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2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis.
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. Synonyms: H-D-Tyr(tBu)-Trt(2-Cl)-Resin; H-D-Tyr(tBu)-Barlos Resin; O-(t-Butyl)-D-tyrosine 2-chlorotrityl resin.
H-D-Val-2-chlorotrityl resin
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. Synonyms: H-D-Val-Trt(2-Cl)-Resin; H-D-Val-Barlos Resin; D-Valine 2-chlorotrityl resin.
H-D-Val-Leu-Arg p-nitroanilide
Val-Leu-Arg-p-nitroanilide is a chromogenic substrate used for a convenient, sensitive, and selective assay of glandular kallikrein activity, e.g. of human and rat urinary kallikreins. Synonyms: D-Valyl-leucyl-arginine-p-nitroanilide; L-Argininamide, D-valyl-L-leucyl-N-(4-nitrophenyl)-; D-Valyl-L-leucyl-N-(4-nitrophenyl)-L-argininamide; D-Val-Leu-Arg-p-nitroanilide; D-Valyl-L-leucyl-L-arginine p-nitroanilide; (S)-2-((R)-2-Amino-3-methylbutanamido)-N-((S)-5-guanidino-1-((4-nitrophenyl)amino)-1-oxopentan-2-yl)-4-methylpentanamide; Val-Leu-Arg-p-nitroanilide. Grade: 95%. CAS No. 64816-14-4. Molecular formula: C23H38N8O5. Mole weight: 506.60.
Head activator
The neuropeptide head activator is a high-affinity ligand for the orphan G-protein-coupled receptor GPR37. Synonyms: Pglu-pro-pro-gly-gly-ser-lys-val-ile-leu-phe; Hydra Peptide; HHAP. CAS No. 79943-68-3. Molecular formula: C54H84N12O14. Mole weight: 1125.33.
Heat shock 70 kDa protein 1 (391-399)
Heat shock 70 kDa protein 1 (391-399) is a fragment of Heat shock 70 kDa protein 1. As a member of the heat shock protein 70 family and a chaperone protein, it facilitates the proper folding of newly translated and misfolded proteins, as well as stabilize or degrade mutant proteins. Synonyms: HSP70-1 (391-399).
Heat shock 70 kDa protein 1 (393-401)
Heat shock 70 kDa protein 1 (393-401) is a fragment of Heat shock 70 kDa protein 1. As a member of the heat shock protein 70 family and a chaperone protein, it facilitates the proper folding of newly translated and misfolded proteins, as well as stabilize or degrade mutant proteins. Synonyms: HSP70-1 (393-401).
Heat shock-related 70 kDa protein 2 (286-295)
Heat shock-related 70 kDa protein 2 (286-295) is a 10-aa peptide. Heat shock-related 70 kDa protein 2 plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation.
Heat shock-related 70 kDa protein 2 (446-455)
Heat shock-related 70 kDa protein 2 (446-455) is a 10-aa peptide. Heat shock-related 70 kDa protein 2 plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation.
Hedistin
Hedistin is a novel antimicrobial peptide containing bromotryptophan constitutively expressed in the NK cells-like of the marine annelid, Nereis diversicolor.
Hedyotide B1
Hedyotide B1 is from the aerial parts of Hedyotis biflora. Hedyotide B1 has a cyclic cystine knot structure typical of cyclotides.
Hejiangin-A1
Hejiangin-A1 has antibacterial and antifungal activity. The source of Hejiangin-A1 is Odorrana hejiangensis, China, Asia. Grade: >97% by HPLC.
Hejiangin-F1
Hejiangin-F1 has antibacterial and antifungal activity. The source of Hejiangin-F1 is Odorrana hejiangensis, China, Asia.
Hel 13-5
Hel 13-5 is a cell-penetrating peptide that contains Leu and Lys residues in the ratio of 13:5. It binds to DNA and forms alpha-helical structures. It is used as an efficient way for gene transfer into cells and DNA transfection. Synonyms: H-Lys-Leu-Leu-Lys-Leu-Leu-Leu-Lys-Leu-Trp-Leu-Lys-Leu-Leu-Lys-Leu-Leu-Leu-OH; L-lysyl-L-leucyl-L-leucyl-L-lysyl-L-leucyl-L-leucyl-L-leucyl-L-lysyl-L-leucyl-L-tryptophyl-L-leucyl-L-lysyl-L-leucyl-L-leucyl-L-lysyl-L-leucyl-L-leucyl-L-leucine. Grade: >98%. CAS No. 177942-21-1. Molecular formula: C113H204N24O19. Mole weight: 2202.98.
Heliomicin
Heliomicin is an antifungal protein produced by the moth Heliothis virescens, commonly known as the tobacco budworm. Heliomicin is also a type of defensin which guards against fungi, bacteria, and viruses.
Heliomicin Mutant
Heliomicin Mutant is isolated from Heliothis virescens with antibacterial and antifungal activity.
HELN_HELVI Heliocin
HELN_HELVI Heliocin is isolated from Heliothis virescens. It has antibacterial activity, preferentially against Gram-negative bacteria.
Helodermin
Helodermin is a vasoactive intestinal peptide-like peptide in the salivary gland venom of the lizard Heloderma suspectum. Synonyms: Exendin 2. CAS No. 89468-62-2. Molecular formula: C176H285N47O49. Mole weight: 3843.42.
Hepatitis B Virus Core 128-140
Hepatitis B Virus Core 128-140 is a peptide fragment of the core protein of hepatitis B virus. Synonyms: H-Thr-Pro-Pro-Ala-Tyr-Arg-Pro-Pro-Asn-Ala-Pro-Ile-Leu-OH; L-threonyl-L-prolyl-L-prolyl-L-alanyl-L-tyrosyl-L-arginyl-L-prolyl-L-prolyl-L-asparagyl-L-alanyl-L-prolyl-L-isoleucyl-L-leucine. Grade: ≥95%. CAS No. 160015-13-4. Molecular formula: C66H103N17O17. Mole weight: 1406.63.
Hepcidin
Hepcidin, a liver-derived peptide hormone, is a key regulator of systemic iron homeostasis, and its unbalanced production contributes to the pathogenesis of a spectrum of iron disorders. Hepcidin has strong antimicrobial activity against E.coli ML35P N.cinerea and weaker against S.epidermidis, S.aureus and group b streptococcus bacteria. It is active against the fungus C. albicans. Synonyms: Liver-expressed antimicrobial peptide 1.
Hepcidin-1
Hepcidin-1 is isolated from Salmo salar. Hepcidin-1 seems to act as a signaling molecule involved in the maintenance of iron homeostasis. It seems to be required in conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages. Hepcidin-1 may also have antimicrobial activity.
Hepcidin-1 (mouse)
Two kinds of hepcidin are found in mice. Hepcidin-1, a homolog of human Hepcidin-25 in serum, may be involved in murine brain iron metabolism. Hepcidin-2 is a pentapeptide with different sequences in urine. Synonyms: H-Asp-Thr-Asn-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Lys-Cys-Cys-Asn-Asn-Ser-Gln-Cys-Gly-Ile-Cys-Cys-Lys-Thr-OH (Disulfide bridge: Cys7-Cys23, Cys10-Cys22, Cys11-Cys19, Cys13-Cys14); L-alpha-aspartyl-L-threonyl-L-asparagyl-L-phenylalanyl-L-prolyl-L-isoleucyl-L-cysteinyl-L-isoleucyl-L-phenylalanyl-L-cysteinyl-L-cysteinyl-L-lysyl-L-cysteinyl-L-cysteinyl-L-asparagyl-L-asparagyl-L-seryl-L-glutaminyl-L-cysteinyl-glycyl-L-isoleucyl-L-cysteinyl-L-cysteinyl-L-lysyl-L-threonine (7->23),(10->22),(11->19),(13->14)-tetrakis(disulfide); L-α-Aspartyl-L-threonyl-L-asparaginyl-L-phenylalanyl-L-prolyl-N-[(1R,4R,7S,10S,13R,18R,21R,24S,30R,33S,36S,39S,42S,45R,50R,53S)-53-(4-aminobutyl)-18-{[(2S)-6-amino-1-{[(1S,2R)-1-carboxy-2-hydroxypropyl]amino}-1-oxo-2-hexanyl]carbamoyl}-39,42-bis(2-amino-2-oxoethyl)-33-(3-amino-3-oxopropyl)-7-benzyl-10,24-di[(2S)-2-butanyl]-36-(hydroxymethyl)-3,6,9,12,20,23,26,29,32,35,38,41,44,52,55,60-hexadecaoxo-15,16,47,48,57,58,63,64-octathia-2,5,8,11,19,22,25,28,31,34,37,40,43,51,54,61-hexadecaazatetracyclo[28.25.4.44,21.245,50]pentahexacont-13-yl]-L-isoleucinamide. Grade: ≥95%. CAS No. 1676104-75-8. Molecular formula: C111H169N31O35S8. Mole weight: 2754.28.
Hepcidin-2
Hepcidin-2 is isolated from Mus musculus. It seems to act as a signaling molecule involved in the maintenance of iron homeostasis.
Hepcidin-20 (human)
Hepcidin-20 is a fragment of Hepcidin. Hepcidin is a protein that in humans is encoded by the HAMP gene. Grade: >96%. CAS No. 342790-23-2. Molecular formula: C85H135N27O23S9. Mole weight: 2191.73.
Hepcidin-22 (human)
Hepcidin-22 (human) is an inactive degradation product of Hepcidin-25 found in human urine. Synonyms: H-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Gly-Cys-Cys-His-Arg-Ser-Lys-Cys-Gly-Met-Cys-Cys-Lys-Thr-OH (Disulfide bridge: Cys4-Cys10, Cys7-Cys20, Cys8-Cys19, Cys11-Cys16, air oxidized); L-phenylalanyl-L-prolyl-L-isoleucyl-L-cysteinyl-L-isoleucyl-L-phenylalanyl-L-cysteinyl-L-cysteinyl-glycyl-L-cysteinyl-L-cysteinyl-L-histidyl-L-arginyl-L-seryl-L-lysyl-L-cysteinyl-glycyl-L-methionyl-L-cysteinyl-L-cysteinyl-L-lysyl-L-threonine (4->10),(7->20),(8->19),(11->16)-tetrakis(disulfide). Grade: ≥95%. CAS No. 342790-22-1. Molecular formula: C99H151N29O25S9. Mole weight: 2436.06.
Hepcidin-24 (human)
Hepcidin-24, an excellent substitute for biotinylated or heavy isotope-labeled hepcidin-25, is used as an internal reference in the determination of Hep-25 by mass spectrometry-based methods, for example in human serum or urine. Synonyms: H-Thr-His-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Gly-Cys-Cys-His-Arg-Ser-Lys-Cys-Gly-Met-Cys-Cys-Lys-Thr-OH (Disulfide bridge: Cys6-Cys22, Cys9-Cys12, Cys10-Cys18, Cys13-Cys21, air oxidized); des-Asp1-Hepcidin-24. Grade: ≥95%. Molecular formula: C109H165N33O28S9. Mole weight: 2674.31.
Hepcidin 3
Hepcidin 3 was found in Epinephelus moara. It has antimicrobial activity.
Hepcidin 5
Hepcidin 5 was found in Epinephelus moara. It has antimicrobial activity.
Hepcidin antimicrobial peptide 1
Hepcidin antimicrobial peptide 1 is produced by Danio rerio.
Hepcidin-like antimicrobial peptide precursor
Hepcidin-like antimicrobial peptide precursor is an antibacterial peptide isolated from Channa argus (snakehead). Synonyms: Leu-Glu-Glu-Ala-Gly-Ser-Asn-Asp-Thr-Pro-Val-Ala-Ala-His-Gln-Glu-Met-Ser-Thr-Glu-Ser-Trp-Met-Met-Pro-Asn-His-Ile-Arg-Gln-Lys-Arg-Gln-Ser-His-Ile-Ser-Leu-Cys-Arg-Tyr.
Hepcidin TH1-5
Hepcidin TH1-5 has been demonstrated to be effective against Nervous necrosis virus infection in medaka (Oryzias latipes).
hepcidin TH2-3
Hepcidin TH2-3, a synthetic 20-mer antimicrobial peptide, specifically inhibited human fibrosarcoma cell (HT1080 cell line) proliferation and migration.
Heptapeptide-10
Heptapeptide-10 is a synthetic peptide composed of the amino acids arginine, glutamine, glycine, lysine, phenylalanine, serine, and threonine. It is known for its ability to improve skin tolerance and reduce sensitivity, making it beneficial for those with sensitive skin conditions. This peptide has been shown to have anti-inflammatory effects and can help in the management of skin health by reducing the symptoms of certain skin conditions such as psoriasis, which is characterized by an overactive immune system. In cosmetic applications, Heptapeptide-10 is used as a skin conditioning agent to maintain the skin in good condition. It is also recognized for its potential role in anti-wrinkle and anti-aging products due to its ability to influence skin cell behavior and promote a healthier skin appearance. The peptide is considered to have good compatibility with the skin and is easily absorbed, contributing to its effectiveness in skincare formulations. Overall, Heptapeptide-10 is a valuable ingredient in the field of cosmetology for its multifaceted benefits in skin health and appearance.
HER2/neu (654-662) GP2
HER2/neu (654-662) GP2 is a 9 amino acid peptide derived from the human epidermal growth factor receptor 2. Synonyms: GP2; H-Ile-Ile-Ser-Ala-Val-Val-Gly-Ile-Leu-OH; L-isoleucyl-L-isoleucyl-L-seryl-L-alanyl-L-valyl-L-valyl-glycyl-L-isoleucyl-L-leucine. Grade: ≥95%. CAS No. 160790-21-6. Molecular formula: C42H77N9O11. Mole weight: 884.11.
HER-2/neu (85-94)
HER-2/neu (85-94) is an epitope from the extracellular region of Human Epidermal Growth Factor Receptor-2. It has shown its capacity to induce both cellular and humoral immune response in vivo. Grade: >95%. Molecular formula: C51H88N18O14. Mole weight: 1177.3599999999999.
HERV-K-MEL (1-9)
HERV-K-MEL (1-9) is a 9-aa peptide. The HERV-K-MEL antigen is encoded by a pseudo-gene incorporated in the HERV-K env-gene. HERV-K-MEL is significantly expressed in the majority of dysplastic and normal naevi, as well as other tumors like sarcoma, lymphoma, bladder and breast cancer.
HEX3 acetate
HEX3 acetate is a fragment of the adenoviral hexon which is the major capsid protein found in Adenoviruses and is comprised of three identical polypeptide chains. Synonyms: L-Isoleucine, L-lysyl-L-tyrosyl-L-seryl-L-prolyl-L-seryl-L-asparaginyl-L-valyl-L-lysyl-, acetate salt (1:1); L-Lysyl-L-tyrosyl-L-seryl-L-prolyl-L-seryl-L-asparaginyl-L-valyl-L-lysyl-L-isoleucine acetate salt; Lys-Tyr-Ser-Pro-Ser-Asn-Val-Lys-Ile acetate salt. Grade: ≥95%. Molecular formula: C47H78N12O14.C2H4O2. Mole weight: 1095.26.
Hexapeptide-10
Hexapeptide-10. CAS No. 146439-94-3. Molecular formula: C28H53N7O8. Mole weight: 615.76.
Hexapeptide-10 Acetate
Hexapeptide-10 Acetate is a synthetic peptide. It increases the synthesis of laminin V and α6-integrin to promote cell binding, with extraordinary visible skin restructuring and firming abilities. Molecular formula: C30H57N7O10. Mole weight: 675.81.
Hexapeptide 11
Hexapeptide-11, a synthetic peptide widely used as an anti-aging ingredient in cosmetics, reduces the appearance of fine lines and wrinkles and is an excellent addition to a variety of skin care and anti-aging products. Hexapeptide-11 regulates collagen levels, improves skin elasticity, increases skin firmness, supplements polyligand proteoglycan deficiency in aging skin, improves epidermal adhesion, and makes skin look more shiny and even. Synonyms: L-Phenylalanyl-L-valyl-L-alanyl-L-prolyl-L-phenylalanyl-L-proline; L-Proline, 1-[N-[1-[N-(N-L-phenylalanyl-L-valyl)-L-alanyl]-L-prolyl]-L-phenylalanyl]-; Peptamide 6; H-Phe-Val-Ala-Pro-Phe-Pro-OH; H-FVAPFP-OH. Grade: >95%. CAS No. 161258-30-6. Molecular formula: C36H48N6O7. Mole weight: 676.80.
Hexapeptide-33
Hexapeptide-33 is a biologically active peptide that has been reported for use in cosmetics due to its multifaceted benefits for the skin. It is known to stimulate blood vessel formation and is developed under the trade name W3 peptide by Novacell Technology. This peptide consists of the amino acids arginine, leucine, lysine, phenylalanine, serine, and tyrosine. It has been proven to have skin whitening effects, contribute to wound healing, reduce wrinkles, promote cell migration, and stimulate collagen synthesis while inhibiting melanin synthesis. Hexapeptide-33 also acts as an antioxidant, directly inhibiting tyrosinase during melanin biosynthesis, which reduces the synthesis of melanin and inhibits the activity of tyrosinase in melanoma B16 cells. It is used in skincare for its whitening properties, induced angiogenesis in human endothelial cells, and accelerated wound healing. It also promotes hair growth and eyelash growth. Synonyms: H-Ser-Phe-Lys-Leu-Arg-Tyr-OH; H-SFKLRY-OH; SFKLRY; L-Seryl-L-phenylalanyl-L-lysyl-L-leucyl-L-arginyl-L-tyrosine. Grade: ≥95%. CAS No. 1192135-40-2. Molecular formula: C39H60N10O9. Mole weight: 812.96.
Hexapeptide-9 Acetate
Hexapeptide-9 is an anti-aging hexapeptide that helps strengthening structural tissues by naturally interacting with skin cells thereby promoting the rejuvenation process. Molecular formula: C26H42N8O11. Mole weight: 642.66.
HEZ-PBAN
HEZ-PBAN is a neuropeptide hormone that activates pheromone biosynthesis and induces sex pheromone synthesis in various moth species in the picomolar range. Synonyms: HeA-PBAN; H-Leu-Ser-Asp-Asp-Met-Pro-Ala-Thr-Pro-Ala-Asp-Gln-Glu-Met-Tyr-Arg-Gln-Asp-Pro-Glu-Gln-Ile-Asp-Ser-Arg-Thr-Lys-Tyr-Phe-Ser-Pro-Arg-Leu-NH2; Pheromone Biosynthesis Activating Neuropeptide (Helicoverpa assulta, Heliothis zea); L-leucyl-L-seryl-L-alpha-aspartyl-L-alpha-aspartyl-L-methionyl-L-prolyl-L-alanyl-L-threonyl-L-prolyl-L-alanyl-L-alpha-aspartyl-L-glutaminyl-L-alpha-glutamyl-L-methionyl-L-tyrosyl-L-arginyl-L-glutaminyl-L-alpha-aspartyl-L-prolyl-L-alpha-glutamyl-L-glutaminyl-L-isoleucyl-L-alpha-aspartyl-L-seryl-L-arginyl-L-threonyl-L-lysyl-L-tyrosyl-L-phenylalanyl-L-seryl-L-prolyl-L-arginyl-L-leucinamide. Grade: ≥95% by HPLC. CAS No. 122071-54-9. Molecular formula: C167H259N47O57S2. Mole weight: 3901.31.
HFIAP-1
HFIAP-1 is a polycationic peptide with broad-spectrum bactericidal activity isolated from Myxine glutinosa (Atlantic hagfish). It has activity against gram-positive bacteria and gram-negative bacteria. Synonyms: Gly-Phe-Phe-Lys-Lys-Ala-Trp-Arg-Lys-Val-Lys-His-Ala-Gly-Arg-Arg-Val-Leu-Asp-Thr-Ala-Lys-Gly-Val-Gly-Arg-His-Tyr-Val-Asn-Asn-Trp-Leu-Asn-Arg-Tyr-Arg. Grade: 97.0%. Mole weight: 4643.3.
HFIAP-3
HFIAP-3 is a polycationic peptide with broad-spectrum bactericidal activity isolated from Myxine glutinosa (Atlantic hagfish). It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Gly-Trp-Phe-Lys-Lys-Ala-Trp-Arg-Lys-Val-Lys-Asn-Ala-Gly-Arg-Arg-Val-Leu-Lys-Gly-Val-Gly-Ile-His-Tyr-Gly-Val-Gly-Leu-Ile. Grade: 95.7%. Mole weight: 3551.9.
H-γ-azido-Abu-OH
L-Azidohomoalanine is a PROTAC linker, which is composed of alkyl chains. L-Azidohomoalanine can be used to synthesize a range of PROTACs. Uses: A novel mutagenic amino acid. Synonyms: L-Azidohomoalanine HCl salt; H-Dab(N2)-OH; L-γ-azidohomoalanine; H-γ-Aha-OH; (2S)-4-azido-2-aminobutyric acid; H-Abu(N3)-OH; L-Azidohomoalanine; (S)-2-Amino-4-azidobutanoic acid; 4-Azido-L-2-aminobutyrate; L-2-Amino-4-azidobutanoic acid. Grade: ≥95%. CAS No. 120042-14-0. Molecular formula: C4H8N4O2. Mole weight: 144.13.
H-γ-GLU-GLN-OH is an intestinal metabolite which may be related to myocardial infarction in rats. Synonyms: gamma-Glutamylglutamine; (5-L-Glutamyl)-L-glutamine; H-Glu(Gln-OH)-OH; N2-gamma-Glutamylglutamine; N2-L-γ-Glutamyl-L-glutamine. CAS No. 10148-81-9. Molecular formula: C10H17N3O6. Mole weight: 275.26.
HGAPDH is an antibacterial peptide isolated from Homo sapiens. It has activity against gram-negative bacteria and fungi. Synonyms: Gly-Lys-Val-Lys-Val-Gly-Val-Asn-Gly-Phe-Gly-Arg-Ile-Gly-Arg-Leu-Val-Thr-Arg-Ala-Ala-Phe-Asn-Ser-Gly-Lys-Val-Asp-Ile-Val-Ala. Grade: 98.0%.
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. Synonyms: L-Gln-2-chlorotrityl resin; L-Glutamine-2-chlorotrityl resin.
H-Gln-Gln-OH
It is a substrate for glutaminyl cyclase. Synonyms: Gln-Gln; Glutaminyl-Glutamine; QQ dipeptide; L-Gln-L-Gln; Glutamine Glutamine dipeptide. CAS No. 54419-93-1. Molecular formula: C10H18N4O5. Mole weight: 274.27.
H-Gln-Glu-OH
H-Gln-Glu-OH can be used to study the metal binding affinity between Nickel (II) and oligopeptides containing aspartyl and glutamyl residues. Synonyms: Gln-Glu; L-glutaminyl-L-glutamic acid; QE dipeptide; L-Gln-L-Glu; Glutamine Glutamate dipeptide. CAS No. 88830-90-4. Molecular formula: C10H17N3O6. Mole weight: 275.26.
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. Synonyms: H-Gln(Trt)-Trt(2-Cl)-Resin; H-Gln(Trt)-Barlos Resin; N-δ-Trityl-L-glutamine 2-chlorotrityl resin.
H-Gln(Trt)-Gly-OH
H-Gln(Trt)-Gly-OH is a dipeptide used in peptide synthesis. The H indicates a free N-terminus, meaning there is no protective group on the amino group of the first amino acid, Gln (Glutamine). The side chain of glutamine is protected by a Trt (Trityl) group, which prevents the side chain amide from participating in unwanted reactions during synthesis. Gly (Glycine) is the second amino acid in the sequence, known for its small and flexible nature. The -OH at the C-terminus indicates a free carboxyl group, allowing the dipeptide to be further extended in peptide synthesis. This compound is used to incorporate glutamine and glycine into peptides, with specific protections in place to ensure selective reactions. Synonyms: N5-Trityl-L-glutaminylglycine; QG. Grade: ≥95%. Molecular formula: C26H27N3O4. Mole weight: 445.52.
H-Glu-Ala-Leu-Phe-Gln-pNA
The substrate EALFQ-pNA representing the 2C/3A cleavage site of human rhinovirus-14 (HRV-14) polyprotein is hydrolyzed by human rhinovirus-14 3C protease, which is an attractive target for antiviral drug development. It shows a kcat/Km value of 840 M-1s-1. Synonyms: L-Glutamamide, L-α-glutamyl-L-alanyl-L-leucyl-L-phenylalanyl-N1-(4-nitrophenyl)-; L-α-Glutamyl-L-alanyl-L-leucyl-L-phenylalanyl-N1-(4-nitrophenyl)-L-glutamamide; (4S,7S,10S,13S,16S)-1,16-diamino-7-benzyl-10-isobutyl-13-methyl-4-((4-nitrophenyl)carbamoyl)-1,6,9,12,15-pentaoxo-5,8,11,14-tetraazanonadecan-19-oic acid; H-EALFQ-pNA. Grade: 95%. CAS No. 198551-00-7. Molecular formula: C34H46N8O10. Mole weight: 726.78.
H-Glu-Ala-OH
H-Glu-Ala-OH. Synonyms: Glu-ala; glutamyl-alanine; N-L-alpha-glutamyl-L-alanine; alpha-glutamylalanine; H Glu Ala OH. Grade: 99%. CAS No. 21064-18-6. Molecular formula: C8H14N2O5. Mole weight: 218.2072.
H-Glu-AMC
H-Glu-AMC is a fluorogenic substrate for aminopeptidase a, producing a blue fluorescent solution upon cleavage. Synonyms: Glu-NH-med; (S)-4-Amino-5-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-5-oxopentanoic acid; (4S)-4-amino-5-[(4-methyl-2-oxochromen-7-yl)amino]-5-oxopentanoic acid; 7-(alpha-Glutamyl)-4-methylcoumarylamide; alpha-Glutamyl-7-amino-4-methylcoumarylamide; L-Glutamic acid alpha-(7-amido-4-methylcoumarin). Grade: ≥ 95%. CAS No. 98516-76-8. Molecular formula: C15H16N2O5. Mole weight: 304.30.
H-Glu[cyclo(-Arg-Gly-Asp-D-Phe-Lys)]-cyclo(-Arg-Gly-Asp-D-Phe-Lys) is the dimeric form of c(RGDfK), which has better tumor-targeting properties than the monomer. It binds readily to dyes, drug molecules, or chelators. The 68Ga complex of DOTA-E(c(RGDfK))2 has been evaluated as a therapeutic radiopharmaceutical. Synonyms: Cyclo[D-Phe-N6-[N5-[3-[[cyclo(L-Ala-L-Arg-Gly-L-Asp-D-Phe-)]-3-yl]propyl]-L-Gln-]-L-Lys-L-Arg-Gly-L-Asp-]; E(c(RGDfK))2; SU 016. Grade: ≥95%. CAS No. 250612-47-6. Molecular formula: C59H87N19O16. Mole weight: 1318.44.
H-Glu(EDANS)-Lys-Pro-Ala-Lys-Phe-Phe-Arg-Leu-Lys(DABCYL)-NH2 is a quenched fluorescent (FRET) substrate for ADAM 8, ADAM 15 and MDC-L (ADAM 28) but not for ADAM 17. For ADAM 8 half maximal cleavage was observed at 2.5 μM. Synonyms: L-Lysinamide, N-[2-[(5-sulfo-1-naphthalenyl)amino]ethyl]-L-glutaminyl-L-lysyl-L-prolyl-L-alanyl-L-lysyl-L-phenylalanyl-L-phenylalanyl-L-arginyl-L-leucyl-N6-[4-[2-[4-(dimethylamino)phenyl]diazenyl]benzoyl]-; 5-((2-((S)-4-amino-5-(((S)-6-amino-1-((S)-2-(((7S,10S,13S,16S,19S,22S,25S)-22-(4-aminobutyl)-16,19-dibenzyl-7-carbamoyl-1-(4-((E)-(4-(dimethylamino)phenyl)diazenyl)phenyl)-13-(3-guanidinopropyl)-10-isobutyl-1,9,12,15,18,21,24-heptaoxo-2,8,11,14,17,20,23-heptaazahexacosan-25-yl)carbamoyl)pyrrolidin-1-yl)-1-oxohexan-2-yl)amino)-5-oxopentanamido)ethyl)amino)naphthalene-1-sulfonic acid. Grade: ≥95%. CAS No. 1926163-42-9. Molecular formula: C88H124N22O15S. Mole weight: 1762.12.
H-Glu(EDANS)-Pro-Leu-Phe-Ala-Glu-Arg-Lys(DABCYL)-OH is an internally quenched substrate for calpain-1 (μ-calpain) with optimal cleavage motifs flanking the scissile bond. The turnover rate of the enzyme to hydrolysis of this FRET substrate based on the PLFAER amino acid sequence is more than 18 times higher than that of EVYGMM derived from the natural substrate α-spectrin cleavage site. Synonyms: N-({5-[(2-Aminoethyl)amino]-1-naphthyl}sulfonyl)-L-α-glutamyl-L-prolyl-L-leucyl-L-phenylalanyl-L-alanyl-L-α-glutamyl-L-arginyl-N6-(4-{[4-(dimethylamino)phenyl]diazenyl}benzoyl)-L-lysine. Grade: ≥95%. CAS No. 1914987-47-5. Molecular formula: C72H97N17O16S. Mole weight: 1488.71.