BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Ethyl triphenylphosphoranylidene acetate | Ethyl triphenylphosphoranylidene acetate is a Horner-Wittig reagent generally used in Horner-Wadsworth-Emmons (HWE) reaction. It may act as an inhibitor of cholinesterase that inhibits AChE and BChE. Synonyms: (Carbethoxymethylene) triphenylphosphorane; Triphenylcarbethoxy methyl enephosphorane; Ethyl 2-(triphenylphosphoranylidene)acetate. Grades: ≥ 95 %. CAS No. 1099-45-2. Molecular formula: C22H21O2P. Mole weight: 348.37. |  |
| ethynodiol diacetate | Ethynodiol diacetate is one of the first synthetic progestogens used in contraceptive pills.Relative to other 19-nortestosterone derivatives, it has relatively little or no potency as an androgen and also unlike most progestins in general, has significant estrogenic effects. Synonyms: 8080 CB. Grades: >98%. CAS No. 297-76-7. Molecular formula: C24H32O4. Mole weight: 384.51. | |
| Eticlopride | Eticlopride is a selective dopamine D2 antagonist. It was initially developed as a potential antipsychotic agent. Now Eticlopride is primarily used in pharmacological research. Uses: Antipsychotic agent. Synonyms: FLB 131; FLB131; FLB-131; Eticlopride; 5-chloro-3-ethyl-N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-2-hydroxy-6-methoxybenzamide. Grades: 98%. CAS No. 84226-12-0. Molecular formula: C17H25ClN2O3. Mole weight: 340.85. | |
| Eticlopride hydrochloride | Eticlopride hydrochloride is a selective dopamine D2/D3 receptor antagonist (Ki = 0.50 and 0.16 nM, respectively). Uses: Antipsychotic. Synonyms: FLB 131; 3-Chloro-5-ethyl-N-[[(2S)-1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxy-benzamide hydrochloride. Grades: ≥99% by HPLC. CAS No. 97612-24-3. Molecular formula: C17H25ClN2O3.HCl. Mole weight: 377.31. | |
| Etifoxine Hydrochloride | Etifoxine Hydrochloride is Potentiator of GABAA receptor with anxiolytic and anticonvulsant activity. Uses: Psychotropic agent with anxiolytic and anticonvulsant activity. Synonyms: 6-Chloro-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-amine Hydrochloride; 2-Ethylamino-6-chloro-4-methyl-4-phenyl-4H-3,1-benzoxazine Hydrochloride. Grades: ≥98%. CAS No. 56776-32-0. Molecular formula: C17H18Cl2N2O. Mole weight: 337.24. | |
| Etiguanfacine | Etiguanfacine is a α2-Adreno Receptor agonist using for the treatment of ADHD (Attention deficit hyperactivity disorder). Uses: Attention deficit hyperactivity disorder. Synonyms: SSP-1871; SSP1871; SSP 1871 Etiguanfacine;ethyl N-{[2- (2, 6-dichlorophenyl) acetyl]carbamimidoyl}carbamate. Grades: 98%. CAS No. 1346686-31-4. Molecular formula: C12H13Cl2N3O3. Mole weight: 318.16. | |
| Etisazole | Etoxazole is a narrow spectrum systemic acaricide used to combat spider mites. Uses: Antifungal agent. Synonyms: Etisazolum; Etisazolum [INN-Latin]; Netrosylla; Bay VA 9387; BAY-VA 9387; Ectimar; EINECS 231-739-9; N-ethyl-1,2-Benzisothiazol-3-amine. Grades: 98%. CAS No. 7716-60-1. Molecular formula: C9H10N2S. Mole weight: 178.25. | |
| Etomoxir | An inhibitor of carnitine palmitoyltransferase A (CPT1), which is required for the oexidation of long-chain acyl CoA esters. A strong inhibitor of mitochondrial CPT1 and is a candidate as an anti-diabetic drug. Uses: Hypoglycemic agents. Synonyms: Etomoxir; B 807-54; B807-54; B-807-54; B 80754; B80754; B-80754; (R)-(+)-Etomoxir. Grades: >98%. CAS No. 124083-20-1. Molecular formula: C17H23ClO4. Mole weight: 326.82. | |
| ETP 45658 | ETP 45658 is a PI 3-kinase inhibitor (IC50 = 22, 30, 129 and 710 nM for PI 3-Kα, PI 3-Kδ, PI 3-Kβ and PI 3-Kγ, respectively), and it also inhibits DNA-PK and mTOR (IC50 = 70.6 and 152 nM, respectively). ETP 45658 causes blockade of proliferation in multiple cancer cell lines in vitro and a decrease of Akt phosphorylation levels in vivo. Synonyms: ETP-45658; ETP 45658; ETP45658; 3-[1-Methyl-4-(4-morpholinyl)-1H-pyrazolo[3,4-d]pyrimidin-6-ylphenol. Grades: ≥98% by HPLC. CAS No. 1198357-79-7. Molecular formula: C16H17N5O2. Mole weight: 311.34. | |
| ETP-46464 | ETP-46464 is a cell-permeable quinoline-containing heterotricyclic compound that acts as a potent inhibitor against mTOR, ATR, DNA-PK, PI 3-Kα, and ATM (IC50= 0.6, 14, 36, 170, and 545 nM, respectively). Synonyms: ETP46464; ETP 46464; ETP-46464. Grades: >98%. CAS No. 1345675-02-6. Molecular formula: C30H22N4O2. Mole weight: 470.52. | |
| Etripamil | Etripamil, a benzoates derivative, has been found to be a calcium channel antagonist that could be used against hypertension and arrhythmic. It is currently under Phase II trail against paroxysmal supraventricular tachycardia. Synonyms: (-)-MSP-2017; MSP-2017; MSP 2017; MSP2017; MSP-2017A; MSP-2017B; Etripamil; UNII-S82A18Y42P; MSP-2017; (-)-MSP-2017; S82A18Y42P; Etripamil [USAN:INN]; methyl 3-[2-[[(4S)-4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl]-methylamino]ethyl]benzoate. Grades: 98%. CAS No. 1593673-23-4. Molecular formula: C27H36N2O4. Mole weight: 452.60. | |
| Etybenzatropine | Etybenzatropine is an anticholinergic/antihistamine. It is used as an antiparkinsonian agent. It may act as a dopamine reuptake inhibitor. Uses: Etybenzatropine is used as an antiparkinsonian agent. Synonyms: Ponalide;UK-738; UK738; UK 738; VK-738; VK 738; VK738; (1R,5S)-3-benzhydryloxy-8-ethyl-8-azabicyclo[3.2.1]octane;3-alpha-(Diphenylmethoxy)-8-ethyl-1alphaH,5alphaH-nortropane;3-(Diphenylmethoxy)-8-ethylnortropane;N-Ethylnortropine benzhydryl ether;Nortropane, 3-(diphenylmethoxy)-8-ethyl-. Grades: 95%. CAS No. 524-83-4. Molecular formula: C22H27NO. Mole weight: 321.46. | |
| Evenamide | Evenamide is a selective voltage-gated sodium and?/or calcium channel modulator, including subtypes Nav1.3, Nav1.7, and Nav1.8. It may be potentia useful in preventing, alleviating and curing a wide range of pathologies, including neurol., cognitive, psychiatric, inflammatory, urogenital and gastrointestinal diseases. It has shown efficacy in animal models of psychosis, mania, depression, and aggression. It was under development by Newron Pharmaceuticals as an add-on therapy for the treatment of schizophrenia. It is in phase II clinical trials. Uses: Evenamide may be potentia useful in preventing, alleviating and curing a wide range of pathologies, including neurol., cognitive, psychiatric, inflammatory, urogenital and gastrointestinal diseases. it is used as an add-on therapy for the treatment of schizophrenia. Synonyms: 2-[2-(3-Butoxyphenyl)ethylamino]-N,N-dimethylacetamide; NW-3509; NW 3509; NW3509; NW-3509A; Evenamide. Grades: >98%. CAS No. 1092977-61-1. Molecular formula: C16H26N2O2. Mole weight: 278.40. | |
| Evernic Acid | Evernic acid is a secondary metabolite produced by some species of lichen. It is an inhibitor of two key plasmodial FAS-II enzymes PfFabZ and PfFabI (IC50 = 10.7 and 36.1 μM, respectively). Synonyms: NSC 81164; 2-hydroxy-4-(2-hydroxy-4-methoxy-6-methylbenzoyl)oxy-6-methylbenzoic acid. Grades: ≥98%. CAS No. 537-09-7. Molecular formula: C17H16O7. Mole weight: 332.3. | |
| Evifacotrep | Evifacotrep is a short transient receptor potential channel 5 (TRPC5) antagonist. Synonyms: 4-chloro-5-{4-[4-fluoro-2-(trifluoromethyl)phenoxy]-5,8-dihydropyrido[3,4-d]pyrimidin-7(6H)-yl}pyridazin-3(2H)-one. CAS No. 2413739-88-3. Molecular formula: C18H12ClF4N5O2. Mole weight: 441.77. | |
| Evocalcet | Evocalcet is a calcium-sensing receptor agonist under the development of Kyowa Hakko Kirin. Phase III clinical trials for Secondary hyperparathyroidism are on-going in Japan. Uses: Secondary hyperparathyroidism. Synonyms: MT-4580; MT 4580; MT4580; KHK-7580; KHK7580; KHK 7580; Evocalcet;2-(4-((S)-3-(((R)-1-(naphthalen-1-yl)ethyl)amino)pyrrolidin-1-yl)phenyl)acetic acid. Grades: 98%. CAS No. 870964-67-3. Molecular formula: C24H26N2O2. Mole weight: 374.48. | |
| Evogliptin | This active molecular is a selective dipeptidyl peptidase 4 (DPP4) inhibitor under the development of Dong-A. Evogliptin improves insulin resistance and delays the onset of diabetes. Evogliptin monotherapy improved HbA1c, fasting plasma glucose level, OGTT results and β-cell function. In Sep 1st 2016, preclinical trials in Type-2 diabetes mellitus (Combination therapy) in Russia was on-going. In Sep 12th 2016, Phase-I clinical trials in non-alcoholic steatohepatitis (Combination therapy) in USA was on-going. Uses: Type-2 diabetes mellitus. Synonyms: (3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-[(2-methylpropan-2-yl)oxymethyl]piperazin-2-one;CHEMBL1779710; UNII-09118300L7; DA-1229; DA 1229; DA1229; 1222102-29-5; Evogliptin [INN];1246960-27-9 (HCl). Grades: 98%. CAS No. 1222102-29-5. Molecular formula: C19H26F3N3O3. Mole weight: 401.43. | |
| EVP-6124 | EVP-6124 is a novel partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs). It shows selectivity for α7 nAChRs and did not activate or inhibit heteromeric α4β2 nAChRs and improves memory performance by potentiating the acetylcholine response of α7 nicotinic acetylcholine receptors. Synonyms: EVP-6124; EVP6124; EVP 6124; MT-4666; MT4666; MT 4666; Encenicline. Grades: >98%. CAS No. 550999-75-2. Molecular formula: C16H17ClN2OS. Mole weight: 320.84. | |
| EX229 | EX229 (compound 991), also known as AMPK Activator 991, is a potent AMPK activator that displays 5-10-fold more potent than A769662 in activating AMPK. Synonyms: Compound 991; AMPK Activator 991; 5-[[6-chloro-5-(1-methylindol-5-yl)-1H-benzimidazol-2-yl]oxy]-2-methylbenzoic acid. Grades: ≥98%. CAS No. 1219739-36-2. Molecular formula: C24H18ClN3O3. Mole weight: 431.87. | |
| EX-527 | EX 527 is a potent and selective SIRT1 inhibitor with IC50 of 38 nM, exhibits >200-fold selectivity against SIRT2 and SIRT3. Synonyms: SEN0014196; EX-527; EX-527; EX-527; Selisistat. Grades: >98%. CAS No. 49843-98-3. Molecular formula: C13H13ClN2O. Mole weight: 248.71. | |
| EX-527 R-enantiomer | EX-527 R-enantiomer is the R-enantiomer of EX-527, which is a potent and selective SIRT1 inhibitor and with no inhibition on SIRT3 and SIRT3. It is a negative control of the active form EX-527 S-enantiomer. Synonyms: Selisistat R-enantiomer; (R)-Selisistat; EX-527(R); EX 527(R); EX527(R). Grades: >98%. CAS No. 848193-69-1. Molecular formula: C13H13ClN2O. Mole weight: 248.71. | |
| EX-527 S-enantiomer | EX-527 S-enantiomer is the S-enantiomer of EX-527, which is a potent and selective SIRT1 inhibitor and with no inhibition on SIRT3 and SIRT3. Synonyms: Selisistat S-enantiomer; EX-527(S); (S)-Selisistat; EX 527(S); EX527(S); EX-527S; EX527S. Grades: >98%. CAS No. 848193-68-0. Molecular formula: C13H13ClN2O. Mole weight: 248.71. | |
| Exalamide | Exalamide is a derivative of salicylamide used as an antifungal. Uses: Used as an antifungal. Synonyms: 2-(Hexyloxy)benzamide; 2-hexoxybenzamide. Grades: ≥95%. CAS No. 53370-90-4. Molecular formula: C13H19NO2. Mole weight: 221.3. | |
| exo-IWR 1 | exo-IWR 1, the enantiomer of IWR-1 and the diastereomer of IWR-1-endo, is a potent SAR anticancer Wnt response inhibitor, which is a kind of small secreted proteins and are active in tissue homeostasis, tumorigenesis and embryonic development. It shows decreased activity against the Wnt/β-catenin pathway. It may be an ideal control for tests involving the active form, IWR-1-endo. It may be used in the treatment of some diseases and conditions such as degenerative diseases, cancers, osteopetrosis and type II diabetes. Synonyms: rel-4-[(3aR,4R,7S,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide; 4-[(3aR,4R,7S,7aS-rel)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide. Grades: ≥99% by HPLC. CAS No. 1127442-87-8. Molecular formula: C25H19N3O3. Mole weight: 409.44. | |
| (E,Z)-2-propyl-2-Pentenoic Acid | (E,Z)-2-propyl-2-Pentenoic acid is a bioactive metabolite of valproic acid that exhibits the same profile and potency of anticonvulsant activity in animal models as its parent compound without any observed teratogenicity and hepatotoxicity. Uses: Teratogens. Synonyms: 2-propyl-2-pentenoate; 2-propylpenten-2-oic acid; 2-ene-VPA; 2-en-valproic acid. Grades: ≥98%. CAS No. 60218-41-9. Molecular formula: C8H14O2. Mole weight: 142.2. | |
| FAAH inhibitor 1 | Time-dependent preincubation study of FAAH inhibitor 1 was consistent with it being a reversible inhibitor. Activity-based protein-profiling (ABPP) evaluation of FAAH inhibitors 1 in rat tissues revealed that it had exceptional selectivity and no off-target activity with respect to other serine hydrolases. Molecular shape overlay of FAAH inhibitor 1 with a known FAAH inhibitor indicated that these compounds might act as transitionstate analogues, forming putative hydrogen bonds with catalytic residues and mimicking the charge distribution of the tetrahedral transition state. FAAH inhibitors 1 was exclusively specific against FAAH in rat brain and had no missing protein bands in all the other tissues that were tested. Synonyms: FAAH inhibitor 1. Grades: >98%. CAS No. 326866-17-5. Molecular formula: C24H23N3O3S3. Mole weight: 497.65. | |
| Facinicline | Facinicline is a partial agonist of the nicotinic alpha-7 (α7) receptor. It is used for the oral treatment of Alzheimer's. It was being co-developed by Roche and was in clinic phase 2 trials with no progress. Uses: Facinicline is used for the oral treatment of alzheimer's. Synonyms: Facinicline; RG-3487; MEM-3454; R-3487; RO-5313534; RG3487; MEM3454; R-487; RO5313534; RG 3487; MEM 3454; R 3487; RO 5313534; (S)-N-(quinuclidin-3-yl)-1H-indazole-3-carboxamide;N-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-1H-indazole-3-carboxamide. Grades: 98%. CAS No. 677306-35-3. Molecular formula: C15H18N4O. Mole weight: 270.34. | |
| Faldaprevir | Faldaprevir, also called as BI 201335, is a potent, once-daily (QD), hepatitis C virus (HCV) NS3/4A protease inhibitor with the potential to treat HCV infection. Faldaprevir (BI 201335) is undergoing testing in a Phase II clinical study in Hepatitis C released by Trek Therapeutics. Synonyms: Faldaprevir; BI-201335; BI 201335; BI201335; (1S,2R)-1-[[(2S,4R)-4-[8-bromo-7-methoxy-2-[2-(2-methylpropanoylamino)-1,3-thiazol-4-yl]quinolin-4-yl]oxy-1-[(2S)-2-(cyclopentyloxycarbonylamino)-3,3-dimethylbutanoyl]pyrrolidine-2-carbonyl]amino]-2-ethenylcyclopropane-1-carboxylic acid; BI 201335; BI-201335; BI201335; faldaprevir; N-((cyclopentyloxy)carbonyl)-3-methylvalyl-4-((8-bromo-7-methoxy-2-(2-((2-methylpropanoyl)amino)-1,3-thiazol-4-yl)quinolin-4-yl)oxy)-N-(1-carboxy-2-ethenylcyclopropyl)prolinamide. Grades: ≥98% (HPLC). CAS No. 801283-95-4. Molecular formula: C40H49BrN6O9S. Mole weight: 869.84. | |
| Falecalcitriol | Falecalcitriol is an analog of calcitriol. It has a higher potency both in vivo and in vitro systems, and longer duration of action in vivo. Uses: Dermatologic agents. Synonyms: Ro 23-4194; Ro-23-4194; Ro23-4194; ST 630; ST-630; ST630; Flocalcitriol; Hornel, Fulstan; Falecalcitriol. Grades: >98%. CAS No. 83805-11-2. Molecular formula: C27H38F6O3. Mole weight: 524.58. | |
| Falintolol, (Z)- | Falintolol, (Z)- is a novel β-adrenergic antagonist. Synonyms: 1-(tert-butylamino)-3-[(Z)-1-cyclopropylethylideneamino]oxypropan-2-ol. CAS No. 106401-52-9. Molecular formula: C12H24N2O2. Mole weight: 228.33. | |
| Falnidamol | Falnidamol, also known as BIBX 1382, is a pyrimido-pyrimidine with antitumor activity. BIBX 1382 inhibits the intracellular tyrosine kinase domain of the Epidermal Growth Factor Receptor (EGFR) thus specifically reversing the aberrant enzymatic activity from overexpressed and constitutively activated EGFR, and subsequently inhibiting cell proliferation and inducing cell differentiation. Synonyms: BIBX 1382; BIBX1382; BIBX-1382; BIBX 1382BS; BIBX1382BS; BIBX-1382BS; Falnidamol. CAS No. 196612-93-8. Molecular formula: C18H19ClFN7. Mole weight: 387.847. | |
| Famotine hydrochloride | Famotine hydrochloride is a histamine H2 receptor antagonist. lt has no effect on the cytochrome P450 enzyme system, and does not appear to interact with other drugs. It inhibits stomach acid production and is used for the treatment of peptic ulcer disease and gastroesophageal reflux disease. Uses: Famotine hydrochloride is used for the treatment of peptic ulcer disease and gastroesophageal reflux disease. Synonyms: Famotine hydrochloride; UK-2054; UNII-7L9H348XUO; Famotine HCl; Famotine hydrochloride;1-((p-Chlorophenoxy)methyl)-3,4-dihydroisoquinoline hydrochloride;1-[(4-Chlorophenoxy)methyl]-3,4-dihydroisoquinoline hydrochloride. Grades: >98 %. CAS No. 10500-82-0. Molecular formula: C16H15Cl2NO. Mole weight: 308.20. | |
| Fananserin | Fananserin is a 5-HT2A receptor and a dopamine D4 receptor antagonist (Ki = 0.26, 2.93, 25, 38, 70 and 726 nM for 5-HT2A, D4, H1, α1, 5-HT1A and D2 receptors, respectively). Fananserin inhibits 5-HT-induced inositol phosphate formation in vitro (IC50 = 7.76 nM), and antagonizes mescaline-induced head twitches in vivo. Synonyms: Fananserin; RP 62203; RP-62203; RP62203; 2-[3-[4-(4-Fluorophenyl)-1-piperazinyl]propyl]-2H-naphthyl[1,8-cd]isothiazole-1,1-dioxide. Grades: ≥99% by HPLC. CAS No. 127625-29-0. Molecular formula: C23H24FN3O2S. Mole weight: 425.52. | |
| Fandosentan potassium | Fandosentan potassium is an endothelin A antagonist developed for the treatment of pulmonary hypertension. Synonyms: potassium;4-(7-ethyl-1,3-benzodioxol-5-yl)-1,1-dioxo-2-[2-(trifluoromethyl)phenyl]-1$l^{6},2-benzothiazine-3-carboxylate; CI-1034; CI1034; Fandosentan potassium; CI 1034; UNII-14U0D2SA4K; Fandosentan potassium [USAN]; PD 180988; PD 180988-0016; PD-180988. Grades: >98%. CAS No. 221246-12-4. Molecular formula: C25H17F3NO6S. K. Mole weight: 555.56. | |
| Fantofarone | Fantofarone is a highly potent and selective inhibitor of calcium channel. Uses: Enzyme inhibitors. Synonyms: SR 33557; 3,4-dimethoxy-N-methyl-N-[3-[4-[[2-(1-methylethyl)-1-indolizinyl]sulfonyl]phenoxy]propyl]-benzeneethanamine. Grades: ≥98%. CAS No. 114432-13-2. Molecular formula: C31H38N2O5S. Mole weight: 550.7. | |
| Farampator | Farampator, also called as CX-691 or Org24448, is an AMPA receptor positive allosteric modulator and glycine reuptake inhibitor potentially for the treatment of schizophrenia. Synonyms: 2,1,3-benzoxadiazol-5-yl(piperidin-1-yl)methanone; 1-(benzofurazan-5-ylcarbonyl)piperidine; 5-(1-piperidinylcarbonyl)-2,1,3-benzoxadiazole ;farampator; Org-24448; CX-691; Org 24448; CX 691; Org24448; CX691. CAS No. 211735-76-1. Molecular formula: C12H13N3O2. Mole weight: 231.25. | |
| Farnesyl Pyrophosphate ammonium salt | Cas No. 116057-57-9. | |
| Faropenem daloxate | Faropenem daloxate is useful for penem and antibiotics. Faropenem medoxomil has excellent in vitro activity against Streptococcus pneumoniae, Haemophilus influenzae and other key pathogens implicated in acute bacterial rhinosinusitis. Clinical studies have demonstrated that, in the treatment of acute bacterial rhinosinusitis in adults, 7 days of treatment with faropenem medoxomil is as clinically and bacteriologically effective as 10 days of treatment with cefuroxime axetil. One study showed faropenem medoxomil to be superior to cefuroxime axetil. Overall, the safety profile of faropenem medoxomil is similar to that of most comparators. Synonyms: Faropenem medoxil. Grades: >98%. CAS No. 141702-36-5. Molecular formula: C17H19NO8S. Mole weight: 397.4. | |
| Fascaplysin chloride | Fascaplysin is a cell-permeable red pigment that acts as an inhibitor of cyclin D kinase 4/cyclin D1 (IC50 = 0.35 μM). It is significantly less selective for Cdk6/cyclin D1 (IC50 = 3.4 μM) and does not inhibit other Cdks and tyrosine kinases. Synonyms: NSC 622398. Grades: ≥95%. CAS No. 114719-57-2. Molecular formula: C18H11N2O·Cl. Mole weight: 306.8. | |
| FAS-IN-1 | FAS-IN-1, a diazaspiro derivative, has been found to be a fatty acid synthase inhibitor that probably have potential biological usage in anticancer study. Uses: Fas-in-1 has been found to be a fatty acid synthase inhibitor that probably have potential biological usage in anticancer study. Synonyms: FAS-IN-1; FAS IN 1; CHEMBL2147032; SCHEMBL4541971; OGGOWHOQMIINAZ-UHFFFAOYSA-N; BDBM50391837; BDBM 50391837; BDBM-50391837; CS 3932; CS3932; CS-3932. Grades: 98%. CAS No. 1375105-96-6. Molecular formula: C26H27N3O4S. Mole weight: 477.58. | |
| Fasitibant chloride hydrochloride | Fasitibant chloride is a selective nonpeptide kinin B2 receptor antagonist. Phase II clinical trials for the treatment of Osteoarthritis were discontinued. Uses: Osteoarthritis. Synonyms: MEN 16132; MEN16132; MEN-16132; (S) -4-amino-5- (4- (4- ( (2, 4-dichloro-3- ( ( (2, 4-dimethylquinolin-8-yl) oxy) methyl) phenyl) sulfonamido) tetrahydro-2H-pyran-4-carbonyl) piperazin-1-yl) -N, N, N-trimethyl-5-oxopentan-1-aminium chloride hydrochloride;1157852-02-2(Fasitibant chloride). Grades: 98%. CAS No. 869880-33-1. Molecular formula: C36H50Cl4N6O6S. Mole weight: 836.71. | |
| Fasnall benzenesulfonate | Fasnall is an inhibitor of fatty acid synthase (FAS) with an IC50 value of 3.71 μM for the human recombinant enzyme. Synonyms: 5,6-Dimethyl-N-[1-(phenylmethyl)-3-pyrrolidinyl]thieno[2,3-d]pyrimidin-4-amine benzenesulfonate; N-(1-Benzylpyrrolidin-3-yl)-5,6-dimethylthieno[2,3-d] pyrimidin-4-amine benzenesulfonate. Grades: ≥98%. CAS No. 2187367-11-7. Molecular formula: C19H22N4S·C6H6O3S. Mole weight: 496.6. | |
| Fasobegron | Fasobegron acts a β3-adrenoreceptor agonist. Synonyms: [1,1'-Biphenyl]-4-carboxylic acid, 4'-[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]aMino]ethyl]-3-Methoxy-;4-[4-[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]ethyl]phenyl]-2-methoxybenzoic acid;(R)-4'-(2-((2-(3-chlorophenyl)-2-hydroxyethyl)amino)ethyl). Grades: 98%. CAS No. 643094-49-9. Molecular formula: C24H24ClNO4. Mole weight: 425.91. | |
| Fasudil | Fasudil is a potent and selective Rho-kinase (ROCK) inhibitor and vasodilator. ROCK is an enzyme that participates in vasoconstriction and vascular remodeling. Fasudil is used for the treatment of cerebral vasospasm and has the potential to treat pulmonary hypertension as well as certain memory loss. Uses: Protein kinase inhibitors. Synonyms: Fasudil; AT 877; AT-877; AT877; HA 1077; HA-1077; HA1077; 5-(1,4-diazepan-1-ylsulfonyl)isoquinoline. Grades: >98%. CAS No. 103745-39-7. Molecular formula: C14H17N3O2S. Mole weight: 291.369. | |
| FAUC-365 | FAUC-365 is a selective antagonist of dopamine D3 receptor with a Ki of 0.5 nM over dopamine D1/D2L/D2S/D4 receptors (Kis = 8.8, 3.6, 2.6, and 0.34 μM, respectively) as well as 5-HT1A and 5-HT2 (Kis = 0.36 and 2 μM, respectively). Uses: Dopamine antagonists. Synonyms: N-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butyl]-benzo[b]thiophene-2-carboxamide. Grades: ≥98%. CAS No. 474432-66-1. Molecular formula: C23H25Cl2N3OS. Mole weight: 462.4. | |
| FC 99 hydrochloride | FC 99 hydrochloride is an inhibitor of TLR3 expression and suppresses inflammatory responses induced by a synthetic dsRNA (poly(I:C)) and by exogenous IFN-α via IRF3. It inhibits the phosphorylation levels of ERK, JNK, and p38 in varying degrees without altering the total protein. Synonyms: FC 99 hydrochloride; FC99 hydrochloride; FC-99 hydrochloride. Grades: 98%. CAS No. 2734014-73-2. Molecular formula: C15H18N2O.xHCl. Mole weight: 242.32 (free base). | |
| FDL169 | FDL169 is a CFTR corrector (cystic fibrosis transmembrane conductance corrector) that is extracted from patent US20140274933. FDL169 is designed to fix and restore the function of the defective CFTR protein. Synonyms: CFTR corrector 2. Grades: ≥98%. CAS No. 1628416-28-3. Molecular formula: C27H23FN4O4. Mole weight: 486.49. | |
| Febantel | Febantel is an anthelmintic for veterinary use on dogs, cats, cattle, sheep, goats, pig and poultry against roundworms and tapeworms, which is a veteran anthelmintic compound belonging to the chemical class of the benzimidazoles. It is transformed into fenbendazole in the stomach and the intestine of the host, shortly after ingestion. Synonyms: Febantel; Rintal; Bay Vh 5757; Febantelum [INN-Latin]; BAY Vh5757; Febantelum; Combotel; Oratel; Negabot Plus; Paste; Rintal (TN); Febantel (USAN/INN). Grades: >98%. CAS No. 58306-30-2. Molecular formula: C20H22N4O6S. Mole weight: 446.48. | |
| Fedotozine tartrate | Fedotozine tartrate is a kappa(1a) opioid receptor agonist. Synonyms: (2S,3S)-2,3-dihydroxybutanedioic acid;(2R)-N,N-dimethyl-2-phenyl-1-[(3,4,5-trimethoxyphenyl)methoxy]butan-2-amine. Grades: 99%. CAS No. 133267-27-3. Molecular formula: C22H31NO4.C4H6O6. Mole weight: 523.57. | |
| Fedovapagon | Fedovapagon is a potent, nonpeptidic vasopressin V2 receptor agonists (EC50 of 24 nM), demonstrated positive anti-diuretic effect in nocturia. Uses: A potent, nonpeptidic vasopressin v2 receptor agonists. Synonyms: VA106483; VA-106483; VA 106483; VT483; VT-483; VT 483; Fedovapagon(2S)-N2,N2-Dimethyl-N1-[[2-methyl-4-[(2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)carbonyl]phenyl]methyl]-1,2-pyrrolidinedicarboxamide; (S)-N2,N2-Dimethyl-N1-(2-methyl-4-(2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)benzyl)pyrrolidine-1,2-dicarboxamide. Grades: ≥98%. CAS No. 347887-36-9. Molecular formula: C27H34N4O3. Mole weight: 462.59. | |
| Felbamate hydrate | The hydrate of Felbamate which is an effective anticonvulsant agent. It was found to be clinically active for probably restraining the effectivity of NMDA. Uses: The hydrate of felbamate which is an effective anticonvulsant agent. Synonyms: MLS000758238; SMR000449307; MLS001401392; CHEMBL2130858; MLS 000758238; SMR 000449307; MLS 001401392; CHEMBL 2130858; MLS-000758238; SMR-000449307; MLS-001401392; CHEMBL-2130858; HY-B0184A. Grades: 98%. CAS No. 1177501-39-1. Molecular formula: C11H16N2O5. Mole weight: 256.26. | |
| Fendiline hydrochloride | The hydrochloride salt form of Fendiline, a benzenepropanamine derivative, has been found to be a calcium channel blocker and alpha2-adrenergic receptor antagonist. It could probably restrain the proliferation of tumor cells transformed by K-Ras. IC50: 17. Uses: The hydrochloride salt form of fendiline has been found to be a calcium channel blocker and alpha2-adrenergic receptor antagonist. it could probably restrain the proliferation of tumor cells transformed by k-ras. Synonyms: FENDILINE HYDROCHLORIDE;N-[3,3-DIPHENYLPROPYL]-ALPHA-METHYLBENZYLAMINE HYDROCHLORIDE; difmecor; gamma-phenyl-n- (1-phenylethyl) benzenepropanaminehydrochloride; gamma-phenyl-n- (1-phenylethyl) -benzenepropanaminhydrochloride; hk137; n- (1-phenylethyl) -3, 3-diphenyl. Grades: 95%. CAS No. 13636-18-5. Molecular formula: C23H25N.HCl. Mole weight: 351.91. | |
| Fenmetozole Tosylate | Fenmetozole, also known as DH-524, is an antagonist of α2-adrenergic receptor and also antagonizes the actions of ethanol. Synonyms: 2-[(3,4-dichlorophenoxy)methyl]-4,5-dihydro-1H-imidazole;4-methylbenzenesulfonic acid; Fenmetozole (Tosylate). CAS No. 83474-08-2. Molecular formula: C17H18Cl2N2O4S. Mole weight: 417.31. | |
| Fenobam | Fenobam is a potent, selective, noncompetitive glutamate mGluR5 receptor antagonist. It displays inverse agonist properties. It blocks mGluR5 constitutive activity in vitro with IC50 value of 87 nM. It has been used as a lead compound for the development of a range of newer mGluR5 antagonists. It has also shown promising initial results in the treatment of fragile X syndrome. It also displays anxiolytic activity. It was developed by Johnson & Johnson and in clinic phase 2 trials with no progress. Uses: Fenobam has been used as a lead compound for the development of a range of newer mglur5 antagonists. it has also shown promising initial results in the treatment of fragile x syndrome. it also displays anxiolytic activity. Synonyms: 1-(3-Chlorophenyl)-3-(4,5-dihydro-1-methyl-4-oxo-1H-imidazol-2-yl)urea; Fenobam; NPL-2009; NPL2009; NPL 2009. Grades: >99 %. CAS No. 57653-26-6. Molecular formula: C11H11ClN4O2. Mole weight: 266.68. | |
| Fenofibrate | Fenofibrate (Tricor, Trilipix) is a compound of the fibrate class and fibric acid derivative.It is used alone or along with statins in the treatment of hypercholesterolemia and hypertriglyceridemia. Uses: Hypolipidemic agents. Synonyms: Fenofibrate, Tricor, Procetofen, Controlip, Durafenat, LF 178, LF178, LF-178, Lipanthyl, Normalip, Secalip. Grades: >98%. CAS No. 49562-28-9. Molecular formula: C20H21ClO4. Mole weight: 360.83. | |
| Fenoldopam | Fenoldopam is a selective D1 receptor partial agonist, binds to α2-adrenoceptors, increasing renal blood flow used as an antihypertensive agent. Uses: A selective d1 receptor partial agonist, binds to α2-adrenoceptors. Synonyms: 9-chloro-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;SKF 82526; SKF82526; SKF-82526. Grades: ≥98%. CAS No. 67227-56-9. Molecular formula: C16H16ClNO3. Mole weight: 305.76. | |
| Fenoldopam hydrochloride | Fenoldopam hydrochloride is a selective partial agonist of dopamine D1 receptor (EC50 = 57 nM). It also acts as an α2-adrenoceptor antagonist in vitro (Ki = 15 - 25 nM). Fenoldopam can be used as a vasodilator and antihypertensive. Uses: Vasodilator; antihypertensive. Synonyms: SR-01000075882; SR01000075882; SR 01000075882; SKF 82526 Hydrochloride; SKF82526 Hydrochloride; SKF-82526 Hydrochloride; 6-Chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-1H-3-benzazepine-7,8-diol hydrochloride. Grades: ≥98% by HPLC. CAS No. 181217-39-0. Molecular formula: C16H16ClNO3.HCl. Mole weight: 342.22. | |
| Fenoldopam Mesylate | Fenoldopam is a selective D1 receptor partial agonist, binds to α2-adrenoceptors, increasing renal blood flow used as an antihypertensive agent. Uses: Dopamine d1-receptor agonist. antihypertensive. Synonyms: 6-Chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-1H-3-benzazepine-7,8-diol; Methanesulfonate; Corlopam; Fenoldopam Methanesulfonate; Fenoldopam Monomethanesulfonate; SKF 82526J. Grades: ≥98%. CAS No. 67227-57-0. Molecular formula: C17H20ClNO6S. Mole weight: 401.86. | |
| Fenoterol hydrochloride | Fenoterol hydrochloride is a β2 adrenoreceptor agonist used as a bronchodilator for the treatment and prophylaxis of reversible bronchospasm, administered by inhalation. Synonyms: 5-[(1R)-1-hydroxy-2-[[(2R)-1-(4-hydroxyphenyl)propan-2-yl]amino]ethyl]benzene-1,3-diol;hydrochloride; Fenoterol hydrochloride; Fenoterol HCl; TH-1179 hydrochloride; TH 1179 hydrochloride; TH1179 hydrochloride; UNII-3DM11M5URG; Fenoterol hydrochloride [MI]; NSC 292265; NSC292265; NSC-292265. Grades: >98%. CAS No. 1944-10-1. Molecular formula: C17H22ClNO4. Mole weight: 339.81. | |
| FERb 033 | FERb 033 is a potent and selective ERβ receptor agonist (Ki = 7.1 nM, EC50 = 4.8 nM) with 62-fold selectivity for ERβ over ER&alpha. Synonyms: FERb 033; FERb033; FERb-033; 2-Chloro-3'-fluoro-3,4'-dihydroxy-[1,1-biphenyl]-4-carboxaldehyde oxime. Grades: ≥98% by HPLC. CAS No. 1111084-78-6. Molecular formula: C13H9ClFNO3. Mole weight: 281.67. | |
| Ferulic acid sodium | Ferulic acid sodium is one of the most abundant phenolic acids ubiquitously existing in plants. Free ferulic acid is a good antioxidant since it forms a resonancestabilized phenoxy radical. Ferulic acid showed high scavenging activity for hydrogen peroxid. Synonyms: sodium;(E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate 4-hydroxy-3-methoxycinnamic acid 8,8'-diferulic acid ferulic acid ferulic acid, (E)-isomer ferulic acid, (Z)-isomer ferulic acid, monosodium salt sodium ferulate. Grades: >98%. CAS No. 24276-84-4. Molecular formula: C10H9NaO4. Mole weight: 216.17. | |
| Fexofenadine | Fexofenadine is Histamine H1 receptor antagonist. It can be used for the treatment of allergy symptoms, such as hay fever, nasal congestion, and urticaria. Uses: Histamine h1 antagonists. Synonyms: Carboxyterfenadine; Terfenadine carboxylate; 4-[1-Hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-α,α-dimethyl-benzene-acetic Acid; 4-[4-[4-(Hydroxydiphenylmethyl)-1-piperidinyl]-1-hydroxybutyl]-α,α- dimethylphenylacetic Acid; MDL 16455; MDL16455; MDL-16455; Terfenadine Acid Metabolite. Grades: ≥98%. CAS No. 83799-24-0. Molecular formula: C32H39NO4. Mole weight: 501.66. | |
| Fezolinetant | Fezolinetant is a neurokinin 3 receptor (NK3R) antagonist used to treat sex hormone-related diseases. Synonyms: Fezolinetant; 1629229-37-3; ESN364ESN-364; UNII-83VNE45KXX. Grades: ≥98% by HPLC. CAS No. 1629229-37-3. Molecular formula: C16H15FN6OS. Mole weight: 358.4. | |
| FF-10102-01 | FF-10102-01 is a novel and selective inhibitor of spleen tyrosine kinase (Syk). Syk plays a role in downstream pathways in signaling from B-cell receptor (BCR) in B cells and Fc-gamma receptors in macrophages. FF-10102-01 exhibits an inhibitory effect on the phosphorylation of SLP76 and ERK1/2 in THP-1 cells, and on inflammation as well as thrombocytopenia. FF-10102-01 is promisingly to be a drug used for the treatment of autoimmune disease. Uses: The potential treatment of autoimmune disease. | |
| FFN 102 mesylate | FFN 102 mesylate is a selective dopamine transporter (DAT) and VMAT2 substrate with no significant binding to a panel of 38 CNS receptors. Synonyms: FFN 102 mesylate; FFN102 mesylate; FFN-102 mesylate; 4-(2-Aminoethyl)-6-chloro-7-hydroxy-2H-1-benzopyran-2-one methanesulfonate. Grades: ≥99% by HPLC. CAS No. 1883548-92-2. Molecular formula: C11H11N2ClO3.CH3SO3H. Mole weight: 335.76. | |
| FFN 200 dihydrochloride | FFN 200 dihydrochloride is a selective fluorescent VMAT2 substrate that traces exocytosis in dopaminergic neuronal cell culture and brain tissue. Synonyms: FFN 200 dihydrochloride; FFN200 dihydrochloride; FFN-200 dihydrochloride; 4-(2-Aminoethyl)-7-amino-2H-1-benzopyran-2-one dihydrochloride. Grades: ≥98% by HPLC. CAS No. 2080306-27-8. Molecular formula: C11H14Cl2N2O2. Mole weight: 277.15. | |
| FFN 206 dihydrochloride | FFN 206 dihydrochloride is a fluorescent VMAT2 substrate (IC50 app = 1.15 μM) that detects VMAT2 activity in intact cells. Synonyms: FFN 206 dihydrochloride; FFN206 dihydrochloride; FFN-206 dihydrochloride; 4-(2-Aminoethyl)-7-(methylamino)-2H-1-benzopyran-2-one dihydrochloride. Grades: ≥99% by HPLC. CAS No. 1883548-88-6. Molecular formula: C12H14N2O2.2HCl. Mole weight: 291.17. | |
| FFN 511 | FFN 511 is a fluorescent false neurotransmitter (FFN) targeting neuronal vesicular monoamine transporter (VMAT) 2 to inhibit serotonin binding to VMAT2 (IC50 = 1 μM). Synonyms: FFN 511; FFN511; FFN-511; 9-(2-Aminoethyl)-2,3,6,7-tetrahydro-1H,5H,11H-[1]-benzopyrano[6,7,8-ij]quinolizin-11-one. Grades: ≥99% by HPLC. CAS No. 1004548-96-2. Molecular formula: C17H20N2O2. Mole weight: 284.35. | |
| FG-2216 | FG-2216, also known as YM311, is an orally bioavailable HIF-prolyl hydroxylase inhibitor. FG-2216 induced significant and reversible Epo induction in vivo. Synonyms: FG 2216; FG2216; YM311; YM-311; YM 311; N-[(1-Chloro-4-hydroxyisoquinolin-3-YL)carbonyl]glycine. Grades: 98%. CAS No. 223387-75-5. Molecular formula: C12H9ClN2O4. Mole weight: 280.66. | |
| FG 7142 | FG 7142 is a benzodiazepine inverse agonist and anxiogenic agent. FG 7142 increases tyrosine hydroxylation and upregulates β-adrenoceptors in mouse cerebral cortex. Uses: Anxiogenic agent. Synonyms: FG 7142; FG7142; FG-7142; N-Methyl-β-carboline-3-carboxamide. Grades: ≥99% by HPLC. CAS No. 78538-74-6. Molecular formula: C13H11N3O. Mole weight: 225.25. | |
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