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2; L-histidyl-L-seryl-L-alpha-aspartyl-glycyl-L-allothreonyl-L-phenylalanyl-L-allothreonyl-L-seryl-L-alpha-aspartyl-L-leucyl-L-seryl-L-lysyl-L-glutaminyl-L-methionyl-L-alpha-glutamyl-L-alpha-glutamyl-L-alpha-glutamyl-L-alanyl-L-valyl-L-arginyl-L-leucyl-L-phenylalanyl-L-isoleucyl-L-alpha-glutamyl-L-tryptophyl-L-leucyl-L-lysyl-L-asparagyl-glycyl-glycyl-L-prolyl-L-seryl-L-seryl-glycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-L-serinamide. Grade: ≥95%. CAS No. 130357-25-4. Molecular formula: C184H282N50O61S. Mole weight: 4202.57.
FA-Ala-Arg-OH is a substrate for human plasma carboxypeptidase N and membrane-bound carboxypeptidase D. Synonyms: Furylacryloylalanylarginine; Furylacryloyl-alanyl-arginine; L-Arginine, N(2)-(N-(3-(2-furanyl)-1-oxo-2-propenyl)-L-alanyl)-. CAS No. 76079-06-6. Molecular formula: C16H23N5O5. Mole weight: 365.38.
Fa-AMP1
Fa-AMP1 is produced by Fagopyrum esculentum. The concentration of peptide required for 50% inhibition (IC50) of the growth of plant pathogenic fungi, and Gram-positive and -negative bacteria is 11 to 36 microg/ml. Mole weight: 3879.
Fa-AMP2
Fa-AMP2 is produced by Fagopyrum esculentum. The concentration of peptide required for 50% inhibition (IC50) of the growth of plant pathogenic fungi, and Gram-positive and -negative bacteria is 11 to 36 microg/ml. Mole weight: 3906.
Fabatin-1
Fabatin-1 is active against both Gram-negative and Gram-positive bacteria, but is inactive against the yeasts Saccharomyces cerevisiae and Candida albicans.
Fabatin-2
Fabatin-2 is active against both Gram-negative and Gram-positive bacteria, but is inactive against the yeasts Saccharomyces cerevisiae and Candida albicans.
FA-Glu-Glu-OH
FA-Glu-Glu-OH is the preferred substrate for carboxypeptidase O in humans and zebrafish. Synonyms: N-[(2E)-3-(2-Furyl)-2-propenoyl]-L-α-glutamyl-L-glutamic acid; L-Glutamic acid, N-[(2E)-3-(2-furanyl)-1-oxo-2-propen-1-yl]-L-α-glutamyl-; (S)-2-((S)-4-carboxy-2-((E)-3-(furan-2-yl)acrylamido)butanamido)pentanedioic acid; FA-EE-OH. Grade: ≥90%. CAS No. 1374423-90-1. Molecular formula: C17H20N2O9. Mole weight: 396.35.
FA-Gly-Abu-NH2
FA-Gly-Abu-NH2 can be used as substrate in a substrate specificity study of thermolysin. Synonyms: 3-(2-Furyl)acryloyl-Gly-Abu-NH2. Grade: ≥ 98%. CAS No. 67607-48-1. Molecular formula: C13H17N3O4. Mole weight: 279.30.
Fa-Gly-OH. Synonyms: (E)-2-(3-(Furan-2-yl)acrylamido)acetic acid; Furanacryloylglycine; Fa Gly OH. Grade: 95%. CAS No. 124882-74-2. Molecular formula: C9H9NO4. Mole weight: 195.17.
FA-Gly-Phe-Leu-OH
FA-Gly-Phe-Leu-OH. CAS No. 390766-88-8. Molecular formula: C24H29N3O6. Mole weight: 455.50.
FALGPA
Falgpa is a type of synthetic compound that has been used in laboratory experiments for various purposes since its discovery in the 1990s. It is a derivative of the naturally occurring chemical, phenylalanine, and has been found to have a variety of biochemical and physiological effects on living organisms. Synonyms: 2-furanacryloyl-leucyl-glycyl-prolyl-alanine; FA-LEU-GLY-PRO-ALA-OH; FALGPA; COLLAGENASE SUBSTRATE II; N-(3-[2-FURYL]ACRYLOYL)-LEU-GLY-PRO-ALA; N-[3-(2-FURYL)ACRYLOYL]-L-LEUCYL-GLYCYL-L-PROLYL-L-ALANINE; clostridiopeptidase; N-(3-(2-FURYL)ACRYLOYL)-L-LEUCYL-GLY. Grade: >95% by HPLC. CAS No. 78832-65-2. Molecular formula: C23H32N4O7. Mole weight: 476.52.
FALL-39, a putative human peptide antibiotic, is cysteine-free and expressed in bone marrow and testis.
Fallaxidin-3.1
Fallaxidin-3.1 was found in Litoria fallax. It has antibacterial activity.
Fallaxidin 3.2
Fallaxidin 3.2 has antibacterial activity. Fallaxidin 3.2 was found in Litoria fallax [Eastern dwarf tree frog].
Fallaxidin 4.1
Fallaxidin 4.1 was found in Litoria fallax. Fallaxidin 4.1 has antibacterial activity against L.lactis (MIC = 12 microM), M.luteus (MIC = 100 microM), S.epidermidis (MIC = 100 microM), and S.uberis (MIC = 50 microM).
Fanconi anemia group M protein (201-214)
Fanconi anemia group M protein (201-214) is a bioactive peptide of Fanconi anemia group M protein. It is believed that FACM in conjunction with other Fanconi anemia- proteins repair DNA at stalled replication forks, and stalled transcription structures called R-loops. Synonyms: Protein FACM (201-214); ATP-dependent RNA helicase FANCM (201-214).
A substrate for a sensitive spectrophotometric assay of serum carboxypeptidase A. Synonyms: N-(3-[2-Furyl]acryloyl)-Phe-Phe; FAPP; Furylacryloyl-Phe-Phe; (S)-2-((S)-2-((E)-3-(furan-2-yl)acrylamido)-3-phenylpropanamido)-3-phenylpropanoic acid. CAS No. 83661-95-4. Molecular formula: C25H24N2O5. Mole weight: 432.47.
FAST kinase domain-containing protein 1 isoform 1 (497-514)
FAST kinase domain-containing protein 1 isoform 1 (497-514) is a peptide derived from FAST kinase domain-containing protein 1 isoform 1. FAST kinase domain-containing protein 1 is involved in the down-regulation of mitochondrial MT-ND3 mRNA levels which leads to decreased respiratory complex I abundance and activity.
FATGIGIITV
FATGIGIITV is a peptide fragment which acts as a superagonist.
F-box protein FBL5 (227-255)
F-box protein FBL5 (227-255) is a peptide corresponding to residues 227-255 of F-box protein FBL5. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination.
FBXO41 protein, partial (284-297)
FBXO41 protein, partial (284-297) is a 14-aa peptide. FBXO41 is a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Synonyms: F-box only protein 41 (284-297).
FeCath
FeCath has antibacterial activity. It is active against E. coli D31, S. enterica serovar Typhimurium (IR715), L. monocytogenes and S. pseudintermedius (clinical isolate). FeCath was found in the bone marrow, Felis catus. Grade: >95% by HPLC.
FFAGLDD amine salt
FFAGLDD amine salt is an MMP9 selective cleavage peptide, which was used for cytosolic delivery of Doxorubi-cin (DOX). CAS No. 2703745-71-3. Molecular formula: C37H52N8O12. Mole weight: 800.85.
FGL, a NCAM (neural cell adhesion molecule) mimetic peptide, binds to the Fibroblast Growth Factor Receptor 1 (FGFR-1) and has been shown to improve normal memory functioning and mitigate certain pathological cognitive impairments. While FGL does not affect basal synaptic transmission, it facilitates both the induction and maintenance of long-term potentiation (LTP). Additionally, FGL influences heterosynaptic plasticity at adjacent lateral perforant path synapses. Synonyms: H-Glu-Val-Tyr-Val-Val-Ala-Glu-Asn-Gln-Gln-Gly-Lys-Ser-Lys-Ala-OH; L-Alanine, L-α-glutamyl-L-valyl-L-tyrosyl-L-valyl-L-valyl-L-alanyl-L-α-glutamyl-L-asparaginyl-L-glutaminyl-L-glutaminylglycyl-L-lysyl-L-seryl-L-lysyl-; L-α-Glutamyl-L-valyl-L-tyrosyl-L-valyl-L-valyl-L-alanyl-L-α-glutamyl-L-asparaginyl-L-glutaminyl-L-glutaminylglycyl-L-lysyl-L-seryl-L-lysyl-L-alanine; FGL; FGL (peptide). Grade: ≥95%. CAS No. 499993-62-3. Molecular formula: C71H116N20O25. Mole weight: 1649.80.
FHV Coat-(35-49)
It is a peptide extracted from the flock house virus (FHV) coat protein and internalized with maximum efficiency into Chinese hamster ovary (CHO-K1), HeLa, and Jurkat cells. Synonyms: H-Arg-Arg-Arg-Arg-Asn-Arg-Thr-Arg-Arg-Asn-Arg-Arg-Arg-Val-Arg-OH; L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-asparagyl-L-arginyl-L-threonyl-L-arginyl-L-arginyl-L-asparagyl-L-arginyl-L-arginyl-L-arginyl-L-valyl-L-arginine. Grade: ≥95%. Molecular formula: C83H162N50O19. Mole weight: 2164.54.
Fibrinogen-Binding Peptide butyl acetate
Fibrinogen-Binding Peptide (designed by the anti-complementarity hypothesis) is a presumptive peptide mimic of the vitronectin binding site on the fibrinogen receptor. It binds to fibrinogen and inhibits platelet adhesion to fibrinogen and platelet aggregation, as well as platelet adhesion to vitronectin. Synonyms: Fibrinogen-Binding Peptide (fb-acetate); H-Glu-His-Ile-Pro-Ala-OH butyl acetate; EHIPA butyl acetate; L-alpha-glutamyl-L-histidyl-L-isoleucyl-L-prolyl-L-alanine butyl acetate. Grade: ≥95%. Molecular formula: C31H51N7O10. Mole weight: 681.80.
Fibrinopeptide B
Fibrinopeptide B. Synonyms: Fibrinopeptide B, human. Grade: >95%. CAS No. 36204-23-6. Molecular formula: C66H93N19O25. Mole weight: 1552.56.
Fibronectin Adhesion-promoting Peptide acetate
It is a heparin-binding amino acid sequence found in the heparin-binding domain at the carboxy-terminal of fibronectin. Synonyms: Heparin Binding Peptide acetate. Molecular formula: C49H78N16O12. Mole weight: 1083.25.
Fibronectin CS1 Peptide acetate
Fibronectin CS1 Peptide lacks a domain containing Arg-Gly-Asp, and it can effectively inhibit tumor metastasis in both spontaneous and experimental metastatic models. Synonyms: H-Glu-Ile-Leu-Asp-Val-Pro-Ser-Thr-OH.CH3CO2H; L-alpha-glutamyl-L-isoleucyl-L-leucyl-L-alpha-aspartyl-L-valyl-L-prolyl-L-seryl-L-threonine acetic acid. Grade: ≥95%. CAS No. 2760881-56-7. Molecular formula: C40H68N8O17. Mole weight: 933.01.
Fibronectin type III domain-containing protein 3B (292-300)
Fibronectin type III domain-containing protein 3B (292-300) is a bioactive peptide of Fibronectin type III domain-containing protein 3B. Fibronectin type III domain-containing protein 3B is a positive regulator of adipogenesis. Synonyms: Factor for adipocyte differentiation 104 (292-300); HCV NS5A-binding protein 37 (292-300).
FITC-εAhx-Gly-Arg-Gly-Asp-Ser-Pro-OH is fluorescent dye-labeled GRGDSP. It can be conjugated to carriers by EDC. Synonyms: FITC-εAhx-GRGDSP; FITC-LC-GRGDSP; N-(6-{[(3',6'-Dihydroxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthen]-5-yl)carbamothioyl]amino}hexanoyl)glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-L-proline. Grade: ≥95%. CAS No. 2022956-44-9. Molecular formula: C49H59N11O16S. Mole weight: 1090.14.
FITC-εAhx-HHV-2 Envelope Glycoprotein G (561-578)
FITC-εAhx-HHV-2 Envelope Glycoprotein G (561-578) is the fluorescent analog of HHV-2 Envelope Glycoprotein G (561-578). Synonyms: FITC-εAhx-Pro-Glu-Glu-Phe-Glu-Gly-Ala-Gly-Asp-Gly-Glu-Pro-Pro-Glu-Asp-Asp-Asp-Ser-OH; 1-(6-{[(3',6'-Dihydroxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthen]-5-yl)carbamothioyl]amino}hexanoyl)-L-prolyl-L-α-glutamyl-L-α-glutamyl-L-phenylalanyl-L-α-glutamylglycyl-L-alanylglycyl-L-alpha-aspartylglycyl-L-α-glutamyl-L-prolyl-L-prolyl-L-α-glutamyl-L-α-aspartyl-L-α-aspartyl-L-α-aspartyl-L-serine. Grade: ≥95%. CAS No. 2022956-64-3. Molecular formula: C104H128N20O44S. Mole weight: 2394.33.
Fitc-FF-FMK
Fitc-FF-FMK is a biotin-labeled cathepsin inhibitor that selectively suppresses cathepsin B and cathepsin L. Synonyms: FITC-Phe-Phe-CH2F; FITC-Phe-Phe-fluoromethyl ketone. Grade: ≥95%. Molecular formula: C40H32FN3O7S. Mole weight: 717.77.
FITC-LC-Antennapedia (43-58) Peptide
It is an antennapedia peptide labeled with fluorescent (FITC). The Antennapedia homeodomain protein of Drosophila has the ability to penetrate biological membranes and the third helix of this protein, residues 43-58, known as penetratin (RQIKIWFQNRRMKWKK-NH2) has the same translocating properties as the entire protein. Synonyms: FITC-LC-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-NH2. Grade: >98%. Molecular formula: C131H189N37O25S2. Mole weight: 2746.31.
FITC-LC-MTS
It is a membrane-translocating sequence (MTS) labeled with FITC, which contains a long chain LC to prevent FITC degradation. Adopting fluorescent techniques, the labeled peptide has been studied for its ability to translocate the cell membrane. Synonyms: FITC-LC-Ala-Ala-Val-Leu-Leu-Pro-Val-Leu-Leu-Ala-Ala-Pro-NH2. Grade: >98%.
FITC-LC-TAT (47-57)
This fluorescent (FITC)-labeled TAT peptide contains a long chain (LC) to prevent FITC from degradation. Abs/Em = 493/522 nm. TAT is the most characteristic fragment of HIV trans-activator protein (TAT). The arginine-rich TAT peptide penetrates the plasma membrane directly rather than through endocytosis. Synonyms: FITC-LC-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-NH2. Grade: >95%.
FITC-YVADAPK(Dnp) is a specific FRET substrate used to measure the activity of caspase-1 and caspase-1-like enzymes. Cleavage of FITC-YVADAPK(Dnp) at the P1 Asp residue results in a continuous fluorescent assay. It is useful both in FACS and fluorescence microscopy experiments. Caspase-3 is only weakly active using this substrate. The cleavage product FITC-YVAD can be used as a reference substance. Synonyms: N-[(3',6'-Dihydroxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthen]-6-yl)carbamothioyl]-L-tyrosyl-L-valyl-L-alanyl-L-α-aspartyl-L-alanyl-L-prolyl-N6-(2,4-dinitrophenyl)-L-lysine; L-Lysine, N-[[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-6-yl)amino]thioxomethyl]-L-tyrosyl-L-valyl-L-alanyl-L-α-aspartyl-L-alanyl-L-prolyl-N6-(2,4-dinitrophenyl)-. Grade: ≥90% by HPLC. CAS No. 1926163-32-7. Molecular formula: C62H67N11O20S. Mole weight: 1318.34.
FK-13
FK-13 is a peptide by synthetic construct. It has antibacterial and anticancer activity. Synonyms: CHEMBL1275639; FK-13; H-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-OH. Grade: >96% by HPLC. Molecular formula: C80H135N25O17. Mole weight: 1719.1.
Flagelin 22
Flagelin 22 is a fragment of bacterial flagellin, which is an effective elicitor in both plants and algae. Synonyms: Flagellin 22; L-Alanine, L-glutaminyl-L-arginyl-L-leucyl-L-seryl-L-threonylglycyl-L-seryl-L-arginyl-L-isoleucyl-L-asparaginyl-L-seryl-L-alanyl-L-lysyl-L-α-aspartyl-L-α-aspartyl-L-alanyl-L-alanylglycyl-L-leucyl-L-glutaminyl-L-isoleucyl-; Gln-Arg-Leu-Ser-Thr-Gly-Ser-Arg-Ile-Asn-Ser-Ala-Lys-Asp-Asp-Ala-Ala-Gly-Leu-Gln-Ile-Ala. Grade: ≥95%. CAS No. 304642-91-9. Molecular formula: C93H162N32O34. Mole weight: 2272.48.
FliC, Serotype a (427-441), S.paratyphi A
It is a 427-441 amino acid fragment belonging to FliC, Serotype a of the S. FliC epitope. Synonyms: Val-Gln-Asn-Arg-Phe-Asn-Ser-Ala-Ile-Thr-Asn-Leu-Gly-Asn-Thr; L-valyl-L-glutaminyl-L-asparaginyl-L-arginyl-L-phenylalanyl-L-asparaginyl-L-seryl-L-alanyl-L-isoleucyl-L-threonyl-L-asparaginyl-L-leucylglycyl-L-asparaginyl-L-threonine. Grade: ≥95%. CAS No. 857678-38-7. Molecular formula: C69H113N23O24. Mole weight: 1648.78.
Fluorescein-6-carbonyl-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone is a cell-permeable and non-toxic inhibitor that binds irreversibly to activated caspase-3 in apoptotic cells. Synonyms: 6-FAM-D(OMe)E(OMe)VD(OMe)-FMK; L-Valinamide, N-[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-6-yl)carbonyl]-L-α-aspartyl-L-α-glutamyl-N-[1-(2-fluoroacetyl)-3-methoxy-3-oxopropyl]-, 1,2-dimethyl ester; Methyl (8S,11S,14S)-14-{[(3',6'-dihydroxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthen]-6-yl)carbonyl]amino}-5-(fluoroacetyl)-8-isopropyl-11-(3-methoxy-3-oxopropyl)-3,7,10,13-tetraoxo-2-oxa-6,9,12-triazahexadecan-16-oate. Grade: ≥95%. CAS No. 1926163-65-6. Molecular formula: C43H45FN4O16. Mole weight: 892.83.
Fluorescein-6-carbonyl-Tyr-Val-Ala-DL-Asp(OMe)-fluoromethylketone is an inhibitor of caspase-1. Synonyms: 6-FAM-YVAD(OMe)-FMK; L-Alaninamide, N-[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-6-yl)carbonyl]-L-tyrosyl-L-valyl-N-[1-(2-fluoroacetyl)-3-methoxy-3-oxopropyl]-; N-[(3',6'-Dihydroxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthen]-6-yl)carbonyl]-L-tyrosyl-L-valyl-N-(5-fluoro-1-methoxy-1,4-dioxo-3-pentanyl)-L-alaninamide. Grade: ≥90%. CAS No. 1926163-69-0. Molecular formula: C44H43FN4O13. Mole weight: 854.84.
Fluorogenic Human CMV Protease Substrate
Fluorogenic Human CMV Protease Substrate, the FRET substrate, is used to develop a fluorescence-based detection method for human cytomegalovirus proteinase. It specifically cleaves on the Ala-Ser bond, thereby removing the C-terminal peptide-Edans fragment from the proximity quenching effect of DABCYL groups. This represents the first fluorescence-based assay of the herpes virus protease and allows characterization of potential inhibitors. Synonyms: DABCYL-Arg-Gly-Val-Val-Asn-Ala-Ser-Ser-Arg-Leu-Ala-EDANS; N2-[4-[2-[4-(Dimethylamino)phenyl]diazenyl]benzoyl]-L-arginylglycyl-L-valyl-L-valyl-L-asparaginyl-L-alanyl-L-seryl-L-seryl-L-arginyl-L-leucyl-N-[2-[(5-sulfo-1-naphthalenyl)amino]ethyl]-L-alaninamide. Grade: 95%. CAS No. 163265-38-1. Molecular formula: C73H109N23O18S. Mole weight: 1628.85.