BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Tranilast Sodium | Tranilast, an allergic media blocker, is effective for the treatment of asthma and is also used to treat asthma, allergic rhinitis and other allergic disorders. Uses: Tranilast, an allergic media blocker, is effective for the treatment of asthma and is also used to treat asthma, allergic rhinitis and other allergic disorders. Synonyms: Tranilast (Sodium); HS-0009; HS 0009; HS0009; Tranilast sodium; HY-B0195A; AKOS015994603; AKOS025392158. Grades: 98%. CAS No. 104931-56-8. Molecular formula: C18H16NNaO5. Mole weight: 349.31. |  |
| (±)trans-2,5-bis-(3,4,5-Trimethoxyphenyl)-1,3-dioxolane | Trans-BTP Dioxolane is a PAF receptor antagonist. This compound demonstrates competitive antagonism of PAF in a rabbit washed platelet assay (Ki = 0.3 μM). Synonyms: trans-BTP Dioxolane; trans-(±)-2,4-bis(3,4,5-trimethoxyphenyl)-1,3-dioxolane; (2R,4R)-2,4-bis(3,4,5-trimethoxyphenyl)-1,3-dioxolane. Grades: ≥98%. CAS No. 116673-45-1. Molecular formula: C21H26O8. Mole weight: 406.4. | |
| Trans-4-(guanidinomethyl)-cyclohexane-L-YL-D-3-cyclohexylalanyl-L-azetidine-2-YL-D-tyrosinyl-L-homoargininamide | Trans-4-(guanidinomethyl)-cyclohexane-L-YL-D-3-cyclohexylalanyl-L-azetidine-2-YL-D-tyrosinyl-L-homoargininamide, a biomedical marvel, unveils its unparalleled potential in studying a myriad of ailments. Synonyms: DB04697; PD005894; TRANS-4-(GUANIDINOMETHYL)-CYCLOHEXANE-L-YL-D-3-CYCLOHEXYLALANYL-L-AZETIDINE-2-YL-D-TYROSINYL-L-HOMOARGININAMIDE; N-{[ (2S) -1- (N-{[cis-4- (carbamimidamidomethyl) cyclohexyl]carbonyl}-3-cyclohexyl-D-alanyl) azetidin-2-yl]carbonyl}-D-tyrosyl-N~6~-carbamimidoyl-L-lysinamide. Molecular formula: C38H61N11O6. Mole weight: 767.96. | |
| (±)-trans-ACPD | (±)-trans-ACPD has been found to be a mGluR2 agonist. Uses: Neuroprotective agents. Synonyms: (±)-1-Aminocyclopentane-trans-1,3-dicarboxylic acid. Grades: ≥99% by HPLC. CAS No. 67684-64-4. Molecular formula: C7H11NO4. Mole weight: 173.17. | |
| trans-Ned 19 | trans-Ned 19, a structural analog of NAADP, is a nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist.trans-Ned 19 inhibits NAADP-mediated Ca2+ release (IC50 = 6 nM), and also inhibits [32P]NAADP binding (IC50 = 0.4 nM). It can be used as a chemical proble since it fluorescentey labels NAADP receptors in intact cells. Synonyms: (1R,3S)-1-[3-[[4-(2-Fluorophenyl)piperazin-1-yl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid; Ned-19; Ned 19; Ned19. Grades: ≥98% by HPLC. CAS No. 1354235-96-3. Molecular formula: C30H31FN4O3. Mole weight: 514.59. | |
| Transtinib | This active molecular is an irreversible EGFR ( epidermal growth factor receptor ) tyrosine kinase inhibitor. Transtinib shows good anti-proliferative activity against the H1975 and A431 cell lines and IC50 values is 34 nM and 62 nM. In xenograft models, Transtinib decreases tumor size for a prolonged period of time. Transtinib may become a drug candidate for the inhibition of mutant EGFR to overcome the development of resistance. Uses: Anti-cancer. Synonyms: (S,E)-N-(4-((3-chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)-7-ethoxyquinazolin-6-yl)-3-(pyrrolidin-2-yl)acrylamide. Grades: 98%. CAS No. 1246089-27-9. Molecular formula: C30H29ClFN5O3. Mole weight: 562.04. | |
| trans-Tranilast | Trans-Tranilast is an antiallergic drug used to treat bronchial asthma, allergic rhinitis and atopic dermatitis. Uses: Antiallergic drug, used to treat bronchial asthma, allergic rhinitis and atopic dermatitis. Synonyms: Tranilast; Rizaben; SB-252218; SB 252218; SB252218; 2-[[(2E)-3-(3,4-Dimethoxyphenyl)-1-oxo-2-propen-1-yl]amino]benzoic Acid; (E)-2-[[3-(3,4-Dimethoxyphenyl)-1-oxo-2-propenyl]amino]benzoic Acid. Grades: ≥95%. CAS No. 70806-55-2. Molecular formula: C18H17NO5. Mole weight: 327.33. | |
| trans-Triprolidine hydrochloride | Trans-Triprolidine hydrochloride is a potent histamine H1 receptor antagonist with anticholinergic properties. Triprolidine is used for the treatment and prevention of allergy. Uses: Antihistaminic agent. Synonyms: 295 C 51, Actidil, Actidilat, Entra, Pro-Actidil, Pro-Entra, Triprolidine HCl, Triprolidine hydrochloride, Triprolidine hydrochloride anhydrous, Venen; (E)-2-[1-(4-Methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl]pyridine hydrochloride; Triprolidine hydrochloride. Grades: ≥99% by HPLC. CAS No. 550-70-9. Molecular formula: C19H22N2.HCl. Mole weight: 314.86. | |
| Trap 101 | Trap 101 is a potent and selective nociceptin/orphanin FQ (NOP) receptor antagonist (pA2 = 7.75) with selectivity for NOP receptors over classical opioid receptors (pKi = 8.65, 6.60, 6.14 and <5 for NOP, μ-, κ-, and δ-opioid receptors, respectively). Trap 101 attenuates motor deficits in a rat model of Parkinson's Disease. Synonyms: 2H-Benzimidazol-2-one, 1-[1-(cyclooctylmethyl)-1,2,3,6-tetrahydro-5-(hydroxymethyl)-4-pyridinyl]-3-ethyl-1,3-dihydro-; 1-[1-(Cyclooctylmethyl)-1,2,3,6-tetrahydro-5-(hydroxymethyl)-4-pyridinyl]-3-ethyl-1,3-dihydro-2H-benzimidazol-2-one; Trap-101; Trap101; 1-[1-(cyclooctylmethyl)-5-(hydroxymethyl)-3,6-dihydro-2H-pyridin-4-yl]-3-ethyl-2-benzimidazolone. Grades: ≥95%. CAS No. 873567-76-1. Molecular formula: C24H35N3O2. Mole weight: 397.55. | |
| Trapoxin A | Trapoxin A is an irreversible cyclotetrapeptide histone deacetylase (HDAC) inhibitor. It inhibits HDAC activity in a concentration-dependent and irreversible manner. Uses: Antibiotics, antineoplastic. Synonyms: Cyclo((S)-phenylalanyl-(S)-phenylalanyl-(R)-pipecolinyl-(2S,9S)-2-amino-8-oxo-9,10-epoxydecanoyl). Grades: ≥98%. CAS No. 133155-89-2. Molecular formula: C34H42N4O6. Mole weight: 602.72. | |
| Trastuzumab | Trastuzumab is a monoclonal antibody drug for the treatment of breast cancer which is HER2 receptor positive. It acts via binding to HER2 receptor to suppress cell duplication. Uses: The treatment of her2 receptor positive breast cancer. Synonyms: Herceptin; RhuMab HER2; Anti HER2, Ig gamma-1 chain C region; Recombinant humanized anti-HER2 antibody; IMMunoglobulin G1,anti-(huMan p185neu receptor) (huMan-Mouse Monoclonal rhuMab HER2 g1-chain), disulfide with huMan-MouseMonoclonal rhuMab HER2 light chain, diMer. CAS No. 180288-69-1. Molecular formula: C10H14N6O5. Mole weight: 145kda. | |
| Traxoprodil mesylate | Traxoprodil mesylate is a NR2B selective antagonist of NMDA glutamate receptors. Synonyms: CP 101606 mesylate; CP101606 mesylate; CP-101606 mesylate; 1-[(1S,2S)-1-hydroxy-1-(4-hydroxyphenyl)propan-2-yl]-4-phenylpiperidin-4-ol mesylate. Grades: 99%. CAS No. 188591-67-5. Molecular formula: C20H25NO3.CH4O3S. Mole weight: 423.52. | |
| TRC051384 | TRC051384 is a heat shock protein 70 (HSP70) inducer. Synonyms: 1-(2-morpholin-4-ylethyl)-3-[4-[(E)-3-(6-morpholin-4-ylpyridin-2-yl)prop-2-enoyl]phenyl]urea; 1-(2-(morpholin-4-yl)ethyl)-3-(4-(-3-(6-(morpholin-4-yl)pyridin- 2-yl)prop-2-enoyl)phenyl)urea dihydrochloride; TRC051384; TRC 051384; TRC-051384. CAS No. 867164-40-7. Molecular formula: C25H31N5O4. Mole weight: 465.54. | |
| Trecadrine | Trecadrine, a new β3-adrenergic agonist, decreases fat content and increases gastrocnemius muscle UCP2 gene expression in a diet-induced obesity model. Synonyms: (1R,2S)-2-[2-(5,6-dihydrodibenzo[1,2-a:1',2'-e][7]annulen-11-ylidene)ethyl-methylamino]-1-phenylpropan-1-ol; (1- ( (2- (10, 11-dihydro-5H-dibenzo (a, d) cyclohepten-5-ylidene) ethyl) methylamino) ethy) benzyl alcohol; trecadrine. CAS No. 90845-56-0. Molecular formula: C27H29NO. Mole weight: 383.53. | |
| Trelagliptin | Two Phase II clinical studies have been completed with Efficacy and Safety of SYR-472 in Subjects With Type 2 Diabetes Mellitus. Phase III clinical studies with trelagliptin in Japan to evaluate its safety and efficacy in a once-weekly oral treatment regimen. Currently, all available DPP-4 inhibitors are dosed once-daily. A once-weekly treatment, such as trelagliptin, would provide patients with a convenient treatment alternative and has the potential to improve treatment compliance. Synonyms: SYR-472; SYR472; SYR 472. Grades: 0.98. CAS No. 865759-25-7. Molecular formula: C18H20FN5O2. Mole weight: 357.389. | |
| Trelagliptin succinate | Trelagliptin is a long acting dipeptidyl peptidase-4 (DPP-4) inhibitor that is being developed for the treatment of type 2 diabetes (T2D). Synonyms: (R)-2-((6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzonitrile succinate; SYR472; SYR472; SYR 472; Trelagliptin, Trelagliptin succinate; brand name: Zafatek. Grades: >98%. CAS No. 1029877-94-8. Molecular formula: C22H26FN5O6. Mole weight: 475.47. | |
| Tremelimumab | A human immunoglobulin (Ig) G2 monoclonal antibody directed against the human T-cell receptor protein cytotoxic T-lymphocyte-associated protein 4 (CTLA4), with potential immune checkpoint inhibitory and antineoplastic activities. Tremelimumab binds to CTLA4 on activated T-lymphocytes and blocks the binding of the antigen-presenting cell ligands B7-1 (CD80) and B7-2 (CD86) to CTLA4, resulting in inhibition of CTLA4-mediated downregulation of T-cell activation. This promotes the interaction of B7-1 and B7-2 with another T-cell surface receptor protein CD28, and results in a B7-CD28-mediated T-cell activation that is unopposed by CTLA4-mediated inhibition. This leads to a cytotoxic T-lymphocyte (CTL)-mediated immune response against cancer cells. CTLA4, an inhibitory receptor and member of the immunoglobulin superfamily, plays a key role in the downregulation of the immune system. Synonyms: CP-675; CP 675; CP675; CP-675,206. CAS No. 745013-59-6. | |
| Trequinsin hydrochloride | Trequinsin hydrochloride is a highly potent inhibitor of cGMP-inhibited phosphodiesterase (PDE3) (IC50 = 250 pM). Trequinsin stimulates cAMP accumulation at a concentration of 10 μM, and inhibits arachidonic acid-induced platelet aggregation (IC50 = 50 pM). Trequinsin was shown to decrease blood pressure levels in both normotensive and hypertensive animal models and is used as an antihypertensive agent. Uses: Antihypertensive agent. Synonyms: 2,3,6,7-Tetrahydro-9,10-dimethoxy-3-methyl-2-[(2,4,6-trimethylphenyl)imino]-4H-pyrimido[6,1-a]isoquinolin-4-one hydrochloride. Grades: ≥97% by HPLC. CAS No. 78416-81-6. Molecular formula: C24H27N3O3.HCl. Mole weight: 441.95. | |
| Triadimenol | Triadimenol is a agricultural fungicide that is systemically active against powdery mildews and rusts of grains. lt is a systemic fungicide with a broad spectrum. It inhibits the ergosterol - and gibberellin - biosynthesis. Uses: Triadimenol is a agricultural fungicide that is systemically active against powdery mildews and rusts of grains. Synonyms: UK 199; UK-199; UK199; Baytan;Bayfidan;Spinnaker;Summit;1-(4-Chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-ol;UK-199;UK199;1,2,4-Triazole-1-ethanol, beta-(4-chlorophenoxy)-alpha-(1,1-dimethylethyl)-;Beta-(4-chlorophenoxy)-alpha-(1,1-dimethylethyl)-1H-1,2,4-triazole-. Grades: 98%. CAS No. 55219-65-3. Molecular formula: C14H18ClN3O2. Mole weight: 295.76. | |
| Triapine | 3-Aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP) is a ribonucleotide reductase inhibitor and iron chelator with anti-tumor activity. Synonyms: 3AP; 3AP; 3Apct; OCX 191; OCX191; OCX191; AIDS179996; AIDS179996; NSC663249. PAN-811; PAN811; PAN 811; Triapine. Grades: >98%. CAS No. 143621-35-6. Molecular formula: C7H9N5S. Mole weight: 195.24. | |
| Triflumuron | Triflumuron is a chitin synthesis inhibitor. It inhibits the synthesis of chitin by the insect larvae, causing the die. It is a benzoylphenylurea insecticide used to control insects pests such as mosquitos and flies. It is applied to pears, apples, peaches, mushrooms and nectarines. It is also used in the storage of cereals. Uses: Triflumuron is a benzoylphenylurea insecticide used to control insects pests such as mosquitos and flies. Synonyms: STARYCIDE; Trifluron; TRIFLUMURON; Mascot; bay sir 8514; BAYCIDAL; ALSYSTIN; 2-chloro-n- ( ( (4- (trifluoromethoxy) phenyl) amino) carbonyl) benzamide. Grades: USP. CAS No. 64628-44-0. Molecular formula: C15H10ClF3N2O3. Mole weight: 358.7. | |
| trifluoperazine | Trifluoperazine is a typical antipsychotic of the phenothiazine chemical class with anti-adrenergic and anti-dopaminergic actions just similar to Chlorpromazine. It is a Dopamine Receptor antagonist. The primary application of trifluoperazine is for schizophrenia but it also be used for other psychiatric disorders including severe anxiety and disturbed behaviours. Uses: Schizophrenia. Synonyms: 10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine. Grades: 98%. CAS No. 117-89-5. Molecular formula: C21H24F3N3S. Mole weight: 407.5. | |
| Triflupromazine | Triflupromazine, a phenothiazin derivative, has been found to be a D2 dopamine receptor antagonist that could probably used as a tranquilizer and antipsychotic agent. Synonyms: Dimethyl(3-(2-trifluoromethylphenothiazin-10-yl)propyl)amine; fluopromazine; triflupromazine; TRIFLUOROPROMAZINE; 10-[3-(Dimethylamino)propyl]-2-(trifluoromethyl)-10H-phenothiazine; Trifluopromazine. Grades: 98%. CAS No. 146-54-3. Molecular formula: C18H19F3N2S. Mole weight: 352.42. | |
| Triflupromazine Hydrochloride | The hydrochloride salt form of Triflupromazine, an analogue of Chlorpromazine, is effective as nntipsychotic drug and antemetic agent. Uses: The hydrochloride salt form of triflupromazine is effective as nntipsychotic drug and antemetic agent. Synonyms: 10- (3- (dimethylamino) propyl) -2- (trifluoromethyl) -phenothiazinmonohydrochlo; 10- (3-dimethylaminopropyl) -2- (trifluoromethyl) phenothiazinehydrochloride; n, n-dimethyl-2- (trifluoromethyl) -10h-phenothiazine-10-propanaminmonohydr; trifluopromazinehydrochloride; TRI. Grades: 95%. CAS No. 1098-60-8. Molecular formula: C18H20ClF3N2S. Mole weight: 388.88. | |
| Trihexylphenedyl | Trihexyphenidyl is a Mucarinic Cholinergic receptor antagonist using for the treatment of Parkinson's disease. It also has a direct antispasmodic action on smooth muscle. Uses: Parkinson's disease. Synonyms: Trihexyphenidyl; Benzhexol; Triphenidyl; Parkinane retard; Trihexyphenidyle; Benzhexolum;1-cyclohexyl-1-phenyl-3-piperidin-1-ylpropan-1-ol;52-49-3(Trihexyphenidyl Hydrochloride). Grades: 98%. CAS No. 144-11-6. Molecular formula: C20H31NO. Mole weight: 301.47. | |
| Trilaciclib | Trilaciclib is a CDK4/6 inhibitor with IC50 of 1 nM and 4 nM, respectively. It is developed to reduce the burden of chemotherapy-induced myelosuppression in patients with small cell lung cancer. Synonyms: G1T28. CAS No. 1374743-00-6. Molecular formula: C24H30N8O. Mole weight: 446.5. | |
| TRIM | TRIM is a potent inhibitor of neuronal and inducible NO synthases (nNOS and iNOS), but exhibits lower affinity for the endothelial isoform (IC50 = 28.2, 27.0 and 1057.5 μM, respectively). Synonyms: 1-(2-Trifluoromethylphenyl)imidazole; 1-[2-(Trifluoromethyl)phenyl]imidazole. Grades: ≥99% by HPLC. CAS No. 25371-96-4. Molecular formula: C10H7F3N2. Mole weight: 212.17. | |
| Trimebutine | Trimebutine is an agonist of peripheral mu, kappa and delta opiate receptors, used as spasmolytic agent for treatment of both acute and chronic abdominal pain. Uses: Gastrointestinal agents. Synonyms: Mebutin. Grades: >98%. CAS No. 39133-31-8. Molecular formula: C22H29NO5. Mole weight: 387.47. | |
| Trimethaphan | Trimetaphan camsilate can counteract cholinergic transmission at the ganglion type of nicotinic receptors of the autonomic ganglia and this lead to block both the sympathetic nervous system and the parasympathetic nervous system. Trimetaphan camsilate is a non-depolarizing competitive antagonist at the nicotinic acetylcholine receptor. Uses: Hypertension. Synonyms: Thieno(1',2':1,2)thieno(3,4-d)imidazol-5-ium, decahydro-2-oxo-1,3-bis(phenylmethyl)- (VAN). Grades: 98%. CAS No. 7187-66-8. Molecular formula: C22H25N2OS. Mole weight: 365.52. | |
| Trimetrexate | Trimetrexate is a potent competitive inhibitor of bacterial, protozoan, and mammalian dihydrofolate reductase. Synonyms: CI-898; CI 898; CI898. Grades: >98%. CAS No. 52128-35-5. Molecular formula: C19H23N5O3. Mole weight: 369.42. | |
| Trimipramine Maleate | Trimipramine Maleate is a tricyclic antidepressant for the treatment of depression and depression accompanied by anxiety. Uses: Antidepressant. Synonyms: 10,11-Dihydro-N,N,β-trimethyl-5H-dibenz[b,f]azepine-5-propanamine (2Z)-2-butenedioate; Surmontil Maleate; Trimeprimine Maleate; Trimeprimine Monomaleate. Grades: ≥98%. CAS No. 521-78-8. Molecular formula: C24H30N2O4. Mole weight: 413.52. | |
| Trimopam | Trimopam is a dopamine receptor agonist. Synonyms: 7,8-dimethoxy-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepine; 2,3,4,5-tetrahydro-7,8-dimethoxy-3-methyl-1-phenyl-1H-3-benzazepine;d-7,8-dimethoxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine;N-methyl-1-phenyl-7,8-dimethoxy-2,3,4,5-tetrahydro-3-benzazepine;SCH-12679; SCH 12679; SCH12679trimopam;trimopam, (R)-isomer;trimopam, maleate, (1:1), (R)-isomer;Sch 2679; Sch12679. Grades: >98%. CAS No. 20012-08-2. Molecular formula: C19H23NO2. Mole weight: 297.398. | |
| Triolimus | Triolimus is composed of a micelle containing the drugs rapamycin, 17-AAG, and paclitaxel, which act synergistically to inhibit tumor growth. | |
| Triprolidine hydrochloride hydrate | Triprolidine hydrochloride hydrate is a potent H1 histamine receptor antagonist. It is used in allergic rhinitis, urticaria and asthma. It is an over-the-counter antihistamine with anticholinergic property. It is used to treat the symptoms associated with allergies and is sometimes combined with other cold medications to relieve flu-like symptoms. It was developed by GlaxoSmithKline and has been listed. Uses: Triprolidine hydrochloride is used in allergic rhinitis, urticaria and asthma. it is used to treat the symptoms associated with allergies and is sometimes combined with other cold medications to relieve flu-like symptoms. Synonyms: Triprolidine Hydrochloride Monohydrate; 2-[(E)-1-(4-methylphenyl)-3-pyrrolidin-1-ylprop-1-enyl]pyridine hydrate hydrochloride. Grades: 98%. CAS No. 6138-79-0. Molecular formula: C19H22N2.HCl.H2O. Mole weight: 332.872. | |
| Tromantadine | Tromantadine is a topical antiherpetic drug that has two independent actions on herpes simplex virus type 1 (HSV-1) replication: early, during virus binding or penetration and late, after the initiation of DNA synthesis. Synonyms: N-(1-adamantyl)-2-[2-(dimethylamino)ethoxy]acetamide; D 41; N-(1-adamantyl)-2-(2-dimethylaminoethoxy)acetamide; tromantadin; tromantadine; tromantadine monohydrochloride; tromantadine monohydrochloride, monohydrate; tromantidine; Viru-Merz; Viru-Merz serol; Viru-Serol. Grades: ≥99.0%. CAS No. 53783-83-8. Molecular formula: C16H28N2O2. Mole weight: 280.41. | |
| Tropanyl-3,5-dimethylbenzoate | Tropanyl-3,5-dimethylbenzoate is a 5-HT3 receptor antagonist. Synonyms: Tropanserin; MDL-72422; MDL 72422; MDL72422; [(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 3,5-dimethylbenzoate. Grades: ≥99%. CAS No. 85181-40-4. Molecular formula: C17H23NO2. Mole weight: 273.37. | |
| Trotabresib | Trotabresib is a reversible inhibitor of epigenetic target bromodomain and extra-terminal (BET) protein with anti-tumor activity. Synonyms: CC 90010; CC-90010. Grades: >98%. CAS No. 1706738-98-8. Molecular formula: C21H21NO4S. Mole weight: 383.5. | |
| Trovirdine | Trovirdine, a thiourea non-nucleoside reverse transcriptase inhibitor, was shown to inhibits HIV-1 RT when employing heteropolymeric primer/template (oligo-DNA/ribosomal RNA)and dGTP as substrate but inhibits has no development reported recently. IC50: HI. Synonyms: 1-(5-bromopyridin-2-yl)-3-(2-pyridin-2-ylethyl)thiourea LY 300046 LY-300046 LY300046.HCl N-(2-(2-pyridyl)ethyl)-N'-(2-(5-bromo)pyridyl)thiourea hydrochloride trovirdine. Grades: 99.43%. CAS No. 149488-17-5. Molecular formula: C13H13BrN4S. Mole weight: 337.24. | |
| TRPV antagonist 1 | TRPV antagonist 1 is a transient receptor potential vanilloid (TRPV) antagonist (IC50= < 250 nM). Synonyms: 5H-Thiazolo[3,2-a]pyrimidin-5-one, 7-[(1E)-2-[2-(cyclopropylmethoxy)-3-methoxyphenyl]ethenyl]-6-[4-(trifluoromethoxy)phenyl]-. CAS No. 1192871-27-4. Molecular formula: C26H21F3N2O4S. Mole weight: 514.52. | |
| TRx 0237 | TRx 0237, also called LMT-X or Methylene Blue, is a second-generation tau protein aggregation inhibitor currently in development for the treatment of Alzheimer's disease (AD) and frontotemporal dementia. Synonyms: TRx 0237; TRx0237; TRx-0237; 3-N,3-N,7-N,7-N-tetramethyl-10H-phenothiazine-3,7-diamine; leucomethylene blue; leukomethylene blue; Panatone; 613-11-6; N,N,N',N'-Tetramethyl-10H-phenothiazine-3,7-diamine; N3,N3,N7,N7-tetramethyl-10H-phenothiazine-3,7-diamine; leucoform; Reduced methylene blue. CAS No. 613-11-6. Molecular formula: C17H21N3S1. Mole weight: 285.41. | |
| TT15 | TT15 is an agonist of glucagon-like peptide-1R (GLP-1R). Synonyms: AC-31475; TT-15; TT 15. Grades: ≥98% by HPLC. CAS No. 1187061-63-7. Molecular formula: C51H44Cl2N4O6. Mole weight: 879.8. | |
| TTA-A2 | TTA-A2 is a selective T-type calcium channel antagonist and an effective anticonvulsant. Synonyms: (R)-2-(4-cyclopropylphenyl)-N-(1-(5-(2,2,2-trifluoroethoxy)pyridin-2-yl)ethyl)acetamide. Grades: 98%. CAS No. 953778-63-7. Molecular formula: C20H21F3N2O2. Mole weight: 378.4. | |
| TTA-P2 | TTA-P2 is a selective T-type calcium channel blocker. It blocks T-type currents with an IC50 of 100 nM and stabilized channel in the inactive state in rats DRGs. TTA-P2 potentially acts as an antinociceptive and an antiinflammatory agent. Synonyms: TTA-P2; TTA P2; TTAP2; (S)-3,5-Dichloro-N-((1-((2,2-dimethyltetrahydro-2H-pyran-4-yl)methyl)-4-fluoropiperidin-4-yl)methyl)benzamide; CHEMBL488817; 3,5-dichloro-N-[[4-fluoro-1-[[(4S)-tetrahydro-2,2-dimethyl-2H-pyran-4-yl]methyl]-4-piperidinyl]methyl]Benzamide; 3,5-Dichloro-N-[(1-{[(4S)-2,2-dimethyloxan-4-yl]methyl}-4-fluoropiperidin-4-yl)methyl]benzamide. CAS No. 1072018-68-8. Molecular formula: C21H29Cl2FN2O2. Mole weight: 431.373. | |
| TTK21 | TTK21 is an activator of CBP/p300 histone acetyltransferase activity that activates CBP/p300 histone acetyltransferase activity in a concentration-dependent manner. Synonyms: N-[4-chloro-3-(trifluoromethyl)phenyl]-2-propoxybenzamide. Grades: ≥98%. CAS No. 709676-56-2. Molecular formula: C17H15ClF3NO2. Mole weight: 357.8. | |
| Tubastatin A HCl salt | Tubastatin A is a potent and selective HDAC6 inhibitor. Tubastatin A was substantially more selective than the known HDAC6 inhibitor Tubacin at all isozymes except HDAC8. Tubastatin A is a potent HDAC6 inhibitor with an IC50 value of 15 nM. Tubastatin A induces α-tubulin hyperacetylation at 2.5 μM in primary cortical neuron cultures. In a model of oxidative stress induced by glutathione depletion, tubastatin A displays dose-dependent neuronal protection of primary cortical neuron cultures at 5-10 μM. Grades: 0.98. CAS No. 1310693-92-5. Molecular formula: C20H22ClN3O2. Mole weight: 371.865. | |
| Tubastatin A trifluoroacetate salt | Tubastatin A is a potent HDAC6 inhibitor with IC50 value of 15 nM. Tubastatin A induces α-tubulin hyperacetylation at 2.5 μM in primary cortical neuron cultures. In a model of oxidative stress induced by glutathione depletion, tubastatin A displays dose-dependent neuronal protection of primary cortical neuron cultures at 5-10 μM. Synonyms: N-Hydroxy-4-((2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)methyl)benzamide 2,2,2-trifluoroacetate. Grades: ≥95%. CAS No. 1239262-52-2. Molecular formula: C20H21N3O2·CF3COOH. Mole weight: 449.4. | |
| Tubocurarine hydrochloride pentahydrate | Cas No. 6989-98-6. | |
| Tubulin Inhibitor 6 | Tubulin inhibitor 6 is a tubulin inhibitor and an effective inhibitor of a variety of cancer cell lines. Synonyms: IHAP1; 2-Chloro-10-(4-Methoxybenzoyl)-10H-Phenothiazine; (2-Chloro-10H-Phenothiazin-10-Yl)(4-Methoxyphenyl)Methanone; Oprea1_789892. Grades: 98%. CAS No. 105925-39-1. Molecular formula: C20H14ClNO2S. Mole weight: 367.8. | |
| TUG424 | TUG424 is a a potent and selective free fatty acid receptor 1 agonist. It is expected to be useful in the exploration of FFA1 and may also be valuable as a lead structure for new potential antidiabetic therapeutics. Uses: Tug424 may be valuable as a lead structure for new potential antidiabetic therapeutics. Synonyms: TUG-424; TUG424; TUG 424; 4-[2-(2-methylphenyl)ethynyl]-benzenepropanoicacid;CAY10587;3-(4-(o-Tolylethynyl)phenyl)propanoic acid; TUG-424; 3-[4-[ (2-Methylphenyl) ethynyl]phenyl]propanoic acid. Grades: >99 %. CAS No. 1082058-99-8. Molecular formula: C18H16O2. Mole weight: 264.32. | |
| TUG-469 | This active molecular is a free fatty acid (FFA) 1 receptor agonist. TUG-469 is more than two hundred fold selective for FFA1 over FFA4. TUG-469 can potential use for the treatment of type 2 diabetes mellitus as a selectively FFA1 inhibitor. Activation of the FFA1 leads to an enhancement of glucose-stimulated insulin secretion from pancreatic β-cells. Uses: Type 2 diabetes mellitus. Synonyms: TUG469; TUG 469; TUG-469; 4-[[(2'-Methyl[1,1'-biphenyl]-3-yl)methyl]amino]benzenepropanoic Acid; 3-(4-(((2'-Methyl-[1,1'-biphenyl]-3-yl)methyl)amino)phenyl)propanoic Acid. Grades: 98%. CAS No. 1236109-67-3. Molecular formula: C23H23NO2. Mole weight: 345.44. | |
| Tulobuterol hydrochloride | Tulobuterol hydrochloride is a salt form of Tulobuterol, which is a long-acting beta2-adrenergic receptor agonist. Synonyms: 2-tert-Butylamino-1-(2-chlorophenyl)-ethanol hydrochloride. Grades: 99.69%. CAS No. 56776-01-3. Molecular formula: C12H19Cl2NO. Mole weight: 264.19. | |
| TW-37 | TW-37, a small-molecule inhibitor of Bcl-2, inhibits cell growth and induces apoptosis in pancreatic cancer mediated through a novel pathway involving inactivation of Notch-1 and Jagged-1. Synonyms: TW37; TW 37; TW-37. Grades: 0.95. CAS No. 877877-35-5. Molecular formula: C33H35NO6S. Mole weight: 573.7. | |
| TX1-85-1 | TX1-85-1 is an inhibitor of the epidermal growth factor receptor tyrosine kinase ErbB3 (IC50 = 23 nM). It is the first selective HER3 ligand that interacts with cys721 in the ATP-binding pocket of HER3. Synonyms: EX-A2880; N-[5-[1-[4-(4-Acetylpiperazin-1-yl)cyclohexyl]-4-aminopyrazolo[3,4-d]pyrimidin-3-yl]-2-phenoxyphenyl]prop-2-enamide. Grades: ≥98%. CAS No. 1603845-32-4. Molecular formula: C32H36N8O3. Mole weight: 580.7. | |
| TYK2-IN-2 | TYK2-IN-2 is an inhibitor of TYK2 with potential for the treatment of inflammatory and autoimmune diseases. Synonyms: 6-(3,5-dimethylanilino)-8-(methylamino)imidazo[1,2-b]pyridazine-3-carboxamide. CAS No. 2098466-94-3. Molecular formula: C16H18N6O. Mole weight: 310.35. | |
| Tylosin phosphate | Tylosin phosphate is a broad spectrum antibiotic against Gram-positive organisms and a limited range of Gram-negative organisms. Synonyms: Tylan; Farmazin TB; Pharmasine TB; Tylan 40 premix; Tylan 10 premix. Grades: >98%. CAS No. 1405-53-4. Molecular formula: C46H80NO21P. Mole weight: 1014.1. | |
| Tyrosine kinase inhibitor | It is a Tyrosine kinase inhibitor. Synonyms: Tyrosine kinase inhibitor; MDK-0264; MDK0264; MDK 0264; B-Raf IN, B-Raf Inhibitor. Grades: >98%. CAS No. 1021950-26-4. Molecular formula: C31H31FN6O5. Mole weight: 586.61. | |
| Tyrphostin 9 | Tyrphostin 9 is firstly designed as an EGFR inhibitor with IC50 of 460 μM, but is also found to be more potent to PDGFR with IC50 of 0.5 μM. Synonyms: SF 6847, RG 50872; SF6847, RG50872; SF-6847, RG-50872. Grades: >98%. CAS No. 10537-47-0. Molecular formula: C18H22N2O. Mole weight: 282.38. | |
| Tyrphostin AG-528 | Tyrphostin AG-528, also known as Tyrphostin B66, is an inhibitor of EGFR and ErbB2 with IC50s of 4.9 and 2.1 μM, respectively. Synonyms: Tyrphostin AG-528; Tyrphostin AG 528; Tyrphostin AG528; (E)-1-[2-cyano-3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]-2,3-dihydro-1H-Indole; (αE)-α-[(3,4-Dihydroxyphenyl)methylene]-2,3-dihydro-β-oxo-1H-indole-1-propanenitrile; AG 528; 1-[(2E)-2-cyano-3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]-2,3-dihydro-1H-Indole. CAS No. 133550-49-9. Molecular formula: C18H14N2O3. Mole weight: 306.32. | |
| Tyrphostin B44, (-) enantiomer | Tyrphostin B44, (-) enantiomer is a potent inhibitor of epidermal growth factor receptor (EGFR) kinase (IC50 = 0.4 μM). More active than the (+) enantiomer. Synonyms: (R)-(E)-2-Cyano-3-(3',4'-dihydroxyphenyl)-N-(1-phenylethyl)-2-propenamide. CAS No. 133550-32-0. Molecular formula: C18H16N2O3. Mole weight: 308.34. | |
| Tyrphostin B44, (+) enantiomer | Tyrphostin B44, (+) enantiomer is an inhibitor of epidermal growth factor receptor (EGFR) kinase (IC50 = 0.86 μM). Less active than the (-) enantiomer. Synonyms: (S)-(E)-2-Cyano-3-(3',4'-dihydroxyphenyl)-N-(1-phenylethyl)-2-propenamide. CAS No. 133550-37-5. Molecular formula: C18H16N2O3. Mole weight: 308.34. | |
| U0124 | U0124 is an inactive analog of U0126 that can be used as a negative control. U0124 has no inhibitory effects on MEK at concentrations up to 100 μM. Synonyms: U0124; U 0124; U-0124; Bis[amino (methylthio) methylene]butanedinitrile. CAS No. 108923-79-1. Molecular formula: C8H10N4S2. Mole weight: 226.31. | |
| U0126-EtOH | U0126-EtOH is a highly selective inhibitor of MEK1/2 with IC50 of 0.07 μM/0.06 μM, 100-fold higher affinity for ΔN3-S218E/S222D MEK than PD98059. Synonyms: U0126-EtOH; U0126EtOH; U0126 EtOH, U0126, U-0126, U 0126. Grades: >98%. CAS No. 1173097-76-1. Molecular formula: C18H16N6S2.C2H6O. Mole weight: 426.56. | |
| U 18666A | U 18666A is a cell-permeable and amphiphilic amino-steroid that inhibits cholesterol synthesis and cellular transport via the suppression of 2,3-oxidosqualene-lanosterol cyclase activity. U 18666A also acts as a weak inhibitor of hedgehog (Hh) signaling. It has been shown to reduce serum sterol levels in rats in vivo. Synonyms: U-18666A; U 18666A; U18666A; U 18666 A; U-18666-A; NSC-70801; NSC 70801; NSC70801; (3β)-3-[2-(Diethylamino)ethoxy]androst-5-en-17-one hydrochloride. Grades: ≥98% (HPLC). CAS No. 3039-71-2. Molecular formula: C25H41NO2.HCl. Mole weight: 424.07. | |
| (-)-U-50488 hydrochloride | (-)-U-50488 hydrochloride is the more active enantiomer of (±)-U-50488, which is an opioid receptor agonist. Synonyms: (-)-U-50488 hydrochloride; (-)-U 50488 hydrochloride; (-)-U50488 hydrochloride; trans- (-) -3, 4-Dichloro-N-methyl-N-[2- (1-pyrrolidinyl) cyclohexyl]benzeneacetamide hydrochloride; (-)-trans-(1S,2S)-U-50488 hydrochloride. Grades: ≥99% by HPLC. CAS No. 114528-79-9. Molecular formula: C19H26Cl2N2O.HCl. Mole weight: 405.79. | |
| (+)-U-50488 hydrochloride | (+)-U-50488 hydrochloride is the less active enantiomer of (±)-U-50488, which is an opioid receptor agonist. Synonyms: (±)-U-50488 hydrochloride; (±)-U 50488 hydrochloride; (±)-U50488 hydrochloride; trans-(+)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)-cyclohexyl]benzeneacetamide hydrochloride; (+)-trans-(1R,2R)-U-50488 hydrochloride. Grades: ≥99% by HPLC. CAS No. 114528-81-3. Molecular formula: C19H26Cl2N2O.HCl. Mole weight: 405.79. | |
| (±)-U-50488 hydrochloride | (±)-U-50488 hydrochloride is a selective κ-opioid agonist with no μ-opioid antagonist effects. (±)-U-50488 hydrochloride blocks Na+ channels at high concentrations. Uses: Analgesics, non-narcotic. Synonyms: (±)-U-50488 hydrochloride; (±)-U 50488 hydrochloride; (±)-U50488 hydrochloride; trans- (±) -3, 4-Dichloro-N-methyl-N-[2- (1-pyrrolidinyl) cyclohexyl]benzeneacetamide hydrochloride. Grades: ≥99% by HPLC. CAS No. 67197-96-0. Molecular formula: C19H26Cl2N2O.HCl. Mole weight: 405.79. | |
| U-54494A hydrochloride | U-54494A hydrochloride is a κ-opioid agonist and a potential NMDA antagonist. U-54494A hydrochloride is used as an anticonvulsant. Uses: Anticonvulsant. Synonyms: cis-(±)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzamide hydrochloride. CAS No. 112465-94-8. Molecular formula: C18H24Cl2N2O.HCl. Mole weight: 391.77. | |
| U66858 | U66858, also known as Bunaprolast, is a hydroquinone inhibitor of leukotriene synthesis, which inhibits LTB4 production in human whole blood. Synonyms: (2-butyl-4-methoxynaphthalen-1-yl) acetate; 1-acetoxy-2-n-butyl-4-methoxynaphthalene; bunaprolast; U 66,858; U 66858; U-66,858; U-66858. CAS No. 99107-52-5. Molecular formula: C17H20O3. Mole weight: 272.34. | |
| U-73122 | U-73122 is a phospholipase C inhibitor originated by Pharmacia Corporation and IC 50 value is 1.0-2.1 μM in neutrophils and human platelets. U-73122 can be used as a tool to investigate the involvement of the PLC (phosphoinositide-specific phospholipase C) in signal transduction, especially in reseraches trying to characterize pathways leading to intracellular Ca2+ mobilization upon agonist challenge. Preclinical trials for treatment of Thrombosis was discontinued in 1998. Uses: Thrombosis. Synonyms: U-73122; U 73122; U73122; 1-(6-(((8R,9S,13S,14S,17S)-3-methoxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione. Grades: 95%. CAS No. 112648-68-7. Molecular formula: C29H40N2O3. Mole weight: 464.64. | |
| U-75302 | U-75302 is a selective LTB4 receptor antagonist with Ki value of 159 nM on guinea pig lung membranes. Synonyms: U 75302; U75302; 6-(6-(3-Hydroxy-1,5-undecadien-1-yl)-2-pyridinyl)-1,5-hexanediol. Grades: ≥98%. CAS No. 119477-85-9. Molecular formula: C22H35NO3. Mole weight: 361.5. | |
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